首页工具

登录

搜索结果

Search Results for " mcp "

Targets Recommended: Raf Ras

31

抑制剂 & 化合物

8

天然产物

31

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T24437	MCP110 MCP-110,MCP 110	Raf; Ras	GPCR/G Protein; MAPK
	MCP110 是 Ras 与 Raf-1 相互作用的抑制剂，可用于治疗人类肿瘤的研究。
T8316	1V209 TLR7 agonist T7	TLR	Immunology/Inflammation
	1V209 (TLR7 agonist T7) 是一种 Toll 样受体 7 (TLR7) 激动剂，可与各种多糖缀合，以改善其水溶性，增强功效并保持低毒性，具有抗肿瘤作用。
T13114	CCR2 antagonist 4 Teijin compound 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2 antagonist 4 (Teijin compound 1) 是高效的、特异性的CCR2拮抗剂，对 CCR2b 的IC50为 180 nM，抑制 MCP-1 诱导的趋化作用的 IC50为 24 nM。
T3479	(RS)-MCPG alpha-MCPG,(±)-MCPG	GluR	Neuroscience
	(RS)-MCPG ((±)-MCPG) 是一种竞争性和选择性 I/II 组代谢型谷氨酸受体 (mGluR) 拮抗剂，可阻断 TBS 诱导的幼年和新生大鼠海马神经元的转变。
T20701	MCPA NSC-2351,Krezone,NSC2351,NSC 2351,U 46 M-Fluid,Raphone	Others	Others
	MCPA（Krezone）是一种高效的苯氧基除草剂。使用 MCPA 会对附近的水资源和土壤资源产生影响。
T23270	(RS)-MCPG disodium salt	Others	Others
	group I/group II metabotropic glutamate receptor antagonist
T61364	LmCPB-IN-1
	LmCPB-IN-1 (compound 35) is a highly effective and reversible covalent inhibitor of Leishmania mexicana cysteine protease B (LmCPB). It exhibits a strong binding affinity with a pK i value of 9.7 [1].
T33228	MCPA-potassium
	MCPA-potassium is a bioactive chemical.
T33227	MCPA-butyl Yamaclean M
	MCPA-butyl is a biochemical.
T13452	(S)-MCPG (+)-MCPG	Others	Others
	(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.
T20948	MCPA-thioethyl HOK 7501,HOK7501,HOK-7501
	MCPA-thioethyl is a biochemical.
T83130	AMCPy
	AMCPy 是一款有效的 EPR 脑成像剂，其优秀的亲脂性使其能够穿透 BBB。
T27987	mCPBG m-Chlorophenylbiguanide
	mCPBG is a potent high affinity agonist of 5-HT3 receptor.
T81054	T-1-MCPAB	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	T-1-MCPAB为一种高效VEGFR-2抑制剂（IC50=0.135 µM），其显著抑制MCF7细胞迁移，适用于癌症相关研究。
T11648	INCB 3284	Others	Others
	INCB 3284, a potent and selective human CCR2 antagonist with an oral bioavailability, is utilized in the study of acute liver failure. It effectively inhibits the binding of monocyte chemoattractant protein-1 (MCP-1) to hCCR2, demonstrating an IC50 of 3.7 nM.
T11079	NMI 8739 n-docosahexaenoyl dopamine,Dha-DA conjugate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	NMI 8739 (n-docosahexaenoyl dopamine) 是 D2 自身受体的激动剂。 NMI 8739 减少 NO 的产生并引起 CCL-20、MCP-1 和 IL-6 释放的浓度依赖性抑制。
T4674	SB297006 SB 297006	CCR	Immunology/Inflammation; Microbiology/Virology
	SB297006 是一种CCR3拮抗剂，IC50为39 nM。它能够显著抑制 CCL11 处理的神经祖细胞的增殖和神经球形成。
T16091	MK-0812 Succinate	Others; CCR	Immunology/Inflammation; Microbiology/Virology; Others
	MK-0812 Succinate 是一种选择性CCR2拮抗剂。
T19230	CCR2 antagonist 4 hydrochloride Teijin compound 1 hydrochloride	Others	Others
	CCR2 antagonist 4 hydrochloride is a specific CCR2 antagonist (IC50s: 180 nM for CCR2b). It potently inhibits MCP-1-induced chemotaxis (IC50: 24 nM).
T78806	PPARδ agonist 9	PPAR	DNA Damage/DNA Repair; Metabolism
	PPARδ agonist9 (compound 21) 作为PPARδ激动剂，展现出EC50为3.6 nM的活性。在体内实验中，PPARδ agonist9能有效降低小鼠血清中MCP-1水平，并在LDLr-KO模型中显著抑制动脉粥样硬化的发展，其抑制率达50-60%。
T80059	Complement factor I	Endogenous Metabolite	Metabolism
	Complement factor I，一丝氨酸蛋白酶，可与辅助因子H (FH)、补体受体1 (CR1/CD35)、C4结合蛋白 (C4BP) 或膜辅助因子蛋白 (MCP/CD46) 结合，调控液相及/或细胞表面补体系统的活性。
T68721	Cantharidin imide
	Cantharidin imide is a PP1/2A inhibitor found in Canarthis vesicatoria. It inhibits proliferation of colorectal cancer cells, increases MCP-1, IL-6, and IL-β levels, and inhibits differentiation and resorptive activity of osteoclasts. This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
T36198	Avenanthramide-C methyl ester
	Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells.
T37644	Bengamide B
	Potent inhibitor of NF-κB activation (IC50 = 85 nM); decreases IκBα phosphorylation. Attenuates LPS-induced nitric oxide production and expression of TNF-α, IL-6 and MCP. Suppresses proliferation of HeLa and HCT116 cells. Anti-inflammatory and antitumor. Hu et al (2007) Regulation of c-Src nonreceptor tyrosine kinase activity by bengamide A through inhibition of methionine aminopeptidases. Chem.Biol. 14 764 PMID:17656313 \|Johnson et al (2012) Myxobacteria versus sponge-derived alkaloids: the be...
T82233	HCAR2 agonist 1
	HCAR2 agonist 1 (Compound 9n) 是一种偏向Gi蛋白的变构调节剂，能够激活Gi蛋白相关的信号传导通路。该化合物展现了明显的抗炎效果，能够显著降低促炎细胞因子（TNF-α、IL-1β、IL-6 和 MCP-1）的mRNA表达水平，并在结肠炎小鼠模型中增强正位激动剂的抗炎作用。
T36130	22(S)-hydroxy Cholesterol 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol
	22(S)-hydroxy Cholesterol is a synthetic oxysterol and a modulator of the liver X receptor (LXR). [1] t prevents monocyte chemoattractant protein 1 (MCP-1) expression induced by the LXR agonist GW 3965 in primary hepatocytes and downregulates mRNA expression of the LXR target genes CD36, ACSL1, and SCD-1 in human myotubes. It decreases triacylglycerol and diacylglycerol synthesis from labeled palmitate and acetate, respectively, in human myoblasts by 50% when used at a concentration of 10 uM. 22...
T71884	ß-Carboline-1-carboxylic acid
	β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not Hep...
T11647	INCB 3284 dimesylate	Others	Others
	INCB 3284 dimesylate is a selective and orally bioavailable human CCR2 antagonist, inhibiting monocyte chemoattractant protein-1 binding to hCCR2 (IC50: 3.7 nM). It can be used in the research of acute liver failure.
T7499	TAK-779 Takeda 779	HIV Protease; CXCR; CCR	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	TAK-779 (Takeda 779) 是一种非肽类CCR5和CXCR3 拮抗剂，对CCR5的Ki 值为 1.1 nM，并选择性抑制R5 HIV-1。
T37861	Talabostat
	Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Talabostat is a nonselective DPP-IV inhibitor, inhibiting DPP8/9, FAP, DPP2 and some other DASH family enzymes essentially as potently as it inhibits DPP-IV[1]. Talabostat stimulates the immune system by triggering a proinflammatory form of cell death in monocytes and macrophages known as pyroptosis. The inhibition of two serine proteases, DPP8 and DPP9,...
T14845	BX471 hydrochloride ZK-811752 hydrochloride	Others	Others
	BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.

化合物

Cat.No: T24437

Synonym: MCP-110,MCP 110

Target: Raf, Ras

Cat.No: T8316

Synonym: TLR7 agonist T7

Target: TLR

CCR2 antagonist 4

Cat.No: T13114

Synonym: Teijin compound 1

Target: CCR

Cat.No: T3479

Synonym: alpha-MCPG,(±)-MCPG

Target: GluR

Cat.No: T20701

Synonym: NSC-2351,Krezone,NSC2351,NSC 2351,U 46 M-Fluid,Raphone

Target: Others

(RS)-MCPG disodium salt

Cat.No: T23270

Target: Others

Cat.No: T61364

MCPA-potassium

Cat.No: T33228

Cat.No: T33227

Synonym: Yamaclean M

Cat.No: T13452

Synonym: (+)-MCPG

Target: Others

MCPA-thioethyl

Cat.No: T20948

Synonym: HOK 7501,HOK7501,HOK-7501

Cat.No: T83130

Cat.No: T27987

Synonym: m-Chlorophenylbiguanide

Cat.No: T81054

Target: VEGFR

Cat.No: T11648

Target: Others

Cat.No: T11079

Synonym: n-docosahexaenoyl dopamine,Dha-DA conjugate

Target: Dopamine Receptor

Cat.No: T4674

Synonym: SB 297006

Target: CCR

MK-0812 Succinate

Cat.No: T16091

Target: Others, CCR

CCR2 antagonist 4 hydrochloride

Cat.No: T19230

Synonym: Teijin compound 1 hydrochloride

Target: Others

PPARδ agonist 9

Cat.No: T78806

Target: PPAR

Complement factor I

Cat.No: T80059

Target: Endogenous Metabolite

Cantharidin imide

Cat.No: T68721

Avenanthramide-C methyl ester

Cat.No: T36198

Cat.No: T37644

HCAR2 agonist 1

Cat.No: T82233

22(S)-hydroxy Cholesterol

Cat.No: T36130

Synonym: 22(S)-hydroxy Cholesterol,22β-hydroxy Cholesterol

ß-Carboline-1-carboxylic acid

Cat.No: T71884

INCB 3284 dimesylate

Cat.No: T11647

Target: Others

Cat.No: T7499

Synonym: Takeda 779

Target: HIV Protease, CXCR, CCR

Cat.No: T37861

BX471 hydrochloride

Cat.No: T14845

Synonym: ZK-811752 hydrochloride

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T6413	Bindarit 宾达利,AF2838	CCR	Immunology/Inflammation; Microbiology/Virology
	Bindarit (AF2838) 是单核细胞趋化蛋白MCP-1/CCL2，MCP-3/CCL7和MCP-2/CCL8的选择性抑制剂，具有抗炎作用。
TC0036	Compound Lup-20(29)-en-3-yl acetate	IL Receptor; VEGFR; Others; TNF; COX	Angiogenesis; Apoptosis; Immunology/Inflammation; Neuroscience; Others; Tyrosine Kinase/Adaptors
	Lup-20(29)-en-3-yl acetate 是 Lupeol 的衍生物，通过下调 TNF-α、IL-1β、MCP-1、COX-2、VEGF 和颗粒酶 B 来抑制类风湿性关节炎的进展。
T4S0795	Berberrubine chloride 9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline	IL Receptor	Immunology/Inflammation
	Berberrubine chloride (9-Berberoline Chloride) 是一种黄连素的有效代谢物，能够改善动物模型中溃疡性结肠炎的症状。
T5688	Micheliolide	NOS; NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Micheliolide 是一种倍半萜内酯，能够抑制各种炎症反应。它能减弱高糖刺激的NF-κB 活化，IκBα的降解，和MCP-1，TGF-β1，FN 在鼠系膜细胞的表达。
TN1154	Nepetin 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素	Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮，具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T4S0350	Licochalcone B 甘草查尔酮 B,甘草查尔酮B	Beta Amyloid; Others	Neuroscience; Others
	Licochalcone B 是从Glycyrrhiza inflate 根中提取的。它能够抑制淀粉样蛋白 β 自聚集作用 (IC50=2.16 μM) ，分解预先形成的 Aβ42原纤维，并通过螯合金属离子抑制金属诱导的 Aβ42聚集。
TN5593	Euphohelioscopin A
	Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity
T38285	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))	Others	Others
	C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))是成熟髓鞘中主要的硫酸盐类化合物。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) 在大鼠小脑中发现活跃的髓发生鞘化反应时积累率高于C24 3'-sulfo 半乳糖甘油酰胺。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))与C 型凝集素和免疫球蛋白样受体相互作用使对LMIR5的亲和力高。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))诱导嗜碱细胞产生MCP-1，可通过增加LMIR5激活NFAT，但不能诱导肥大细胞。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))在体外与CD1d 结合，并增加游离小鼠脾细胞的增殖。

天然产物

Cat.No: T6413

Synonym: 宾达利,AF2838

Target: CCR

Compound Lup-20(29)-en-3-yl acetate

Cat.No: TC0036

Target: IL Receptor, VEGFR, Others, TNF, COX

Berberrubine chloride

Cat.No: T4S0795

Synonym: 9-Berberoline Chloride,Beroline,Beroline Chloride,小檗红碱,Berberrubine,9-Berberoline

Target: IL Receptor

Cat.No: T5688

Target: NOS, NF-κB, COX

Cat.No: TN1154

Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Target: Calcium Channel, Histamine Receptor

Cat.No: T4S0350

Synonym: 甘草查尔酮 B,甘草查尔酮B

Target: Beta Amyloid, Others

Euphohelioscopin A

Cat.No: TN5593

C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Cat.No: T38285

Synonym: C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02104	MCP-2 Protein, Mouse, Recombinant (His & NusA) MCP-2,Mcp2,chemokine (C-C motif) ligand 8,...	Mouse	E. coli
	MCP-2 Protein, Mouse, Recombinant (His & NusA) is expressed in E. coli expression system with His and NusA tag. The predicted molecular weight is 66 kDa and the accession number is Q9Z121.
TMPY-00118	MCP-1/CCL2 Protein, Human, Recombinant (His) SCYA2,HC11,MCAF,HSMCR30,MCP-1,MCP1,GDCF-2,...	Human	P. pastoris (Yeast)
	MCP-1/CCL2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.1 kDa and the accession number is P13500.
TMPY-01866	MCP-3 Protein, Human, Recombinant (His) SCYA7,MARC,FIC,SCYA6,NC28,MCP-3,chemokine (C-C moti...	Human	E. coli
	MCP-3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.5 kDa and the accession number is P80098.
TMPY-04680	MCP-2 Protein, Human, Recombinant (His) SCYA10,MCP2,chemokine (C-C motif) ligand 8,HC14,	Human	P. pastoris (Yeast)
	MCP-2 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 10.3 kDa and the accession number is P80075.
TMPY-04671	MCP-5 Protein, Mouse, Recombinant (His) chemokine (C-C motif) ligand 12,MCP-5,Scya12,CCL12	Mouse	P. pastoris (Yeast)
	Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 ...
TMPY-04173	MCP-3 Protein, Mouse, Recombinant (His) chemokine (C-C motif) ligand 7,mcp3,marc,fic,Scya7,...	Mouse	E. coli
	MCP-3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.7 kDa and the accession number is A9Z1Z1.
TMPY-00564	MCP-4 Protein, Human, Recombinant (His) MCP-4,CCL13,SCYL1,NCC-1,MCP4,NCC1,CKb10,SC...	Human	P. pastoris (Yeast)
	Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils, basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable of inducing crucial immuno-modulatory responses through its effects on epithelial, muscular and endothelial cells. Similar to other CC chem...
TMPY-01887	MCP-2 Protein, Human, Recombinant (SUMO) HC14,MCP-2,chemokine (C-C motif) ligand 8,SCYA10,	Human	E. coli
	MCP-2 Protein, Human, Recombinant (SUMO) is expressed in E. coli expression system with SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P80075-1.
TMPY-00606	MCP-1/CCL2 Protein, Mouse, Recombinant (His) AI323594,HC11,Sigje,MCP-1,MCAF,Scya2,JE,SMC-CF,...	Mouse	Baculovirus Insect Cells
	MCP-1/CCL2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPK-00916	MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) MCP-1,MCP1,SCYA2,GDCF-2,MCAF,CCL2,SMC-CF,H...	Cynomolgus	HEK293 Cells
	MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 9.79 kDa and the accession number is P61274.
TMPY-05653	MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated MCP-1,chemokine (C-C motif) ligand 2,HC11,SMC-CF,	Mouse	Baculovirus Insect Cells
	MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P10148.
TMPK-00010	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) MCP-1,MCAF,GDCF-2,SMC-CF,C-C motif chemokine 2,SCYA...	Human	HEK293 Cells
	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500.
TMPK-00011	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated SMC-CF,HC11,MCAF,MCP1,MCP-1,HSMCR30,C-C mo...	Human	HEK293 Cells
	MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11.5 kDa and the accession number is P13500.
TMPY-01027	Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) carnitine palmitoyltransferase 1B (muscle),AV080368,Mcp<...	Mouse	HEK293 Cells
	Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. It is a 226 amino acid (aa) protein that has a conserved pattern of six cysteines and one potential glycosylation site. The granule-derived mouse mast cell proteases-1 and -2 (mMCP-1 and -2) colocalize in similar quantities in mucosal mast cells but micrograms of mMCP-1 compared w...
TMPK-00532	CD46 Protein, Cynomolgus, Recombinant (His) CD46,MCP,TLX,MIC10,AHUS2,TRA2.10	Cynomolgus	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPY-03863	CAPG Protein, Human, Recombinant capping protein (actin filament), gelsolin-like,HEL-S-66,	Human	E. coli
	CAPG, also known as actin Regulatory Protein CAPG, is a a member of the gelsolin/villin family. Members of this family are actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG may also play an important role in macrophage function.
TMPK-00570	CD46 Protein, Canine, Recombinant (His) CD46,AHUS2,TRA2.10,LOC609365,TLX,MCP,MIC10,Membrane...	Canine	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPY-02023	CD46 Protein, Human, Recombinant (His) AHUS2,MIC10,CD46 molecule, complement regulatory protein,TLX...	Human	HEK293 Cells
	CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic...
TMPK-00879	CCR2b Protein-VLP, Human, Recombinant C-C CKR-2,CCR2,MCP-1-R,CCR-2,CMKBR2	Human	HEK293 Cells
	The chemokine (C-C motif) receptor 2B (CCR2B) is one of the two isoforms of the receptor for monocyte chemoattractant protein-1 (CCL2), the major chemoattractant for monocytes, involved in an array of chronic inflammatory diseases. The actin-binding protein filamin A (FLNa) as a protein that associates with the carboxyl-terminal tail of CCR2B. FLNa emerges as an important protein for controlling the internalization and spatial localization of the CCR2B receptor in different dynamic membrane stru...
TMPJ-00852	CCL2 Protein, Rat, Recombinant (His) C-C motif chemokine 2,Small-inducible cytokine A2,Monocyte c...	Rat	HEK293 Cells
	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the cognate receptor CCR2, and together this signaling pair has been shown to have multiple pro-tumorigenic roles, from mediating tumor growth and angiogenesis to recruiting and usurping host stromal cells to support tumor progression. CCL2 is found in the circulation, where it has ...
TMPJ-00010	CCL8 Protein, Human, Recombinant Monocyte Chemoattractant Protein 2,C-C Motif Chemokine 8,	Human	E. coli
	CCL8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12 KDa and the accession number is P80075.
TMPJ-00591	CCL8 Protein, Human, Recombinant (His) SCYA8,MCP-2,Monocyte Chemotactic Protein 2,C-C Moti...	Human	HEK293 Cells
	CCL8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 13 KDa and the accession number is AAI26243.1.
TMPJ-00028	CCL2 Protein, Mouse, Recombinant Ccl2,Je,Mcp1,C-C motif chemokine 2,Platelet-derived...	Mouse	E. coli
	C-C motif chemokine 2 (CCL2) is a member of the C-C or β chemokine family. Mouse CCL2 shares 82% amino acid (aa) identity with rat CCL2 over the entire sequence, and 58%, 56%, 55%, 53% and 53% aa identity with human, equine, porcine, bovine and canine CCL2, respectively. Fibroblasts, glioma cells, smooth muscle cells, endothelial cells, lymphocytes and mononuclear phagocytes can produce CCL2 either constitutively or upon mitogenic stimulation, but monocytes and macrophages appear to be the major...
TMPJ-00009	CCL2 Protein, Human, Recombinant C-C motif chemokine 2,MCAF,CCL2,MCP-1,Monocyte chem...	Human	E. coli
	The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation...
TMPH-03328	Mcpt1 Protein, Rat, Recombinant (Myc)	Rat	E. coli
	Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650.
TMPH-03330	Mcpt4 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	N/A. Mcpt4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P97592.
TMPH-03329	Mcpt2 Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates. Mcpt2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P00770.
TMPH-02779	Mcpt4 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Mcpt4 Protein, Mouse, Recombinant (His) is expressed in Yeast.
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-\|-His-9' bond of angiotensin I and the 'Phe-4-\|-Ala-5' and 'Tyr-10-\|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPJ-00968	NAMPT Protein, Human, Recombinant (His) PBEF,PBEF1,Nicotinamide phosphoribosyltransferase,NAmPRTase,...	Human	E. coli
	Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are ...
TMPY-04411	YES1 Protein, Human, Recombinant (His & GST) HsT441,c-yes,YES proto-oncogene 1, Src family tyrosine kinas...	Human	Baculovirus Insect Cells
	Proto-oncogene tyrosine-protein kinase Yes, also known as Proto-oncogene c-Yes, p61-Yes and YES1, is a cytoplasm protein that belongs to the protein kinase superfamily, Tyr protein kinase family and SRC subfamily. YES1 / c-Yes contains one protein kinase domain, one SH2 domain and one SH3 domain. It is thought that the subcellular distribution of Src-family tyrosine kinases, including c-Yes binding to the cellular membrane, is membranous and/or cytoplasmic. YES1 / c-Yes protein tyrosine kinase i...

重组蛋白

MCP-2 Protein, Mouse, Recombinant (His & NusA)

Cat.No: TMPY-02104

Species: Mouse

Expression System: E. coli

MCP-1/CCL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00118

Species: Human

Expression System: P. pastoris (Yeast)

MCP-3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01866

Species: Human

Expression System: E. coli

MCP-2 Protein, Human, Recombinant (His)

Cat.No: TMPY-04680

Species: Human

Expression System: P. pastoris (Yeast)

MCP-5 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04671

Species: Mouse

Expression System: P. pastoris (Yeast)

MCP-3 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04173

Species: Mouse

Expression System: E. coli

MCP-4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00564

Species: Human

Expression System: P. pastoris (Yeast)

MCP-2 Protein, Human, Recombinant (SUMO)

Cat.No: TMPY-01887

Species: Human

Expression System: E. coli

MCP-1/CCL2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00606

Species: Mouse

Expression System: Baculovirus Insect Cells

MCP-1/CCL2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00916

Species: Cynomolgus

Expression System: HEK293 Cells

MCP-1/CCL2 Protein, Mouse, Recombinant (His), Biotinylated

Cat.No: TMPY-05653

Species: Mouse

Expression System: Baculovirus Insect Cells

MCP-1/CCL2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00010

Species: Human

Expression System: HEK293 Cells

MCP-1/CCL2 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00011

Species: Human

Expression System: HEK293 Cells

Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01027

Species: Mouse

Expression System: HEK293 Cells

CD46 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00532

Species: Cynomolgus

Expression System: HEK293 Cells

CAPG Protein, Human, Recombinant

Cat.No: TMPY-03863

Species: Human

Expression System: E. coli

CD46 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00570

Species: Canine

Expression System: HEK293 Cells

CD46 Protein, Human, Recombinant (His)

Cat.No: TMPY-02023

Species: Human

Expression System: HEK293 Cells

CCR2b Protein-VLP, Human, Recombinant

Cat.No: TMPK-00879

Species: Human

Expression System: HEK293 Cells

CCL2 Protein, Rat, Recombinant (His)

Cat.No: TMPJ-00852

Species: Rat

Expression System: HEK293 Cells

CCL8 Protein, Human, Recombinant

Cat.No: TMPJ-00010

Species: Human

Expression System: E. coli

CCL8 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00591

Species: Human

Expression System: HEK293 Cells

CCL2 Protein, Mouse, Recombinant

Cat.No: TMPJ-00028

Species: Mouse

Expression System: E. coli

CCL2 Protein, Human, Recombinant

Cat.No: TMPJ-00009

Species: Human

Expression System: E. coli

Mcpt1 Protein, Rat, Recombinant (Myc)

Cat.No: TMPH-03328

Species: Rat

Expression System: E. coli

Mcpt4 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03330

Species: Rat

Expression System: E. coli

Mcpt2 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03329

Species: Rat

Expression System: E. coli

Mcpt4 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02779

Species: Mouse

Expression System: P. pastoris (Yeast)

Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02778

Species: Mouse

Expression System: E. coli

NAMPT Protein, Human, Recombinant (His)

Cat.No: TMPJ-00968

Species: Human

Expression System: E. coli

YES1 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04411

Species: Human

Expression System: Baculovirus Insect Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼