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85

抑制剂 & 化合物

18

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14667	BLT-1	Others; HCV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	BLT-1 是一种氨基硫脲铜螯合剂，是一种选择性清除受体 B1 型 (SR-BI) 抑制剂，抑制高密度脂蛋白 (HDL) 和 SR-BI 介导的细胞之间的脂质转移。
T27460	GSK2324 GSK-2324,GSK 2324	FXR	Metabolism
	GSK2324 是一种有效的 FXR 激动剂，通过减少脂肪酸合成的吸收和选择性减少来控制肝脂质，可用于治疗非酒精性脂肪肝。
T25651	Lecimibide DuP128,DuP-128,DuP 128	Acyltransferase	Metabolism
	Lecimibide (DuP 128) 是一种有效且具有选择性的酰辅酶 A 胆固醇酰基转移酶(ACAT)抑制剂，可用于研究由于高脂带来的疾病。
T38604	C12-200 C12-200	Others	Others
	C12-200是一个基准的可离子化的阳离子类脂质与辅助类脂质一起，用于 mRNA 的传递。
TD0093	Oil Red O	Others	Others
	Oil Red O 用于制备染色溶液，可用于检测组织学冷冻切片中的脂质。
T37992	15-Methyl Palmitic Acid 15-Methylpalmitic acid,15-Methylhexadecanoic acid
	15-methyl Palmitic Acid 是一种一种甲基化脂肪酸，广泛存在于动物脂质中，可能于调节脂肪代谢有关。
T65133	3-Hydroxybutyric acid sodium β-Hydroxybutyric acid sodium
	3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) 是一种存在 I 型糖尿病患者体内的一种代谢物，具有调节膜脂的性质。
T9277	ALC-0315
	ALC-0315是一种可电离的氨基脂质，已与其他脂质组合用于形成脂质纳米颗粒。脂质纳米颗粒已经用于 mRNA (COVID-19) 疫苗的研究。
T33604	Z-Glycine Carbobenzoxyglycine,N-苄氧羰基-甘氨酸,N-Carbobenzoxyglycine	Others	Others
	Z-Glycine (Carbobenzoxyglycine) 是一种药物-脂质结合物，旨在促进脑渗透，基于其亲脂性和与生物膜中脂质的相似性。
T11086	DOTAP chloride (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride	Others	Others
	DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) 是高效的阳离子脂质，可以在不使用辅助脂质的情况下，作用于瞬时或者稳定转染 DNA (质粒、bacmids) 和修饰核酸 (反义寡核苷酸)。
T36013	Lysophosphatidylcholines Lyso-Lecithins (egg)	Apoptosis	Apoptosis
	Lysophosphatidylcholines (Lyso-Lecithins (egg)) 是一种具有口服活性的脂质，可诱导细胞损伤和凋亡 (apoptosis)，诱导脱髓鞘。Lysophosphatidylcholines 在炎症、纤维化和癌症的介导中发挥作用，可用于研究动脉粥样硬化。
T6267	Lomitapide AEGR-733,洛美他派,BMS-201038	CETP	Metabolism
	Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。
T5464	JNJ-10229570 JNJ10229570,UNII-N9IX402L35,JNJ 10229570	Melanocortin Receptor	GPCR/G Protein; Neuroscience
	JNJ-10229570 (UNII-N9IX402L35) 是肾上腺皮质受体 1 和肾上腺皮质受体 5 的拮抗剂，可抑制皮脂腺分化和皮质特异性脂质的产生，其抑制125I-NDP-α-MSH 和人类细胞中 MC1R 和 MC5R 结合的IC50值分别为 270 nM 和 200 nM。
T40588	Acifluorfen	Others	Others
	Acifluorfen 是一种除草剂。Acifluorfen 是一种原卟啉原氧化酶抑制剂，可促进原卟啉 IX 的积累，并诱导啮齿动物肝脏发生肿瘤。它会引起敏感植物物种中的色素和脂质强烈的光氧化破坏。
T9098	DMG-PEG 2000 DMG-PEG2000	Others	Others
	DMG-PEG 2000 (DMG-PEG2000) 可用于脂质纳米颗粒制备，用于口服质粒 DNA 的体内传递途径，提高纳米颗粒的黏液渗透性和传递效率。它也可用于 siRNA 转染的脂质体的制备，能够提高转染效率。
T36957	BODIPY 493/503 BDP 493/503 lipid stain,Pyrromethene 546	Others	Others
	BODIPY 493/503 (Pyrromethene 546) 是一种亲脂性荧光探针，Ex/Em 为 493/503 nm。 BODIPY 493/503 定位于极性脂质，可用于标记细胞中性脂质含量以及活细胞和固定细胞应用。
T19196	Arachidonyl alcohol	Others	Others
	Arachidonyl alcohol, a long-chain primary fatty alcohol, serves as a substrate for synthesizing various ether lipids with beneficial functions.
T29090	Valibose
	Valibose An α-glucosidase inhibitor. Valibose ameliorated metabolic disturbance of glucose and lipids. valibose markedly reduced level of serum BUN and NAG, and decreased the weight index of kidney.
T38249	2-Hydroxy atorvastatin lactone
	2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].
T10401	Atorvastatin acetonide	Others	Others
	Atorvastatin acetonide is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T11575	HS80	Others	Others
	HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids (IC50: 7.13 μM).
T20530	Cycloate HSDB 1712,R-2063,HSDB-1712,Etsan,R 2063,R2063
	Cycloate is a herbicide. It inhibits the biosynthesis of very-long-chain fatty acids, which is the essential constituents of plant suberin and waxes. Fatty acids also serve as precursors of aliphatic carbon chains in resorcinolic lipids.
T11574	HS79	Others	Others
	HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids (IC50: 1.57 μM).
T37399	15(S)-HETE methyl ester
	15(S)-HETE methyl ester is a synthetic derivative of 15(S)-HETE , a major arachidonic acid metabolite from the 15-lipoxygenase pathway. Methyl esters of lipids are commonly used in formulations of nutritional supplements.
T10127	(3R,5S)-Atorvastatin sodium	Others	Others
	(3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T82548	Dipyrrometheneboron difluoride
	Dipyrrometheneboron difluoride是一种绿色荧光染料，用于标记非极性脂质和检测钙。
T10120	3-Oxo Atorvastatin	Others	Others
	3-Oxo Atorvastatin is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T15099	Desfluoro-atorvastatin	Others	Others
	Desfluoro-atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active inhibitor of HMG-CoA reductase. It has the ability to effectively decrease blood lipids.
T38211	Monogalactosyl Diglyceride
	Monogalactosyl diglyceride is a minor galactolipid present in oligodendrocytes and myelin, as well as comprises a major fraction of the lipids in photosynthesizing plants and green microorganisms. [1][2] It is used as a marker for myelination and has also been shown to stimulate PKCα activity in oligodendrocytes. [2]
T12283	O-Methyl Atorvastatin hemicalcium	Others	Others
	O-Methyl Atorvastatin is an impurity of Atorvastatin that is an orally active inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, has the ability to effectively decrease blood lipids.
T31963	Glyco-lipid Glycolipid,Glyco lipid
	Glycolipids are lipids with a carbohydrate attached by a glycosidic (covalent) bond. Their role is to maintain the stability of the cell membrane and to facilitate cellular recognition, which is crucial to the immune response and in the connections that allow cells to connect to one another to form tissues.
T74288	SQDG
	SQDG 是一种膜脂，头部基团含有糖部分，用于研究结构脂在LNP制剂中的作用。
T61847	PptT-IN-2
	PptT-IN-2 (compound 5k) is a highly effective inhibitor of phosphopantetheinyl phosphoryl transferase (PptT), with an IC50 of 2.5 μM. PptT is an indispensable enzyme crucial for synthesizing cellular lipids and virulence factors in Mycobacterium tuberculosis. Therefore, PptT-IN-2 holds great promise for further investigations into tuberculosis research [1].
T15127	Difluoro atorvastatin Fluoroatorvastatin	Others	Others
	Difluoro atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active HMG-CoA reductase inhibitor and it has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion (IC50s: 0.39 μM and
T73841	9-PAHPA
	9-PAHPA，一种羟基脂肪酸的脂肪酸酯 (FAHFA)，属于一类新的内源性脂质家族，显示出抗糖尿病和抗炎特性。
T35620	Ethoxyquin Dimer
	Ethoxyquin dimer is an antioxidant and metabolite of ethoxyquin .1 It prevents oxidation of polyunsaturated fatty acids in fish meal and fish oil. Dietary administration of ethoxyquin dimer (0.1, 0.3, and 0.5% w/w) induces microvesicular steatosis and hepatocyte necrosis, as well as increases liver levels of oxidized glutathione and total lipids in mice.2
T68948	Detorubicin HCl
	Detorubicin is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin.
T10399	Atorvastatin 3-Deoxyhept-2E-Enoic Acid (2E)-2,3-Dehydroxy Atorvastatin	Others	Others
	Atorvastatin 3-Deoxyhept-2E-Enoic Acid is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T74421	Pemvidutide
	Pemvidutide 是一种GLP-1R/GCGR 双重激动剂，可导致体重、肝脏脂肪和血清脂质的显著降低。Pemvidutide 可用于非酒精性脂肪性肝炎 (NASH) 和肥胖症的研究。
T61167	PptT-IN-1
	PptT-IN-1 (compound 5j) is a highly potent inhibitor (IC50: 2.8 μM) of phosphopantetheinyl phosphoryl transferase (PptT), a crucial enzyme involved in the biosynthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound shows considerable potential for tuberculosis research [1].
T30484	Blennin C Lactaronecatorin A
	Blennin C, also known as Lactaronecatorin A, belongs to the class of organic compounds known as terpene lactones. These are prenol lipids containing a lactone ring. Within the cell, lactaronecatorin is primarily located in the membrane (predicted from log
T61466	PptT-IN-3
	PptT-IN-3 (compound 5p) is a powerful inhibitor (IC 50 = 3.5 μM) of phosphopantetheinyl phosphoryl transferase (PptT), an indispensable enzyme involved in the synthesis of cellular lipids and virulence factors in Mycobacterium tuberculosis. This compound, PptT-IN-3, holds promise for tuberculosis research [1].
T82043	Iso5-2DC18
	Iso5-2DC18是用于合成含胺脂质的化合物。该脂质适用于mRNA传递、激活STING通路及表达抗肿瘤免疫效应。
T70978	5-Hydroxy Lansoprazole Sulfide
	5-Hydroxy Lansoprazole Sulfide is an inhibitor of fatty acid synthase (FASN). FASN, which is responsible for de-novo synthesis of lipids, has been found to be overexpressed in cancerous tissue. 5-Hydroxy Lansoprazole Sulfide specifically inhibits enoyl reductase, and was found to more effectively inhibit FASN function than lansoprazole and was also more efficient at regulating NHEJ repair of oxidative DNA damage via PARP1.
T36450	1,2-Dimyristoyl-rac-glycerol
	1,2-Dimyristoyl-rac-glycerol 可促进蛋白质和脂质之间的相互作用，可用作洗涤剂或试剂。可用于甘油脂的代谢和代谢途径的细胞生物学实验等。
T68909	Detorubicin Free Base
	Detorubicin Free Base is a semi-synthetic derivative of the anthracycline antineoplastic antibiotic daunorubicin. Detorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation. Detorubicin is less toxic than daunorubicin.
T72101	Atorvastatin hemicalcium trihydrate 阿托伐他汀半钙三水合物,阿托他伐汀半钙三水合物
	Atorvastatin hemicalcium trihydrate 是一种具有口服活性的 HMG-CoA 还原酶抑制剂，具有有效降低血脂的能力。Atorvastatin hemicalcium trihydrate 以 IC50值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。
T34807	Terephthalamidine terephthalimidamide
	Terephthalamidine is a derivative of the phthalanilide compounds. Terephthalamidine belongs to a family of compounds which appear to reversibly bind to the minor groove of the DNA double helix but not intercalate DNA. This agent also has been suggested to
T77264	Thiocholesterol
	Thiocholesterol 是一种胆固醇衍生物，常用于合成阳离子脂质液态晶体 (CLCs)。它也作为纳米银 (SNP) 的有效稳定剂。此外，Thiocholesterol 在质膜研究和药物递送领域有重要应用。
T76098	Glycerol-3-phosphate oxidase
	Glycerol-3-phosphate oxidase，即磷酸甘油氧化酶，是甘油代谢的关键中间体。Glycerol-3-phosphate oxidase 能够从大肠杆菌中提取得到。Glycerol-3-phosphate oxidase 是膜脂质的磷脂的骨架，也是呼吸链的底物。Glycerol-3-phosphate oxidase 通过氧化产生电子。

化合物

Cat.No: T14667

Target: Others, HCV Protease

Cat.No: T27460

Synonym: GSK-2324,GSK 2324

Target: FXR

Cat.No: T25651

Synonym: DuP128,DuP-128,DuP 128

Target: Acyltransferase

Cat.No: T38604

Synonym: C12-200

Target: Others

Cat.No: TD0093

Target: Others

15-Methyl Palmitic Acid

Cat.No: T37992

Synonym: 15-Methylpalmitic acid,15-Methylhexadecanoic acid

3-Hydroxybutyric acid sodium

Cat.No: T65133

Synonym: β-Hydroxybutyric acid sodium

Cat.No: T9277

Cat.No: T33604

Synonym: Carbobenzoxyglycine,N-苄氧羰基-甘氨酸,N-Carbobenzoxyglycine

Target: Others

Cat.No: T11086

Synonym: (2,3-二油氧基丙基)三甲基氯化铵,1,2-Dioleoyl-3-trimethylammonium-propane chloride

Target: Others

Lysophosphatidylcholines

Cat.No: T36013

Synonym: Lyso-Lecithins (egg)

Target: Apoptosis

Cat.No: T6267

Synonym: AEGR-733,洛美他派,BMS-201038

Target: CETP

Cat.No: T5464

Synonym: JNJ10229570,UNII-N9IX402L35,JNJ 10229570

Target: Melanocortin Receptor

Cat.No: T40588

Target: Others

Cat.No: T9098

Synonym: DMG-PEG2000

Target: Others

Cat.No: T36957

Synonym: BDP 493/503 lipid stain,Pyrromethene 546

Target: Others

Arachidonyl alcohol

Cat.No: T19196

Target: Others

Cat.No: T29090

2-Hydroxy atorvastatin lactone

Cat.No: T38249

Atorvastatin acetonide

Cat.No: T10401

Target: Others

Cat.No: T11575

Target: Others

Cat.No: T20530

Synonym: HSDB 1712,R-2063,HSDB-1712,Etsan,R 2063,R2063

Cat.No: T11574

Target: Others

15(S)-HETE methyl ester

Cat.No: T37399

(3R,5S)-Atorvastatin sodium

Cat.No: T10127

Target: Others

Dipyrrometheneboron difluoride

Cat.No: T82548

3-Oxo Atorvastatin

Cat.No: T10120

Target: Others

Desfluoro-atorvastatin

Cat.No: T15099

Target: Others

Monogalactosyl Diglyceride

Cat.No: T38211

O-Methyl Atorvastatin hemicalcium

Cat.No: T12283

Target: Others

Cat.No: T31963

Synonym: Glycolipid,Glyco lipid

Cat.No: T74288

Cat.No: T61847

Difluoro atorvastatin

Cat.No: T15127

Synonym: Fluoroatorvastatin

Target: Others

Cat.No: T73841

Ethoxyquin Dimer

Cat.No: T35620

Detorubicin HCl

Cat.No: T68948

Atorvastatin 3-Deoxyhept-2E-Enoic Acid

Cat.No: T10399

Synonym: (2E)-2,3-Dehydroxy Atorvastatin

Target: Others

Cat.No: T74421

Cat.No: T61167

Cat.No: T30484

Synonym: Lactaronecatorin A

Cat.No: T61466

Cat.No: T82043

5-Hydroxy Lansoprazole Sulfide

Cat.No: T70978

1,2-Dimyristoyl-rac-glycerol

Cat.No: T36450

Detorubicin Free Base

Cat.No: T68909

Atorvastatin hemicalcium trihydrate

Cat.No: T72101

Synonym: 阿托伐他汀半钙三水合物,阿托他伐汀半钙三水合物

Terephthalamidine

Cat.No: T34807

Synonym: terephthalimidamide

Thiocholesterol

Cat.No: T77264

Glycerol-3-phosphate oxidase

Cat.No: T76098

Cat. No.	Product Name	Target	Signaling Pathways
T4947	3-Hydroxybutyric acid Butanoic acid,3-羟基丁酸	Endogenous Metabolite	Metabolism
	3-Hydroxybutyric acid (Butanoic acid) 是一种人内源性代谢物，在 I 型糖尿病中升高。它能够调节膜脂的性质。
T6S0117	Avicularin Fenicularin,扁蓄苷	ERK	MAPK
	Avicularin (Fenicularin) 具有抗过敏、抗炎、保肝、抗氧化、抗肿瘤等活性。它能通过调节 NF-κB(p65)、COX-2 和 PPAR-γ 的活性来改善人类肝细胞癌。在 LPS 刺激的 RAW 264.7 巨噬细胞中，它通过抑制 ERK 信号通路产生抗炎活性。
T38141	Glycerophospholipids, cephalins Phosphatidylethanolamines (egg)
	Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物，在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用，可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
TQ0154	8-Hydroxyguanosine	Others; Endogenous Metabolite	Metabolism; Others
	8-Hydroxyguanosine 是氧化应激的系统标记，也是氢氧自由基对 RNA 损伤的标记。
TN1274	4-Allylcatechol 2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol	Others	Others
	4-Allylcatechol (Hydroxychavicol) 是合成黄樟素的一种中间体。
TN2364	Sudan IV 苏丹红Ⅳ,Solvent Red 24,C.I. 26105	Others	Others
	Sudan IV (Solvent Red 24) 是脂溶性重氮染料，可用于冰冻或石蜡切片上，能够将脂类、甘油三酯和脂蛋白染色。
T5258	Dodecanedioic acid diammonium salt 十二烷二酸二铵盐,1,10-Decanedicarboxylic acid diammonium salt	Others	Others
	Dodecanedioic acid diammonium salt (1,10-Decanedicarboxylic acid diammonium salt) 是一种二元羧酸，它是水溶性的，并且参与了脂类和碳水化合物的代谢途径中间体。
T5295	1-Hydroxyoctadecane 硬脂醇,1-Octadecanol,Stearyl alcohol,Octadecanol	Others; Endogenous Metabolite	Metabolism; Others
	1-Hydroxyoctadecane (OctadecanolOctadecanol) 是内源性代谢产物的一种。
T0429	Glucosamine Chitosamine,D-Glucosamine,氨基葡萄糖,葡糖胺	MMP; Others; TNF; NF-κB; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; CFTR; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; NF-κB; Others; Proteases/Proteasome
	Glucosamine (Chitosamine) 是软骨基质和滑液中糖胺聚糖的天然成分，常用作骨关节炎的治疗方法。它也是一种氨基糖，是糖基化蛋白和脂质生化合成的突出前体，用作膳食补充剂。
T2A2509	Laurocapram 月桂氮酮,Tranzone,Azone,N-Lauryl caprolactam,N-0252,月桂氮卓酮,N-Dodecylcaprolactam	Others	Others
	Laurocapram (N-Lauryl caprolactam) 是吸收促进剂，对于亲脂性和亲水性物质都是一种最有效的吸收剂。
T9279	nerolidol acetate	Others	Others
	Nerolidol acetate是一种具有抗癌、抗炎、抗菌和抗虫的活性的天然倍半萜。Nerolidol acetate可抑制寄生虫活动，抑制吸血虫病、线虫病以及疟疾等。Nerolidol acetate可保护细胞免受脂质、蛋白质和 DNA 的氧化损伤，对小鼠海马神经细胞具有保护作用。
T6480	D-Pantothenic acid vitamin B5,pantothenate,D-泛酸	Others	Others
	D-Pantothenic acid (vitamin B5) 是必需的微量营养素，是辅酶 A 的前体，在很多生物过程中发挥关键作用，如调节碳水化合物，脂质，蛋白和核酸代谢。
T4809	Pyrimidine 嘧啶,Metadiazine	Others; Endogenous Metabolite	Metabolism; Others
	Pyrimidine (Metadiazine) 是内源性代谢产物的一种。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T4889	2,6-Diaminoheptanedioic acid	Others; Endogenous Metabolite	Metabolism; Others
	2,6-Diaminoheptanedioic acid 是内源性代谢产物的一种。
T2163	Dihydrocapsaicin CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide	Others; TRP/TRPV Channel	Membrane transporter/Ion channel; Others
	Dihydrocapsaicin (CCRIS1589) 是一种天然来源的辣椒素，是TRPV1的选择性激动剂，同时可以增加 p-Akt 水平。它可以增强低温诱导的神经保护。
T37219	N-Palmitoyl Glycine
	The acyl amides are a family of endogenous lipids that act as potent modulators of pain and inflammation. The best characterized members of this family are the arachidonoyl amides, which includes N-arachidonoyl ethanolamide (AEA; anandamide). N-palmitoyl glycine (PalGly) contains an 18-carbon saturated fatty acid that is amide-linked to glycine and is structurally similar to the phospholipid-derived N-acyl ethanolamines. Endogenously produced in rat skin and spinal cord, PalGly is present in 100...
T36563	(E)-Guggulsterone
	Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy...

天然产物

3-Hydroxybutyric acid

Cat.No: T4947

Synonym: Butanoic acid,3-羟基丁酸

Target: Endogenous Metabolite

Cat.No: T6S0117

Synonym: Fenicularin,扁蓄苷

Target: ERK

Glycerophospholipids, cephalins

Cat.No: T38141

Synonym: Phosphatidylethanolamines (egg)

8-Hydroxyguanosine

Cat.No: TQ0154

Target: Others, Endogenous Metabolite

4-Allylcatechol

Cat.No: TN1274

Synonym: 2-羟基胡椒酚,4-Allylpyrocatechol,Hydroxychavicol

Target: Others

Cat.No: TN2364

Synonym: 苏丹红Ⅳ,Solvent Red 24,C.I. 26105

Target: Others

Dodecanedioic acid diammonium salt

Cat.No: T5258

Synonym: 十二烷二酸二铵盐,1,10-Decanedicarboxylic acid diammonium salt

Target: Others

1-Hydroxyoctadecane

Cat.No: T5295

Synonym: 硬脂醇,1-Octadecanol,Stearyl alcohol,Octadecanol

Target: Others, Endogenous Metabolite

Cat.No: T0429

Synonym: Chitosamine,D-Glucosamine,氨基葡萄糖,葡糖胺

Target: MMP, Others, TNF, NF-κB, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, CFTR, Autophagy

Cat.No: T2A2509

Synonym: 月桂氮酮,Tranzone,Azone,N-Lauryl caprolactam,N-0252,月桂氮卓酮,N-Dodecylcaprolactam

Target: Others

nerolidol acetate

Cat.No: T9279

Target: Others

D-Pantothenic acid

Cat.No: T6480

Synonym: vitamin B5,pantothenate,D-泛酸

Target: Others

Cat.No: T4809

Synonym: 嘧啶,Metadiazine

Target: Others, Endogenous Metabolite

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

2,6-Diaminoheptanedioic acid

Cat.No: T4889

Target: Others, Endogenous Metabolite

Dihydrocapsaicin

Cat.No: T2163

Synonym: CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Target: Others, TRP/TRPV Channel

N-Palmitoyl Glycine

Cat.No: T37219

(E)-Guggulsterone

Cat.No: T36563

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