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Search Results for " phosphorylase "

53

抑制剂 & 化合物

10

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1056	Phosphorylase Kinase β-Subunit Fragment (420-436) Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436
	Phosphorylase Kinase β-Subunit Fragment (420-436) is a peptide fragment (430-436) derived from the β-Subunit of phosphorylase kinase. Phosphorylase kinase, a serine/threonine-specific protein kinase, plays a crucial role in the activation of glycogen phosphorylase for the release of glucose-1-phosphate from glycogen[1].
T37577	Glycogen Phosphorylase Inhibitor
	Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic glycogenolysis in vivo. Glycogen phosphorylase inhibitor has been used to study glycogen utilization in human liver HepG2 cells, retinal explants, and human T lymphocyte Kit 225 cells.
T76103	Sucrose phosphorylase
	Sucrose phosphorylase 是一种bacterium转葡萄糖苷酶，专门催化蔗糖与磷酸盐反应形成 α-D-葡萄糖-1-磷酸和 D-果糖。此外，该酶通过glucosylation作用可以水解产生 α-D-葡萄糖或将glucosyl group转移至目标hydroxyl group，进而合成新的 α-D-葡萄糖苷。它对底物与产物的hydrolase活性表现出较弱的反应性。
T76100	Maltose phosphorylase
	Maltose phosphorylase 是一种二聚酶，负责催化麦芽糖与无机磷酸盐转化成 β-D-葡萄糖-1-磷酸盐及葡萄糖。该酶归类于糖苷水解酶第65族。
T76096	Purine nucleoside phosphorylase
	Purine nucleoside phosphorylase 是嘌呤代谢中的关键酶，参与嘌呤挽救途径。Purine nucleoside phosphorylase 缺乏导致 T 细胞功能受损。在无机正磷酸盐作为第二底物的存在下，Purine nucleoside phosphorylase 催化核糖和脱氧核糖核苷的糖苷键断裂，生成嘌呤碱和核糖（脱氧核糖）-1-磷酸。
T9727	2'-Fluoro-2'-Deoxyadenosine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2′-Deoxy-2′-fluoroadenosine 可用于合成2 ' -脱氧-2 ' -氟修饰的寡核苷酸。它能被大肠杆菌嘌呤核苷磷酸化酶（PNP）有效地分解成毒性物 2-氟腺嘌呤，对表达大肠杆菌 PNP 的肿瘤表现出良好的体内活性。
T75401	D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)
	D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)，属于CAZy糖苷水解酶GH112家族，主要应用于生化研究领域。该酶负责催化lacto-N-biose和lacto-N-neobiose的磷酸化反应，生成Gal-1-磷酸和相应的N-乙酰-D-己糖胺。
T12399	Peldesine BCX 34	Nucleoside Antimetabolite/Analog; HIV Protease	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Peldesine (BCX 34) 是一种有效的、竞争性的、可逆的和口服活性的嘌呤核苷磷酸化酶抑制剂。 Peldesine 抑制 T 细胞增殖，IC50 为 800 nM。 Peldesine 可用于皮肤 T 细胞淋巴瘤、牛皮癣和 HIV 感染的研究。
T14141	AGI-24512	Others; Methionine Adenosyltransferase (MAT)	Chromatin/Epigenetic; Others
	AGI-24512 是一种甲硫氨酸腺苷转移酶 2A 抑制剂，在体外能够阻断 MTAP 缺失的癌细胞的生长，可用于研究癌症。
T75398	UDP-sugar pyrophosphorylase (BlUSP)
	UDP-sugar pyrophosphorylase (BlUSP) 是一种酶，其功能是将葡萄糖-1-磷酸(Glc-1-P)转化为UDP-葡萄糖(UDP-Glc)。该酶通过催化UTP的尿苷基到糖-1-磷酸的可逆转移，进而产生UDP-糖和焦磷酸(PPi)。
T8493	Ingliforib GPi 296,CP 368296	Phosphorylase	Metabolism
	Ingliforib (CP 368296) 是glycogen phosphorylase 抑制剂，能够抑制肝脏、肌肉和大脑的 glycogen phosphorylase ，其IC50值分别为 52，352 和 150 nM，具有心脏保护的作用。
T0745	Disodium monofluorophosphate Sodium Monofluorophosphate,单氟磷酸钠,NSC248	Phosphatase; PKM; Phosphorylase	Metabolism
	Disodium monofluorophosphate (NSC248) 是丙酮酸激酶和碱性磷酸酶的竞争性抑制剂，它也不可逆地抑制磷酸化酶磷酸酶。
T6745	5-Iodotubercidin 5-碘代杀结核菌素,5-ITu,NSC 113939	Adenosine Receptor	GPCR/G Protein; Neuroscience
	5-Iodotubercidin (NSC-113939) 是一种 ATP 类似物，有效抑制腺苷激酶，IC50为 26 nM。它可以激活磷酸化酶和糖原合成酶，在离体肝细胞中启动糖原合成。它也抑制 CK1、胰岛素受体酪氨酸激酶、磷酸化酶激酶、PKA、CK2、PKC 和 Haspin 。
T7782	3'-Deoxyguanosine	Others	Others
	3'-Deoxyguanosine 是一种配体，可与酶如嘌呤核苷磷酸化酶和受体复合。
TQ0008	MT-DADMe-ImmA Methylthio-DADMe-Immucillin A,MTDIA	Others	Others
	MT-DADMe-ImmA (MTDIA) 是一种人5'-甲硫基腺苷磷酸化酶的抑制剂 (MTAP)(Ki:90 pM)。
T15337	Forodesine 呋咯地辛,BCX-1777,Immucillin-H	Others	Others
	Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could induce apoptosis in leukemic cells b
T22683	CP-316819 CP 316819,GPi 819	Others	Others
	CP-316819 (GPi 819) 是一种高效的糖原磷酸化酶 (GPase) 抑制剂，具有降血糖作用，抑制 huSMGPa 和 huLGPa，可在低血糖期间维持神经元活性，可用于研究高血糖。
T10421	AVE5688	Phosphorylase	Metabolism
	AVE5688 是糖原磷酸化酶 (glycogen phosphorylase (GP)) 抑制剂，抑制兔肌肉糖原磷酸化酶 rmGPb 和 rmGPa 的活性，IC50 值分别为 430 nM 和 915 nM，Kd 值分别为 170 nM 和 530 nM；AVE5688 可用于二型糖尿病的研究。
T67822L	Ulodesine BCX4208	Endogenous Metabolite	Metabolism
	Ulodesine (BCX4208) 是一种嘌呤核苷磷酸化酶 (PNP) 抑制剂，对 PNP 有抑制作用，IC50 值为 2.293 nM/L。Ulodesine 可用于研究高尿酸血症。
T2366	Tipiracil hydrochloride MA-1 hydrochloride,盐酸替吡嘧啶	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Tipiracil hydrochloride (MA-1 hydrochloride) 是一种胸苷磷酸化酶抑制剂，是抗癌候选药物 TAS-102 中的活性成分之一，用于癌症研究。
T6455	CP-91149	Phosphorylase	Metabolism
	CP91149 是GP (糖原磷酸化酶)的抑制剂，能够促进糖原的重新合成，但不会造成糖原的过度积累。它对2型糖尿病具有潜在的研究价值。
TNU0091	3'-Deoxy-3'-fluoroguanosine	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	3'-Deoxy-3'-fluoroguanosine 是一种核苷磷酸化酶抑制剂，通过结合复制子抑制RNA的复制。3'-Deoxy-3'-fluoroguanosine 可用于治疗病毒性肝炎、癌症和其他疾病。
T12908	SIBA 5'-Deoxy-5'-isobutylthioadenosine,5'-Isobutylthioadenosine,5ˊ-异丁硫基-5ˊ-脱氧腺苷	Nucleoside Antimetabolite/Analog; HSV	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	SIBA (5'-Deoxy-5'-isobutylthioadenosine) 是 SAH 的合成类似物，可作为 S-腺苷甲硫氨酸介导的甲基转移的抑制剂。它干扰多种酶活性，可逆地阻断单纯疱疹病毒 1 型病毒的繁殖。
T1349	5-Fluorouridine	Others; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	5-Fluorouridine 是一种 5-fluorouracil 的代谢物，具有抗癌作用。它对 L1210 细胞的生长具有细胞毒性作用，其作用的 IC50值为 2 nM。它能抑制人结肠癌细胞 rRNA 的合成。
T1600	Doxifluridine Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Doxifluridine (AMC 0101) 是一种胸苷磷酸化酶活化剂，对 PC9-DPE2细胞的 IC50为0.62 μM。它是具有抗肿瘤活性的抗肿瘤剂 5-fluorouracil (5-FU) 的氟嘧啶衍生物和口服前药。
T14964	CI 972 anhydrous CI 972 (anhydrous)	Others	Others
	CI 972 anhydrous is an inhibitor of purine nucleoside phosphorylase (PNP) (Ki: 0.83 μM) used as a T cell-selective immunosuppressive agent.
T22803	GPi 688	Others	Others
	glycogen phosphorylase inhibitor
T68524	AVE 9423
	AVE 9423 is an allosteric glycogen phosphorylase inhibitor.
T70768	MDL-74428
	MDL-74428 is an inhibitor of purine nucleoside phosphorylase.
T70939	8-Aminoinosine
	8-Aminoinosine is an endogenous 8-aminopurine that induces diuresis, natriuresis, and glucosuria by inhibiting purine nucleoside phosphorylase (PNPase).
T19148	5-Aza-7-deazaguanine	Others	Others
	5-Aza-7-deazaguanine is a substrate for E. coli purine nucleoside phosphorylase (wild-type/Ser90Ala mutant) in the synthesis of base-modified nucleosides.
TNU1023	7-Deaza-2’-deoxyadenosine
	Nucleoside Derivatives –7-Deaza-purine nucleosides; Drugs and Inhibitors; Purine nucleoside phosphorylase inhibitor
T40410	Maltoheptaose hydrate
	Maltoheptaose hydrate, a maltooligosaccharide composed of seven glucose units, serves as an activator of phosphorylase B for the preparation of heptulose-2-phosphate.
T60343	Tipiracil
	Tipiracil 是胸苷磷酸化酶 (TPase)的抑制剂。
T12162	N6-Methyladenosine 5'-monophosphate disodium salt	Others	Others
	N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator(Ka of 22 µM).
T40932	Benzylacyclouridine 5-Benzylacyclouridine,BAU
	Benzylacyclouridine (BAU) is a powerful and selective inhibitor of uridine phosphorylase, the initial enzyme involved in uridine catabolism. Additionally, it can regulate the cytotoxic adverse effects of 5-fluorouracil (5-FU) and its derivatives.
T62931	Antiangiogenic agent 2
	Antiangiogenic agent 2 (compound 3b) 是一种有效的胸苷磷酸化酶 (thymidine phosphorylase) 抑制剂 (IC50: 39.71 μM)，表现出抗血管生成作用。
T31048	CP-320626 CP 320626
	CP-320626 is an effective inhibitor of glycogen phosphorylase A (LGPA) in the human liver and GPA in the human muscle. Can act synergistically with glucose. It is a possible target for the treatment of type 2 diabetes.
T31672	Erythrofuranosyladenine 9-β-D-Erythrofuranosyladenine,ETA
	Erythrofuranosyladenine(9-beta-D-Erythrofuranosyladenine, ETA) is a nontoxic MTAP substrate. Erythrofuranosyladenine is an effective salvage agent for methylthioadenosine phosphorylase–selective therapy of T-cell acute lymphoblastic leukemia with L-alanos
T78379	9-Deazaguanine	Others	Others
	9-Deazaguanine，一种核苷类似物，有效抑制嘌呤核苷磷酸化酶（PNP）。
T11313	Forodesine hydrochloride BCX-1777 hydrochloride,Immucillin-H hydrochloride	Others	Others
	Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.
T35777	Nodularin
	The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatotoxic monocylic pentapeptide produced by the N. spumigena. It is a potent inhibitor of protein phosphatase types 1 (PP1) and 2A (PP2A), exhibiting IC50 values of 1.8 and 0.026 nM, respectively. PP2B is inhibited to a lesser extent with an IC50 of 1.8 μM. No apparent inhibitory eff...
T35416	α-D-Glucose-1-phosphate (sodium salt hydrate)
	α-D-Glucose-1-phosphate is an intermediate in glycogen metabolism.1,2It is a precursor in the biosynthesis of UDP-glucose, the glucose donor in glycogen biosynthesis.2α-D-Glucose-1-phosphate can be formed during glycogen breakdownviaphosphorolytic cleavage of glycogen by glycogen phosphorylase.1It can be converted to glucose-6-phosphate by phosphoglucomutase. α-D-Glucose-1-phosphate is combined with CTP by α-D-glucose-1-phosphate cytidylyltransferase to form CDP-glucose in the first step of CDP-...
T74046	D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine
	D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine，即1-磷酸核糖，作为核苷酸合成的关键中间体，在5-氟尿嘧啶(FUra)的磷酸化过程中，被尿苷磷酸化酶催化转化为核苷。
T35423	7-oxo Staurosporine
	7-oxo Staurosporine is an antibiotic originally isolated from S. platensis with diverse biological activites. It inhibits PKC, PKA, phosphorylase kinase, EGFR, and c-Src in vitro (IC50s = 9, 26, 5, 200, and 800 nM, respectively). 7-oxo Staurosporine induces cell cycle arrest in the G2/M phase in human leukemia K562 cells with a minimal effective dose (MED) of 30 ng/ml. It is cytotoxic to P388 mouse leukemia cells that are resistant and susceptible to doxorubicin . 7-oxo Staurosporine inhibits gr...
T83684	Myelin Basic Protein Peptide (mouse, bovine) TFA Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu,MBP Peptide
	Myelin基础蛋白(MBP)肽是PKC的肽底物，相比PKA、酪蛋白激酶1(CK1)、CK2、磷酸化酶激酶及钙/钙调蛋白依赖性蛋白激酶(CaMKII)，它对PKC有选择性。MBP肽已用于监测原发性人类肾动脉平滑肌细胞中的PKC活性。
T76306	Adipokinetic hormone I (Locusta migratoria)
	Adipokinetic hormone I (Locusta migratoria) (Lom-AKH-I) 是昆虫脂肪运动激素(AKH)类，可促进脂肪体内cAMP水平升高。AKH通过与AKH受体结合，并通过刺激性鸟嘌呤核苷酸结合蛋白(Gs)偶联，促进cAMP生成及糖原磷酸化酶活化，从而控制飞蝗动员脂肪体存储的碳水化合物和脂质。
T76304	Adipokinetic hormone II (Locusta migratoria)
	Adipokinetic hormone II (Locusta migratoria) (Lom-AKH-II)，一昆虫AKH，可提升脂肪体cAMP水平。AKHs通过其受体和Gs蛋白相互作用，增强cAMP生成与糖原磷酸化酶活性，从而直接调控飞蝗脂肪体中碳水化合物与脂质的动员。
T83805	Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium Rp-ADP-α-S
	Rp-Adenosine-5'-O-(1-thiodiphosphate)（Rp-ADP-α-S）是ADP-α-S的含硫异构体，是磷酸化酶激酶的抑制剂（Ki = 0.53 µM）。此化合物能诱导分离的人类血小板聚集（EC50 = 20 µM），并能引发经卡巴胆碱预收缩的豚鼠乙状结肠松弛（EC50 = 58.9 µM）。
T83806	Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium Sp-ADP-α-S
	Sp-Adenosine-5’-O-(1-thiodiphosphate) (Sp-ADP-α-S) 是硫含量核苷酸衍生物ADP-α-S的一种异构体。它是磷酸化酶激酶的抑制剂（Ki = 0.53 µM）。Sp-ADP-α-S能引起人类孤立血小板聚集（EC50 = 20 µM），并能使羧胺胆碱预收缩的豚鼠taenia coli松弛（EC50 = 58.9 µM）。

化合物

Phosphorylase Kinase β-Subunit Fragment (420-436)

Cat.No: TP1056

Synonym: Phosphorylase Kinase β-Subunit(420-436),Phosphorylase Kinase β-Subunit Fragment 420-436

Glycogen Phosphorylase Inhibitor

Cat.No: T37577

Sucrose phosphorylase

Cat.No: T76103

Maltose phosphorylase

Cat.No: T76100

Purine nucleoside phosphorylase

Cat.No: T76096

2'-Fluoro-2'-Deoxyadenosine

Cat.No: T9727

Target: Nucleoside Antimetabolite/Analog

D-galactosyl-β1-3-N-acetyl-D-hexosamine phosphorylase (BiGalHexNAcP)

Cat.No: T75401

Cat.No: T12399

Synonym: BCX 34

Target: Nucleoside Antimetabolite/Analog, HIV Protease

Cat.No: T14141

Target: Others, Methionine Adenosyltransferase (MAT)

UDP-sugar pyrophosphorylase (BlUSP)

Cat.No: T75398

Cat.No: T8493

Synonym: GPi 296,CP 368296

Target: Phosphorylase

Disodium monofluorophosphate

Cat.No: T0745

Synonym: Sodium Monofluorophosphate,单氟磷酸钠,NSC248

Target: Phosphatase, PKM, Phosphorylase

5-Iodotubercidin

Cat.No: T6745

Synonym: 5-碘代杀结核菌素,5-ITu,NSC 113939

Target: Adenosine Receptor

3'-Deoxyguanosine

Cat.No: T7782

Target: Others

Cat.No: TQ0008

Synonym: Methylthio-DADMe-Immucillin A,MTDIA

Target: Others

Cat.No: T15337

Synonym: 呋咯地辛,BCX-1777,Immucillin-H

Target: Others

Cat.No: T22683

Synonym: CP 316819,GPi 819

Target: Others

Cat.No: T10421

Target: Phosphorylase

Cat.No: T67822L

Synonym: BCX4208

Target: Endogenous Metabolite

Tipiracil hydrochloride

Cat.No: T2366

Synonym: MA-1 hydrochloride,盐酸替吡嘧啶

Target: Nucleoside Antimetabolite/Analog

Cat.No: T6455

Target: Phosphorylase

3'-Deoxy-3'-fluoroguanosine

Cat.No: TNU0091

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

Cat.No: T12908

Synonym: 5'-Deoxy-5'-isobutylthioadenosine,5'-Isobutylthioadenosine,5ˊ-异丁硫基-5ˊ-脱氧腺苷

Target: Nucleoside Antimetabolite/Analog, HSV

5-Fluorouridine

Cat.No: T1349

Target: Others, DNA/RNA Synthesis

Cat.No: T1600

Synonym: Ro 21-9738,AMC 0101,5'-DFUR,5-Fluoro-5'-deoxyuridine,去氧氟尿苷

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

CI 972 anhydrous

Cat.No: T14964

Synonym: CI 972 (anhydrous)

Target: Others

Cat.No: T22803

Target: Others

Cat.No: T68524

Cat.No: T70768

Cat.No: T70939

5-Aza-7-deazaguanine

Cat.No: T19148

Target: Others

7-Deaza-2’-deoxyadenosine

Cat.No: TNU1023

Maltoheptaose hydrate

Cat.No: T40410

Cat.No: T60343

N6-Methyladenosine 5'-monophosphate disodium salt

Cat.No: T12162

Target: Others

Benzylacyclouridine

Cat.No: T40932

Synonym: 5-Benzylacyclouridine,BAU

Antiangiogenic agent 2

Cat.No: T62931

Cat.No: T31048

Synonym: CP 320626

Erythrofuranosyladenine

Cat.No: T31672

Synonym: 9-β-D-Erythrofuranosyladenine,ETA

Cat.No: T78379

Target: Others

Forodesine hydrochloride

Cat.No: T11313

Synonym: BCX-1777 hydrochloride,Immucillin-H hydrochloride

Target: Others

Cat.No: T35777

α-D-Glucose-1-phosphate (sodium salt hydrate)

Cat.No: T35416

D-Ribofuranose1-dihydrogenphosphate dicyclohexanamine

Cat.No: T74046

7-oxo Staurosporine

Cat.No: T35423

Myelin Basic Protein Peptide (mouse, bovine) TFA

Cat.No: T83684

Synonym: Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu,MBP Peptide

Adipokinetic hormone I (Locusta migratoria)

Cat.No: T76306

Adipokinetic hormone II (Locusta migratoria)

Cat.No: T76304

Rp-Adenosine-5'-O-(1-thiodiphosphate) sodium

Cat.No: T83805

Synonym: Rp-ADP-α-S

Sp-Adenosine-5'-O-(1-thiodiphosphate) sodium

Cat.No: T83806

Synonym: Sp-ADP-α-S

Cat. No.	Product Name	Target	Signaling Pathways
T8155	Maltoheptaose	Phospholipase	Metabolism
	Maltoheptaose 是一种含有七个葡萄糖单元的麦芽低聚糖。它是一种磷酸化酶 B (phosphorylase B) 的活化剂，可用于 2-磷酸庚糖的制备。
T13539	Allopurinol riboside	Others; Endogenous Metabolite; Parasite; Drug Metabolite	Metabolism; Microbiology/Virology; Others
	Allopurinol riboside 是别嘌醇的代谢产物，具有抗寄生虫作用。 Allopurinol riboside 竞争性抑制嘌呤核苷磷酸化酶对肌苷的作用，Ki 为 277 μM。
T3S1850	Bayogenin	Others	Others
	Bayogenin 是紫花苜蓿皂苷，一定程度上能够抑制糖原磷酸化酶的活性。
T1709	2'-Deoxyinosine Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxyinosine (Guanine deoxyriboside) 具有抑制人癌细胞株生长的活性，并发现其与嘌呤核苷磷酸化酶缺乏有关。
TWP2911	Thymidine beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin	Others; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Thymidine (DThyd) 是一种细胞同步剂，是脱氧核糖核酸的特殊前体。它可在 DNA 复制前在 G1/S 边界阻滞细胞，是DNA 合成抑制因子。
T6680	Staurosporine Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素	Apoptosis; PKA; Antibacterial; Antibiotic; Src; PKC; Antifungal	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
	Staurosporine (AM-2282) 是一种蛋白激酶抑制剂，对 PKC、PKA、c-Fgr、Phosphorylase kinase 和 TAOK2 均有抑制活性 (IC50=6/15/2/3/3000 nM)，具有 ATP 竞争性和非选择性。Staurosporine 也可以诱导凋亡。
T4720	6-Hydroxypyridin-2(1H)-one hydrochloride 2,6-二羟基吡啶盐酸盐,2,6-Dihydroxypyridine hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	6-Hydroxypyridin-2(1H)-one hydrochloride (2,6-Dihydroxypyridine hydrochloride) 是内源性代谢产物的一种。
TN4188	Hederagonic acid	Others	Others
	Hederagonic acid ,arjunolic acid, bayogenin, and 4-epi-hederagonic acid show moderate potency of glycogen phosphorylase inhibition with IC50 of 53-103 uM.
T15636	K-252a Antibiotic K 252a,Antibiotic SF 2370,SF2370	Others	Others
	K-252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi. K-252a inhibits protein kinase (IC50: 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca2+/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively).
TN4584	Morolic acid	IL Receptor; COX; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro

天然产物

Cat.No: T8155

Target: Phospholipase

Allopurinol riboside

Cat.No: T13539

Target: Others, Endogenous Metabolite, Parasite, Drug Metabolite

Cat.No: T3S1850

Target: Others

2'-Deoxyinosine

Cat.No: T1709

Synonym: Guanine deoxyriboside,Deoxyinosine,2'-脱氧肌苷

Target: Others, Endogenous Metabolite

Cat.No: TWP2911

Synonym: beta-胸苷,5-Methyldeoxyuridine,Deoxyribothymidine,DThyd,NSC 21548,Thymidin

Target: Others, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T6680

Synonym: Antibiotic AM-2282,星形孢菌素,AM-2282,CGP 41251,星孢菌素

Target: Apoptosis, PKA, Antibacterial, Antibiotic, Src, PKC, Antifungal

6-Hydroxypyridin-2(1H)-one hydrochloride

Cat.No: T4720

Synonym: 2,6-二羟基吡啶盐酸盐,2,6-Dihydroxypyridine hydrochloride

Target: Others, Endogenous Metabolite

Hederagonic acid

Cat.No: TN4188

Target: Others

Cat.No: T15636

Synonym: Antibiotic K 252a,Antibiotic SF 2370,SF2370

Target: Others

Cat.No: TN4584

Target: IL Receptor, COX, HIV Protease

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