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59

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T0786	Clidinium bromide 克利溴铵,Ro 2-3773	AChR	Neuroscience
	Clidinium bromide (Ro 2-3773) 是季胺抗毒蕈碱剂，可通过减少胃酸和减慢肠道速度，缓解痉挛和腹部疼痛的症状。
TP1086	Men 10376 TFA(135306-85-3,free) Men 10376 TFA,Neurokinin-2 receptor antagonist TFA	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Men 10376 TFA(135306-85-3,free) (Neurokinin-2 receptor antagonist TFA) 是一种有效的选择性速激肽 nk-2 受体拮抗剂，对大鼠小肠 nk-2 受体的 K I 值为 4.4 M。
TP2017L	GIP (1-39) acetate GIP (1-39) acetate(725474-97-5 Free base)	Others	Others
	GIP (1-39) acetate 是一种从猪肠道中纯化的胃抑制肽 (GIP)，可刺激胰岛素分泌。
T3433	TUG-891 TUG 891,TUG891	GPR	Endocrinology/Hormones; GPCR/G Protein
	TUG-891 是一种选择性的长链游离脂肪酸受体 4 (FFA4/GPR120) 的激动剂。
T38648L	Cecropin P1, porcine acetate	Endogenous Metabolite	Metabolism
	Cecropin P1, porcine acetate 是一种在 Hyalophora cecropia 和猪肠道中发现的抗菌肽。
TP1835L	Enterostatin, human, mouse, rat acetate	Endogenous Metabolite	Metabolism
	Enterostatin, human, mouse, rat acetate 是一种五肽，主要由分泌的胰腺前脂肪酶在肠道中形成。
T21867	BI-6015 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑	Others	Others
	BI 6015 是肝细胞核因子 4α (HNF4α) 拮抗剂，可抑制已知 HNF4α 靶基因的表达。它利用 HNF4α 拮抗作用，降低胰岛素启动子活性，可用于研究癌症和糖尿病。
T1291	Cisapride 西沙必利,西沙比利,Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase	Potassium Channel; 5-HT Receptor; HER	Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Tyrosine Kinase/Adaptors
	Cisapride (R 51619) 是一种5-HT4受体激动剂，还是 hERG 抑制剂。它可作用于肠道中的血清素受体，促进肠道蠕动，增加胃排空并减少食管反流。
TP2419	V-9-M Cholecystokinin nonapeptide V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M	Beta Amyloid	Neuroscience
	V-9-M Cholecystokinin nonapeptide (Prepro CCK Fragment V-9-M) 是胆囊收缩素(CCK)的前体化合物。胆囊收缩素(CCK)是一种刺激胆囊收缩和胰腺外分泌的脑肠肽，可从狗和猫的小肠中提取的，可以引起胆囊收缩。
T3625	Bempedoic acid ETC1002,ESP-55016,ETC 1002,ETC-1002	ATP Citrate Lyase; AMPK	Chromatin/Epigenetic; Metabolism; PI3K/Akt/mTOR signaling
	Bempedoic acid (ETC1002) 是一种 ATP-柠檬酸裂解酶抑制剂，可激活AMPK。它是脂质和碳水化合物代谢的调节剂。
T36503	Sodium Hydrogen Sulfide (hydrate)	Others	Others
	Sodium Hydrogen Sulfide (hydrate) 与一氧化氮一样，是一种重要的气体介质，对哺乳动物的免疫、神经、心血管和肺系统有重要影响。Sodium Hydrogen Sulfide (hydrate)是一种H2S 供体，常用于细胞和整个动物实验系统。例如，它被用来证明H2S 促进中性粒细胞迁移，减少气道炎症，保护神经轴突、心脏和肠道免受化学或缺血再灌注损伤。
T5943	4,4'-DIMETHOXYBENZIL p-Anisil,4,4'-二甲氧基苯酚酯	Others	Others
	4,4'-Dimethoxybenzil (trans-4-Sphingenine) 是人肠胃羧基酯酶抑制剂(Ki:70 nM)。
T37299	L-Palmitoylcarnitine chloride
	Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant...
T67956L	Litoxetine HCl litoxetine HCL(86811-09-8 Free base)	5-HT Receptor	GPCR/G Protein; Neuroscience
	Litoxetine HCl 是一种选择性5-羟色胺（5-HT）再摄取抑制剂（SSRI）和混合5-羟色胺拮抗剂，可用于治疗尿失禁。Litoxetine HCl 在没有抗毒蕈碱特性的浓度下（10 nM-1 microM）引起大鼠离体食道肌肉粘膜的浓度依赖性松弛，使卡巴胆碱张力降低达37%,更高浓度的Litoxetine HCl（3微摩-300微摩）与明显的松弛有关，直至取消卡巴胆碱张力。以前在离体豚鼠肠道中证明的利托西汀的抗心律失常活性，在浓度大于1 microM 时在大鼠离体食道肌肉粘膜中发挥了作用。 Litoxetine HCl 的5-HT 释放作用可以解释利托西汀对未处理的大鼠组织中的5-HT 诱导的松弛的效力，这种效力被pCPA 处理所逆转。
T16038	Men 10376 Neurokinin-2 receptor antagonist	CDK	Cell Cycle/Checkpoint
	Men 10376 is a selective antagonist of tachykinin NK-2 receptor. It has a Ki of 4.4 μM for rat small intestine NK-2 receptor.
T70048	Sch 58053
	Sch 58053 is an analog of Ezetimibe and a selective inhibitor of lymphatic cholesterol transport in the intestine.
T71161	Thiorphan disulfide
	Thiorphan disulfide is an impurity of Racecadotril -- an antidiarrheal and enkephalinase inhibitor that reduces the amount of water and electrolytes absorbed into the intestine.
T31522	Dipropyl sulfone
	Dipropyl sulfone may function as an enhancer of heparin absorption in the intestine.
T15462	Haloxon	Others	Others
	Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.
T37204	CCK (26-31) (non-sulfated)
	CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.
T38648	Cecropin P1, porcine
	Cecropin P1, porcine is an antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.
T69033	Magnesium Oxaloacetate
	Magnesium Oxaloacetate is an inhibitor of the amebicidal activity of activated murine macrophages, helping the parasite to survive within the mouse large intestine and increasing the survival of C. elegans exposed to H2O2.
T39187	Gliadin p31-43 Gliadin p31-43
	Gliadin p31-43, an undigested peptide derived from gliadin, prompts an innate immune response in the intestine and disrupts endocytic trafficking. Moreover, its utilization in celiac disease research has proven beneficial.
T82308	GLP-2 (1-34) (human)
	GLP-2 (1-34) (human) 是一种肠道多肽，其在进食后数分钟内释放，并可用于研究骨重塑过程。
T41028	α-Glucosidase α-D-Glucosidase,α-葡萄糖苷酶
	α-Glucosidase (α-D-Glucosidase) is a carbohydrate hydrolyzing enzyme that catalyzes the release of α-glucose from the non-reducing end of the substrate. It plays a vital role in facilitating glucose absorption by the small intestine. Inhibiting α-Glucosidase effectively manages non-insulin-dependent diabetes mellitus (NIDDM).
T80881	Valosin (porcine)
	Valosin (porcine)是一种含有25个氨基酸的生物活性肽，最近从猪肠中分离得到，主要用于消化系统研究。
T82311	Gliadin p31-43 TFA
	Gliadin p31-43 TFA 是一种未消化gliadin peptide，可诱导肠道先天性免疫反应并干扰内吞运输，用于乳糜泻研究。
T75786	Enterostatin(human,mouse,rat) TFA
	Enterostatin (human,mouse,rat) TFA, 作为一种五肽，主由胰前脂酶在肠道中裂解生成。它能选择性降低脂肪摄取、体重及体脂。
T37203	CCK (26-30) (sulfated)
	CCK (26-30) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% when used at a concentration of 0.1 mM.
T26237	Sulisatin DAN 603,Laxitex,DAN603,Sulisatinum,DAN-603
	Sulisatin 是一种泻药。它在大肠中被肠道菌群水解为其二苯衍生物BHMI，BHMI 负责药物的通便活性。
TP1487	Glucagon-Like Peptide (GLP) II, human
	Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Glucagon-Like Peptide 2 is used as a po
T70605	NaPi2b Inhibitor 15
	NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. The inhibition of NaPi2b, responsible for intestinal phosphate absorption, is considered to reduce serum phosphate levels, making it a promising therapeutic approach for hyperphosphatemia
T69066	Forphenicine
	Forphenicine is a bacterial metabolite that has been found in S. fulvoviridis and an inhibitor of alkaline phosphatase (IC50 = 0.036 µg/ml for the chicken intestine enzyme). It inhibits the growth of HL-60 leukemia cells when used at a concentration of 10 µM. Forphenicine (50 and 500 µg/animal) increases survival in a guinea pig model of experimental autoimmune encephalomyelitis (EAE).
T60641	Vanin-1-IN-2
	Vanin-1-IN-2 是vanin-1的有效抑制剂(IC 50 = 162 nM)。Vanin-1 是在肾脏、肝脏和小肠中高水平表达的细胞表面相关的糖基磷脂酰肌醇 (GPI) 锚定蛋白。
T71340	Mizagliflozin sebacate
	Mizagliflozin sebacate is a sodium-glucose transporter inhibitor. It is expected to improve postprandial hyperglycemia by suppressing glucose absorption from the intestine with a novel mechanism of action different from that of conventional alpha-glucosidase inhibitors. Mizagliflozin blocks intestinal glucose absorption and reduce GIP secretion in rats and humans, suggesting SGLT1 glucose transport is critical for GIP release.
T63819	Domperidone monomaleate
	Domperidone (R33812) monomaleate 是选择性的、口服具有活力的多巴胺-2 受体 (dopamine-2 receptor) 拮抗剂。Domperidone monomaleate 能够影响胃和小肠的化学感受器触发区和运动功能，具有止吐和促动力剂作用。
T37205	CCK (26-31) (sulfated)
	CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. The sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% when used at a concentration of 0.1 mM.
T75879	Men 10376 TFA
	Men 10376 TFA 是一种有效的选择性的 tachykinin NK-2受体拮抗剂，对大鼠小肠 NK-2 受体的Ki 值为 4.4 μM。
T75823	GLP-2(rat) TFA
	GLP-2(rat) TFA为肠道生长因子，能刺激细胞增殖、抑制凋亡，且在大肠小肠切除术(MSBR)后，可提升残留小肠粘膜的品质与功能。
T76001	Apraglutide TFA
	Apraglutide TFA (FE 203799 TFA) 是一种合成的、含33个氨基酸的肽类药物，为长效GLP-2类似物。它能在全回肠切除后导致的新生短肠综合征小猪中增强适应性和线性肠生长。
T0366L	Cefadroxil (hydrate)
	Cefadroxil is a first generation aminocephalosporin with good patient compliance, a long-acting therapeutic effect, high solubility and relatively broad spectrum of anti-bacterial activity. Cefadroxil is also a substrate of the intestinal peptide transporter PepT1, which is primarily responsible for the drug's uptake across the apical membrane of small intestine.
T37021	Enteropeptidase Fluorogenic Substrate
	Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage. Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ac...
T81539	PAT1inh-B01
	PAT1inh-B01为选择性SLC26A6抑制剂，抑制PAT1（Cl-/HCO3-交换器）介导的阴离子交换（IC50: 350 nM），并阻断小肠液体吸收，适用于小肠分泌不足相关疾病研究。
T37022	Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)
	Enteropeptidase fluorogenic substrate is a substrate for enteropeptidase that contains a 7-amino-4-trifluoromethylcoumarin (AFC) moiety. Enteropeptidase is a serine protease expressed in the proximal small intestine of higher animals that converts inactive trypsinogen to active trypsin by endoproteolytic cleavage.1,2Enteropeptidase recognizes the highly specific amino acid sequence DDDDK on the fluorogenic substrate and cleaves after the lysine residue, releasing the AFC moiety. Enteropeptidase ...
T37519	Diquat (bromide)
	Diquat is a bipyridylium herbicide that, as a stable radical, acts as an electron acceptor in the electron transport chain and is reoxidized by molecular oxygen, producing reactive oxygen species (ROS).1Diquat administration has been used to induce oxidative stressin vitroand in animal models.2,3,4It increases the production of ROS and decreases the mitochondrial membrane potential in mitochondria isolated from porcine intestine leading to mitophagy when administered at a dose of 100 mg/kg.2Form...
T37757	Tyvelose
	Tyvelose is an unusual 3,6-dideoxyhexose terminal sugar and the immunodominant component of glycoprotein antigens in the parasitic helminth T. spiralis, which is responsible for trichinosis in humans. It is produced in high amounts by the infective larva and is immunodominant during the muscle stage of infection. Mice immunized with tyvelose-BSA produce IgG1 antibodies to tyvelose but are not resistant to infection by T. spiralis. Tyvelose-specific antibodies (2.5 mg/20 g) administered to rat pu...
T64553	GLP-1(7-37) TFA salt
	The truncated glucagon-like peptides GLP-1(7-37) is naturally occurring peptide product of the preproglucagon gene that are synthesized primarily in the intestine and acts as incretin that are released from the intestine into the bloodstream in response to food and stimulate insulin secretion. GLP-1(7-37) produced a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in Sprague-Dawley Rats at a dosing rang of 0.5, ...
T38291	C24 Phytosphingosine (t18:0/24:0)
	C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the inco...
T37206	CCK (27-33) (non-sulfated)
	CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in m...
T38180	C16 Phytoceramide (t18:0/16:0)
	C16 Phytoceramide (t18:0/16:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C16 Phytoceramide (t18:0/16:0) is composed of a phytosphingosine backbone amine-linked to a C16 fatty acid chain. The levels of C16 phytoceramide (t18:0/16:0) increase following heat stress in S. cerevisiae. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous ...

化合物

Clidinium bromide

Cat.No: T0786

Synonym: 克利溴铵,Ro 2-3773

Target: AChR

Men 10376 TFA(135306-85-3,free)

Cat.No: TP1086

Synonym: Men 10376 TFA,Neurokinin-2 receptor antagonist TFA

Target: Neurokinin receptor

GIP (1-39) acetate

Cat.No: TP2017L

Synonym: GIP (1-39) acetate(725474-97-5 Free base)

Target: Others

Cat.No: T3433

Synonym: TUG 891,TUG891

Target: GPR

Cecropin P1, porcine acetate

Cat.No: T38648L

Target: Endogenous Metabolite

Enterostatin, human, mouse, rat acetate

Cat.No: TP1835L

Target: Endogenous Metabolite

Cat.No: T21867

Synonym: 2-甲基-1-(2-甲基-5-硝基苯基磺酰基)-1H-苯并[D]咪唑

Target: Others

Cat.No: T1291

Synonym: 西沙必利,西沙比利,Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase

Target: Potassium Channel, 5-HT Receptor, HER

V-9-M Cholecystokinin nonapeptide

Cat.No: TP2419

Synonym: V 9 M,Prepro CCK Fragment V-9-M,Val-pro-val-glu-ala-val-asp-pro-met,Cholecystokinin Precursor (24-32),V9M,V-9-M

Target: Beta Amyloid

Cat.No: T3625

Synonym: ETC1002,ESP-55016,ETC 1002,ETC-1002

Target: ATP Citrate Lyase, AMPK

Sodium Hydrogen Sulfide (hydrate)

Cat.No: T36503

Target: Others

4,4'-DIMETHOXYBENZIL

Cat.No: T5943

Synonym: p-Anisil,4,4'-二甲氧基苯酚酯

Target: Others

L-Palmitoylcarnitine chloride

Cat.No: T37299

Cat.No: T67956L

Synonym: litoxetine HCL(86811-09-8 Free base)

Target: 5-HT Receptor

Cat.No: T16038

Synonym: Neurokinin-2 receptor antagonist

Target: CDK

Cat.No: T70048

Thiorphan disulfide

Cat.No: T71161

Dipropyl sulfone

Cat.No: T31522

Cat.No: T15462

Target: Others

CCK (26-31) (non-sulfated)

Cat.No: T37204

Cecropin P1, porcine

Cat.No: T38648

Magnesium Oxaloacetate

Cat.No: T69033

Cat.No: T39187

Synonym: Gliadin p31-43

GLP-2 (1-34) (human)

Cat.No: T82308

Cat.No: T41028

Synonym: α-D-Glucosidase,α-葡萄糖苷酶

Valosin (porcine)

Cat.No: T80881

Gliadin p31-43 TFA

Cat.No: T82311

Enterostatin(human,mouse,rat) TFA

Cat.No: T75786

CCK (26-30) (sulfated)

Cat.No: T37203

Cat.No: T26237

Synonym: DAN 603,Laxitex,DAN603,Sulisatinum,DAN-603

Glucagon-Like Peptide (GLP) II, human

Cat.No: TP1487

NaPi2b Inhibitor 15

Cat.No: T70605

Cat.No: T69066

Cat.No: T60641

Mizagliflozin sebacate

Cat.No: T71340

Domperidone monomaleate

Cat.No: T63819

CCK (26-31) (sulfated)

Cat.No: T37205

Cat.No: T75879

Cat.No: T75823

Apraglutide TFA

Cat.No: T76001

Cefadroxil (hydrate)

Cat.No: T0366L

Enteropeptidase Fluorogenic Substrate

Cat.No: T37021

Cat.No: T81539

Enteropeptidase Fluorogenic Substrate (trifluoroacetate salt)

Cat.No: T37022

Diquat (bromide)

Cat.No: T37519

Cat.No: T37757

GLP-1(7-37) TFA salt

Cat.No: T64553

C24 Phytosphingosine (t18:0/24:0)

Cat.No: T38291

CCK (27-33) (non-sulfated)

Cat.No: T37206

C16 Phytoceramide (t18:0/16:0)

Cat.No: T38180

Cat. No.	Product Name	Target	Signaling Pathways
TJS0928	Calenduloside E 去葡萄糖竹节参皂苷,Silphioside F	Others	Others
	Calenduloside E (Silphioside F) 是从辽东楤木中提取的一种五环三萜皂苷。它靶向热休克蛋白90 (Hsp90) ，具有抗凋亡作用。
TN1528	Cotoin	AChE	Neuroscience
	Cotoin 是从 Garcinia virgate 茎皮中分离出的一种天然产物。Cotoin 具有解痉活性，可降低孤立的兔肠的音调和收缩。它部分抑制乙酰胆碱、毛果芸香碱和 BaCl 对分离肠的影响。
T1016	D-α-Tocopherol acetate 乙酸维生素E,Vitamin E Acetate,Tocopherol acetate	Endogenous Metabolite	Metabolism
	D-α-Tocopherol acetate (Vitamin E Acetate) 能够水解为 d-α-生育酚 (VE) 并被小肠吸收。
T2S1840	Rebaudioside D 莱苞迪苷D,瑞鲍迪甙D	Others	Others
	Rebaudioside D 是一种苷类化合物，存在于甜菊叶中，可用作甜味剂。
T0966	Sennoside A 番泻苷A,NSC 112929,番泻苷 A	MAO; HIV Protease	Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Sennoside A (NSC-112929) 是在番泻叶的叶子和豆荚中大量发现的蒽醌苷，抑制 HIV-1 复制。
T2215	Ferulic Acid Coniferic acid,Fumalic Acid,阿魏酸	FGFR; Endogenous Metabolite	Angiogenesis; Metabolism; Tyrosine Kinase/Adaptors
	Ferulic Acid (Coniferic acid) 是新型的成纤维细胞生长因子受体 1 (FGFR1)抑制剂, 在FGFR1和FGFR2的IC50分别为 3.78 和 12.5 μM。
TN6393	fulvotomentoside A	Others	Others
	fulvotomentoside A 可降低肠道中 IL-6 和 IL-17A 的过表达，并显着增加调节性 T 细胞特异性转录因子 Foxp3 的表达。这可能是Ful 改善肠道炎症的机制之一。
T3S0509	Gaultherin	COX	Immunology/Inflammation; Neuroscience
	Gaultherin 是一种分离自 Gaultheria yunnanensis 中的天然水杨酸酯衍生物。它是一种非甾体类抗炎药，具有止痛和抗炎作用，与 Aspirin 相比没有胃溃疡作用。
T15824	Lysergol	Antibacterial	Microbiology/Virology
	Lysergol 已被用作一种降血压、精神镇痛药以及刺激子宫和肠道的药物。 Lysergol 是从 Ipomoea muricata 的种子中分离出来的一种棒状生物碱，是药物和营养物质的生物增强剂，具有抗菌活性。
T13506	3β-Ursodeoxycholic acid Isoursodeoxycholic acid
	3β-Ursodeoxycholic acid (Isoursodeoxycholic acid) 是一种胆汁酸。3β-Ursodeoxycholic acid 经口服给药表现出良好的耐受性和良好的肠道吸收能力。3β-Ursodeoxycholic acid 可以在肠道和肝脏经历酶异构化，并生成UDCA。
T19124	3-Oxocholic acid 3-Ketocholic acid	Endogenous Metabolite	Metabolism
	3-Oxocholic acid(3-Ketocholic acid) 是胆汁酸的代谢产物，也是产气荚膜梭菌在肠道中由胆汁降解的主要产物。33-Oxocholic acid 是一种主要存在于哺乳动物的胆汁中类固醇酸。
T0847	Chenodeoxycholic acid CDCA,鹅去氧胆酸,Chenodiol	Potassium Channel; FXR; Endogenous Metabolite; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Chenodeoxycholic acid (CDCA) 是一种胆汁酸，通常与甘氨酸或牛磺酸结合。它作为清洁剂溶解脂肪以供肠道吸收，并被小肠重新吸收。它被用作利胆剂、利胆泻药，以及预防或溶解胆结石。
T5S1988	Isorhamnetin-3-O-glucoside Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷	Others	Others
	Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) 是一种天然化合物，广泛存在于蔬菜和水稻中，经消化后可在肠道菌群中代谢。
T3S1967	(S)-Indoximod N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine	Others; Indoleamine 2,3-Dioxygenase (IDO)	Metabolism; Others
	(S)-Indoximod (L-Abrine) 是一种吲哚胺-2,3-双加氧酶 (IDO) 抑制剂，可用于研究癌症。
T1040	Vitamin B12 Cyanocobalamin,Cobalamin,维生素B12	Endogenous Metabolite	Metabolism
	Vitamin B12 (Cobalamin) 是一种维生素，在维持血流形成和脑、神经系统正常功能等方面发挥关键作用。
TJS0387	Desoxyrhaponticin 去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin	Apoptosis; Fatty Acid Synthase	Apoptosis; Metabolism
	Desoxyrhaponticin (Deoxyrhaponticin) 是来自西藏营养食品唐古特大黄中的一种二苯乙烯苷。它是脂肪酸合成酶抑制剂，抑制细胞内 FAS 活性，下调人乳腺癌 MCF-7细胞中 FAS 的表达。它是控制糖尿病餐后高血糖的潜在药物。
T74293	Allolithocholic acid
	Allolithocholic acid 是一种类固醇酸，在正常血清和粪便中可发现。该化合物促进脂肪与甾醇在肠道及肝脏的排泄、吸收与运输。
T82032	Isoglobotriaose Gala-3Galb-4Glc
	Isoglobotriaose (Gala-3Galb-4Glc)是哺乳动物组织中的一种糖鞘脂，属于球状三脂糖的类似物。其神经节苷脂衍生物isoglobotriaosylceramide特定分布于小肠非上皮细胞的残基中，而globotriaosylceramide则在两种细胞隔室中都有分布。
T37810	6',7'-Epoxybergamottin
	6'7'-Epoxybergamottin is a furanocoumarin found in grapefruit. It is a potent inhibitor of the cytochrome P450 (CYP) isoform CYP3A4 with an IC50 value of 0.30 ppm in a cell-free assay, 0.33 μM in HL7 human liver cells, and 0.22 μM in S9 human intestine cells. It has been studied in the context of drug interactions with grapefruit constituents. It is found in grapefruit juice at concentrations of 0.1-7.4 μM and inhibits the transport of talinolol , a permeability glycoprotein (P-gp/ABCB1) transpo...

天然产物

Calenduloside E

Cat.No: TJS0928

Synonym: 去葡萄糖竹节参皂苷,Silphioside F

Target: Others

Cat.No: TN1528

Target: AChE

D-α-Tocopherol acetate

Cat.No: T1016

Synonym: 乙酸维生素E,Vitamin E Acetate,Tocopherol acetate

Target: Endogenous Metabolite

Cat.No: T2S1840

Synonym: 莱苞迪苷D,瑞鲍迪甙D

Target: Others

Cat.No: T0966

Synonym: 番泻苷A,NSC 112929,番泻苷 A

Target: MAO, HIV Protease

Cat.No: T2215

Synonym: Coniferic acid,Fumalic Acid,阿魏酸

Target: FGFR, Endogenous Metabolite

fulvotomentoside A

Cat.No: TN6393

Target: Others

Cat.No: T3S0509

Target: COX

Cat.No: T15824

Target: Antibacterial

3β-Ursodeoxycholic acid

Cat.No: T13506

Synonym: Isoursodeoxycholic acid

3-Oxocholic acid

Cat.No: T19124

Synonym: 3-Ketocholic acid

Target: Endogenous Metabolite

Chenodeoxycholic acid

Cat.No: T0847

Synonym: CDCA,鹅去氧胆酸,Chenodiol

Target: Potassium Channel, FXR, Endogenous Metabolite, Autophagy

Isorhamnetin-3-O-glucoside

Cat.No: T5S1988

Synonym: Isorhamnetin-3-O-beta-D-Glucoside,异鼠李素-3-O-葡萄糖苷

Target: Others

Cat.No: T3S1967

Synonym: N-ME-Tryptophan,Abrine,相思豆碱,L-Abrine

Target: Others, Indoleamine 2,3-Dioxygenase (IDO)

Cat.No: T1040

Synonym: Cyanocobalamin,Cobalamin,维生素B12

Target: Endogenous Metabolite

Desoxyrhaponticin

Cat.No: TJS0387

Synonym: 去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin

Target: Apoptosis, Fatty Acid Synthase

Allolithocholic acid

Cat.No: T74293

Isoglobotriaose

Cat.No: T82032

Synonym: Gala-3Galb-4Glc

6',7'-Epoxybergamottin

Cat.No: T37810

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