107
14
2
90
Cat. No. | Product Name | ||
---|---|---|---|
L7600 | 趋化因子抑制剂库 | 59 compounds | |
59 种趋化因子或其受体抑制剂的独特集合,可用于高通量筛选和高内涵筛选; | |||
L1100 | 蛋白酶抑制剂库 | 343 compounds | |
343 种已知的小分子蛋白酶抑制剂的特有集合,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3686 |
10074-G5
|
c-Myc; Autophagy | Autophagy; Cell Cycle/Checkpoint |
10074-G5是一种c-Myc-Max 二聚化的抑制剂,IC50值为146 μM。 | |||
T6313 |
Go 6983
Goe 6983 |
PKC | Chromatin/Epigenetic; Cytoskeletal Signaling |
Go 6983 是一种PKC 抑制剂,能够作用于PKCα、PKCβ、PKCγ、PKCδ和PKCζ,IC50值分别为 7、7、6、10 和 60 nM。 | |||
T40286 |
KRAS G12C inhibitor 19
|
Ras | GPCR/G Protein; MAPK |
KRAS G12C inhibitor 19 是一种有效的 KRAS G12C 抑制剂,在细胞实验中显示出抗肿瘤活性,科抑制肿瘤生长。 | |||
T11346L |
G3-C12 acetate(848301-94-0 free base)
|
Galectin | Immunology/Inflammation |
G3-C12 acetate(848301-94-0 free base) 显示出抗癌活性。是一种半乳糖凝集素 3 结合肽,Kd 为 88 nM。 | |||
T11738 |
K-Ras G12C-IN-4
|
Ras | GPCR/G Protein; MAPK |
K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。 | |||
T6556 |
K-Ras(G12C) inhibitor 9
|
Raf | MAPK |
K-Ras(G12C) inhibitor 9 是致癌 K-Ras(G12C) 的变构抑制剂。 | |||
T6555 |
K-Ras(G12C) inhibitor 12
|
Apoptosis; Raf; Ras | Apoptosis; GPCR/G Protein; MAPK |
K-Ras(G12C) inhibitor 12是一种K-Ras(G12C)抑制剂,作用于H1792细胞,EC50为0.32 μM。 | |||
T3725 |
K-Ras(G12C) Inhibitor 6
|
Raf | MAPK |
KRas(G12C) inhibitor 6 是一种变构的,选择性的 K-Ras(G12C)抑制剂。 | |||
T9317 |
TAK-041
NBI-1065846 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
TAK-041 (NBI-1065846) 是一种选择性 GPR139激动剂,EC50为 22 nM,有用于精神分裂症阴性症状的研究潜力。 | |||
T20043 |
D&C Red no. 31
D &,C Red no. 31,11067 Red,Brilliant Scarlet G,CCRIS 4906,Pigment Scarlet Toner RB |
||
D & C Red no. 31 is an agent of dye. | |||
T35520 |
Aflatoxin G1-13C17
Aflatoxin G1-13C17 |
||
Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase... | |||
T40285 |
KRAS G12C inhibitor 18
|
||
KRAS G12C inhibitor 18 is a potent, orally active compound that inhibits KRAS G12C and exhibits anti-tumor activities. | |||
T80256 |
C18G
|
||
C18G为源自人血小板因子IV的合成α-螺旋肽,具备生物活性。研究表明,C18G显示出抗菌效果,尤其对沙门氏菌有活性。 | |||
T35521 |
Aflatoxin G2-13C17
Aflatoxin G2-13C17 |
||
Aflatoxin G2-13C17is intended for use as an internal standard for the quantification of aflatoxin G2by GC- or LC-MS. Aflatoxin G2is a mycotoxin that has been found inAspergillus.1It is lethal to ducklings (LD50= 2.83 mg/kg) but is non-toxic to rats when administered at a dose of 200 mg/kg.2 1.Bennett, J.W., and Klich, M.MycotoxinsClin. Microbiol. Rev.16(3)497-516(2003) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins a... | |||
T75027 | G0-C14 | ||
G0-C14,一种阳离子类脂烷基修饰的聚氨基胺(PAMAM)树状大分子,适用于巨噬细胞靶向纳米颗粒(NPs)系列的制备,并可用于活性分子与疫苗递送。 | |||
T75986 |
G3-C12 TFA
|
||
G3-C12 (TFA) 是 galectin-3 结合肽,Kd 值为 88 nM,具有抗肿瘤活性。 | |||
T79555 |
G43-C3-TEG
|
||
G43-C3-TEG为糖基转移酶抑制剂,其作用机制在于降低EPS(细胞外多糖)的生成,进而减少生物膜形成。 | |||
T63501 | KRAS G12C inhibitor 30 | ||
KRAS G12C inhibitor 30 是 KRAS G12C 的抑制剂,能够用于研究癌症。 | |||
T79808 |
KRAS G12C inhibitor 61
|
ERK | MAPK |
KRAS G12C inhibitor 61 (Example 3) 在 MIA PaCa-2 细胞中抑制 ERK1/2 磷酸化,其 IC50 为 9 nM。此化合物适用于胰腺癌、结直肠癌和肺癌的研究。 | |||
T64142 |
KRAS G12C inhibitor 46
|
||
KRAS G12C inhibitor 46 是一种 KRAS G12C 的有效抑制剂。 | |||
T72356 |
KRAS G12C inhibitor 56
|
||
KRAS G12C inhibitor 56(化合物IC-6),作为一种SOS1抑制剂,显示出1.6 nM的IC50值,表明其对于癌症研究的潜在应用价值。 | |||
T72334 |
KRAS G12C inhibitor 28
|
||
KRAS G12C inhibitor 27 是一种KRAS G12C 抑制剂,其IC50为 57 nM,具有抗肿瘤作用。 | |||
T63807 |
KRAS G12C inhibitor 33
|
||
KRAS G12C inhibitor 33 是 KRAS G12C 抑制剂,能够用于研究癌症。 | |||
T72336 | KRAS G12C inhibitor 45 | ||
KRAS G12C inhibitor 45 是一种有效的KRAS G12C 抑制剂。 | |||
T63502 | KRAS G12C inhibitor 31 | ||
KRAS G12C inhibitor 31 是 KRAS G12C 的抑制剂,能够用于研究癌症。 | |||
T72343 | KRAS G12C inhibitor 40 | ||
KRAS G12C inhibitor 40 是一种有效的KRAS G12C 抑制剂。Ras 蛋白家族是一种重要的细胞内信号分子,在生长发育中起重要作用。KRAS G12C inhibitor 40 具有研究 KRAS G12C 介导的癌症的潜力。 | |||
T72347 | KRAS G12C inhibitor 24 | ||
KRAS G12C inhibitor 24 是一种有效KRAS G12C 抑制剂。KRAS G12C inhibitor 24 抑制 KRAS G12C/SOS1 相互作用,IC50小于 50 nM。 | |||
T79166 |
KRAS G12C inhibitor 60
|
Ras | GPCR/G Protein; MAPK |
KRAS G12C inhibitor 60 (compound 23)作为一种高效的Kras-G12C抑制剂, 主要应用于肺癌、结直肠癌和胰腺癌的研究领域。 | |||
T62785 |
KRAS G12C inhibitor 29
|
||
KRAS G12C inhibitor 29 是一种 KRAS G12C 的抑制剂,能够用于研究癌症。 | |||
T62566 |
KRAS G12C inhibitor 53
|
||
KRAS G12C inhibitor 53 (Compound 1) 是一种 KRAS G12C 抑制剂。 | |||
T63927 | KRAS G12C inhibitor 25 | ||
KRAS G12C inhibitor 25 是 KRAS G12C 抑制剂。KRAS G12C inhibitor 25 能够抑制 KRAS-G12C 突变体的 SOS1 辅助的 GDP/GTP 交换活性,其 IC50 值为 0.48 nM。 | |||
T79057 |
KRAS G12C inhibitor 58
|
Ras | GPCR/G Protein; MAPK |
KRAS G12C inhibitor 58作为KRAS G12C的抑制剂,专门用于癌症领域的研究应用。 | |||
T79150 |
KRAS G12C inhibitor 59
|
Ras | GPCR/G Protein; MAPK |
KRAS G12C inhibitor 59,作为KRAS G12C的特异性抑制剂,展现出了抗肿瘤活性。 | |||
T64115 |
KRAS G12C inhibitor 51
|
||
KRAS G12C inhibitor 51 是一种 KRAS G12C 抑制剂。 | |||
T64095 |
KRAS G12C inhibitor 42
|
||
KRAS G12C inhibitor 42 是 KRAS G12C 的有效抑制剂。其中 Ras 蛋白家族是一种重要的细胞内信号分子,在生长发育中发挥着重要作用。KRAS G12C inhibitor 42 对 KRAS G12C 介导的癌症表现出研究潜力。 | |||
T63863 |
KRAS G12C inhibitor 47
|
||
KRAS G12C inhibitor 47 是 KRAS G12C 的有效抑制剂 (IC50: 0.172 μM)。KRAS G12C inhibitor 47 在 MIA PaCA-2 细胞、A549 细胞中表现出 p-ERK 抑制作用,他们的 IC50 值分别为 0.046 μM、69.8 μM。KRAS G12C inhibitor 47 对胰腺癌,结直肠癌和肺癌表现出研究潜力。 | |||
T72335 |
KRAS G12C inhibitor 32
|
Ras | GPCR/G Protein; MAPK |
KRAS G12C inhibitor 32,一种含有八个原子的N杂环化合物,作为KRAS G12C的有效抑制剂。 | |||
T64033 |
KRAS G12C inhibitor 34
|
||
KRAS G12C inhibitor 34 是一种 KRAS G12C 的抑制剂,能够用于研究癌症研究。 | |||
T72346 |
KRAS G12C inhibitor 20
|
||
KRAS G12C inhibitor 20 是一种KRAS G12C 的抑制剂。 | |||
T72340 |
KRAS G12C inhibitor 37
|
||
KRAS G12C inhibitor 37 是一种有效的 KRAS G12C 抑制剂。Ras 蛋白家族是一种重要的细胞内信号分子,在生长发育中起重要作用。KRAS G12C inhibitor 37 具有研究 KRAS G12C 介导的癌症的潜力。 | |||
T64085 |
KRAS G12C inhibitor 43
|
||
KRAS G12C inhibitor 43 是 KRAS G12C 的有效抑制剂,能够抑制 H358 细胞 (IC50: 0.001-1 μM μM)、 A549 细胞 (IC50>1 μM)、 HCC 细胞 (IC50>1 μM) 的迁移和增殖。 | |||
T63926 |
KRAS G12C inhibitor 22
|
||
KRAS G12C inhibitor 22 是 KRAS G12C 抑制剂。 | |||
T64093 | KRAS G12C inhibitor 44 | ||
KRAS G12C inhibitor 44 是一种有效的、口服具有活力的 KRAS G12C 抑制剂。KRAS G12C inhibitor 44 在 MIA PaCA-2 (IC50: 0.016 μM)、H358 细胞 (IC50: 0.028 μM) 中表现出抗增殖作用。KRAS G12C inhibitor 44 在体内具有抗肿瘤活性。 | |||
T64039 | KRAS G12C inhibitor 49 | ||
KRAS G12C inhibitor 49 是一种口服具有活力的 KRAS G12C 抑制剂,表现出抗肿瘤作用。 | |||
T72338 | KRAS G12C inhibitor 35 | ||
KRAS G12C inhibitor 35 是一种有效的KRAS G12C 抑制剂。Ras 蛋白家族是一种重要的细胞内信号分子,在生长发育中起重要作用。KRAS G12C inhibitor 35 具有研究 KRAS G12C 介导的癌症的潜力。 | |||
T72344 | KRAS G12C inhibitor 41 | ||
KRAS G12C inhibitor 40 是一种有效的 KRAS G12C 抑制剂。Ras 蛋白家族是一种重要的细胞内信号分子,在生长发育中起重要作用。KRAS G12C inhibitor 40 具有研究 KRAS G12C 介导的癌症的潜力。 | |||
T64097 |
KRAS G12C inhibitor 21
|
||
KRAS G12C inhibitor 21 是一种 KRAS G12C 抑制剂。 | |||
T72348 |
KRAS G12C inhibitor 48
|
||
KRAS G12C inhibitor 48 是一种有效的KRAS G12C 抑制剂,IC50为 639.91 nM。 KRAS G12C inhibitor 48 (0-50 µM) 具有抗增殖活性,对 H358,H23,A549 细胞的 IC50s 分别为 0.796,6.33,16.14 µM. | |||
T63891 |
KRAS G12C inhibitor 50
|
||
KRAS G12C inhibitor 50 是 KRAS G12C 抑制剂 (IC50: 46.7 nM)。 | |||
T72342 |
KRAS G12C inhibitor 39
|
||
KRAS G12C inhibitor 39 是一种有效的KRAS G12C 抑制剂。KRas 是制药行业癌症研究的一个极具吸引力的目标。KRAS G12C inhibitor 39 具有研究 KRAS G12C 介导的癌症的潜力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T26030 |
Rabdosin C
Isodonoiol,Rabdophyllin G |
||
Rabdosin C is an antineoplastic isolated from the leaves of Rabdosia japonic. | |||
T82799 |
C-2′-Decoumaroylaloeresin G
|
||
C-2′-Decoumaroylaloeresin G (化合物8)为一种色酮糖苷,源自芦荟属植物。 | |||
TMA1603 |
Parishin C
巴利森苷 C,巴利森苷C |
Antioxidant | oxidation-reduction |
Parishin C 是一种从天麻中分离出的 Parishin 衍生物,可能具有抗氧化作用。 | |||
T3811 |
Ginsenoside C-K
20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K |
P450; cell cycle arrest; COX; NO Synthase | Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience |
Ginsenoside C-K (Ginsenoside K) 是 Ginsenoside Rb1 的细菌代谢物,可通过抑制诱生型一氧化氮合酶和COX-2来发挥抗炎作用。它在人肝微粒体中抑制CYP2C9和CYP2A6活性,IC50分别为 32.0±3.6 和 63.6±4.2 μM。 | |||
T19165 |
8-Hydroxyguanine
8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine |
Endogenous Metabolite | Metabolism |
8-Hydroxyguanine (8 Hydroxyguanine)是由活性氧物质产生的主要诱变前损伤。 它导致G-T和A-C置换。8-Hydroxyguanine 是一种 RNA 氧化和 DNA 氧化损伤的生物标记物。8-Hydroxyguanine 具有致突变性和致癌性,常用于癌症实验中。 | |||
T5S0636 |
Citric acid
柠檬酸,Citro,Citretten |
Apoptosis; Others; Endogenous Metabolite; Antibacterial; Antibiotic | Apoptosis; Metabolism; Microbiology/Virology; Others |
Citric acid (Citro) 是柑橘类水果中发现的弱有机三羧酸。柠檬酸是食品添加剂和天然防腐剂。 | |||
TN6059 |
Demethoxyfumitremorgin C
|
||
Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via the intrinsic (mitochondrial) and ex | |||
T38258 |
Phanerosporic Acid
|
||
Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. niger, O. ulmi, U. maydis, C. cucmerinum, C. cladosporioides, and B. cinerea.1 It has been used in the synthesis of macrolide derivatives.References1. Arnone, A., Assante, G., Nasini, G., et al. Phanerosporic acid, a β-resorcylate obtained from Phanerochaete chrysosporium. Phytoch... | |||
TN5580 | Rediocide A | ||
Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other than methuselah, it can induce GPCR desensitization and internalization, and such effects are mediated by the activation of conventional | |||
T38086 |
Neohydroxyaspergillic Acid
|
||
Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. mycoides, and B. subtilis bacteria (MICs = 125-500 μg/ml). Neohydroxyaspergillic acid also inhibits the growth of G. convolute, S. consortiale, P. blakesleeanus, C. globosum, and T. mentagrophytes (MICs = 175-700 μg/ml) but not A. niger, P. notatum, M. verrucaria, or S. cerevisiae ... | |||
T35409 |
(+)-δ-Cadinene
|
Apoptosis; Antibacterial | Apoptosis; Microbiology/Virology |
(+)-δ-Cadinene 是一种从G. hirsutum 中发现的倍半萜,具有抗菌、杀虫、抗癌和抗增殖活性。 它对肺炎双球菌的MIC 值为31.25 μg/ml,对 A. stephensi、A. aegypti 和 C. quinquefasciatust 三龄幼虫的LC50s 值分别8.23、9. 2和3。(+)-δ-Cadinene(10、50 和 100 μM)可诱导 OVCAR-3 人类卵巢癌细胞凋亡并抑制其增殖。 | |||
T37609 |
(rel)-Asperparaline A
|
||
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) larval neurons (IC50s = 20.2 and 39.6 nM, respectively) but has no effect on chicken α3β4-, α4β2-, and α7-containing nAChRs.2 Dietary administration of aspergillimide A (10 μg/g of diet) induces paralysis in silkworm fourth instar larvae.1 Aspergillimide A (10 and 20 mg/kg) reduces... | |||
T36000 |
3-Hydroxyterphenyllin
|
||
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi... | |||
T38069 |
Aquastatin A
|
||
Aquastatin A is a fungal metabolite originally isolated fromF. aquaeductuumthat has diverse biological activities.1It is active againstS. aureus(MIC = 32 μg/ml) and inhibits enoyl-acyl carrier protein reductase (Fabl; IC50= 3.2 μM) andS. aureusfatty acid synthesis (IC50= 3.5 μM).2Aquastatin A also inhibits the Na+/K+-ATPase and H+/K+-ATPase (IC50s = 7.1 and 6.2 μM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B; IC50= 0.19 μM).1,3 1.Hamano, K., Kinoshita-Okami, M., Minagawa, K.... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00857 |
IL-2RG Protein, Mouse, Recombinant (His & hFc)
gamma(c),interleukin 2 receptor, ... |
Mouse | HEK293 Cells |
IL-2RG Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 56.3 kDa and the accession number is P34902. | |||
TMPJ-00749 |
IgG1 hFc Protein, Human, Recombinant
IGHG1,g gamma-1 c |
Human | HEK293 Cells |
IgG1 hFc Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32 KDa and the accession number is P01857. | |||
TMPJ-00750 |
IgG1 hFc Protein, Human, Recombinant, Biotinylated
g gamma-1 chain C re... |
Human | HEK293 Cells |
IgG1 hFc Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 33 KDa and the accession number is P01857. | |||
TMPJ-00597 |
IgG1 hFc Protein, Mouse, Recombinant
g γ-1 chain C region, |
Mouse | HEK293 Cells |
As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light cha... | |||
TMPY-04116 |
KRAS Protein,Human,Recombinant(G12C & Q61H, His)
NS,CFC2,K-RAS4B,C-K-RAS,KRAS2,K-R... |
Human | E. coli |
KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2. | |||
TMPY-01837 |
IL-2RG Protein, Mouse, Recombinant (His)
gamma(c),interleukin 2 receptor, ... |
Mouse | HEK293 Cells |
IL-2RG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30 kDa and the accession number is P34902. | |||
TMPY-06507 |
IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc)
gc,[g]c,interleukin 2 re... |
Mouse | HEK293 Cells |
IL-2RG Protein, Mouse, Recombinant(aa 1-263, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.68 kDa and the accession number is NP_038591.1. | |||
TMPH-02610 |
CLEC4G Protein, Mouse, Recombinant (His)
C-type lectin domain family 4 member G... |
Mouse | E. coli |
Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner. | |||
TMPY-00646 |
CCL4 Protein, Human, Recombinant (His)
SCYA2,G-26,MIP-1-β,LAG-1,MIP1B,AT... |
Human | P. pastoris (Yeast) |
CCL4 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.2 kDa and the accession number is P13236. | |||
TMPJ-00395 |
SEMA4D Protein, Mouse, Recombinant (hFc)
Semacl2,Sema J,Semaphorin-C-like 2,Semaj,<... |
Mouse | HEK293 Cells |
SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues. However, SEMA4D is expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver. SEMA4D is a cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. S... | |||
TMPY-00551 |
PSG1 Protein, Human, Recombinant (hFc)
PSGIIA,PS-β-C/D,FL-NCA-1/2,PSB |
Human | HEK293 Cells |
PSG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is P11464-1. | |||
TMPY-00552 |
PSG1 Protein, Human, Recombinant (His)
PS-β-G-1,PSBG-1,PS-beta-G-1,C... |
Human | HEK293 Cells |
PSG1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.9 kDa and the accession number is P11464-1. | |||
TMPH-01066 |
CCR6 Protein, Human, Recombinant (His & Myc)
GPRCY4,Chemokine recepto... |
Human | E. coli |
CCR6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 12.9 kDa and the accession number is P51684. | |||
TMPH-02612 |
CXCR3 Protein, Mouse, Recombinant (His & KSI)
CXC-R3,CKR-L2,CXC |
Mouse | E. coli |
Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. | |||
TMPH-01162 |
CXCR3 Protein, Human, Recombinant (GST & His)
IP-10 receptor,CXCR3,CX<... |
Human | E. coli |
CXCR3 Protein, Human, Recombinant (GST & His) is expressed in E. coli. | |||
TMPJ-00510 |
KRAS Protein, Human, Recombinant (G12C, His)
RASK2,c-K-ras,CFC2,KRAS2,Ki-Ras |
Human | E. coli |
KRAS Protein, Human, Recombinant (G12C, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26 KDa and the accession number is AAH13572.1. | |||
TMPH-01134 |
Complement C8g Protein, Human, Recombinant (His)
C8G,Complement component... |
Human | E. coli |
C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Complement C8g Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.4 kDa and the accession number is P07360. | |||
TMPY-00296 |
Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His)
HCV-1a E2 |
HCV | HEK293 Cells |
Hepatitis C virus (HCV) (serotype 1c,isolate HC-G9) E2 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.2 kDa and the accession number is BAA03581.1. | |||
TMPY-06303 |
SARS-CoV-2 Nucleocapsid Protein (P13L & R203K & G204R & G214C, His)
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SARS-CoV-2 | E. coli |
SARS-CoV-2 Nucleocapsid Protein (P13L & R203K & G204R & G214C, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.73 kDa and the accession number is P0DTC9. | |||
TMPY-06304 |
SARS-CoV-2 Nucleocapsid Protein (D63G & R203M & G215C & D377Y, His)
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SARS-CoV-2 | E. coli |
SARS-CoV-2 Nucleocapsid Protein (D63G & R203M & G215C & D377Y, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.60 kDa and the accession number is P0DTC9. | |||
TMPY-04092 |
Histone H4 Protein, Human, Recombinant
HIST1H4E,H4FK,HIST1H4J,H4/M,HIST1H4A,H4FD,H4FC,H4/J... |
Human | E. coli |
Histone H4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.4 kDa and the accession number is B2R4R0. | |||
TMPJ-00040 |
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G)
FGF-2,Fibroblast growth factor 2,... |
Human | E. coli |
FGF-2 Protein, Human,Recombinant (Q65I, C96S, N111G) is expressed in E. coli expression system. The predicted molecular weight is 16 KDa and the accession number is P09038-2. | |||
TMPK-01463 |
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi)
C-K-RAS,KI-RAS,KRAS1,K-RAS4A,KRAS2,CFC... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01433 |
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)
GTPase Kras,NS3,K-Ras 2,K-RAS2B,RALD,MHC,R... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01451 |
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01462 |
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
K-RAS4A,K-RAS2A,CFC2,KRAS1,K-RAS4B,C |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01456 |
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPK-01450 |
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS... |
Human | HEK293 Cells |
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail. | |||
TMPH-03421 |
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) VP7 Protein (His & Myc)
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RV-A | E. coli |
Rotavirus A (strain RVA/Cow/Canada/C486/1977/G6P6[1]) VP7 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.0 kDa and the accession number is A8D8S8. | |||
TMPY-06130 |
SARS-CoV-2 Spike S1 Protein (W152C & L452R & D614G, His)
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SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (W152C & L452R & D614G, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.4 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-06433 |
SARS-CoV-2 Spike S1 Protein (P9L & C136F & 144-145 deletion & R190S & D215G & Y449H & E484K & N501Y & D614G & H655Y & N679K, His)
|
SARS-CoV-2 | HEK293 Cells |
SARS-CoV-2 Spike S1 Protein (P9L & C136F & 144-145 deletion & R190S & D215G & Y449H & E484K & N501Y & D614G & H655Y & N679K, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.06 kDa and the accession number is A0A6G7K2L4. | |||
TMPY-00105 |
Recombinant Protein G
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E. coli | |
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains. It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... | |||
TMPY-01355 |
Transglutaminase 2/TGM2 Protein, Human, Recombinant (His)
G-α-h,HEL-S-45,TGC,transg |
Human | Baculovirus Insect Cells |
Protein-glutamine gamma-glutamyltransferase 2, also known as Tissue transglutaminase, Transglutaminase C, Transglutaminase-2, and TGM2, is a member of the transglutaminase superfamily. TGM2 plays a role in cell growth and survival through the anti-apoptosis signaling pathway. It is a calcium-dependent acyltransferase that also undergoes a GTP-binding/GTPase cycle even though it lacks any obvious sequence similarity with canonical GTP-binding (G) proteins. TGM2 is a multi-functional protein which... | |||
TMPH-01732 |
DDAH1 Protein, Human, Recombinant (His & Myc)
DDAHI,N(G),N(G)-dimethylarginine ... |
Human | E. coli |
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation. DDAH1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.4 kDa and the accession number is O94760. | |||
TMPH-00226 |
ATPase subunit g Protein, Bovine, Recombinant (His & Myc)
ATP synthase subunit g, mitochondrial,ATP5... |
Bovine | E. coli |
ATPase subunit g Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.7 kDa and the accession number is Q28852. | |||
TMPH-00203 |
Bla g 2 Protein, Blattella germanica, Recombinant (His & Myc)
Bla g 2,Aspartic protease Bla g 2... |
Blattella germanica | E. coli |
Functions as a digestive enzyme in the cockroach. Bla g 2 Protein, Blattella germanica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.4 kDa and the accession number is P54958. | |||
TMPH-01386 |
GLP2R Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. GLP2R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 22.0 kDa and the accession number is O95838. | |||
TMPH-01378 |
GIPR Protein, Human, Recombinant (His & Myc)
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Human | HEK293 Cells |
This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. GIPR Protein, Human, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.5 kDa and the accession number is P48546. | |||
TMPH-01065 |
CCR4 Protein-VLP, Human, Recombinant (His)
CC-CKR-4,CCR4,<... |
Human | HEK293 Cells |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cel... | |||
TMPH-02022 |
RXFP2 Protein, Human, Recombinant (His & Myc)
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Human | E. coli |
Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). RXFP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.1 kDa and the accession number is Q8WXD0. | |||
TMPH-03206 |
ITGB8 Protein, Rabbit, Recombinant (His & Myc)
|
Rabbit | E. coli |
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Required during vasculogenesis. ITGB8 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli ... | |||
TMPH-03691 |
VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc)
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VSIV | E. coli |
Attaches the virus to host cellular receptor, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane. VSIV (strain Mudd-Summers) Glycoprotein G Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.8 kDa and the accession number is P0C2X0. | |||
TMPJ-00354 |
FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc)
Frizzled-1,mFz1,Fzd1,Fz-1,Frizzled homolog 1 |
Mouse | HEK293 Cells |
Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. | |||
TMPY-04555 |
GRK5 Protein, Human, Recombinant (His)
G protein-coupled receptor kinase... |
Human | Baculovirus Insect Cells |
G protein-coupled receptor kinase 5, also known as G protein-coupled receptor kinase GRK5 and GRK5, is a member of the protein kinase superfamily, AGC Ser/Thr protein kinase family, and GPRK subfamily. GRKs specifically phosphorylate agonist-occupied G protein-coupled receptors at the inner surface of the plasma membrane (PM), leading to receptor desensitization. GRKs utilize a variety of mechanisms to bind tightly, and sometimes reversibly, to cellular membranes. GRKs play an important role in ... | |||
TMPJ-00895 |
SCF Protein, Rat, Recombinant (HEK293, His)
steel factor,Mast cell growth fa<... |
Rat | HEK293 Cells |
SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I/II... | |||
TMPH-01064 |
CCR4 Protein, Human, Recombinant (His & SUMO)
CMKBR4,CD194,K5-5,CCR-4,... |
Human | E. coli |
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. CCR4 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expressio... | |||
TMPK-01102 |
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (mFc)
ILT4,CD85d,ILT4CD85d,MIR10,LIR2,LILRB2,ILT... |
Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Human, Recombinan... | |||
TMPK-01100 |
LILRB2/CD85d/ILT4 Protein, Human, Recombinant (hFc)
CD85d,ILT-4,LILRB2,ILT4CD85d,ILT4,LIR2,MIR... |
Human | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Human, Recombinan... | |||
TMPK-01313 |
LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (hFc)
ILT-4,MIR10,ILT4,ILT4CD85d,LILRB2,LIR2,CD8... |
Cynomolgus | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recom... | |||
TMPK-01314 |
LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recombinant (His)
CD85d,ILT4CD85d,LIR2,MIR10,LILRB2,ILT4,ILT... |
Cynomolgus | HEK293 Cells |
The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). LILRB2 is a receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C, HLA-G and HLA-F alleles. LILRB2/CD85d/ILT4 Protein, Cynomolgus, Recom... | |||
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