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Search Results for " def "

Targets Recommended: Others

48

抑制剂 & 化合物

1

天然产物

34

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP2157L	TAT-DEF-Elk-1 TFA (1220751-16-5 free base) TDE TFA,TAT-DEF-Elk-1 TFA	Others	Others
	TAT-DEF-Elk-1 TFA is a cell-penetrating peptide Elk-1 inhibitor, mimics and specifically interferes with the DEF domain of Elk-1. TAT-DEF-Elk-1 blocks Elk-1 phosphorylation and prevents Elk-1 nuclear translocation without interfering with ERK nor MSK1 act
TP2157	TAT-DEF-Elk-1 TDE	Others	Others
	TAT-DEF-Elk-1 is a cell-penetrating peptide Elk-1 inhibitor.
T81038	TAT-DEF-Elk-1 TFA TDE TFA
	TAT-DEF-Elk-1 TFA (TDE TFA) 是一种Elk-1的细胞穿透性肽抑制剂，通过模仿Elk-1的DEF域并特异性地阻断其功能来抑制Elk-1。该化合物能够抑制Elk-1的磷酸化作用，阻止其核内转位，同时不影响ERK和MSK1的活化。TAT-DEF-Elk-1 TFA作为一种研究工具，对于探究神经元可塑性及Elk-1在该进程中的角色具有重要价值。
T19692	Deferitrin GT 56252,GT 56 252,地夫立群,GT-56252,GT-56-252	Others	Others
	Deferitrin (GT-56-252) 是一种具有口服活性的三叉戟铁螯合剂，是去铁硫素 (DFT) 类似物。它有用于严重的 β 地中海贫血的潜力。它用于输血引起的慢性铁超负荷。
T31362	Deferitazole SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602	Others	Others
	Deferitazole (FBS 0701) 是一种新型且具有口服活性、选择性和高亲和力的铁螯合剂。
T1565	Deferiprone 去铁酮,Deferidone,CP20	Others; HCV Protease; Ferroptosis; UGT	Apoptosis; Metabolism; Microbiology/Virology; Others; Proteases/Proteasome
	Deferiprone (Deferidone) 是口服活性铁螯合剂，可研究地中海贫血中的输血性铁过载。
T124358	Deferoxamine Deferoxamine B,Desferrioxamine B	Apoptosis; Antioxidant; HIF; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; oxidation-reduction
	Deferoxamine（Desferrioxamine B）是一种铁螯合剂 (结合 Fe(III) 和许多其他金属阳离子)，可抑制神经元病变，可用于改减少铁在组织中的积累和沉积，可通过抑制创伤性脑损伤后的铁死亡和神经炎症来改善神经功能障碍。Desferrioxamin-B 具有抗氧化、抗增殖、抗肿瘤活性，可诱导 HIF-1α 产生，诱导癌细胞凋亡和自噬。Desferrioxamin-B 可用于治疗急性铁中毒和与 COVID-19 相关疾病。
T1675	Adefovir dipivoxil Hepsera,GS 0840,阿德福韦酯,Preveon	Others; HBV; Reverse Transcriptase	Microbiology/Virology; Others
	Adefovir dipivoxil (GS 0840) 是一种腺苷类似物，是核苷逆转录酶抑制剂 Adefovir 的口服前药，具有抗乙型肝炎病毒、疱疹病毒和人类免疫缺陷病毒的活性。
T19526	Pradefovir mesylate Pradefovir mesilate,Remofovir mesylate,Hepavir B,甲磺酸帕拉德福韦	P450	Metabolism
	Pradefovir mesylate (Hepavir B) 是一种肝脏 CYP3A4 底物。在人肝微粒体中，Pradefovir 能够转化为 9-[2-(磷酸甲氧基)乙基]腺嘌呤，其Km=60 μM。
T29328	21-deacetyldeflazacort	Others	Others
	21-deacetyldeflazacort 是 Deflazacort 的代谢物，它是一种全身性皮质类固醇和泼尼松龙的衍生物。
T13639	Deferasirox (Fe3+ chelate)	Apoptosis	Apoptosis
	Deferasirox (Fe3+ chelate) 是一种可口服的铁螯合剂，具有潜在的抗癌活性，抑制 MCL-1 的抗凋亡活性，可用于研究铁超负荷。
T1457	Deferasirox ICL 670,CGP-72670,地拉罗司	Others; Ferroptosis; Antibacterial	Apoptosis; Microbiology/Virology; Others
	Deferasirox (CGP-72670) 是一种口服铁螯合剂，用于治疗慢性铁过载。
T7447	Adefovir	HBV; Reverse Transcriptase; Telomerase	DNA Damage/DNA Repair; Microbiology/Virology
	Adefovir 是一种单磷酸腺苷类似物抗病毒剂，在细胞内转化为 Adefovir diphosphate 后可抑制HBVDNA 聚合酶。它在 HepG2.2.15 细胞系中对HBV 的IC50为 0.7 μM。它对多种病毒(包括HBV 和疱疹病毒)具有良好的抗病毒活性。
T24661	Pridefine Pridefina
	Pridefine is an antidepressant drug. It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine. It also has some weak releasing activity.
T6552	Istradefylline 伊曲茶碱,KW-6002	Adenosine Receptor	GPCR/G Protein; Neuroscience
	Istradefylline (KW-6002) 是选择性的可口服的腺苷 A2A 受体拮抗剂，可用于研究药物滥用、睡眠障碍、肝损伤、帕金森病和不安腿综合征等的治疗和基础科学的试验。
T1996	Defactinib PF-04554878,VS-6063	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Defactinib (VS-6063) 是新型的 FAK 抑制剂，能够时间和剂量依赖性的抑制 FAK 在 Tyr397 位点磷酸化。
T1637	Deferoxamine Mesylate desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM,去铁铵,甲磺酸去铁胺	Mitophagy; Beta Amyloid; Others; Ferroptosis; HIF/HIF Prolyl-Hydroxylase; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Metabolism; Neuroscience; Others
	Deferoxamine Mesylate (DFOM) 是一种铁螯合剂和铁死亡抑制剂。Deferoxamine Mesylate 可将游离铁结合成稳定的复合物，减少铁的积累。Deferoxamine Mesylate 可以上调 HIF-1α 水平，诱导细胞凋亡。
T76070	Defensin HNP-1 human TFA
	Defensin HNP-1 human TFA，一种人中性粒细胞肽(HNPs)，在早期动脉粥样硬化发展中涉及内皮细胞功能障碍。该化合物展现出广泛的抗菌及抗利什曼原虫活性。
T38103	Defensin HNP-3 (human) (trifluoroacetate salt)
	Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd...
T80375	Human α-defensin 5	Parasite	Microbiology/Virology
	Human α-defensin 5 是抗病毒肽，能够阻断多种无包膜病毒感染，如AdV、HPV以及多瘤病毒（IC50: HPV16为0.6-1.25 μM）。它通过与病毒衣壳结合来阻止病毒从内体逃逸，并能增强HIV与细胞表面的结合作用。此外，Human α-defensin 5 还具备对抗寄生虫的活性。
T41134	Defensin HNP-2 human
	Defensin HNP-2 is a naturally occurring antibiotic and monocyte chemotactic peptide synthesized by human neutrophils.
T34741	Sulfidefluor-7 AM SF7-AM
	Sulfidefluor-7 AM (SF7-AM) 是一种有效的和具有细胞渗透性的硫化氢(h2s)荧光探针。Sulfidefluor-7 AM 含有乙酰氧基甲酯，在细胞内水解以捕获探针。
T76501	Defensin HNP 4
	Defensin HNP 4，一种由11个氨基酸组成的HNP-41-11的片段，对多药耐药及非耐药菌株均显示出抑制效果。
T76063L	Beta-defensin 1, pig TFA
	Beta-defensin 1, pig TFA 是一种在猪舌黏膜中主要发现的抗菌肽，对多种细菌如大肠杆菌、鼠伤寒沙门氏菌、单核细胞增生性李斯特菌、金黄色葡萄球菌、百日咳博德特氏菌和白色念珠菌等显示出抗菌活性。
T28449	Pradefovir ICN-2001-3,MB-6866,帕拉德福韦,ICN-20013,MB-06866,Remofovir	HBV	Microbiology/Virology
	Pradefovir (Remofovir) 是一种逆转录酶抑制剂，可能用于治疗慢性 HBV 感染。它也是阿德福韦的肝脏靶向前药。代谢激活后，它在人肝微粒体中转化为 PMEA(9-(2-膦酰基甲氧基乙基)腺嘌呤)，Km 为 60 microM，最大代谢速率为 228 pmol/min/mg 蛋白质，以及内在的清除率约为 359 ml/min。
T25219	Cedefingol SPC-101210,SP101210,SPC 101210
	Cedefingol is an antineoplastic agent.
T40470	Human β-defensin-2 Human β-defensin-2,HβD-2
	Human β-defensin-2 (HβD-2) is a cationic skin-antimicrobial peptide (SAP) characterized by its small size and rich cysteine content. It is produced by various epithelial cells and exhibits potent antimicrobial properties against gram-negative bacteria and Candida. However, it does not effectively target gram-positive Staphylococcus aureus. Given these characteristics, Human β-defensin-2 serves as a valuable tool in colitis research.
T31363	Deferitazole magnesium FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base
	Deferitazole magnesium is a potential chelator for iron overload treatment.
T76064	Beta-defensin 103 isoform X1, pig
	Beta-defensin 103 isoform X1, pig 是一种抗菌肽、在多种生物体内被发现，参与了先天性免疫防线。
T35451	β-Defensin-2 (human) (trifluoroacetate salt)
	β-Defensin-2 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius.2β-Defensin-2 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes.3It also stimulates calcium mobilization, migration, and proliferation of keratinocytes whe...
T76503	Defensin NP-3A
	Defensin NP-3A (NP-3A; Corticostatin 1) 是一种人粒细胞肽，具有抗 ACTH 活性。防御素是一种具有杀伤活性的抗菌肽。
T35452	β-Defensin-3 (human) (trifluoroacetate salt)
	β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It inhibits the growth of the periodontopathogenic and cariogenic bacteria F. nucleatum, S. mutans, S. sobrinus, S. salivarius, and L. casei (MICs = 12.5-100 mg/l). It also inhibits the growth of S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. β-Defensin-3 stimulates gene expression and production of IL-6, IL-10, CXC...
T71036	Adefovir monophosphate
	Adefovir monophosphate is an antiviral acyclic nucleoside phosphonate (ANP) analog with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV). It is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) that works by blocking reverse transcriptase for the treatment of hepatitis B. Adefovir dipivoxil is not effective against HIV-1.
T81502	Pezadeftide	Antibiotic	Microbiology/Virology
	Pezadeftide为一种抗真菌肽，能够穿透真菌细胞并迅速诱发线粒体反应，进而引起线粒体膜超极化。
T80362	Human α-Defensin 6
	Human α-Defensin 6，含32个半胱氨酸残基的抗菌肽，能够阻止细菌入侵，促进粘膜免疫。该肽通过自组装形成有序的原纤维和纳米网，能随机结合细菌表面蛋白，进而围绕并缠绕细菌。此外，Human α-Defensin 6抑制C. albicans生物膜的形成。
TMIH-0178	Deferasirox-d4
	Deferasirox-d4 是 Deferasirox 的氘代化合物。
T15092	Defactinib hydrochloride VS-6063 hydrochloride,PF 04554878 hydrochloride	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Defactinib hydrochloride (PF 04554878 hydrochloride) (VS-6063 hydrochloride; PF 04554878 hydrochloride) 是一种新型 FAK 抑制剂，抑制 FAK 在 Tyr397 位点磷酸化，这种作用具有时间和剂量依赖性。
T80045	Defensin HNP-3 human	Antibiotic	Microbiology/Virology
	Defensin HNP-3 human 是一种具有抑制金黄色葡萄球菌、铜绿假单胞菌和大肠杆菌活性的细胞毒性抗生素肽。该肽原先以94个氨基酸的preproHNP(1-94)形式合成，随后水解为proHNP(20-94)，最终通过去除阴离子前体转化为成熟形式的HNP(65-94)。
T76064L	Beta-defensin 103 isoform X1, pig TFA
	Beta-defensin 103 isoform X1, pig TFA 是一种抗菌肽、在多种生物体内被发现，参与了先天性免疫防线。
T80323	Bovine neutrophil beta-defensin 12 BNBD-12
	Bovine neutrophil beta-defensin 12，一种牛中性粒细胞来源的抗菌肽，展现针对大肠杆菌(Escherichia coli)和金黄色葡萄球菌(Staphylococcus aureus)的抗菌活性。
T40550	Human β-defensin-1 Human β-defensin-1,HβD-1
	Human β-defensin-1 (HβD-1) is a cysteine-rich cationic skin-antimicrobial peptide (SAP) produced by epithelial surfaces, circulatory cells, and cells of the reproductive tract. It exhibits antimicrobial activity against a wide range of sperm bacteria.
T39683	Human β-defensin-3 Human β-defensin-3,HβD-3
	Human β-defensin-3 (HβD-3) is an antibiotic antimicrobial peptide synthesized by epithelial cells. It exhibits potent antimicrobial properties and mitigates inflammatory cytokine responses. HβD-3 efficiently targets various microorganisms, displaying IC90 values ranging from 6 to 25 μg/ml.
T35426	β-Defensin-1 (human) (trifluoroacetate salt)
	β-Defensin-1 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts.1It inhibits the growth ofB. adolescentis,L. acidophilus,B. breve,B. vulgatus,L. fermentum,B. longum, andS. thermophilusin an antimicrobial radial diffusion assay.2β-Defensin-1 also inhibits the growth of periodontopathogenic and cariogenic bacteria, includingP. gingivalisandS. salivarius, and of susceptibleM. tuberculosisH37Rv but no...
T76063	Beta-defensin 1, pig
	Beta-defensin 1, pig 是一种在猪舌黏膜中主要发现的抗菌肽，对包括大肠杆菌、鼠伤寒沙门氏菌、单核细胞增生性李斯特菌、金黄色葡萄球菌、百日咳博德特氏菌和白色念珠菌在内的多种细菌显示出活性。
T41135	Defensin HNP-1 human
	Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development.Defensin HNP-1 human can regulate the growth of atherosclerosis.
T10139	4-Desmethyl Istradefylline	Others	Others
	4-Desmethyl Istradefylline is a Istradefylline metabolite. Istradefylline is a very potent, selective, and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
T81652	Nordefrin (±)-Cobefri
	Nordefrin ((±)-Cobefri)为Norepinephrine的衍生物，具有血管收缩作用。
T35453	β-Defensin-4 (human) (trifluoroacetate salt)
	β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at a concentration of 10 nM but does not affect migration of neutrophils and eosinophils. β-Defensin-4 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes. It also stimulates calcium mobilization, migration, and pro...

化合物

TAT-DEF-Elk-1 TFA (1220751-16-5 free base)

Cat.No: TP2157L

Synonym: TDE TFA,TAT-DEF-Elk-1 TFA

Target: Others

TAT-DEF-Elk-1

Cat.No: TP2157

Synonym: TDE

Target: Others

TAT-DEF-Elk-1 TFA

Cat.No: T81038

Synonym: TDE TFA

Cat.No: T19692

Synonym: GT 56252,GT 56 252,地夫立群,GT-56252,GT-56-252

Target: Others

Cat.No: T31362

Synonym: SPD602,FBS 0701,SPD-602,FBS0701,FBS-0701,SPD 602

Target: Others

Cat.No: T1565

Synonym: 去铁酮,Deferidone,CP20

Target: Others, HCV Protease, Ferroptosis, UGT

Cat.No: T124358

Synonym: Deferoxamine B,Desferrioxamine B

Target: Apoptosis, Antioxidant, HIF, Autophagy

Adefovir dipivoxil

Cat.No: T1675

Synonym: Hepsera,GS 0840,阿德福韦酯,Preveon

Target: Others, HBV, Reverse Transcriptase

Pradefovir mesylate

Cat.No: T19526

Synonym: Pradefovir mesilate,Remofovir mesylate,Hepavir B,甲磺酸帕拉德福韦

Target: P450

21-deacetyldeflazacort

Cat.No: T29328

Target: Others

Deferasirox (Fe3+ chelate)

Cat.No: T13639

Target: Apoptosis

Cat.No: T1457

Synonym: ICL 670,CGP-72670,地拉罗司

Target: Others, Ferroptosis, Antibacterial

Cat.No: T7447

Target: HBV, Reverse Transcriptase, Telomerase

Cat.No: T24661

Synonym: Pridefina

Cat.No: T6552

Synonym: 伊曲茶碱,KW-6002

Target: Adenosine Receptor

Cat.No: T1996

Synonym: PF-04554878,VS-6063

Target: FAK

Deferoxamine Mesylate

Cat.No: T1637

Synonym: desferrioxamine B,Desferrioxamine B mesylate,DFO,DFOM,去铁铵,甲磺酸去铁胺

Target: Mitophagy, Beta Amyloid, Others, Ferroptosis, HIF/HIF Prolyl-Hydroxylase, Autophagy

Defensin HNP-1 human TFA

Cat.No: T76070

Defensin HNP-3 (human) (trifluoroacetate salt)

Cat.No: T38103

Human α-defensin 5

Cat.No: T80375

Target: Parasite

Defensin HNP-2 human

Cat.No: T41134

Sulfidefluor-7 AM

Cat.No: T34741

Synonym: SF7-AM

Defensin HNP 4

Cat.No: T76501

Beta-defensin 1, pig TFA

Cat.No: T76063L

Cat.No: T28449

Synonym: ICN-2001-3,MB-6866,帕拉德福韦,ICN-20013,MB-06866,Remofovir

Target: HBV

Cat.No: T25219

Synonym: SPC-101210,SP101210,SPC 101210

Human β-defensin-2

Cat.No: T40470

Synonym: Human β-defensin-2,HβD-2

Deferitazole magnesium

Cat.No: T31363

Synonym: FBS0701,FBS-0701,SSP-004184,SHP-602,SHP602,Deferitazole free base

Beta-defensin 103 isoform X1, pig

Cat.No: T76064

β-Defensin-2 (human) (trifluoroacetate salt)

Cat.No: T35451

Defensin NP-3A

Cat.No: T76503

β-Defensin-3 (human) (trifluoroacetate salt)

Cat.No: T35452

Adefovir monophosphate

Cat.No: T71036

Cat.No: T81502

Target: Antibiotic

Human α-Defensin 6

Cat.No: T80362

Deferasirox-d4

Cat.No: TMIH-0178

Defactinib hydrochloride

Cat.No: T15092

Synonym: VS-6063 hydrochloride,PF 04554878 hydrochloride

Target: FAK

Defensin HNP-3 human

Cat.No: T80045

Target: Antibiotic

Beta-defensin 103 isoform X1, pig TFA

Cat.No: T76064L

Bovine neutrophil beta-defensin 12

Cat.No: T80323

Synonym: BNBD-12

Human β-defensin-1

Cat.No: T40550

Synonym: Human β-defensin-1,HβD-1

Human β-defensin-3

Cat.No: T39683

Synonym: Human β-defensin-3,HβD-3

β-Defensin-1 (human) (trifluoroacetate salt)

Cat.No: T35426

Beta-defensin 1, pig

Cat.No: T76063

Defensin HNP-1 human

Cat.No: T41135

4-Desmethyl Istradefylline

Cat.No: T10139

Target: Others

Cat.No: T81652

Synonym: (±)-Cobefri

β-Defensin-4 (human) (trifluoroacetate salt)

Cat.No: T35453

Cat. No.	Product Name	Target	Signaling Pathways
T80344	Aeschna defensin
	Aeschna defensing是源自蜻蜓水生幼虫血淋巴的抗菌肽，对革兰氏阳性菌具有显著活性。

天然产物

Aeschna defensin

Cat.No: T80344

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc) HMG-1,SBP-1,high mobility group box 1,p30,Hmg1,DEF,...	Mouse	HEK293 Cells
	HMGB1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.3 kDa and the accession number is P63158.
TMPY-00542	DEFB127 Protein, Human, Recombinant (hFc) DEFB127,defensin beta 127,bA530N10.2,D...	Human	HEK293 Cells
	DEFB127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 31.8 kDa and the accession number is A0A2J8MRU9.
TMPY-00346	DEFA3 Protein, Human, Recombinant (hFc) Defensin α3/DEFA3,defensin alpha ...	Human	HEK293 Cells
	DEFA3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.8 kDa and the accession number is P59666.
TMPY-02835	DEFB103A Protein, Human, Recombinant (His) DEFB3,HBP3,defensin, beta 103A,hBD-3,D...	Human	E. coli
	Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kid...
TMPH-02503	DEFA1 Protein, Mouse, Recombinant (GST & His) HP-1,HNP-1,Defensin, alpha 1,DEFA1,DEF...	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. Has antibacterial activity against attenuated mutants of S.typhimurium. DEFA1 Protein, Mouse, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 34.1 kDa and the accession number is P11477.
TMPH-03566	Peptide deformylase Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is P68826.
TMPH-00460	Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) DmAMP1,Defensin-like protein 1,Cysteine-rich antimi...	Dahlia merckii	E. coli
	Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) is expressed in E. coli.
TMPH-03101	DEFB1 Protein, Pig, Recombinant (GST) DEFB1,Defensin, beta 1,Beta-defen...	Sus scrofa (Pig)	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. DEFB1 Protein, Pig, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is O62697.
TMPH-01005	DEFB128 Protein, Human, Recombinant (His & Myc) DEFB-28,Beta-defensin 128,DEFB28,...	Human	E. coli
	Has antibacterial activity. DEFB128 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 16.0 kDa and the accession number is Q7Z7B8.
TMPJ-00667	DEFB4A Protein, Human, Recombinant DEFB4,DEFB4A,hBD-2,Beta-Defensin ...	Human	E. coli
	β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expre...
TMPH-03148	DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) Defensin, beta 126,DEFB126,Beta-def	Pongo pygmaeus	P. pastoris (Yeast)
	DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 31.9 kDa and the accession number is A4H244.
TMPH-02543	DEFB33 Protein, Mouse, Recombinant (His & Myc & SUMO) BD-33,Defb33,mBD-33,Defensin, beta 33,Beta...	Mouse	E. coli
	Has antibacterial activity.
TMPH-03509	Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO)	SIV	E. coli
	Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 28.9 kDa and the accession number is P19508.
TMPH-01772	DEFA1 Protein, Human, Recombinant (GST) MRS,HP1,HP-1,DEFA1,DEF1,Defensin,...	Human	E. coli
	Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. DEFA1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 37.2 kDa and the accession number is P59665.
TMPH-02541	Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO) Beta-defensin 1,BD-1,mBD-1,Defensin, beta ...	Mouse	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
TMPH-00679	Peptide deformylase Protein, E. coli O157:H7, Recombinant (His)	E. coli	P. pastoris (Yeast)
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
TMPY-04170	DEFB1 Protein, Human, Recombinant (hFc) DEFB101,defensin, β1,β Defensin 1...	Human	HEK293 Cells
	The DEFB1 gene, encoding for the constitutively expressed human beta-defensin 1 (hBD1) antimicrobial peptide is a potential candidate when studying genetic susceptibility to caries. DEFB1 genetic variations have been reported as contributing to hBD1 production impairment, leading to a greater susceptibility to be infected by oral pathogens, also leading to periodontitis. To counteract host immunity, Cryptosporidium parvum has evolved multiple strategies to suppress host antimicrobial defense. On...
TMPY-01115	DEFB119 Protein, Human, Recombinant (mFc) DEFB-20,DEFB120,DEFB19,ESC42-RELB...	Human	HEK293 Cells
	DEFB119 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8N690-1.
TMPJ-01243	DEFB4 Protein, Human, Recombinant DEFB4,DEFB104B,hBD-4,DEFB104,BD-4...	Human	E. coli
	Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursor...
TMPJ-00003	DEFB1 Protein, Human, Recombinant Beta-Defensin 1,BD-1,HBD1,Defensin β1,BD1,...	Human	E. coli
	β-Defensin 1 (DEFB1) is a member of the β-defensin family, which is highly expressed by epithelial cells. β-defensins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal peptide. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. β-defensin 1 is an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. Defects in β-Defensin-1 contribute to asthma diagnosis,...
TMPH-02542	DEFB19 Protein, Mouse, Recombinant (His & Myc) Defensin, beta 19,Tdl,Testis-specific beta-def<...	Mouse	E. coli
	Has antibacterial activity.
TMPH-00678	Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO)	E. coli	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P0A6K5.
TMPY-00336	Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His) SIV-GP12	SIV	HEK293 Cells
	Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is E2EXP2.
TMPH-03567	Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is P68826.
TMPH-02504	DEFA5 Protein, Mouse, Recombinant (GST) Defa5,Alpha-defensin 5,Defensin-r...	Mouse	E. coli
	Probably contributes to the antimicrobial barrier function of the small bowel mucosa. DEFA5 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.2 kDa and the accession number is P28312.
TMPH-02545	DEFB6 Protein, Mouse, Recombinant (His & KSI) Defb6,Beta-defensin 6,Defensin, b...	Mouse	E. coli
	Has potent antibacterial activity against E.coli (ATCC 25922). DEFB6 Protein, Mouse, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 19.8 kDa and the accession number is Q91VD6.
TMPY-00331	Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His) SIV-GP12	SIV	HEK293 Cells
	Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is D7PU90.
TMPH-01006	DEFB129 Protein, Human, Recombinant (His & Myc) DEFB129,C20orf87,Beta-defensin 129,DEF...	Human	P. pastoris (Yeast)
	Has antibacterial activity. DEFB129 Protein, Human, Recombinant (His & Myc) is expressed in yeast with C-6xHis-Myc tag. The predicted molecular weight is 21.8 kDa and the accession number is Q9H1M3.
TMPH-00061	Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI)	Apis mellifera carnica	E. coli
	Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration. Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.9 kDa and the accession number is Q5J8R1.
TMPH-03082	DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI) BD-6,cBD-6,DEFB6,DEFB106,DEFB106A...	Chimpanzee	E. coli
	Has antibacterial activity. Acts as a ligand for C-C chemokine receptor CCR2. DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.4 kDa and the accession number is Q5IAB3.
TMPH-00063	Defensin-1 Protein, Apis mellifera, Recombinant (His)	Apis mellifera	E. coli
	Found in royal jelly and in hemolymph, potent antibacterial protein against Gram-positive bacteria at low concentration. Defensin-1 Protein, Apis mellifera, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 11.6 kDa and the accession number is P17722.
TMPY-00328	Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His) SIV-GP12	SIV	HEK293 Cells
	Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.8 kDa and the accession number is P12492.
TMPH-00702	Peptide deformylase Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P0A6K3.
TMPH-02544	DEFB4 Protein, Mouse, Recombinant (His & SUMO) Bdef4,BD-4,Beta-defensin 4,Defens...	Mouse	E. coli
	Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. DEFB4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 20.6 kDa and the accession number is P82019.

重组蛋白

HMGB1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02590

Species: Mouse

Expression System: HEK293 Cells

DEFB127 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00542

Species: Human

Expression System: HEK293 Cells

DEFA3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00346

Species: Human

Expression System: HEK293 Cells

DEFB103A Protein, Human, Recombinant (His)

Cat.No: TMPY-02835

Species: Human

Expression System: E. coli

DEFA1 Protein, Mouse, Recombinant (GST & His)

Cat.No: TMPH-02503

Species: Mouse

Expression System: E. coli

Peptide deformylase Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03566

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His)

Cat.No: TMPH-00460

Species: Dahlia merckii

Expression System: E. coli

DEFB1 Protein, Pig, Recombinant (GST)

Cat.No: TMPH-03101

Species: Sus scrofa (Pig)

Expression System: E. coli

DEFB128 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01005

Species: Human

Expression System: E. coli

DEFB4A Protein, Human, Recombinant

Cat.No: TMPJ-00667

Species: Human

Expression System: E. coli

DEFB126 Protein, Pongo pygmaeus, Recombinant (GST)

Cat.No: TMPH-03148

Species: Pongo pygmaeus

Expression System: P. pastoris (Yeast)

DEFB33 Protein, Mouse, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-02543

Species: Mouse

Expression System: E. coli

Simian immunodeficiency virus (SIV) (isolate PBj14/BCL-3) Vpx Protein (His & SUMO)

Cat.No: TMPH-03509

Species: SIV

Expression System: E. coli

DEFA1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01772

Species: Human

Expression System: E. coli

Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02541

Species: Mouse

Expression System: E. coli

Peptide deformylase Protein, E. coli O157:H7, Recombinant (His)

Cat.No: TMPH-00679

Species: E. coli

Expression System: P. pastoris (Yeast)

DEFB1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-04170

Species: Human

Expression System: HEK293 Cells

DEFB119 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-01115

Species: Human

Expression System: HEK293 Cells

DEFB4 Protein, Human, Recombinant

Cat.No: TMPJ-01243

Species: Human

Expression System: E. coli

DEFB1 Protein, Human, Recombinant

Cat.No: TMPJ-00003

Species: Human

Expression System: E. coli

DEFB19 Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02542

Species: Mouse

Expression System: E. coli

Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO)

Cat.No: TMPH-00678

Species: E. coli

Expression System: E. coli

Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His)

Cat.No: TMPY-00336

Species: SIV

Expression System: HEK293 Cells

Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03567

Species: Staphylococcus aureus

Expression System: E. coli

DEFA5 Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02504

Species: Mouse

Expression System: E. coli

DEFB6 Protein, Mouse, Recombinant (His & KSI)

Cat.No: TMPH-02545

Species: Mouse

Expression System: E. coli

Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His)

Cat.No: TMPY-00331

Species: SIV

Expression System: HEK293 Cells

DEFB129 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01006

Species: Human

Expression System: P. pastoris (Yeast)

Defensin-1 Protein, Apis mellifera carnica, Recombinant (His & KSI)

Cat.No: TMPH-00061

Species: Apis mellifera carnica

Expression System: E. coli

DEFB106A Protein, Pan troglodytes, Recombinant (His & KSI)

Cat.No: TMPH-03082

Species: Chimpanzee

Expression System: E. coli

Defensin-1 Protein, Apis mellifera, Recombinant (His)

Cat.No: TMPH-00063

Species: Apis mellifera

Expression System: E. coli

Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His)

Cat.No: TMPY-00328

Species: SIV

Expression System: HEK293 Cells

Peptide deformylase Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00702

Species: E. coli

Expression System: E. coli

DEFB4 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02544

Species: Mouse

Expression System: E. coli

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