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48

抑制剂 & 化合物

5

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Cat. No. Product Name Target Signaling Pathways
T4007 Eticlopride hydrochloride

Dopamine Receptor GPCR/G Protein; Neuroscience
Eticlopride hydrochloride 是一种抗精神病药,是一种选择性多巴胺 D2/D3 受体拮抗剂(Ki:0.5/0.16 nM)。
T10603 BRD-6929

HIV Protease; HDAC Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
BRD-6929 是一种选择性的脑渗透性的HDAC1和HDAC2抑制剂 ,IC50值为 1 和 8 nM。它对 HDAC1 和 HDAC2 有高亲和力,Ki 值为  0.2 和 1.5 nM。它可研究情绪相关行为。
T21635 PD184161

MEK MAPK
PD 184161 是一种口服有效的,时间和浓度依赖的 MEK 抑制剂,IC50为10-100 nM。它诱导抑郁样行为,抑制细胞增殖并诱导细胞凋亡。
T26091 Riparin III

Riparin III is an alcamide isolated from Aniba riparia that has exhibited effects of antidepressant and anxiolytic activities in acute stress behavioral models.
T27186 Divaplon

RU-32698,RU32698,RU 32698

GABA Receptor Membrane transporter/Ion channel; Neuroscience
Divaplon 是一种GABA 受体激动剂(IC50:0.056 µM),在大鼠模型中显示出非镇静性抗焦虑行为特征,可用于治疗焦虑症。
TP1578L Neuropeptide EI, rat acetate

Neuropeptide EI, rat acetate(125934-45-4 free base)

Melanocortin Receptor; Melanin-concentrating Hormone Receptor (MCHR) GPCR/G Protein; Neuroscience
Neuropeptide EI, rat acetate(125934-45-4 free base) 在不同的行为范例中显示功能性 MCH 拮抗剂和 MSH 激动剂活性。
T68080 Gevotroline

5-HT Receptor GPCR/G Protein; Neuroscience
Gevotroline 是棕榈酒中的一种可用来治疗精神病的化学物,是5-HT2 receptor 拮抗剂,可用于研究行为障碍。
T79909 AEF0117

Cannabinoid Receptor GPCR/G Protein
AEF0117为一种针对大麻素受体1 (CB1-SSi) 的信号传导特异性抑制剂,抑制大麻素自我给药和与四氢大麻酚相关的行为障碍,可用于研究大麻戒断。
T10142L p-Ethynylphenylalanine hydrochloride

4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)

Hydroxylase Metabolism
p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) 是一种高效的、可逆的、选择性的、竞争性的色氨酸羟化酶 (TPH) 抑制剂,其Ki=32.6 μM。
T33816 Ordopidine

ACR-325,ACR 325,ACR325

Dopamine Receptor GPCR/G Protein; Neuroscience
Ordopidine (ACR325) 是一种多巴胺能稳定剂,可抑制精神刺激剂引起的多动症,并在不活动时刺激行为。Ordopidine 在体外作为多巴胺 D2 受体拮抗剂起作用,尽管亲和力低,但其依赖于特定状态的行为效应特征是 D2 受体拮抗剂所不具备的。
T27806 Lecozotan HCl

SRA-333,SRA333,SRA 333,Lecozotan hydrochloride

5-HT Receptor GPCR/G Protein; Neuroscience
Lecozotan HCl (SRA-333) 是一种强效且具有选择性的 5-HT 拮抗剂。Lecozotan HCl能明显增强氯化钾刺激海马齿状回谷氨酸和乙酰胆碱的释放并具有增强认知能力的特性。在表明 5-HT(1A) 受体功能的行为模型中,长期服用Lecozotan HCl不会诱发 5-HT(1A) 受体耐受或脱敏。
T68070 Fezolamine

Norepinephrine Neuroscience
Fezolamine 是一种新型可口服的非三环类化合物,具有抗抑郁活性。它在体外阻断[3H]去甲肾上腺素的突触体摄取方面的选择性是摄取[4H]3-羟色胺或[3H]多巴胺的3至2倍。在使用单胺耗尽动物的经典行为测试中,它阻止了利血平和四苯的抑制作用。
T22043 BCATc Inhibitor 2

Others Others
BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂,可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM),hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1,存在于细胞质基质中的亚型。
T28634 RY024

RY024 is a behavioral alcohol antagonist.
T33696 NK-1145

NK-1145 hydrocholdoride,NK 1145,NK1145

Nk-1145 is a parasympathetic drug of the autonomic nervous system, which can cause behavioral stimulation and excitement.
T33607 NBI-34041

NBI34041,SB 723620,SB-723620,SB723620

NBI-34041 is an effective and high-affinity CRF1 receptor antagonist that effectively reduces endocrine responses to CRF(1) receptor-mediated pharmacological and behavioral challenges.
T27857 LSP4-2022

LSP42022,LSP4 2022

LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.
T24857 TBTC

TBTC is a selective agonist of retinoid X receptor α that acts by improving behavioral deficit in Alzheimer's disease model mice.
T20821 EPPS

EPPS is a rescuer of A aggregation and behavioral deficits. It binds to A aggregates and converts them into monomers.
TP1578 Neuropeptide EI, rat

Displays functional MCH-antagonist and MSH-agonist activity in different behavioral paradigms.
T29206 ZCZ011

ZCZ 011,ZCZ-011

ZCZ011 is a positive allosteric modulator of the cannabinoid CB1 receptor. ZCZ011 is brain penetrant, increased the potency of orthosteric agonists in mouse behavioral assays indicative of cannabimimetic activity, including antinociception, hypothermia, c
TP1504 Urocortin III, mouse TFA (357952-10-4 free base)

Urocortin III, mouse TFA

Urocortin III, mouse TFA is a corticotropin-releasing factor (CRF)-related peptide. Urocortin III preferentially binds and activates CRF-R2. Urocortin III (Ucn3) is a known component of the behavioral stress response system. Urocortin III and CRF-R2 in th
T28316 PD 118717

PD118717,PD-118717

PD 118717 is a putative piperazinyl benzopyranone dopamine autoreceptor agonist. PD 118717 has the profile of a DA autoreceptor agonist and produces effects suggestive of antipsychotic efficacy without neurological side effect liability in preclinical beh
TP2052 CTOP

Potent and selective μ opioid receptor antagonist (Ki values are 0.96 and >10,000 nM for μ and δ receptors respectively). Causes behavioral effects on central administration in vivo. Also increases K+ currents in rat locus ceruleus neurons in vitro via a
TP1732 Galanin (1-30), human

Galanin (1-30), human is a 30-amino acid neuropeptide, and acts as an agonist of GalR1 and GalR2 receptors, with Kis of both 1 nM. Endogenous peptide with multiple endocrine, metabolic and behavioral effects. Has been shown to have an action on intestinal
T38005 P11149

P11149 is a competitive, BBB-penetarated weakly, orally active and selective inhibitor of AChE. P11149 exhibits an IC50 of 1.3 μM for rat BChE/AChE. P11149, a Galanthamine derivative, demonstrates central cholinergic activity, behavioral efficacy and safety. P11149 is used in the study for Alzheimer’s disease[1]. P11149 is a GAL analog that is rapidly hydrolyzed in vivo to yield the potent AChE inhibitor, 6-DMG[1].P11149 exhibits greater s.c. bioavailability than p.o. [1].Oral P11149 in mice pr...
T60577 Cycrimine

Cycrimine 是毒蕈碱胆碱能受体(mAChR)M1的口服活性拮抗剂,可降低帕金森模型中乙酰胆碱的水平。Cycrimine 具有解痉活性,可用于研究行为和精神障碍。
T79172 PF-06655075

Oxytocin Receptor Endocrinology/Hormones; GPCR/G Protein
PF-06655075为一新型非脑渗透性OT受体(oxytocin receptor)激动剂,具有显著提高对OT受体(oxytocin receptor)的选择性和药代动力学稳定性。PF-06655075可用作工具化合物,以研究外周OT在行为反应中的功能。
T70643 GT-0198 HCl

GT-0198 is a novel glycine transporter 2 inhibitor showed activity in a mouse model of neuropathic pain. GT-0198 inhibited the function of glycine transporter 2 (GlyT2) in human GlyT2-expressing HEK293 cells and did not bind various major transporters or receptors of neurotransmitters in a competitive manner. GT-0198 is considered to be a comparatively selective GlyT2 inhibitor. GT-0198 is a structurally novel GlyT2 inhibitor bearing a phenoxymethylbenzamide moiety with in vivo efficacy in beha...
T81501 PF-06655075 TFA

Oxytocin Receptor Endocrinology/Hormones; GPCR/G Protein
PF-06655075(TFA)为PF-06655075的三氟乙酸(TFA)形态。该化合物是一种创新的非脑渗透性氧催产素(oxytocin receptor)受体激动剂,且对氧催产素受体具有较高的选择性,药代动力学稳定性得到显著增强。PF-06655075可用作工具化合物,以深入研究外围氧催产素受体在行为反应中的功能。
T76025 Urocortin III, mouse TFA

Urocortin III, mouse TFA是CRF(促肾上腺皮质激素释放因子)相关的肽。该化合物主要通过结合并激活CRF-R2发挥作用。Urocortin III(Ucn3)是已知参与调节行为压力反应体系的组分之一。它和CRF-R2在大脑杏仁核中共同作用,从而参与调控复杂的社会动力学行为。
T80134 Pro8-Oxytocin TFA

Oxytocin Receptor Endocrinology/Hormones; GPCR/G Protein
Pro8-Oxytocin TFA 作为一种优化的OXT配体,在灵长类动物OXTR上展现出较Leu8-Oxytocin更强的功能反应和行为效应。相对于AVP,在人类AVPR1a上的活性较低,但在狨猴AVPR1a上则显示出更高的活性。
T80133 Pro8-Oxytocin

Oxytocin Receptor Endocrinology/Hormones; GPCR/G Protein
Pro8-Oxytocin是一种改良的OXT配体。在灵长类动物OXTR中,Pro8-Oxytocin比标准哺乳动物OXT配体Leu8-Oxytocin诱发更强效的反应和显著的行为影响。相较于Vasopressin (AVP),Pro8-Oxytocin对人类AVPR1a的活性较低,但对狨猴AVPR1a的激活作用则高于AVP。
T63549 MRGPRX1 agonist 4

MRGPRX1 agonist 4 是有效的、口服具有活力的 Mas 相关 G 蛋白偶联受体 X1 (MRGPRX1)正向变构调节剂 (EC50: 0.1 μM)。MRGPRX1 agonist 4 表现出良好的代谢稳定性以及口服生物利用度。MRGPRX1 agonist 4 能够改善人源性 MRGPRX1 神经疼痛模型小鼠行为性热过敏反应。
T76230 p-fin4

p-fin4,作为一种针对STEP Phosphatase-GluA2 AMPA受体相互作用的肽抑制剂,具有0.4 μM的Ki值。在东莨菪碱处理的大鼠模型中,p-fin4能够恢复记忆功能,并展现出抗焦虑及抗抑郁效果。该化合物是开发新型认知增强剂和/或行为调节剂的有希望的先导物。
T71327 Paraxanthine-d6

Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agoni...
T76229 p3Ysh-3

p3Ysh-3 是 STEP Phosphatase-GluA2 AMPA 受体相互作用的肽抑制剂,Ki 为 1.09 μM。p3Ysh-3 在东莨菪碱处理的大鼠模型中恢复记忆缺陷并表现出抗焦虑和抗抑郁作用。p3Ysh-3 是一种很有前途的先导化合物,可用于新型认知增强剂和/或行为调节剂。
T75832 Cyclotraxin B TFA

Cyclotraxin B TFA 是一种环肽,是一种高效且选择性的 TrkB 抑制剂,且不会改变 BDNF 的结合。Cyclotraxin B TFA 非竞争性地抑制 BDNF 诱导的 TrkB 活性,IC50值为 0.30 nM。Cyclotraxin B TFA 可以穿越血脑屏障,并具有止痛和抗焦虑的行为作用。
T62303 PDE4B/7A-IN-1

化合物22是一种1安/5-羟丁腈橡胶7受体拮抗剂(5-HT1a ki=8 nm, kb=0.04 nm;5-nitrile rubber 7K i=451 nm, kb=460 nm),同时具备PDE4B/PDE7A抑制活性(PDE4B IC50= 80.4 μM;PDE7A IC50= 151.3 μM)。该化合物在体外展现出了优秀的生物膜被动穿透能力和高代谢稳定性。进一步的药理学评估揭示,22在大鼠行为测试中展现了显著的认知改善和抗抑郁效果。
T36482 Lamotrigine isethionate

Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents. Leach et al (1991) Neurochemical and behavioral aspects of lamotr. Epilepsia 32 S4 PMID:1685439 |Smith and Meldrum (1995) Cardioprotective effect of lamotr. after focal ischemia in rats. Stroke 26 117 PMID:7839380 |Zona and Avoli (1997) Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture. Epilepsia 38 522 PMI...
T76014 IGF-I (24-41) (TFA)

IGF-I (24-41) TFA(Insulin-like Growth Factor I (24-41) TFA)是类胰岛素生长因子I的一个氨基酸片段,覆盖24至41位点。作为一种70个氨基酸组成的多肽激素,IGF-I TFA对神经元和神经胶质细胞具有营养作用,而且在调节全身生长激素(GH)活性中扮演关键角色。它还具备合成代谢、抗氧化、抗炎及细胞保护功能,对躯体生长及行为发育调节作用显著。
T38228 R 121919 hydrochloride

High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM). Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable. Chen and Grigoriadis (2005) NBI 30775 (R121919), an orally active antagonist of the corticotropin-releasing factor (CRF) type-1 receptor for the treatment of anxiety and depression. Drug Dev.Res. 65 216 |Jutkiewicz et al (2005) The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919...
T65396 Piperazine 2HCl

Piperazine (2HCl) is gamma-aminobutyric acid (GABA) agonists and its major effects appear to be on the central nervous system. Piperazine was the anthelmintic with the greatest number of reports of toxicoses and suspected toxicoses in cats. Piperazine neurotoxicity in cats and dogs usually was manifested by muscle tremors, ataxia, and/or behavioral disturbances within 24 hours after estimated daily dose(s) between 20 and 110 mg/kg[1]. For di-substituted derivatives, ciprofloxacin was selected an...
T37837 2-Methylhexacosane

2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone.1,2It has been found in the cuticle ofM. dasystomusfemales, but not males, where it contributes to the mating behavior of males, as well as inD. melanogasterfemales where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.3 1.Spikes, A.E., Pashen, M.A., Millar, J.G., et al.First contact pheromone identified for a longhorned beetle (Coleoptera: ...
T35814 Urocortin III (human) (trifluoroacetate salt)

Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively)....
T35836 PMX-205 (trifluoroacetate salt)

PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR; IC50= 31 nM).1It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma.2,3PMX-205 is also brain penetrant and reduces neuroinflammation and neurodegeneration in an animal model of Alzheimer's disease.4 1.March, D.R., Proctor, L.M., Stoermer, M.J., et al.Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Rela...
T35892 Q134R

Q134R

Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer’s disease (AD) and aging-related disorders research[1]. Q134R (1-10 μM) suppresses NFAT signaling, without inhibiting calcineurin activity. Q134R partially inhibits NFAT activity in primary rat astrocytes, but does not prevent calcineurin-mediated dephosphorylation of a non-NFAT target, either in vivo...
T35560 SAR502250

SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD)[1][2]. SAR502250 (0.01-1 μM; 36 h) attenuates the Aβ25-35-induced cell death in rat embryonic hippocampal neurons[2]. SAR502250 (1-100 mg/kg; a single p.o,) attenuates tau hyperphosphorylation in the cortex and spinal cord of transgenic mic...

化合物

Eticlopride hydrochloride
Cat.No: T4007
Synonym:
Target: Dopamine Receptor
BRD-6929
Cat.No: T10603
Synonym:
Target: HIV Protease, HDAC
PD184161
Cat.No: T21635
Synonym:
Target: MEK
Riparin III
Cat.No: T26091
Synonym:
Target:
Divaplon
Cat.No: T27186
Synonym: RU-32698,RU32698,RU 32698
Target: GABA Receptor
Neuropeptide EI, rat acetate
Cat.No: TP1578L
Synonym: Neuropeptide EI, rat acetate(125934-45-4 free base)
Target: Melanocortin Receptor, Melanin-concentrating Hormone Receptor (MCHR)
Gevotroline
Cat.No: T68080
Synonym:
Target: 5-HT Receptor
AEF0117
Cat.No: T79909
Synonym:
Target: Cannabinoid Receptor
p-Ethynylphenylalanine hydrochloride
Cat.No: T10142L
Synonym: 4-Ethynyl-L-phenylalanine HCL,p-Ethynylphenylalanine hydrochloride(278605-15-5 free base)
Target: Hydroxylase
Ordopidine
Cat.No: T33816
Synonym: ACR-325,ACR 325,ACR325
Target: Dopamine Receptor
Lecozotan HCl
Cat.No: T27806
Synonym: SRA-333,SRA333,SRA 333,Lecozotan hydrochloride
Target: 5-HT Receptor
Fezolamine
Cat.No: T68070
Synonym:
Target: Norepinephrine
BCATc Inhibitor 2
Cat.No: T22043
Synonym:
Target: Others
RY024
Cat.No: T28634
Synonym:
Target:
NK-1145
Cat.No: T33696
Synonym: NK-1145 hydrocholdoride,NK 1145,NK1145
Target:
NBI-34041
Cat.No: T33607
Synonym: NBI34041,SB 723620,SB-723620,SB723620
Target:
LSP4-2022
Cat.No: T27857
Synonym: LSP42022,LSP4 2022
Target:
TBTC
Cat.No: T24857
Synonym:
Target:
EPPS
Cat.No: T20821
Synonym:
Target:
Neuropeptide EI, rat
Cat.No: TP1578
Synonym:
Target:
ZCZ011
Cat.No: T29206
Synonym: ZCZ 011,ZCZ-011
Target:
Urocortin III, mouse TFA (357952-10-4 free base)
Cat.No: TP1504
Synonym: Urocortin III, mouse TFA
Target:
PD 118717
Cat.No: T28316
Synonym: PD118717,PD-118717
Target:
CTOP
Cat.No: TP2052
Synonym:
Target:
Galanin (1-30), human
Cat.No: TP1732
Synonym:
Target:
P11149
Cat.No: T38005
Synonym:
Target:
Cycrimine
Cat.No: T60577
Synonym:
Target:
PF-06655075
Cat.No: T79172
Synonym:
Target: Oxytocin Receptor
GT-0198 HCl
Cat.No: T70643
Synonym:
Target:
PF-06655075 TFA
Cat.No: T81501
Synonym:
Target: Oxytocin Receptor
Urocortin III, mouse TFA
Cat.No: T76025
Synonym:
Target:
Pro8-Oxytocin TFA
Cat.No: T80134
Synonym:
Target: Oxytocin Receptor
Pro8-Oxytocin
Cat.No: T80133
Synonym:
Target: Oxytocin Receptor
MRGPRX1 agonist 4
Cat.No: T63549
Synonym:
Target:
p-fin4
Cat.No: T76230
Synonym:
Target:
Paraxanthine-d6
Cat.No: T71327
Synonym:
Target:
p3Ysh-3
Cat.No: T76229
Synonym:
Target:
Cyclotraxin B TFA
Cat.No: T75832
Synonym:
Target:
PDE4B/7A-IN-1
Cat.No: T62303
Synonym:
Target:
Lamotrigine isethionate
Cat.No: T36482
Synonym:
Target:
IGF-I (24-41) (TFA)
Cat.No: T76014
Synonym:
Target:
R 121919 hydrochloride
Cat.No: T38228
Synonym:
Target:
Piperazine 2HCl
Cat.No: T65396
Synonym:
Target:
2-Methylhexacosane
Cat.No: T37837
Synonym:
Target:
Urocortin III (human) (trifluoroacetate salt)
Cat.No: T35814
Synonym:
Target:
PMX-205 (trifluoroacetate salt)
Cat.No: T35836
Synonym:
Target:
Q134R
Cat.No: T35892
Synonym: Q134R
Target:
SAR502250
Cat.No: T35560
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0632 3,4,5-Trimethoxybenzoic acid

Gallic acid trimethyl ether,Eudesmic acid,3,4,5-三甲氧基苯甲酸,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid,没食子酸三甲醚

Antioxidant oxidation-reduction
3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) 是一种苯甲酸衍生物,可用作医药和有机合成中的砌块。
T4S1999 Valepotriate

戊曲酯/缬草素,Valtrate

Apoptosis; HIV Protease Apoptosis; Microbiology/Virology; Proteases/Proteasome
Valepotriate (Valtrate) 是从蜘蛛香分离而来的一种天然产物,是一类新的细胞毒剂和抗肿瘤剂,对 HTC 肝癌细胞是非常有效的细胞毒剂。 它可能对焦虑的精神症状具有潜在的抗焦虑作用。
T5S0661 Koumine

Others Others
Koumine 是一种从钩吻中得到的生物碱,具有高效抗肿瘤活性,在肿瘤细胞中能够提高 Bax/Bcl-2 的蛋白比例和 caspase-3 的表达。在类风湿性关节炎动物模型中,它能够预防关节炎的发展。它具有抗焦虑、抗应激、抗银屑病作用,也可用于缓解疼痛的研究。
T4S0969 Obtusifolin

决明蒽醌,决明蒽醌;美决明子素

Antioxidant; NF-κB NF-κB; oxidation-reduction
Obtusifolin 是分离自决明子的种子中,能够抑制NF-kB 通路,调节气道上皮细胞中 MUC5AC 粘蛋白的基因表达和产生。它通过靶向甲状旁腺激素相关蛋白来抑制邻苯二甲酸酯诱导的乳腺癌骨转移。
TN1766 (-)-Integerrimine

Integerrimine,全緣千里光鹼,全缘千里光碱

Others Others
Prenatal exposure to Integerrimine N-oxide induces maternal toxicity, impairment of maternal care and delayed in physical and behavioral development of the offspring. Doses of Integerrimine N-oxide here employed did not produce marked immunotoxic effects.

天然产物

3,4,5-Trimethoxybenzoic acid
Cat.No: T0632
Synonym: Gallic acid trimethyl ether,Eudesmic acid,3,4,5-三甲氧基苯甲酸,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid,没食子酸三甲醚
Target: Antioxidant
Valepotriate
Cat.No: T4S1999
Synonym: 戊曲酯/缬草素,Valtrate
Target: Apoptosis, HIV Protease
Koumine
Cat.No: T5S0661
Synonym:
Target: Others
Obtusifolin
Cat.No: T4S0969
Synonym: 决明蒽醌,决明蒽醌;美决明子素
Target: Antioxidant, NF-κB
(-)-Integerrimine
Cat.No: TN1766
Synonym: Integerrimine,全緣千里光鹼,全缘千里光碱
Target: Others
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