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Search Results for " il-17 "

Targets Recommended: Interleukin

36

抑制剂 & 化合物

1

天然产物

1

化合物库

57

重组蛋白

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Cat. No.	Product Name
L6750	活血化瘀中药单体库		580 compounds
	580种来源于常见活血化瘀中药的单体化合物，是药物开发、药理研究等领域的有效工具。

化合物库

活血化瘀中药单体库

Cat.No: L6750

Compounds: 580

Cat. No.	Product Name	Target	Signaling Pathways
T36526	IL-17 modulator 4	Interleukin	Immunology/Inflammation
	IL-17 modulator 4 是 IL-17 modulator 1 的前药，IL-17 modulator 1 是 IL-17 的有效调节剂。
T40127	IL-17 modulator 3
	IL-17 modulator 3 (US20200247785A1) is a chemical compound that acts as an IL-17 modulator. It has potential applications in researching inflammation, cancer, and autoimmune diseases.
T40106	IL-17 modulator 1
	IL-17 modulator 1 is an orally active small molecule. It is highly efficacious in modulating IL-17 and can effectively prevent, treat, or ameliorate various diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis.
T36525	IL-17 modulator 1 disodium
	IL-17 Modulator 1 (disodium) is a potent, orally active compound, known for its high efficacy in modulating IL-17. This compound is extensively utilized for researching various diseases such as psoriasis, ankylosing spondylitis, and psoriatic arthritis[1].
T40107	IL-17 modulator 4 sulfate
	IL-17 modulator 4 sulfate is a prodrug of IL-17 modulator 1 . IL-17 modulator 1 is an orally active, highly efficacious IL-17 modulator.
T72598	IL-17 modulator 5
	IL-17 modulator5 是IL-17的抑制剂，其IC50值为 1 nM。
T63089	(R)-IL-17 modulator 4
	(R)-IL-17 modulator 4 是 IL-17 modulator 4 的 R 构型形式，是 IL-17 modulator 1 的前药。其中 IL-IL-17 modulator 1 是一种高效的、口服具有活力的 IL-17 调节剂。
T1846	Y-320 Y320	IL Receptor; Lipase; Interleukin	Immunology/Inflammation; Metabolism
	Y-320 是一种免疫调节剂，能阻碍IL-15刺激CD4 T 细胞后的IL-17的产生，IC50=20~60 nM。
T76778	Risankizumab Risankizumab rzaa,SKYRIZI,ABBV 066,BI-655066	IL Receptor	Immunology/Inflammation
	Risankizumab (BI 655066) 是一种人源化靶向 IL-23 p19 亚基的 IgG 单克隆抗体(Kd <10 pM)。 Risankizumab 能抑制人 IL-23 在小鼠脾细胞中诱导的 IL-17 产生，IC50 值为 2 pM。Risankizumab 可用于预防和治疗如寻常型银屑病、银屑病关节炎、广泛性脓疱型银屑病和红皮病型银屑病类的免疫性和炎症性疾病。
T76779	Brodalumab LP 0160,KHK-4827,AMG-827	IL Receptor	Immunology/Inflammation
	Brodalumab (AMG 827) 是一种人源靶向白介素 17 受体 (IL-17R) IgG2 的单克隆抗体，常作为免疫抑制剂来治疗银屑病和牛皮藓。
T38105	Ixekizumab LY2439821	IL Receptor; Interleukin	Immunology/Inflammation
	Ixekizumab (LY2439821) 是一种人源化 IgG4 单克隆抗体，可选择性结合和中和白细胞介素 IL-17A ，Kd 值<3 pM。Ixekizumab 科阻断 IL-17A 与 IL-17RA 的结合，但不与其他 IL-17 家族成员结合。Ixekizumab 用于治疗中重度斑块型银屑病、银屑病关节炎和牛皮癣。
T24984	5J-4	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	5J-4 是一种有效的钙释放激活钙通道 (CRAC) 和钙池操纵性钙内流(SOCE) 阻滞剂。 5J-4 减少 IL-17 的产生并降低 RORα 和 RORγt 的表达。
T70084	Dersalazine Dersalazine Free Base	IL Receptor; Platelet aggregation	Immunology/Inflammation; Others
	Dersalazine (Dersalazine Free Base) 是血小板活化因子抑制剂，通过下调 IL-17表达，在不同啮齿动物型结肠炎中发挥肠道抗炎活性，对溃疡性结肠炎患者具有潜在疗效。
T16832	S18-000003	ROR	Metabolism
	S18-000003 是口服有活性的维甲酸相关孤儿受体 (RORγt) 选择性抑制剂，在竞争性结合试验中，对 hRORγt 的 IC50值小于 30 nM。它对 RORγt 的选择性比其他 ROR 家族成员 (IC50>10 μM)更高。它可用于银屑病的研究，胸腺畸变风险较低。
T2601	Vidofludimus SC12267,4sc-101	Dehydrogenase; DNA/RNA Synthesis; Interleukin	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism
	Vidofludimus (SC12267) 是一种新型的二氢乳清酸脱氢酶 (DHODH) 小分子抑制剂，可在不影响淋巴细胞增殖的条件下抑制IL-17的分泌。
T12079	ML604440	Proteasome	Proteases/Proteasome; Ubiquitination
	ML604440 是一种特异性的、有效的、细胞可渗透的蛋白酶体 β1i (LMP2) 亚基抑制剂，能够破坏 MHC I 类细胞表面表达，IL-6 分泌以及 naïve T helper 向 17 T helper 细胞的分化。它可以改善实验性结肠炎和 EAE 疾病。
T30953	CK 17 CK-17,CK17
	CK-17 is an interleukin-1 antagonist and an IL-1 blocker, which inhibits fibroblast proliferation in a concentration-dependent manner.
T77098	Netakimab
	Netakimab为抗IL-17单克隆抗体。Nerelimomab适用于研究强直性脊柱炎、银屑病关节炎及中重度斑块状银屑病。
T25109	ARN-6039 ARN 6039,ARN6039
	ARN-6039 is an orally available inverse agonist of RORγ for Autoimmune Neuroinflammatory Demyelinating Disease. The activity of ARN-6039 against RORγ was demonstrated in a RORγ-activated IL-17A Prom/LUCPorter assay in HEK 293 cells (360 nM) and in IL-17 r
T12752	RORγt Inverse agonist 3	Others	Others
	RORγt Inverse agonist 3 is a potent, selective and orally active inverse agonist of RORγ(EC50s of 0.22 μM and 0.15 μM for hRORγ and RORγt (human IL-17 cells), respectively).
T61709	AMS-17
	AMS-17 is a potent NLRP3 inhibitor, which effectively suppresses microglia activation both in vitro and in vivo. Additionally, AMS-17 exhibits inhibitory effects on various cytokines, such as caspase-1, TNF-α, IL-1β, and inducible nitric oxide synthase (iNOS), in N9 cells. Given these properties, AMS-17 holds promise as a valuable tool for investigating inflammation-associated neurological disorders [1].
T40123	BMS-986251
	BMS-986251 is a potent and specific RORγt inverse agonist that exerts its action via oral administration. It shows an EC 50 of 12 nM for RORγt GAL4. In human whole blood assay, BMS-986251 effectively inhibits IL-17 with an EC 50 of 24 nM. Furthermore, BMS-986251 exhibits strong therapeutic effects in mouse acanthosis and Imiquimod-induced models, which are commonly used preclinical models for psoriasis.
T12750	ROR agonist-1	Others	Others
	ROR agonist-1 is a potent and orally bioavailable the retinoic acid receptor-related orphan receptor C2 (RORC2) inverse agonist(inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5).
T77171	Efineptakin alfa
	Efineptakin alfa (NT-17) 是一种长效重组人 IL-7。 Efineptakin alfa 支持人和小鼠体内 CD4+和 CD8+细胞的增殖和存活。 Efineptakin alfa 可用于胶质母细胞瘤的研究。
T61302	Anti-inflammatory agent 17
	Anti-inflammatory agent 17 an orally active anti-inflammatory agent, demonstrates potent efficacy in inhibiting the release of IL-6 and TNF-α without causing cytotoxicity in in vitro experiments. Furthermore, in vivo studies confirm its anti-inflammatory activity. Given its attributes, Compound 17 holds promise for investigating Acute lung injury (ALI) [1].
T78168	NLRP3-IN-17	NOD-like Receptor (NLR)	Immunology/Inflammation
	NLRP3-IN-17为一种高效、选择性且具有口服活性的NLRP3炎性体抑制剂，IC50为7 nM。该化合物在小鼠模型中显著抑制NLRP3依赖的IL-1β分泌，适用于慢性炎症疾病的研究。
T72254	RORγt inverse agonist 26
	RORγt inverse agonist 26 是一种有效的 RORγt 反向激动剂。RORγt inverse agonist 26 调节 Th17 细胞的分化并抑制 IL-17的产生。RORγt inverse agonist 26 具有研究炎症和自身免疫性疾病的潜力。
T63874	RORγt inverse agonist 28
	RORγt inverse agonist 28 是有效的 RORγt 反向激动剂。RORγt inverse agonist 28 能够调节 Th17 细胞的分化，并抑制 IL-17 的产生。RORγt inverse agonist 28 对炎症和自身免疫性疾病表现出研究潜力。
T36042	17(R)-HDHA
	Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals. 17(R)-HDHA is the primary oxygenation product of DHA when exposed to aspirin-inhibited cyclooxygenase-2. 17(R)-HDHA serves as a precursor to resolvins and has intrinsic biological activity, such as the inhibition of TNFα-induced IL-1β expression in human glioma cells.
T83700	IRBP (651-670) (human) TFA IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)
	IRBP651-670（Interphotoreceptor retinoid-binding protein (651-670)）是IRBP（亦称为retinoid-binding protein 3）的肽段，参与色素再生，通过将视黄醇和视黄醛从光感受细胞传输到视网膜色素上皮。在C57BL/6小鼠中，利用IRBP651-670诱导自身免疫性葡萄膜炎，这些小鼠携带H-2b单体型。用IRBP651-670（300 µg/动物）免疫增加了小鼠眼部IL-1β、IL-6、IL-17、TNF-α和IFN-γ水平，免疫细胞浸润及光感受器损伤。
T71933	GNE-3500
	GNE-3500 is a Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C (RORc or RORγ) Inverse Agonist. Retinoic acid receptor-related orphan receptor C (RORc, RORγ, or NR1F3) is a nuclear receptor that plays a major role in the production of interleukin (IL)-17. Considerable efforts have been directed toward the discovery of selective RORc inverse agonists as potential treatments of inflammatory diseases such as psoriasis and rheumatoid arthritis. GNE-3500 poss...
T63559	IRAK4-IN-22
	IRAK4-IN-22 是选择性的、口服具有活力的、强效的 IRAK4 抑制剂，能够作用于 IRAK4 (IC50: 3 nM) 和 TAK1 (IC50: 17 nM)。IRAK4-IN-21 对 IL-23 的产生表现出有效的抑制作用，其 IC50值为0.10 μM。IRAK4-IN-21 能够用于研究自身免疫性疾病，如斑块状银屑病和银屑病关节炎。
T64300	Vimirogant hydrochloride
	Vimirogant (VTP-43742) hydrochloride 是一种口服具有活力的、选择性的 RORγt 抑制剂 (IC50: 17 nM, Ki: 3.5 nM)，选择性比 RORα 和 RORβ 大于 1000 倍。Vimirogant hydrochloride 能够抑制小鼠脾细胞的 Th17 分化和 IL-17A 分泌，其 IC50 值为 57 nM，且不影响 Th1，Th2 或 Treg 细胞的分化。Vimirogant hydrochloride 能够用于自身免疫性疾病的研究。
T68182	3-Hydroxykynurenamine
	3-Hydroxykynurenamine, also known as 3-Hydroxy-L-kynurenamine or 3-HKA, is a biogenic amine produced via an alternative pathway of tryptophan metabolism. In vitro, 3-HKA has an anti-inflammatory profile by inhibiting the IFN-γ mediated STAT1/NF-κΒ pathway in both mouse and human dendritic cells (DCs) with a consequent decrease in the release of pro-inflammatory chemokines and cytokines, most notably TNF, IL-6, and IL12p70. 3-HKA has protective effects in an experimental mouse model of psoriasis ...
T76840	Vunakizumab
	Vunakizumab (Anti-Human IL17A Recombinant Antibody) 是一种重组的人源化 IgGκ 单克隆抗体，可以靶向 IL-17A 并抑制其与 IL-17受体的相互作用。Vunakizumab 可用于研究银屑病关节炎、强直性脊柱炎、多发性硬化症和炎症性关节炎等自身免疫性疾病。
T35927	C2 L-threo Ceramide (d18:1/2:0) C2 L-threo Ceramide (d18:1/2:0)
	C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides. It stimulates cholesterol efflux in CHO cells expressing the human ABCA1 receptor when used at a concentration of 10 μM, however, this efflux is 50% less than that stimulated by C2 ceramide . C2 L-threo Ceramide inhibits IL-4 production by 17% in EL4 T cells stimulated with phorbol 12-myristate 13-acetate when used at a concentration of 10 μM. It also induces cell cycle arrest in the G0/G1...

化合物

IL-17 modulator 4

Cat.No: T36526

Target: Interleukin

IL-17 modulator 3

Cat.No: T40127

IL-17 modulator 1

Cat.No: T40106

IL-17 modulator 1 disodium

Cat.No: T36525

IL-17 modulator 4 sulfate

Cat.No: T40107

IL-17 modulator 5

Cat.No: T72598

(R)-IL-17 modulator 4

Cat.No: T63089

Cat.No: T1846

Synonym: Y320

Target: IL Receptor, Lipase, Interleukin

Cat.No: T76778

Synonym: Risankizumab rzaa,SKYRIZI,ABBV 066,BI-655066

Target: IL Receptor

Cat.No: T76779

Synonym: LP 0160,KHK-4827,AMG-827

Target: IL Receptor

Cat.No: T38105

Synonym: LY2439821

Target: IL Receptor, Interleukin

Cat.No: T24984

Target: Calcium Channel

Cat.No: T70084

Synonym: Dersalazine Free Base

Target: IL Receptor, Platelet aggregation

Cat.No: T16832

Target: ROR

Cat.No: T2601

Synonym: SC12267,4sc-101

Target: Dehydrogenase, DNA/RNA Synthesis, Interleukin

Cat.No: T12079

Target: Proteasome

Cat.No: T30953

Synonym: CK-17,CK17

Cat.No: T77098

Cat.No: T25109

Synonym: ARN 6039,ARN6039

RORγt Inverse agonist 3

Cat.No: T12752

Target: Others

Cat.No: T61709

Cat.No: T40123

Cat.No: T12750

Target: Others

Efineptakin alfa

Cat.No: T77171

Anti-inflammatory agent 17

Cat.No: T61302

Cat.No: T78168

Target: NOD-like Receptor (NLR)

RORγt inverse agonist 26

Cat.No: T72254

RORγt inverse agonist 28

Cat.No: T63874

Cat.No: T36042

IRBP (651-670) (human) TFA

Cat.No: T83700

Synonym: IRBP651-670,Interphotoreceptor Retinoid-Binding Protein (651-670)

Cat.No: T71933

Cat.No: T63559

Vimirogant hydrochloride

Cat.No: T64300

3-Hydroxykynurenamine

Cat.No: T68182

Cat.No: T76840

C2 L-threo Ceramide (d18:1/2:0)

Cat.No: T35927

Synonym: C2 L-threo Ceramide (d18:1/2:0)

Cat. No.	Product Name	Target	Signaling Pathways
TN2539	1beta-Hydroxyalantolactone	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	1beta-Hydroxyalantolactone 是从药用植物大英花的花头中分离出的小分子化合物，可抑制细胞中TNF-α、IL-17、IFN-γ的表达，促进TNF-α、IFN-γ、IL-17的分泌，可防治类风湿性关节炎。

天然产物

1beta-Hydroxyalantolactone

Cat.No: TN2539

Target: IL Receptor, TNF

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01172	IL-17 Protein, Mouse, Recombinant (His) CTLA8,IL-17,IL-17A,Inter...	Mouse	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato...
TMPY-00470	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) interleukin 17A,IL-17,IL...	Human	HEK293 Cells
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.
TMPY-00053	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant CTLA8,IL17,IL-17,IL<...	Human	E. coli
	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.7 kDa and the accession number is Q16552&NP_443104.1.
TMPY-02900	IL-17A Protein, Mouse, Recombinant IL-17A,Ctla8,Ctla-8,interleukin 17	Mouse	E. coli
	IL-17A Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.5 kDa and the accession number is Q62386.
TMPY-02886	IL-17A Protein, Human, Recombinant IL-17,白细胞介素,interleukin 17A,CTLA8...	Human	E. coli
	IL-17A Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPY-01371	IL-17RA Protein, Human, Recombinant (His) CANDF5,CD217,CDw217,IL-17	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1.
TMPJ-01208	IL-17RE Protein, Mouse, Recombinant (His) interleukin 17 receptor E,IL-17 r...	Mouse	HEK293 Cells
	IL-17RE Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-42 KDa and the accession number is Q8BH06.
TMPJ-01230	IL-17RE Protein, Human, Recombinant (hFc) IL-17RE,interleukin 17 receptor E...	Human	HEK293 Cells
	IL-17RE Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q8NFR9.
TMPJ-00376	IL-17RD Protein, Human, Recombinant (hFc) IL17Rhom,IL17RD,IL	Human	HEK293 Cells
	Interleukin-17 receptor D (IL-17 RD), also known as SEF (similar expression to FGFs), is a type I transmembrane protein that is found in both the cytoplasm and plasma membrane. IL-17RD functions as a feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. It may inhibit FGF-induced FGFR1 tyrosine phosphorylation, regulate the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK By similarity, and mediate JNK activation ...
TMPK-00703	IL-17Rc Protein, Human, Recombinant (hFc) IL-17 receptor C,IL-17RC...	Human	HEK293 Cells
	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
TMPY-04332	IL-17A Protein, Human, Recombinant (T26A, His) CTLA-8,CTLA8,IL-17A,interleukin 17	Human	Baculovirus Insect Cells
	IL-17A Protein, Human, Recombinant (T26A, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q16552.
TMPY-05183	IL-17A Protein, Human, Recombinant, Biotinylated interleukin 17A,IL-17,白细胞介素,白介素,<...	Human	E. coli
	IL-17A Protein, Human, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 15.7 kDa and the accession number is Q16552.
TMPJ-01215	IL-17RD Protein, Mouse, Recombinant (hFc) Interleukin-17 receptor-like protein,IL-	Mouse	HEK293 Cells
	IL-17RD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-120 KDa and the accession number is Q8JZL1.
TMPK-00575	IL-23R Protein, Canine, Recombinant (His) IBD17,IL-23 R,IL-23 receptor	Canine	HEK293 Cells
	IL-23R Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.31 kDa and the accession number is A0A8I3PXL0.
TMPJ-01216	IL-17RD Protein, Mouse, Recombinant (His) Sef,mSef,Interleukin-17 receptor-like protein,I...	Mouse	HEK293 Cells
	IL-17RD Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-65 KDa and the accession number is Q8JZL1.
TMPK-00353	IL-23R Protein, Human, Recombinant (aa 24-355, His) IL-23 R,IBD17,IL-23 receptor	Human	HEK293 Cells
	IL-23R Protein, Human, Recombinant (aa 24-355, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.15 kDa and the accession number is Q5VWK5-1.
TMPY-03471	IL-17RB Protein, Mouse, Recombinant (His) interleukin 17 receptor B,IL-17Rh...	Mouse	HEK293 Cells
	IL-17RB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is Q9JIP3-1.
TMPY-03568	IL-17A Protein, Human, Recombinant (His) CTLA-8,CTLA8,白介素,interleukin 17A,IL17<...	Human	P. pastoris (Yeast)
	IL-17A Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q16552.
TMPY-04162	IL-17RB Protein, Mouse, Recombinant (hFc) IL-17Rh1,IL17RH1,interle...	Mouse	HEK293 Cells
	IL-17RB Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q543U7.
TMPK-00652	IL-23R Protein, Cynomolgus, Recombinant (His) IL-23 R,IL-23 receptor,IBD17	Cynomolgus	HEK293 Cells
	IL-23R Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.03 kDa and the accession number is G7NWY5.
TMPY-00844	IL-17RD Protein, Human, Recombinant (His) IL-17RD,interleukin 17 receptor D...	Human	HEK293 Cells
	IL-17RD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.5 kDa and the accession number is Q8NFM7-1.
TMPJ-01444	IL-17A Protein, Cynomolgus, Recombinant (His) CTLA-8,CTLA8,IL17A,IL-17...	Cynomolgus	HEK293 Cells
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synt...
TMPK-01094	IL-23R Protein, Mouse, Recombinant (His) IL-23 receptor,Il23r,IBD17,IL...	Mouse	HEK293 Cells
	IL-23R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 41.48 kDa and the accession number is Q8K4B4.
TMPK-01036	IL-17A Protein, Mouse, Recombinant (His & Avi) interleukin 17A,IL17A,CTLA-8,...	Mouse	HEK293 Cells
	IL-17A Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPK-01266	IL-17A Protein, Cynomolgus, Recombinant (His & Avi) IL17,interleukin 17A,IL<...	Cynomolgus	HEK293 Cells
	IL-17A Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is A0A2K5TTB0.
TMPK-00975	IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated IL-17CTLA-8,interleukin 17A,CTLA-...	Human	HEK293 Cells
	IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is Q16552-1.
TMPK-01037	IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated IL17A,interleukin 17A,IL...	Mouse	HEK293 Cells
	IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 18 kDa and the accession number is Q62386-1.
TMPY-05119	IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated interleukin 17 receptor A,hIL-17R...	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 61.6 kDa and the accession number is Q96F46-1.
TMPY-06391	IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated CANDF5,CDw217,interleukin 17 receptor A,h<...	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 36.71 kDa and the accession number is Q96F46-1.
TMPY-05120	IL-17RA Protein, Human, Recombinant (His), Biotinylated IL-17RA,CD217,hIL-17...	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.9 kDa and the accession number is Q96F46-1.
TMPY-06390	IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated interleukin 17 receptor A,IL17R,C...	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 61.99 kDa and the accession number is Q96F46-1.
TMPY-05430	IL-17RA Protein, Human, Recombinant (hFc) hIL-17R,interleukin 17 receptor A...	Human	HEK293 Cells
	IL-17RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.2 kDa and the accession number is Q96F46-1.
TMPY-03906	IL-17 Protein, Canine, Recombinant 白细胞介素,interleukin 17A,白介素	Canine	E. coli
	IL-17 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.2 kDa and the accession number is C6L8D7.
TMPY-04710	IL-17 Protein, Rhesus, Recombinant 白介素,白细胞介素,interleukin 17A	Rhesus	Baculovirus Insect Cells
	IL-17 Protein, Rhesus, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 15.1 kDa and the accession number is A0A8J8YJF1.
TMPY-04888	IL-17 Protein, Rabbit, Recombinant 白细胞介素,白介素,interleukin 17A	Rabbit	E. coli
	IL-17 Protein, Rabbit, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is G1SLF2.
TMPY-03931	IL-17 Protein, Marmoset, Recombinant interleukin 17A,白介素,白细胞介素	Marmoset	E. coli
	IL-17 Protein, Marmoset, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.4 kDa and the accession number is A5HJM0.
TMPY-04609	IL-17 Protein, Rabbit, Recombinant (His) 白细胞介素,白介素,interleukin 17A	Rabbit	Baculovirus Insect Cells
	IL-17 Protein, Rabbit, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is G1SLF2.
TMPJ-00251	IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) IL-3 receptor subunit alpha,IL-3R subunit ...	Mouse	HEK293 Cells
	IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His) is expressed in HEK293 mammalian cells with C-8xHis tag. The predicted molecular weight is 50-65 KDa and the accession number is P26952.
TMPY-01049	IL-1 beta/IL-1F2 Protein, Human, Recombinant IL-1 beta,interleukin 1, beta,IL-1B,interl...	Human	E. coli
	IL-1 beta/IL-1F2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is P01584.
TMPK-00405	IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated IL-7R-alpha,IL-7R,ILRA,IL	Human	HEK293 Cells
	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
TMPJ-01237	IL-17D Protein, Human, Recombinant IL17D,Interleukin-17D,IL...	Human	E. coli
	The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. IL-17 family proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence ho...
TMPK-00060	IL-17B Protein, Mouse, Recombinant (His) IL20,interleukin 17B,interleukin 20,IL...	Mouse	E. coli
	IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/IL-17RB expression patterns and biological activities in cancer and highlight issues that remain to be addressed to better characterize IL-17B and its receptor as potential targets for enhancing the effectiveness of the existing cancer therapies.
TMPY-04275	IL-36RN/IL-1F5 Protein, Mouse, Recombinant Fil1δ,AI413231,RP23-176J12.6,Fil1...	Mouse	E. coli
	IL-36RN/IL-1F5 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is Q9QYY1.
TMPJ-00046	IL-17F Protein, Human, Recombinant IL17F,白介素,IL-17F,Interle...	Human	E. coli
	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage mat...
TMPY-02872	IL-36 gamma Protein, Human, Recombinant (aa 18-169) IL-1H1,IL1RP2,白介素,IL-1F9,IL	Human	E. coli
	IL-36 gamma Protein, Human, Recombinant (aa 18-169) is expressed in E. coli expression system. The predicted molecular weight is 17 kDa and the accession number is Q9NZH8-1.
TMPJ-00060	IL-25/IL17E Protein, Human, Recombinant (His) 白细胞介素,IL17E,白介素,IL-17E,<...	Human	HEK293 Cells
	Interleukin 25 (IL-25) belongs to the Interleukin 17 (IL-17) family of proteins, which is comprised of six members (IL-17, IL-17B through IL-17F). These proteins are secreted and are structurally related by sharing a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus. With the exception of IL-17B, which exists as a non-covalently linked dimer, all IL-17 family members are disulfide-linked dimers. IL-17 family proteins are pro-inflammator...
TMPK-01169	IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated Interleukin-23 subunit α,Interleukin-23 subunit alpha,IL...	Mouse	HEK293 Cells
	The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma.
TMPK-00055	IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated 白介素,IL-17E,IL-25,IL1...	Human	HEK293 Cells
	IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling responses in epithelial cells and type 2 lymphocytes, which initiates, propagates, and sustains type 2 immunity. The function of IL-25 in allergic diseases such as asthma has been well established, and now also is extended to diseases such as inflammatory bowel disease and cancer.
TMPH-00779	IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)	Guinea pig	E. coli
	Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible fo...
TMPK-00084	IL-17C Protein, Human, Recombinant (His & Avi) IL-17C,Cytokine CX2,IL17...	Human	HEK293 Cells
	Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by sig...
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重组蛋白

IL-17 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01172

Species: Mouse

Expression System: HEK293 Cells

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)

Cat.No: TMPY-00470

Species: Human

Expression System: HEK293 Cells

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-00053

Species: Human

Expression System: E. coli

IL-17A Protein, Mouse, Recombinant

Cat.No: TMPY-02900

Species: Mouse

Expression System: E. coli

IL-17A Protein, Human, Recombinant

Cat.No: TMPY-02886

Species: Human

Expression System: E. coli

IL-17RA Protein, Human, Recombinant (His)

Cat.No: TMPY-01371

Species: Human

Expression System: HEK293 Cells

IL-17RE Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01208

Species: Mouse

Expression System: HEK293 Cells

IL-17RE Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-01230

Species: Human

Expression System: HEK293 Cells

IL-17RD Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00376

Species: Human

Expression System: HEK293 Cells

IL-17Rc Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00703

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (T26A, His)

Cat.No: TMPY-04332

Species: Human

Expression System: Baculovirus Insect Cells

IL-17A Protein, Human, Recombinant, Biotinylated

Cat.No: TMPY-05183

Species: Human

Expression System: E. coli

IL-17RD Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01215

Species: Mouse

Expression System: HEK293 Cells

IL-23R Protein, Canine, Recombinant (His)

Cat.No: TMPK-00575

Species: Canine

Expression System: HEK293 Cells

IL-17RD Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01216

Species: Mouse

Expression System: HEK293 Cells

IL-23R Protein, Human, Recombinant (aa 24-355, His)

Cat.No: TMPK-00353

Species: Human

Expression System: HEK293 Cells

IL-17RB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03471

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (His)

Cat.No: TMPY-03568

Species: Human

Expression System: P. pastoris (Yeast)

IL-17RB Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-04162

Species: Mouse

Expression System: HEK293 Cells

IL-23R Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00652

Species: Cynomolgus

Expression System: HEK293 Cells

IL-17RD Protein, Human, Recombinant (His)

Cat.No: TMPY-00844

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPJ-01444

Species: Cynomolgus

Expression System: HEK293 Cells

IL-23R Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01094

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-01036

Species: Mouse

Expression System: HEK293 Cells

IL-17A Protein, Cynomolgus, Recombinant (His & Avi)

Cat.No: TMPK-01266

Species: Cynomolgus

Expression System: HEK293 Cells

IL-17A Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00975

Species: Human

Expression System: HEK293 Cells

IL-17A Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01037

Species: Mouse

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated

Cat.No: TMPY-05119

Species: Human

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated

Cat.No: TMPY-06391

Species: Human

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05120

Species: Human

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated

Cat.No: TMPY-06390

Species: Human

Expression System: HEK293 Cells

IL-17RA Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05430

Species: Human

Expression System: HEK293 Cells

IL-17 Protein, Canine, Recombinant

Cat.No: TMPY-03906

Species: Canine

Expression System: E. coli

IL-17 Protein, Rhesus, Recombinant

Cat.No: TMPY-04710

Species: Rhesus

Expression System: Baculovirus Insect Cells

IL-17 Protein, Rabbit, Recombinant

Cat.No: TMPY-04888

Species: Rabbit

Expression System: E. coli

IL-17 Protein, Marmoset, Recombinant

Cat.No: TMPY-03931

Species: Marmoset

Expression System: E. coli

IL-17 Protein, Rabbit, Recombinant (His)

Cat.No: TMPY-04609

Species: Rabbit

Expression System: Baculovirus Insect Cells

IL-3R alpha/CD123 Protein, Mouse, Recombinant (aa 17-331, His)

Cat.No: TMPJ-00251

Species: Mouse

Expression System: HEK293 Cells

IL-1 beta/IL-1F2 Protein, Human, Recombinant

Cat.No: TMPY-01049

Species: Human

Expression System: E. coli

IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated

Cat.No: TMPK-00405

Species: Human

Expression System: HEK293 Cells

IL-17D Protein, Human, Recombinant

Cat.No: TMPJ-01237

Species: Human

Expression System: E. coli

IL-17B Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00060

Species: Mouse

Expression System: E. coli

IL-36RN/IL-1F5 Protein, Mouse, Recombinant

Cat.No: TMPY-04275

Species: Mouse

Expression System: E. coli

IL-17F Protein, Human, Recombinant

Cat.No: TMPJ-00046

Species: Human

Expression System: E. coli

IL-36 gamma Protein, Human, Recombinant (aa 18-169)

Cat.No: TMPY-02872

Species: Human

Expression System: E. coli

IL-25/IL17E Protein, Human, Recombinant (His)

Cat.No: TMPJ-00060

Species: Human

Expression System: HEK293 Cells

IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01169

Species: Mouse

Expression System: HEK293 Cells

IL-25/IL-17E Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00055

Species: Human

Expression System: HEK293 Cells

IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)

Cat.No: TMPH-00779

Species: Guinea pig

Expression System: E. coli

IL-17C Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00084

Species: Human

Expression System: HEK293 Cells

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