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Cat. No. | Product Name | Target | Signaling Pathways |
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T71553 |
Ainsliadimer A
|
||
Ainsliadimer A 是一种来自 Ainsliaea macrocephala 的倍半萜内酯二聚体,具有抗肿瘤活性,可诱导各种癌细胞的细胞死亡。 | |||
T32576 |
Laserolide
|
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Laserolide is a sesquiterpene lactone. | |||
T32256 | Janerin | ||
Janerin is a sesquiterpene lactone. | |||
T32646 |
Leptocarpin
|
||
Leptocarpin is a sesquiterpene lactone extracted from Leptocarpha rivularis. | |||
T34932 |
Trichodermol
Roridin C |
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Trichodermol is a fungal sesquiterpene derived from the farnesyl diphosphate pathway. | |||
T32661 | Leucanthanolide | ||
Leucanthanolide is a sesquiterpene lactone from Montanoa leucantha. | |||
T26546 |
Acantholide
NSC 277282,NSC-277282,NSC277282 |
||
Acantholide is a Sesquiterpene lactone isolated from Acanthospermum glabratum. | |||
T34288 |
Repin
|
||
Repin, a plant responsible for Parkinson-like disease in horses, is the principal sesquiterpene lactone extracted from Russian knapweed. | |||
T34933 |
Trichodesmic acid
(+)-Trichodesmic acid |
||
Trichodesmic acid is a new bisabolane-type sesquiterpene. | |||
T33166 |
Majucin
|
||
Majucin is a sesquiterpene derived from Illicium sp. that possess complex caged chemical architecture and remarkable neurotrophic activities with potential activity against neurodegenerative diseases. | |||
T31575 | Drimane | ||
Drimane is a bicyclic sesquiterpene. It is the parent structure of many natural products with various biological activity. | |||
T31788 |
Fezelol
Feselol,Moschatol |
||
Fezelol is a sesquiterpene coumarin isolated from the fruits of Ferula badrakema. | |||
T32766 |
Linifolin A
NSC 153859,NSC-153859,NSC153859,PF 57,PF-57 |
||
Linifolin A is a sesquiterpene lactone extracted from Helenium aromaticum. | |||
T33860 | Pacifenol | ||
Pacifenol is a sesquiterpene isolated from sea weeds and marine alga Laurencia claviformis. | |||
T36817 |
Quadrone
|
||
Quadrone is a sesquiterpene originally isolated from A. terreus. It is cytotoxic to human carcinoma KB cells in vitro (EC50 = 1.3 μg/ml). | |||
T70240 |
Caparratriene
|
||
Caparratriene is a new sesquiterpene hydrocarbon isolated from Ocotea caparrapi with potential for significant growth inhibitory activityagainst CEM leukemia cells | |||
T69173 | Ambrosin | ||
Ambrosin is a sesquiterpene lactone and a potent NF-κβ inhibitor. It is currently being studied as a potential lead drug for Alzheimer disease therapeutics. | |||
T36906 | Nanangenine G | ||
Nanangenine G is a drimane sesquiterpene that has been found inAspergillus.1It is cytotoxic to NS-1 mouse myeloma cells (IC50= 47 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) | |||
T36905 | Nanangenine F | ||
Nanangenine F is a drimane sesquiterpene fungal metabolite that has been found inA. nanangensis.1It is active againstB. subtilis(IC50= 78 μg/ml) and cytotoxic to NS-1, DU145, and MCF-7 cancer and NFF non-cancerous cells (IC50s = 49, 95, 49, and 84 μg/ml, respectively). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) | |||
T71925 |
Isonanangenine B
|
||
Isonanangenine B is a drimane sesquiterpene lactone that has been found in Aspergillus. It decreases survivin mRNA expression in a reporter assay when used at concentrations of 13.6, 18.42, and 26.31 µM. Isonanagenine B (18.42 µM) inhibits STAT3 and NF-κB binding to the survivin promoter in chromatin immunoprecipitation (ChIP) assays. It also induces apoptosis in COLO 320DM cells. | |||
T36904 |
Nanangenine B
|
||
Nanangenine B is a drimane sesquiterpene that has been found inAspergillus.1It is active againstB. subtilis(IC50= 62 μg/ml) and cytotoxic to NS-1 mouse myeloma cells (IC50= 38 μg/ml). 1.Lacey, H.J., Gilchrist, C.L.M., Crombie, A., et al.Nanangenines: Drimane sesquiterpenoids as the dominant metabolite cohort of a novel Australian fungus, Aspergillus nanangensisBeilstein J. Org. Chem.152631-2643(2019) | |||
T36330 |
Terrecyclic Acid
|
||
Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity. It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells. In vivo, terrecyclic acid (0.1, 1, and 10 mg/ml) reduces the number of ascitic fluid tumor cells in a mouse model of P3... | |||
T34180 |
Psilostachyin C
NSC 106392 |
||
Psilostachyin c is a member of the class of compounds known as ambrosanolides and secoambrosanolides. Ambrosanolides and secoambrosanolides are sesquiterpene lactones from the Ambrosia family, with a backbone derivative of azuleno[6,5-b]furan-2-one (ambro |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5709 |
Cyperotundone
|
Others | Others |
Cyperotundone 是分离自 Nagarmotha (Cyperus rotundus) 中的一种倍半萜。 | |||
T9144 |
Telekin
|
Others | Others |
Telekin 是一种从中草药 Carpesium divaricatum 中分离出来的 eudesmane 型倍半萜内酯化合物,据报道可强烈抑制癌细胞的增殖。 | |||
T8249 |
Hexahydrofarnesyl acetone
植酮,Phytone |
Others; Antibacterial | Microbiology/Virology; Others |
Hexahydrofarnesyl acetone (Phytone) 是从Launaea mucronata 中分离得到的倍半萜,具有抗菌和抗炎活性,可研究缓解疼痛。 | |||
T23172 |
Polygodial
Tadeonal,水蓼二醛 |
Antifungal | Microbiology/Virology |
Polygodial (Tadeonal) 是一种抗真菌增效剂和抗生素。它是一种倍半萜,具有抗痛觉过敏的作用。 | |||
T11685 |
Isolongifolene
异长叶烯,(-)-Isolongifolene |
Apoptosis; Others | Apoptosis; Others |
Isolongifolene ((-)-Isolongifolene) 是一种从调料九里香中分离的三环倍半萜烯,具有抗氧化,抗炎,抗癌和神经保护的特性。它通过调节 PI3K/AKT/GSK-3β 信号通路来减轻鱼藤酮诱导的氧化应激,线粒体功能障碍和细胞凋亡。 | |||
T8898 |
Granilin
大叶土木香内酯,Graniline |
Others; Antibacterial; Antifungal | Microbiology/Virology; Others |
Granilin (Graniline) 是存在于Carpesium triste 的花蕾中的一种倍半萜内酯,可作杀菌和杀真菌剂。 | |||
T8292 |
(-)-Cedrene
α-柏木烯,Alpha-Cedrene |
Others; Antibacterial | Microbiology/Virology; Others |
(-)-Cedrene (Alpha-Cedrene) 是一种来自雪松油中的倍半萜烯,有抗白血病、抗菌和抗肥胖作用。 | |||
T5712 |
zerumbone
花薑酮,球姜酮 |
Antioxidant; HSV | Microbiology/Virology; oxidation-reduction |
Zerumbone 是从Zingiber zerumbetSmith 的根茎中分离的一种单环倍半萜烯,可有效抑制Epstein-Barr 病毒的激活,IC50为 0.14 mM,具有抗癌、抗炎、抗氧化和抗增殖的作用。 | |||
T2808 |
Bilobalide
白果内酯,银杏内酯,(-)-Bilobalide |
Apoptosis; Endogenous Metabolite; Autophagy | Apoptosis; Autophagy; Metabolism |
Bilobalide ((-)-Bilobalide) 是银杏叶中的的一种倍半萜三内酯成分,抑制 NMDA 诱导的胆碱流出,IC50值为 2.3 µM。它通过激活 SH-SY5Y 细胞中的 PI3K/Akt 通路来防止细胞凋亡。对神经元发挥保护和营养作用。 | |||
T8516 |
Levomenol
没药醇,(-)-α-BISABOLOL,(-)-α-红没药醇 |
Others | Others |
Levomenol ((-)-α-BISABOLOL) 是一种单环倍半萜醇,具有有神经保护、抗氧化、抗炎和抗凋亡的作用。它可减轻三叉神经性疼痛啮齿动物模型的伤害性行为和中枢敏感性。它通过减少小鼠永久性局灶性脑缺血诱导的促炎标志物,防止神经元损伤和记忆缺陷。 | |||
TQ0234 |
Epoxymicheliolide
1β,10β-Epoxymicheliolide,环氧木香内酯 |
Others | Others |
Epoxymicheliolide (1β,10β-Epoxymicheliolide) 是木香内酯衍生物的一种。 | |||
T22857 |
Illudin S
|
Apoptosis; DNA Alkylator/Crosslinker; Antifungal | Apoptosis; DNA Damage/DNA Repair; Microbiology/Virology |
Illudin S (ILS)是一种真菌倍半萜次生代谢物,具有很强的遗传毒性和细胞毒性 | |||
T5688 |
Micheliolide
|
NOS; NF-κB; COX | Immunology/Inflammation; Neuroscience; NF-κB |
Micheliolide 是一种倍半萜内酯,能够抑制各种炎症反应。它能减弱高糖刺激的NF-κB 活化,IκBα的降解,和MCP-1,TGF-β1,FN 在鼠系膜细胞的表达。 | |||
T13686 |
Ergolide
|
NF-κB | NF-κB |
Ergolide, a sesquiterpene lactone extracted from the dried flowers of Inula Britannica, effectively hinders the expression of inducible nitric oxide synthase and cyclo-oxygenase-2 in RAW 264.7 macrophages by deactivating NF-κB. | |||
T5793 |
Britannin
|
Apoptosis; AMPK; Autophagy | Apoptosis; Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling |
Britannin 是分离于旋覆花的一种倍半萜内酯,可通过激活由 ROS 调节的 AMPK 来诱导肝癌细胞凋亡和自噬,具有抗增殖和抗炎活性。 | |||
TQ0096 |
Scabertopin
|
Others | Others |
Scabertopin 是一种从地胆草中分离得到倍半萜内酯,具有抗癌和抑菌活性。 | |||
TN7254 |
(E,E)-Farnesol
(2E,6E)-Farnesol |
Others | Others |
(E,E)-Farnesol ((2E,6E)-Farnesol) 是一种由细菌、原生动物、真菌、植物和动物产生的倍半萜无环醇。(E,E)-Farnesol 可促进血管扩张。 | |||
T2904 |
Sclareolide
香紫苏内酯,Norambreinolide |
Others; Antibacterial | Microbiology/Virology; Others |
Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物,具有抗菌和细胞毒性作用。 | |||
T3865 |
beta-Eudesmol
β-桉叶醇,Beta-Selinenol,beta-桉叶醇 |
TRP/TRPV Channel; AChR | Membrane transporter/Ion channel; Neuroscience |
beta-Eudesmol (Beta-Selinenol) 是天然的含氧倍半萜烯,可激活hTRPA1,EC50值为 32.5 μM。Beta-Eudesmol 有增加食欲的功效。 | |||
T2896 |
Alantolactone
土木香内酯,helenin,Eupatal,Helenine,(+)-Alantolactone,Alant camphor,土木香脑,Inula camphor |
Apoptosis; STAT; TGF-beta/Smad | Apoptosis; JAK/STAT signaling; Stem Cells |
Alantolactone (Inula camphor) 是一种STAT3的选择性抑制剂,可诱导癌症相关的凋亡,具有抗肿瘤活性。 | |||
TN1159 |
(1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one
[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one |
Others | Others |
(1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one ([(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygemacra-1(10),7,11-trien-6-one) 是一种来自姜黄的倍半萜。 | |||
T6S1049 |
Wilforine
|
ATPase | Membrane transporter/Ion channel |
Wilforine 是一倍半萜吡啶化合物,T. wilfordii 植物中的重要生物活性化合物,可有效治疗特发性肺纤维化。它具有抗炎和杀虫活性。 | |||
T2916 |
Patchouli alcohol
百秋李醇,Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol,广藿香醇 |
Antibacterial; Antifungal | Microbiology/Virology |
Patchouli alcohol (Patchoulol) 是一种从广藿香中提取的天然三环倍半萜,有抗幽门螺杆菌和抗炎活性。 | |||
T36528 |
Illudin M
|
Apoptosis; DNA Alkylator/Crosslinker | Apoptosis; DNA Damage/DNA Repair |
Illudin M是真菌O. illudens中的一种细胞毒性倍半萜,能使DNA烷基化。它对 HL-60 人类白血病细胞的细胞毒性为 6-100 nM。Illudin M 具有抗癌活性,是抗癌化合物的前药,可用于合成抗癌化合物。 | |||
TN6835 |
(E)-β-Farnesene
(6E)-7,11-dimethyl-3-methylidenedodeca-1,6,10-triene,trans-β-Farnesene |
Antifungal | Microbiology/Virology |
(E)-β-Farnesene (trans-β-Farnesene) 是一种存在于 Phlomis aurea Decne中的倍半萜烃,是许多蚜虫报警信息素的主要成分,可中断蚜虫摄食。(E)-β-Farnesene 通过破坏昆虫激素平衡来损害 Chilo suppressalis 幼虫的发育和存活。 | |||
T36473 |
trans-Nerolidol
|
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trans-Nerolidol is a sesquiterpene that has been found in various plants, includingC. sativa, and has diverse biological activities, including antimicrobial, antioxidant, anticancer, and insecticidal properties.1,2,3,4In a disc assay,trans-nerolidol inhibits the growth ofS. aureus,B. subtilis,E. coli, andS. cerevisiaewith zones of inhibition measuring 10, 9, 10, and 4 mm, respectively.2It reduces viability of CaCo-2 adenocarcinoma cells with an IC50value of 28.7 mg/L and reduces production of re... | |||
TN6735 |
Bigelovin
|
Apoptosis; Reactive Oxygen Species; Retinoid Receptor; Autophagy; RAR/RXR | Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB |
Bigelovin 是从海百合中分离得到的一种倍半萜内酯,是选择性视黄素 X 受体 α 激动剂。它通过抑制ROS 的生成来调节 mTOR 信号通路。它诱导凋亡和自噬,有抗肿瘤活性。 | |||
T9279 |
nerolidol acetate
|
Others | Others |
Nerolidol acetate是一种具有抗癌、抗炎、抗菌和抗虫的活性的天然倍半萜。Nerolidol acetate可抑制寄生虫活动,抑制吸血虫病、线虫病以及疟疾等。Nerolidol acetate可保护细胞免受脂质、蛋白质和 DNA 的氧化损伤,对小鼠海马神经细胞具有保护作用。 | |||
TN1405 |
Arnicolide D
山金车内酯 D,山金车内酯D |
Akt; Caspase; PI3K; STAT; mTOR | Apoptosis; Cytoskeletal Signaling; JAK/STAT signaling; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells |
Arnicolide D 是从石胡荽中分离出的一种倍半萜内酯,以浓度和时间依赖性方式抑制鼻咽癌细胞活力。它调节细胞周期,激活 caspase 信号通路并抑制 PI3K/AKT/mTOR 和 STAT3 信号通路。 | |||
T4672 |
Brevilin A
|
Apoptosis; Anti-infection; JAK; STAT; Autophagy | Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; JAK/STAT signaling; Microbiology/Virology; Stem Cells |
Brevilin A 是从Centipeda minima 中分离的倍半萜内酯,具有抗癌活性。它通过线粒体途径和 PI3K/AKT/mTOR 失活诱导结肠腺癌细胞 CT26 的凋亡和自噬。它是一种选择性JAK-STAT 信号通路抑制剂,通过减弱 JAK 信号和 阻塞 STAT3 信号起作用。 | |||
T32622 |
Ledol
(+)-Ledol |
||
Ledol is a sesquiterpene alcohol from Renealmia chrysotrycha. | |||
T32860 | Longiborneol | ||
Longiborneol is a sesquiterpene alcohol. | |||
T34513 |
Santalene
|
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Santalene is a fragrance sesquiterpene that is responsible for the fragrance of sandalwood oil. | |||
T40204 |
Wilfordinine D
|
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Wilfordinine D is a natural sesquiterpene alkaloid. | |||
T34504 | Samarcandin | ||
Samarcandin is a natural sesquiterpene-coumarin that is isolated from F. assa-foetida. | |||
T40578 | β-Bisabolene | ||
β-Bisabolene is a sesquiterpene isolated from opoponax ( Commiphora guidotti ). β-Bisabolene, an anti-cancer agent , can be used for the study of breast cancer. | |||
T83160 |
Agarsenone
|
||
Agarsenone,一杜松烷倍半萜,可分离自没药(Commiphora erythraea)树脂。 | |||
T11274 |
Ferulenol
|
Others | Others |
Ferulenol, a sesquiterpene prenylated coumarin derivative, exhibits potent antimycobacterial activity and haemorrhagic action. This compound selectively targets succinate ubiquinone reductase within the ubiquinone cycle as its specific mode of inhibition. | |||
T81166 | Shizukaol G | ||
Shizukaol G为一种从Chloranthus japonicus根部分离得到的二聚倍半萜烯。 | |||
TN3780 | Deacetyleupaserrin | Others | Others |
Deacetyleupaserrin is an antileukemic sesquiterpene lactone. | |||
T81981 |
Kissoone A
|
||
Kissoone A (compound 1)为缬草根中提取的三萜类化合物。 | |||
T81884 |
Madolin U
|
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Madolin U是德马属倍半萜类化合物,从紫堇属植物中分离得到。 | |||
T40582 |
α-Farnesene
|
||
α-Farnesene, a sesquiterpene, is a herbivore-induced plant volatile (HIPV) that plays a significant role in insect resistance across various plant species. | |||
T15467 |
Helenalin
|
Others | Others |
Helenalin is a selective inhibitor of transcription factor NF-κB by direct targeting of p65. It is an anti-inflammatory sesquiterpene lactone compound with alkylating activity. Through its ability to target the cysteine sulfhydryl groups in the p65 subunit of NF-κB, helenalin effectively inhibits its DNA binding. | |||
T80869 |
Versicolactone B
|
||
Versicolactone B,一种从Viola yedoensis分离得到的倍半萜,对经典途径和替代途径均显示出抗补体活性。 | |||
T83442 |
17(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene
|
||
17(13→14)-Abeo-ent-3S*,13S*,16-trihydroxystrob-8(15)-ene是一款具有抗炎特性的天然倍半萜内酯。 | |||
T80688 |
β-Patchoulene
|
||
β-Patchoulene, 一种三环倍半萜类化合物,源自广藿香油,主要应用于炎症性疾病治疗。 | |||
T75543 | Angulatin G | ||
Angulatin G (Celangulatin E) 是一种具有 β-二氢琼脂糖呋喃倍半萜骨架的杀虫倍半萜多元醇酯,可从Celastrusangulatus 根皮中分离得到。 Angulatin G 对Mythimna separata 显示LD50为 1656.4 μg/mL。 | |||
T81167 | Shizukanolide | ||
Shizukanolide,一种倍半萜内酯,源自金兰属 (Chloranthus japonicus) 植物,其脱氢衍生物展现出中等抗真菌活性。 | |||
T78469 |
α-Copaene
|
||
α-Copaene,一种倍半萜烃,具有水果挥发物性质,可作为橄榄实蝇(Bactrocera oleae)的产卵促进剂。 | |||
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