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Search Results for " mmp9 "

Targets Recommended: MMP

43

抑制剂 & 化合物

5

天然产物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T21512	MMP-2/MMP-9 Inhibitor I	MMP	Proteases/Proteasome
	MMP-2/MMP-9-IN-1 是一种有效的、具有高选择性和可口服的 IV 型胶原酶 (MMP-9和MMP-2) 抑制剂，对 MMP-9 和 MMP-2具有抑制作用， IC50分别为 0.24 和 0.3 1μM。MMP-2/MMP-9-IN-1 在肿瘤生长和转移的动物模型中展现出口服活性，可用于研究癌症。
T36712	BPHA MMP-2/MMP-9 Inhibitor II	MMP	Proteases/Proteasome
	BPHA (MMP-2/MMP-9 Inhibitor II) 是一种有效的、具有选择性和口服活性的抑制剂，对MMP-2、MMP-9 和 MMP-14 具有抑制作用，IC50 分别为 12 nM、16 nM 和 17 nM。BPHA 不抑制 MMP-1、-3 和 -7 (IC50 分别为 974、>1000 和 795 nM)。BPHA 具有抗血管生成和抗肿瘤活性。
T37726	MMP-9 Inhibitor I
	MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 μM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 μM.
T37172	MMP-9/MMP-13 Inhibitor I
	MMP-9/MMP-13 Inhibitor I 是 MMP-9 和 MMP-13 双重抑制剂，IC50 均为 0.9 nM。MMP-9/MMP-13 Inhibitor I 对 MMP-9/MMP-13 的选择性是其他 MMP 的 20 倍以上。
T7522	GI254023X GI 254023X	MMP; Immunology/Inflammation related	Immunology/Inflammation; Proteases/Proteasome
	GI254023X 是MMP9和ADAM10抑制剂，它们的IC50s 分别为 2.5 和 5.3 nM。
TP1545L1	FFAGLDD amine salt	Others	Others
	FFAGLDD amine salt 是MMP9选择性裂解肽，用于多柔比星（DOX）的胞浆递送，实现时间和空间可控的缓慢药物递送和释放。
T72069	MMP-9-IN-7
	MMP-9-IN-7抑制前基质金属蛋白酶活化,可用于预防、治疗或改善 MMP9和/或 MMP13介导的综合征。
T76856	Andecaliximab GS-5745	MMP; Virus Protease	Microbiology/Virology; Proteases/Proteasome
	Andecaliximab 是一种靶向基质金属蛋白酶 9 (MMP9) 的重组 IgG4 单克隆抗体。Andecaliximab 在特发性肺纤维化小鼠模型中显示出抗纤维化作用。Andecaliximab 可用于研究胃腺癌和特发性肺纤维化 (IPF) 以及登革热病毒。
T3560	Desmethylanethol trithione ADT-OH	VEGFR; Akt	Angiogenesis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	Desmethylanethol trithione (ADT-OH) 是合成硫化氢的供体。它利用上调 FADD 诱导细胞凋亡，并对体内黑色素瘤的形成具有一定的抑制作用，可用于研究癌症疾病。
T77617	MMP-9-IN-6	MMP	Proteases/Proteasome
	MMP-9-IN-6 是一种 MMP-9 抑制剂，其 IC50 值为50 μM, 具有较好的抗溃疡功效。MMP-9-IN-6 具有潜在的抗肿瘤活性，可用于研究组织重塑、伤口修复和动脉粥样硬化。
T10597	BR351	MMP	Proteases/Proteasome
	BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T4783	JNJ0966	MMP	Proteases/Proteasome
	JNJ0966 是高选择性 MMP-9酶原抑制剂，其 IC50=440 nM。
T10598	BR351 precursor	Others	Others
	BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T26720	AZD-6605 AZ11920155,AZ-11920155,AZD6605
	AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.
T26104	Ro 28-2653 Ro 28 2653,Ro-28-2653,Ro282653
	Ro 28-2653 is a matrix-metalloproteinases (MMPs) inhibitor with high selectivity for MMP2, MMP9 and membrane type 1-MMP.
TP1741L	Histatin 5 acetate Histatin 5 acetate (115966-68-2 Free base)	MMP	Proteases/Proteasome
	Histatin 5 acetate 抑制宿主基质金属蛋白酶 MMP-2 和 MMP-9 的活性，IC50 分别为 0.57 和 0.25 μM。
TP1545	FFAGLDD	Others	Others
	FFAGLDD 是 MMP9 选择性切割肽，用于多柔比星 (DOX) 的胞浆递送，实现时间和空间控制的缓慢药物递送和释放。
TP1498	FFAGLDD TFA
	FFAGLDD TFA is an MMP9 selective cleavage peptide, which is used for the cytoplasmic transfer of doxorubicin (DOX) to realize the controlled slow drug delivery and release.
T2009	SB-3CT	MMP	Proteases/Proteasome
	SB-3CT 是一种可透过血脑屏障的、竞争性的金属蛋白酶MMP-2和MMP-9抑制剂，Ki 分别为 13.9 nM、600 nM。他对明胶酶具有高选择性。它具有神经保护和抗癌作用。
T12539L	Prinomastat KB-R9896,普啉司他,AG3340	MMP	Proteases/Proteasome
	Prinomastat inhibits MMP-2, MMP-3 and MMP-9 (Kis: 0.05 nM, 0.3 nM and 0.26 nM, respectively). Prinomastat crosses the blood-brain barrier. It also has antitumor activity. Prinomastat is a broad-spectrum, potent, orally active metalloproteinase inhibitor (
T16124	MMP13-IN-3	MMP	Proteases/Proteasome
	MMP13-IN-3 是口服有效的MMP-13选择性抑制剂，IC50为 1 nM，比其他 MMP 的选择性高 1000倍多。MMP13-IN-3在用于骨关节炎方面有研究的价值。
T12414	PF-00356231 hydrochloride	MMP	Proteases/Proteasome
	PF-00356231 hydrochloride 是基质金属蛋白酶 MMP-12 的抑制剂，IC50 为 1.4 μM。
T6885	Marimastat BB2516,马立马司他,KB-R8898,TA2516	MMP	Proteases/Proteasome
	Marimastat (BB2516) 是一种血管生成和转移抑制剂，限制血管的生长和生成。它是一种广谱的，具有口服活性的MMPs 抑制剂，有效抑制 MMP-9 , MMP-1, MMP-2, MMP-14, MMP-7，用于癌症的研究。
T6011	Batimastat 巴马司他,BB94	MMP	Proteases/Proteasome
	Batimastat (BB94) 是广谱MMP 抑制剂，能够抑制MMP-1 (IC50:3 nM)，MMP-2 (IC50:4 nM)，MMP-9 (IC50:4 nM)，MMP-7 (IC50:6 nM) 和 MMP-3 (IC50:20 nM)。
T61271	MMP2-IN-3	MMP	Proteases/Proteasome
	MMP2-IN-3是一种有效的基质金属蛋白酶（MMP-2）抑制剂（ IC50 值：31 μM）。MMP2-IN-3 抑制 MMP-9 和 MMP-8 ，其 IC50 分别为 26.6 和 32 μM。
T14322	ARP-100 MMP-2 Inhibitor III	MMP	Proteases/Proteasome
	ARP-100 (MMP-2 Inhibitor III) 是选择性基质金属蛋白酶MMP-2抑制剂 (IC50=12 nM)。它对 MMP-1 (>50 μM)，MMP-3 (4.5 μM)，MMP-7 (>50 μM) 和MMP-9 (0.2 μM) 的抑制活性较小。它与 MMP-2 的 S1＇口袋相互作用，并在体外对基质胶的侵袭模型中显示抗侵袭特性。
T27654	JG26 JG 26,JG-26	MMP; Immunology/Inflammation related	Immunology/Inflammation; Proteases/Proteasome
	JG26 是一种强效的 ADAM17 抑制剂，对 ADAM8、ADAM17、ADAM10 和 MMP-12 均有抑制作用，其 IC50 值分别为 12 nM、1.9 nM、150 nM 和 9.4 nM，可用于研究机体免疫系统。
T20563	PD-166793 PD-166793-0000,PD 166793,PD166793	MMP	Proteases/Proteasome
	PD-166793是一种具有口服活性、有效性和选择性的 MMP 抑制剂，对 MMP-2，MMP-3 和 MMP-13 具有抑制作用。PD-166793 在大鼠心力衰竭模型中改善心肌缺血和再灌注损伤。
T2743	Ilomastat Galardin,GM6001,伊洛马司他	MMP	Proteases/Proteasome
	Ilomastat (GM6001) 是广谱的基质金属蛋白酶 (MMP) 抑制剂，可抑制 MMP 的活性，IC50值分别为 1.5 nM (MMP-1)，1.1 nM (MMP-2)，1.9 nM (MMP-3)，0.5 nM (MMP-9)，对人皮肤成纤维细胞胶原酶 (MMP-1) 的Ki=为 0.4 nM。
T12539	Prinomastat hydrochloride KB-R9896 hydrochloride,AG3340 hydrochloride	MMP	Proteases/Proteasome
	Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity.
T28146	ND-336 ND336,ND-336 hydrochloride,ND 336
	ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
T10461	Batimastat sodium salt BB-94 sodium salt	MMP	Proteases/Proteasome
	Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
T12082	MMP3 inhibitor 1	MMP	Proteases/Proteasome
	MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).
T16986	Tanomastat BAY 12-9566	MMP	Proteases/Proteasome
	Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively.
T17201	UK 356618	MMP	Proteases/Proteasome
	UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).
T38800	MMPI-1154
	MMPI-1154 is a highly promising imidazole-carboxylic acid (ICA) MMP-2 inhibitor (IC 50 = 6.6 μM) with excellent cardio-cytoprotective properties. It is specifically designed for the study of acute myocardial infarction. Additionally, MMPI-1154 exhibits significant inhibitory effects on MMP-13, MMP-1, and MMP-9 activities with IC 50 values of 1.8 μM, 10 μM, and 13 μM, respectively.
T13358	XL-784	MMP	Proteases/Proteasome
	XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T13357	XL-784 free base	Others	Others
	XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP), (IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T22685	CP-471474 CP 471474	Others	Others
	Broad spectrum MMP inhibitor (IC<sub>50</sub> values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice.
T13249	UK-370106	MMP	Proteases/Proteasome
	UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM).
T31063	CP-544439 UNII-516DO4KL5R
	CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.
T36492	CMC2.24
	CMC2.24 (TRB-N0224) is an orally active tricarbonylmethane agent that demonstrates effectiveness in inhibiting Ras activation and the downstream effector ERK1/2 pathway, thus effectively combating pancreatic tumor formation in mice. Additionally, CMC2.24 exerts potent inhibitory effects on zinc-dependent MMPs, with IC50s ranging from 2.0-69 μM. Furthermore, CMC2.24 aids in alleviating the progression of osteoarthritis by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis throug...
T28985	TMI-1 WAY-171318	Apoptosis; MMP	Apoptosis; Proteases/Proteasome
	TMI-1 (WAY-171318) 是一种有效的抑制剂，用于抑制去整合素金属酶17 (ADAM17) 和其他基质金属蛋白酶MMPs。TMI-1 能够有效地抑制LPS 诱导的人原代单核细胞和人全血中TNF-α的分泌。TMI-1 在三阴性 (TN) 和过度表达ERBB2的乳腺肿瘤细胞系中选择性地诱导Caspase 依赖的细胞凋亡。

化合物

MMP-2/MMP-9 Inhibitor I

Cat.No: T21512

Target: MMP

Cat.No: T36712

Synonym: MMP-2/MMP-9 Inhibitor II

Target: MMP

MMP-9 Inhibitor I

Cat.No: T37726

MMP-9/MMP-13 Inhibitor I

Cat.No: T37172

Cat.No: T7522

Synonym: GI 254023X

Target: MMP, Immunology/Inflammation related

FFAGLDD amine salt

Cat.No: TP1545L1

Target: Others

Cat.No: T72069

Cat.No: T76856

Synonym: GS-5745

Target: MMP, Virus Protease

Desmethylanethol trithione

Cat.No: T3560

Synonym: ADT-OH

Target: VEGFR, Akt

Cat.No: T77617

Target: MMP

Cat.No: T10597

Target: MMP

Cat.No: T4783

Target: MMP

BR351 precursor

Cat.No: T10598

Target: Others

Cat.No: T26720

Synonym: AZ11920155,AZ-11920155,AZD6605

Cat.No: T26104

Synonym: Ro 28 2653,Ro-28-2653,Ro282653

Histatin 5 acetate

Cat.No: TP1741L

Synonym: Histatin 5 acetate (115966-68-2 Free base)

Target: MMP

Cat.No: TP1545

Target: Others

Cat.No: TP1498

Cat.No: T2009

Target: MMP

Cat.No: T12539L

Synonym: KB-R9896,普啉司他,AG3340

Target: MMP

Cat.No: T16124

Target: MMP

PF-00356231 hydrochloride

Cat.No: T12414

Target: MMP

Cat.No: T6885

Synonym: BB2516,马立马司他,KB-R8898,TA2516

Target: MMP

Cat.No: T6011

Synonym: 巴马司他,BB94

Target: MMP

Cat.No: T61271

Target: MMP

Cat.No: T14322

Synonym: MMP-2 Inhibitor III

Target: MMP

Cat.No: T27654

Synonym: JG 26,JG-26

Target: MMP, Immunology/Inflammation related

Cat.No: T20563

Synonym: PD-166793-0000,PD 166793,PD166793

Target: MMP

Cat.No: T2743

Synonym: Galardin,GM6001,伊洛马司他

Target: MMP

Prinomastat hydrochloride

Cat.No: T12539

Synonym: KB-R9896 hydrochloride,AG3340 hydrochloride

Target: MMP

Cat.No: T28146

Synonym: ND336,ND-336 hydrochloride,ND 336

Batimastat sodium salt

Cat.No: T10461

Synonym: BB-94 sodium salt

Target: MMP

MMP3 inhibitor 1

Cat.No: T12082

Target: MMP

Cat.No: T16986

Synonym: BAY 12-9566

Target: MMP

Cat.No: T17201

Target: MMP

Cat.No: T38800

Cat.No: T13358

Target: MMP

XL-784 free base

Cat.No: T13357

Target: Others

Cat.No: T22685

Synonym: CP 471474

Target: Others

Cat.No: T13249

Target: MMP

Cat.No: T31063

Synonym: UNII-516DO4KL5R

Cat.No: T36492

Cat.No: T28985

Synonym: WAY-171318

Target: Apoptosis, MMP

Cat. No.	Product Name	Target	Signaling Pathways
T3860	Isoliquiritin apioside	MMP; p38 MAPK; NF-κB	MAPK; NF-κB; Proteases/Proteasome
	Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成，显著降低 PMA 诱导的MMP9活性增加，并抑制 PMA 诱导的MAPK 和NF-κB 活化。
T3414	Morroniside 莫诺苷,奎宁树	Apoptosis; MMP; Pyroptosis	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T4S21320	ISOGINKGETIN 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮	MMP; Others	Others; Proteases/Proteasome
	ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂，也是一种Pre-mRNA Splicing 抑制剂。
T3850	Luteolin 7-O-glucuronide Luteolin-7-glucuronide,木犀草素-7-O-葡萄糖醛酸苷	MMP	Proteases/Proteasome
	Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) 是一种自由基清除剂，能够抑制基质金属蛋白酶的活性，其对 MMP-1，MMP-3，MMP-8，MMP-9，MMP-13的IC50值分别为 17.63，7.99，11.42，12.85，0.03 μM。
T5S1026	Apigenin-7-glucuronide Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸	MMP	Proteases/Proteasome
	Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) 能够抑制基质金属蛋白酶的活性，其对 MMP-3 (IC50:12.87 μM)，MMP-8 (IC50:22.39 μM)，MMP-9 (IC50:17.52 μM)，MMP-13 (IC50:0.27 μM)。

天然产物

Isoliquiritin apioside

Cat.No: T3860

Target: MMP, p38 MAPK, NF-κB

Cat.No: T3414

Synonym: 莫诺苷,奎宁树

Target: Apoptosis, MMP, Pyroptosis

Cat.No: T4S21320

Synonym: 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮

Target: MMP, Others

Luteolin 7-O-glucuronide

Cat.No: T3850

Synonym: Luteolin-7-glucuronide,木犀草素-7-O-葡萄糖醛酸苷

Target: MMP

Apigenin-7-glucuronide

Cat.No: T5S1026

Synonym: Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸

Target: MMP

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01919	MMP-9 Protein, Mouse, Recombinant matrix metallopeptidase 9,Clg4b,MMP-9<...	Mouse	HEK293 Cells
	MMP-9 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 78.4 kDa and the accession number is P41245-1.
TMPY-01248	MMP-9 Protein, Human, Recombinant MANDP2,MMP-9,GELB,matrix metallopeptidase ...	Human	HEK293 Cells
	MMP-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.3 kDa and the accession number is P14780.
TMPY-00888	MMP-9 Protein, Human, Recombinant (His) MANDP2,CLG4B,GELB,matrix metallopeptidase 9,MMP...	Human	HEK293 Cells
	MMP-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.7 kDa and the accession number is P14780.
TMPK-00368	MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated Gelatinase B,MMP-9,MANDP2,CLG4B,GELB	Human	HEK293 Cells
	Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina...
TMPK-00503	MMP-9 Protein, Cynomolgus, Recombinant (His) MMP-9,CLG4B,Gelatinase B,MANDP2,GELB	Cynomolgus	HEK293 Cells
	Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Cynomolgus, Reco...
TMPK-00367	MMP-9 Protein, Human, Recombinant (His & Avi) MANDP2,CLG4B,Gelatinase B,GELB,MMP-9	Human	HEK293 Cells
	Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina...
TMPJ-00957	MMP-9 Protein, Mouse, Recombinant (His) Matrix metalloproteinase-9,92 kDa gelatina...	Mouse	HEK293 Cells
	Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by ker...
TMPK-00946	EFEMP1 Protein, Human, Recombinant (His) MLVT,S1-5,Fibulin 3,FBNL,fibrillin-like,MGC111353,FBLN3,FBNL...	Human	HEK293 Cells
	Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9; TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion. EFEMP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His ...
TMPK-01082	EFEMP1 Protein, Mouse, Recombinant (His) EFEMP1,MTLV,MGC111353,MLVT,S1-5,DHRD,FBNLFLJ35535,fibrillin-...	Mouse	HEK293 Cells
	Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9; TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion. EFEMP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His ...
TMPH-01316	ECM1 Protein, Human, Recombinant (GST & His & Myc) Extracellular matrix protein 1,ECM1,Secretory component p85	Human	E. coli
	Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. ECM1 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q16610.
TMPK-01034	SEMA4B Protein, Mouse, Recombinant (His) SEMA4B,SemC,Semaphorin-C,MGC131831,Semaphorin-4B,KIAA1745,SE...	Mouse	HEK293 Cells
	Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.
TMPH-01297	DDR1 Protein, Human, Recombinant (aa 21-417, His) EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...	Human	HEK293 Cells
	Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell...
TMPY-02689	MMP-3 Protein, Human, Recombinant STMY,MMP-3,matrix metallopeptidase 3,CHDS6,STMY1,SL...	Human	E. coli
	Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This prot...

重组蛋白

MMP-9 Protein, Mouse, Recombinant

Cat.No: TMPY-01919

Species: Mouse

Expression System: HEK293 Cells

MMP-9 Protein, Human, Recombinant

Cat.No: TMPY-01248

Species: Human

Expression System: HEK293 Cells

MMP-9 Protein, Human, Recombinant (His)

Cat.No: TMPY-00888

Species: Human

Expression System: HEK293 Cells

MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00368

Species: Human

Expression System: HEK293 Cells

MMP-9 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00503

Species: Cynomolgus

Expression System: HEK293 Cells

MMP-9 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00367

Species: Human

Expression System: HEK293 Cells

MMP-9 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00957

Species: Mouse

Expression System: HEK293 Cells

EFEMP1 Protein, Human, Recombinant (His)

Cat.No: TMPK-00946

Species: Human

Expression System: HEK293 Cells

EFEMP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01082

Species: Mouse

Expression System: HEK293 Cells

ECM1 Protein, Human, Recombinant (GST & His & Myc)

Cat.No: TMPH-01316

Species: Human

Expression System: E. coli

SEMA4B Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01034

Species: Mouse

Expression System: HEK293 Cells

DDR1 Protein, Human, Recombinant (aa 21-417, His)

Cat.No: TMPH-01297

Species: Human

Expression System: HEK293 Cells

MMP-3 Protein, Human, Recombinant

Cat.No: TMPY-02689

Species: Human

Expression System: E. coli

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