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71

抑制剂 & 化合物

21

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T3042	JAK2 Inhibitor V JAK2 Inhibitor V Z3,Z3	JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	JAK2 Inhibitor V (JAK2 Inhibitor V Z3) 是一种新型的 Jak2 特异性抑制剂，以剂量依赖性方式抑制 Jak2-V617F 和 Jak2-WT 自磷酸化。
T6005	Z-DEVD-FMK Caspase-3 Inhibitor	Caspase	Apoptosis; Proteases/Proteasome
	Z-DEVD-FMK (Caspase-3 Inhibitor) 是一种选择性、不可逆的 Caspase-3 抑制剂，IC50为 18 μM。它也抑制 caspase-6、caspase-7、caspase-8 和 caspase-10。
T10824	cis-Urocanic acid cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸	5-HT Receptor	GPCR/G Protein; Neuroscience
	cis-Urocanic acid ((E)-Urocanic acid) 是一种 5-HT2A 受体激动剂，cis-Urocanic acid 与 5-HT 受体结合的Kd 为 4.6 nM。cis-Urocanic acid 是一种免疫调节剂，通过与 5-HT2A 受体结合而诱导免疫抑制。
T21503	(E/Z)-Zotiraciclib (E/Z)-TG02,(E/Z)-SB1317	FLT; JAK; CDK	Angiogenesis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	(E/Z)-Zotiraciclib ((E/Z)-TG02) 是一种 CDK2、JAK2和FLT3的抑制剂，IC50分别为 13、73 和 56 nM。
T9178	(E/Z)-GSK-3β inhibitor 1 GSK-3β inhibitor 1	GSK-3	PI3K/Akt/mTOR signaling; Stem Cells
	(E/Z)-GSK-3β inhibitor 1 是 (E)-GSK-3β inhibitor 1 和 (Z)-GSK-3β inhibitor 1 的消旋体。它是一种糖原合成酶激酶 3β (GSK-3β)的抑制剂，可其对 GSK-3β 的 IC50=4.9 nM，用于糖尿病的研究。
T39869	(Z)-2-Bromo-3-methyl-2-butenedioic acid cis-2-Bromo-3-methylbutenendioic acid,(Z)-2-溴-3-甲基-2-丁二酸
	(Z)-2-Bromo-3-methyl-2-butenedioic acid is a brominated haloacid that acts as a disinfection byproduct (DBP) in finished drinking waters.
T37336	N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone
	Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener...
T5135	Flupentixol dihydrochloride 盐酸氟哌噻吨,Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Flupentixol dihydrochloride 是噻克西酮类试剂，能够用于研究精神分裂症以及抗焦虑和抑郁障碍。
T35291	Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene
	Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene 是 Methyl eugenol (ME) 的氟类似物，是东方果蝇 B. dorsalis 的引诱剂。E 型异构体的活性是Z型异构体 Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene 的两倍。
T12302	OMDM-1 (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide	Endogenous Metabolite	Metabolism
	OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) 是有效选择性的代谢稳定 anandamide 细胞摄取抑制剂，Ki=为2.4 μM。
T2340	AC1NS4RE	Tyrosinase	Proteases/Proteasome
	是一种化学合成中的砌块
T12628	(R)-MG-132 (S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al	Proteasome	Proteases/Proteasome; Ubiquitination
	(R)-MG-132 (Z-Leu-D-leu-leu-al) 是一种 MG-132 的对映异构体，是一种蛋白酶体 (proteasome) 抑制剂，细胞毒性比 MG-132 弱，是一种比 MG-132 更有效的proteasome 抑制剂。
T60059	methyl (Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate
	methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate 是一种有用的化合物，可用于合成多种有机化合物。
T30626	Butirosamine Z-1159-3
	Butirosamine is a biochemical.
T81609	omega-3 Arachidonic acid ethyl ester (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester
	omega-3 Arachidonic Acid ethyl ester 是一种少见的多不饱和脂肪酸，饮食来源稀少。ω-3脂肪酸对婴幼儿生长发育极为重要，能够帮助预防心脏病、血栓、高血压及炎症和自身免疫性疾病。该化合物在人血小板膜中通过抑制花生四烯酰辅酶A合成酶发挥作用，Ki值达到14 μM；同时在小牛脑提取物中也表现出抑制作用，IC50大约5 μM。omega-3 Arachidonic Acid ethyl ester 作为游离酸的亲脂性更强的形式，具备独特的生物活性。
T64423	(Z)-[2,3’-Biindolinylidene]-2’,3-dione
	(Z)-[2,3’-Biindolinylidene]-2’,3-dione 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64423，CAS号为 906748-38-7。
T125873	(Z)-3-Hydroxy-5-methoxystilbene
	(Z)-3-Hydroxy-5-methoxystilbene 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125873。
T67667	Ethyl (Z)-3-aminobut-2-enoate
	Ethyl (Z)-3-aminobut-2-enoate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67667。
T83963	Z-DEVD-FMK Caspase-3 Inhibitor
	Z-DEVD-FMK Caspase-3 Inhibitor 是一种可渗透细胞膜的、不可逆的 caspase-3/CPP32 抑制剂，能够抑制肿瘤细胞的凋亡。在动物体内，它在大鼠发作后的海马区具有神经保护作用，且显著减少创伤后的细胞凋亡，并在诱发的大鼠创伤性脑损伤之前和之后改善神经学恢复情况。
T124104	3-O-(2'E,4'Z-Decadienoyl)ingenol
	3-O-(2'E,4'Z-Decadienoyl)ingenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124104。
T124424	3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol
	3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124424。
T125709	3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol
	3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125709。
T126203	1,2-Dinor-3-oxo-6,10-farnesadien-14-oic acid; Z-Fo
	1,2-Dinor-3-oxo-6,10-farnesadien-14-oic acid; Z-Fo 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126203，CAS号为 1217271-08-3。
T10177	(5Z,2E)-CU-3	Apoptosis	Apoptosis
	(5Z,2E)-CU-3 是一种具有有效性和选择性的 DGKα 同工酶抑制剂，IC50 值为 0.6 μM，通过对竞争ATP来抑制 DGKα，Km 值为 0.48 mM。(5Z,2E)-CU-3 具有选择性，靶向 DGKα 催化区域，但不作用于调节区域。(5Z,2E)-CU-3 具有抗肿瘤和免疫原性作用，促进癌细胞的凋亡和 T 细胞的活化。
T65586	(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
	(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65586，CAS号为 356068-93-4。
T38184	C18:1 3'-sulfo Galactosylceramide (d18:1/18:1(9Z)) C18:1 3'-sulfo Galactosylceramide (d18:1/18:1(9Z))
	C18:1 3'-sulfo Galactosylceramide is a member of the sulfatide class of glycolipids. It has been found in mouse brain. It has been used as a standard for the quantification of C18:1 3'-sulfo galactosylceramide in dried blood spots from patients with metachromatic leukodystrophy (MLD) by UPLC-MS.
T125738	2-[(1R,2R)-3-oxo-2-[(2Z)-5-(sulfooxy)pent-2-en-1-y
	2-[(1R,2R)-3-oxo-2-[(2Z)-5-(sulfooxy)pent-2-en-1-y 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125738，CAS号为 155408-18-7。
T65075	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate
	(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65075，CAS号为 17110-51-9。
T67386	Olanzapine Thiolactam Impurity
	(Z)-1-(4-(4-Methylpiperazin-1-yl)-2-thioxo-1H-benzo[b][1,4]diazepin-3(2H)-ylidene)propan-2-one 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67386。
T66986	(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine
	(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66986，CAS号为 767340-03-4。
T21617	MG-115 Z-LL-Nva-CHO	Proteasome	Proteases/Proteasome; Ubiquitination
	MG-115 (Z-LL-Nva-CHO) 是一种有效且可逆的蛋白酶体抑制剂，对20S 和26S 蛋白酶体的 Ki 值分别为 21 nM 和 35 nM。MG-115 特异性抑制蛋白酶体的胰凝乳蛋白酶样活性，诱导 p53 依赖性细胞凋亡。
T8799	(E/Z)-IT-603 IT603	Others; NF-κB	NF-κB; Others
	(E/Z)-IT-603 是一种c-Rel 抑制剂，其IC50=3 μM。它是 E-IT-603 和 Z-IT-603的混合物。它具有抗癌作用。它有望作为调节剂调节移植物抗宿主病和恶性病中的 T 细胞反应。
T60624	(E/Z)-AG490
	(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) 是异构体 (E)-AG490 和 (Z)-AG490 的外消旋体。(E)-AG490 是一种可抑制EGFR，Stat-3和JAK2/3的酪氨酸激酶抑制剂。
T38278	9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid
	9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic acid is an ω-3 very long-chain polyunsaturated fatty acid. It has been used to study the desaturation and elongation of ω-3 polyunsaturated fatty acids. It is elongated to form C26:5 or acted on by δ6 desaturase to form C24:6. 9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic acid is found at low levels in mouse brain and spleen and levels decrease in the brain and spleen of old and exceptionally old mice.
T37371	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid
	4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.
T80659	Z-YVAD-CMK	Caspase	Apoptosis; Proteases/Proteasome
	Z-YVAD-CMK为一种针对caspase-1及caspase-3的抑制剂。
T69491	(E/Z)-Ensifentrine
	(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effects. It is being developed by Verona Pharma as a potential treatment for asthma and hay fever, and is currently in clinical trials.
T37634	17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
	Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).
T67534	Z-Asn-OH
	Z-Asn-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67534，CAS号为 2304-96-3。
T67545	Z-Thr-OH
	Z-Thr-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67545，CAS号为 19728-63-3。
T65187	FMOC-D-LYS(Z)-OH
	FMOC-D-LYS(Z)-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65187，CAS号为 110990-07-3。
T61890	(E/Z)-BIO-acetoxime
	(E/Z)-BIO-acetoxime 是有效的，选择性的GSK-3α/β 抑制剂。对于GSK-3α/β，CDK5/p25，CDK2/cyclin A 和CDK1/cyclin B 的IC50分别为10nM，2.4μM, 4.3μM, 63μM。
T36999	7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
	Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to b...
T74044	Z-Pro-prolinal
	Z-Pro-prolinal (N-Benzyloxycarbonyl-L-prolyl-L-prolinal) 是一种特异的，具有口服活性的脯氨酰寡肽酶 (PREP) 抑制剂，对于猪 PREP 的 IC50为 0.4 nM。
T76232	Z-DEVD-AMC
	Z-DEVD-AMC 是一种选择性 caspase-3 底物，可通过荧光光谱法测量。 AMC 可用作基于 AMC 的酶底物 (包括基于 AMC 的半胱天冬酶底物) 的荧光参考标准。
T61379	Anticancer agent 30
	Anticancer agent 30 (compound 6f-Z) is a potent anticancer compound. It belongs to the class of 3-arylidene-2-oxindole derivatives and acts as a selective inhibitor of CDK2. Extensive research has demonstrated its significant anticancer activity, making it a promising candidate for cancer treatment [1].
T78119	Z-L(D-Val)G-CHN2	HSV	Microbiology/Virology
	Z-L(D-Val)G-CHN2（即Z-LVG-CHN2）是半胱氨酸蛋白酶抑制剂的异构体，作为一种三肽衍生物，模仿了人体半胱氨酸蛋白酶结合中心的部分结构。它可以抑制HSV，并且能有效阻断SARS-COV-2的3CL pro蛋白酶，从而抑制病毒活性（EC50=190 nM），但对脊髓灰质炎病毒复制无显著作用。
T83761	12-oxo-9(Z)-Dodecenoic Acid 12-oxo-9-cis-Dodecenoic Acid,12-keto-9Z-Dodecenoic Acid
	12-oxo-9(Z)-Dodecenoic acid 是一种 ω-oxoacid 和 ω-6 PUFA 亚麻酸及ω-3 PUFA α-亚麻酸的代谢产物。通过植物中的脂氧合酶产生的13-羟基过氧化物中间体，由过氧化物裂解酶形成。12-oxo-9(Z)-Dodecenoic acid (100 µM) 对植物病原真菌 P. parasitica 有活性。
T21783	AG-183
	(Z)-Tyrphostin A51 是 Lanoconazole A51 的 Z 构型形式。Tyrphostin A51 是一种有效的蛋白酪氨酸激酶 (PTK)抑制剂，以剂量依赖性方式抑制原代星形胶质细胞培养物中 [3H]牛磺酸的体积敏感释放。Tyrphostin A51 显着降低细胞酪氨酰磷酸化水平。Tyrphostin A51 抑制基础和 EGF 诱导的人骨细胞增殖。
T36077	cis-Parinaric Acid cis-Parinaric Acid,α-Parinaric Acid
	cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical rainforest tree indigenous to Fiji. Makita seeds are inedible, and this toxicity may be due at least in part to the unstable conjugated fatty acids, including cis-parinaric acid, contained wit...

化合物

JAK2 Inhibitor V

Cat.No: T3042

Synonym: JAK2 Inhibitor V Z3,Z3

Target: JAK

Cat.No: T6005

Synonym: Caspase-3 Inhibitor

Target: Caspase

cis-Urocanic acid

Cat.No: T10824

Synonym: cis-UCA,(Z)-Imidazole-4-acrylic acid,(Z)-Urocanic acid,(E)-Urocanic acid,(Z)-3-(1H-Imidazol-5-yl)acrylic acid,顺式-尿刊酸

Target: 5-HT Receptor

(E/Z)-Zotiraciclib

Cat.No: T21503

Synonym: (E/Z)-TG02,(E/Z)-SB1317

Target: FLT, JAK, CDK

(E/Z)-GSK-3β inhibitor 1

Cat.No: T9178

Synonym: GSK-3β inhibitor 1

Target: GSK-3

(Z)-2-Bromo-3-methyl-2-butenedioic acid

Cat.No: T39869

Synonym: cis-2-Bromo-3-methylbutenendioic acid,(Z)-2-溴-3-甲基-2-丁二酸

N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone

Cat.No: T37336

Flupentixol dihydrochloride

Cat.No: T5135

Synonym: 盐酸氟哌噻吨,Fupentixol Dihydrochloride,Flupenthixol dihydrochloride,(E/Z)-Flupentixol Dihydrochloride

Target: Dopamine Receptor

Z-1,2-Dimethoxy-4-(3-fluoro-2-propenyl)benzene

Cat.No: T35291

Cat.No: T12302

Synonym: (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide

Target: Endogenous Metabolite

Cat.No: T2340

Target: Tyrosinase

Cat.No: T12628

Synonym: (S,R,S)-(-)-MG-132,N-[(苯基甲氧基)羰基]-L-亮氨酰-N-[(1S)-1-甲酰基-3-甲基丁基]-D-亮氨酰胺,Z-Leu-D-leu-leu-al

Target: Proteasome

methyl (Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate

Cat.No: T60059

Cat.No: T30626

Synonym: Z-1159-3

omega-3 Arachidonic acid ethyl ester

Cat.No: T81609

Synonym: (all-Z)-8,11,14,17-Eicosatetraenoic acid ethyl ester,ω-3 Arachidonic acid ethyl ester

(Z)-[2,3’-Biindolinylidene]-2’,3-dione

Cat.No: T64423

(Z)-3-Hydroxy-5-methoxystilbene

Cat.No: T125873

Ethyl (Z)-3-aminobut-2-enoate

Cat.No: T67667

Z-DEVD-FMK Caspase-3 Inhibitor

Cat.No: T83963

3-O-(2'E,4'Z-Decadienoyl)ingenol

Cat.No: T124104

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol

Cat.No: T124424

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol

Cat.No: T125709

1,2-Dinor-3-oxo-6,10-farnesadien-14-oic acid; Z-Fo

Cat.No: T126203

Cat.No: T10177

Target: Apoptosis

(Z)-5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid

Cat.No: T65586

C18:1 3'-sulfo Galactosylceramide (d18:1/18:1(9Z))

Cat.No: T38184

Synonym: C18:1 3'-sulfo Galactosylceramide (d18:1/18:1(9Z))

2-[(1R,2R)-3-oxo-2-[(2Z)-5-(sulfooxy)pent-2-en-1-y

Cat.No: T125738

(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl (Z)-octadec-9-en-1-yl carbonate

Cat.No: T65075

Olanzapine Thiolactam Impurity

Cat.No: T67386

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

Cat.No: T66986

Cat.No: T21617

Synonym: Z-LL-Nva-CHO

Target: Proteasome

Cat.No: T8799

Synonym: IT603

Target: Others, NF-κB

Cat.No: T60624

9(Z),12(Z),15(Z),18(Z),21(Z)-Tetracosapentaenoic Acid

Cat.No: T38278

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid

Cat.No: T37371

Cat.No: T80659

Target: Caspase

(E/Z)-Ensifentrine

Cat.No: T69491

17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Cat.No: T37634

Cat.No: T67534

Cat.No: T67545

FMOC-D-LYS(Z)-OH

Cat.No: T65187

(E/Z)-BIO-acetoxime

Cat.No: T61890

7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid

Cat.No: T36999

Cat.No: T74044

Cat.No: T76232

Anticancer agent 30

Cat.No: T61379

Z-L(D-Val)G-CHN2

Cat.No: T78119

Target: HSV

12-oxo-9(Z)-Dodecenoic Acid

Cat.No: T83761

Synonym: 12-oxo-9-cis-Dodecenoic Acid,12-keto-9Z-Dodecenoic Acid

Cat.No: T21783

cis-Parinaric Acid

Cat.No: T36077

Synonym: cis-Parinaric Acid,α-Parinaric Acid

Cat. No.	Product Name	Target	Signaling Pathways
TN2326	(Z)-Butylidenephthalide (Z)-3-Butylidenephthalide	Glucosidase	Metabolism
	(Z)-Butylidenephthalide ((Z)-3-Butylidenephthalide) 具有抗肿瘤和降血糖作用，能有效抑制胶质瘤的肿瘤生长，抑制 R-葡萄糖苷酶活性。
T5598	cis-3-Hexenyl hexanoate	Others	Others
	cis-3-Hexenyl hexanoate 存在于某些水果中，具有强烈的弥漫果香。
TN6362	(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one
	(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6362，CAS号为 856007-75-5。
T4867	Erucic acid Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid	PI3K; Endogenous Metabolite	Metabolism; PI3K/Akt/mTOR signaling
	Erucic acid (13(Z)-Docosenoic Acid) 是单不饱和脂肪酸，分离自萝卜的种子。Erucic acid 可以容易地穿过血脑屏障，使大脑中长链脂肪酸的积累正常化。Erucic acid 能够改善认知障碍并有效预防痴呆。
T5S1285	(+)-(3R,8S)-Falcarindiol Falcarindiol,镰叶芹二醇	Others	Others
	(+)-(3R,8S)-Falcarindiol 是一种从胡萝卜中得到的聚乙炔，有抗炎、抗肿瘤和抗脂质过氧化活性。它具有抗分歧杆菌作用，对Mycobacterium tuberculosisH37Ra 的 MIC 和 IC50值分别为 24 μM 和 6 μM。
TN3255	7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone	Others	Others
	7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone shows diacylglycerol acyltransferase (DGAT)1 inhibition with IC(50) values of 47.0 microM (for rat liver microsomes) and 160.7 microM (for HepG2 cell microsomes),
T83660	3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic Acid C18:5 n-3,C18:5(3Z,6Z,9Z,12Z,15Z),all-cis-3,6,9,12,15-Octadecapentaenoic Acid
	3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic acid 是一种在 G. kowalevskii 中发现的微藻 PUFA，常作为微藻和甲藻的化学分类生物标志物使用。
T6212	Combretastatin A4 CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09	Microtubule Associated	Cytoskeletal Signaling
	Combretastatin A4 (CA4) 是一种微管靶向剂，可结合 β-tubulin，Kd 值为 0.4 μM。
TCP2830	Neryl acetate Nerol acetate,Acetic acid neryl ester,(Z)-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯,cis-Geranyl acetate	Others	Others
	Neryl acetate (Acetic acid neryl ester) 是一种分离自柑桔油中的物质。
T22295	cis-3-Hexen-1-ol 叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol	Others	Others
	cis-3-Hexen-1-ol ((Z)-3-Hexen-1-ol) 是发现于许多新鲜水果和蔬菜中的一种绿色草味化合物，常用作加工食品的附加风味剂，以提供新鲜的绿色品质，也是多种昆虫的引诱剂。
T83514	(Z,Z)-3,13-Octadecadienyl acetate
	(Chemical name)为从雌性(S.bicingulata scientific name)的信息素腺提取物中分离的化合物，对吸引该物种雄性个体至关重要，且常用作诱捕雄蛾的诱饵。
TN2276	Tokinolide B	Others	Others
	Tokinolide B may have sedative and spasmolytic properties.
T39386	(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid
	(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid, a lanostane triterpenoid, demonstrates significant inhibitory effects on nitric oxide (NO) production in BV-2 microglia cells induced by n LPS, with an IC50 value of 9.55 uM. Moreover, this compound possesses anti-inflammatory properties.
T83517	(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate
	(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate (compound 7a) 是一种特定立体化学配置的二萜类化合物。
T5574	Guggulsterone Guggulsterone E&Z,香胶甾酮	Apoptosis; FXR; Akt; Caspase; JNK; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; Metabolism; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Guggulsterone (Guggulsterone E&Z) E&Z 是来自Commiphora wightii 树中树胶脂的植物甾醇。它通过下调抗细胞凋亡基因产物，调节细胞周期蛋白，激活caspases，JNK，抑制Akt，抑制多种肿瘤细胞的生长并诱导细胞凋亡。它是法尼醇 X 受体拮抗剂，可降低 CDCA 诱导的 FXR 活化。
TN1909	Malvidin-3-glucoside chloride 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride	Others	Others
	Malvidin-3-glucoside chloride (Oenin chloride) 是一种主要的葡萄酒花青素，能够调节大脑突触可塑性和外周炎症，促进应激反应的发生。
T38330	Collinin
	Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Collinin inhibits LPS-induced nitric oxide (NO) production (IC50 = 5.9 μM) and reduces COX-2 protein levels in RAW 264.7 cells.2 It completely inhibits aggregation of isolated rabbit platelets induced by arachidonic acid , collagen, or platelet activating factor (PAF) when used at a...
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...
T37451	Stachybotrysin B
	Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively).2 \|1. Zhao, J., Feng, J., Tan, Z., et al. Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J. Nat. Prod. 80(6), 1819-1826 (2017).\|2. Ma, X.-h., Zhen...
T36448	(E)-Ajoene
	(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Ant...

天然产物

(Z)-Butylidenephthalide

Cat.No: TN2326

Synonym: (Z)-3-Butylidenephthalide

Target: Glucosidase

cis-3-Hexenyl hexanoate

Cat.No: T5598

Target: Others

(Z)-5-Hydroxy-1,7-diphenylhept-4-en-3-one

Cat.No: TN6362

Cat.No: T4867

Synonym: Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid

Target: PI3K, Endogenous Metabolite

(+)-(3R,8S)-Falcarindiol

Cat.No: T5S1285

Synonym: Falcarindiol,镰叶芹二醇

Target: Others

7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone

Cat.No: TN3255

Target: Others

3(Z),6(Z),9(Z),12(Z),15(Z)-Octadecapentaenoic Acid

Cat.No: T83660

Synonym: C18:5 n-3,C18:5(3Z,6Z,9Z,12Z,15Z),all-cis-3,6,9,12,15-Octadecapentaenoic Acid

Combretastatin A4

Cat.No: T6212

Synonym: CA4,康普瑞汀,Z)-3,4,5,4',-四甲氧基-3'-羟基二苯乙烯,CRC 87-09

Target: Microtubule Associated

Cat.No: TCP2830

Synonym: Nerol acetate,Acetic acid neryl ester,(Z)-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯,cis-Geranyl acetate

Target: Others

cis-3-Hexen-1-ol

Cat.No: T22295

Synonym: 叶醇,Leaf alcohol,(Z)-3-Hexen-1-ol

Target: Others

(Z,Z)-3,13-Octadecadienyl acetate

Cat.No: T83514

Cat.No: TN2276

Target: Others

(3β,7β,12β,20Z)-3,7,12-Trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid

Cat.No: T39386

(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate

Cat.No: T83517

Cat.No: T5574

Synonym: Guggulsterone E&Z,香胶甾酮

Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy

Malvidin-3-glucoside chloride

Cat.No: TN1909

Synonym: 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride

Target: Others

Cat.No: T38330

Cat.No: T37452

Stachybotrysin B

Cat.No: T37451

Cat.No: T36448

Cat.No: T35750

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