39
22
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17117 |
Tonapofylline
BG 9928 |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Tonapofylline 是一种具有口服活性的选择性 A1 腺苷受体拮抗剂(Ki:7.4 nM,对人 A1)。 Tonapofylline 可用于有关心力衰竭的研究。 | |||
T2294 |
BG45
|
Apoptosis; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
BG45是一个 HDAC I 型抑制剂,选择性抑制 HDAC3,IC50为289 nM。它抑制 HDAC1/2/6的效力大大降低,IC50分别为2、2.2和>20μM。 | |||
T40322 |
BG dimer
|
||
BG dimer is a molecular dimer organic luminogen with aggregation-induced emission. | |||
T5519 |
Bivalirudin
BG-8967,比伐卢定,Hirulog-1 |
Thrombin | Proteases/Proteasome |
Bivalirudin (BG-8967) 是一种直接凝血酶(thrombin)抑制剂,是一种肽类抗凝剂,可在侵入性心脏病,特别是在经皮冠状动脉介入中用于抗凝。 | |||
T19841 |
Tribenoside
Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,三苄糖苷,TBGF |
Others | Others |
Tribenoside (BG-356) 是血管保护剂,能够温和的镇痛、抗炎及伤口愈合,可用研究痔疮。 | |||
T26786 |
BG14
BG 14,BG-14 |
||
BG14 is a probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases using visible light. | |||
T26787 |
BG47
BG-47,BG 47 |
||
BG47 is a probe for chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases using visible light. | |||
T26788 |
BG48
BG-48,BG 48 |
||
BG48 is a probe of chemo-optical modulation of epigenetically regulated transcription (COMET). It enables high-resolution, optical control of epigenetic mechanisms and photochromically inhibits human histone deacetylases using visible light. | |||
T27545 |
Hirugen
BG 8865,Hirudin dodecapeptide |
||
Hirugen is a derivative of hirudin, which is an anticoagulant protein found in leeches. | |||
T78303 |
Baminercept
TT-47,BG 9924 |
||
Baminercept (BG 9924)为一种LTβR-Ig淋巴毒素β受体IgG融合蛋白,用于多种自身免疫疾病研究,包括原发性干燥综合征(SS)与类风湿性关节炎(RA)。 | |||
T26565 |
Adentri
BG-9719,BG9719,BG 9719,CVT124,CVT-124,CVT 124 |
||
Adentri is a novel antagonist of adenosine A1 receptor with unique diuretic activity. | |||
T20104 |
C.I. 37545
NSC 37618,Brenthol FO,Naphtanilide BG,Acna Naphthol BG,Azoic dyes |
||
C.I. 37545 is also known as Azoic dyes. C.I. 37545 is impregnated cotton with an alkaline solution of β-naphthol, then treated it with a diazo solution obtained from aniline, a toluidine, xylidine, naphthylamine, aminoazobenzene or aminoazotoluene, so tha | |||
T78298 |
Alefacept
LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273 |
||
Alefacept (BG 9273)为一种人类淋巴细胞功能相关抗原3/免疫球蛋白1融合蛋白,主要在慢性斑块状银屑病研究中使用。 | |||
T33600 |
Naxifylline
CVT 124,CVT-124,CVT124,BG9719 |
||
Naxifylline is an A1 adenosine receptor antagonist that promotes urine volume to prevent the decline in renal function observed during diuretic therapy for the treatment of edema associated with congestive heart failure. | |||
T4618 |
BGG463
K 0859 |
Bcr-Abl; CDK | Angiogenesis; Cell Cycle/Checkpoint; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors |
BGG463 (K 0859) 是一种具有口服活性的 II 型 CDK2的抑制剂,可抑制 c-ABL-T334I、BCR-ABL 和 BCR-ABL-T315I 变体,IC50分别为 0.25 μM、0.09 μM 和 0.590 μM。 | |||
T6072 |
BGT226 maleate
BGT226,NVP-BGT226 (maleate),NVP-BGT226 |
Apoptosis; PI3K; mTOR; Autophagy | Apoptosis; Autophagy; PI3K/Akt/mTOR signaling |
BGT226 maleate (NVP-BGT226) 是一种 PI3K/mTOR 双抑制剂,针对 PI3Kα、PI3Kβ、PI3Kγ的 IC50分别是4 nM、63 nM、38 nM,对人头颈癌细胞具有较强的生长抑制活性。 | |||
T4502 |
BISMUTH SUBGALLATE
次没食子酸铋,Dermatol Puder,Bismuth Gallate |
Others | Others |
Bismuth subgallate (Dermatol Puder) 是一种止血剂,可作用于凝血因子 XII ,促使凝血级联的激活,改善纤维蛋白凝块的早期形成。 | |||
T8993L |
BGC-20-1531 hydrochloride(1186532-61-5 free base)
BGC-20-1531 hydrochloride,GTPL3380 hydrochloride,AP-1531 hydrochloride |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
BGC-20-1531 hydrochloride(1186532-61-5 free base) (GTPL3380 hydrochloride) 是一种 EP4 拮抗剂,用于治疗急性偏头痛。 | |||
T6072L |
BGT226
BGT226 free base,NVP-BGT226 |
PI3K; mTOR; Autophagy | Autophagy; PI3K/Akt/mTOR signaling |
BGT226 (NVP-BGT226) 是一种PI3K/mTOR 双抑制剂,对PI3Kα、PI3Kβ和PI3Kγ的IC50分别是4 nM、63 nM 和38 nM。它有效抑制人头颈癌细胞的生长。 | |||
T3649 |
BGP-15
BGP15,BGP-15 2HCl |
PARP | Chromatin/Epigenetic; DNA Damage/DNA Repair |
BGP-15 (BGP-15 2HCl) 是一种PARP 抑制剂,IC50和Ki 值分别为 120 和 57 μM,在缺血再灌注损伤后具有保护作用。 | |||
T10531 |
BGB-102
JNJ-26483327 |
EGFR; VEGFR; FLT; Src | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
BGB-102 (JNJ-26483327) 是一种针对FLT3 和 YES1 的激酶抑制剂和 针对 EGFR 和 VEGFR3 的拮抗剂,可用于研究黄斑变性和与遗传病与畸形相关的疾病。 | |||
T23787 |
BGT1-IN-9
BGT1 IN 9,BGT1 inhibitor 9,BGT1IN9,BGT1-inhibitor-9 |
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BGT1-IN-9 is an M1 muscarinic agonist. | |||
T38538 |
BGN3
|
||
BGN3 is a good substrate for the SNAP- tag and H 5 enzymes. The activities of SNAP- tag and H 5 enzymes on BGN3 are reasonable (IC 50 = 15.6 and 23.5 μM, respectively). | |||
T23786 |
BGB659
BGB 659,BGB-659 |
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BGB659 is effective inhibitor of RAF. | |||
T39468 |
PYBG-TMR
|
||
PYBG-TMR, a fluorochrome, serves as a dye that specifically and efficiently labels genetically encoded SNAP-tags in live cells. | |||
T32369 | KBG 4 | ||
KBG 4 is a bioactive chemical. | |||
T40788 |
PYBG
|
||
PYBG serves as a flexible precursor for facile conjugation with diverse fluorescent dyes using 'Click chemistry' and Sonogashira coupling reactions. | |||
T22044 |
BGC 20-761
|
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BGC20-761 是一种选择性的5-HT6和多巴胺受体 (dopamine receptor) 拮抗剂,对人 5-HT6,5-HT2A,D2 受体的Ki 值分别为 20,69,和 140 nM。BGC20-761 可增强长期记忆。BGC20-761 具有作为抗精神病药物的潜在效用。 | |||
T63316 |
BGC-20-1531 free base
|
||
BGC-20-1531 (PGN 1531) free base 是选择性的、有效的前列腺素 EP4受体拮抗剂 (pKB: 7.6),表现出偏头痛的研究潜力。 | |||
T74238 |
BGTC
|
||
BGTC 是一种非氨基酸阳离子脂质。BGTC 可用于核酸递送。 | |||
T8993 |
BGC201531
AP-1531,GTPL3380,BGC-20-1531 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
BGC201531 (AP-1531) 是一种 EP4 拮抗剂,用于治疗急性偏头痛。 | |||
T39469 |
PYBG-BODIPY
|
||
PYBG-BODIPY, a fluorochrome dye, specifically and efficiently labels genetically encoded SNAP-tags in live cells, serving its role as a targeted marker. | |||
T69268 |
BGC-638
|
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BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)–overexpressing tumors. | |||
T62485 |
FabG1-IN-1
|
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FabG1-IN-1 (Compound 29) 是一种 MabA(FabG1) 的有效抑制剂 (IC50: 38 μM)。 | |||
T79156 |
(R)-SKBG-1
|
Androgen Receptor | Endocrinology/Hormones |
(R)-SKBG-1为RNA结合蛋白NONO的抑制剂,能够抑制雄激素受体表达,并对AR-FL mRNA及AR-V7 mRNA具有IC50。 | |||
T27987 |
mCPBG
m-Chlorophenylbiguanide |
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mCPBG is a potent high affinity agonist of 5-HT3 receptor. | |||
T73381 |
BGB-8035
|
||
BGB-8035 是一种口服有效,高选择性BTK 抑制剂,对 BTK、TEC、EGFR 的IC50分别为 1.1 nM、99 nM、621 nM。BGB-8035 具有抗肿瘤和抗关节炎活性。BGB-8035 具有用于 B 细胞恶性肿瘤和自身免疫性疾病研究的潜力。 | |||
T9543 |
Syk Inhibitor II hydrochloride
|
Others | Others |
Syk Inhibitor II hydrochloride 信号传导的影响在狼疮中可能很突出。 | |||
T76825 | Ruplizumab | ||
Ruplizumab (BG 9588) 是一种人源化单克隆抗 CD40L(TNF Receptor) IgG1κ 抗体。Ruplizumab 具有用于系统性红斑狼疮疾病研究的潜力。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01278 |
Apolipoprotein H/APOH Protein, Human, Recombinant (His)
BG,apolipoprotein H (beta-2-glycoprotein I),B2G1,ap... |
Human | HEK293 Cells |
Apolipoprotein H/APOH Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.7 kDa and the accession number is A0A384NKM6. | |||
TMPY-03418 |
Biglycan Protein, Mouse, Recombinant (hFc)
PGI,PG-S1,DSPG1,BG,biglycan,SLRR1A |
Mouse | HEK293 Cells |
Biglycan Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.5 kDa and the accession number is P28653. | |||
TMPK-01328 |
Apolipoprotein H/APOH Protein, Cynomolgus, Recombinant (His)
B2GPI,B2G1,BG,B2GP1,APOH,beta(2)GPI,β(2)GPI,Apo-H |
Cynomolgus | HEK293 Cells |
Apolipoprotein (apo)H (also known as beta 2 glycoprotein-I) is a glycoprotein synthesized by liver cells and it is present in the blood associated with plasma lipoproteins. APOH displays a genetically determined structural polymorphism: three alleles (APOH*1, APOH*2, APOH*3) at a single locus on chromosome 17 code for different isoforms, and population studies have shown that APOH*2 is the most frequent allele. | |||
TMPY-04506 |
A1BG Protein, Human, Recombinant (His)
alpha-1-B glycoprotein,GAB,α-1-B glycoprotein,HYST2477,A1B,A... |
Human | HEK293 Cells |
A1BG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.4 kDa and the accession number is P04217-1. | |||
TMPY-05033 |
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
5T4AG,trophoblast glycoprotein,WAIF1,M6P1,5T4 |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641. | |||
TMPK-00271 |
TPBG/5T4 Protein, Human, Recombinant (His & Avi)
M6P1,WAIF1,5T4,TPBG,5T4AG |
Human | HEK293 Cells |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. TPBG/5T4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is Q13641-1... | |||
TMPJ-01153 |
5T4/TPBG Protein, Cynomolgus, Recombinant (His)
TPBG,5T4,M6P1,WAIF1,5T4AG |
Cynomolgus | HEK293 Cells |
5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9. | |||
TMPY-01256 |
TBG Protein, Human, Recombinant (His)
Serpin A7,serpin peptidase inhibitor, clade A (α-1 antiprote... |
Human | HEK293 Cells |
TBG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.5 kDa and the accession number is P05543. | |||
TMPH-02107 |
SH3BGRL Protein, Human, Recombinant (GST & His)
|
Human | E. coli |
SH3BGRL Protein, Human, Recombinant (GST & His) is expressed in E. coli. | |||
TMPH-02436 |
5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)
TPBG,Trophoblast glycoprotein,Wnt-activated inhibit... |
Cynomolgus | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.9 kDa and the accession number is Q4R8Y9. | |||
TMPJ-00268 |
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated
5T4,M6P1,WAIF1,5T4AG,TPBG |
Human | HEK293 Cells |
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 60-90 KDa and the accession number is Q13641. | |||
TMPY-01240 |
TBG Protein, Mouse, Recombinant (His)
serpin peptidase inhibitor, clade A (α-1 antiproteinase, ant... |
Mouse | HEK293 Cells |
TBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.2 kDa and the accession number is Q3UEL9. | |||
TMPJ-00269 |
5T4/TPBG Protein, Human, Recombinant (mFc)
TPBG,5T4 Protein,M6P1 Protein,5T4AG Protein,WAIF1 P... |
Human | HEK293 Cells |
5T4/TPBG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-110 KDa and the accession number is Q13641. | |||
TMPK-00270 |
TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled
WAIF1,TPBG,5T4AG,5T4,M6P1 |
Human | HEK293 Cells |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.2 kDa and the accession numb... | |||
TMPH-03392 |
5T4/TPBG Protein, Rat, Recombinant (His & SUMO)
Wnt-activated inhibitory factor 1,Trophoblast glycoprotein,T... |
Rat | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.8 kDa and the accession number is Q5PQV5. | |||
TMPY-06317 |
5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)
trophoblast glycoprotein,WAIF1,5T4AG,M6P1,5T4 |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.15 kDa and the accession number is NP_006661.1. | |||
TMPJ-01297 |
WIBG Protein, Human, Recombinant (His)
Protein Wibg Homolog,Partner of Y14 and Mago,WI... |
Human | E. coli |
Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs, is a positional landmarker for the intron exon structure of genes, and directs post-transcriptional processes in the cytoplasm, for instance mRNA export, nonsense-mediated mRNA decay or translation. WIBG is a cytoplasmic RNA-binding protein, it can be excluded from nucleus by Crm1. WIBG as a cooperateing partn... | |||
TMPH-01435 |
Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Hemoglobin subunit gamma-1/HBG1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.0 kDa and the accession number is P69891. | |||
TMPY-06214 |
5T4/TPBG Protein, Mouse, Recombinant (hFc)
trophoblast glycoprotein,AW495680,5T4,WAIF1 |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9Z0L0. | |||
TMPY-06191 |
5T4/TPBG Protein, Mouse, Recombinant (His)
trophoblast glycoprotein,WAIF1,5T4,AW495680 |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9Z0L0. | |||
TMPH-00564 |
FabG Protein, E. coli, Recombinant (His & Myc)
|
E. coli | E. coli |
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. | |||
TMPH-02437 |
5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)
TPBG,WAIF1,Wnt-activated inhibitory factor 1,Tropho... |
Cynomolgus | HEK293 Cells |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 39.9 kDa and the accession number is Q4R8Y9. |