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Targets Recommended: Others

10

抑制剂 & 化合物

1751

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T12555 PROTAC FLT-3 degrader 1

Others Others
PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.
T72407 c-Met/MEK1/Flt-3-IN-1

Antiproliferative against-3 具有良好的抗癌细胞增殖活性,对 Hela、A549 和 MCF-7 的细胞的 IC50值分别为 0.21 µM、0.39 µM 和 0.33 µM。Antiproliferative against-3 (comp 33) 剂量依赖性的诱导 A549 细胞的凋亡,并将细胞阻滞在 G1 期。
T6720 Vatalanib dihydrochloride

CGP-797870 dihydrochloride,ZK-222584 dihydrochloride,Vatalanib 2HCl,PTK787 dihydrochloride,Vatalanib (PTK787) 2HCl,CGP-79787 dihydrochloride,瓦他拉尼

Apoptosis; VEGFR; PDGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Vatalanib dihydrochloride (PTK787 dihydrochloride) 是一种VEGFR2/KDR 的抑制剂,其IC50值为37nM。
T5466 Tyrosine kinase-IN-1

VEGFR; FGFR; FLT; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Tyrosine kinase-IN-1是一种多靶点酪氨酸激酶抑制剂,能够抑制KDR (IC50:4 nM),Flt-1 (IC50:20 nM),FGFR1 (IC50:4 nM) 和 PDGFRα (IC50:2 nM)。
T2624 OSI-930

OSI 930,噻尔非尼

Apoptosis; c-Fms; Raf; VEGFR; FLT; CSF-1R; Src; c-Kit Angiogenesis; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
OSI-930 是 Kit,KDR 和 CSF-1R (c-Fms)的口服选择性抑制剂,IC50分别为 80 nM,9 nM 和 15 nM。它具有抗肿瘤活性,靶向肿瘤中的癌细胞增殖和血管生成。它还适度抑制 Flt-1,c-Raf 和 Lck,并且对 PDGFRα/β,Flt-3和 Abl 具有较弱的抑制活性。
T2514 Linifanib

利尼伐尼,ABT-869,RG3635,AL-39324

Apoptosis; c-Fms; VEGFR; FLT; CSF-1R; PDGFR; c-Kit; Autophagy Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
Linifanib (AL-39324) 是一种高效口服的VEGFR 和PDGFR 家族多靶点抑制剂,具有显著的抗肿瘤活性。它对无关 RTKs、可溶性酪氨酸激酶或丝氨酸/苏氨酸激酶的活性要低得多。它是特异性 miR-10b 抑制剂,阻断miR-10b 的生物合成。
T6184 Orantinib

SU6668,TSU-68,NSC 702827

Apoptosis; VEGFR; FGFR; PDGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Orantinib (NSC 702827) 是一种多靶点受体酪氨酸激酶抑制剂,对 Flt-1、PDGFRβ和FGFR1的Ki 值分别为 2.1 μM、8 nM 和 1.2 μM。
T39818 Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH

Desmorpholinyl Quizartinib-PEG2-COOH is a compound featuring an FLT-3 ligand and a PEG-based PROTAC linker. It is employed in the synthesis of PROTAC FLT-3 degrader 1, which serves as a degrader for the FLT-3 internal tandem duplication (ITD) through PROTAC technology. The degrader exhibits an IC50 of 0.6 nM.
T68039 cep-5214

CEP-5214是一种有效的、低纳摩尔的人 VEGF-R 酪氨酸激酶泛抑制剂,对 VEGF-R1/FLT-1、VEGF-R2/KDR 和VEGF-R3/FLT-4的IC50分别为16、8和4 nM,细胞活性与分离的酶活性相当。
T79420 FLT3-IN-22

FLT3-IN-22(化合物22f)是一款高效的FLT3抑制剂,具有针对FLT3和FLT3/D835Y极低的IC50值,分别为0.941 nM和0.199 nM。在MV4-11细胞和携带FLT3变异的Ba/F3细胞系中(涵盖FLT3-D835Y及FLT3-F691L),此抑制剂显示出显著的抗增殖能力。

化合物

PROTAC FLT-3 degrader 1
Cat.No: T12555
Synonym:
Target: Others
c-Met/MEK1/Flt-3-IN-1
Cat.No: T72407
Synonym:
Target:
Vatalanib dihydrochloride
Cat.No: T6720
Synonym: CGP-797870 dihydrochloride,ZK-222584 dihydrochloride,Vatalanib 2HCl,PTK787 dihydrochloride,Vatalanib (PTK787) 2HCl,CGP-79787 dihydrochloride,瓦他拉尼
Target: Apoptosis, VEGFR, PDGFR
Tyrosine kinase-IN-1
Cat.No: T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
OSI-930
Cat.No: T2624
Synonym: OSI 930,噻尔非尼
Target: Apoptosis, c-Fms, Raf, VEGFR, FLT, CSF-1R, Src, c-Kit
Linifanib
Cat.No: T2514
Synonym: 利尼伐尼,ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
Orantinib
Cat.No: T6184
Synonym: SU6668,TSU-68,NSC 702827
Target: Apoptosis, VEGFR, FGFR, PDGFR
Desmorpholinyl Quizartinib-PEG2-COOH
Cat.No: T39818
Synonym: Desmorpholinyl Quizartinib-PEG2-COOH
Target:
cep-5214
Cat.No: T68039
Synonym:
Target:
FLT3-IN-22
Cat.No: T79420
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1,Vascu...

Human Human Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPY-00637 FLT1 Protein, Human, Recombinant (aa 1-328, His)

VEGFR-1,fms-related tyrosine kinase 1,VEGF...

Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPK-00451 VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated

FLT,Flt-1,FRT,VEGFR1,VEG...

Human HEK293
VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May pla...
TMPK-00450 VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)

FLT1,FRT,FLT,Flt-1

Human HEK293
VEGFR1 (vascular endothelial growth factor receptor 1), also called Flt-1 (Fms-like tyrosine kinase), is a 180 kDa type I transmembrane glycoprotein in the class III subfamily of receptor tyrosine kinases (RTKs).yrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. May pla...
TMPY-01011 FGFR1 Protein, Human, Recombinant (His)

KAL2,FLT2,FGFBR,HRTFDS,OGD,FLG,HBGFR,bFGF-R-1

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)

FGFR-1,FLG,CD331,HH2,FLT2,KAL2,FG...

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-06034 FGFR1 Protein, Human, Recombinant (beta (IIIb), His)

FLG,CD331,N-SAM,HBGFR,HRTFDS,BFGFR,OGD,KAL2,fibrobl...

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-00119 FLT1 Protein, Human, Recombinant (hFc)

VEGFR1,VEGFR-1,fms-related tyrosine kinase...

Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPY-06780 FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated

FLT,fms-related tyrosine kinase 1,VEGFR

Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPY-02108 FLT1 Protein, Human, Recombinant (aa 1-756, His)

FLT-1,VEGFR1,fms-related tyrosine...

Human HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPK-00523 FLT3 Protein, Cynomolgus, Recombinant (hFc)

FLT-3,FLK2,STK-1,CD135

Cynomolgus HEK293
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 ...
TMPK-00416 FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated

STK-1,FLK2,CD135,FLT-3

Human CHO
The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 ...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)

CD331,FGFR-1,FLT-2,BFGFR,N-sam,FG...

Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment.
TMPY-05733 FLT1 Protein, Mouse, Recombinant (His)

Flt-1,VEGFR1,VEGFR-1,fms...

Mouse HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR1 β (IIIc),N-sam,FLT-2,BFGFR,bFGF-R-

Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment.
TMPY-06665 FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated

VEGFR1,sFlt1,AI323757,VEGFR-1...

Mouse HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPY-01782 FGFR1 Protein, Mouse, Recombinant (hFc)

Hspy,fibroblast growth factor receptor 1,bFGF-R-

Mouse HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-01781 FGFR1 Protein, Mouse, Recombinant (His)

Flt-2,FLG,fibroblast growth factor receptor 1

Mouse HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-04371 FGFR1 Protein, Human, Recombinant (His & GST)

HRTFDS,CEK,OGD,FLG,FLT2,FGFBR,bFGF-R-1,N-S...

Human Baculovirus-Insect Cells
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)

KAL2,OGD,N-SAM,CEK,FLT2,HH2,FLG,CD331,BFGF...

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-05761 FGFR1 Protein, Human, Recombinant (His), Biotinylated

FLT-2,KAL2,FGFBR,HRTFDS,BFGFR,fibroblast growth fac...

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-05777 FGFR1 Protein, Human, Recombinant (hFc)

N-SAM,OGD,HH2,HBGFR,FLT2,CEK,FLG,FGFR-1,FG...

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-06033 FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)

HBGFR,BFGFR,bFGF-R-1,FLG,FGFR-1,fibroblast...

Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. Fibroblast growth factors (FGFs) (FGF1 - 10 and 16 - 23) are mitogenic signaling molecules that have roles in angiogenesis, wound healing, cell migration, neural outgrowth and embryonic development. FGFs bind heparan sulfate glyc...
TMPY-01936 VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

Flt-4,VEGFR-3,Chy,fms related tyrosine kinase 4,VEG...

Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR...
TMPY-01937 VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)

VEGFR-3,fms related tyrosine kinase 4,VEGFR3,Flt-4,...

Mouse HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR...
TMPY-01069 VEGFR3/FLT4 Protein, Human, Recombinant (hFc)

FLT41,fms related tyrosine kinase 4,VEGF R...

Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR...
TMPY-06620 VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated

PCL,VEGFR-3,LMPH1A,fms related tyrosine kinase 4,

Human HEK293
Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). The VEGFR3 protein is expressed mainly on lymphatic vessels but it is also up-regulated in tumor angiogenesis. Mutations in VEGFR3 have been identified in patients with primary lymphoedema. The VEGF-C/VEGF-D/VEGFR...
TMPY-03299 FLT1 Protein, Rat, Recombinant (His)

fms-related tyrosine kinase 1

Rat HEK293
Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / F...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

AMPK, AMPK(α1, β1, γ1)

Human Baculovirus-Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...

Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-00664 ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

Angiopoietin-2,AGPT2,angiopoietin 2,ANG2

Human HEK293
Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine kinase receptor, Tie-2, found primarily on the luminal surface of endothelial cells. ANG-2's role in angiogenesis generally is considered as an antagonist for ANG1, inhibiting ANG1-promoted Tie2 signaling, which is critical for blood vessel maturation and stabilization. ANG-2 mod...
TMPY-01298 CADM1 Protein, Human, Recombinant (His)

Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC-

Human HEK293
Members of the immunoglobulin superfamily often play key roles in intercellular adhesion. IGSF4 is a novel immunoglobulin (Ig)-like intercellular adhesion molecule. Three Ig-like domains are included in the extracellular domain of IGSF4 and mediate homophilic or heterophilic interactions independently of Ca2+. The cytoplasmic domain of IGSF4 contains the binding motifs that connect to actin fibers. Since IGSF4 has been characterized by several independent research groups, this molecule is called...
TMPY-04779 BTN3A2 Protein, Human, Recombinant (His)

BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...

Human HEK293
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted...
TMPY-03363 C-Reactive Protein Protein, Human, Recombinant

C-Reactive Protein,C-reactive protein, pentraxin-related,PTX...

Human HEK293
C-reactive protein (CRP) is synthesized by the liver in response to factors released by fat cells. It is a member of the pentraxin family of proteins. The levels of CRP rise in response to inflammation. Human C-reactive protein (CRP) is the classical acute phase reactant, the circulating concentration of which rises rapidly and extensively in a cytokine-mediated response to tissue injury, infection and inflammation. Serum CRP values are routinely measured, empirically, to detect and monit...
TMPY-02512 Alpha-Synuclein Protein, Human, Recombinant

PD1,α-Synuclein,PARK4,synuclein, α (non A4 componen...

Human E. coli
Alpha-Synuclein (alpha-Syn), also known as NACP or SNCA, exists as at least two structural isoforms: one is helix-rich, membrane-bound form that both the N- and C-terminal regions of alpha-synuclein are tightly associated with membranes and the other is disordered, cytosolic form. Synuclein is found predominantly in the presynaptic termini, in both free or membrane-bound forms. SNCA is extensively localized in nucleus of neurons. It has been shown that alpha-Synuclein was highly expressed in the...
TMPY-05354 CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD28 molecule,Tp44

Human HEK293
CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell r...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc)

1810061I13Rik,Clec2,C-ty...

Mouse HEK293
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and...
TMPY-04824 CTLA-4 Protein, Human, Recombinant

CTLA-4,GSE,IDDM12,CELIAC3,ALPS5,CD,GRD4,cytotoxic T...

Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role i...
TMPY-00986 IL-34 Protein, Mouse, Recombinant (His)

interleukin 34,2010004A03Rik,AI593503

Mouse HEK293
IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colon...
TMPY-03273 IL-18 Protein, Mouse, Recombinant

interleukin 18,白细胞介素,白介素,Il-18,Igif

Mouse E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its bi...
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)

p60,TNFR60,TNFAR,TBP1,CD120a,TNFR1

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD prot...
TMPY-02617 Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)

NP Protein

H2N2 Baculovirus-Insect Cells
Influenza viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. Nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral prot...
TMPY-01573 SIRP alpha Protein, Human, Recombinant (G75A, His)

PTPNS1,signal-regulatory protein alpha,SIRP,MYD-

Human HEK293
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antigen-like family member A, SIRPA and CD172a, is a single-pass type I membrane protein which contains two Ig-like C1-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIRPA is ubiquitously expressed. It is highly expressed in brain and detected ...
TMPY-02412 ENO1 Protein, Human, Recombinant (His)

PPH,NNE,enolase 1, (alpha),ENO1L1...

Human E. coli
The ENO1 gene encodes a multifunctional enzyme that has been identified as a key component of the glycolytic pathway. ENO1 overexpression and post-translational modifications could be of diagnostic and prognostic value in many cancer types. The results of the ENO1 expression profiling of ovarian follicles suggest that ENO1 may play an important dual role in the progress of follicular development, where ENO1 acts as a glycolytic enzyme and also mediates apoptosis. ENO1 overexpression could make ...
TMPY-01055 IL-4R Protein, Human, Recombinant (His)

interleukin 4 receptor,IL4RA,IL4R,CD124,IL-4RA

Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins ...
TMPY-01912 Cadherin 17/CDH17 Protein, Human, Recombinant (His)

HPT-1,cadherin 17, LI cadherin (liver-inte...

Human HEK293
Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region, 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of ...
TMPY-01834 CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)

CD16,Fc receptor, IgG, low affinity III

Mouse HEK293
Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as...
TMPY-01608 Decorin Protein, Human, Recombinant (His)

PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII

Human HEK293
Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core protein and a covalently linked glycosaminoglycan chain which is either chondroitin sulfate (CS) or dermatan sulfate (DS). As a component of connective tissue, decorin interacts with several extracellular matrix components, such as type I collagen and fibronectin, and plays a role...
TMPY-04810 CD47 Protein, Mouse, Recombinant (His)

AA407862,CD47 molecule,AW108519,91

Mouse HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),FR-BETA,F...

Human HEK293
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
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重组蛋白

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: Human Cells
FLT1 Protein, Human, Recombinant (aa 1-328, His)
Cat.No: TMPY-00637
Species: Human
Expression System: HEK293
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00451
Species: Human
Expression System: HEK293
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00450
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01011
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
Cat.No: TMPY-06036
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
Cat.No: TMPY-06034
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00119
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06780
Species: Human
Expression System: HEK293
FLT1 Protein, Human, Recombinant (aa 1-756, His)
Cat.No: TMPY-02108
Species: Human
Expression System: HEK293
FLT3 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPK-00523
Species: Cynomolgus
Expression System: HEK293
FLT3 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00416
Species: Human
Expression System: CHO
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00392
Species: Human
Expression System: HEK293
FLT1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05733
Species: Mouse
Expression System: HEK293
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00394
Species: Human
Expression System: HEK293
FLT1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06665
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01782
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01781
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04371
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
Cat.No: TMPY-06035
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05761
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05777
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
Cat.No: TMPY-06033
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01936
Species: Mouse
Expression System: HEK293
VEGFR3/FLT4 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01937
Species: Mouse
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01069
Species: Human
Expression System: HEK293
VEGFR3/FLT4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06620
Species: Human
Expression System: HEK293
FLT1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03299
Species: Rat
Expression System: HEK293
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-03745
Species: Human
Expression System: HEK293
ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00664
Species: Human
Expression System: HEK293
CADM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01298
Species: Human
Expression System: HEK293
BTN3A2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04779
Species: Human
Expression System: HEK293
C-Reactive Protein Protein, Human, Recombinant
Cat.No: TMPY-03363
Species: Human
Expression System: HEK293
Alpha-Synuclein Protein, Human, Recombinant
Cat.No: TMPY-02512
Species: Human
Expression System: E. coli
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05354
Species: Human
Expression System: HEK293
CLEC-2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00586
Species: Mouse
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant
Cat.No: TMPY-04824
Species: Human
Expression System: HEK293
IL-34 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00986
Species: Mouse
Expression System: HEK293
IL-18 Protein, Mouse, Recombinant
Cat.No: TMPY-03273
Species: Mouse
Expression System: E. coli
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
Cat.No: TMPY-01459
Species: Human
Expression System: HEK293
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)
Cat.No: TMPY-02617
Species: H2N2
Expression System: Baculovirus-Insect Cells
SIRP alpha Protein, Human, Recombinant (G75A, His)
Cat.No: TMPY-01573
Species: Human
Expression System: HEK293
ENO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02412
Species: Human
Expression System: E. coli
IL-4R Protein, Human, Recombinant (His)
Cat.No: TMPY-01055
Species: Human
Expression System: HEK293
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
Cat.No: TMPY-01912
Species: Human
Expression System: HEK293
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
Cat.No: TMPY-01834
Species: Mouse
Expression System: HEK293
Decorin Protein, Human, Recombinant (His)
Cat.No: TMPY-01608
Species: Human
Expression System: HEK293
CD47 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04810
Species: Mouse
Expression System: HEK293
FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293
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