75
25
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3088 |
N-Ethylmaleimide
1-Ethyl-1H-pyrrole-2,5-dione,n-乙基马来酰亚胺,Ethylmaleimide,NEM |
Cysteine Protease; DUB | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination |
N-Ethylmaleimide (NEM) 是烷基化自由巯基的试剂, 是一种半胱氨酸蛋白酶抑制剂,用于实验生化研究。它也是一种去泛素化酶抑制剂,特异性抑制线粒体中的磷酸盐转运。 | |||
T68137 |
Sanfetrinem
GV104326 |
Antibiotic | Microbiology/Virology |
Sanfetrinem (GV104326) sodium 是一种新型可口服 β-内酰胺酶抗生素,对革兰氏阳性菌和革兰氏阴性菌显示出显著的抗菌活性,可用于研究细菌感染。 | |||
T9421 |
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
|
Others | Others |
5-(5-Fluoro-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid 为舒尼替尼杂质。 | |||
T1299 |
3-Pyridinemethanol
烟醇,Nicotinyl alcohol,Roniacol |
Others | Others |
3-Pyridinemethanol (Roniacol) 是一种具有降胆固醇作用的吡啶衍生物。 | |||
T80622 |
Trontinemab
|
||
Trontinemab为一种双特异性人源IgG1-κ抗体,靶向Aβ前体蛋白(APP)与转铁蛋白受体p90, CD71 (TFRC)。该抗体主要应用于阿兹海默症研究。 | |||
T22314 |
Doripenem
|
Antibacterial; Antibiotic | Microbiology/Virology |
Doripenem 是对革兰氏阳性菌、阴性菌和厌氧菌有效的β-内酰胺广谱抗生素。 | |||
T6411 |
Biapenem
CLI 86815,比阿培南,Biapenern,Omegacin,L 627,LJC 10627 |
Antibacterial; Antibiotic | Microbiology/Virology |
Biapenem (CLI 86815) 是不经肠道的广谱碳青霉烯抗生素。 | |||
T77392 |
Pepinemab
VX 15/2503 |
Others | Others |
Pepinemab(VX 15/2503) 是一种靶向信号素 4D 的 IgG4 人源化单克隆抗体。Pepinemab 具有抗癌活性,可阻断 SEMA4D 的活性,用于研究阿尔茨海默病类似的退行性疾病。 | |||
T77054 |
Lecanemab
BAN-2401 |
Beta Amyloid | Neuroscience |
Lecanemab (BAN-2401) 是一种靶向可溶性聚集性 β 淀粉样蛋白 (Abeta)的 IgG1 单克隆抗体,对寡聚体、原纤维和不溶性原纤维具有活性,可用于研究阿尔茨海默病 (AD) 引起的轻度认知障碍和轻度 AD 痴呆。 | |||
T11265 |
Faropenem daloxate
法罗培南酯,Faropenem medoxil |
Antibacterial; Antibiotic | Microbiology/Virology |
Faropenem daloxate (Faropenem medoxil) 是β-内酰胺类口服抗生素。 | |||
T124492 |
Imipenem
N-Formimidoyl thienamycin,MK0787 |
Antifungal | Microbiology/Virology |
Imipenem (MK0787) 是一种噻吩霉素衍生物,属于抗生素类,具有抗菌活性,对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。 | |||
T62839 |
Dalzanemdor
SAGE-718 |
NMDAR; iGluR | Membrane transporter/Ion channel; Neuroscience |
Dalzanemdor (SAGE-718) 是 NMDA 受体阳性变构调节剂,可用于研究亨廷顿舞蹈病、阿尔茨海默病和认知功能障碍。 | |||
T6231 |
Tebipenem Pivoxil
ME1211,Orapenem,替比培南匹酯 |
Antibacterial; Antibiotic | Microbiology/Virology |
Tebipenem Pivoxil (Orapenem) 是一种碳青霉烯类新型口服抗生素。 | |||
T1037 |
Doripenem monohydrate
多尼培南(一水合物),S 4661 monohydrate,Doripenem Hydrate,S-4661 |
Antibacterial; Antibiotic | Microbiology/Virology |
Doripenem monohydrate (S 4661 monohydrate) 是广谱β-内酰胺抗生素,它对革兰氏阳性,阴性和厌氧菌有抗菌作用。 | |||
T12004 |
Meropenem trihydrate
美罗培南三水合物,SM 7338 trihydrate |
Antibacterial; Antibiotic | Microbiology/Virology |
Meropenem trihydrate (SM 7338 trihydrate) 是一种碳青霉烯抗生素,具有广谱抗菌活性。它对敏感和耐药的杜克氏杆菌 (MIC 值为 0.015-0.12 mg/mL), 淋病奈瑟氏球菌 (MIC 值为 0.02-0.06 mg/mL)和流感嗜血杆菌 (MIC 值为 0.03-0.12 mg/mL) 具有活性。 | |||
TP1127L1 |
Nemifitide acetate(173240-15-8 free base)
INN 00835 acetate |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) 是一种合成的五肽抗抑郁药,具有快速起效的潜力。它是黑色素细胞抑制因子 (MIF) 的肽类似物。 | |||
T76861 |
Cinpanemab
BIIB054 |
Others | Others |
Cinpanemab (BIIB054) 是一种新型人源单克隆抗体,对 α-突触核蛋白 1-10 位残基具有亲和力。Cinpanemab 可用于研究帕金森及其相关疾病。 | |||
T76724 |
Nemolizumab
CIM331 |
Interleukin | Immunology/Inflammation |
Nemolizumab (CIM331) 是一种人源化的抗人白细胞介素-31 受体 a 单克隆抗体,对白细胞介素-31 (IL-31) 与其受体的结合和随后的信号转导有抑制作用。Nemolizumab 可用于研究特应性皮炎伴瘙痒。 | |||
T71012 |
Nemazoline Free Base
|
||
Nemazoline Free Base is a nasal decongestant. It has alpha 1-agonist/alpha 2-antagonist activity and was more effective and long-acting than oxymetazoline on canine nasal mucosa, in-vitro and in-vivo. Upon intranasal administration to dogs, the compound was devoid of systemic effects up to a concentration 1000 times that needed for local decongestant effect (1.65 micrograms, atomized from a 1 microgram mL-1 solution) suggesting limited mucosal absorption. After nasal administration to rats for 1... | |||
T4991 |
Ertapenem sodium
厄他培南钠,MK-826,L-749345,尔他培南钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ertapenem sodium (MK-826) 是碳青霉烯,是一种 β-内酰胺抗生素,具有广谱抗菌活性。 | |||
T4469 |
Nemorubicin
Methoxymorpholinyldoxorubicin,PNU-152243A,PNU 152243,奈莫柔比星 |
Others | Others |
Nemorubicin (PNU 152243) 是一种 Doxorubicin 衍生物,具有抗肿瘤活性。它需要完整的核苷酸切除修复系统才能发挥活性。它对多药耐药表型的多种肿瘤细胞系具有细胞毒性。 | |||
T12733 |
Rislenemdaz
CERC-301,MK-0657 |
iGluR | Membrane transporter/Ion channel; Neuroscience |
Rislenemdaz (CERC-301) (CERC-301)是 N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) 的拮抗剂。 | |||
T76726 |
Zagotenemab
LY33003560 |
Microtubule Associated | Cytoskeletal Signaling |
Zagotenemab 是一种人源化抗微管相关蛋白 tau 抗体,能选择性地调节大脑中的 tau 沉积物。Zagotenemab 可用于研究阿尔兹海默症等神经系统疾病。 | |||
T77053 |
Latozinemab
GSK-4527223,AL-001 |
Neurotensin Receptor | GPCR/G Protein |
Latozinemab (AL001) 是一种具有有效性和选择性的重组人源化针对 Sortilin 的单克隆抗体。Latozinemab 对 Sortilin具有很高的亲和力,可中断颗粒蛋白前体 (PGRN) 和 Sortilin 受体之间的相互作用。Latozinemab 可用于研究痴呆和阿尔兹海默症。 | |||
T15431 |
Nemiralisib
GSK2269557 (free base),GSK2269557 |
PI3K | PI3K/Akt/mTOR signaling |
Nemiralisib(GSK-2269557 free base)是一种可口服且具有有效性和特异性的 PI3Kδ 抑制剂,pKi 为 9.9。Nemiralisib 可用于治疗包括慢性阻塞性肺疾病在内的呼吸系统疾病。 | |||
T6715 |
Valnemulin hydrochloride
盐酸沃尼妙林,Valnemulin HCl |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Valnemulin hydrochloride (Valnemulin HCl) 是截短侧耳素抗生素,与 50s 核糖体亚基中的肽基转移酶结合来抑制细菌中的蛋白质合成。 | |||
T17021 |
Tebipenem
LJC 11036 |
Antibiotic | Microbiology/Virology |
Tebipenem 是一种口服碳青霉烯类抗生素。 它对革兰氏阳性和阴性细菌具有广谱活性。 | |||
T77092 |
Nadecnemab
REGN-5069 |
Others | Others |
Nadecnemab 是一种靶向胶质细胞源性神经营养因子家族受体 GFRA3 的 IgG4κ 抗体。Nadecnemab 可用于膝骨关节炎和神经系统疾病。 | |||
T16286 |
Nelonemdaz
Neu2000 |
Topoisomerase | DNA Damage/DNA Repair |
Neu2000 is an uncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptor. | |||
T77028 | Gosuranemab | ||
Gosuranemab (BMS-986168) 是一种人源化 IgG4抗tau 单克隆抗体。Gosuranemab 与人 N 端 tau 残基 15-22 结合。Gosuranemab 具有用于阿尔茨海默病 (AD) 研究的潜力。 | |||
T80900 |
Unasnemab
MT-3921,rH116A3 |
||
Unasnemab (MT-3921),一种人源化IgG1单克隆抗体,与排斥引导分子A (RGMa) 结合,用以改善运动功能及促进神经再生,适用于脊髓损伤研究。 | |||
T124832 |
Gnemonol B
|
||
T66294 |
Protected meropenem
|
||
Protected meropenem 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66294,CAS号为 96036-02-1。 | |||
T73668 |
Sanfetrinem sodium
|
||
Sanfetrinem (GV104326) sodium,作为一种β-内酰胺酶稳定的抗生素(antibiotic),对革兰氏阳性菌和革兰氏阴性菌展现出广泛的抗菌活性。 | |||
T38458 |
Faropenem
|
||
Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory... | |||
T22433 |
Sulopenem
CP-70429,硫培南 |
Others | Others |
Sulopenem, an orally active, potent inhibitor of beta-lactamase, is a parenteral penem antibiotic with broad-spectrum activities against Gram-negative and Gram-positive bacteria. | |||
T4991L |
Ertapenem (sodium salt)
|
||
Ertapenem (sodium salt) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T4991L,CAS号为 153832-38-3。 | |||
T74821 |
Nemonoxacin
|
||
Nemonoxacin (TG-873870) 是一种口服有效的广谱抗生素,对多种葡萄球菌、链球菌、肠球菌、淋病奈瑟菌和流感嗜血杆菌显示出强效的抑制活性。适用于研究细菌感染和社区获得性肺炎。 | |||
T28992 | Tomopenem | ||
Tomopenem is a penem antibiotic. | |||
T71467 | Nemorubicin HCL | ||
Nemorubicin HCL is the salt form of Nemorubicin, also known as PNU152243A, a doxorubicin derivative that differs significantly from its parent drug in terms of spectrum of antitumor activity, metabolism and toxicity profile. The drug is active on tumors resistant to alkylating agents, topoisomerase II inhibitors and platinum derivatives. It works primarily through topoisomerase I inhibition. Of note, Nemorubicin is active in cells with upregulation of the nucleotide excision repair (NER) pathway... | |||
T28154 |
Nemonoxacin Malate
TG-873870,TG873870,TG 873870 |
||
Nemonoxacin is a non-fluorinated quinolone antibiotic. | |||
T67354 | 3,5-Dimethyl-4-methoxy-2-pyridinemethanol | ||
3,5-Dimethyl-4-methoxy-2-pyridinemethanol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67354,CAS号为 86604-78-6。 | |||
T76725 | Tilavonemab | ||
Tilavonemab (ABBV-8E12) 是一种人源化抗 tau 抗体,结合 tau 蛋白 N 端附近的 25-30 位氨基酸。Tilavonemab 阻断人和小鼠神经元摄取 tau 聚集体的能力,并能减少脑萎缩。Tilavonemab 可用于阿尔兹海默症的研究。 | |||
T76949 | Zelminemab | ||
Zelminemab (AMG-301) 是一种人单克隆抗体,可抑制 I 型 PACAP (PAC1) 受体。 | |||
TP1127 |
Nemifitide diTFA
INN 00835 diTFA |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Nemifitide diTFA (INN 00835 diTFA) 是一种合成的五肽,是一种可透过血脑屏障的黑色素细胞抑制因子 (MIF) 的肽类似物,具有有效的抗抑郁活性。 | |||
T80616 |
Posdinemab
|
||
Posdinemab为一种针对微管相关蛋白tau (MAPT)的人源化IgG1κ抗体。 | |||
T35729 |
Nemadipine-A
|
||
Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel α1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick ciliary neurons. Nemadipine A increases TRAIL-induced cytotoxicity and synergistically enhances caspase-8 and caspase-3 activation in a concentration-dependent manner in H1299 lung adenocarcinoma cells. It ... | |||
T27813 |
Lenapenem
carbapenem |
||
Lenapenem is a broad-spectrum, carbapenem antibiotic with bactericidal activity by weakens the bacterial cell wall and leads to lytic cell death. | |||
T67005 |
3-Thiophenemalonic Acid
|
||
3-Thiophenemalonic Acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67005,CAS号为 21080-92-2。 | |||
T33627 |
Nematocyphol
|
||
Nematocyphol is a triterpenoid from Euphorbia nematocypha hand-mazz. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TQ0036 |
Anemarrhenasaponin I
|
Others | Others |
Anemarrhenasaponin I 是一种对血小板聚集有显著的抑制作用的传统中药。 | |||
T8504 |
Dianemycin
Nanchangmycin (free acid) |
Antibacterial; Antibiotic | Microbiology/Virology |
Dianemycin (Nanchangmycin (free acid)) 由Streptomyces nanchangensis 产生的一种聚醚抗生素,抑制革兰氏阳性菌。它也是一种针对 Zika 病毒的广谱抗病毒药物。 | |||
TN6931 |
Anemarrhenasaponin Ia
知母皂苷IA,(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan |
Others | Others |
Anemarrhenasaponin Ia ((2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5R,6R)-4,5-dihydroxy-2-{[(1R,3R,4R,7S,9S,12S,13S,16S,18R)-3-hydroxy-6-methoxy-7,9,13-trimethyl-6-(3-methylbutyl)-5-oxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosan-16-yl]oxy}-6-(hydroxymethyl)oxan-3-yl]oxy}-6-(hydroxymethyl)oxan) 具有抗炎活性。Anemarrhenasaponin Ia 具有抗炎作用,从知母根茎中分离得到。 Anemarrhenasaponin Ia 抑制 N-甲酰-甲硫氨酰-亮氨酰-苯丙氨酸 (fMLP) 诱导的超氧化物的进一步产生。 | |||
T0224 |
Meropenem
美罗培南,SM 7338 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Meropenem (SM 7338) 是一种具有广谱抗菌活性的碳青霉烯抗生素,对敏感和耐药的淋病奈瑟氏球菌,流感嗜血杆菌和杜克氏杆菌的 MIC 值分别为 0.02-0.06 mg/mL,0.03-0.12 mg/mL 和 0.015-0.12 mg/mL。 | |||
T5743 |
Gymnemagenin
|
Liver X Receptor | Metabolism |
Gymnemagenin 是一种分离自G. sylvestre 的三萜。 它具有抗病毒作用,对糖尿病和肥胖症具有潜在的研究价值。 | |||
T7030 |
anemarsaponin B
知母皂苷B,知母皂苷 B |
p38 MAPK; NF-κB; MEK; COX; NO Synthase | Immunology/Inflammation; MAPK; Neuroscience; NF-κB |
Anemarsaponin B 是一种甾体皂苷,可降低iNOS 和COX-2的蛋白和 mRNA 水平,减少促炎细胞因子的表达和产生。它通过阻断 IκBα 的磷酸化来抑制NF-κB 的 p65 亚基的核转位,还抑制 MAP 激酶激酶 3/6 (MKK3/6) 和混合谱系激酶 3 的磷酸化。 | |||
T5041 |
Faropenem sodium
法罗培南,法罗培南钠 |
Antibacterial; Antibiotic | Microbiology/Virology |
Faropenem sodium 是一种口服生物可利用的青霉烯类抗生素,能有效杀灭结核分枝杆菌,治疗结核病和社区获得性肺炎。 | |||
T1505 |
Imipenem monohydrate
N-Formimidoyl thienamycin monohydrate,亚胺培南,Imipenem,亚胺培南一水物 |
Antibacterial; Antibiotic | Microbiology/Virology |
Imipenem monohydrate (Imipenem) 是从微生物 Streptomyces cattleya 分离得到的碳青霉烯类抗生素,是一种用于静脉注射的β 内酰胺类抗生素,作用于细菌细胞壁,能广泛有效抑制多种革兰氏阳性和阴性菌。 | |||
T70495 | Scytonemin | ||
Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive one to scytonemin. Scytonemin , representing a novel Plk1 inhibitor, ... | |||
TN4630 | Nemoralisin | Others | Others |
Nemoralisin exhibits weak cytotoxicities (IC50>10 uM) against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
TN1382 | Anemarrhenasaponin III | Others | Others |
Anemarrhenasaponin III is a natural product | |||
TN4629 |
Nemoralisin C
|
Others | Others |
Nemoralisin C shows antiproliferative activity against HepG2, AGS, MCF-7, and A-549 cancer cell lines. | |||
TMA0053 |
Anemonin
|
Others | Others |
Anemonin 是来自 Pulsatilla chinensis Regel 的天然产物。 | |||
TN4631 |
Nemorensine
|
Others | Others |
Nemorensine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4631,CAS号为 50906-96-2。 | |||
T82249 | Gymnemanol | ||
Gymnemanol为一三萜类化合物,源自匙羹藤(Gymnema sylvestre)的提取。 | |||
T67143 |
1-Naphthalenemethanol
|
||
1-Naphthalenemethanol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T67143,CAS号为 4780-79-4。 | |||
T36954 |
Nemorosone
|
||
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem... | |||
TN2420 |
Protoanemonin
|
Antibacterial | Microbiology/Virology |
Protoanemonin is a naturally occurring compound which may be isolated from plants of the family Ranunculaceae. Protoanemonin can also be produced by Pseudomonas sp. | |||
T30048 |
Anemonin (6CI)
Pulsatilla camphor,Anemonin,Anemone camphor |
||
Anemonin is a furanone dimer found in the Buttercup (Ranunculaceae) family. Anemonin has been shown to regulate tyrosinase-related proteins and mRNA in human melanocytes and may be useful in attenuting osteoarthritis progression. | |||
TN1152 |
Anemarsaponin E
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Others | Others |
Anemarsaponin E is a nartural product from salt Anemarrhenae Rhizoma. | |||
TN6592 | Isonemerosin | ||
Isonemerosin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6592,CAS号为 181524-79-8。 | |||
TN1718 |
Gymnemic acid I
(+)-Gymnemic acid I,Gymnemic acid I, (+)-,匙羹藤酸 I |
Others | Others |
Gymnemic acid I (Gymnemic acid I, (+)-) 抑制蛋白质生物合成,具有抗甜的作用。 | |||
TN1221 |
21-O-Tigloylgymnemagenin
21-O-顺芷酰基匙羹藤新苷元,(3BETA,4ALPHA,16BETA,21BETA,22ALPHA)-齐墩果-12-烯-3,16,21,22,23,28-六醇 21-[(2E)-2-甲基-2-丁烯酸酯],21-O-Tigloylgymnemagenin |
Others | Others |
21-O-Tigloylgymnemagenin is a natural product | |||
TN7001 |
5-Azulenemethanol,1,2,3,3a,4,5,6,7-octahydro-.alpha.,.alpha.,3,8-tetramethyl-,[3S-
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5-Azulenemethanol,1,2,3,3a,4,5,6,7-octahydro-.alpha.,.alpha.,3,8-tetramethyl-,[3S- is a natural product. | |||
TN3413 |
Anemarrhena B
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Others | Others |
Anemarrhena B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3413,CAS号为 1627521-95-2。 |