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Search Results for " 阿魏酸 "

1

抑制剂 & 化合物

26

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T73117	ROCK2-IN-5
	ROCK2-IN-5是一种复合型化合物，融合了Rho激酶抑制剂fasudil以及NRF2诱导剂咖啡酸和阿魏酸的结构元素。该化合物展示了优秀的多靶点作用特性和较高的耐受性。ROCK2-IN-5在针对SOD1基因变异型ALS研究中具备应用潜力。

化合物

Cat.No: T73117

Cat. No.	Product Name	Target	Signaling Pathways
TN2330	Phenethyl ferulate Caffeic Acid 3-Methyl Phenethyl Ester,阿魏酸苯乙酯,阿魏酸苯乙醇酯	Lipoxygenase; COX	Immunology/Inflammation; Metabolism; Neuroscience
	Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) 对化学诱导的结肠癌具有化学预防特性，可增强偶氮甲烷诱导的结肠肿瘤的细胞凋亡。它抑制环氧合酶(COX) 和 5-脂氧合酶 (5-LOX) ，IC50 值分别为 4.35 和 5.75 μM。
T0558	Dihydroferulic acid Dihydroconiferylic acid,氢化阿魏酸,Hydroferulic acid	Others	Others
	Dihydroferulic acid 是一种姜黄素的主要代谢产物，具有抗氧化/清除自由基的活性，其IC50=19.5 μM。它是香草酸的前体物质，也是人类肠道菌群的代谢产物。
T2215	Ferulic Acid Coniferic acid,Fumalic Acid,阿魏酸	FGFR; Endogenous Metabolite	Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
	Ferulic Acid (Coniferic acid) 是新型的成纤维细胞生长因子受体 1 (FGFR1)抑制剂, 在FGFR1和FGFR2的IC50分别为 3.78 和 12.5 μM。
T2S0007	Ferulic acid sodium 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate	FGFR; Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite	Angiogenesis; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
	Ferulic acid sodium (Sodium ferulic) 是新型的成纤维细胞生长因子受体 1 (FGFR1) 抑制剂。它对于FGFR1和FGFR2的IC50分别为 3.78 and 12.5 μM。
TN1643	Ferulamide 4-Hydroxy-3-methoxycinnamide,阿魏酸酰胺	PAFR; AChR	GPCR/G Protein; Neuroscience
	Ferulamide (4-Hydroxy-3-methoxycinnamide) 是从巴豆中分离的阿魏酸衍生物，具有抗胆碱酯酶活性。
T2821	Ethyl ferulate Ethyl 4'-hydroxy-3'-methoxycinnamate,Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate,阿魏酸乙酯,Ferulic acid ethyl ester,乙基阿魏酸	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	Ethyl ferulate (Ethyl 4'-hydroxy-3'-methoxycinnamate) 是一种从大茴香分离得到的阿魏酸的天然亲酯衍生物，能够诱导血红素氧合酶 1 ，保护大鼠神经元免受氧化应激。它能够保护神经元，使其受 β 淀粉样肽(1-42)导致的全身性的氧化应激和神经毒性。
TL0004	FERULIC ACID METHYL ESTER 阿魏酸甲酯,Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate	p38 MAPK; Autophagy	Autophagy; MAPK
	FERULIC ACID METHYL ESTER (Methyl ferulate) 是从大百部中分到的阿魏酸衍生物，具有抗氧化和抗炎作用。在原发性骨髓源性巨噬细胞中，它抑制 COX-2 的表达，降低 p-p38和 p-JNK 的水平。它能够透过细胞膜和血脑屏障，清除自由基，可研究神经退行性疾病。
T5679	(E)-Ferulic acid trans-Ferulic acid,反式阿魏酸,(E)-Coniferic acid	BCL; Ferroptosis; Wnt/beta-catenin; Endogenous Metabolite	Apoptosis; Cytoskeletal Signaling; Metabolism; Stem Cells
	(E)-Ferulic acid ((E)-Coniferic acid) 是阿魏酸的异构体，阿魏酸是在植物细胞壁中丰富存在的芳香族天然产物。它引起 β-catenin 的磷酸化，导致其蛋白酶体降解，增加促凋亡因子 Bax 的表达，降低促生存因子的表达。它在人肺癌细胞系 H1299 中发挥抗增殖和抗迁移作用。
T2889	Isoferulic acid Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸	Influenza Virus; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物，有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体，增强 β-内啡肽的分泌并增加体外葡萄糖的使用。
T3S0006	(E)-Ferulic acid methyl ester Methyl ferulate,Methyl (E)-ferulate,(E)-阿魏酸甲酯	IL Receptor; p38 MAPK; TNF; COX; NO Synthase; JNK; Antifection	Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience
	(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) 具有较强 DPPH 和 ABTS+自由基清除特性。
TN2030	P-Hydroxyphenethyl trans-ferulate 反式-阿魏酸对羟基苯乙酯	5-HT Receptor	GPCR/G Protein; Neuroscience
	p-Hydroxyphenethyl trans-ferulate 具有抗高血糖（酵母α-葡萄糖苷酶，IC5019.24 ± 1.73 µmol L-1），抗氧化，抗炎活性，也具有抗癌特性和血清素能特性。
TN1262	3-Feruloylquinic acid 3-O-阿魏酰奎尼酸,3-O-Feruloylquinic acid	Proteasome; Antifection	Microbiology/Virology; Proteases/Proteasome; Ubiquitination
	3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
T39570	Cycloartenyl ferulate Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯
	Cycloartenyl ferulate (also known as cycloartenol ferulate) is a representative triterpene alcohol with diverse biological properties, such as antioxidant, anti-allergic, anti-inflammatory, and anticancer activities.
TN1296	5-Feruloylquinic acid 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸	Tyrosinase; Sirtuin	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome
	5-Feruloylquinic acid (5-FQA) 表现出抗氧化作用和酪氨酸酶抑制作用。
T4394	Methyl Isoferulate	Others	Others
	Methyl Isoferulate 从毛竹叶中分离纯化。
T3S0012	coniferyl ferulate	P-gp; GST	Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
	Coniferyl ferulate 是从川芎中提取的一种天然产物，是强效的谷胱甘肽 S-转移酶抑制剂，强抑制人胎盘型谷胱甘肽 S-转移酶，IC50为 0.3 μM。它还可逆转多药耐药性并下调 P-糖蛋白。
TN1251	3-Feruloyl-1-Sinapoyl sucrose Feruloyl Sinapoyl sucrose,3-阿魏酸酯-1-芥子酰基蔗糖,3-Feruloyl-1-Sinapoyl sucrose
	3-Feruloyl-1-Sinapoyl sucrose (Feruloyl Sinapoyl sucrose) 是一种分离于 Polygala chamaebuxus 的糖苷。
T39198	5-Hydroxyferulic acid
	5-Hydroxyferulic acid is an important hydroxycinnamic acid compound and a metabolite in the phenylpropanoid pathway. It acts as a precursor for the biosynthesis of sinapic acid and functions as a non-esterified substrate for COMT.
TN1602	Eicosyl ferulate	Others	Others
	Eicosyl ferulate是一种天然产物，属于马兜铃科马兜铃属，其产品编号为 TN1602，CAS号为 133882-79-8。Eicosyl ferulate可用作对照参考。
TN1789	Isopropyl ferulate	Others	Others
	Isopropyl ferulate is a natural product
T13509	4-Vinylphenol	Apoptosis; Endogenous Metabolite	Apoptosis; Metabolism
	4-Vinylphenol 是酒中乳酸菌对香豆酸和阿魏酸的代谢产物，在白花蛇舌草中发现。 4-Vinylphenol 在体内诱导细胞凋亡。
T19316	Ethyl oleate	Others	Others
	Ethyl oleate 是由油酸和乙醇的缩合形成的脂肪酸酯。它是纳米结构脂质载体 (NLC) 中的液体脂质成分。其中 NLC 是一种口服有活性的反式阿魏酸的给药载体。
T3606	γ-Oryzanol 谷维素,Gamma-Oryzanol,Oliver,γ-谷维素,Gammariza	DNA Methyltransferase	Chromatin/Epigenetic
	γ-Oryzanol (Gamma-Oryzanol) 是一种从米糠油中分离出来的营养提取物，是含有甾醇和阿魏酸的混合物，有助于破坏皮肤中的自由基。它有效抑制小鼠纹状体中的 DNA 甲基转移酶(DNMTs)。它抑制DNMT1和DNMT3a，IC50分别为 3.2 和 22.3 μM。
T83231	8-O-4,8-O-4-Dehydrotriferulic acid
	8-O-4,8-O-4-Dehydrotriferulic acid 是从皂化后的玉米麸皮不溶性纤维中提取的一种脱氢三阿魏酸。
T27304	Farnesiferol C Farnesiferol-C
	Farnesiferol C induces apoptosis via regulation of L11 and c-Myc.
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...

天然产物

Phenethyl ferulate

Cat.No: TN2330

Synonym: Caffeic Acid 3-Methyl Phenethyl Ester,阿魏酸苯乙酯,阿魏酸苯乙醇酯

Target: Lipoxygenase, COX

Dihydroferulic acid

Cat.No: T0558

Synonym: Dihydroconiferylic acid,氢化阿魏酸,Hydroferulic acid

Target: Others

Cat.No: T2215

Synonym: Coniferic acid,Fumalic Acid,阿魏酸

Target: FGFR, Endogenous Metabolite

Ferulic acid sodium

Cat.No: T2S0007

Synonym: 阿魏酸钠,阿魏酸钠；3-甲氧基-4-羟基肉桂酸钠,Sodium ferulic,Ferulic acid sodium salt,Sodium ferulate

Target: FGFR, Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

Cat.No: TN1643

Synonym: 4-Hydroxy-3-methoxycinnamide,阿魏酸酰胺

Target: PAFR, AChR

Cat.No: T2821

Synonym: Ethyl 4'-hydroxy-3'-methoxycinnamate,Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate,阿魏酸乙酯,Ferulic acid ethyl ester,乙基阿魏酸

Target: Reactive Oxygen Species

FERULIC ACID METHYL ESTER

Cat.No: TL0004

Synonym: 阿魏酸甲酯,Methyl ferulate,Methyl 4'-hydroxy-3'-methoxycinnamate

Target: p38 MAPK, Autophagy

(E)-Ferulic acid

Cat.No: T5679

Synonym: trans-Ferulic acid,反式阿魏酸,(E)-Coniferic acid

Target: BCL, Ferroptosis, Wnt/beta-catenin, Endogenous Metabolite

Isoferulic acid

Cat.No: T2889

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Target: Influenza Virus, Adrenergic Receptor

(E)-Ferulic acid methyl ester

Cat.No: T3S0006

Synonym: Methyl ferulate,Methyl (E)-ferulate,(E)-阿魏酸甲酯

Target: IL Receptor, p38 MAPK, TNF, COX, NO Synthase, JNK, Antifection

P-Hydroxyphenethyl trans-ferulate

Cat.No: TN2030

Synonym: 反式-阿魏酸对羟基苯乙酯

Target: 5-HT Receptor

3-Feruloylquinic acid

Cat.No: TN1262

Synonym: 3-O-阿魏酰奎尼酸,3-O-Feruloylquinic acid

Target: Proteasome, Antifection

Cycloartenyl ferulate

Cat.No: T39570

Synonym: Cycloartenolferulate,Cycloartenolferulicacidester,环木菠萝烯醇阿魏酸酯

5-Feruloylquinic acid

Cat.No: TN1296

Synonym: 5-O-Feruloylquinic acid,5-FQA,5-O-阿魏酰奎尼酸

Target: Tyrosinase, Sirtuin

Methyl Isoferulate

Cat.No: T4394

Target: Others

coniferyl ferulate

Cat.No: T3S0012

Target: P-gp, GST

3-Feruloyl-1-Sinapoyl sucrose

Cat.No: TN1251

Synonym: Feruloyl Sinapoyl sucrose,3-阿魏酸酯-1-芥子酰基蔗糖,3-Feruloyl-1-Sinapoyl sucrose

5-Hydroxyferulic acid

Cat.No: T39198

Eicosyl ferulate

Cat.No: TN1602

Target: Others

Isopropyl ferulate

Cat.No: TN1789

Target: Others

Cat.No: T13509

Target: Apoptosis, Endogenous Metabolite

Cat.No: T19316

Target: Others

Cat.No: T3606

Synonym: 谷维素,Gamma-Oryzanol,Oliver,γ-谷维素,Gammariza

Target: DNA Methyltransferase

8-O-4,8-O-4-Dehydrotriferulic acid

Cat.No: T83231

Cat.No: T27304

Synonym: Farnesiferol-C

9(S),12(S),13(S)-TriHOME

Cat.No: T37272

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