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Search Results for " antiprotozoal "

41

抑制剂 & 化合物

22

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T5052	Toltrazuril (sulfone) Toltrazuril sulfone,妥曲珠利砜,Ponazuril	Parasite	Microbiology/Virology
	Toltrazuril sulfone (Ponazuril) 是 Toltrazuril 的代谢物，是一种抗原生动物剂。它是一种三嗪类抗球虫剂，用于预防家禽球虫病。
T21899	Misonidazole SR-1354,SR1354,Ro 7-0582	GPX	oxidation-reduction
	Misonidazole 是一种缺氧肿瘤细胞放射增敏剂，具有抗菌活性。
T9233	Metronidazole acetic acid	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Metronidazole acetic acid 是 Metronidazole 的代谢产物，在细菌中具有诱变活性。Metronidazole 是硝基咪唑类抗生素，杀螨剂和抗原生动物剂。
T1177	Sulfaquinoxaline 磺胺喹恶啉,Avicocid,磺胺喹噁啉,Sulphaquinoxaline,Sulfabenzpyrazine	Others; Antibacterial; Antibiotic; Parasite	Microbiology/Virology; Others
	Sulfaquinoxaline (Sulfabenzpyrazine) 是一种兽用抗菌剂，对革兰氏阴性菌和革兰氏阳性菌均有活性。它能用于预防球虫病和细菌感染。
T12223	Nifursemizone NF161,5-Nitro-2-furancarbaldehyde 2-ethyl semicarbazone,硝呋米腙,Etafurazone	Antibiotic	Microbiology/Virology
	Nifursemizone (Etafurazone) 是抗原虫药。
T1647	Ronidazole 洛硝哒唑,Ronidazol,罗硝唑,Ridzol	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ronidazole (Ronidazol) 是一种口服有效的抗原虫和抗菌试剂。它在猫模型中对胎儿三毛滴虫有效，还可研究组织口癣和猪痢疾。
T7121	Sulfaclozine 磺胺氯吡嗪,Sulfachloropyrazine,Sulfachloropyrazine sodium,N-(5-氯-3-吡嗪基)-4-氨基苯磺酰胺	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Sulfachloropyrazine sodium(Sulfachloropyrazine) 是一种磺酰胺衍生物，具有抗菌和抗球虫作用。Sulfachloropyrazine sodium(Sulfachloropyrazine) 用于各种家禽疾病。
T0751	Furazolidone 呋喃唑酮,Furoxone	Apoptosis; MAO; Antibacterial; Antibiotic	Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
	Furazolidone (Furoxone) 是一种具有抗菌和抗原虫活性的硝基呋喃衍生物，抑制AML1-ETO 转化细胞，IC50为12.7 μM。
T4982	Benznidazol 苄哒唑,苄硝唑,Radanil,Benznidazole,Ro 71051,Ro 07-1051	Antibiotic; Parasite	Microbiology/Virology
	Benznidazol (Benznidazole) 是一种抗寄生虫药物，对哥伦比亚 T. cruzi 菌株的 IC50值为 20.35 μM，有潜力研究美洲锥虫病。
T1061	Toltrazuril BAY-i 9142,Toltrazurilo,妥曲珠利,Baycox,Toltrazurilum,托曲珠利	Antibiotic; Parasite	Microbiology/Virology
	Toltrazuril (Toltrazurilo) 是一种抗原虫剂，对球虫亚纲有效。
T1526	Nifuratel NF 113,SAP 113,硝呋太尔,Methylmercadone	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Nifuratel (SAP 113) 是广谱抗生素，有抗细菌、真菌和毛滴虫活性。
T4269	Buparvaquone 布帕伐醌,Butalex,BW 720C	Antibiotic; Parasite	Microbiology/Virology
	Buparvaquone (BW 720C) 是与parvaquone 和atovaquone 有关的一种羟基萘醌类抗原虫药。
T1546	Nitazoxanide NSC 697855,硝唑尼特	Others; Influenza Virus; Parasite; Autophagy	Autophagy; Microbiology/Virology; Others
	Nitazoxanide (NSC-697855) 是一种广谱驱虫剂，对感染动物和人类的各种蠕虫、原生动物和肠道细菌都具有作用活性。它在无菌培养中抑制Giardia lamblia 滋养体增殖，IC50为 2.4 μM。它可研究寄生虫性胃肠炎，具有抗病毒特性。
T4218	Broxaldine Brobenzoxaldine,溴沙定	Antibacterial; Antibiotic; Parasite; Antifungal	Microbiology/Virology
	Broxaldine (Brobenzoxaldine) 是一种具有抗原生动物活性的小分子药物。它抑制艰难梭菌的 MIC 值为 4 µM，并具有抗真菌作用。
T5325	Nifurtimox 硝呋替莫,BAY-2502,BAY-A-2502	Dehydrogenase; Parasite	Metabolism; Microbiology/Virology
	Nifurtimox (BAY-A-2502) 是一种用于锥虫病的抗虫剂，可影响乳酸脱氢酶活性。它有潜力研究神经母细胞瘤细胞。
T20535	Carnidazole ME 108,NSC293873,NSC 293873,ME-108,NSC-293873,ME108	Antibiotic; Parasite	Microbiology/Virology
	Carnidazole (ME-108) 具有抗原生动物活性，可用于治疗滴虫感染的研究。
T0701	Broxyquinoline Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline,溴羟喹啉	Antibiotic; Parasite	Microbiology/Virology
	Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) 是一种有效的发热伴血小板减少综合症病毒 (SFTSV) 抑制剂，IC50为 5.8 µM。Broxyquinoline 是一种抗原虫药。
T1654	Pentamidine isethionate Pentamidine isethionate salt,Pentamidine diisethionate,喷他脒羟乙磺酸盐	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine isethionate (Pentamidine diisethionate) 是抗微生物剂，会干扰 DNA 的生物合成。它抑制寄生虫Leishmania infantum，IC50为 2.5 μM。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它有抗肿瘤和抗菌活性。
T23133	Pentamidine	Phosphatase; Antibacterial; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology
	Pentamidine 是抗微生物剂，会干扰 DNA 的生物合成。它是选择性蛋白酪氨酸磷酸酶和再生肝磷酸酶抑制剂。它可用于冈比亚锥虫病，抗锑利什曼病和卡氏肺孢子虫肺炎的研究，有抗肿瘤活性，抗菌活性。
T0893	Tinidazole 替硝唑,CP12574	Antibacterial; Antibiotic	Microbiology/Virology
	Tinidazole (CP12574) 是一种对厌氧菌和原生动物具有选择性抗菌活性的 5-硝基咪唑，是一种具有口服活性的抗菌剂。
T17097	Tilbroquinol	Others	Others
	Tilbroquinol is an antiprotozoal agent effective against amoebiasis.
T0896L	Levofuraltadone Levofuraltadonum,NSC527986,NSC 527986,NSC-527986,NF-602
	Levofuraltadone is an antiprotozoal and antibacterial agent.
T62210	Antileishmanial agent-10
	Antileishmanial agent-10 (Compound 7h) 是一种抗原虫 (antiprotozoal) 剂。
T19744	Isometamidium chloride A-4180,A4180,A 4180
	Isometamidium chloride is an antiprotozoal agent. It is also used in veterinary medicine.
T63869	Anti-Trypanosoma cruzi agent-3
	Anti-Trypanosoma cruzi agent-3 是一种抗原虫 (antiprotozoal) 剂。
T76257	Lefleuganan
	Lefleuganan 是一种有效的抗原虫剂 (antiprotozoal)。
T37639	Toltrazuril sulfoxide
	Toltrazuril sulfoxide, a transient intermediary metabolite of Toltrazuril, undergoes in vivo metabolism to yield the reactive toltrazuril sulfone (TZR-SO2). Toltrazuril functions as an antiprotozoal agent targeting Coccidia parasites[1].
T35760	Carnaubadiol
	Carnaubadiol is a triterpene that has been found in E. corollata and has antiprotozoal activities.1,2 It is active against L. infantum promastigotes and amastigotes, as well as T. cruzi trypomastigotes (IC50s = 46.2, 7.8, and 14.9 μM, respectively).2 \|1. Piatak, D.M., and Reimann, K.A. Plant investigations IV. Corollatadiol A new triterpene from euphorbia corollata. Tetrahedron Lett. 13(44), 4525-4528 (1972).\|2. de Almeida, B.C., Araújo, B.Q., Carvalho, A.A., et al. Antiprotozoal activity of ext...
T25330	Difetarsone RP 4763,Diphetarson,RP4763,RP-4763,Difetarsonum
	Difetarsone is an antiprotozoal agent. Many studies have shown that it can be particularly effective against Trichuris trichiura, commonly known as the whipworm. It has also been used to treat Entamoeba histolytica infections.
T35905	Oasomycin B
	Oasomycin B is a bacterial metabolite that has been found inS. baldaciiand has antiprotozoal activity.1It is active againstT. vaginalis(MIC = 62.5 μg/ml). 1.Grabley, S., Kretzschmar, G., Mayer, M., et al.Secondary metabolites by chemical screening, 24. Oasomycins, new macrolactones of the desertomycin familyLiebigs Ann. Chem.5573-589(1993)
T24277	Hydroxy ipronidazole L-12407,Ipronidazole-OH,L12407,L 12407
	L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.
T6769	Elaiophylin 洋橄榄叶素,Efomycin E,Gopalamicin,Salbomycin,Azalomycin B	Others; Autophagy	Autophagy; Others
	Elaiophylin (Salbomycin) 是一种自噬抑制剂，在卵巢癌细胞中有抗肿瘤活性。它对 Plasmodium falciparum K1a 和 Trypanosoma brucei brucei GUTat 3.1 菌株具有抗原生动物活性，IC50 分别为 0.36 μM 和 0.45 μM。
T62520	Imidocarb dihydrochloride monohydrate
	Imidocarb dihydrochloride monohydrate 是一种有效的抗原虫剂，能够作用于寄生虫 B. bovis (IC50: 87 μg/ml)。
T63281	Antileishmanial agent-11
	Antileishmanial agent-11 是有效的抗利什曼原虫剂，能够作用于 Leishmania brazilensis (IC50: 28.3 μM)、Leishmania infantum (IC50: 24.8 μM) 和T. cruzi(IC50: 13.0 μM) 具有出抗原虫作用。
T79415	Antiparasitic agent-18	Parasite	Microbiology/Virology
	Antiparasitic agent-18 (compound 3a) 对T. brucei (EC50=0.4 μM)、T. cruzi (EC50=0.21 μM) 和 L. donovani (EC50=0.26 μM) 表现出高度的活性和选择性，证明其为一种有效的抗原虫化合物。
T62330	Antileishmanial agent-12
	Antileishmanial agent-12 (compound 5a) 是一种有效的抗利什曼原虫剂，对 Leishmania brazilensis (IC50: 14.9 μM)、Leishmania infantum (IC50: 21.3 μM) 和 T. cruzi (IC50: 9.3 μM) 具有抗原虫作用。
T63409	Teclozan
	Teclozan 是一种苄胺衍生物类的抗原虫剂。Teclozan 在肠腔中表现出抗 G. intestinalis 作用，能够干预磷脂代谢，阻止花生四烯酸的形成。Teclozan 能够用于研究原生动物感染。
T60465	Anti-infective agent 2
	Anti-infective agent 2 (化合物 3k) 是一种抗原生动物和抗分枝杆菌剂。Anti-infective agent 2对P. falciparum 和T. brucei rhodesiense 显示出抗寄生虫活性，IC50值分别为 0.07 和 2.20 μM。Anti-infective agent 2 对耻垢分枝杆菌显示出抗分支杆菌活性，其MIC 为 32 μg/mL。
T60468	Anti-infective agent 3
	Anti-infective agent 3 是一种抗原生动物和抗分枝杆菌剂。Anti-infective agent 3 (compound 3l) 对 P. falciparum 和 T. brucei rhodesiense 显示出抗寄生虫活性，IC50值分别为 0.47 和 0.13 μM。Anti-infective agent 3 对耻垢分枝杆菌显示出抗分支杆菌活性，MIC 值为 4 μg/mL。
T60315	Anti-infective agent 1
	Anti-infective agent 1 (化合物 3a) 是一种有效的、选择性的抗原生动物和抗结核分枝杆菌剂。Anti-infective agent 1 对P. falciparum 和T. brucei rhodesiense 具有抗寄生虫活性，IC50分别为 10.95 和 0.06 μM。Anti-infective agent 1 显示出对耻垢分枝杆菌的抗分支杆菌活性，MIC 为 8 μg/mL。
T71261	Arsthinol
	Arsthinol is an antiprotozoal agent which may have anti-cancer activity. It was found that arsthinol, a trivalent organoarsenic compound (dithiarsolane), has been active in vitro on leukemia cell lines and offers a better therapeutic index than arsenic trioxide, as estimated by the ratio LD50/IC50. Arsthinol induced growth inhibition of NB4 cells at lower concentration (IC50 (concentration inhibiting growth by 50%) = 0.78 +/- 0.08 micromol/l after 24 h) than As(2)O(3) (IC50 = 1.60 +/- 0.23 micro...

化合物

Toltrazuril (sulfone)

Cat.No: T5052

Synonym: Toltrazuril sulfone,妥曲珠利砜,Ponazuril

Target: Parasite

Cat.No: T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

Metronidazole acetic acid

Cat.No: T9233

Target: Antibacterial, Antibiotic, Parasite

Sulfaquinoxaline

Cat.No: T1177

Synonym: 磺胺喹恶啉,Avicocid,磺胺喹噁啉,Sulphaquinoxaline,Sulfabenzpyrazine

Target: Others, Antibacterial, Antibiotic, Parasite

Cat.No: T12223

Synonym: NF161,5-Nitro-2-furancarbaldehyde 2-ethyl semicarbazone,硝呋米腙,Etafurazone

Target: Antibiotic

Cat.No: T1647

Synonym: 洛硝哒唑,Ronidazol,罗硝唑,Ridzol

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T7121

Synonym: 磺胺氯吡嗪,Sulfachloropyrazine,Sulfachloropyrazine sodium,N-(5-氯-3-吡嗪基)-4-氨基苯磺酰胺

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T0751

Synonym: 呋喃唑酮,Furoxone

Target: Apoptosis, MAO, Antibacterial, Antibiotic

Cat.No: T4982

Synonym: 苄哒唑,苄硝唑,Radanil,Benznidazole,Ro 71051,Ro 07-1051

Target: Antibiotic, Parasite

Cat.No: T1061

Synonym: BAY-i 9142,Toltrazurilo,妥曲珠利,Baycox,Toltrazurilum,托曲珠利

Target: Antibiotic, Parasite

Cat.No: T1526

Synonym: NF 113,SAP 113,硝呋太尔,Methylmercadone

Target: Antibacterial, Antibiotic, Parasite

Cat.No: T4269

Synonym: 布帕伐醌,Butalex,BW 720C

Target: Antibiotic, Parasite

Cat.No: T1546

Synonym: NSC 697855,硝唑尼特

Target: Others, Influenza Virus, Parasite, Autophagy

Cat.No: T4218

Synonym: Brobenzoxaldine,溴沙定

Target: Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T5325

Synonym: 硝呋替莫,BAY-2502,BAY-A-2502

Target: Dehydrogenase, Parasite

Cat.No: T20535

Synonym: ME 108,NSC293873,NSC 293873,ME-108,NSC-293873,ME108

Target: Antibiotic, Parasite

Cat.No: T0701

Synonym: Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline,溴羟喹啉

Target: Antibiotic, Parasite

Pentamidine isethionate

Cat.No: T1654

Synonym: Pentamidine isethionate salt,Pentamidine diisethionate,喷他脒羟乙磺酸盐

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T23133

Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal

Cat.No: T0893

Synonym: 替硝唑,CP12574

Target: Antibacterial, Antibiotic

Cat.No: T17097

Target: Others

Levofuraltadone

Cat.No: T0896L

Synonym: Levofuraltadonum,NSC527986,NSC 527986,NSC-527986,NF-602

Antileishmanial agent-10

Cat.No: T62210

Isometamidium chloride

Cat.No: T19744

Synonym: A-4180,A4180,A 4180

Anti-Trypanosoma cruzi agent-3

Cat.No: T63869

Cat.No: T76257

Toltrazuril sulfoxide

Cat.No: T37639

Cat.No: T35760

Cat.No: T25330

Synonym: RP 4763,Diphetarson,RP4763,RP-4763,Difetarsonum

Cat.No: T35905

Hydroxy ipronidazole

Cat.No: T24277

Synonym: L-12407,Ipronidazole-OH,L12407,L 12407

Cat.No: T6769

Synonym: 洋橄榄叶素,Efomycin E,Gopalamicin,Salbomycin,Azalomycin B

Target: Others, Autophagy

Imidocarb dihydrochloride monohydrate

Cat.No: T62520

Antileishmanial agent-11

Cat.No: T63281

Antiparasitic agent-18

Cat.No: T79415

Target: Parasite

Antileishmanial agent-12

Cat.No: T62330

Cat.No: T63409

Anti-infective agent 2

Cat.No: T60465

Anti-infective agent 3

Cat.No: T60468

Anti-infective agent 1

Cat.No: T60315

Cat.No: T71261

Cat. No.	Product Name	Target	Signaling Pathways
T1079	Metronidazole Flagyl,Metronidazol,甲硝唑,Anagiardil	Apoptosis; NADPH; Hydrogenase; Antibacterial; Antibiotic; Parasite; Antifection	Apoptosis; Metabolism; Microbiology/Virology
	Metronidazole (Metronidazol) 是一种合成的硝基咪唑衍生物，具有抗原生动物和抗菌活性。
T7909	α-Terpinene 松油烯,α-松油烯	Others; Parasite; Antifungal	Microbiology/Virology; Others
	α-Terpinene 是存在于多种食品和芳香植物的精油中的一种单萜。它具有杀螨、抗真菌、抗氧化和抗原生动物特性，可研究锥虫病。
T1556	Ornidazole Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Ornidazole (Tiberal) 是一种5-硝基咪唑衍生物，能抗原生动物和厌氧菌。
T1033	Monensin sodium salt 莫能菌素钠盐,Sodium Monensin,Monensin A sodium salt	Sodium Channel; Antibacterial; Antibiotic	Membrane transporter/Ion channel; Microbiology/Virology
	Monensin sodium salt (Monensin A sodium salt) 是由肉桂链霉菌分泌的抗生素。它是一种介导Na+/H+交换的离子载体。它引起细胞多泡体 (MVBs) 增大并调节外泌体的分泌。
T1304	Chlortetracycline hydrochloride Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Chlortetracycline hydrochloride (Isphamycin) 是一种特异性钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。
TN6930	5-Desmethylsinensetin	Others	Others
	5-desmethylsinensetin 是分离自Stevia satureiifoliavar.satureiifolia 的天然产物，显示出抗原生动物的活性，抑制T. cruzi epimastigotes 和trypomastigotes 的IC50分别为 0.4 μg/mL 和75.1 μg/mL。
T2S1792	Lycobetaine 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐	Antibacterial	Microbiology/Virology
	Lycobetaine (Ungeremine) 是一种潜在的抗罗克福尔青霉和黑曲霉的生物杀菌剂。它对柱状黄杆菌有很强的抗菌活性。它有效地靶向哺乳动物以及细菌I 型和II 型拓扑异构酶。它显示出强烈的乙酰胆碱酯酶抑制活性（IC(50) 值为 0.35 microM）。它具有抗原生动物活性，在体外试验中对Trypanosoma brucei rhodesiense、T. cruzi 表现出良好的活性。
TN4933	Sahandol	Antifection	Microbiology/Virology
	Sahandol shows antiprotozoal activity against P. falciparum and T. brucei rhodesiense.
TN3177	6-Methyl-5,6-dihydropyran-2-one	Antifection	Microbiology/Virology
	6-Methyl-5,6-dihydropyran-2-on is bactericidal,and antiprotozoal agents.
T1033L	Monensin Elancoban,Rumensin,莫能菌素
	Monensin is an antiprotozoal agent produced by Streptomyces cinnamonensis. It has an inhibitory effect on the Wnt/β-catenin signaling cascade. Monensin is a prospective anticancer drug for the therapy of neoplasia with deregulated Wnt signaling.
T82716	cis-Melilotoside
	cis-Melilotoside, 一种 o-Coumaric acid 衍生物，显示出强大的抗氧化活性。该化合物针对T. cruzi表现出适度抗原生动物活性，IC50值为78.2 ug/mL。
T75575	Geranin A
	Geranin A 是一种 A 型原花青素，能够从雪老鹳草抗原生动物提取物中分离得到。
TN2798	20-Deoxocarnosol	ROS; Antifection	Immunology/Inflammation; Microbiology/Virology
	20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity.
T40643	Prodigiosin hydrochloride 盐酸灵菌红素,Prodigiosine hydrochloride
	Prodigiosin hydrochloride, a red pigment, is a bioactive secondary metabolite produced by bacteria. It exhibits potent proapoptotic activity and functions as an inhibitor of the Wnt/β-catenin pathway. Additionally, this compound possesses antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties.
T27564	Hymenidin	5-HT Receptor	GPCR/G Protein; Neuroscience
	Hymenidin是一种从冲绳海绵Hymeniacidon sp。中分离出的生物碱，是一种5-羟色胺能受体拮抗剂和电压门控钾通道抑制剂，具有潜在的抗原生动物作用，可选择性结合 FOXO1 DNA ，可降低去极化诱导的细胞钙升高。
TN3627	Chalepensin	ATPase; NADPH-oxidase; P450; Antifection	Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepensin shows antiprotozoal activity; it also can cause significant inhibition of radicle growth of A. hypochondriacus and E. crus-galli.
TN3276	8-Epixanthatin	Antifection	Microbiology/Virology
	8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O. cumana at nano- to micromolar concentrations. 8-Epixanthatin has antiprotozoal activity.
T72916	Justicidin B 爵床脂素B
	Justicidin B是一种高效的抗癌木脂素及促凋亡剂，同时具备显著的骨吸收抑制作用，并展现出强大的抗病毒、杀真菌和抗原虫能力。此外，Justicidin B能显着抑制血小板聚集。
T35758	Butyrolactone V
	Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM).2,1 Butyrolactone V (227 and 454.1 μM) is also active against adult S. mansoni worms.1 It scavenges 2,2-diphenyl-1-picrylhydrazyl and ABTS radicals with IC50 values of 20.7 and 3.7 μM, respectively, in cell-free assays.3 Butyrolactone V also...
T20636	Latrunculin B LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644	Antifungal	Microbiology/Virology
	Latrunculin B 是一种来自红海海绵的生物碱，是一种肌动蛋白聚合 (actin polymerization) 抑制剂，具有抗真菌和抗原生动物活性。Latrunculin B 调节肺静脉电生理特征并减轻牵张性心律失常的发生，可用于研究青少年青光眼。
T35751	Violacein
	Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserine lactone , a property that has been modified to create a strain of C. violaceum used in detecting quorum-sensing molecules.[3] Violacein is active against Gram-positive bacteria, including B. subtilis and S. aureus (MICs = 0.8 and 1.6 &#181M, respectively). It is also active aga...
TN4683	Nyasol	ERK; IL Receptor; IκB/IKK; NOS; NF-κB; Akt; Antifection	Cytoskeletal Signaling; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling
	Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly

天然产物

Cat.No: T1079

Synonym: Flagyl,Metronidazol,甲硝唑,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

Cat.No: T7909

Synonym: 松油烯,α-松油烯

Target: Others, Parasite, Antifungal

Cat.No: T1556

Synonym: Tiberal,Ornidazolum,NSC 95075,Ro 7-0207,奥硝唑

Target: Antibacterial, Antibiotic, Parasite

Monensin sodium salt

Cat.No: T1033

Synonym: 莫能菌素钠盐,Sodium Monensin,Monensin A sodium salt

Target: Sodium Channel, Antibacterial, Antibiotic

Chlortetracycline hydrochloride

Cat.No: T1304

Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素

Target: ribosome, Antibacterial, Antibiotic

5-Desmethylsinensetin

Cat.No: TN6930

Target: Others

Cat.No: T2S1792

Synonym: 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐

Target: Antibacterial

Cat.No: TN4933

Target: Antifection

6-Methyl-5,6-dihydropyran-2-one

Cat.No: TN3177

Target: Antifection

Cat.No: T1033L

Synonym: Elancoban,Rumensin,莫能菌素

cis-Melilotoside

Cat.No: T82716

Cat.No: T75575

20-Deoxocarnosol

Cat.No: TN2798

Target: ROS, Antifection

Prodigiosin hydrochloride

Cat.No: T40643

Synonym: 盐酸灵菌红素,Prodigiosine hydrochloride

Cat.No: T27564

Target: 5-HT Receptor

Cat.No: TN3627

Target: ATPase, NADPH-oxidase, P450, Antifection

Cat.No: TN3276

Target: Antifection

Cat.No: T72916

Synonym: 爵床脂素B

Butyrolactone V

Cat.No: T35758

Cat.No: T20636

Synonym: LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644

Target: Antifungal

Cat.No: T35751

Cat.No: TN4683

Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt, Antifection

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