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Cat. No.	Product Name	Target	Signaling Pathways
T25175	BRD 9757 BRD9757,N-Hydroxy-1-cyclopentene-1-carboxamide,BRD-9757	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD 9757 (N-Hydroxy-1-cyclopentene-1-carboxamide) 是 HDAC6 的选择性抑制剂 (IC50 = 30 nM)。
T10602L	BRD 4354	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD 4354 是 HDAC5 和 HDAC9 的抑制剂，对 HDAC5 和 HDAC9 的 IC50 值分别为 0.85 和 1.88 μM。
T10603	BRD-6929	HIV Protease; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	BRD-6929 是一种选择性的脑渗透性的HDAC1和HDAC2抑制剂，IC50值为 1 和 8 nM。它对 HDAC1 和 HDAC2 有高亲和力，Ki 值为 0.2 和 1.5 nM。它可研究情绪相关行为。
T26894	BRD0209 BRD-0209,BRD 0209	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	BRD0209 是一种有效、选择性的 GSK3α/β 抑制剂
T30577	BRD0418 BRD 0418,BRD-0418	Others	Others
	BRD0418作为 TRIB1表达的上调因子，导致肝脏脂蛋白代谢从脂肪生成到清除的重新编程。
T23820	BRD32048 BRD-32048,BRD 32048	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	BRD32048 可以与与 ETV1直接结合，KD 为 17.1 μM。BRD32048调节 ETV1 介导的转录活性和 ETV1 驱动的癌细胞侵袭。 BRD32048可以抑制 ETV1 乙酰化并促进其降解。
T2292	FPH2 BRD-9424	Others	Others
	FPH2 (BRD-9424) 是促进 iPS 衍生肝细胞分化的小分子。它诱导原代人肝细胞的功能性增殖，有潜质用于研究肝脏疾病的新疗法。
T6506	FPH1 BRD-6125	Others	Others
	FPH1 (BRD-6125) 在体外能够提高人肝原代细胞的活性及数量，并促进 iPS 细胞向肝系分化。
T26901	BRD-9526 BRD 9526
	BRD-9526 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T22279	BRD0539	CRISPR/Cas9	DNA Damage/DNA Repair
	BRD0539 是一种具有细胞渗透性的 spCas9 抑制剂，可阻断 spCas9 与 DNA 的结合，抑制化脓性链球菌 Cas9 (SpCas9)。
T2353	BRD7116 BRD7716	DNA gyrase; Antibacterial	DNA Damage/DNA Repair; Microbiology/Virology
	BRD7116 与细菌 DNA 促旋酶竞争性结合，作用于LSCe 细胞，EC50值为200 nM。它具有细胞非自主抗白血病活性。
T30579	BRD4097	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD4097是HDAC1/2/3/8检测中的阴性对照品,是一种选择性组蛋白去乙酰化酶（HDAC3）抑制剂，可用于保护b 细胞和改善胰岛素抵抗，有助于促进认知功能和增强学习和记忆的形成。
T6793	BRD7552	Others	Others
	BRD7552 是PDX1转录因子诱导剂，它能够上调人类原代胰岛和导管细胞中 PDX1 的表达，诱导 PDX1 启动子的表观遗传变化与转录激活一致，提高胰岛素表达。其中 PDX1 是参与胰腺发育和β细胞功能的关键转录因子。
T21715	BRD6688	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD6688 为 HDAC2 的选择性抑制剂。本品可使原代小鼠神经元细胞中的 H4K12 和 H3K9 组蛋白的乙酰化作用增强。在 CK-p25 小鼠模型中，它可透过血脑屏障，并改善由p25 引起的神经退行性病变相关的记忆缺陷。
T26897	BRD2492	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD2492 是一种具有选择性和有效的 HDAC1 和 HDAC2 双重抑制剂，具有潜在的抗癌、抗肿瘤和抗增殖活性，抑制 HDAC1/2 、HDAC3 和 HDAC6。BRD2492 对乳腺癌细胞系的生长有抑制作用，诱导细胞凋亡。
T10602	BRD 4354 ditrifluoroacetate BRD 4354 ditrifluoroacetate (315698-07-8 free base)	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD 4354 (ditrifluoroacetate) is a moderately potent inhibitor of HDAC5 and HDAC9 (IC50s: 0.85 and 1.88 μM).
T2102	FH1 BRD-K4477,NSC 12407	Others	Others
	FH1 (NSC-12407) 可提高肝细胞功能，促进诱导多能干 (iPS) 衍生的肝细胞向更成熟的表型分化，并促使分化良好的肝细胞样细胞 (iHeps) 培养物的成熟。
T9329	BRD0639	Histone Methyltransferase	Chromatin/Epigenetic
	BRD0639 是首创的PRMT5-substrate adaptor interaction 的抑制剂。BRD0639 是一种 PRMT5 结合基序 (PBM) 竞争性抑制剂，可以支持 PBM 依赖的 PRMT5 活性的研究。
T7378	BRD9539	Histone Methyltransferase	Chromatin/Epigenetic
	BRD9539 是一种组蛋白甲基转移酶G9a 抑制剂，IC50为 6.3 μM，还抑制PRC2活性。
T35872	BRD-8000.3
	BRD-8000.3 is a narrow-spectrum, bactericidal antimycobacterial agent known for its specific inhibition of EfpA. It exhibits potent activity against wild-type strains and proves to be a valuable tool in tuberculosis research[1].
T6421	BRD73954	HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair
	BRD73954 是一种有效且特异性的 HDAC 抑制剂，对 HDAC6 和 HDAC8 的 IC50 分别为 36 nM 和 120 nM。
T14779	BRD7389	SGK; FLT; Pim; CDK; S6 Kinase; DAPK	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	BRD7389 是一种 RSK 家族激酶抑制剂，对 RSK1、RSK2 和 RSK3 的 IC50 分别为 1.5 μM、2.4 μM 和 1.2 μM。
T1923	BRD4770	Histone Methyltransferase	Chromatin/Epigenetic
	BRD4770 是组蛋白甲基转移酶G9a 抑制剂，可激活共济失调毛细血管扩张突变途径并诱导细胞衰老。它可抑制H3K9的二甲基和三甲基化，EC50为 5 µM。
T14778	BRD6989	IL Receptor; CDK; Interleukin	Cell Cycle/Checkpoint; Immunology/Inflammation
	BRD6989 是天然产物皮质抑素 A 的类似物，可抑制CDK8并上调IL-10，抑制重组 CDK8 或 CDK19 复合物的激酶活性。它选择性结合 CDK8 复合物，IC50约为 200 nM。
T10608	BRD5648 (R)-BRD0705	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	BRD5648 ((R)-BRD0705) 是 BRD0705 的阴性对照，BRD0705 是旁系选择性和口服有效的 GSK3α 抑制剂，Kd 为 4.8 μM，IC50为 66 nM。与 GSK3β (IC50为 515 nM) 相比，BRD0705 对 GSK3α 的选择性更高 (8 倍)。BRD0705 可用于急性髓细胞性白血病。
T8233	BRD3308	Apoptosis; HIV Protease; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	BRD3308 是一种高选择性的HDAC3抑制剂，IC50为 54 nM。它可激活HIV-1转录并破坏HIV-1潜伏期。它抑制由炎性细胞因子或糖脂毒性应激诱导的胰腺 β 细胞凋亡，并增加功能性胰岛素释放。
T10606	BRD0705	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	BRD0705 是一种具有旁系选择性的、口服具有活性的GSK3α抑制剂，其 IC50=66 nM，Kd=4.8 μM。它与 GSK3β (其 IC50=515 nM) 相比，对GSK3α的选择性更高 (8 倍)。它可用于研究急性髓细胞性白血病。
T70600	BRD-7880
	BRD-7880 is a potent and highly specific inhibitor of aurora kinases B and C.
T10605	BRD-K98645985	Others	Others
	BRD-K98645985 is a BAF transcriptional repression inhibitor (EC50: ~2.37 µM). It binds ARID1A-specific BAF complexes, potently reverses HIV-1 latency and prevents nucleosomal positioning.
T12664	(Rac)-BRD0705	Others	Others
	(Rac)-BRD0705 是 BRD0705 的活性较低的外消旋体。 BRD0705 是一种有效的特异性 GSK3α 抑制剂。
T16905	SNIPER(BRD)-1	Others	Others
	SNIPER(BRD)-1 is a chemical compound composed of a derivative of the IAP antagonist LCL-161 and the BET inhibitor (+)-JQ-1, linked together. It promotes the degradation of BRD4 through the ubiquitin-proteasome pathway and effectively degrades cIAP1, cIAP2, and XIAP with IC50 values of 6.8 nM, 17 nM, and 49nM, respectively[1].
T69692	BRD-K25923209
	BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.
T41198	BRD PHOTAC-I-3
	BRD PHOTAC-I-3 is a photoswitchable BET bromodomain degrader (PHOTAC, PHOtochemically TArgeting Chimera). BRD PHOTAC-I-3 comprises a ligand for an E3 ligase, a photoswitch, and the BET bromodomain targeting ligand (+)-JQ1. Exhibits cytotoxicity and degrades BRD4, BRD3 and to a lesser extent BRD2 in lymphoblast cells upon irradiation with 390 nm light, but not in the dark.
T10604	BRD-IN-3	Others	Others
	BRD-IN-3 is a highly potent PCAF bromodomain (BRD) inhibitor (IC50: 7 nM). It also exhibits activity against GCN5 and FALZ.
T17697	BRD7-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	BRD7-IN-1 是一种修饰的 BI7273 衍生物 (BRD7/9 抑制剂)。BRD7-IN-1 通过与 VHL 配体连接形成 PROTAC VZ185。VZ185 抑制 BRD7/9 的 DC50分别是 4.5 nM 和1.8 nM。
T12551	PROTAC BRD4 ligand-1	Epigenetic Reader Domain; Ligands for Target Protein for PROTAC	Chromatin/Epigenetic; PROTAC
	PROTAC BRD4 ligand-1 是 PROTAC GNE-987 靶向 BRD4 蛋白的配体，也是一种 BET 的抑制剂。
T14776	BRD4 Inhibitor-10	Epigenetic Reader Domain	Chromatin/Epigenetic
	BRD4 Inhibitor-10 是一种BRD4-BD1抑制剂，IC50为 8 nM。
T61361	BRD-8899
	BRD-8899是STK33的抑制剂，其IC50值为 11 nM。
T30584	BRD9092 BRD 9092,BRD-9092
	BRD9092 is an enhancer of reactive oxygen species that are nontoxic or cause genotype-selective cell death.
T26900	BRD7539 BRD-7539,BRD 7539
	BRD7539B is a Dihydroorotate dehydrogenase (DHODH) inhibitor . RD7539 shows to target PfDHODH (IC50 = 0.033 μM) selectively over human (Hs) DHODH (IC50 > 50 μM).
T30578	BRD3067 BRD-3067,BRD 3067
	BRD3067 is a negative control for tubastatin A.
T23821	BRD4884 BRD-4884,BRD 4884
	BRD4884 is a selective inhibitor of HDAC2 that acts by enhancing the learning and memory processes.
T30582	BRD56491 BRD-56491,BRD 56491
	BRD56491 is a non-toxic reactive oxygen species (ROS) enhancer that strongly elevates markers of oxidative stress without causing cell death.
T25176	BRD2577 BRD-2577,BRD 2577
	BRD2577 is an HDAC inhibitor, by suppressing multiple HDAC enzymes and modulating acetylation levels in cells.
T26898	BRD2879 BRD 2879,BRD-2879
	BRD2879 is a potent and cell-active inhibitor of IDH1-R132H (IC50 = 50 nM).
T26896	BRD1652 BRD-1652,BRD 1652
	BRD1652 is a highly selective and potent GSK3 inhibitor.
T30581	BRD5459 BRD-5459,BRD 5459
	BRD5459 is a kind of reactive oxygen species enhancer that is non-toxic or leads to genotype selective cell death. Brd5459 can selectively kill cancer cells in various in vitro and in vivo models.
T30583	BRD6897 BRD-6897,BRD 6897
	BRD6897 is a mitochondrial content inducer.
T26899	BRD50837 BRD-50837,BRD 50837
	BRD50837 is a potent and selective inhibitor of Sonic Hedgehog (Shh).
T6859	I-BRD9 GSK602	Epigenetic Reader Domain	Chromatin/Epigenetic
	I-BRD9 (GSK602) 是一种选择性的 BRD9 细胞抑制剂，pIC50 为 7.3。

化合物

Cat.No: T25175

Synonym: BRD9757,N-Hydroxy-1-cyclopentene-1-carboxamide,BRD-9757

Target: HDAC

Cat.No: T10602L

Target: HDAC

Cat.No: T10603

Target: HIV Protease, HDAC

Cat.No: T26894

Synonym: BRD-0209,BRD 0209

Target: GSK-3

Cat.No: T30577

Synonym: BRD 0418,BRD-0418

Target: Others

Cat.No: T23820

Synonym: BRD-32048,BRD 32048

Target: DNA/RNA Synthesis

Cat.No: T2292

Synonym: BRD-9424

Target: Others

Cat.No: T6506

Synonym: BRD-6125

Target: Others

Cat.No: T26901

Synonym: BRD 9526

Cat.No: T22279

Target: CRISPR/Cas9

Cat.No: T2353

Synonym: BRD7716

Target: DNA gyrase, Antibacterial

Cat.No: T30579

Target: HDAC

Cat.No: T6793

Target: Others

Cat.No: T21715

Target: HDAC

Cat.No: T26897

Target: HDAC

BRD 4354 ditrifluoroacetate

Cat.No: T10602

Synonym: BRD 4354 ditrifluoroacetate (315698-07-8 free base)

Target: HDAC

Cat.No: T2102

Synonym: BRD-K4477,NSC 12407

Target: Others

Cat.No: T9329

Target: Histone Methyltransferase

Cat.No: T7378

Target: Histone Methyltransferase

Cat.No: T35872

Cat.No: T6421

Target: HDAC

Cat.No: T14779

Target: SGK, FLT, Pim, CDK, S6 Kinase, DAPK

Cat.No: T1923

Target: Histone Methyltransferase

Cat.No: T14778

Target: IL Receptor, CDK, Interleukin

Cat.No: T10608

Synonym: (R)-BRD0705

Target: GSK-3

Cat.No: T8233

Target: Apoptosis, HIV Protease, HDAC

Cat.No: T10606

Target: GSK-3

Cat.No: T70600

BRD-K98645985

Cat.No: T10605

Target: Others

(Rac)-BRD0705

Cat.No: T12664

Target: Others

SNIPER(BRD)-1

Cat.No: T16905

Target: Others

BRD-K25923209

Cat.No: T69692

BRD PHOTAC-I-3

Cat.No: T41198

Cat.No: T10604

Target: Others

Cat.No: T17697

Target: Epigenetic Reader Domain

PROTAC BRD4 ligand-1

Cat.No: T12551

Target: Epigenetic Reader Domain, Ligands for Target Protein for PROTAC

BRD4 Inhibitor-10

Cat.No: T14776

Target: Epigenetic Reader Domain

Cat.No: T61361

Cat.No: T30584

Synonym: BRD 9092,BRD-9092

Cat.No: T26900

Synonym: BRD-7539,BRD 7539

Cat.No: T30578

Synonym: BRD-3067,BRD 3067

Cat.No: T23821

Synonym: BRD-4884,BRD 4884

Cat.No: T30582

Synonym: BRD-56491,BRD 56491

Cat.No: T25176

Synonym: BRD-2577,BRD 2577

Cat.No: T26898

Synonym: BRD 2879,BRD-2879

Cat.No: T26896

Synonym: BRD-1652,BRD 1652

Cat.No: T30581

Synonym: BRD-5459,BRD 5459

Cat.No: T30583

Synonym: BRD-6897,BRD 6897

Cat.No: T26899

Synonym: BRD-50837,BRD 50837

Cat.No: T6859

Synonym: GSK602

Target: Epigenetic Reader Domain

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