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56

抑制剂 & 化合物

9

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T14965	Ciliobrevin D	ATPase; Hedgehog/Smoothened	GPCR/G Protein; Membrane transporter/Ion channel; Stem Cells
	Ciliobrevin D 是细胞渗透性，可逆和特异性的 AAA + ATPase 运动细胞质动力蛋白抑制剂。它在体外抑制依赖于动力蛋白的微管滑动和 ATPase 活性。它抑制Hedgehog 信号和初级纤毛形成。
TP1563	Gap19	Gap Junction Protein	Cytoskeletal Signaling
	Gap19 是一种衍生自 Cx43 细胞质环九个氨基酸的肽，是选择性连接蛋白 43 半通道阻滞剂。它可以防止 C 末端与 CL 的分子内相互作用，具有保护心肌作用。
T4074	GSK-872 GSK872,GSK'872,GSK2399872A	RIP kinase	Apoptosis; NF-κB
	GSK-872 (GSK2399872A) 是一种有效且特异性的 RIP3 激酶抑制剂，降低 RIPK3 介导的坏死和随后的 HMGB1 的细胞质易位和表达，可改善早期脑损伤中的脑水肿和神经功能缺损。它以高亲和力结合 RIP3 激酶结构域，IC50为1.8 nM，并抑制激酶活性，IC50为1.3 nM。
T77349	CCR1/5/8 activator 1	Phospholipase	Metabolism
	CCR1/5/8 activator 1 是胞质磷脂酶 A 抑制剂，具有抗真菌活性。
T13881	Dicirenone SC26304	ATPase; Glucocorticoid Receptor	Endocrinology/Hormones; Membrane transporter/Ion channel
	Dicirenone (SC26304) 对盐皮质激素受体（MR）有抑制作用，对醛固酮对尿 K+:Na+ 比例的调节和醛固酮与肾细胞质和核受体结合有抑制作用。
T20913	Light Green SF Yellowish Acid Green 5,C.I. Acid Green 5,C.I. 42095
	Light Green SF Yellowish (Acid Green 5) 是一种碱性染色剂，可用于动物组织染色，可用于植物组织学中作细胞质和纤维染色。
T2274	SC79 SC 79,2-氨基-6-氯-alpha-氰基-3-(乙氧羰基)-4H-1-苯并吡喃-4-乙酸乙酯	Akt	Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	SC79 是一个 AKT 激动剂，具有特异性和血脑屏障渗透性。SC79 可以特异性结合 AKT 的 PH 结构域，激活胞质中 AKT，并抑制 AKT 膜转位。SC79 具有神经保护活性。
T25214	CCR-11 CCR11,CCR 11	Antibiotic	Microbiology/Virology
	CCR-11 是一种具有抗菌活性的绕丹宁衍生物。 CCR-11 可以抑制 B. subtilis细胞和 HeLa 细胞增殖。 CCR-11 通过抑制 FtsZ 的组装和 GTPase 活性来抑制细菌增殖和细菌胞质分裂。 CCR-11 具有潜在的抗肿瘤活性，可用于研究乳腺癌和小儿骨髓增生异常。
T0187	Amorolfine hydrochloride Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002	Antibiotic; Antifungal	Microbiology/Virology
	Amorolfine hydrochloride (Amorolfine HCl) 是一种抗真菌剂。
T38722	(Z)-PUGNAc	Others	Others
	(Z)-PUGNAc是一种强效的O-GlcNAcase抑制剂，它比(E)-PUGNAc更有活性，能清除蛋白质上的O-GlcNAc（肽O-GlcNAc-β-N-乙酰氨基葡萄糖苷酶），并可用于增加体内核蛋白和细胞质蛋白上的O-GlcNAc水平。
T15183	Dynarrestin	Hedgehog/Smoothened	GPCR/G Protein; Stem Cells
	Dynarrestin 是一种细胞质动力蛋白 1 和 2的氨基噻唑抑制剂。它能够快速的、可逆的抑制动力蛋白 1 驱动的微管在体外滑动和细胞内动力蛋白 1 和 2 依赖性过程，且不影响 ATP 水解和干扰纤毛发生。它可抑制神经元前体和肿瘤细胞的刺猬因子依赖性增殖。
T61428	4-PQBH	Others	Others
	4-PQBH 是一种有效的 Nur77 结合剂，具有抗肿瘤活性。4-PQBH通过 Nur77 介导的内质应激和自噬广泛诱导半胱天冬酶非依赖性细胞质空泡化和旁睑下垂，抑制异种移植肿瘤。4-PQBH 可用于研究肝癌。
T1561	Clobetasol propionate Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,丙酸氯倍他索,CCl 4725	Glucocorticoid Receptor; P450	Endocrinology/Hormones; Metabolism
	Clobetasol propionate (CGP9555) 是CYP3A5的选择性抑制剂(IC50:0.206 μM)，而对 CYP3A4 或其他主要 CYP 无抑制作用。它是皮质类固醇，对于牛皮癣和其他皮肤病具有潜在的研究价值。
T6529	Halobetasol propionate 卤贝他索丙酸酯,Halobetasol Propionate,Ulobetasol propionate,BMY-30056,卤倍他索丙酸酯,CGP-14458	Phospholipase	Metabolism
	Halobetasol propionate (BMY-30056) 是一种在皮肤外使用的合成类固醇，具有抗炎，止痒和收缩血管的活性。
TP1565L1	Foxy-5 Ammonium Salt Foxy-5 Ammonium Salt（881188-51-8 Free base)	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	Foxy-5 Ammonium Salt是 WNT5A 激动剂，是 WNT5A 的一个模拟肽，是 Wnt 家族的非经典成员。Foxy-5 Ammonium Salt可在不影响 β-catenin 激活的情况下触发胞浆游离钙信号传导，并可抑制上皮癌细胞的迁移和侵袭。Foxy-5 Ammonium Salt在原位小鼠模型中能有效降低 WNT5A 低表达的前列腺癌细胞的转移扩散。
T1666	Fludrocortisone acetate 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate	Glucocorticoid Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Fludrocortisone acetate (9α-Fludrocortisone acetate) 是一种合成的盐皮质激素，可减少尿液中钠丢失量，也用于增加血压，有用于阿狄森氏病的研究潜力。
T3626	Acalabrutinib ACP-196,阿可替尼	BTK	Angiogenesis; Tyrosine Kinase/Adaptors
	Acalabrutinib (ACP-196) 是一种不可逆的、高效的、具有口服活性、选择性的第二代BTK 抑制剂。它与 BTK 的 ATP 结合口袋中的 Cys481 共价结合。它在慢性淋巴细胞性白血病 (CLL) 小鼠模型中显示出强大的靶向作用和功效。
T37739	N-decanoyl-L-Homoserine lactone C10-HSL,N-decanoyl-L-Homoserine lactone	Reactive Oxygen Species; Antibacterial	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	N-decanoyl-L-Homoserine lactone (C10-HSL) 是一种由克雷莫里色假单胞菌菌株 ND07产生的 N-acyl-homoserine lactone (AHL)。N-decanoyl-L-homoserine lactone 可抑制拟南芥的主根生长。N-decanoyl-L-homoserine lactone 处理可引起拟南芥根胞质游离 Ca2+ 和活性氧 (ROS) 浓度短暂和和立即升高，增加丝裂原激活蛋白激酶 6 (MPK6) 的活性，并促使一氧化氮 (NO) 的产生。
T30507	BMS-229724 LS-46643,42AD6D8ECA,BMS229724,SCHEMBL3304414,BMS 229724
	BMS-229724 is a tightly bound inhibitor of cytoplasmic phospholipase A2 with anti-inflammatory activity.
TP2278	NTR 368	Others	Others
	cytoplasmic peptide of the neurotrophin receptor p75NTR
T30745	Carboxy-pyridostatin
	Carboxy-pyridostatin, as a fluorescent probe, can target G-quadruplex structures and trap cytoplasmic RNA G-quadruplex structures in cells.
T38773	LeuRS-IN-1 hydrochloride
	LeuRS-IN-1 hydrochloride is a potent and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS). It has IC 50 and Kd values of 0.06 μM and 0.075 μM, respectively, for M.tb LeuRS. Additionally, LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS with an IC 50 of 38.8 μM and HepG2 protein synthesis with an EC 50 of 19.6 μM.
T75747	Indolicidin acetate
	Indolicidin acetate 是一种从牛中性粒细胞的细胞质颗粒中纯化的强效抗菌肽。
T28891	SW106
	SW106 is a selective antagonist of PTHR1-mediated cAMP signaling, not functioning as an inverse agonist on either PTHR1-T410P or PTHR1-H223R, which have activating mutations at the cytoplasmic ends of TMD helices-2 and -6, respectively.
TP1511	Gap19 TFA (1507930-57-5 free base) Gap19 TFA
	Gap19 TFA is a peptide derived from nine amino acids of Cx43 cytoplasmic ring (CL), an effective, selective connexin 43 (Cx43) half-channel blocker.
T38775	LeuRS-IN-1
	LeuRS-IN-1 is a highly potent and orally active inhibitor of the leucyl-tRNA synthetase enzyme derived from Mycobacterium tuberculosis (M.tb LeuRS). It exhibits significant inhibitory activity against M.tb LeuRS with IC 50 and Kd values of 0.06 μM and 0.075 μM, respectively. Additionally, LeuRS-IN-1 effectively inhibits human cytoplasmic LeuRS with an IC 50 value of 38.8 μM and suppresses protein synthesis in HepG2 cells with an EC 50 value of 19.6 μM.
T64237	ASB14780
	ASB14780 是一种 4-苯氧衍生物，是一种胞质磷脂酶 cPLA2α 抑制剂 (IC50: 20 nM)。
TP1498	FFAGLDD TFA
	FFAGLDD TFA is an MMP9 selective cleavage peptide, which is used for the cytoplasmic transfer of doxorubicin (DOX) to realize the controlled slow drug delivery and release.
TP2149	NP213 TFA (942577-31-3 free base) NP213 TFA	Others	Others
	NP213 TFA is a rapidly acting and first-in-class synthetic antimicrobial peptide (AMP) with anti-fungal activity. It targets the fungal cytoplasmic membrane via membrane perturbation and disruption.
T75748	Indolicidin TFA
	Indolicidin TFA 是一种从牛中性粒细胞的细胞质颗粒中纯化的强效抗菌肽。
TP2149L	NP213	Epigenetic Reader Domain	Chromatin/Epigenetic
	NP213 is a rapidly acting synthetic antimicrobial peptide (AMP). NP213 is effective and well-tolerated in resolving nail fungal infections. NP213 has anti-fungal activities. NP213 targets the fungal cytoplasmic membrane and plays its role via membrane perturbation and disruption.
T82176	HR1
	HR1是一种乳突蛋白酶，可增加人红细胞膜渗透性，并能诱导细菌细胞质膜和肥大细胞质膜透化。
T63631	hCAII-IN-2
	hCAII-IN-2 是胞质型人碳酸酐酶 (hCA) 抑制剂，能够作用于 hCA I (Ki: 261.4 nM)、hCA II (Ki: 3.8 nM)、hCA IX (Ki: 19.6 nM)和 hCA XII (Ki: 45.2 nM)。
T76456	Protein Kinase C (19-35) Peptide
	Protein Kinase C (19-35) Peptide 是PKC 假底物抑制剂/区域。Protein Kinase C (19-35) Peptide 阻断PKC 激酶结构域的底物结合位点，使PKC 的细胞质形式失活。
T78752	Antibacterial agent 145
	Antibacterialagent 145 (compound 1b)为依赖于细菌铁摄取途径的抗菌剂，能破坏细胞质膜完整性并抑制细菌细胞代谢，同时对正常细胞具有低细胞毒性。
T79668	PIK5-12d	Autophagy	Autophagy
	PIK5-12d为一种高效的PROTAC PIKfyve降解剂，具有显著的DC50值为1.48 nM。该化合物在多种前列腺癌细胞系中有效诱导细胞质空泡化，同时阻碍自噬流的进行，有效抑制前列腺癌细胞的增殖，并展现出抗肿瘤活性。
TP1910	CALP1
	Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibit
T81837	MCaE12A
	MCaE12A作为RyR2的高亲和调节剂，提高了RyR2对细胞质Ca2+浓度的敏感性，并促使通道开启。该化合物是在RyR2从结构到功能研究中的关键工具，同时用于控制心肌细胞Ca2+的稳态和动态。
T61721	RAGE 229
	RAGE 229, N-(4-(7-cyano-4-(morpholin-4ylmethyl) quinolin-2-yl)phenyl)acetamide 是一种小分子 ctRAGE-DIAPH1抑制剂，具有口服活性。RAGE 229 可通过抑制 ctRAGE 与 DIAPH1 的相互作用来抑制细胞内 RAGE 信号。
T69873	Cefdinir monohydrate
	Cefdinir monohydrate is the salt form of Cefdinir (free base), a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidog...
T73916	NP213 TFA
	NP213 TFA是一种具有抗真菌(anti-fungal)活性的快速、新颖的合成抗菌肽(AMP)。该化合物通过瞄准真菌胞质膜并扰乱及破坏其结构来发挥作用，对甲真菌感染显示出高效与良好耐受性。
T8812	Amorolfine HCL	Antibiotic	Microbiology/Virology
	Amorolfine HCL 是一种抗真菌试剂。它通过选择性地中断麦角甾醇合成途径中的两个步骤并随后破坏真菌细胞膜的功能和结构来发挥抗真菌活性。阿莫罗芬是一种吗啉类抗真菌药物，可抑制 D14 还原酶和 D7-D8 异构酶。这些酶可以消耗麦角甾醇并导致木甾醇在真菌细胞质细胞膜中积累。
T82086	ICMT-IN-7
	ICMT-IN-7（化合物74）是一种高效的ICMT抑制剂，其IC50值为0.015 μM。该化合物能剂量依赖性地在HCT-116细胞中诱导ICMT蛋白在胞质的积累，并能抑制表达K-Ras和N-Ras的多种癌细胞系的增殖。
T36871	5-Octyl-α-ketoglutarate
	In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-α-ketoglutarate, also known as α-ketoglutarate octyl ester, is a stable, cell-permeable molecule that generates free α-ketoglutarate upon hydrolysis of the ester bond by cytoplasmic esterases. It is used in experiments to increase levels of intracellular α-ketoglutarate. 5-Octyl-α-ketoglutarate has been shown to modulate a variety of enzymes and signaling pathway...
T80261	Retro-indolicidin
	Retro-indolicidin为一具有生物活性的肽，由13个氨基酸残基组成，依据indolicidin序列设计而成。Indolicidin属于cathelicidin蛋白家族，为从牛中性粒细胞细胞质颗粒分离得到的阳离子抗菌肽酰胺。该合成肽（Rev4）已证实显示出显著的体外抗菌和蛋白酶抑制活性。
T80106	Z-Pro-Pro-aldehyde-dimethyl acetal	Prolyl Endopeptidase (PREP)	Metabolism; Proteases/Proteasome
	Z-Pro-Pro-aldehyde-dimethyl acetal 是一种高效的脯氨酸内肽酶(PRE P)抑制剂，其IC50值为12 nM。该化合物在衰老过程和神经退行性疾病，诸如阿尔茨海默病中认知功能障碍的研究中具有重要作用。
T82136	ICMT-IN-1
	ICMT-IN-1 (化合物75) 作为一种高效的ICMT抑制剂展现出显著活性（IC50=0.0013 μM），能够剂量依赖性地在HCT-116细胞中导致ICMT的胞质内积累，进而有效抑制携带K-Ras和N-Ras变异的多个癌细胞系的增殖。
T75820	Gap19 TFA
	Gap19 TFA，源自Cx43胞浆环(CL)的九个氨基酸肽，是高效且选择性的连接蛋白43 (Cx43) 半通道阻滞剂。该肽阻止C末端（CT）与CL之间的分子内相互作用，但不影响GJ通道或Cx40/pannexin-1半通道。此外，Gap19 TFA对心肌有保护作用。
T79703	RyRs activator 3	Parasite	Microbiology/Virology
	RyRs activator 3 (compound A4) 作为有效杀虫剂，针对斑小菜蛾 (M. separata) 及小菜蛾 (P. xylostella) 显示出较高效力，其对斑小菜蛾的 LC50 值达到 3.27 mg/L。通过与兰尼碱受体 (ryanodine receptor) 结合，RyRs activator 3 能增加细胞质中 Ca2+ 的浓度，从而产生生物毒性。
T32091	Hofman's Violet
	Hoffman's violet is specific stains for animal chromosomes. Iodinated alcohol after staining can be substituted with various acids, both organic as well as inorganic, all of which act as trapping agent preventing leaching of the dye that binds with the ch

化合物

Cat.No: T14965

Target: ATPase, Hedgehog/Smoothened

Cat.No: TP1563

Target: Gap Junction Protein

Cat.No: T4074

Synonym: GSK872,GSK'872,GSK2399872A

Target: RIP kinase

CCR1/5/8 activator 1

Cat.No: T77349

Target: Phospholipase

Cat.No: T13881

Synonym: SC26304

Target: ATPase, Glucocorticoid Receptor

Light Green SF Yellowish

Cat.No: T20913

Synonym: Acid Green 5,C.I. Acid Green 5,C.I. 42095

Cat.No: T2274

Synonym: SC 79,2-氨基-6-氯-alpha-氰基-3-(乙氧羰基)-4H-1-苯并吡喃-4-乙酸乙酯

Target: Akt

Cat.No: T25214

Synonym: CCR11,CCR 11

Target: Antibiotic

Amorolfine hydrochloride

Cat.No: T0187

Synonym: Amorolfin,盐酸阿莫洛芬,Amorolfine HCl,盐酸阿莫罗芬,Ro 14-4767/002

Target: Antibiotic, Antifungal

Cat.No: T38722

Target: Others

Cat.No: T15183

Target: Hedgehog/Smoothened

Cat.No: T61428

Target: Others

Clobetasol propionate

Cat.No: T1561

Synonym: Dermovate,Clobetasol 17-propionate,CGP9555,Temovate,丙酸氯倍他索,CCl 4725

Target: Glucocorticoid Receptor, P450

Halobetasol propionate

Cat.No: T6529

Synonym: 卤贝他索丙酸酯,Halobetasol Propionate,Ulobetasol propionate,BMY-30056,卤倍他索丙酸酯,CGP-14458

Target: Phospholipase

Foxy-5 Ammonium Salt

Cat.No: TP1565L1

Synonym: Foxy-5 Ammonium Salt（881188-51-8 Free base)

Target: Wnt/beta-catenin

Fludrocortisone acetate

Cat.No: T1666

Synonym: 9α-Fluorcortisol acetate,9α-Fludrocortisone acetate,醋酸氟氢可的松,9α-fluorocortisol acetate

Target: Glucocorticoid Receptor, Autophagy

Cat.No: T3626

Synonym: ACP-196,阿可替尼

Target: BTK

N-decanoyl-L-Homoserine lactone

Cat.No: T37739

Synonym: C10-HSL,N-decanoyl-L-Homoserine lactone

Target: Reactive Oxygen Species, Antibacterial

Cat.No: T30507

Synonym: LS-46643,42AD6D8ECA,BMS229724,SCHEMBL3304414,BMS 229724

Cat.No: TP2278

Target: Others

Carboxy-pyridostatin

Cat.No: T30745

LeuRS-IN-1 hydrochloride

Cat.No: T38773

Indolicidin acetate

Cat.No: T75747

Cat.No: T28891

Gap19 TFA (1507930-57-5 free base)

Cat.No: TP1511

Synonym: Gap19 TFA

Cat.No: T38775

Cat.No: T64237

Cat.No: TP1498

NP213 TFA (942577-31-3 free base)

Cat.No: TP2149

Synonym: NP213 TFA

Target: Others

Indolicidin TFA

Cat.No: T75748

Cat.No: TP2149L

Target: Epigenetic Reader Domain

Cat.No: T82176

Cat.No: T63631

Protein Kinase C (19-35) Peptide

Cat.No: T76456

Antibacterial agent 145

Cat.No: T78752

Cat.No: T79668

Target: Autophagy

Cat.No: TP1910

Cat.No: T81837

Cat.No: T61721

Cefdinir monohydrate

Cat.No: T69873

Cat.No: T73916

Cat.No: T8812

Target: Antibiotic

Cat.No: T82086

5-Octyl-α-ketoglutarate

Cat.No: T36871

Retro-indolicidin

Cat.No: T80261

Z-Pro-Pro-aldehyde-dimethyl acetal

Cat.No: T80106

Target: Prolyl Endopeptidase (PREP)

Cat.No: T82136

Cat.No: T75820

RyRs activator 3

Cat.No: T79703

Target: Parasite

Hofman's Violet

Cat.No: T32091

Cat. No.	Product Name	Target	Signaling Pathways
T10065L	2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium	STING; cGAS	Immunology/Inflammation
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) 是一种cGAMP 合成酶(cGAS)影响细胞质DNA 产生的第二信使，是一种跨膜衔接蛋白，是细胞对致病性细胞质DNA 的先天免疫反应的关键组成部分。
T1429	17α-Hydroxyprogesterone Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮	Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism; Others
	17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素，其他类固醇激素（包括糖皮质激素，雌激素，和雄激素）生物合成的化学中间体。
TQ0302	Thapsigargin 毒胡萝卜素	Apoptosis; SARS-CoV; Calcium Channel	Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Thapsigargin 属于天然产物，是一种肌/内质网 Ca2+ ATP 酶 (SERCA) 的抑制剂，也是一种内质网应激诱导剂。Thapsigargin 通过阻断细胞将钙泵入肌浆和内质网的能力来提高胞浆钙浓度。
T40600	Iturin A
	Iturin A is a chemical compound with potent antifungal properties against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell, leading to the formation of ion conducting pores.
T19343	sn-Glycerol 3-phosphate Glycerol 3-phosphate,SN-甘油3-磷酸锂盐,sn-Glycerol 3-phosphate lithium salt	Endogenous Metabolite	Metabolism
	sn-Glycerol 3-phosphate 是一种人内源性化合物，由NADH 还原磷酸二羟基丙酮而产生。
T37972	12-OxoETE
	12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via a leukotriene B4 receptor or a common activation sequence.
T80998	Thapsigargicin Thapsigargicine
	Thapsigargicin（Thapsigargicine）作为肥大细胞和白细胞的激活剂，能诱导大鼠腹膜肥大细胞及人嗜碱性粒细胞释放组胺，并提升完整人血小板中的细胞质游离钙水平。
T13606L	cGAMP disodium
	cGAMP disodium 是在细菌中发现的一种环二核苷酸 (CDN) ，可作为内源性第二信使，影响干扰素的产生以响应胞浆 DNA。cGAMP disodium 通过激活干扰素基因刺激因子 (STING)使 I 型干扰素和其他免疫介质的信号产生级联现象。cGAMP disodium 是一种有效的舌下免疫佐剂，能使免疫功能（血清抗 PA 中和和气道分泌物抗 PA SIgA 反应）更好的发挥作用。
T35751	Violacein
	Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserine lactone , a property that has been modified to create a strain of C. violaceum used in detecting quorum-sensing molecules.[3] Violacein is active against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.8 and 1.6 &#181M, respectively). It is also active aga...

天然产物

2',3'-cGAMP sodium

Cat.No: T10065L

Synonym: 2'-3'-cyclic GMP-AMP sodium

Target: STING, cGAS

17α-Hydroxyprogesterone

Cat.No: T1429

Synonym: Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮

Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite

Cat.No: TQ0302

Synonym: 毒胡萝卜素

Target: Apoptosis, SARS-CoV, Calcium Channel

Cat.No: T40600

sn-Glycerol 3-phosphate

Cat.No: T19343

Synonym: Glycerol 3-phosphate,SN-甘油3-磷酸锂盐,sn-Glycerol 3-phosphate lithium salt

Target: Endogenous Metabolite

Cat.No: T37972

Cat.No: T80998

Synonym: Thapsigargicine

Cat.No: T13606L

Cat.No: T35751

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