219
11
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Cat. No. | Product Name | ||
---|---|---|---|
L6120 | 黄酮类天然产物库 | 514 compounds | |
514 种黄酮类天然产物的独特集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T18466 |
N3-C3-NHS ester
叠氮-C3-琥珀酰亚胺酯 |
Others | Others |
N3-C3-NHS ester 是一种不可切割的 ADC 接头,用于合成抗体-药物偶联物。 | |||
T12935 |
SMN-C3
MV8T2MCK57 |
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
SMN-C3 (MV8T2MCK57) 是口服有效的 SMN2 剪接调节剂。SMN-C3可用于脊椎肌肉萎缩 (SMA) 的研究。 | |||
T9643 |
ZN-c3
|
Wee1 | Cell Cycle/Checkpoint |
ZN-c3 是一种有效的选择性 Wee1 抑制剂,具有平衡的效力、ADME 和药代动力学特性。 | |||
T40000 |
Pomalidomide-C3-I
|
Others | Others |
Pomalidomide-C3-I 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。 | |||
T40011 |
Thalidomide-CH2CONH-C3-COOH
|
Others | Others |
Thalidomide-CH2CONH-C3-COOH 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于Thalidomide 的CRBN 配体和接头。 | |||
T40002 |
Pomalidomide-C3-NH2 hydrochloride
|
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
Pomalidomide-C3-NH2 hydrochloride 包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker,是合成的 E3 连接酶配体-linker 偶联物,可用于 PROTAC 的合成。 | |||
T9282 |
DBCO-C3-Acid
DBCO-ACID |
Others | Others |
DBCO-(CH2)3-Acid 是一种用于抗体-药物偶联物的 Click Chemistry 中间体,可用以合成 ADC linker。 | |||
T41163 |
ZNL 02-096
Pomalidomide-C3-adavosertib |
Apoptosis; Wee1 | Apoptosis; Cell Cycle/Checkpoint |
ZNL 02-096 (Pomalidomide-C3-adavosertib) 是一种快速和选择性的 Wee1 降解剂 (IC50=3.58 nM)。ZNL 02-096 可在亚摩尔浓度下选择性降解 Wee1,而不损伤 AZD 1775 的二级靶点 PLK1。在体外 MOLT-4 细胞中,ZNL 02-096 可诱导 Wee1 降解、DNA 损伤积累、细胞周期停滞在 G2/M 期和细胞凋亡。ZNL 02-096 在 300 种癌症细胞系中显示出抗增殖作用。 | |||
T4648 |
TC-G-1008
GPR39-C3 |
GHSR | GPCR/G Protein |
TC-G-1008 (GPR39-C3) 是一种口服有活性的 GPR39激动剂,可作用于大鼠受体(EC50: 0.4 nM)和人类受体(EC50:0.8 nM)的。 | |||
T18794 |
Tetrazine-Ph-NHCO-C3-NHS ester
|
Others; PROTAC Linker | Others; PROTAC |
Tetrazine-Ph-NHCO-C3-NHS ester是一种源于PEG的PROTACs合成连接剂。 | |||
T38591 |
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA)
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) |
||
Biotinyl-NH-PEG3-C3-amido-C3-COOH (DIPEA) is a polyethylene glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker, utilized for synthesizing PROTACs. | |||
T40162 |
Acid-C3-SSPy
Acid-C3-SSPy |
||
Acid-C3-SSPy is a cleavable DBA-DM4 linker used in the synthesis of DBA-DM4 , a drug-linker conjugate for ADC. | |||
T39637 |
Pomalidomide-amido-C3-COOH
Pomalidomide-amido-C3-COOH |
||
Pomalidomide-amido-C3-COOH is a conjugate compound synthesized as an E3 ligase ligand-linker. It combines a cereblon ligand derived from Pomalidomide with a linker, both of which are used in PROTAC technology. | |||
T39642 |
Thalidomide-O-C3-acid
Thalidomide-O-C3-acid |
||
Thalidomide-O-C3-acid is a chemically derived conjugate that combines a cereblon ligand based on Thalidomide and a linker commonly employed in PROTAC technology. This synthesized E3 ligase ligand-linker conjugate serves to facilitate targeted protein degradation. | |||
T40574 |
Br-C3-methyl ester
Br-C3-methyl ester |
||
Br-C3-methyl ester is an alkyl/ether-based PROTAC linker utilized for the synthesis of PROTAC PD-1/PD-L1 degrader-1. | |||
T38549 |
Azido-C1-PEG3-C3-NH2
Azido-C1-PEG3-C3-NH2 |
||
Azido-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T41129 |
Bis-SS-C3-NHS ester
Bis-SS-C3-NHS ester |
||
Bis-SS-C3-NHS ester is a cleavable linker compound employed in ADC synthesis. It finds application in the construction of antibody-drug conjugates (ADCs). | |||
T39894 |
Thalidomide-4-C3-NH2 hydrochloride
Thalidomide-4-C3-NH2 hydrochloride |
||
Thalidomide-4-C3-NH2 hydrochloride is a Thalidomide-derived cereblon ligand utilized for the recruitment of CRBN protein. This compound can be linked to the ligand for protein using a linker to create PROTACs. | |||
T7760 |
Thalidomide-O-amido-C3-NH2 TFA
Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA |
E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | PROTAC |
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物,。 | |||
T39112 |
Propargyl-PEG2-urea-C3-triethoxysilane
Propargyl-PEG2-urea-C3-triethoxysilane |
||
Propargyl-PEG2-urea-C3-triethoxysilane is a PEG-based PROTAC linker utilized for PROTAC synthesis. | |||
T41115 |
N-Boc-C1-PEG5-C3-NH2
N-Boc-C1-PEG5-C3-NH2 |
||
N-Boc-C1-PEG5-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T39360 |
N-Boc-C1-PEG3-C3-NH2
N-Boc-C1-PEG3-C3-NH2 |
||
N-Boc-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17013 |
TCO-C3-PEG3-C3-amine
|
Others | Others |
TCO-C3-PEG3-C3-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T41077 |
Chloroacetamido-C-PEG3-C3-NHBoc
Chloroacetamido-C-PEG3-C3-NHBoc |
||
Chloroacetamido-C-PEG3-C3-NHBoc is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). | |||
T41130 |
Bis-SS-C3-sulfo-NHS ester
Bis-SS-C3-sulfo-NHS ester |
||
Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker employed for the synthesis of antibody-drug conjugates (ADCs). | |||
T18664 |
(S,R,S)-AHPC-C3-NH2
VH032-C3-NH2 |
Others | Others |
(S,R,S)-AHPC-C3-NH2 (VH032-C3-NH2) is a synthesized conjugate consisting of an E3 ligase ligand-linker and the VH032 based VHL ligand, which is commonly used in PROTAC technology. This compound serves as a key component in the synthesis of various PROTACs, including UNC6852. UNC6852 is a bivalent chemical degrader specifically targeting EED [1]. | |||
T40239 |
Tenofovir-C3-O-C15-CF3 ammonium
Tenofovir-C3-O-C15-CF3 ammonium |
||
Tenofovir-C3-O-C15-CF3 (ammonium) demonstrates prolonged half-life values compared to tenofovir in human liver microsomes. It exhibits potent anti-HIV activity in vitro and enhances pharmacokinetic properties in vivo. | |||
T39426 |
Thalidomide-O-amido-C3-NH2
Thalidomide-O-amido-C3-NH2,Cereblon Ligand-Linker Conjugates 16,E3LigaseLigand-LinkerConjugates52 |
||
Thalidomide-O-amido-C3-NH2 is a synthesized E3 ligase ligand-linker conjugate, which combines the cereblon ligand derived from Thalidomide with a linker utilized in PROTAC technology. | |||
T40238 |
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium
Tenofovir-C3-O-C12-trimethylsilylacetylene ammonium |
||
Tenofovir-C3-O-C12-trimethylsilylacetylene (ammonium) displays a prolonged half-life (t1/2) compared to tenofovir in human liver microsomes. Moreover, it demonstrates potent in vitro anti-HIV activity and improves in vivo pharmacokinetic properties. | |||
T18663 |
(S,R,S)-AHPC-C3-NH2 TFA (2361119-88-0 free base)
(S,R,S)-AHPC-C3-NH2 TFA,VH032-C3-NH2 TFA |
Others | Others |
(S,R,S)-AHPC-C3-NH2 TFA (VH032-C3-NH2 TFA) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used in PROTAC technology. (S,R,S)-AHPC-C3-NH2 can be used in the synthesis of a series of PROTACs, suc | |||
T14427 |
Azido-PEG3-C3-OH
|
Others | Others |
Azido-PEG3-C3-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T39215 |
Thalidomide-O-amido-C3-PEG3-C1-NH2
Thalidomide-O-amido-C3-PEG3-C1-NH2 |
||
Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized conjugate compound that serves as an E3 ligase ligand-linker. It features a cereblon ligand based on Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology. | |||
T14309 |
APN-C3-PEG4-alkyne
|
Others | Others |
APN-C3-PEG4-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14310 |
APN-C3-PEG4-azide
|
Others | Others |
APN-C3-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18764 |
TCO-PEG3-amide-C3-triethoxysilane
|
Others | Others |
TCO-PEG3-amide-C3-triethoxysilane is a polyethylene glycol (PEG)-based linker for proteolysis targeting chimeras (PROTACs) synthesis[1]. | |||
T17500 |
Azido-PEG3-amide-C3-triethoxysilane
|
Others | Others |
Azido-PEG3-amide-C3-triethoxysilane is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1]. | |||
T14745 |
Boc-NH-PEG4-C3-acid
|
Others | Others |
Boc-N-amido-PEG4-C3-acid is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T18177 | m-PEG3-amido-C3-triethoxysilane | Others | Others |
m-PEG3-amido-C3-triethoxysilane is a polyethylene glycol (PEG)-based linker commonly utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T17746 |
DBCO-C3-PEG4-amine
|
Others | Others |
DBCO-C3-PEG4-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T10326 |
Aniline-MPB-amino-C3-PBD
|
Others | Others |
Aniline-MPB-amino-C3-PBD is a cytotoxic agent comprised of the non-alkylating group. It is a sequence-selective DNA minor-groove binding agent. | |||
T12586 |
Py-MPB-amino-C3-PBD
|
Others | Others |
Py-MPB-amino-C3-PBD is a cytotoxic agent comprised non-alkylating group,with antimicrobial activity. | |||
T17747 |
DBCO-C3-PEG4-NH-Boc
|
Others | Others |
DBCO-C3-PEG4-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T14308 |
APN-C3-NH-Boc
tert-Butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate |
Others | Others |
APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18650 |
Ch55-O-C3-NH2
RAR ligand 1 |
Others | Others |
Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR. Through a linker, Ch55-O-C3-NH2 interacts with cIAP1 ligand Bestatin to form SNIPER[1]. | |||
T17729 |
Cl-C6-PEG4-C3-COOH
|
Others | Others |
Cl-C6-PEG4-C3-COOH, a PROTAC linker, is a suitable component for synthesizing chloroalkane-containing PROTACs (HaloPROTACs). | |||
T17475 |
Azido-C3-UV-biotin
UV Cleavable Biotin-PEG2-alkyne |
Others | Others |
Azido-C3-UV-biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T17546 |
Biotin-C1-PEG3-C3-amine TFA
|
Others | Others |
Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) based linker that serves as a crucial component in the synthesis of proteolysis targeting chimeras (PROTACs)[1]. | |||
T17581 |
Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne
|
Others | Others |
Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne functions as a PEG-based linker for PROTAC synthesis[1]. | |||
T14725 |
Boc-Gly-amido-C-PEG3-C3-amine
|
Others | Others |
Boc-Gly-amido-C-PEG3-C3-amine is a polyethylene glycol (PEG)-based PROTAC linker employed in PROTAC synthesis[1]. | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
||
Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13557 |
Ascr#5
Ascaroside C3 |
Others | Others |
Ascr#5 (asc-ωC3)是秀丽隐杆线虫中高度保守的蛔苷类物质,可调节秀丽隐杆线虫的多种反应。 | |||
TN2333 |
Ciwujianoside C3
刺五加苷C3,刺五加苷 C3 |
Others | Others |
Ciwujianoside C3 comes from Acanthopanax senticosus. | |||
T75466 | Palmarumycin C3 | ||
Palmarumycin C3 是从经1-十六碳烯处理的内生真菌Berkleasmium sp. Dzf12培养物中分离的螺双萘化合物,展现出较强的抗微生物及抗氧化活性。 | |||
T5070 |
LC3-mHTT-IN-AN2
5,7-二羟基-4-苯基香豆素,5,7-Dihydroxy-4-phenylcoumarin |
Antibacterial; Autophagy; ATTECs | Autophagy; Microbiology/Virology; PROTAC |
LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) 是一种 mHTT-LC3 接头化合物,可与突变亨廷顿蛋白(mHTT) 和 LC3B 相互作用。 它将 mHTT 靶向自噬体以等位基因选择性方式降低培养的亨廷顿病小鼠神经元中的 mHTT 水平。它存在于西番莲植物中,具有抗菌活性。 | |||
T41338 |
C30(ω-hydroxy) Ceramide (d18:1/30:0)
|
||
C30(ω-hydroxy) Ceramide (d18:1/30:0) 在生命科学相关研究中具有广泛的应用。 | |||
T40646 |
Lipoteichoic acid
|
Complement System | Immunology/Inflammation |
Lipoteichoic acid 是 Staphylococcus aureus 细胞壁的聚合物,通过诱导 C3 和抑制 CD55 来激活补体系统,通过 IGF-1 途径减少脂肪沉积。 | |||
T1571 |
Estriol
NSC-12169,Oestriol,雌三醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite | Endocrinology/Hormones; Immunology/Inflammation; Metabolism |
Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。 | |||
T1688 |
Pregnanediol
5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇 |
Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) 是一种黄体酮的主要代谢物 (metabolite),能够通过尿液排出。它提供了一种间接测定体内孕激素水平的方法。 | |||
T4768 |
Diethyl oxalpropionate
草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE |
Others; Endogenous Metabolite | Metabolism; Others |
Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。 | |||
T36990 |
Moenomycin Complex
|
||
Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. [1] The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.[1] | |||
TN5486 |
Pinobanksin 3-(2-methyl)butyrate
|
Apoptosis | Apoptosis |
Pinobanksin 3-(2-methyl)butyrate 是 Pinobanksin 衍生物。pinobanksin 是一种细胞凋亡诱导剂,可诱导 F6细胞凋亡。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00231 |
Complement C3 Protein, Bovine, Recombinant (His & SUMO)
Complement C3,C3 |
Bovine | E. coli |
Complement C3 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.5 kDa and the accession number is Q2UVX4. | |||
TMPH-02604 |
Complement C3 Protein, Mouse, Recombinant (His & SUMO)
C3,Complement C3 |
Mouse | E. coli |
Complement C3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession number is P01027. | |||
TMPY-05732 |
Complement C3 Protein, Cynomolgus, Recombinant (His)
complement component 3 |
Cynomolgus | HEK293 Cells |
Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.40 kDa and the accession number is XP_005587776.1. | |||
TMPY-05731 |
Complement C3 Protein, Human, Recombinant (His)
HEL-S-62p,CPAMD1,ARMD9,C3b,ASP,C3a,AHUS5,c... |
Human | HEK293 Cells |
Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024. | |||
TMPY-06767 |
Complement C3 Protein, Mouse, Recombinant (His)
HSE-MSF,complement component 3,Plp,AI255234,ASP |
Mouse | HEK293 Cells |
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.34 kDa and the accession number is NP_033908.2. | |||
TMPK-01268 |
Complement C2 Protein, Cynomolgus, Recombinant (His)
C2,CO2,Complement C2,C3/C5 convertase,ARMD14 |
Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. | |||
TMPH-03038 |
Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
Cobra venom factor,Complement C3 homolog,CVFk,CVF |
Naja kaouthia | E. coli |
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re... | |||
TMPH-02516 |
APOC3 Protein, Mouse, Recombinant (His & SUMO)
APOC3,ApoC-III,Apolipoprotein C3,Apolipopr... |
Mouse | E. coli |
APOC3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.9 kDa and the accession number is P33622. | |||
TMPH-02420 |
APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar)
ApoC-III,APOC3,Apolipoprotein C-III,Apo-CIII,Apolip... |
Cynomolgus | P. pastoris (Yeast) |
APOC3 Protein, Cynomolgus, Recombinant (His & SUMOstar) is expressed in yeast with N-6xHis-SUMOSTAR tag. The predicted molecular weight is 24.7 kDa and the accession number is P18659. | |||
TMPH-00948 |
APOC3 Protein, Human, Recombinant (His & SUMO)
Apolipoprotein C3,Apo-CIII,Apolipoprotein C-III,APO... |
Human | E. coli |
APOC3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.8 kDa and the accession number is P02656. | |||
TMPH-02607 |
Complement factor B Protein, Mouse, Recombinant (His)
C3/C5 convertase,Complement factor B,Cfb,Bf,H2-Bf |
Mouse | E. coli |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. | |||
TMPJ-00149 |
Complement Factor D/CFD Protein, Mouse, Recombinant (His)
C3 convertase activator,28 kDa adipocyte protein,Cf... |
Mouse | HEK293 Cells |
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the... | |||
TMPH-03272 |
Complement factor D Protein, Rat, Recombinant (His)
Adipsin,Df,Adn,C3 convertase activator,Complement f... |
Rat | P. pastoris (Yeast) |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. | |||
TMPH-03271 |
Complement factor D Protein, Rat, Recombinant (His & Myc)
Adn,C3 convertase activator,Properdin factor D,Comp... |
Rat | HEK293 Cells |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is P32038. | |||
TMPK-00755 |
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
C3 convertase activator,DF,AMBP-1,EC 3.4.21,EC 3.4.... |
Human | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recom... | |||
TMPK-00671 |
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Adipsin,CFD,ADN,Complement factor D,DF,AMBP-1,EC 3.4.21,FACT... |
Rhesus | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Rhesus macaq... | |||
TMPK-00151 |
Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
C3 convertase activator,AMBP-1,PFD,FACTOR D,CFD,ADN... |
Mouse | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recom... | |||
TMPH-02605 |
Complement C4-B Protein, Mouse, Recombinant (His)
C3 and PZP-like alpha-2-macroglobulin domain-contai... |
Mouse | E. coli |
Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. Catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. | |||
TMPY-02439 |
Rac2 Protein, Human, Recombinant (His)
p21-Rac2,HSPC022,Gx,EN-7,ras-related C3 botulinum t... |
Human | E. coli |
Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is attached to the small G-protein, the enzyme is inactivated. Release of the GDP and replace of the GTP cativate the GTPasee. Rac2 remains active until the GTP is hydrolyzed to GDP. Rac2 is a hematopoietic-specific Rho family GTPase implicated as an important constituent of the NADP... | |||
TMPY-01187 |
Rac1 Protein, Human, Recombinant (GST)
Rac-1,p21-Rac1,MIG5,ras-related C3 botulinum toxin ... |
Human | Baculovirus Insect Cells |
RAC1 is a GTPase that belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for RAC1 gene. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, bind... | |||
TMPH-01131 |
Complement C4-B Protein, Human, Recombinant (His & SUMO)
C4B,C3 and PZP-like alpha-2-macroglobulin domain-co... |
Human | E. coli |
Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-01283 |
Glypican 3/GPC3 Protein, Human, Recombinant (His)
SGBS1,DGSX,SGBS,MXR7,OCI-5,Glypican 3,SGB,SDYS,GTR2-2 |
Human | HEK293 Cells |
Glypican 3/GPC3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62 kDa and the accession number is P51654-1. | |||
TMPY-00502 |
Glypican 3/GPC3 Protein, Mouse, Recombinant (His)
OCI-5,glypican 3 |
Mouse | Baculovirus Insect Cells |
Glypican 3/GPC3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 62 kDa and the accession number is Q3TWB2. | |||
TMPY-05085 |
LRRC32 Protein, Human, Recombinant (His)
leucine rich repeat containing 32,GARP,D11S833E |
Human | HEK293 Cells |
LRRC32 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7. | |||
TMPY-02893 |
NT5C3A/NT5C3 Protein, Human, Recombinant
P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,... |
Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but... | |||
TMPY-06703 |
LRRC32 Protein, Mouse, Recombinant (hFc)
leucine rich repeat containing 32,D11S833Eh,Garp,D7H11S833E,... |
Mouse | HEK293 Cells |
LRRC32 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 93.38 kDa and the accession number is G3XA59. | |||
TMPJ-00719 |
CLIC3 Protein, Human, Recombinant (His)
CLIC3,Chloride intracellular channel protein 3 |
Human | E. coli |
Chloride intracellular channel protein 3 (CLIC3) is encoded by the CLIC3 gene. CLIC3 is a single-pass membrane protein which belongs to the chloride channel CLIC family. It contains one GST C-terminal domain and one GST N-terminal domain. Chloride intracellular channel protein 3 high expressed in the placental, lung and heart, low expressed in skeletal muscle, kidney and pancreas. Chloride intracellular channel protein 3 can insert into membranes and forms chloride ion channels, may participate ... | |||
TMPY-03437 |
DNAJC30 Protein, Human, Recombinant (His)
DnaJ (Hsp40) homolog, subfamily C, member 30,WBSCR18 |
Human | E. coli |
DNAJC30 is a member of the DNAJ molecular chaperone homology domain-containing protein family. DNAJC30 gene is deleted in williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. DNAJC30 is expressed in brain, heart, kidney, liver, lung, spleen, stomach and testis. It contains 1 J domain. DNAJC30 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, tho... | |||
TMPH-02979 |
SLC30A8 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. SLC30A8 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.0 kDa and the accession number is Q8BGG0. | |||
TMPH-01684 |
MAP1LC3C Protein, Human, Recombinant (His)
|
Human | E. coli |
Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins. MAP1LC3C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.7 kDa and the accession number is Q9BXW... | |||
TMPJ-00364 |
LRRC32 Protein, Human, Recombinant (hFc)
D11S833E,GARPGarpin,GARP,Garpin |
Human | HEK293 Cells |
Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRR... | |||
TMPY-00088 |
LRRC3B Protein, Human, Recombinant (His)
leucine rich repeat containing 3B,LRP15 |
Human | HEK293 Cells |
LRRC3B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is A1LNH5. | |||
TMPY-05106 |
Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated
SGB,GTR2-2,SDYS,DGSX,OCI-5,Glypican 3,SGBS,SGBS1,MXR7 |
Human | HEK293 Cells |
Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P51654-1. | |||
TMPH-01697 |
MORC3 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is ... | |||
TMPY-01715 |
CDC37 Protein, Human, Recombinant (GST)
cell division cycle 37,P50CDC37 |
Human | Baculovirus Insect Cells |
CDC37 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 70.7 kDa and the accession number is A0A024R7B7. | |||
TMPK-00337 |
GPC3 Protein-VLP, Human, Recombinant (aa 438-554)
OCI-5,SDYS,SGB,OCI5,MXR7,GTR2-2,GPC3,Glypican 3,SGB... |
Human | HEK293 Cells |
Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. GPC3 Protein-VLP, Human, Recombinant (aa 438-554) is expressed in HEK293 mammalian cells. The predicted molecular weight is 21.5 kDa and th... | |||
TMPJ-00380 |
AOC3 Protein, Human, Recombinant (His)
Membrane primary amine oxidase,HPAO,VAP-1,Semicarbazide-sens... |
Human | HEK293 Cells |
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inf... | |||
TMPY-03534 |
CDC37 Protein, Mouse, Recombinant (His & GST)
cell division cycle 37,p50,p50Cdc37 |
Mouse | Baculovirus Insect Cells |
CDC37 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.4 kDa and the accession number is Q61081. | |||
TMPH-02498 |
AKR1C3 Protein, Mouse, Recombinant (His & Myc)
Aldo-keto reductase family 1 member C13 |
Mouse | E. coli |
Catalyzes the dehydrogenation of 17-beta-hydroxysteroids. May also exhibit significant activity with a variety of cyclic and alicyclic alcohols. Uses both NAD and NADP, but the activity is much greater with NAD than with NADP. AKR1C3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 44.5 kDa and the accession number is Q8VC28. | |||
TMPY-05375 |
LRRC32 Protein, Human, Recombinant (His), Biotinylated
leucine rich repeat containing 32,D11S833E,GARP |
Human | HEK293 Cells |
LRRC32 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is A0A024R5J7. | |||
TMPH-01730 |
MYBPC3 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. MYBPC3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.8 kDa and the accession number is Q14896. | |||
TMPH-02049 |
ZC3H12A Protein, Human, Recombinant (His)
|
Human | E. coli |
ZC3H12A Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00416 |
Complement C3a Protein, Mouse, Recombinant
C3a,Complement Component C3a,Anaphylatoxin |
Mouse | E. coli |
Complement C3a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 KDa and the accession number is P01027. | |||
TMPJ-01379 |
TAC3 Protein, Human, Recombinant (His)
Neurokinin-B,Tachykinin-3,UNQ585/PRO1155,NKNB,ZNEUROK1,TA |
Human | E. coli |
Tachykinin 3 (TAC3) is a secreted protein that belongs to the Tachykinin family. Tachykinins are active peptides that excite neurons and evoke behavioral responses; they are potent vasodilators and secretagogues, and contract many smooth muscles in pregnancy. TAC3 is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. It is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension ... | |||
TMPY-06226 |
SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)
solute carrier family 39 member 6 |
Cynomolgus | HEK293 Cells |
Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as a... | |||
TMPJ-01423 |
GPC3 Protein, Rhesus macaque, Recombinant (His)
OCI5,GPC3,Glypican-3,MXR7,Intestinal protein OCI-5,... |
Rhesus | HEK293 Cells |
GPC3 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38 and 65-120 KDa and the accession number is XP_005594665.1. | |||
TMPH-03307 |
Glypican 3/GPC3 Protein, Rat, Recombinant (His)
|
Rat | P. pastoris (Yeast) |
Glypican 3/GPC3 Protein, Rat, Recombinant (His) is expressed in Yeast. | |||
TMPH-02322 |
SLC30A10 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
SLC30A10 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.9 kDa and the accession number is Q6XR72. | |||
TMPH-01903 |
APOBEC3C Protein, Human, Recombinant (GST)
APOBEC3C,Phorbolin I,PBI,APOBEC1-like,A3C,DNA dC->d... |
Human | E. coli |
APOBEC3C Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 49.8 kDa and the accession number is Q9NRW3. | |||
TMPY-00353 |
LRRC3B Protein, Human, Recombinant (hFc)
LRP15,leucine rich repeat containing 3B |
Human | HEK293 Cells |
LRRC3B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is A1LNH5. | |||
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