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Search Results for " diphosphate "

117

抑制剂 & 化合物

28

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T15727	Sonidegib diphosphate NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate	Smo	Stem Cells
	Sonidegib diphosphate (LDE225 diphosphate) 是 Smo 的选择性拮抗剂，能够抑制鼠 Smo (IC50:1.3 nM)和人 Smo (IC50:2.5 nM)。
T2691	Oritavancin diphosphate 奥利万星二磷酸盐,LY333328 diphosphate	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Oritavancin diphosphate (LY333328 diphosphate) 是一种新型半合成的糖肽抗生素, 可研究革兰氏阳性菌感染。
T31163	Cytidine 5'-diphosphate disodium CDP sodium salt,Cytidine 5'-diphosphate disodium salt,胞苷-5'-二磷酸二钠盐,Cytidine diphosphate sodium salt	Others	Others
	Cytidine 5'-diphosphate disodium (CDP sodium salt) 产生 CTP 以支持 DNA 和 RNA 生物合成和核糖核苷酸还原酶以产生 dCMP。
T2288L	Motesanib Diphosphate Motesanib,AMG 706,二磷酸莫替沙尼	VEGFR; c-Kit	Angiogenesis; Tyrosine Kinase/Adaptors
	Motesanib Diphosphate (AMG 706) 是一种有效的VEGFR1/2/3的 ATP 竞争性抑制剂，IC50值为 2 nM/3 nM/6 nM，与对 Kit 的选择性相似，是 PDGFR 和 Ret 的 10 倍多。
T0850	Primaquine diphosphate Primaquine phosphate,磷酸伯氨喹,Primaquine bisphosphate,磷酸伯安喹	Antibiotic; Parasite	Microbiology/Virology
	Primaquine diphosphate 是一种合成的 8-氨基喹啉衍生物，具有抗疟特性。它是一种能破坏间日疟原虫和卵形疟原虫肝脏晚期和潜在组织形态的化合物。
T7606	Guanosine 5'-diphosphate disodium salt 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐	Endogenous Metabolite	Metabolism
	Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) 是一种核苷二磷酸。它是一种潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用，也可以调节白 IL-6/stat-3 途径。
T13284	Vapendavir diphosphate BTA798 diphosphate	Others	Others
	Vapendavir diphosphate is a potent enteroviral capsid binder (CB) and has a potent antiviral activity for enterovirus 71 (EV71) replication (EC50: 0.5-1.4 μM in different EV71 strains).
T20421	Fluorescein diphosphate Fluorescein diphosphate Tetraammonium salt,FDP
	Fluorescein diphosphate is a colorless and nonfluorescent substrate for alkaline phosphatases. The sequential alkaline phosphatase mediated hydrolysis of its two phosphate substituents yielding weakly fluorescent fluorescein monophosphate followed by stro
T78669	(1R,4S)-Yimitasvir diphosphate (1R,4S)-DAG-181 diphosphate,(1R,4S)-Emitasvir diphosphate
	Yimitasvir (Emitasvir) diphosphate是一口服活性HCV NS5A抑制剂，适用于研究慢性丙型肝炎病毒感染。
T37909	Tenofovir diphosphate
	Tenofovir diphosphate (TFV-DP) is a competitive inhibitor of DNA polymerases, specifically targeting dATP, and it serves as a substrate for the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1)[1].
T38570	DMAPP triammonium Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt	Others	Others
	DMAPP triammonium (Dimethylallyl diphosphate triammonium) 是一种异戊二烯类化合物的前提物质之一，参与甲羟戊酸 (MVA) 途径，可用于研究与代谢相关的疾病。
T37910	Tenofovir diphosphate triethylamine
	Tenofovir diphosphate triethylamine (TFV-DP triethylamine) is a competitive inhibitor of DNA polymerases for dATP, functioning as a substrate for HIV type 1 reverse transcriptase (HIV-1 RT)[1].
T8735	Sulbactum Sodium 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸	Others	Others
	Sulbactum Sodium (5'-CDP) 由胞苷一磷酸 (CMP) 或尿苷一磷酸 (UMP) 通过磷酸基团的转移在尿苷酸激酶 (UMPK) 酶的催化下合成。
T36880	NHC-diphosphate
	NHC-diphosphate is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a diphosphate form[1]. NHC is a pyrimidine ribonucleoside and behaves as a potent anti-virus agent. NHC effectively inhibits the replication of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV)[1]. Huh-7 cells are incubated with (10-50 μM; 4 h) NHC or a McGuigan phosphoramidate prodrug of NHC.Intracellular levels of the parental compounds and ...
T36881	NHC-diphosphate triammonium
	NHC-triphosphate triammonium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) as a triphosphate form[1]. NHC-triphosphate triammonium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA[1][2]. In an intracellular metabolism assay, HCV replicon cells are treated with 10 μM 3H-labeled NHC, and intracellular nucleotide levels are determined after 1, 2 and 8 hours incubations. NHC is rapidly convered into the mono...
T29990	Aminoquinol diphosphate
	Aminoquinol diphosphate may be useful in the treatment of acute necrotising cutaneous leishmaniasis.
T12354L	Oxythiamine diphosphate	Others	Others
	Oxythiamine diphosphate is a competitivethiamine pyrophosphate inhibitor(Ki of 30 nM).
T68551	Cabergoline diphosphate
	Cabergoline diphosphate is a dopamine D2 receptor agonist used for prolactinoma treatment. Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
T37523	Tenofovir diphosphate (sodium salt)
	Tenofovir diphosphate is an inhibitor of HIV reverse transcriptase (Kis = 0.022 and 1.55 μM for RNA and DNA, respectively) and hepatitis B virus (HBV) polymerase (Ki = 0.18 μM). It is selective for these enzymes over DNA polymerase α and β, as well as mitochondrial DNA polymerase γ (Kis = 5.2, 81.7, and 59.5 μM, respectively). Tenofovir diphosphate is formed intracellularly through phosphorylation of the prodrugs tenofovir and tenofovir disoproxil by nucleotide kinases. Increased levels of tenof...
T83813	8-Azidoadenosine-5'-O-diphosphate sodium 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate
	8-Azidoadenosine-5'-O-diphosphate（8-azido-ADP）是ATP前体和嘌呤受体配体ADP的可点击形式。8-azido-ADP的放射性标记形式已被用作各种蛋白质的光亲和标签，包括从牛脑中分离的谷氨酸脱氢酶（GDH）同工酶，以及从兔网织红细胞中分离的真核翻译起始因子2（eIF2）和鸟苷核苷酸交换因子（GEF）。
T37154	7-Methylguanosine 5'-diphosphate sodium
	7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1]. 7-Methylguanosine 5’-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5’-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2]. [1]. Sonenberg N, et al. Nonspecific effect o...
T71518	Zidovudine diphosphate
	Zidovudine diphosphate is an antiretroviral medication used to prevent and treat HIV/AIDS. It is of the nucleoside analog reverse-transcriptase inhibitor (NRTI) class. Zidovudine inhibits the enzyme (reverse transcriptase) that HIV uses to synthesize DNA, thus preventing viral DNA from forming.
T71609	Hexestrol diphosphate sodium
	Hexestrol diphosphate sodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation.
T36740	Guanosine 5’-diphosphate (sodium salt hydrate)
	Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells in a patch-clamp assay.3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Biochemistry(2002) 2.Vetter, I.R., and Wittinghofer, A.The guanine nucleotide-binding switch in three dimensionsScience294(5545)...
T70251	Hexestrol diphosphate tetrasodium
	Hexestrol diphosphate tetrasodium is a synthetic ER agonist, microtubule polymerization inhibitor, and potential carcinogen. It induces mitotic arrest, aneuploidy, and DNA adduct formation.
T11001L	Desethyl chloroquine diphosphate	Others	Others
	Desethyl chloroquine diphosphate is the main deethyl metabolite of chloroquine. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Chloroquine diphosphate has anti-plasma activity.
T72120	Guanosine 5'-diphosphate sodium GDP sodium
	Guanosine 5'-diphosphate (GDP) sodium 是一种核苷二磷酸，可激活 5'-三磷酸腺苷敏感的 K+通道。Guanosine 5'-diphosphate sodium 是一种潜在的铁动员剂，可阻断铁调素-铁转运蛋白 (hepcidin-ferroportin) 相互作用并调节 IL-6/stat-3通路。Guanosine 5'-diphosphate sodium 可用于炎症研究，如炎症性贫血 (AI)。
T26648	Arabinose 1,5-diphosphate
	Arabinose 1,5-diphosphate is a bisphosphatase inhibitor.
T32764	Linear-benzoadenosine diphosphate Lin-benzo-ADP
	Linear-benzoadenosine diphosphate is a nucleotide analog.
T83821	Thymidine-5'-O-(α,β-methylene)diphosphate sodium α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP
	TMP-CP（Thymidine-5’-O-(α,β-methylene)diphosphate）是TDP的一种水解稳定衍生物，同时也是一种thymidine kinase抑制剂（Ki = 23 µM）。它已被用作α,β-methylene-2’-deoxythymidine 5’-triphosphate合成的前体，该合成物是DNA polymerase的一种不可切割底物。
T19579	Thiamine diphosphate analog 1	Others	Others
	Thiamine diphosphate analog 1, an analog of Thiamine diphosphate (the active form of vitamin B1 and a universal cofactor in key cellular pathways), mirrors the structure and potentially the function of its prototype.
T71927	Adenosine-5'-diphosphate disodium salt
	Adenosine 5'-diphosphate disodium salt has been shown to inhibit the binding of serotonin (5-hydroxytryptamine) to 5-HT2 receptors, which are present in heart tissue.
T37057	D-myo-Inositol-1,2-diphosphate (sodium salt)
	Ins(1,2)P2 (sodium salt) is one of the many inositol phosphate (InsP) isomers that could act as small, soluble second messengers in the transmission of cellular signals. The most studied InsP Ins(1,4,5)P3, is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in intracellular calcium. Ins(1,2)P2 (te...
T37060	D-myo-Inositol-1,3-diphosphate (sodium salt)
	D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to its receptor on the endoplasmic reticulum results in opening of the calcium channels and an increase in in...
T23581	2-Methylthioadenosine diphosphate trisodium 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP
	2-MeS-ADP is a purinergic agonist that acts by displaying selectivity for P2Y1, P2Y12, and P2Y13 receptors and inhibiting cAMP accumulation.
T36973	5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)
	5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several phosphoribosyltransferases (PRTases) use PRPP as a substrate to add a 5-phosphoribosyl group to another substrate, as in the production of adenosine monophosphate from adenine and PRPP by adenine PRTase. N/A
T74588	Yimitasvir diphosphate
	Yimitasvir (Emitasvir) diphosphate，一种针对丙型肝炎病毒(HCV)非结构蛋白5A (NS5A)的口服活性抑制剂，适用于慢性丙型肝炎病毒感染的研究。
T72182	Combretastatin A1 phosphate Oxi4503,CA1P,Oxi4503 ; CA1P ; Combretastatin A1 diphosphate,Combretastatin A1 diphosphate
	Combretastatin A1 phosphate 是一种有效的血管破坏剂。Combretastatin A1 phosphate 对肿瘤具有抗血管生成作用。Combretastatin A1 phosphate 具有用于胰腺神经内分泌肿瘤研究的潜力。
T35572	Adenosine 3',5'-diphosphate sodium salt 3'-Phosphoadenosine 5'-phosphate	Endogenous Metabolite	Metabolism
	Adenosine 3',5'-diphosphate sodium salt 是一种羟类固醇磺基转移酶 (hydroxysteroid sulfotransferases) 抑制剂，是一种腺嘌呤核苷酸，在戊糖核糖的 3'和 5'位置含有一个磷酸基团。Adenosine 3',5'-diphosphate (sodium salt)是 3'-phosphoadenosine 5'-phosphosulfonate (PAPS) 的产物，是磺基转移酶（SULTs）的辅助因子，已被用于研究 SULTs 的动力学特性和结构。
T78081	Farnesyl Pyrophosphate ammonium Farnesyl diphosphate ammonium
	Farnesyl pyrophosphate ammonium salt为15碳类异戊二烯代谢中间体，源自MVA途径，兼具TRPM2激动剂功能，能够触发TRPM2通道开放并促进离子流入细胞。它亦是胆固醇合成、泛醌合成、蛋白质法尼基化修饰以及GGPP合成的关键底物。
T73807	Geranyl diphosphate
	Geranyl diphosphate 是IBP(类异戊二烯生物合成途径)的关键中间体，在细胞代谢中扮演至关重要的角色，主要负责甾醇和非甾醇类异戊二烯的生成。
T69264	Aristeromycin diphosphate
	Aristeromycin diphosphate is an inhibitor of S-adenosylhomocysteine hydrolase (AHCY), inducing miR-26a and regulating oncogenic EZH2 expression, showing high inhibitory activity against AHCY, and causing growth inhibition of prostate cancer.
T64282	Oxythiamine diphosphate ammonium
	Oxythiamin diphosphate ammonium 是一种转酮酶 (TK) 的有效抑制剂。
T73983	Cidofovir diphosphate tri(triethylamine)
	Cidofovir diphosphate tri triethylamine 是西多福韦的细胞内活性代谢物。diphosphate tri triethylamine 是病毒 DNA 聚合酶的选择性抑制剂，对 HCMV，HSV-1和 HSV-2的 Ki 值分别为 6.6，0.86 和 1.4 μM。
T78583	Uridine 5'-diphosphate	P2Y Receptor	GPCR/G Protein; Neuroscience
	Uridine 5'-diphosphate 作为P2Y6受体激动剂，具有针对人P2Y6受体0.013 μM的EC50。
T73980	Thymidine 5′-diphosphate
	Thymidine 5′-diphosphate (dTDP) 是合成嘧啶的关键产物，通过胸苷酸激酶 (TMPK) 对 5'-单磷酸胸苷 (dTMP) 进行磷酸化反应生成，此过程需 ATP 与 Mg2+。进一步，dTDP 可被 TMPK 催化转化为胸苷 5'-三磷酸 (dTTP)。通过测量 dTDP 水平，可以评估 TMPK 活性。
T12008	MethADP Adenosine 5'-(α,β-methylene)diphosphate	Others	Others
	MethADP is a specific inhibitor of CD73.
T29296	1-Deaza-fad Deazafad,5-Deazariboflavin-5'-diphosphate,1-deazaFAD
	1-Deaza-fad also known as Deazafad. 1-deazaFAD has comparable activity in the mutase reconstituted.
T73899	Uridine diphosphate glucuronic acid ammonium
	Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium 是一种由 UDP-葡萄糖脱氢酶催化生成的辅助因子，属于糖核苷酸生物合成的关键前体。它不仅是 C4 表聚酶和脱羧酶释放 UDP-半乳糖醛酸(UDP-GalA)和 UDP-戊糖产物的共同底物，而且作为葡萄糖醛酸供体，在胆红素在内质直肠结合的研究中有重要应用。
T73824	Thymidine 3',5'-diphosphate tetrasodium
	Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium，为一种选择性抑制剂，主要针对葡萄球菌核酸酶及含1的都铎结构域(SND1，MicroRNA调控复合体RISC亚基)和[3,5-2H2]酪氨酸核酸酶([3,5-2H2] tyrosyl nuclease)。此化合物还展示了抗肿瘤活性，并可在生化反应中作为催化剂使用。

化合物

Sonidegib diphosphate

Cat.No: T15727

Synonym: NVP-LDE 225 diphosphate,Erismodegib diphosphate,LDE225 diphosphate

Target: Smo

Oritavancin diphosphate

Cat.No: T2691

Synonym: 奥利万星二磷酸盐,LY333328 diphosphate

Target: Others, Antibacterial, Antibiotic

Cytidine 5'-diphosphate disodium

Cat.No: T31163

Synonym: CDP sodium salt,Cytidine 5'-diphosphate disodium salt,胞苷-5'-二磷酸二钠盐,Cytidine diphosphate sodium salt

Target: Others

Motesanib Diphosphate

Cat.No: T2288L

Synonym: Motesanib,AMG 706,二磷酸莫替沙尼

Target: VEGFR, c-Kit

Primaquine diphosphate

Cat.No: T0850

Synonym: Primaquine phosphate,磷酸伯氨喹,Primaquine bisphosphate,磷酸伯安喹

Target: Antibiotic, Parasite

Guanosine 5'-diphosphate disodium salt

Cat.No: T7606

Synonym: 5'-二磷酸鸟苷二钠,5'-GDP-Na2,鸟苷-5'-二磷酸二钠盐

Target: Endogenous Metabolite

Vapendavir diphosphate

Cat.No: T13284

Synonym: BTA798 diphosphate

Target: Others

Fluorescein diphosphate

Cat.No: T20421

Synonym: Fluorescein diphosphate Tetraammonium salt,FDP

(1R,4S)-Yimitasvir diphosphate

Cat.No: T78669

Synonym: (1R,4S)-DAG-181 diphosphate,(1R,4S)-Emitasvir diphosphate

Tenofovir diphosphate

Cat.No: T37909

DMAPP triammonium

Cat.No: T38570

Synonym: Dimethylallyl diphosphate triammonium,Dimethylallyl Pyrophosphate triammonium salt

Target: Others

Tenofovir diphosphate triethylamine

Cat.No: T37910

Sulbactum Sodium

Cat.No: T8735

Synonym: 5'-CDP,Cytidine-5′-diphosphate,胞苷-5'-二磷酸

Target: Others

NHC-diphosphate

Cat.No: T36880

NHC-diphosphate triammonium

Cat.No: T36881

Aminoquinol diphosphate

Cat.No: T29990

Oxythiamine diphosphate

Cat.No: T12354L

Target: Others

Cabergoline diphosphate

Cat.No: T68551

Tenofovir diphosphate (sodium salt)

Cat.No: T37523

8-Azidoadenosine-5'-O-diphosphate sodium

Cat.No: T83813

Synonym: 8-azido-ADP,Click Tag™ 8-Azidoadenosine-5'-O-diphosphate

7-Methylguanosine 5'-diphosphate sodium

Cat.No: T37154

Zidovudine diphosphate

Cat.No: T71518

Hexestrol diphosphate sodium

Cat.No: T71609

Guanosine 5’-diphosphate (sodium salt hydrate)

Cat.No: T36740

Hexestrol diphosphate tetrasodium

Cat.No: T70251

Desethyl chloroquine diphosphate

Cat.No: T11001L

Target: Others

Guanosine 5'-diphosphate sodium

Cat.No: T72120

Synonym: GDP sodium

Arabinose 1,5-diphosphate

Cat.No: T26648

Linear-benzoadenosine diphosphate

Cat.No: T32764

Synonym: Lin-benzo-ADP

Thymidine-5'-O-(α,β-methylene)diphosphate sodium

Cat.No: T83821

Synonym: α,β-Methylenethymidine diphosphate,Thymidine-5'-O-methylenediphosphate,TMP-CP,α,β-MTDP

Thiamine diphosphate analog 1

Cat.No: T19579

Target: Others

Adenosine-5'-diphosphate disodium salt

Cat.No: T71927

D-myo-Inositol-1,2-diphosphate (sodium salt)

Cat.No: T37057

D-myo-Inositol-1,3-diphosphate (sodium salt)

Cat.No: T37060

2-Methylthioadenosine diphosphate trisodium

Cat.No: T23581

Synonym: 2 Methylthio ADP,2MeSADP,2-Methylthio-ADP,2 MeS ADP,2-MeS-ADP

5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)

Cat.No: T36973

Yimitasvir diphosphate

Cat.No: T74588

Combretastatin A1 phosphate

Cat.No: T72182

Synonym: Oxi4503,CA1P,Oxi4503 ; CA1P ; Combretastatin A1 diphosphate,Combretastatin A1 diphosphate

Adenosine 3',5'-diphosphate sodium salt

Cat.No: T35572

Synonym: 3'-Phosphoadenosine 5'-phosphate

Target: Endogenous Metabolite

Farnesyl Pyrophosphate ammonium

Cat.No: T78081

Synonym: Farnesyl diphosphate ammonium

Geranyl diphosphate

Cat.No: T73807

Aristeromycin diphosphate

Cat.No: T69264

Oxythiamine diphosphate ammonium

Cat.No: T64282

Cidofovir diphosphate tri(triethylamine)

Cat.No: T73983

Uridine 5'-diphosphate

Cat.No: T78583

Target: P2Y Receptor

Thymidine 5′-diphosphate

Cat.No: T73980

Cat.No: T12008

Synonym: Adenosine 5'-(α,β-methylene)diphosphate

Target: Others

Cat.No: T29296

Synonym: Deazafad,5-Deazariboflavin-5'-diphosphate,1-deazaFAD

Uridine diphosphate glucuronic acid ammonium

Cat.No: T73899

Thymidine 3',5'-diphosphate tetrasodium

Cat.No: T73824

Cat. No.	Product Name	Target	Signaling Pathways
T1723	Adenosine 5'-diphosphate 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite	Metabolism
	Adenosine 5'-diphosphate (ADP) 是一种嘌呤核糖核苷5'-二磷酸，是 ATP 在 ATP 酶作用下去磷酸化的产物。Adenosine 5'-diphosphate (adenosine pyrophosphate) 可诱导人血小板聚集并通过作用于P2T-嘌呤受体抑制受刺激的腺苷酸环化酶。
T4706	Uridine-5'-diphosphate disodium salt UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐	DNA/RNA Synthesis; Endogenous Metabolite; P2Y Receptor	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Uridine-5'-diphosphate disodium salt (UDP disodium salt) 是一种选择性 P2Y6受体激动剂，EC50为300 nM，对人 P2Y6受体的 pEC50为6.52。它可刺激炎症介质的产生、吞噬作用和血管收缩，催化多种底物的葡糖醛酸糖化反应，用于核酸生物合成。
T5079	Adenosine 5'-diphosphate sodium salt 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others; Endogenous Metabolite	Metabolism; Others
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) 是一种核苷二磷酸，是一种 ATP 酶对 ATP 去磷酸化的产物。它通过在 P2T-嘌呤受体上的作用诱导人血小板聚集并抑制刺激的腺苷酸环化酶。
T7210	Guanosine 5'-diphosphate GDP,鸟苷-5ˊ-二磷酸	Endogenous Metabolite	Metabolism
	Guanosine 5'-diphosphate (GDP) 是核苷二磷酸，是潜在的铁动员剂，能够阻断铁调素-铁转运蛋白相互作用并调节白细胞介素-6 (IL-6)/stat-3 途径。
T4972	2'-Deoxycytidine-5'-diphosphate trisodium dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。
T40426	Cytidine 5'-diphosphate trisodium salt CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐	Others	Others
	Cytidine 5'-diphosphate trisodium salt (CDP) 可通过尿苷单磷酸激酶 (UMPK) 催化将磷酸基从 ATP 转移到胞苷一磷酸 (CMP) 生成用于合成 DNA 和 RNA 的胞苷三磷酸。
T3228	Fosfructose D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan	Others; Endogenous Metabolite	Metabolism; Others
	D-fructose-1,6-diphosphate 是一种细胞保护性的天然糖磷酸盐，Fosfructose 通过刺激无氧糖酵解起作用，其在缺血条件下产生三磷酸腺苷,有潜力用于心血管缺血，镰状细胞性贫血和哮喘的研究。
T0136	Citicoline CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline	Apoptosis; Dopamine Receptor; Endogenous Metabolite	Apoptosis; GPCR/G Protein; Metabolism; Neuroscience
	Citicoline (CDP-Choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体，有神经保护作用。
T83789	7-Deazaadenosine-5'-O-diphosphate sodium 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP
	7-Deazaadenosine-5'-O-diphosphate是一种修饰过的核苷酸和tubercidin的代谢物。该化合物通过磷酸化tubercidin形成，并进一步磷酸化生成活性代谢物7-deazaadenosine-5'-O-triphosphate。
T19599	Uridine diphosphate glucose	Others	Others
	Uridine diphosphate glucose is an important intermediate in several different metabolic pathways and biosynthetic reactions.
T0194	Chloroquine phosphate Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate	SARS-CoV; TLR; HIV Protease; Antibiotic; Parasite; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Chloroquine phosphate (Aralen phosphate) 是广泛用于疟疾和类风湿性关节炎的抗疟疾和抗炎剂。它是autophagy 和toll-like receptors 抑制剂，有效抑制SARS-CoV-2(COVID-19) 感染 (EC50=1.13 μM)。
T39025	Adenosine 2',5'-diphosphate sodium
	Adenosine 2',5'-diphosphate sodium is a competitive P2Y1 antagonist with non-selective antagonism at recombinant and human platelet P2X1 receptors.
T8074	Esafosfan trisodium Fosfructose trisodium,D-果糖-1,6-二磷酸三钠盐,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium	Others; Endogenous Metabolite	Metabolism; Others
	Esafosfan trisodium (FDP trisodium) 是一种细胞保护性的天然糖磷酸盐，用于镰状细胞性贫血，心血管缺血和哮喘的研究。Fosfructose trisodium 通过刺激无氧糖酵解起作用，其在缺血条件下产生三磷酸腺苷。
T13264	Uridine 5'-diphosphate sodium salt	Others	Others
	Uridine 5'-diphosphate sodium salt is a selective native agonist of the P2Y6 receptor (EC50: 300 nM; pEC50: 6.52), and also is a potent antagonist of P2Y14 (pEC50: 7.28).
T40454	DMAPP Dimethylallyl diphosphate
	DMAPP, also known as Dimethylallyl pyrophosphate, is an isoprenoid precursor found in all life forms. It serves as an isomer of isopentenyl pyrophosphate (IPP).
T80989	Thymidine-5'-diphosphate-L-rhamnose
	Thymidine-5'-diphosphate-L-rhamnose 可从金褐藻 (Occhromonas malhamensis) 提取。
T6535	Histamine Phosphate 组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Histamine Phosphate (Histamine acid phosphate) 是组胺受体的强激活剂和血管扩张神经剂，可激活一氧化氮合成酶。
T1208	Citicoline sodium Citicoline sodium salt,CDP-choline,胞磷胆碱钠	Apoptosis; Others; Endogenous Metabolite	Apoptosis; Metabolism; Others
	Citicoline sodium (CDP-choline) 是一种合成细胞膜组分磷脂酰胆碱的中间体，有神经保护作用。
T5288	Cytidine-5'-triphosphate disodium 胞苷 5'-三磷酸二钠盐,CTP,Cytidine 5'-triphosphate (disodium salt)	Others; Endogenous Metabolite	Metabolism; Others
	Cytidine-5'-triphosphate disodium (CTP) 是内源性代谢产物的一种。
T1609	NAD+ 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD	NADPH; Endogenous Metabolite	Metabolism
	NAD+ (β-Nicotinamide Adenine Dinucleotide) 即烟酰胺腺嘌呤二核苷酸，是转递氢离子的辅酶。
T4713	Phosphorylcholine chloride calcium salt tetrahydrate Phosphocholine chloride calcium salt tet,胆碱磷酸氯化钙四水,CalciuM Phosphorylcholine Tetrahydrate	Others; Endogenous Metabolite	Metabolism; Others
	Phosphorylcholine chloride calcium salt tetrahydrate (Phosphocholine chloride calcium salt tet) 是内源性代谢产物的一种。
TJO2758	D-Glucuronic acid D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) 是一种从许多树胶中分离出的重要中间体。它对皮肤具有抗炎作用。它及其衍生物葡萄糖醛酸内酯作为预防人类健康的肝脏解毒剂。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine (Deoxyribose cytidine) 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
TN1309	6-Hydroxykaempferol-3,6,7-triglucoside	Others	Others
	6-Hydroxykaempferol 3,6,7-tri-O-glucoside and 6-hydroxykaempferol 3,6-di-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.
TN5661	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
	1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood.
TN2725	2',5,6',7-Tetrahydroxyflavanone	Others	Others
	(2S)-2',5,6',7-Tetrahydroxyflavanone can inhibit the lipid peroxide formation induced by adenosine diphosphate and reduced nicotinamide adenine dinucleotide phosphate in rat liver homogenate.
TN1310	6-Hydroxykaempferol 3,6-diglucoside	Others	Others
	6-Hydroxykaempferol 3,6-di-O-glucoside and 6-hydroxykaempferol 3,6,7-tri-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation.
TN4664	Norarmepavine	Others	Others
	N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)- N-norarmepavine exhibits significa

天然产物

Adenosine 5'-diphosphate

Cat.No: T1723

Synonym: 腺苷5'-二磷酸,Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Uridine-5'-diphosphate disodium salt

Cat.No: T4706

Synonym: UDP disodium salt,Uridine 5'-diphosphate disodium salt hyd,尿苷-5'-二磷酸二钠盐

Target: DNA/RNA Synthesis, Endogenous Metabolite, P2Y Receptor

Adenosine 5'-diphosphate sodium salt

Cat.No: T5079

Synonym: 腺苷-5‘-二磷酸钠盐,Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

Guanosine 5'-diphosphate

Cat.No: T7210

Synonym: GDP,鸟苷-5ˊ-二磷酸

Target: Endogenous Metabolite

2'-Deoxycytidine-5'-diphosphate trisodium

Cat.No: T4972

Synonym: dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐

Target: Endogenous Metabolite

Cytidine 5'-diphosphate trisodium salt

Cat.No: T40426

Synonym: CDP,胞苷5'-二磷酸三钠盐水合物,胞苷-5-二磷酸三钠盐,胞苷-5'-二磷酸三钠盐

Target: Others

Cat.No: T3228

Synonym: D-fructose-1,6-diphosphate,Betulanonaprenol,4937-84-2,Diphosphofructose,二磷酸果糖,Fructose 1,6-diphosphate,D-fructofuranose 1,6-bisphosphate,Esafosfan

Target: Others, Endogenous Metabolite

Cat.No: T0136

Synonym: CDP-Choline,Citicholine,尼古林,cytidine 5'-diphosphocholine,cytidine diphosphate-choline

Target: Apoptosis, Dopamine Receptor, Endogenous Metabolite

7-Deazaadenosine-5'-O-diphosphate sodium

Cat.No: T83789

Synonym: 7-CH-ADP,Tubercidin 5’-diphosphate,TuDP

Uridine diphosphate glucose

Cat.No: T19599

Target: Others

Chloroquine phosphate

Cat.No: T0194

Synonym: Chloroquine diphosphate,Aralen phosphate,磷酸氯喹,Chingamin phosphate

Target: SARS-CoV, TLR, HIV Protease, Antibiotic, Parasite, Autophagy

Adenosine 2',5'-diphosphate sodium

Cat.No: T39025

Esafosfan trisodium

Cat.No: T8074

Synonym: Fosfructose trisodium,D-果糖-1,6-二磷酸三钠盐,D-Fructose-1,6-diphosphate trisodium salt octahydrate,FDP trisodium,Diphosphofructose trisodium

Target: Others, Endogenous Metabolite

Uridine 5'-diphosphate sodium salt

Cat.No: T13264

Target: Others

Cat.No: T40454

Synonym: Dimethylallyl diphosphate

Thymidine-5'-diphosphate-L-rhamnose

Cat.No: T80989

Histamine Phosphate

Cat.No: T6535

Synonym: 组胺磷酸盐,Histamine diphosphate,二磷酸组胺,Histamine acid phosphate

Target: Histamine Receptor

Citicoline sodium

Cat.No: T1208

Synonym: Citicoline sodium salt,CDP-choline,胞磷胆碱钠

Target: Apoptosis, Others, Endogenous Metabolite

Cytidine-5'-triphosphate disodium

Cat.No: T5288

Synonym: 胞苷 5'-三磷酸二钠盐,CTP,Cytidine 5'-triphosphate (disodium salt)

Target: Others, Endogenous Metabolite

Cat.No: T1609

Synonym: 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

Target: NADPH, Endogenous Metabolite

Phosphorylcholine chloride calcium salt tetrahydrate

Cat.No: T4713

Synonym: Phosphocholine chloride calcium salt tet,胆碱磷酸氯化钙四水,CalciuM Phosphorylcholine Tetrahydrate

Target: Others, Endogenous Metabolite

D-Glucuronic acid

Cat.No: TJO2758

Synonym: D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid

Target: Others, Endogenous Metabolite

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

6-Hydroxykaempferol-3,6,7-triglucoside

Cat.No: TN1309

Target: Others

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one

Cat.No: TN5661

2',5,6',7-Tetrahydroxyflavanone

Cat.No: TN2725

Target: Others

6-Hydroxykaempferol 3,6-diglucoside

Cat.No: TN1310

Target: Others

Cat.No: TN4664

Target: Others

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