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103

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T9770 Samelisant

SUVN-G3031

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
Samelisant (SUVN-G3031) 是 H3 受体的特异性反向激动剂,对人和大鼠的 Kis 分别为 8.7 nM 和 9.8 nM。 Samelisant 具有抗猝倒作用,可用于关于发作性睡病的研究。
T34752 Samelisant dihydrochloride

SUVN-G3031,SUVN-G 3031,SUVN G3031,SUVN-G3031 HCl

Samelisant dihydrochloride (SUVN-G3031) is a antagonist of histamine H3 receptor with potential for the treatment of cognitive impairment, dementia, attention deficit hyperactivity disorder, epilepsy, sleep disorders, obesity, schizophrenia, eating disorders, and pain.
T26187 Sesamex

AI3-20871,AI320871,AI3 20871

Sesamex is used as an insecticide.
T30785 Cefacetrile

Cefacetrilum,Cefacetrilo,Celospor,Cephacetrile,Cefacetril

Antibiotic Microbiology/Virology
Cefacetrile (Cephacetrile) 是一种广谱的头孢类抗生素,具有抗菌活性,可用于研究革兰氏菌感染,作用与头孢噻吩作用。
T0489 Flutamide

SCH 13521,氟他胺

Androgen Receptor Endocrinology/Hormones
Flutamide (SCH 13521) 是一种抗雄激素化合物,在啮齿动物和犬科动物中的效力与环丙孕酮大致相同。
T25210 CBHcy

Transferase Metabolism
CBHcy 是一种双底物类似物,是一种特异性 BHMT 抑制剂,可使甜菜碱-同型半胱氨酸 S-甲基转移酶 (BHMT) 采用与三元配合物相同的构象,可能会诱导半胱氨酸血症的发生。
T19450 N-desmethyl Enzalutamide

4-[3-[4-氰基-3-(三氟甲基)苯基]-5,5-二甲基-4-氧代-2-硫代-1-咪唑烷基]-2-氟苯甲酰胺,N-desmethyl MDV 3100

Androgen Receptor Endocrinology/Hormones
N-desmethyl Enzalutamide (N-desmethyl MDV 3100) 是一种 Enzalutamide 的主要活性代谢物,具有与 Enzalutamide 相似的一级和二级药效功效,并在与 Enzalutamide 大致相同的血浆浓度下循环。
T1667 Tandutinib

MLN518,CT53518,NSC726292,坦度替尼

Apoptosis; FLT; CSF-1R; PDGFR; Src; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Tandutinib (CT53518) 是一种选择性 FLT3抑制剂,其 IC50为 0.22 μM。它还抑制c-Kit 和PDGFR,其IC50分别为 0.17 μM 和 0.20 μM。它可穿透血脑屏障,用于急性骨髓性白血病。
T37173 MPro Inhibitor 11a

MProinhibitor 11a is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (MPro; IC50= 0.053 μM in a TR-FRET assay).1It reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 cells (EC50= 0.53 μM). MProinhibitor 11a also reduces viral RNA copy numbers in the same model when used at concentrations ranging from 1.85 to 50 μM. 1.Dai, W., Zhang, B., Jiang, X.-M., et al.Structure-based design of antiviral drug candidates targeting the SARS-...
TP1245L ACTH 4-11 acetate

ACTH 4-11 acetate (67224-41-3 Free base)

Others Others
ACTH 4-11 acetate 是一种促肾上腺皮质激素片段,具有与 α-黑素细胞刺激素 (MSH) 相同的氨基酸序列。 ACTH 4-11 acetate 仅在高剂量时表现出微弱的 MSH 效力。
T1545 Levamlodipine

左旋氨氯地平,(S)-Amlodipine,S-amlodipine

Calcium Channel Membrane transporter/Ion channel; Metabolism
Levamlodipine (S-amlodipine) 是一种二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压和心绞痛的研究。
TP1085L Neuromedin N acetate(92169-45-4 free base)

Neuromedin N (rat, mouse, porcine, canine) acetate

Dopamine Receptor GPCR/G Protein; Neuroscience
Neuromedin N acetate(92169-45-4 free base) 是一种神经肽,其衍生自与神经降压素相同的前体多肽,具有相似但略有不同的表达和作用。Neuromedin N 是多巴胺 D2 受体激动剂与大鼠新纹状体膜结合的有效调节剂。
T22530 6-Chloromelatonin

Melatonin Receptor; Dopamine Receptor GPCR/G Protein; Neuroscience
6-Chloromelatonin 是一种有效的褪黑素受体 (melatonin receptor) 激动剂,是一种5-甲氧基吲哚化合物,可竞争兔视网膜中相同的突触前褪黑激素受体位点 ,可抑制[3H]多巴胺的钙依赖性释放 具有比褪黑素更高的代谢稳定性。6-Chloromelatonin 竞争 [3H] 褪黑素 与 MT2 受体结合 (pKi=9.77),可能用于研究与抑郁症相关的失眠和睡眠障碍。
T37424 CAY10781

CAY10781

Others Others
CAY10781 是一种神经纤毛蛋白-1 (NRP-1) 和 VEGF-A.1 之间蛋白质-蛋白质相互作用的抑制剂。当使用浓度为 12.5 μM 时,它可抑制 43% 的相互作用。 当以相同浓度使用时,CAY10781 还抑制 VEGF-A 诱导的儿茶酚胺 A 分化 (CAD) 细胞中 VEGFR2 的磷酸化。
T27673 JNJ-26990990

Others Others
JNJ-26990990 是一种广谱抗惊厥药,是上市药物托吡酯的第二代后续药物。它被设计成具有与托吡酯相同的抗惊厥作用,但没有与托吡酯的碳酸酐酶抑制相关的副作用。它还具有治疗炎症性疼痛、神经性疼痛和抑郁症的潜在用途。
T4284 Levamlodipine besylate

左旋氨氯地平,(S)-Amlodipine Besylate (103129-82-4(free base))

Calcium Channel Membrane transporter/Ion channel; Metabolism
Levamlodipine besylate ((S)-Amlodipine Besylate(103129-82-4(free base))) 是一种二氢吡啶钙通道阻滞剂,具有舒张血管的作用,可用于高血压和心绞痛的研究。
T36466 Chlorin E6

Ce6,Chlorin e6,CE6

Parasite Microbiology/Virology
Chlorin E6 (CE6) 是一种第二代光敏剂,在与辐照结合使用时具有抗肿瘤活性。在植入性纤维肉瘤的小鼠模型中,Chlorin E6(2.5-10 毫克/千克,静脉注射,50-200 焦耳/平方厘米的辐照)在不同程度的辐照后会导致肿瘤完全消失。在一项针对支气管源性早期浅表鳞状细胞癌患者的 I 期临床研究中,对包括 Chlorin E6 在内的制剂进行了测试,结果良好(40 毫克/平方米,静脉注射,100 焦耳/平方厘米的激光辐照)。在一项针对早期肺癌患者的二期临床试验中,同样的给药模式使 82.9% 的患者获得了完全应答。Chlorin E6 已被研究为一种纳米技术给药工具。
T4978 Sarpogrelate hydrochloride

盐酸沙格雷酯,MCI-9042

5-HT Receptor GPCR/G Protein; Neuroscience
Sarpogrelate hydrochloride (MCI-9042) 是一种选择性5-HT2R 拮抗剂,可用于研究与血栓形成有关的血管疾病,对 5-HT2A、5-HT2B 和 5-HT2C 受体的pKi 值分别为 8.52、6.57 和 7.43。
T24537 N-Methylquipazine

NMethylquipazine,J366.838J,N-Methylquipazine;NMethylquipazine,N-Methylquipazine

N-Methylquipazine is an agonist of 5-HT3. It has almost the same affinity for 5-HT3 sites as quipazine.
T20492 Tetragastrin

Cholecystokinin tetrapeptide,Gastrin tetrapeptide

Tetragastrin is the C-terminal tetrapeptide of gastrin. It has the same physiological and pharmacological activity as gastrin.
T33064 Lysine valproate

Lysine valproate has same effect on brain GABA levels as sodium valproate.
T34619 Serratanine

Serratanine is a mixture of serratanine A & serratanine B; serratanine A same as lucidine B; serratanine B same as oxolucidine B.
T23943 DA 4643

DA-4643,DA4643

DA 4643 is one of the histamine H2-receptor antagonists. Both mifentidine and DA 4643 interact with the histamine H2-receptor at the same site, utilizing in the binding process the same, or closely similar, receptor structural features.
T14940 CGP11952

Others Others
CGP11952 is same the benzodiazepines in its pharmacological action and it also is an experimental benzodiazepine derivative.
T34819 Tetragastrin HCl

Trp-Met-Asp-Phe hydrochloride,Tetragastrin hydrochloride

Tetragastrin HCl is the HCl salt of Tetragastrin, the C-terminal tetrapeptide of gastrin. It has the same physiological and pharmacological activity as gastrin.
T28320 PD 121373

PD121373,PD-121373

PD 121373 is a Benzothiopyrano-indazole cpd. The benzothiopyranoindazoles are potent inhibitors of nucleic acid synthesis, reducing both DNA and RNA synthesis to the same extent at similar concentrations.
T71290 EVT-101 HCl

EVT-101 is a GluN2B antagonist, binding at the same GluN1/GluN2B dimer interface as ifenprodil but adopting a remarkably different binding mode involving a distinct subcavity and receptor interactions.
T69267 Naproxen glucuronide

Naproxen glucuronide is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a nonselective COX inhibitor.
T29651 Ademetionine, (S)-

Ademetionine (S-adenosylmethionine; SAMe) is a ubiquitous metabolite present in all cells and biological fluids, and serves as a methyl donor in a multitude of different methylation reactions involving proteins, phospholipids, catecholamines and DNA.
T27379 FR-194921

FR194921

FR-194921 is a potent, selective, and orally active antagonist for central adenosine A1 receptors with cognitive-enhancing and anxiolytic activity. FR194921 has same binding affinity profile among human, rat, and mouse.
T68441 SABRAC

SABRAC inhibits acid ceramidase in PC3 MC metastatic prostate cancer cells (IC50 = <1 µM), as well as induces accumulation of ceramides in the same cells.
TP1085 Neuromedin N

Neuromedin N (rat, mouse, porcine, canine)

Neuromedin N is a neuropeptide derived from the same precursor polypeptide as neurotensin, and with similar but subtly distinct expression and effects.
T69474 Naproxen ethyl ester

Naproxen ethyl ester is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness. It is a non-selective COX inhibitor.
T36837 (E,Z)-2-propyl-2-Pentenoic Acid

(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.
T37697 D-GsMTx4

D-GsMTx4

TRPC1/6 and Piezo2 inhibitor. Exhibits same effect as L-enantiomer, GsMTx4 (Cat. No. 4912) on TRPC channels. Inhibits mechanosensitive currents by ~70%. Protects against myocardial infarction in mouse ischemia/reperfusion model. Resistant to proteolytic digestion.
T34558 SC-48274

SC 48274,SC48274

SC-48274是一种新型抗焦虑药。SC-48274具有与丁螺环酮相同效力的抗焦虑活性,并且需要重复剂量给药来诱导抗焦虑活性。
T20266 Tetrasodium glutamate diacetate

Tetrasodium glutamate diacetate is a multi-purpose chelating agent and preservative booster. Tetrasodium Glutamate Diacetate serves the same function in formulations as EDTA. Tetrasodium Glutamate Diacetate is made from plant material, readily biodegradab
TP1377 Caerulein, desulfated TFA (20994-83-6 free base)

Caerulein, desulfated TFA

Caerulein, desulfated TFA is Caerulein after desulfurization.Caerulein is a deceptide with the same five carboxy-terminating amino acids as gastrin and cholecystatin (CCK)..
T26930 BW-1370U87

1370U 87,1370U-87,1370U87,BW 1370U87

BW-1370U87 is a monoamine oxidase A (MAO-A) inhibitor. BW-1370U87 elevates neurotransmitter amines in the brain over the same dose range at which it exhibits positive activities in animal models of depressive illness. BW-1370U87's mechanism of action foll
TP1547 Caerulein, desulfated

Caerulein, desulfated is the desulfurated form of Caerulein. Caerulein is a deceptide with the same five carboxy-terminal amino acids as gastrin and cholecystatin (CCK).
T81450 PKCε Inhibitor Scramble Peptide

PKCε Inhibitor Scramble Peptide为一Scramble肽,其氨基酸序列与PKCε抑制肽相同。
TP1075 AUNP-12 TFA (1353563-85-5 free base)

AUNP-12 TFA,NP-12 TFA

AUNP-12 TFA (NP-12 TFA) is a polypeptide antagonist in the pd-1 signaling pathway, which has the same antagonistic effect on pd-l1 and pd-l2, and can protect the proliferation and effector function of lymphocytes.
T6666 Sevelamer Carbonate

Others Others
Sevelamer carbonate 是一种口服具有活力的非钙基磷酸盐结合剂,能有效降低体内血清磷水平,但对体内血清钙、氯水平影响极小,可用于研究慢性肾脏病的高磷血症。它被认为是七氟乙烯的一种改进的缓冲形式。
T79919 S-Adenosyl-L-methionine (1,4-butanedisulfonate)

Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)

Endogenous Metabolite Metabolism
S-Adenosyl-L-methionine (S-Adenosyl methionine) 1,4-butanedisulfonate 作为一种口服活性的甲基供体,它是一种膳食补充剂,对抗抑郁和缓解疼痛具有显著功效。此化合物在癌症治疗中显示了抗增殖、促进凋亡和阻止转移的潜在作用。同时,S-Adenosyl-L-methionine 1,4-butanedisulfonate 也用于肝病和骨关节炎的相关研究。
T33673 Niludipine

Niludipina,BAY-a 7168,Bay a 7168,Niludipinum

Nirudipine is a double (2-propoxyethyl) analogist of nifedipine and a calcium channel blocker, which is also a safe anti-angina Ca2+ antagonist with a broad range of efficacy for all types of angina. At the same time, Niludipine is a highly effective drug
T25910 Oxilorphan

Oxilorfano,Oxilorphane,Bristol laboratories BC 2605,levo-BC-2605

Oxilorphan acts as a μ-opioid receptor (MOR) antagonist but a κ-opioid receptor (KOR) partial agonist and has similar effects to naloxone and around the same potency as a MOR antagonist. Oxilorphan has some weak partial agonist actions at the MOR and can
T81625 Obestatin(human) TFA

Obestatin(human) TFA, 同源于与ghrelin相同的前体多肽,是一种内源性肽。该化合物抑制大鼠食欲并降低体重增加。
T1780L Parecoxib sodium

SC 69124A,SC-69124A,帕瑞昔布钠,SC69124A,Dynastat

Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib and r
TP1552 TLQP-30

Chronic intracerebroventricular (ICV) injection of a VGF peptide named TLQP-21 increased resting energy expenditure and temperature in mice. Furthermore, in mice fed a high-fat diet, the same peptide prevented the increase in body and white adipose tissue
T70944 Carotegrast methyl HCl

Carotegrast methyl, also known as AJM300 and PTC-100, is an orally-active small molecule that antagonises the α4 integrin receptor. AJM300 reduces inflammation by blocking leucocyte trafficking. Oral treatment with AJM300 dose-dependently inhibited lymphocyte homing to Peyer's patches and increased the peripheral lymphocyte count in the same dose range. AJM300 dose-dependently prevented the development of experimental colitis in mice.

化合物

Samelisant
Cat.No: T9770
Synonym: SUVN-G3031
Target: Histamine Receptor
Samelisant dihydrochloride
Cat.No: T34752
Synonym: SUVN-G3031,SUVN-G 3031,SUVN G3031,SUVN-G3031 HCl
Target:
Sesamex
Cat.No: T26187
Synonym: AI3-20871,AI320871,AI3 20871
Target:
Cefacetrile
Cat.No: T30785
Synonym: Cefacetrilum,Cefacetrilo,Celospor,Cephacetrile,Cefacetril
Target: Antibiotic
Flutamide
Cat.No: T0489
Synonym: SCH 13521,氟他胺
Target: Androgen Receptor
CBHcy
Cat.No: T25210
Synonym:
Target: Transferase
N-desmethyl Enzalutamide
Cat.No: T19450
Synonym: 4-[3-[4-氰基-3-(三氟甲基)苯基]-5,5-二甲基-4-氧代-2-硫代-1-咪唑烷基]-2-氟苯甲酰胺,N-desmethyl MDV 3100
Target: Androgen Receptor
Tandutinib
Cat.No: T1667
Synonym: MLN518,CT53518,NSC726292,坦度替尼
Target: Apoptosis, FLT, CSF-1R, PDGFR, Src, c-Kit
MPro Inhibitor 11a
Cat.No: T37173
Synonym:
Target:
ACTH 4-11 acetate
Cat.No: TP1245L
Synonym: ACTH 4-11 acetate (67224-41-3 Free base)
Target: Others
Levamlodipine
Cat.No: T1545
Synonym: 左旋氨氯地平,(S)-Amlodipine,S-amlodipine
Target: Calcium Channel
Neuromedin N acetate(92169-45-4 free base)
Cat.No: TP1085L
Synonym: Neuromedin N (rat, mouse, porcine, canine) acetate
Target: Dopamine Receptor
6-Chloromelatonin
Cat.No: T22530
Synonym:
Target: Melatonin Receptor, Dopamine Receptor
CAY10781
Cat.No: T37424
Synonym: CAY10781
Target: Others
JNJ-26990990
Cat.No: T27673
Synonym:
Target: Others
Levamlodipine besylate
Cat.No: T4284
Synonym: 左旋氨氯地平,(S)-Amlodipine Besylate (103129-82-4(free base))
Target: Calcium Channel
Chlorin E6
Cat.No: T36466
Synonym: Ce6,Chlorin e6,CE6
Target: Parasite
Sarpogrelate hydrochloride
Cat.No: T4978
Synonym: 盐酸沙格雷酯,MCI-9042
Target: 5-HT Receptor
N-Methylquipazine
Cat.No: T24537
Synonym: NMethylquipazine,J366.838J,N-Methylquipazine;NMethylquipazine,N-Methylquipazine
Target:
Tetragastrin
Cat.No: T20492
Synonym: Cholecystokinin tetrapeptide,Gastrin tetrapeptide
Target:
Lysine valproate
Cat.No: T33064
Synonym:
Target:
Serratanine
Cat.No: T34619
Synonym:
Target:
DA 4643
Cat.No: T23943
Synonym: DA-4643,DA4643
Target:
CGP11952
Cat.No: T14940
Synonym:
Target: Others
Tetragastrin HCl
Cat.No: T34819
Synonym: Trp-Met-Asp-Phe hydrochloride,Tetragastrin hydrochloride
Target:
PD 121373
Cat.No: T28320
Synonym: PD121373,PD-121373
Target:
EVT-101 HCl
Cat.No: T71290
Synonym:
Target:
Naproxen glucuronide
Cat.No: T69267
Synonym:
Target:
Ademetionine, (S)-
Cat.No: T29651
Synonym:
Target:
FR-194921
Cat.No: T27379
Synonym: FR194921
Target:
SABRAC
Cat.No: T68441
Synonym:
Target:
Neuromedin N
Cat.No: TP1085
Synonym: Neuromedin N (rat, mouse, porcine, canine)
Target:
Naproxen ethyl ester
Cat.No: T69474
Synonym:
Target:
(E,Z)-2-propyl-2-Pentenoic Acid
Cat.No: T36837
Synonym:
Target:
D-GsMTx4
Cat.No: T37697
Synonym: D-GsMTx4
Target:
SC-48274
Cat.No: T34558
Synonym: SC 48274,SC48274
Target:
Tetrasodium glutamate diacetate
Cat.No: T20266
Synonym:
Target:
Caerulein, desulfated TFA (20994-83-6 free base)
Cat.No: TP1377
Synonym: Caerulein, desulfated TFA
Target:
BW-1370U87
Cat.No: T26930
Synonym: 1370U 87,1370U-87,1370U87,BW 1370U87
Target:
Caerulein, desulfated
Cat.No: TP1547
Synonym:
Target:
PKCε Inhibitor Scramble Peptide
Cat.No: T81450
Synonym:
Target:
AUNP-12 TFA (1353563-85-5 free base)
Cat.No: TP1075
Synonym: AUNP-12 TFA,NP-12 TFA
Target:
Sevelamer Carbonate
Cat.No: T6666
Synonym:
Target: Others
S-Adenosyl-L-methionine (1,4-butanedisulfonate)
Cat.No: T79919
Synonym: Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)
Target: Endogenous Metabolite
Niludipine
Cat.No: T33673
Synonym: Niludipina,BAY-a 7168,Bay a 7168,Niludipinum
Target:
Oxilorphan
Cat.No: T25910
Synonym: Oxilorfano,Oxilorphane,Bristol laboratories BC 2605,levo-BC-2605
Target:
Obestatin(human) TFA
Cat.No: T81625
Synonym:
Target:
Parecoxib sodium
Cat.No: T1780L
Synonym: SC 69124A,SC-69124A,帕瑞昔布钠,SC69124A,Dynastat
Target:
TLQP-30
Cat.No: TP1552
Synonym:
Target:
Carotegrast methyl HCl
Cat.No: T70944
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T4447 S-(5'-Adenosyl)-L-methionine tosylate

S-腺苷蛋氨酸对甲苯磺酸盐,SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt

Others Others
S-(5'-Adenosyl)-L-methionine tosylate (SAMe) 是一种普遍存在的甲基供体,参与多种生物反应,包括由 DNA 和蛋白质甲基转移酶介导的反应。它可改善抑郁、与骨关节炎和纤维肌痛相关的疼痛以及肝毒性。
T7475 S-Adenosyl-L-methionine

AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸

Others; Endogenous Metabolite Metabolism; Others
S-Adenosyl-L-methionine (Ademetionine) 是一种具有有效的抗抑郁和减轻疼痛作用的膳食补充剂,是通过蛋氨酸腺苷转移酶的作用由蛋氨酸和 ATP 内源性生产的,是一种重要的口服具有活力的甲基供体,能够用于肝病和骨关节炎的研究。
TN6087 Cassamedine

Cassamedine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6087,CAS号为 16408-75-6。
T3432 Cinobufagin

华蟾蜍精,华蟾酥毒基,Cinobufagine

Apoptosis; ATPase; Autophagy Apoptosis; Autophagy; Membrane transporter/Ion channel
Cinobufagin (Cinobufagine) 是一种具有抗肿瘤功效的天然产物。
TN2496 1,4-Anthraquinone

Others Others
1,4-Anthraquinone 是一种抗癌药物,在体外与柔红霉素相同纳摩尔范围内阻断核苷转运、抑制大分子合成、诱导 DNA 片段化并降低 L1210 白血病细胞的生长和活力。它被提议为一种用于高效液相色谱 (HPLC) 测定药物制剂中 N-乙酰半胱氨酸 (NAC) 和卡托普利 (CAP) 的新型柱前试剂。
T5S1172 Tiliroside

银椴甙,Tribuloside,银椴苷;椴树苷

Antioxidant oxidation-reduction
Tiliroside (Tribuloside) 是糖苷类黄酮,是 α-淀粉酶的非竞争性抑制剂(Ki:84.2 μM)。它抑制胃肠道中碳水化合物的消化和葡萄糖的吸收,具有抗糖尿病作用。
T2163 Dihydrocapsaicin

CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide

Others; TRP/TRPV Channel Membrane transporter/Ion channel; Others
Dihydrocapsaicin (CCRIS1589) 是一种天然来源的辣椒素,是TRPV1的选择性激动剂,同时可以增加 p-Akt 水平。它可以增强低温诱导的神经保护。
T37984 D-Fructose-1,6-bisphosphate sodium salt hydrate

Others Others
D-Fructose-1,6-bisphosphate sodium salt hydrate 是碳水化合物代谢的中间体,包括糖酵解和糖异生。在糖酵解过程中,它是由磷酸果糖激酶磷酸化果糖-6-磷酸产生的。由果糖-1,6-二磷酸酶-1介导的逆反应是糖异生的限速步骤之一。同样的反应也发生在植物的叶绿体中,D-Fructose-1,6-bisphosphate sodium salt hydrate 作为还原性戊糖磷酸循环的一部分。由于癌细胞采用糖酵解作为代谢能量产生的主要来源,这一途径已成为癌症化疗的主要靶点。
T25827 Monactin

Monactin is a Marcrotetrolide antibiotic produced by cycloheximide producing species of Streptomyces. It is a homolog of nonactin from the same species.
TN4427 Lethedioside A

Others Others
Lethedoside A was either inactive or weakly active against KB tumor cells, in contrast to previously isolated flavones from the same plant.
T75631 Ganorbiformin B

Ganorbiformin B是一种具有与灵芝酸相同羊毛甾烷骨架的羊毛甾烷三萜类化合物。其C-3差向异构体灵芝酸T对结核分枝杆菌H37Ra显示出强抗分枝杆菌活性。
T35577 Phosphatidylserines (bovine)

Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi...

天然产物

S-(5'-Adenosyl)-L-methionine tosylate
Cat.No: T4447
Synonym: S-腺苷蛋氨酸对甲苯磺酸盐,SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
Target: Others
S-Adenosyl-L-methionine
Cat.No: T7475
Synonym: AdoMet,Ademetionine,SAMe,S-Adenosyl methionine,S-腺苷-L-蛋氨酸
Target: Others, Endogenous Metabolite
Cassamedine
Cat.No: TN6087
Synonym:
Target:
Cinobufagin
Cat.No: T3432
Synonym: 华蟾蜍精,华蟾酥毒基,Cinobufagine
Target: Apoptosis, ATPase, Autophagy
1,4-Anthraquinone
Cat.No: TN2496
Synonym:
Target: Others
Tiliroside
Cat.No: T5S1172
Synonym: 银椴甙,Tribuloside,银椴苷;椴树苷
Target: Antioxidant
Dihydrocapsaicin
Cat.No: T2163
Synonym: CCRIS1589,二氢辣椒素,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
D-Fructose-1,6-bisphosphate sodium salt hydrate
Cat.No: T37984
Synonym:
Target: Others
Monactin
Cat.No: T25827
Synonym:
Target:
Lethedioside A
Cat.No: TN4427
Synonym:
Target: Others
Ganorbiformin B
Cat.No: T75631
Synonym:
Target:
Phosphatidylserines (bovine)
Cat.No: T35577
Synonym:
Target:
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