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Search Results for " pyrimidine "

398

抑制剂 & 化合物

25

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T2075	Pyrazolo[1,5-a]pyrimidine 4h	Others	Others
	Pyrazolo[1,5-a]pyrimidine 4h 是一种吗啉衍生物，是腺苷 A2A 受体的选择性拮抗剂。在帕金森病和亨廷顿舞蹈症的动物模型中，它已被证明具有神经保护作用。
T1696	2-(1-Piperazinyl)pyrimidine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	2-(1-Piperazinyl)pyrimidine 用作抗焦虑药。
T7256	4-Chlorothieno[3,2-d]pyrimidine
	4-Chlorothieno[3,2-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T7256，CAS号为 16269-66-2。
T50078	2-(pentylsulfanyl)pyrimidine-4,6-diol	GPR	Endocrinology/Hormones; GPCR/G Protein
	2-(pentylsulfanyl)pyrimidine-4,6-diol 是一种新型 GRP84 激动剂。
T9366	Pyrazoloadenine 4-Aminopyrazolo[3,4-d]pyrimidine	ROS	Immunology/Inflammation
	Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) 是人黄嘌呤氧化酶的抑制剂。
T8621	ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE	Others	Others
	ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE 用于制备作为蛋白激酶抑制剂的嘧啶并嘧啶。
T7451	2-Cyanopyrimidine 2-氰基嘧啶,2-cyano-Pyrimidine	Cysteine Protease	Proteases/Proteasome
	2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) 是半胱氨酸蛋白酶组织蛋白酶 K (cysteine protease cathepsin K) 的非选择性抑制剂(IC50:170 nM)。它能够用于骨质疏松症的研究。
T8613	1-Ethyl-6-aminouracil 6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE,1-乙基-6-氨基脲嘧啶	Adenosine Receptor	GPCR/G Protein; Neuroscience
	1-Ethyl-6-aminouracil (6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE) 是合成一系列新的取代黄嘌呤的中间体，这些黄嘌呤对人腺苷 A2B 受体具有高亲和力和选择性。
T9945	MNK8 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione	STAT	JAK/STAT signaling; Stem Cells
	MNK8 (3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione) 是一种有效的STAT3抑制剂，降低STAT3与DNA 结合的能力，对肝癌细胞也有良好的生长抑制作用。
T50079	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine	Others	Others
	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine 可用于开发新的脱氧胞苷激酶（dCK）抑制剂。
T16922	SPOP-IN-6b 2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide	Others	Others
	SPOP-IN-6b 是一种有效的斑点型 POZ 蛋白 (SPOP) 抑制剂，IC50 为 3.58 μM，可用于肾癌治疗的研究。
T24639	PIH pyrimidine-indole hybrid
	PIH is a ciliogenesis inhibitor by microtubule destabilization that acts by antagonizing Hh signaling by repressing cilia biogenesis and disassembly of alpha-tubulin in its stabilized form.
T13017	STL127705 Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione	DNA-PK; Others	DNA Damage/DNA Repair; Others; PI3K/Akt/mTOR signaling
	STL127705 (Compound L) 是一种有效的 Ku 70/80 异二聚体蛋白抑制剂，抑制 Ku70/80-DNA 相互作用，IC50 为 3.5 μM。它抑制 Ku 依赖性 DNA-PKCS 激酶的激活，IC50 为 2.5 μM。
T67762	2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid	Others	Others
	2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid 属于嘧啶家族，已被证明具有抗炎、抗惊厥和抗肿瘤的特性。
T2476	INCB032304 4-(1H-吡唑-4-基)-7-((2-(三甲基硅烷基)乙氧基)-甲基)-7H-吡咯并[2,3-D]嘧啶,4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine	Others	Others
	INCB032304是一种重要的医药中间体。可用于制备janus 激酶抑制剂Ruxolitinib phosphate（I008849），也可于制备Barretinib。
T67877	2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid	Others	Others
	2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid 常用来合成具有抗癌抗肿瘤作用的化合物。
T9048	Ecamsule	Others	Others
	Ecamsule 是一种亚苄基樟脑衍生物，其中许多以其出色的光稳定性而闻名。可添加到防晒霜中以过滤掉 UVA 射线。
T36870	5,6-dihydro-5-Fluorouracil 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione	Others	Others
	5,6-dihydro-5-Fluorouracil (5-FUH2)是 5-FU 的无活性代谢产物，可用于用于研究机体代谢。
T4348	Syk Inhibitor II	5-HT Receptor; Syk	Angiogenesis; GPCR/G Protein; Neuroscience; Tyrosine Kinase/Adaptors
	Syk Inhibitor II 是一种可渗透细胞、具有 ATP 竞争性的嘧啶-甲酰胺化合物，可选择性且可逆地抑制 Syk，IC50为 41 nM。
T64428	4,6-Dichloro-2-(propylthio)pyrimidine
	4,6-Dichloro-2-(propylthio)pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64428，CAS号为 1401318-10-2。
T16911	Sorivudine BV-araU,索立夫定	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Sorivudine (BV-araU) 是口服有效的，嘧啶核苷抗代谢药物。它的抗病毒活性来自某些 DNA 病毒中存在的特定胸苷激酶选择性转化为核苷酸，从而反过来会干扰病毒 DNA 合成。
T66446	2-(Propylthio)pyrimidine-4,6-diol
	2-(Propylthio)pyrimidine-4,6-diol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66446，CAS号为 145783-12-6。
T5168	EGFR-IN-12 EGFR Inhibitor	Apoptosis; EGFR	Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	EGFR-IN-12 (EGFR Inhibitor) 是一种 4,6-二取代的嘧啶，可诱导细胞凋亡，具有抗肿瘤活性。它是ATP 竞争性，不可逆且高度选择性的EGFR 抑制剂，IC50为 21 nM。它对EGFR 的选择性高于 HER4 和 55种其他激酶。它还抑制突变型EGFRL858R 和EGFRL861Q，IC50分别为 63 nM 和 4 nM。
T66602	4-Chloro-5H-pyrrolo[3,2-d] pyrimidine
	4-Chloro-5H-pyrrolo[3,2-d] pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66602，CAS号为 84905-80-6。
T64959	Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate
	Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64959，CAS号为 5909-24-0。
T66488	6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione
	6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66488，CAS号为 18592-13-7。
T66222	4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine
	4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66222，CAS号为 145783-14-8。
TNU1019	6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine
	6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1018	6-Amino-4-chloropyrazolo[3,4-d]pyrimidine
	6-Amino-4-chloropyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU0659	4-Chloro-1H-pyrazolo[3,4-d]pyrimidine
	Heterocyclic compound-purine, intermediate and building block-electrophile, nucleoside base
T66608	2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine
	2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66608，CAS号为 90213-66-4。
TNU0611	4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine
	Heterocyclic compound –purines, intermediate and building block; Used for modified nucleosides and nucleic acids
T65517	4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
	4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65517，CAS号为 479633-63-1。
T65530	4-Chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine
	4-Chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65530，CAS号为 16372-08-0。
T64808	5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine
	5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64808，CAS号为 16285-82-8。
T9309	mTOR inhibitor 11
	mTOR inhibitor 11 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T9309，CAS号为 1195785-35-3。
TNU0717	4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine
	Heterocyclic compound - purine; Intermediate and building blocks– electrophile and nucleophile; Nucleoside base
T64531	2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine
	2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64531，CAS号为 84746-24-7。
T7518	Deoxycytidine triphosphate trisodium salt 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) 是可用于 DNA 合成的核苷三磷酸，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T66943	5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione
	5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66943，CAS号为 73742-45-7。
TNU1015	4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine
	4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
T66583	Ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate
	Ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66583，CAS号为 211230-35-2。
TNU1032	7-(2-Deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
	Nucleoside Derivatives - 7-Deaza-purine nucleosides; 6-De-aminopurine nucleosides
T66523	4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid
	4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T66523。
T8005	Cardiogenol C hydrochloride 2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐,Cardiogenol C HCl,Cardiogenol C	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Cardiogenol C hydrochloride (Cardiogenol C) 是一种细胞渗透性嘧啶诱导剂，能够促使 ESCs 分化为心肌细胞。在有限的可塑性范围内，它可以对已经沿袭的祖细胞类型产生心肌生成效应，是一种心肌生成试剂，在动物模型中可以用作细胞移植研究中提高心脏修复的工具。
TNU0323	4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
	4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a Nucleoside Derivative - 7-deaza-8-aza purine nucleoside.
TNU0280	4,6-Diamino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
	Nucleoside Derivatives - 8-Aza-7-deaza-purine nucleoside; 2-Modified purine nucleoside
TNU1020	6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine
	6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine bolongs toIntermediates and Building Blocks - Nucleoside Base; Multi-functional; Heterocyclic Compounds - Purine; Scaffold and Template.
TNU1478	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid
	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid is a PNA-related Derivative; Heterocyclic Compound - Fused polyheterocycle.
TNU1477	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid benzyl ester
	5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid benzyl ester 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 TNU1477。

化合物

Pyrazolo[1,5-a]pyrimidine 4h

Cat.No: T2075

Target: Others

2-(1-Piperazinyl)pyrimidine

Cat.No: T1696

Target: Adrenergic Receptor

4-Chlorothieno[3,2-d]pyrimidine

Cat.No: T7256

2-(pentylsulfanyl)pyrimidine-4,6-diol

Cat.No: T50078

Target: GPR

Pyrazoloadenine

Cat.No: T9366

Synonym: 4-Aminopyrazolo[3,4-d]pyrimidine

Target: ROS

ETHYL 4-AMINO-2-(METHYLTHIO)PYRIMIDINE-5-CARBOXYLATE

Cat.No: T8621

Target: Others

2-Cyanopyrimidine

Cat.No: T7451

Synonym: 2-氰基嘧啶,2-cyano-Pyrimidine

Target: Cysteine Protease

1-Ethyl-6-aminouracil

Cat.No: T8613

Synonym: 6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE,1-乙基-6-氨基脲嘧啶

Target: Adenosine Receptor

Cat.No: T9945

Synonym: 3-methyl-6-(naphthalen-1-yl)pyrimidine-2,4(1H,3H)-dione

Target: STAT

2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine

Cat.No: T50079

Target: Others

Cat.No: T16922

Synonym: 2-Imino-10-methyl-N-(3-morpholinopropyl)-5-oxo-1-phenethyl-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxamide

Target: Others

Cat.No: T24639

Synonym: pyrimidine-indole hybrid

Cat.No: T13017

Synonym: Compound L,7-[[2-(3,4-Dimethoxyphenyl)ethyl]amino]-3-(3-fluorophenyl)pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione

Target: DNA-PK, Others

2-Oxo-6-phenyl-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid

Cat.No: T67762

Target: Others

Cat.No: T2476

Synonym: 4-(1H-吡唑-4-基)-7-((2-(三甲基硅烷基)乙氧基)-甲基)-7H-吡咯并[2,3-D]嘧啶,4-(1H-Pyrazol-4-yl)-7-((2-(trimethylsilyl)ethoxy)-methyl)-7H-pyrrolo[2,3-d]pyrimidine

Target: Others

2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxylic acid

Cat.No: T67877

Target: Others

Cat.No: T9048

Target: Others

5,6-dihydro-5-Fluorouracil

Cat.No: T36870

Synonym: 5-fluorodihydrouracil,5-Fluoro-dihydro-pyrimidine-2,4-dione

Target: Others

Syk Inhibitor II

Cat.No: T4348

Target: 5-HT Receptor, Syk

4,6-Dichloro-2-(propylthio)pyrimidine

Cat.No: T64428

Cat.No: T16911

Synonym: BV-araU,索立夫定

Target: DNA/RNA Synthesis

2-(Propylthio)pyrimidine-4,6-diol

Cat.No: T66446

Cat.No: T5168

Synonym: EGFR Inhibitor

Target: Apoptosis, EGFR

4-Chloro-5H-pyrrolo[3,2-d] pyrimidine

Cat.No: T66602

Ethyl 4-chloro-2-(methylthio)pyrimidine-5-carboxylate

Cat.No: T64959

6-(Chloromethyl)pyrimidine-2,4(1H,3H)-dione

Cat.No: T66488

4,6-Dichloro-5-nitro-2-(propylthio)pyrimidine

Cat.No: T66222

6-Amino-4-methoxypyrazolo[3,4-d]pyrimidine

Cat.No: TNU1019

6-Amino-4-chloropyrazolo[3,4-d]pyrimidine

Cat.No: TNU1018

4-Chloro-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0659

2,4-Dichloro-7H-pyrrolo[2,3-d]pyrimidine

Cat.No: T66608

4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0611

4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

Cat.No: T65517

4-Chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

Cat.No: T65530

5-(3-Bromo-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine

Cat.No: T64808

mTOR inhibitor 11

Cat.No: T9309

4-Chloro-5-iodo-7H-pyrrol[2,3-d]pyrimidine

Cat.No: TNU0717

2-[4-(Pyrimidin-2-yl)piperazin-1-yl]pyrimidine

Cat.No: T64531

Deoxycytidine triphosphate trisodium salt

Cat.No: T7518

Synonym: 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Antibiotic

5-Chloro-6-(chloromethyl)pyrimidine-2,4(1H,3H)-dione

Cat.No: T66943

4-Amino-6-bromo-5-cyano-7H-pyrrolo[2,3-d]pyrimidine

Cat.No: TNU1015

Ethyl 4-((4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylate

Cat.No: T66583

7-(2-Deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine

Cat.No: TNU1032

4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid

Cat.No: T66523

Cardiogenol C hydrochloride

Cat.No: T8005

Synonym: 2-[[2-[(4-甲氧基苯基)氨基]-4-嘧啶基]氨基]乙醇盐酸盐,Cardiogenol C HCl,Cardiogenol C

Target: Wnt/beta-catenin

4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0323

4,6-Diamino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU0280

6-Amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine

Cat.No: TNU1020

5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid

Cat.No: TNU1478

5-Carboxy-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidine acetic acid benzyl ester

Cat.No: TNU1477

Cat. No.	Product Name	Target	Signaling Pathways
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
T4746	Purine 7H-Imidazo(4,5-d)pyrimidine,嘌呤	Others; Endogenous Metabolite	Metabolism; Others
	Purine (7H-Imidazo(4,5-d)pyrimidine) 是内源性代谢产物的一种。
TN7191	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine 4-氨基-5-溴吡咯并[2,3-D]嘧啶,5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Others	Others
	4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine (5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine) 是一种海洋来源的天然产物，存在于Echinodictyum sp.。
T5078	Orotic acid monohydrate 2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate,乳清酸一水合物	Others; Endogenous Metabolite	Metabolism; Others
	Orotic acid monohydrate (2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate) 是内源性代谢产物的一种。
T7520	Deoxycytidine triphosphate	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Deoxycytidine triphosphate 是一种核苷三磷酸，是合成 DNA 的原料，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
T0746	Orotic acid 乳清酸,Vitamin B13,6-Carboxyuracil	Nucleoside Antimetabolite/Analog; Dehydrogenase; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Orotic acid (Vitamin B13) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T3271	Orotic acid zinc 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate	Nucleoside Antimetabolite/Analog; Others; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Others
	Orotic acid zinc (Zinc Orotate) 是一种嘧啶核苷酸和 RNA 生物合成的前体，从线粒体二氢乳清酸脱氢酶 (DHODH) 中释放，通过细胞质 UMP 合酶转化为 UMP。它可引起大鼠肝脂肪变性和肝肿大，是尿素循环异常的常规新生儿筛查中的一种测量指标。
T4711	2,4-Dihydroxypyrimidine-5-carboxylic acid 脲嘧啶-5-羧酸,Isoorotic acid,Uracil-5-carboxylic acid	Others; Endogenous Metabolite	Metabolism; Others
	2,4-Dihydroxypyrimidine-5-carboxylic acid (Isoorotic acid) 是内源性代谢产物的一种。
T0986	Flucytosine 5-Fluorocytosine,Ro 2-9915,5-氟胞嘧啶,Fluorocytosine,NSC 103805	DNA/RNA Synthesis; Antibiotic; Antifungal	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Flucytosine (NSC 103805) 是抗真菌化合物。
T5284	N-Carbamoyl-DL-aspartic acid 氨基甲酰-DL-天(门)冬氨酸,N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid,脲基琥珀酸	Others; Endogenous Metabolite	Metabolism; Others
	N-Carbamoyl-DL-aspartic acid (Ureidosuccinic acid) 是核酸嘧啶的前体之一。
T4887	3-Amino-2-methylpropanoic acid DL-3-AMINOISOBUTYRIC ACID,3-氨基异丁酸,α-Methyl-β-alanine	Endogenous Metabolite	Metabolism
	3-Amino-2-methylpropanoic acid (α-Methyl-β-alanine) 是 N-carbamyl-beta-aminoisobutyric acid 经 enzyme Beta-ureidopropionase (EC 3.5.1.6)转化后的产物，是嘧啶降解的最后一步。-尿嘧啶丙酸酶缺乏症是一种与神经异常相关的嘧啶降解的先天性错误。
T7457	5-Methyl-2'-deoxycytidine 5-Methyldeoxycytidine,5-甲基-2'-脱氧胞苷,5MedCyd	DNA Methyltransferase; Endogenous Metabolite	Chromatin/Epigenetic; Metabolism
	5-Methyl-2'-deoxycytidine (5MedCyd) 是嘧啶核苷，当掺入到单链 DNA 中时，可以顺式作用以从头发出信号。
TWO2759	Thymine 胸腺嘧啶,5-methyluracil	Others; Endogenous Metabolite	Metabolism; Others
	Thymine (5-methyluracil) 是 DNA 的四个碱基之一，在动物癌症模型中，能够作为5-氟尿嘧啶的靶标，其 Km=2.3 μM。
T4831	α,α-Dimethylglycine 2-Aminoisobutyric acid,α-Aminoisobutanoic acid,2-甲基丙氨酸	Others; Endogenous Metabolite	Metabolism; Others
	NSC-16590 (2-Aminoisobutyric acid) 对苍耳子叶中内源性乙烯(ethylene)的产生具有抑制作用。
TMA2440	Uridine 5'-monophosphate disodium salt 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate	Others	Others
	Uridine 5'-monophosphate disodium salt (Disodium UMP) 是合成 RNA 的一种重要成分。
T1591L	Cytidine Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Cytidine (Cytosine-1-β-D-ribofuranoside) 是一种嘧啶核苷，由通过 β-N1-糖苷键与核糖结合的胞嘧啶组成。它是尿苷的前体，用于 RNA 合成。
T5288	Cytidine-5'-triphosphate disodium 胞苷 5'-三磷酸二钠盐,CTP,Cytidine 5'-triphosphate (disodium salt)	Others; Endogenous Metabolite	Metabolism; Others
	Cytidine-5'-triphosphate disodium (CTP) 是内源性代谢产物的一种。
T4832	Cytosine 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine,胞嘧啶	Endogenous Metabolite	Metabolism
	Cytosine (6-Aminopyrimidin-2(1H)-one) 是 DNA 和 RNA 中发现的四个主要碱基之一。它修饰表现出与表观遗传多样性和衰老有关的昼夜节律振荡。
T0069	Uracil	Others; Endogenous Metabolite	Metabolism; Others
	Uracil 是普遍存在的天然嘧啶衍生物，是 RNA 核酸中的四个碱基之一。
T4919	Ureidopropionic acid Carbamoyl-b-alanine,3-酰脲丙酸,3-Ureidopropionic acid	Endogenous Metabolite	Metabolism
	Ureidopropionic acid (3-Ureidopropionic acid) 是尿嘧啶代谢的中间体。更具体地说，它是二氢尿嘧啶的分解产物，由二氢嘧啶酶产生。它通过β -脲丙酸酶进一步分解为β -丙氨酸。尿素丙酸本质上是β -丙氨酸的尿素衍生物。高水平的尿丙酸存在于β -尿丙酸酶(UP)缺乏的个体中。嘧啶代谢中的酶缺乏与抗肿瘤药物5-氟尿嘧啶的严重毒性风险有关。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine (Deoxyribose cytidine) 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
T4880	L-Dihydroorotic acid	Others; Endogenous Metabolite	Metabolism; Others
	L-Dihydroorotic acid 是一种能够通过二氢乳清酶，能够逆水解产生的无环 L-脲基琥珀酸。
T39626	Orotidine 5′-monophosphate Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate
	Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase.
T82682	Convicine
	Convicine为一种嘧啶糖苷，其与Vicine共同作为糖苷配基Divicine和Isouramil的前体。该化合物是蚕豆病的关键因素——一种因蚕豆摄入而触发的严重溶血遗传性疾病。Convicine能够从蚕豆中提取分离。
T75676	Orotidine 5′-monophosphate trisodium
	Orotidine 5'-monophosphate trisodium 是一种嘧啶核苷酸。Orotidine 5'-monophosphate trisodium 是通过从头合成途径合成的，用于在大量微生物中合成 DNA，包括 M. tuberculosis、S. cerevisiae、S. typhimurium 和 P. falciparum 等等。乳清酸磷酸核糖基转移酶 (OPRT) 以磷酸核糖焦磷酸 (PRPP) 和乳清酸 (OA) 作为底物催化合成 Orotidine 5'-monophosphate trisodium[1]

天然产物

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

Cat.No: T4746

Synonym: 7H-Imidazo(4,5-d)pyrimidine,嘌呤

Target: Others, Endogenous Metabolite

4-Amino-5-Bromopyrrolo[2,3-D]Pyrimidine

Cat.No: TN7191

Synonym: 4-氨基-5-溴吡咯并[2,3-D]嘧啶,5-bromo-1H-pyrrolo[2,3-d]pyrimidin-4-amine,5-bromo-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Target: Others

Orotic acid monohydrate

Cat.No: T5078

Synonym: 2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate,乳清酸一水合物

Target: Others, Endogenous Metabolite

Deoxycytidine triphosphate

Cat.No: T7520

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite

Cat.No: T0746

Synonym: 乳清酸,Vitamin B13,6-Carboxyuracil

Target: Nucleoside Antimetabolite/Analog, Dehydrogenase, Endogenous Metabolite

Orotic acid zinc

Cat.No: T3271

Synonym: 乳清酸锌二水合物,Orotic acid zinc salt dihydrate,Zinc Orotate

Target: Nucleoside Antimetabolite/Analog, Others, Endogenous Metabolite

2,4-Dihydroxypyrimidine-5-carboxylic acid

Cat.No: T4711

Synonym: 脲嘧啶-5-羧酸,Isoorotic acid,Uracil-5-carboxylic acid

Target: Others, Endogenous Metabolite

Cat.No: T0986

Synonym: 5-Fluorocytosine,Ro 2-9915,5-氟胞嘧啶,Fluorocytosine,NSC 103805

Target: DNA/RNA Synthesis, Antibiotic, Antifungal

N-Carbamoyl-DL-aspartic acid

Cat.No: T5284

Synonym: 氨基甲酰-DL-天(门)冬氨酸,N-Carbamoyl-DL-aspartic acid,Ureidosuccinic acid,脲基琥珀酸

Target: Others, Endogenous Metabolite

3-Amino-2-methylpropanoic acid

Cat.No: T4887

Synonym: DL-3-AMINOISOBUTYRIC ACID,3-氨基异丁酸,α-Methyl-β-alanine

Target: Endogenous Metabolite

5-Methyl-2'-deoxycytidine

Cat.No: T7457

Synonym: 5-Methyldeoxycytidine,5-甲基-2'-脱氧胞苷,5MedCyd

Target: DNA Methyltransferase, Endogenous Metabolite

Cat.No: TWO2759

Synonym: 胸腺嘧啶,5-methyluracil

Target: Others, Endogenous Metabolite

α,α-Dimethylglycine

Cat.No: T4831

Synonym: 2-Aminoisobutyric acid,α-Aminoisobutanoic acid,2-甲基丙氨酸

Target: Others, Endogenous Metabolite

Uridine 5'-monophosphate disodium salt

Cat.No: TMA2440

Synonym: 尿苷-5'-单磷酸二钠盐,Disodium UMP,尿苷酸二钠盐,Disodium uridine-5'-monophosphate,5'-UMP disodium salt,Disodium 5'-Uridylate

Target: Others

Cat.No: T1591L

Synonym: Cytosine-1-β-D-ribofuranoside,胞苷,Cytosine β-D-riboside

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cytidine-5'-triphosphate disodium

Cat.No: T5288

Synonym: 胞苷 5'-三磷酸二钠盐,CTP,Cytidine 5'-triphosphate (disodium salt)

Target: Others, Endogenous Metabolite

Cat.No: T4832

Synonym: 6-Aminopyrimidin-2(1H)-one,4-Amino-2-hydroxypyrimidine,Cytosinimine,胞嘧啶

Target: Endogenous Metabolite

Cat.No: T0069

Target: Others, Endogenous Metabolite

Ureidopropionic acid

Cat.No: T4919

Synonym: Carbamoyl-b-alanine,3-酰脲丙酸,3-Ureidopropionic acid

Target: Endogenous Metabolite

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

L-Dihydroorotic acid

Cat.No: T4880

Target: Others, Endogenous Metabolite

Orotidine 5′-monophosphate

Cat.No: T39626

Synonym: Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate

Cat.No: T82682

Orotidine 5′-monophosphate trisodium

Cat.No: T75676

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