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Search Results for " mmp9 "
Targets Recommended: MMP

43

抑制剂 & 化合物

5

天然产物

13

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T21512 MMP-2/MMP-9 Inhibitor I

MMP Proteases/Proteasome
MMP-2/MMP-9-IN-1 是一种有效的、具有高选择性和可口服的 IV 型胶原酶 (MMP-9MMP-2) 抑制剂,对 MMP-9MMP-2具有抑制作用, IC50分别为 0.24 和 0.3 1μM。MMP-2/MMP-9-IN-1 在肿瘤生长和转移的动物模型中展现出口服活性,可用于研究癌症。
T36712 BPHA

MMP-2/MMP-9 Inhibitor II

MMP Proteases/Proteasome
BPHA (MMP-2/MMP-9 Inhibitor II) 是一种有效的、具有选择性和口服活性的抑制剂,对MMP-2、MMP-9MMP-14 具有抑制作用,IC50 分别为 12 nM、16 nM 和 17 nM。BPHA 不抑制 MMP-1、-3 和 -7 (IC50 分别为 974、>1000 和 795 nM)。BPHA 具有抗血管生成和抗肿瘤活性。
T37726 MMP-9 Inhibitor I

MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TACE) in a dose-dependent manner (IC50 = 0.54 μM). MMP-9 inhibitor I decreases TNF-α secretion stimulated by LPS in BV-2 microglial cells when used at concentrations of 50 and 100 μM.
T37172 MMP-9/MMP-13 Inhibitor I

MMP-9/MMP-13 Inhibitor I 是 MMP-9MMP-13 双重抑制剂,IC50 均为 0.9 nM。MMP-9/MMP-13 Inhibitor I 对 MMP-9/MMP-13 的选择性是其他 MMP 的 20 倍以上。
T7522 GI254023X

GI 254023X

MMP; Immunology/Inflammation related Immunology/Inflammation; Proteases/Proteasome
GI254023X 是MMP9和ADAM10抑制剂,它们的IC50s 分别为 2.5 和 5.3 nM。
TP1545L1 FFAGLDD amine salt

Others Others
FFAGLDD amine salt 是MMP9选择性裂解肽,用于多柔比星(DOX)的胞浆递送,实现时间和空间可控的缓慢药物递送和释放。
T72069 MMP-9-IN-7

MMP-9-IN-7抑制前基质金属蛋白酶活化,可用于预防、治疗或改善 MMP9和/或 MMP13介导的综合征。
T76856 Andecaliximab

GS-5745

MMP; Virus Protease Microbiology/Virology; Proteases/Proteasome
Andecaliximab 是一种靶向基质金属蛋白酶 9 (MMP9) 的重组 IgG4 单克隆抗体。Andecaliximab 在特发性肺纤维化小鼠模型中显示出抗纤维化作用。Andecaliximab 可用于研究胃腺癌和特发性肺纤维化 (IPF) 以及登革热病毒。
T3560 Desmethylanethol trithione

ADT-OH

VEGFR; Akt Angiogenesis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
Desmethylanethol trithione (ADT-OH) 是合成硫化氢的供体。它利用上调 FADD 诱导细胞凋亡,并对体内黑色素瘤的形成具有一定的抑制作用,可用于研究癌症疾病。
T77617 MMP-9-IN-6

MMP Proteases/Proteasome
MMP-9-IN-6 是一种 MMP-9 抑制剂,其 IC50 值为50 μM, 具有较好的抗溃疡功效。MMP-9-IN-6 具有潜在的抗肿瘤活性,可用于研究组织重塑、伤口修复和动脉粥样硬化。
T10597 BR351

MMP Proteases/Proteasome
BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T4783 JNJ0966

MMP Proteases/Proteasome
JNJ0966 是高选择性 MMP-9酶原抑制剂,其 IC50=440 nM。
T10598 BR351 precursor

Others Others
BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor (IC50s: 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13).
T26720 AZD-6605

AZ11920155,AZ-11920155,AZD6605

AZD6605 is a potent, reversible inhibitor of, MMP2, MMP9, MMP12 and MMP13.
T26104 Ro 28-2653

Ro 28 2653,Ro-28-2653,Ro282653

Ro 28-2653 is a matrix-metalloproteinases (MMPs) inhibitor with high selectivity for MMP2, MMP9 and membrane type 1-MMP.
TP1741L Histatin 5 acetate

Histatin 5 acetate (115966-68-2 Free base)

MMP Proteases/Proteasome
Histatin 5 acetate 抑制宿主基质金属蛋白酶 MMP-2 和 MMP-9 的活性,IC50 分别为 0.57 和 0.25 μM。
TP1545 FFAGLDD

Others Others
FFAGLDD 是 MMP9 选择性切割肽,用于多柔比星 (DOX) 的胞浆递送,实现时间和空间控制的缓慢药物递送和释放。
TP1498 FFAGLDD TFA

FFAGLDD TFA is an MMP9 selective cleavage peptide, which is used for the cytoplasmic transfer of doxorubicin (DOX) to realize the controlled slow drug delivery and release.
T2009 SB-3CT

MMP Proteases/Proteasome
SB-3CT 是一种可透过血脑屏障的、竞争性的金属蛋白酶MMP-2和MMP-9抑制剂,Ki 分别为 13.9 nM、600 nM。他对明胶酶具有高选择性。它具有神经保护和抗癌作用。
T16124 MMP13-IN-3

MMP Proteases/Proteasome
MMP13-IN-3 是口服有效的MMP-13选择性抑制剂,IC50为 1 nM,比其他 MMP 的选择性高 1000倍多。MMP13-IN-3在用于骨关节炎方面有研究的价值。
T27654 JG26

JG 26,JG-26

MMP; Immunology/Inflammation related Immunology/Inflammation; Proteases/Proteasome
JG26 是一种强效的 ADAM17 抑制剂,对 ADAM8、ADAM17、ADAM10 和 MMP-12 均有抑制作用,其 IC50 值分别为 12 nM、1.9 nM、150 nM 和 9.4 nM,可用于研究机体免疫系统。
T61271 MMP2-IN-3

MMP Proteases/Proteasome
MMP2-IN-3是一种有效的基质金属蛋白酶(MMP-2)抑制剂( IC50 值:31 μM)。MMP2-IN-3 抑制 MMP-9MMP-8 ,其 IC50 分别为 26.6 和 32 μM。
T14322 ARP-100

MMP-2 Inhibitor III

MMP Proteases/Proteasome
ARP-100 (MMP-2 Inhibitor III) 是选择性基质金属蛋白酶MMP-2抑制剂 (IC50=12 nM)。它对 MMP-1 (>50 μM),MMP-3 (4.5 μM),MMP-7 (>50 μM) 和MMP-9 (0.2 μM) 的抑制活性较小。它与 MMP-2 的 S1'口袋相互作用,并在体外对基质胶的侵袭模型中显示抗侵袭特性。
T12414 PF-00356231 hydrochloride

MMP Proteases/Proteasome
PF-00356231 hydrochloride 是基质金属蛋白酶 MMP-12 的抑制剂,IC50 为 1.4 μM。
T6885 Marimastat

BB2516,马立马司他,KB-R8898,TA2516

MMP Proteases/Proteasome
Marimastat (BB2516) 是一种血管生成和转移抑制剂,限制血管的生长和生成。它是一种广谱的,具有口服活性的MMPs 抑制剂,有效抑制 MMP-9 , MMP-1, MMP-2, MMP-14, MMP-7,用于癌症的研究。
T6011 Batimastat

巴马司他,BB94

MMP Proteases/Proteasome
Batimastat (BB94) 是广谱MMP 抑制剂,能够抑制MMP-1 (IC50:3 nM),MMP-2 (IC50:4 nM),MMP-9 (IC50:4 nM),MMP-7 (IC50:6 nM) 和 MMP-3 (IC50:20 nM)。
T20563 PD-166793

PD-166793-0000,PD 166793,PD166793

MMP Proteases/Proteasome
PD-166793是一种具有口服活性、有效性和选择性的 MMP 抑制剂,对 MMP-2,MMP-3 和 MMP-13 具有抑制作用。PD-166793 在大鼠心力衰竭模型中改善心肌缺血和再灌注损伤。
T2743 Ilomastat

Galardin,GM6001,伊洛马司他

MMP Proteases/Proteasome
Ilomastat (GM6001) 是广谱的基质金属蛋白酶 (MMP) 抑制剂,可抑制 MMP 的活性,IC50值分别为 1.5 nM (MMP-1),1.1 nM (MMP-2),1.9 nM (MMP-3),0.5 nM (MMP-9),对人皮肤成纤维细胞胶原酶 (MMP-1) 的Ki=为 0.4 nM。
T12539 Prinomastat hydrochloride

KB-R9896 hydrochloride,AG3340 hydrochloride

MMP Proteases/Proteasome
Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity.
T12539L Prinomastat

KB-R9896,普啉司他,AG3340

MMP Proteases/Proteasome
Prinomastat inhibits MMP-2, MMP-3 and MMP-9 (Kis: 0.05 nM, 0.3 nM and 0.26 nM, respectively). Prinomastat crosses the blood-brain barrier. It also has antitumor activity. Prinomastat is a broad-spectrum, potent, orally active metalloproteinase inhibitor (
T28146 ND-336

ND336,ND-336 hydrochloride,ND 336

ND-336 is a highly selective inhibitor ofMMP-2, MMP-9 and MMP-14. ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.
T10461 Batimastat sodium salt

BB-94 sodium salt

MMP Proteases/Proteasome
Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
T12082 MMP3 inhibitor 1

MMP Proteases/Proteasome
MMP3 inhibitor 1 is a potent and highly selective inhibitor of MMP-3 (IC50 of 1 nM).
T16986 Tanomastat

BAY 12-9566

MMP Proteases/Proteasome
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively.
T38800 MMPI-1154

MMPI-1154 is a highly promising imidazole-carboxylic acid (ICA) MMP-2 inhibitor (IC 50 = 6.6 μM) with excellent cardio-cytoprotective properties. It is specifically designed for the study of acute myocardial infarction. Additionally, MMPI-1154 exhibits significant inhibitory effects on MMP-13, MMP-1, and MMP-9 activities with IC 50 values of 1.8 μM, 10 μM, and 13 μM, respectively.
T17201 UK 356618

MMP Proteases/Proteasome
UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).
T13358 XL-784

MMP Proteases/Proteasome
XL-784 is a selective inhibitor of matrix metalloproteinases (MMP)(IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T13357 XL-784 free base

Others Others
XL-784 free base is a selective inhibitor of matrix metalloproteinases (MMP), (IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1,MMP-2,MMP-3,MMP-8,MMP-9,MMP-13,respectively).
T22685 CP-471474

CP 471474

Others Others
Broad spectrum MMP inhibitor (IC<sub>50</sub> values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Attenuates early left ventricular dilation after experimental myocardial infarction in mice.
T13249 UK-370106

MMP Proteases/Proteasome
UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM).
T31063 CP-544439

UNII-516DO4KL5R

CP-544439 is an inhibitor of matrix metalloproteinase-13, which has an effect on adipose tissue development.
T36492 CMC2.24

CMC2.24 (TRB-N0224) is an orally active tricarbonylmethane agent that demonstrates effectiveness in inhibiting Ras activation and the downstream effector ERK1/2 pathway, thus effectively combating pancreatic tumor formation in mice. Additionally, CMC2.24 exerts potent inhibitory effects on zinc-dependent MMPs, with IC50s ranging from 2.0-69 μM. Furthermore, CMC2.24 aids in alleviating the progression of osteoarthritis by restoring cartilage homeostasis and inhibiting chondrocyte apoptosis throug...
T28985 TMI-1

WAY-171318

Apoptosis; MMP Apoptosis; Proteases/Proteasome
TMI-1 (WAY-171318) 是一种有效的抑制剂,用于抑制去整合素金属酶17 (ADAM17) 和其他基质金属蛋白酶MMPs。TMI-1 能够有效地抑制LPS 诱导的人原代单核细胞和人全血中TNF-α的分泌。TMI-1 在三阴性 (TN) 和过度表达ERBB2的乳腺肿瘤细胞系中选择性地诱导Caspase 依赖的细胞凋亡。

化合物

MMP-2/MMP-9 Inhibitor I
Cat.No: T21512
Synonym:
Target: MMP
BPHA
Cat.No: T36712
Synonym: MMP-2/MMP-9 Inhibitor II
Target: MMP
MMP-9 Inhibitor I
Cat.No: T37726
Synonym:
Target:
MMP-9/MMP-13 Inhibitor I
Cat.No: T37172
Synonym:
Target:
GI254023X
Cat.No: T7522
Synonym: GI 254023X
Target: MMP, Immunology/Inflammation related
FFAGLDD amine salt
Cat.No: TP1545L1
Synonym:
Target: Others
MMP-9-IN-7
Cat.No: T72069
Synonym:
Target:
Andecaliximab
Cat.No: T76856
Synonym: GS-5745
Target: MMP, Virus Protease
Desmethylanethol trithione
Cat.No: T3560
Synonym: ADT-OH
Target: VEGFR, Akt
MMP-9-IN-6
Cat.No: T77617
Synonym:
Target: MMP
BR351
Cat.No: T10597
Synonym:
Target: MMP
JNJ0966
Cat.No: T4783
Synonym:
Target: MMP
BR351 precursor
Cat.No: T10598
Synonym:
Target: Others
AZD-6605
Cat.No: T26720
Synonym: AZ11920155,AZ-11920155,AZD6605
Target:
Ro 28-2653
Cat.No: T26104
Synonym: Ro 28 2653,Ro-28-2653,Ro282653
Target:
Histatin 5 acetate
Cat.No: TP1741L
Synonym: Histatin 5 acetate (115966-68-2 Free base)
Target: MMP
FFAGLDD
Cat.No: TP1545
Synonym:
Target: Others
FFAGLDD TFA
Cat.No: TP1498
Synonym:
Target:
SB-3CT
Cat.No: T2009
Synonym:
Target: MMP
MMP13-IN-3
Cat.No: T16124
Synonym:
Target: MMP
JG26
Cat.No: T27654
Synonym: JG 26,JG-26
Target: MMP, Immunology/Inflammation related
MMP2-IN-3
Cat.No: T61271
Synonym:
Target: MMP
ARP-100
Cat.No: T14322
Synonym: MMP-2 Inhibitor III
Target: MMP
PF-00356231 hydrochloride
Cat.No: T12414
Synonym:
Target: MMP
Marimastat
Cat.No: T6885
Synonym: BB2516,马立马司他,KB-R8898,TA2516
Target: MMP
Batimastat
Cat.No: T6011
Synonym: 巴马司他,BB94
Target: MMP
PD-166793
Cat.No: T20563
Synonym: PD-166793-0000,PD 166793,PD166793
Target: MMP
Ilomastat
Cat.No: T2743
Synonym: Galardin,GM6001,伊洛马司他
Target: MMP
Prinomastat hydrochloride
Cat.No: T12539
Synonym: KB-R9896 hydrochloride,AG3340 hydrochloride
Target: MMP
Prinomastat
Cat.No: T12539L
Synonym: KB-R9896,普啉司他,AG3340
Target: MMP
ND-336
Cat.No: T28146
Synonym: ND336,ND-336 hydrochloride,ND 336
Target:
Batimastat sodium salt
Cat.No: T10461
Synonym: BB-94 sodium salt
Target: MMP
MMP3 inhibitor 1
Cat.No: T12082
Synonym:
Target: MMP
Tanomastat
Cat.No: T16986
Synonym: BAY 12-9566
Target: MMP
MMPI-1154
Cat.No: T38800
Synonym:
Target:
UK 356618
Cat.No: T17201
Synonym:
Target: MMP
XL-784
Cat.No: T13358
Synonym:
Target: MMP
XL-784 free base
Cat.No: T13357
Synonym:
Target: Others
CP-471474
Cat.No: T22685
Synonym: CP 471474
Target: Others
UK-370106
Cat.No: T13249
Synonym:
Target: MMP
CP-544439
Cat.No: T31063
Synonym: UNII-516DO4KL5R
Target:
CMC2.24
Cat.No: T36492
Synonym:
Target:
TMI-1
Cat.No: T28985
Synonym: WAY-171318
Target: Apoptosis, MMP
Cat. No. Product Name Target Signaling Pathways
T3860 Isoliquiritin apioside

MMP; p38 MAPK; NF-κB MAPK; NF-κB; Proteases/Proteasome
Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成,显著降低 PMA 诱导的MMP9活性增加,并抑制 PMA 诱导的MAPK 和NF-κB 活化。
T3414 Morroniside

莫诺苷,奎宁树

Apoptosis; MMP; Pyroptosis Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T4S21320 ISOGINKGETIN

异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮

MMP; Others Others; Proteases/Proteasome
ISOGINKGETIN (4',4'''-Dimethylamentoflavone) 是一种MMP9抑制剂,也是一种Pre-mRNA Splicing 抑制剂。
T3850 Luteolin 7-O-glucuronide

Luteolin-7-glucuronide,木犀草素-7-O-葡萄糖醛酸苷

MMP Proteases/Proteasome
Luteolin 7-O-glucuronide (Luteolin-7-glucuronide) 是一种自由基清除剂,能够抑制基质金属蛋白酶的活性,其对 MMP-1,MMP-3,MMP-8,MMP-9MMP-13的IC50值分别为 17.63,7.99,11.42,12.85,0.03 μM。
T5S1026 Apigenin-7-glucuronide

Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸

MMP Proteases/Proteasome
Apigenin-7-glucuronide (Apigenin 7-O-glucuronide) 能够抑制基质金属蛋白酶的活性,其对 MMP-3 (IC50:12.87 μM),MMP-8 (IC50:22.39 μM),MMP-9 (IC50:17.52 μM),MMP-13 (IC50:0.27 μM)。

天然产物

Isoliquiritin apioside
Cat.No: T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
Morroniside
Cat.No: T3414
Synonym: 莫诺苷,奎宁树
Target: Apoptosis, MMP, Pyroptosis
ISOGINKGETIN
Cat.No: T4S21320
Synonym: 异银杏素,4',4'''-Dimethylamentoflavone,异银杏双黄酮
Target: MMP, Others
Luteolin 7-O-glucuronide
Cat.No: T3850
Synonym: Luteolin-7-glucuronide,木犀草素-7-O-葡萄糖醛酸苷
Target: MMP
Apigenin-7-glucuronide
Cat.No: T5S1026
Synonym: Apigenin 7-O-glucuronide,芹菜素-7-葡萄糖醛酸
Target: MMP
Cat. No. Product Name Species Expression System
TMPY-01919 MMP-9 Protein, Mouse, Recombinant

matrix metallopeptidase 9,Clg4b,MMP-9<...

Mouse HEK293 Cells
MMP-9 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 78.4 kDa and the accession number is P41245-1.
TMPY-01248 MMP-9 Protein, Human, Recombinant

MANDP2,MMP-9,GELB,matrix metallopeptidase ...

Human HEK293 Cells
MMP-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 76.3 kDa and the accession number is P14780.
TMPY-00888 MMP-9 Protein, Human, Recombinant (His)

MANDP2,CLG4B,GELB,matrix metallopeptidase 9,MMP...

Human HEK293 Cells
MMP-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.7 kDa and the accession number is P14780.
TMPK-00368 MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated

Gelatinase B,MMP-9,MANDP2,CLG4B,GELB

Human HEK293 Cells
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina...
TMPK-00503 MMP-9 Protein, Cynomolgus, Recombinant (His)

MMP-9,CLG4B,Gelatinase B,MANDP2,GELB

Cynomolgus HEK293 Cells
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Cynomolgus, Reco...
TMPK-00367 MMP-9 Protein, Human, Recombinant (His & Avi)

MANDP2,CLG4B,Gelatinase B,GELB,MMP-9

Human HEK293 Cells
Matrix metalloproteinase 9 (MMP9) contributes to this process and deficiencies in the MMP9 lead to impaired healing. Inappropriate expression of MMP9 also contributes to impaired re-epithelialization. Previously we demonstrated that FOXO1 was activated in wound healing but to higher levels in diabetic wounds. To address mechanisms of impaired re-epithelialization we examined MMP9 expression in vivo in full thickness dermal scalp wounds created in experimental K14. MMP-9 Protein, Human, Recombina...
TMPJ-00957 MMP-9 Protein, Mouse, Recombinant (His)

Matrix metalloproteinase-9,92 kDa gelatina...

Mouse HEK293 Cells
Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP-9 (gelatinase B) can degrade a broad range of substrates including gelatin, collagen types IV and V, elastin and proteoglycan core protein. It is believed to act synergistically with interstitial collagenase (MMP1) in the degradation of fibrillar collagens as it degrades their denatured gelatin forms. MMP-9 is produced by ker...
TMPK-00946 EFEMP1 Protein, Human, Recombinant (His)

MLVT,S1-5,Fibulin 3,FBNL,fibrillin-like,MGC111353,FBLN3,FBNL...

Human HEK293 Cells
Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9; TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion. EFEMP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His ...
TMPK-01082 EFEMP1 Protein, Mouse, Recombinant (His)

EFEMP1,MTLV,MGC111353,MLVT,S1-5,DHRD,FBNLFLJ35535,fibrillin-...

Mouse HEK293 Cells
Transversalis fascia EFEMP1, TIMP3 and ELN expressions were decreased, but MMP9 expression was increased in IH patients compared with controls. In IH patients, EFEMP1 was not correlated with TIMP3, but positively correlated with ELN and negatively correlated with MMP9; TIMP3 negatively correlated with MMP9, but positively correlated with ELN.In addition, EFEMP1 suppressed L929 cell migration and invasion. EFEMP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-His ...
TMPH-01316 ECM1 Protein, Human, Recombinant (GST & His & Myc)

Extracellular matrix protein 1,ECM1,Secretory component p85

Human E. coli
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity. ECM1 Protein, Human, Recombinant (GST & His & Myc) is expressed in E. coli expression system with N-10xHis-GST and C-Myc tag. The predicted molecular weight is 52.4 kDa and the accession number is Q16610.
TMPK-01034 SEMA4B Protein, Mouse, Recombinant (His)

SEMA4B,SemC,Semaphorin-C,MGC131831,Semaphorin-4B,KIAA1745,SE...

Mouse HEK293 Cells
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC.
TMPH-01297 DDR1 Protein, Human, Recombinant (aa 21-417, His)

EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...

Human HEK293 Cells
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell...
TMPY-02689 MMP-3 Protein, Human, Recombinant

STMY,MMP-3,matrix metallopeptidase 3,CHDS6,STMY1,SL...

Human E. coli
Matrix metallopeptidase 3 (abbreviated as MMP3) is also known as stromelysin 1 and progelatinase. MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. As a secreted zinc-dependent endopeptidase, MMP3 exerts its functions mainly in the extracellular matrix. This prot...

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MMP-9 Protein, Mouse, Recombinant
Cat.No: TMPY-01919
Species: Mouse
Expression System: HEK293 Cells
MMP-9 Protein, Human, Recombinant
Cat.No: TMPY-01248
Species: Human
Expression System: HEK293 Cells
MMP-9 Protein, Human, Recombinant (His)
Cat.No: TMPY-00888
Species: Human
Expression System: HEK293 Cells
MMP-9 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00368
Species: Human
Expression System: HEK293 Cells
MMP-9 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00503
Species: Cynomolgus
Expression System: HEK293 Cells
MMP-9 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00367
Species: Human
Expression System: HEK293 Cells
MMP-9 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00957
Species: Mouse
Expression System: HEK293 Cells
EFEMP1 Protein, Human, Recombinant (His)
Cat.No: TMPK-00946
Species: Human
Expression System: HEK293 Cells
EFEMP1 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01082
Species: Mouse
Expression System: HEK293 Cells
ECM1 Protein, Human, Recombinant (GST & His & Myc)
Cat.No: TMPH-01316
Species: Human
Expression System: E. coli
SEMA4B Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01034
Species: Mouse
Expression System: HEK293 Cells
DDR1 Protein, Human, Recombinant (aa 21-417, His)
Cat.No: TMPH-01297
Species: Human
Expression System: HEK293 Cells
MMP-3 Protein, Human, Recombinant
Cat.No: TMPY-02689
Species: Human
Expression System: E. coli
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