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43

抑制剂 & 化合物

11

天然产物

1

化合物库

21

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Cat. No.	Product Name
L9860	抗抑郁症化合物库		1163 compounds
	1163 种与抑郁症相关的化合物，可以用于高通量和高内涵筛选

化合物库

抗抑郁症化合物库

Cat.No: L9860

Compounds: 1163

Cat. No.	Product Name	Target	Signaling Pathways
T81103	SSA antigenic peptide
	SSA antigenic peptide为Sjögren综合征相关抗原A(SSA)的成分，具有免疫活性的短肽链。
T78556	Antidepressant agent 5	Others	Others
	Antidepressant agent 5 是一种具有抗抑郁活性的 7-取代四氢异喹啉衍生物。Antidepressant agent 5 在研究抑郁症方面和木兰花碱作用效果类似，可用于预防和治疗抑郁症疾病。
T9293	SSAA09E3	SARS-CoV	Microbiology/Virology
	SSAA09E3 是一种新型 SARS-CoV 复制抑制剂，通过阻止病毒膜与宿主细胞膜融合而起作用。
T9109	SSAA09E2	RAAS; SARS-CoV	Endocrinology/Hormones; Microbiology/Virology
	SSAA09E2 是一种新型的SARS-CoV 复制抑制剂，通过阻断SARS-S 与SARS-CoV 受体血管紧张素转换酶-2 的早期相互作用发挥作用。
T60640	SSAO inhibitor-2
	SSAO inhibitor-2 (Compound 1) 可用于动脉粥样硬化、糖尿病及其并发症、肥胖、中风、慢性肾病、视网膜病变、慢性阻塞性肺病 (COPD)、自身免疫性疾病、多发性硬化等的研究。SSAO inhibitor-2 是氨基脲敏感性胺氧化酶 (SSAO) 抑制剂，其对人 SSAO 和 MAO-A 的IC50分别为 <10 nM 和 10-100 μM。
T125182	Assamsaponin A
	Assamsaponin A 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125182，CAS号为 259747-95-0。
T124925	Gaylussacin

T36942	SSAA09E1 SSAA09E1
	SSAA09E1 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) viral entry.1It reduces infection of HEK293T cells transiently transfected with angiotensin-converting enzyme 2 (ACE2) by an HIV-based virus system pseudotyped with SARS-CoV surface glycoprotein (EC50= 6.7 μM). SSAA09E1 also inhibits the proteolytic activity of cathepsin L (IC50= 5.33 μM) but not cathepsin B when used at a concentration of 20 μM. 1.()
T124374	4-O-Demethylmanassantin B
	4-O-Demethylmanassantin B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124374，CAS号为 695151-38-3。
T20773	Lissamine rhodamine B sulfonyl chloride
	Lissamine rhodamine B sulfonyl chloride is a fluorescent label used for forming stable conjugates with protein.
T125934	Amaranthussaponin I
	Amaranthussaponin I 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125934，CAS号为 139742-09-9。
T30757	Cassaine Nervocidine
	Cassaine is an erythrophleum alkaloid.
T124159	Heliocurassavicine
	Heliocurassavicine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124159。
T124154	Mussaenosidic acid
	Mussaenosidic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124154，CAS号为 82451-22-7。
T124866	Pyrochamissanthin
	Pyrochamissanthin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124866。
T125029	Massarilactone B
	Massarilactone B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125029，CAS号为 334022-96-7。
T125645	Mussaendoside S
	Mussaendoside S 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125645，CAS号为 165198-41-4。
T62495	Antidepressant agent 2
	Antidepressant agent 2 表现出明显的抗抑郁作用，其 MED 值为 0.1 mg/kg。
T124158	Heliocurassavinine
	Heliocurassavinine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124158。
T60909	SSAO inhibitor-3
	SSAO inhibitor-3 (Compound 2) 可用于研究动脉粥样硬化、糖尿病及其并发症、肥胖症、中风、慢性肾病、视网膜病变、慢性阻塞性肺病 (COPD)、自身免疫性疾病、多发性硬化等。SSAO inhibitor-3 是一种氨基脲敏感性胺氧化酶 (SSAO) 的抑制剂，对人 AOC1 和SSAO 的IC50分别为 0.1-10 μM 和 <10 nM 。
T75002	Antidepressant agent 3
	Antidepressant agent 3, 一种具有口服活性的抗抑郁剂，具备抗抑郁、抗焦虑、性能增强及促智活性。
T79791	Immunosuppressant-1	Apoptosis	Apoptosis
	Immunosuppressant-1（Compound 31）抑制抗-CD3/抗-CD28共刺激的T细胞增殖，具备免疫抑制活性。该化合物能激活活化的淋巴结细胞中的caspase-3和PARP，从而诱导细胞凋亡（apoptosis）。
T20771	Lissamine rhodamine B
	Lissamine rhodamine B, a new Radiotracer, is used for Imaging Tumors by Positron Emission Tomography.
T123894	4-O-Demethylmanassantin A
	4-O-Demethylmanassantin A 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123894，CAS号为 943011-47-0。
T61133	SSAO/VAP-1 inhibitor 1
	SSAO/VAP-1 inhibitor 1 是一种有效的SSAO/VAP-1抑制剂。SSAO/VAP-1 促进葡萄糖转运 4 (GLUT 4) 从脂肪细胞转移到细胞膜，从而调节葡萄糖转运。在内皮细胞中，SSAO/VAP-1 可以介导白细胞和内皮细胞的粘附和渗出，并参与炎症反应。SSAO/VAP-1 inhibitor 1 具有研究炎症和/或炎症相关疾病或糖尿病和/或糖尿病相关疾病的潜力。
T124023	6'-(p-Hydroxybenzoyl)mussaenosidic acid
	6'-(p-Hydroxybenzoyl)mussaenosidic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124023，CAS号为 87667-61-6。
T126009	Canadensissaponin 2
	Canadensissaponin 2 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126009，CAS号为 135236-46-3。
T126237	Cynoglossamine
	Cynoglossamine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126237。
T125932	Amaranthussaponin IV
	Amaranthussaponin IV 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125932，CAS号为 139742-12-4。
T75003	Antidepressant agent 4
	Antidepressant agent 4为一种口服活性抗抑郁剂，具备抗抑郁、抗焦虑、性能增强以及促智活性。
T82346	Galanin message associated peptide (1-41) amide
	Galanin message-associated peptide (1-41) amide 是肽类激素，结构由41个氨基酸残基组成，并以酰胺形式存在。
T32380	Kessane
	Kessane is a sesquiterpenoid oxide isolated from Japanese valerians.
T124410	Curassavine
	Curassavine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124410。
T125393	Melilotussaponin O1
	Melilotussaponin O1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125393，CAS号为 205441-52-7。
T35798	Massarigenin C
	Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 μM).2It is also an inhibitor of yeast α-glucosidase (IC50= 1.25 mM).1It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.
T125933	Amaranthussaponin II
	Amaranthussaponin II 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125933，CAS号为 139742-10-2。
T10332	Antidepressant agent 1	Others	Others
	Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. It also can be used to increase body temperature.
T126131	Assamicadine
	Assamicadine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126131。
T75585	Naja Mossambica Venom
	Naja Mossambica Venom (Mozambique Spitting Cobra Venom) 是一种蛇毒，可从 Naja Mossambica 获得。Naja Pallida Venom 对Candida 物种具有抗真菌活性。Naja Mossambica Venom 提取物 (如磷脂酶 A2) 可抑制钠钾 ATP 酶活性。
T125760	Dipsacussaponin C
	Dipsacussaponin C 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125760。
T39741	SSAO inhibitor-1
	SSAO inhibitor-1 is a compound that acts as an inhibitor of semicarbazide-sensitive amine oxidase (SSAO). It exhibits anti-inflammatory properties and is commonly employed in research pertaining to liver diseases.
T126211	Bellissaponin BS1
	Bellissaponin BS1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126211，CAS号为 121340-61-2。
T10936	D-I03 DI03	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	D-I03 是一种选择性的RAD52 抑制剂，Kd 为 25.8 µM。D-I03 抑制 RAD52 依赖性单链退火 (SSA) 和 D 环形成，IC50 分别为 5 µM 和 8 µM。D-I03 抑制 BRCA1 和 BRCA2 缺陷细胞的生长，并抑制顺铂诱导的 RAD52 病灶形成，但对 RAD51 无影响。

化合物

SSA antigenic peptide

Cat.No: T81103

Antidepressant agent 5

Cat.No: T78556

Target: Others

Cat.No: T9293

Target: SARS-CoV

Cat.No: T9109

Target: RAAS, SARS-CoV

SSAO inhibitor-2

Cat.No: T60640

Cat.No: T125182

Cat.No: T124925

Cat.No: T36942

Synonym: SSAA09E1

4-O-Demethylmanassantin B

Cat.No: T124374

Lissamine rhodamine B sulfonyl chloride

Cat.No: T20773

Amaranthussaponin I

Cat.No: T125934

Cat.No: T30757

Synonym: Nervocidine

Heliocurassavicine

Cat.No: T124159

Mussaenosidic acid

Cat.No: T124154

Pyrochamissanthin

Cat.No: T124866

Massarilactone B

Cat.No: T125029

Mussaendoside S

Cat.No: T125645

Antidepressant agent 2

Cat.No: T62495

Heliocurassavinine

Cat.No: T124158

SSAO inhibitor-3

Cat.No: T60909

Antidepressant agent 3

Cat.No: T75002

Immunosuppressant-1

Cat.No: T79791

Target: Apoptosis

Lissamine rhodamine B

Cat.No: T20771

4-O-Demethylmanassantin A

Cat.No: T123894

SSAO/VAP-1 inhibitor 1

Cat.No: T61133

6'-(p-Hydroxybenzoyl)mussaenosidic acid

Cat.No: T124023

Canadensissaponin 2

Cat.No: T126009

Cat.No: T126237

Amaranthussaponin IV

Cat.No: T125932

Antidepressant agent 4

Cat.No: T75003

Galanin message associated peptide (1-41) amide

Cat.No: T82346

Cat.No: T32380

Cat.No: T124410

Melilotussaponin O1

Cat.No: T125393

Cat.No: T35798

Amaranthussaponin II

Cat.No: T125933

Antidepressant agent 1

Cat.No: T10332

Target: Others

Cat.No: T126131

Naja Mossambica Venom

Cat.No: T75585

Dipsacussaponin C

Cat.No: T125760

SSAO inhibitor-1

Cat.No: T39741

Bellissaponin BS1

Cat.No: T126211

Cat.No: T10936

Synonym: DI03

Target: DNA/RNA Synthesis

Cat. No.	Product Name	Target	Signaling Pathways
TN4171	Grossamide	NO Synthase	Immunology/Inflammation
	Grossamide (GSE) 是一种来自虎杖的木脂酰胺。Grossamide 具有抗炎症活性，可通过上调精氨酸酶和下调诱导型一氧化氮合酶来抑制精氨酸产生一氧化氮(NO)，抑制NO对OXPHOS的抑制作用。
TN4489	Manassantin A	ERK; cAMP; TNF; NF-κB; MAPK; COX; HIF; Prostaglandin Receptor; JNK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; MAPK; Neuroscience; NF-κB; Stem Cells
	Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-ÎºB act
T75652	Molassamide B
	Molassamide B，丝氨酸蛋白酶抑制剂，对胰凝乳蛋白酶、弹性蛋白酶及蛋白酶 K 具有显著抑制活性，其IC50值分别为24.65、11.69和5.42 nM。
TN3717	Crassanine	Others	Others
	Crassanine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3717，CAS号为 16790-92-4。
TN6589	Grossamide K
	Grossamide K exerts a particularly strong anti-melanogenic activity on the cells without high cell toxicity.
TN4490	Manassantin B	ERK; BCL; p38 MAPK; TNF; NF-κB; JNK; STAT; Antifection	Apoptosis; JAK/STAT signaling; MAPK; Microbiology/Virology; NF-κB; Stem Cells
	Manassantin B is a potent inhibitor of NF-ÎºB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-ÎºB. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and activator of transcription 3 activation in Hep3B cells, it has potential as a potent anti-inflammatory drug for use in pathological processes such as sepsis or acute lung injury. Manassantin B exerts antifibrotic activity in HSC-T6 cells, in pa...
TN3065	4'-O-trans-p-Coumaroylmussaenoside	Others	Others
	4'-O-trans-p-Coumaroylmussaenoside是一种天然产物，属于马鞭草科紫珠属，其产品编号为 TN3065，CAS号为 1246012-27-0。4'-O-trans-p-Coumaroylmussaenoside可用作对照参考。
TN6087	Cassamedine
	Cassamedine 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6087，CAS号为 16408-75-6。
TN6511	Tessaric acid
	Tessaric acid has antifeedant and allelochemical effects. Tessaric acid derivatives induce G/M cell cycle arrest in human solid tumor cell lines.
T72732	Massarilactone H
	Massarilactone H 是一种聚酮化合物，是神经氨酸酶抑制剂，IC50值为 8.18 µM。
TN1960	Mussaenoside 玉叶金花甙酸甲酯	IL Receptor; TNF; NF-κB	Apoptosis; Immunology/Inflammation; NF-κB
	Mussaenoside has anti-inflammatory action, the mechanism associated with downregulation of nuclear factor-κB.

天然产物

Cat.No: TN4171

Target: NO Synthase

Cat.No: TN4489

Target: ERK, cAMP, TNF, NF-κB, MAPK, COX, HIF, Prostaglandin Receptor, JNK, STAT

Cat.No: T75652

Cat.No: TN3717

Target: Others

Cat.No: TN6589

Cat.No: TN4490

Target: ERK, BCL, p38 MAPK, TNF, NF-κB, JNK, STAT, Antifection

4'-O-trans-p-Coumaroylmussaenoside

Cat.No: TN3065

Target: Others

Cat.No: TN6087

Cat.No: TN6511

Massarilactone H

Cat.No: T72732

Cat.No: TN1960

Synonym: 玉叶金花甙酸甲酯

Target: IL Receptor, TNF, NF-κB

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05306	TRIM21 Protein, Human, Recombinant (His) Ro/SSA,SSA,RO52,RNF81,tripartite motif con...	Human	Baculovirus-Insect Cells
	TRIM21 Protein, Human, Recombinant (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 56.5 kDa. Accession number: P19474-1
TMPY-06327	Calreticulin Protein, Human, Recombinant HEL-S-99n,calreticulin,cC1qR,CRT,RO,SSA	Human	HEK293
	Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal. Located in storage compartments associated with the endoplasmic reticulum, calreticulin also binds to misfolded proteins and prevents them from being exported from the endoplasm...
TMPY-03259	Calreticulin Protein, Human, Recombinant (His) HEL-S-99n,cC1qR,SSA,CRT,RO,calreticulin	Human	HEK293
	Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal. Located in storage compartments associated with the endoplasmic reticulum, calreticulin also binds to misfolded proteins and prevents them from being exported from the endoplasm...
TMPY-03258	Calreticulin Protein, Human, Recombinant (hFc) RO,cC1qR,HEL-S-99n,CRT,calreticulin,SSA	Human	HEK293
	Calreticulin is a multifunctional protein. It acts as a main Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. Calreticulin binds Ca2+ ions (a second messenger in signal transduction), rendering it inactive. The Ca2+ is bound with low affinity, but high capacity, and can be released on a signal. Located in storage compartments associated with the endoplasmic reticulum, calreticulin also binds to misfolded proteins and prevents them from being exported from the endoplasm...
TMPH-03446	SSA1 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	May play a role in the transport of polypeptides both across the mitochondrial membranes and into the endoplasmic reticulum. A functional difference between SSA1 and SSA2 proteins is expected. SSA1 can participate in the ATP-dependent disassembly of clathrin-coated vesicles.
TMPH-03058	Cyanovirin-N homolog Protein, Neurospora crassa, Recombinant (His) Cyanovirin-N homolog,CV-N homolog	Neurospora crassa	E. coli
	Mannose-binding lectin.
TMPH-03057	Chorismate synthase Protein, Neurospora crassa, Recombinant (His) B7F21.10,NCU05420,aro-2,5-enolpyruvylshikimate-3-phosphate p...	Neurospora crassa	E. coli
	Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN.
TMPY-00048	Influenza B (B/Massachusetts/03/2010) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	Influenza B	Baculovirus-Insect Cells
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPY-00050	Influenza B (B/Massachusetts/03/2010) Hemagglutinin/HA0 Protein Harvey rat sarcoma viral oncogene homolog	Influenza B	Baculovirus-Insect Cells
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPH-02393	Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) GPC Protein (His & Myc)	LASV	E. coli
	interacts with the host receptor. Mediates virus attachment to host receptor alpha-dystroglycan DAG1. This attachment induces virion internalization predominantly through clathrin- and caveolin-independent endocytosis.; class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptid...
TMPH-03514	ClfA Protein, S. aureus (strain MSSA476), Recombinant (His & SUMO) Fibrinogen receptor A,Fibrinogen-binding protein A,clfA,Clum...	Staphylococcus aureus	E. coli
	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps.
TMPY-04247	Influenza B (B/Massachusetts/03/2010) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	Influenza B	HEK293
	The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host ...
TMPH-02391	Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein (His & SUMO)	LASV	E. coli
	Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon ac...
TMPH-02394	Lassa virus (strain GA391) GPC Protein (His & Myc)	LASV	E. coli
	class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation clea...
TMPH-03515	ClfA Protein, S. aureus (strain MSSA476), Recombinant clfA,Clumping factor A,Fibrinogen-binding protein A,Fibrinog...	Staphylococcus aureus	E. coli
	Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps.
TMPY-06666	Fra a 1 Protein, Fragaria Ananassa, Recombinant	Fragaria Ananassa	P. pastoris
	Fra a 1 Protein, Fragaria Ananassa, Recombinant is expressed in P. pastoris. The predicted molecular weight is 27.5 kDa.
TMPH-02392	Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein	LASV	E. coli
	Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon ac...
TMPH-02395	Lassa virus (strain GA391) GPC Protein (His)	LASV	in vitro E. coli expression system
	class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation clea...
TMPH-02396	Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Z Protein (His)	LASV	E. coli
	Plays a crucial role in virion assembly and budding. Expressed late in the virus life cycle, it acts as an inhibitor of viral transcription and RNA synthesis by interacting with the viral polymerase L. Presumably recruits the NP encapsidated genome to cellular membranes at budding sites via direct interaction with NP. Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins in...
TMPH-02632	TRIM21 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr...
TMPH-02633	TRIM21 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr...

重组蛋白

TRIM21 Protein, Human, Recombinant (His)

Cat.No: TMPY-05306

Species: Human

Expression System: Baculovirus-Insect Cells

Calreticulin Protein, Human, Recombinant

Cat.No: TMPY-06327

Species: Human

Expression System: HEK293

Calreticulin Protein, Human, Recombinant (His)

Cat.No: TMPY-03259

Species: Human

Expression System: HEK293

Calreticulin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-03258

Species: Human

Expression System: HEK293

SSA1 Protein, S. cerevisiae, Recombinant (His & Myc)

Cat.No: TMPH-03446

Species: Saccharomyces cerevisiae

Expression System: E. coli

Cyanovirin-N homolog Protein, Neurospora crassa, Recombinant (His)

Cat.No: TMPH-03058

Species: Neurospora crassa

Expression System: E. coli

Chorismate synthase Protein, Neurospora crassa, Recombinant (His)

Cat.No: TMPH-03057

Species: Neurospora crassa

Expression System: E. coli

Influenza B (B/Massachusetts/03/2010) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00048

Species: Influenza B

Expression System: Baculovirus-Insect Cells

Influenza B (B/Massachusetts/03/2010) Hemagglutinin/HA0 Protein

Cat.No: TMPY-00050

Species: Influenza B

Expression System: Baculovirus-Insect Cells

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) GPC Protein (His & Myc)

Cat.No: TMPH-02393

Species: LASV

Expression System: E. coli

ClfA Protein, S. aureus (strain MSSA476), Recombinant (His & SUMO)

Cat.No: TMPH-03514

Species: Staphylococcus aureus

Expression System: E. coli

Influenza B (B/Massachusetts/03/2010) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-04247

Species: Influenza B

Expression System: HEK293

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein (His & SUMO)

Cat.No: TMPH-02391

Species: LASV

Expression System: E. coli

Lassa virus (strain GA391) GPC Protein (His & Myc)

Cat.No: TMPH-02394

Species: LASV

Expression System: E. coli

ClfA Protein, S. aureus (strain MSSA476), Recombinant

Cat.No: TMPH-03515

Species: Staphylococcus aureus

Expression System: E. coli

Fra a 1 Protein, Fragaria Ananassa, Recombinant

Cat.No: TMPY-06666

Species: Fragaria Ananassa

Expression System: P. pastoris

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Nucleoprotein/NP Protein

Cat.No: TMPH-02392

Species: LASV

Expression System: E. coli

Lassa virus (strain GA391) GPC Protein (His)

Cat.No: TMPH-02395

Species: LASV

Expression System: in vitro E. coli expression system

Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) Z Protein (His)

Cat.No: TMPH-02396

Species: LASV

Expression System: E. coli

TRIM21 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02632

Species: Mouse

Expression System: E. coli

TRIM21 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02633

Species: Mouse

Expression System: Baculovirus

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