Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CGP 20376 是一种苯并噻唑化合物,是一种驱虫剂,对嗜酸性粒细胞呼吸爆发的双重剂量依赖性调节体外作用,具有抗纤特性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 2,090 | 现货 | ||
5 mg | ¥ 4,970 | 现货 | ||
10 mg | ¥ 7,250 | 现货 | ||
25 mg | ¥ 10,700 | 现货 | ||
50 mg | ¥ 14,500 | 现货 |
产品描述 | CGP 20376 is a benzothiazole compound, an anthelmintic, with dual dose-dependent modulation of in vitro effects on the respiratory burst of eosinophils and antifibrillatory properties. |
体外活性 | CGP 20376 (1 micron/ml) reduction of motility of 98-100% after 24 hours of exposure occurred at levels. After exposure for 1 h CGP 20376 immobilized 100% of the microfilariae irreversibly at a drug level of 1 microgram/ml. Whereas no significant immobilization was seen with CGP 6140 after one hour.[5] |
体内活性 | CGP 20376 (20 mg/kg orally) had a rapid and profound reduction, but by 137 d.p.t. microfilarial skin densities were approaching pre-treatment levels. By 137 d.p.t. embryogenesis was almost completely interrupted in the CGP 20376 treated animals and the majority of remaining intrauterine microfilariae were pathologically altered.[1] |
别名 | CGP-20376, CGP20376 |
分子量 | 384.54 |
分子式 | C16H20N2O3S3 |
CAS No. | 81059-04-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
CGP 20376 81059-04-3 CGP-20376 CGP20376 Inhibitor inhibitor inhibit