93
15
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11563 |
Histone Acetyltransferase Inhibitor II
|
Epigenetic Reader Domain; Histone Acetyltransferase | Chromatin/Epigenetic |
Histone Acetyltransferase Inhibitor II 是一种选择性的细胞渗透性 p300 组蛋白乙酰转移酶抑制剂,IC50值为 5 µM。它在哺乳动物细胞中具有抗乙酰化酶活性,可用于癌症研究。 | |||
T5052 |
Toltrazuril (sulfone)
Toltrazuril sulfone,妥曲珠利砜,Ponazuril |
Parasite | Microbiology/Virology |
Toltrazuril sulfone (Ponazuril) 是 Toltrazuril 的代谢物,是一种抗原生动物剂。它是一种三嗪类抗球虫剂,用于预防家禽球虫病。 | |||
T2562 |
Eltrombopag
SB-497115,SB-497115-GR,艾曲波帕 |
Thrombin | Proteases/Proteasome |
Eltrombopag (SB-497115-GR) 是一种具有巨核细胞生成刺激活性的口服活性血小板生成素受体激动剂,可结合并刺激血小板血小板生成素受体,用于血小板减少的某些病症研究。 | |||
T0870 |
Altrenogest
R2267,RU2267,Allyltrenbolone,A35957,烯丙孕素 |
Estrogen/progestogen Receptor; Progesterone Receptor | Endocrinology/Hormones; Others |
Altrenogest (Allyltrenbolone) 是一种结构与trenbolone 相关的孕激素,能作用于孕激素受体。 | |||
TN7093 |
N-Caffeoyltryptophan
trans-Caffeoyl-L-tryptophan,反式咖啡酰-L-色氨酸 |
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan) 是一种潜在的 Sirt 抑制剂,使用咖啡提取物进行筛选。 N-Caffeoyltryptophan 抑制 Sirt2 (IC50; 8.7 μM) 优于 Sirt1 (IC50; 34μM)。 | |||
T22981 |
Tetradecyltrimethylammonium bromide
MitMAB,Cetrimide,tetradecyl trimethyl ammonium bromide,十四烷基三甲基溴化铵 |
Dynamin | Cytoskeletal Signaling |
Tetradecyltrimethylammonium bromide (MitMAB) 是一种具有不对称结构的阳离子表面活性剂,是一种有机结构单元。 | |||
T21422 |
Methylnaltrexone bromide
Relistor,MOA-728,MOA 728,Methylnaltrexone,溴化甲基纳曲酮,MOA728 |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Methylnaltrexone bromide (MOA-728) 是纳曲酮的四元衍生物,是可口服的外周作用 μ 阿片拮抗剂。它穿越血脑屏障的能力有限,可在胃肠道组织中发挥作用。 | |||
T6825 |
Eltrombopag Olamine
Promacta Olamine,Revolade,艾曲泊帕乙醇胺盐,Eltrombopag diethanolamine salt,SB497115,艾曲波帕乙醇胺盐,SB-497115GR |
Thrombin | Proteases/Proteasome |
Eltrombopag Olamine (Eltrombopag diethanolamine salt) 是 Eltrombopag 的口服活性乙醇胺盐,是一种血小板生成素(TPO)受体激动剂,用于血小板减少的某些病症研究。 | |||
T77560 |
Histone acetyltransferase p300 Inhibitor 4c
|
Carbonic Anhydrase; AChE | Metabolism; Neuroscience |
Histone acetyltransferase p300 Inhibitor 4c 是2-氨基噻唑衍生物,Histone acetyltransferase p300 Inhibitor 4c 对 hCA I 、hCA II、AChE 和 BChE 具有抑制作用,Ki 值为 0.008 ± 0.001 、 0.124 ± 0.017、0.129 ± 0.030 和 0.083 ± 0.041 μM。 | |||
T1241 |
Altretamine
Hexamethylmelamine,NSC13875,六甲蜜胺,RB-1515,ENT-50852,WR-95704 |
DNA Alkylator/Crosslinker; DNA Alkylation | DNA Damage/DNA Repair |
Altretamine (ENT-50852) 是一种具有抗肿瘤活性的烷化剂。 | |||
T1061 |
Toltrazuril
BAY-i 9142,Toltrazurilo,妥曲珠利,Baycox,Toltrazurilum,托曲珠利 |
Antibiotic; Parasite | Microbiology/Virology |
Toltrazuril (Toltrazurilo) 是一种抗原虫剂,对球虫亚纲有效。 | |||
T9128 |
N-Desmethyltrimipramine
|
Others | Others |
N-Desmethyltrimipramine 是一种生化物质。 | |||
T20163 |
Acetyltrialanine
|
||
Acetyltrialanine 是一种二肽化合物,在 Tb+3-胰腺弹性蛋白酶复合物上的两个位点结合,可做为氮源使用。 | |||
T0963 |
Naltrexone hydrochloride
Depade,盐酸纳曲酮,Trexan,Naltrexone HCl,Antaxone |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Naltrexone hydrochloride (Naltrexone HCl) 是一种合成的 opiate 拮抗剂,用于预防 opiate 成瘾和酗酒的复发。 | |||
T15049 |
Daltroban
BM-13505,SKF 96148 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Daltroban (SKF 96148) (BM-13505) 是选择性和特异性的血栓素 A2 (TXA2) 受体拮抗剂。Daltroban 可以增加血管平滑肌细胞内钙。Daltroban 显示对再灌注损伤的保护作用。 | |||
T20540 |
N-Valyltryptophan
二肽-2,Val-trp,L-Valyl-L-tryptophan |
Others | Others |
N-Valyltryptophan (Val-trp) 是蛋白质分解代谢或蛋白质消化的不完全分解产物。 | |||
T8600 |
N-ACETYLTRYPTAMINE
|
Melatonin Receptor | GPCR/G Protein |
N-Acetyltryptamine 是视网膜褪黑素受体的部分激动剂,可用于 5-羟色胺 N-乙酰转移酶活性的检测。 | |||
T61037 |
Glycosyltransferase-IN-1
|
Others | Others |
Glycosyltransferase-IN-1 是一种糖基转移酶 (glycosyltransferase) 抑制剂,具有抑菌活性,抑制 MSSA、MRSA 、枯草杆菌和肠杆菌。 | |||
T7086 |
Tris(benzyltriazolylmethyl)amine
三[(1-苄基-1H-1,2,3-三唑-4-基)甲基]胺,TBTA |
Others | Others |
Tris(benzyltriazolylmethyl)amine (TBTA) 是一种能作为生化工具的配体,可用于标记蛋白质和酶。 | |||
T75421 | alpha-2,3-Sialyltransferase (PmST3) | ||
alpha-2,3-Sialyltransferase (PmST3) 是一种 β-半乳糖苷透过酶。alpha-2,3-Sialyltransferase (PmST3) 催化唾液酸转移至糖蛋白和糖脂的碳水化合物基团。 | |||
T13429 |
α-2,3-sialyltransferase-IN-1
Lith-O-Asp analog |
Others | Others |
α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM). | |||
T28883 |
Sultroponium
A118,A-118,A 118 |
||
Sultroponium may be used as an anticholinergic agent or antispasmodic. | |||
T72265 | Eltrombopag methyl ester | ||
Eltrombopag methyl ester,一种Eltrombopag衍生物,为促血小板生成素(Tpo)受体激动剂,旨在促进血小板生成,用于研究特定类型的血小板减少症。 | |||
T75411 | beta-1, 3-N-Acetylhexaminyltransferase (LgtA) | ||
Beta-1, 3-N-Acetylhexaminyltransferase (LgtA) 是一种糖基转移酶,在生化研究中常见。该酶主要催化作用为将 N-乙酰葡糖胺从 UDP-GlcNAc 转移到 N-乙酰乳糖胺和乳糖上。 | |||
T75415 | beta-1,3-Galactosyltransferase (CgtB) | ||
beta-1,3-Galactosyltransferase (CgtB) (GM1-synthase) 为生化研究中常用的酶,负责催化半乳糖分子的加成,以生产含有 GM1-like LOSSIAL 结构的唾液化低脂糖(LOSSIAL)。 | |||
T41039 |
Gel filtration medium G-100
|
||
Gel filtration medium G-100, a substance designed for protein purification, enables the separation and purification of proteins through gel filtration. | |||
T20163L |
Acetyltrialanine acetate
Acetyltrialanine acetate(19245-85-3 Free base) |
Others | Others |
Acetyltrialanine acetate 是鼠伤寒沙门氏菌突变体的氮源。 | |||
T79159 |
Methyl 12-methyltridecanoate
|
ROS Kinase | Tyrosine Kinase/Adaptors |
Methyl 12-methyltridecanoate ((R)-betaxolol hydrochloride) 是一种从Brevibacterium casei LS14中提取的生物表面活性剂,能够增强银纳米颗粒在生物体内环境中的兼容性,为其功能化开辟了新途径。 | |||
T38602 |
(E/Z)-Eltrombopag 13C4
(E/Z)-Eltrombopag 13C4,(E/Z)-SB-497115 13C4 |
||
(E/Z)-Eltrombopag 13C4 ((E/Z)-SB-497115 13C4) is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is a thrombopoietin (TPO) receptor agonist developed for certain conditions that lead to thrombocytopenia. | |||
T20008 |
Phenyltrimethylammonium tribromide
NSC87897,NSC 173340,NSC-173340,NSC 87897,NSC-87897 |
||
In Organic Synthesis, Phenyltrimethylammonium tribromide is a Versatile Reagent. | |||
T23041 |
N-Benzylnaltrindole hydrochloride
|
Others | Others |
δ2 opioid receptor antagonist | |||
T12169 |
Naltrindole hydrochloride
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Naltrindole hydrochloride 是一种选择性的非肽类 δ 阿片受体拮抗剂 (Ki = 0.02 nM)。 | |||
T30018 | Ammonium, (p-trimethylammonio)benzyltrimethyl-, diiodide | ||
Ammonium, (p-trimethylammonio)benzyltrimethyl-, diiodide is a bioactive chemical. | |||
T25067 | Altromycin G | ||
Altromycin G is a new pluramycin-like antibiotic. | |||
T25062 | Altromycin B | ||
Altromycin B is a new pluramycin-like antibiotic. | |||
T63738 | Purine phosphoribosyltransferase-IN-2 | ||
Purine phosphoribosyltransferase-IN-2 是一种有效的恶性疟原虫 (Pf),间日疟原虫 (Pv) 以及布氏锥虫 (Tbr) 6-氧嘌呤磷酸核糖基转移酶 (PRT) 抑制剂,他们的Ki 值分别为 30、20 和 2 nM。 | |||
T25061 | Altromycin A | ||
Altromycin A is an anticancer agent. | |||
T69773 | Emzeltrectinib | ||
Emzeltrectinib 是一种有效的酪氨酸激酶抑制剂,具有抗肿瘤活性。 | |||
T71289 | 9-O-Demethyltrigonostemone | ||
9-O-Demethyltrigonostemone is a natural IDO1 inhibitor, cytotoxic and antiplasmodial agent from the Roots of Strophioblachia fimbricalyx. | |||
T40845 |
Methylnaltrexone iodide
Naltrexonium methiodide,碘化甲基纳曲酮; 碘甲纳曲酮 |
||
Methylnaltrexone iodide, a quaternary derivative of Naltrexone, is an orally active and selective antagonist of the mu-opioid receptor. It acts peripherally in the gastrointestinal tract to antagonize the receptor. Furthermore, Methylnaltrexone iodide exhibits limited permeability across the blood-brain barrier. | |||
T125220 |
Cyclo[N1'-(1,1-dimethyl-2-propenyl)tryptophyltrypt
|
||
Cyclo[N1'-(1,1-dimethyl-2-propenyl)tryptophyltrypt 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125220,CAS号为 244066-05-5。 | |||
T33323 |
Methionyltryptophan
Met-trp,Methionyl-tryptophan,Methionyl tryptophan |
||
Methionyl-Tryptophan is a dipeptide composed of methionine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. | |||
T70175 |
Fadaltran
|
||
Fadaltran is an α2-adrenoreceptor antagonist. | |||
T31256 |
Deacetyltrimepranol
Desacetylmetipranolol |
||
Deacetyltrimepranol also known as Desacetylmetipranolol, is the active metabolite of metipranolol. | |||
T25063 |
Altromycin C
|
||
Altromycin C is a new pluramycin-like antibiotic. | |||
T31798 |
Flavinyltryptophan
|
||
Flavinyltryptophan is a flavinyl peptide. | |||
T31438 |
Didecanoyltriethylene glycol ester
Triethylene glycol dicaprate |
||
Didecanoyltriethylene glycol ester is a biochemical. | |||
T20885 | Acetyltriethyl citrate | ||
Acetyltriethyl citrate is a biochemical. | |||
T20542 | Chloroacetyltryptophan | ||
Chloroacetyltryptophan is a bioactive chemical substance. | |||
T29920 | Altropane | ||
Altropane is a SPECT imaging agent used for viewing dopamine transporter sites. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0200 |
α-Lipoic Acid
Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid,α-硫辛酸,硫辛酸 |
Apoptosis; NF-κB; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite | Apoptosis; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
α-Lipoic Acid (DL-α-Lipoic acid) 是线粒体酶复合物的重要辅助因子,是一种抗氧化剂,可抑制NF-κB 依赖性的HIV-1LTR 活化。它还可诱导内质网应激介导的肝癌细胞凋亡。 | |||
TJP2872 |
Acevaltrate
Acevaltratum,乙酰缬草三酯,Acetoxyvaltrate |
ATPase; Others | Membrane transporter/Ion channel; Others |
Acevaltrate (Acevaltratum) 对人小细胞肺癌细胞系 GLC(4) 和人结肠直肠癌细胞系 COLO 320 具有高细胞毒性,IC50 值为 1-6 uM。它抑制大鼠肾和脑半球中 Na+/K+-ATP 酶活性,IC50分别为 22.8 和 42.3 μM。 | |||
TN7080 |
D-altrofurano-heptulose-3
alpha-D-Altro-3-heptulofuranose,D-阿卓-呋喃庚酮糖 |
Others | Others |
D-altrofurano-heptulose-3 (alpha-D-Altro-3-heptulofuranose) 从猕猴桃 (Rupr. & Maxim.) Maxim., 猕猴桃科的根茎中分离得到。 | |||
TN3844 |
Didrovaltrate
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Didrovaltrate shows cytotoxic against human cancer cell lines. Didrovaltrate blocks I(Ca-L) in a concentration-dependent manner and probably inhibits I(Ca-L) in its inactive state, which may contribute to its cardiovascular effect. | |||
TN3646 |
Chlorovaltrate K
|
Others | Others |
Chlorovaltrate K shows moderate cytotoxicity against lung adenocarcinoma (A 549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8) and hepatoma (Bel 7402) cell lines with IC50 values of 0.89-9.76 uM. | |||
TN6571 |
Nb-Feruloyltryptamine
|
||
Nb-Feruloyltryptamine 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6571,CAS号为 53905-13-8。 | |||
TN4352 |
Jatamanvaltrate B
|
Others | Others |
Jatamanvaltrate B shows cytotoxicity against lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8),and hepatoma (Bel7402) cell lines. | |||
TN5249 |
Volvaltrate B
|
Others | Others |
Volvaltrate B shows cytotoxic activity against the lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8), and hepatoma (Bel7402) cell lines, with IC50 values of 8.5, 2.0, 3.2, and 6.1 uM, respectively. | |||
TN4341 |
IVHD-valtrate
|
Mdm2; BCL; PARP; Caspase; p53 | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome |
VHD-valtrate has anticancer effects against human ovarian cancer cells in vitro and in vivo, it is a potential therapeutic agent for ovarian cancer, providing a basis for development of the compound as a novel chemotherapeutic agent. | |||
TN5428 |
4-Demethyltraxillaside
5'-Methoxymatairesinoside,5'-甲氧基罗汉松脂苷 |
||
4-Demethyltraxillaside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5428,CAS号为 1691201-82-7。 | |||
T8803 | Valtrate hydrine B4 | ||
Valtrate hydrine B4 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T8803,CAS号为 18296-48-5。 | |||
T81225 |
Salicyloyltremuloidin
|
||
Salicyloyltremuloidin为从木瓜柳(Salix chaenomeloides)叶中分离得到的葡萄糖苷。 | |||
T2930 |
α-Lipoic Acid
Lipoic acid,Alphalipoic acid,硫辛酸 |
NF-κB; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite | Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome |
α-Lipoic Acid (Alphalipoic acid) 抑制 NF-κB 依赖性 HIV-1 LTR 活化。 α-硫辛酸诱导内质网 (ER) 应激介导的肝癌细胞凋亡。α-硫辛酸是一种抗氧化剂,是线粒体酶复合物的重要辅助因子。 | |||
TN5880 |
Mesuol
|
||
Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and phagocytosis in carbon clearance assay. Mesuol can suppress HIV-1 replication in Jurkat T cells, it inhibits TNFα-induced HIV-1-LTR transcriptional activity by targeting the nuclear factor-κB (NF-κB) pathway. | |||
T72429 |
α-Lipoic Acid sodium
Thioctic acid sodium,DL-α-Lipoic acid sodium,Thioctic acid sodium ; (±)-α-Lipoic acid sodium ; DL-α-Lipoic acid sodium,(±)-α-Lipoic acid sodium |
||
α-Lipoic Acid (Thioctic acid) sodium 是一种抗氧化剂,是线粒体酶复合物的重要辅助因子。α-Lipoic Acid sodium 可抑制NF-κB 依赖性的HIV-1LTR 活化。α-Lipoic Acid sodium 诱导内质网应激 (ERS) 介导的肝癌细胞凋亡 (apoptosis)。α-Lipoic Acid sodium 可与CPUL1 合成自组装的纳米聚合体 CPUL1-LA NA,其抗肿瘤效果优于 CPUL1。 |