669
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T30479 |
Bis-T-23
Bis T-23,Bis-T 23,AG1717 |
HIV Protease | Microbiology/Virology; Proteases/Proteasome |
Bis-T-23是一种肌动蛋白依赖性达纳敏低聚物的促进剂,是一种 HIV-I 整合酶抑制剂,是泰尔普斯丁衍生物。Bis-T-23可以促进肌动蛋白依赖性的dynamin 寡聚化。Bis-T-23可用于HIV 和慢性肾脏疾病(CKD)的研究。 | |||
T18614 |
Bis-Tos-PEG4
Tetraethylene glycol di(p-toluenesulfonate),PROTAC Linker 16,1,11-Bis(tosyloxy)-3,6,9-trioxaundecane |
Others; PROTAC Linker | Others; PROTAC |
Bis-Tos-PEG4 (PROTAC Linker 16) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T22276 |
Bis(maltolato)oxovanadium(IV)
双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) |
Phosphatase; Others | Metabolism; Others |
Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂,也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA,PTP1B,HPTPβ和SHP2的IC50分别为 126 nM,109 nM,26 nM 和 201 nM。 | |||
T22606 |
BIS-TRIS
|
Others | Others |
Bis-Tris 是常用的缓冲液之一。 | |||
T17823 |
Diethylene glycol bis(p-toluenesulfonate)
二乙二醇双对甲苯磺酸酯,Bis-Tos-PEG2,Diethylene glycol di(p-toluenesulfonate) |
Others; PROTAC Linker | Others; PROTAC |
Diethylene glycol bis(p-toluenesulfonate) (Bis-Tos-PEG2) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17636 |
Bis-Tos-PEG7
|
Others; PROTAC Linker | Others; PROTAC |
Bis-Tos-PEG7 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16302 |
NH-bis(PEG3-azide)
|
Others | Others |
NH-bis(PEG3-azide) 是一种属于 PEG 类的 PROTAC 连接体,可用于合成 PROTAC 分子。 | |||
T14635 |
Bis-PEG3-NHS ester
|
Others | Others |
Bis-PEG3-NHS ester 是用于抗体-药物偶联的不可切割的 3 单元 PEG 接头。 | |||
T9269 |
N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline
N1-[3,5-双(三氟甲基)苯基]-2-氯乙酰胺,N-(3,5-Bis(trifluoromethyl)phenyl)-2-chloroacetamide |
Others | Others |
N-Chloroacetyl-3,5-bis(trifluoromethyl)aniline (KM1954) 是一种杀虫剂,对第一阶段Ae 有效。 LC50 值为 125μM 的埃及伊蚊幼虫。 | |||
T3572 |
NSC 15364
1,3-Bis(4-aminophenyl)urea,NSC15364 |
Apoptosis; Others; VDAC | Apoptosis; Membrane transporter/Ion channel; Others |
NSC 15364 (1,3-Bis(4-aminophenyl)urea) 是一种 VDAC1寡聚化和细胞凋亡抑制剂。 | |||
T0565 |
Bis(2-chloroethyl)amine hydrochloride
|
Others | Others |
Bis(2-chloroethyl)amine hydrochloride 用作医药中间体。 | |||
T0534 |
Bis(4-cyanophenyl)methanol
双(4-氰基苯基)甲醇,4, 4'-Dicyanobenzhydrol |
Others | Others |
Bis(4-cyanophenyl)methanol (4, 4'-Dicyanobenzhydrol) 是 Letrozole 的代谢物。 | |||
T18479 |
NH-bis(C1-Boc)
亚氨基二乙酸二异丁酯 |
Others | Others |
Boc-NH-C6-Br 是一种不可切割的接头,用于抗体-药物偶联物。 | |||
T17319 |
1,2-Bis(2-iodoethoxy)ethane
|
Others; PROTAC Linker | Others; PROTAC |
1,2-Bis(2-iodoethoxy)ethane 是一种属于 PEG 类的 PROTAC linker,可用于 MT802 和 SJF620 的合成。其中 MT-802 和 SJF620 都是 PROTAC BTK 降解剂,DC50分别为 1 和 7.9 nM。 | |||
T1345 |
1,1-Bis(Methylthio)-2-Nitroethylene
|
Others | Others |
1,1-Bis(Methylthio)-2-Nitroethylene (1,1-BMNE) 具有多种生化和生理作用。它可以抑制参与药物和其他化合物代谢的酶的活性,如细胞色素P450和乙酰胆碱酯酶。 | |||
T21505 |
Suberoyl bis-hydroxamic acid
SBHA,软木肟酸,Suberohydroxamic acid |
Apoptosis; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair |
Suberoyl bis-hydroxamic acid (SBHA) 是一种竞争性且可透过细胞的HDAC1和HDAC3抑制剂,ID50值分别为 0.25 μM 和 0.30 μM。它使肿瘤细胞易于凋亡并促进线粒体凋亡途径,可研究甲状腺髓样癌。 | |||
T7077 |
2,3-BIS(N-BUTYLTHIO)-1,4-NAPHTHALENEDION
|
Others | Others |
2,3-BIS(N-BUTYLTHIO)-1,4-NAPHTHALENEDION 是中间体。 | |||
T8952 |
bis(p-methoxyphenyl)iodonium bromide
Di(p-anisyl)iodonium Bromide,双(4-甲氧基苯基)碘鎓 溴化物 |
Others | Others |
bis(p-methoxyphenyl)iodonium bromide (Di(p-anisyl)iodonium Bromide) 是一种溴化物盐,由两个对甲氧基苯基碘鎓分子通过溴离子连接在一起组成。它已被用作合成聚合物、制备纳米颗粒和合成有机染料的试剂。它还被用于研究有机分子的结构和反应性,以及研究无机分子的结构与反应性。 | |||
T38745 |
Bis-methacrylate-PEG5
Bis-methacrylate-PEG5 |
||
Bis-methacrylate-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40944 |
Bis-acrylate-PEG6
Bis-acrylate-PEG6 |
||
Bis-acrylate-PEG6 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40494 |
Bis-isopropyl-PEG1
Bis-isopropyl-PEG1 |
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Bis-isopropyl-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T38749 |
Bis-propargyl-PEG10
Bis-propargyl-PEG10 |
||
Bis-propargyl-PEG10 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T19445 |
N-Bis(2-hydroxypropyl)nitrosamine
Di(2-hydroxypropyl)nitrosamine,DHPN,Diisopropanolnitrosamine,N-亚硝基二异丙醇胺 |
Others | Others |
N-Bis(2-hydroxypropyl)nitrosamine (DHPN) 是具有致癌活性的一种试剂。 | |||
T8672 |
2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE
BisOPP-A,双酚0PPA |
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
2,2-BIS(2-HYDROXY-5-BIPHENYLYL)PROPANE 是针对促甲状腺激素受体(人)。 | |||
T39225 |
Bis-sulfone-PEG3-Azide
Bis-sulfone-PEG3-Azide |
||
Bis-sulfone-PEG3-Azide, a cleavable ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs). | |||
T39297 |
Bis-sulfone-PEG4-DBCO
Bis-sulfone-PEG4-DBCO |
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Bis-sulfone-PEG4-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
TNU0685 |
Dipropofol
4,4-Bis(2,6-di-isopropylphenol) |
GABA Receptor | Membrane transporter/Ion channel; Neuroscience |
Dipropofol (4,4-Bis(2,6-di-isopropylphenol)) is a small molecule GABAA receptor agonist that can be used to study epilepsy. | |||
T83654 |
Dilinoleyl Ketone
Bis(linoleyl) ketone |
Others | Others |
Dilinoleyl Ketone (Bis(linoleyl) ketone) 是一种脂质膜,是一种潜在的核酸载体。 | |||
T39774 |
Bis-CH2-PEG2-acid
Bis-CH2-PEG2-acid |
||
Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T9129 |
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI)
|
p53 | Apoptosis |
Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) 是 p53 的抑制剂,IC50 值为 0.35 μM。 | |||
T9935 |
UCM-1336
3,3′-(Octylimino)bis[N-phenylpropanamide] |
Others | Others |
UCM-1336 (3,3′-(Octylimino)bis[N-phenylpropanamide]) 是一种有效的 ICMT 抑制剂,IC50 为 2 μM,对参与 Ras 翻译后修饰的其他酶具有选择性。 | |||
T65636 |
BIS-TRIS propane
BTP |
Others | Others |
BIS-TRIS propane (BTP) 是镍基和钴基自旋团簇的新型多齿配体,是一种金属螯合剂。Bis-tris propane 常作为两性离子缓冲液使用,可用于PCR、蛋白质结晶研究和MgATPase 酶活力研究。 | |||
T36956 |
Bis-ANS dipotassium
4,4'-Dianilino-1,1'-binaphthyl-5,5'-disulfonic Acid,bis-ANS (potassium salt) |
||
bis-ANS is a high-affinity non-covalent extrinsic fluorescent dye used to analyze protein conformation.[1] Its predominant interaction with proteins is through its hydrophobic phenyl and naphthyl rings.[2] bis-ANS has an excitation maxima of 390 nm.[3] It has an emission maximum of 523 nm when free in solution but undergoes a blue shift with an increase in fluorescence intensity when bound to protein; for example, when bound to intestinal fatty acid binding protein (FAPB2) it has emission maxima... | |||
T23797 |
Bis(diazoacetyl)butane
1,4-Bis-diazoacetylbutane,Supermutagen,1,4-Bis(diazoacetyl)butane,DAB (mutagen) |
||
Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and carcinogenic activity. | |||
T39075 |
Bis-PEG3-t-butyl ester
Bis-PEG3-t-butyl ester |
||
Bis-PEG3-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T39532 |
Bis-PEG4-t-butyl ester
Bis-PEG4-t-butyl ester |
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Bis-PEG4-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T67967 |
EOB-DTPA
N-((2s)-2-(bis(carboxymethyl)amino)-3-(4-ethoxyphenyl)propyl)-n-(2-(bis(carboxymethyl)amino)ethyl)glycine |
Others | Others |
EOB-DTPA 是一种生化试剂,可由其他化合物合成,常用于核磁共振成像。 | |||
T41129 |
Bis-SS-C3-NHS ester
Bis-SS-C3-NHS ester |
||
Bis-SS-C3-NHS ester is a cleavable linker compound employed in ADC synthesis. It finds application in the construction of antibody-drug conjugates (ADCs). | |||
T17320 |
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane
1-3-bis-carboxyethoxy-2-2-bis-carboxyethoxy-propane |
Others | Others |
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a polyethylene glycol (PEG)-based linker compound suitable for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T10549 |
Bisindolylmaleimide VIII acetate
Ro 31-7549 acetate,Bis VIII acetate |
Apoptosis; PKC | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling |
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) 是一种选择性蛋白激酶 C 抑制剂。它促进 Fas 介导的细胞凋亡,并抑制 T 细胞介导的自身免疫性疾病。 | |||
T40540 |
Bis-PEG6-t-butyl ester
Bis-PEG6-t-butyl ester |
||
Bis-PEG6-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T22678 |
3,5-Bis(4-nitrophenoxy)benzoic acid
3,5-二(4-硝基苯氧基)苯甲酸,Compound W |
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
3,5-Bis(4-nitrophenoxy)benzoic acid (Compound W) 是 γ-secretase 抑制剂。它导致 Aβ42 和 notch-1 Aβ-like peptide 25 (Nβ25) 的释放水平降低。它是母体血清中 3,3’-diiodothyronine sulfate (T2S) 的交叉反应物质,可作为胎儿甲状腺功能减退的标志物。 | |||
T1017 |
Fluorothyl
Fluoroethyl,Flurothyl,Bis(2,2,2-trifluoroethyl) ether,氟替尔 |
Others | Others |
Fluorothyl (Bis(2,2,2-trifluoroethyl) ether) 是一种具有挥发性的液体。 | |||
T18861 |
Triethylene glycol bis(p-toluenesulfonate)
Bis-Tos-PEG3 |
Others | Others |
Triethylene glycol bis(p-toluenesulfonate) is a polyethylene glycol (PEG) derived linker compound, utilized for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1]. | |||
T41130 |
Bis-SS-C3-sulfo-NHS ester
Bis-SS-C3-sulfo-NHS ester |
||
Bis-SS-C3-sulfo-NHS ester is a cleavable ADC linker employed for the synthesis of antibody-drug conjugates (ADCs). | |||
T18537 |
Pentaethylene glycol di(p-toluenesulfonate)
Penta(ethylene glycol) bis(p-toluenesulfonate),二对甲苯磺酸戊乙二醇,Bis-Tos-PEG5 |
Others; PROTAC Linker | Others; PROTAC |
Pentaethylene glycol di(p-toluenesulfonate) (Penta(ethylene glycol) bis(p-toluenesulfonate)) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T20933 |
Bis(p-chlorophenyl)acetic acid
Bis(p-chlorphenyl)essigsaeure,Bis(4-chlorophenyl)acetic acid,DDA (degradation product),DDA |
||
Bis(p-chlorophenyl)acetic acid is a standard for pesticide residue analysis. | |||
T14341 |
ATN-224
四硫钼酸二胆碱,Bis(choline)tetrathiomolybdate |
Others | Others |
ATN-224 (Bis(choline)tetrathiomolybdate) 抑制内皮细胞中的 SOD1 活性,这种作用呈剂量依赖性,IC50 为 17.5±3.7 nM。 ATN-224 是一种口服 Cu2+/Zn2+-超氧化物歧化酶 1 (SOD1) 抑制剂。 | |||
T4604 |
HC-056456
HC 056456,3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide |
Others | Others |
HC-056456 (3,4-Bis(2-thienoyl)-1,2,5-oxadiazole-N-oxide) 是一种有效但不完全选择性的 CatSper 通道阻断剂。它能够减慢 [Na+]i 上升(IC50:3 µM)。 | |||
T30464 |
Bis(2-butoxyethyl) sebacate
ecanedioic acid, bis(2-butoxyethyl) ester,Dibutyoxyethyl sebacate,Decanedioic acid, 1,10-bis(2-butoxyethyl) ester |
||
Bis(2-butoxyethyl) sebacate is a biochemical. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8051 |
Bis(2-methyl-3-furyl)disulfide
双(2-甲基-3-呋喃基)二硫,Bis(2-methyl-3-furyl)disulphide |
Others | Others |
Bis(2-methyl-3-furyl)disulfide 是调味剂,能够增强与牛奶相关的产品的自然感,清新感。 | |||
TN7150 |
Pygmaniline B
1,3-Bis-(2,4-dimethoxy-phenyl)-urea,1,3-bis(2,4-dimethoxyphenyl)urea,N,N'-bis(2,4-dimethoxyphenyl)urea |
Others | Others |
Pygmaniline B (1,3-bis(2,4-dimethoxyphenyl)urea) 是一种海洋来源的天然产物,存在于Lichina pygmaea。 | |||
TWO2724 |
N,N-Bis(2-hydroxyethyl)-p-phenylenediami
|
Others | Others |
N,N-Bis(2-hydroxyethyl)-p-phenylenediami 是中间体。 | |||
T3S1541 |
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan
rel-(8R,8'R)-dimethyl-(7S,7'R)-bis(3,4-m,(7S,7'R)-双(3,4-亚甲二氧苯基)-rel-(8R,8'R)-二甲基四氢呋喃 |
Others | Others |
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan 为肉豆蔻果实中发现的化学成分。 | |||
TN1444 |
Bis(dihydrochelerythrinyl)amine
bis[6-(5,6-dihydrochelerythrinyl)]amine |
Antifection | Microbiology/Virology |
BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). | |||
TN7143 |
1,3-Diphenethylurea
N,N'-Diphenethylurea,1,3-bis(2-phenylethyl)urea,N,N'-Bis(phenethyl)urea,1,3-双(2-苯乙基)脲,ZINC150349,N,N'-bis(2-phenylethyl)urea |
Others | Others |
1,3-Diphenethylurea (N,N'-Bis(phenethyl)urea) 是一种海洋来源的天然产物,存在于 Lissoclinum patella。 | |||
T6S1688 |
(1E,6E)-Bis(demethoxy)curcumin
(1E,6E)-1,7-双(4-羟基苯基)庚-1,6-二烯-3,5-二酮,Curcumin III,双去甲氧基姜黄素,Didemethoxycurcumin,BDMC |
Apoptosis; Others; Autophagy | Apoptosis; Autophagy; Others |
(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) 是姜黄素的天然去甲氧基衍生物,具有抗炎和抗癌活性。 | |||
T4797 |
DEHP
Bis(2-ethylhexyl) phthalate,邻苯二甲酸二(2-乙基己)酯 |
Others; Endogenous Metabolite | Metabolism; Others |
DEHP (Bis(2-ethylhexyl) phthalate) 是内源性代谢产物的一种。 | |||
T38799 |
2,3-Bis(3-indolylmethyl)indole
|
||
2,3-Bis(3-indolylmethyl)indole exhibits concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption. | |||
TN3513 |
Bis-5,5-nortrachelogenin
|
Others | Others |
Bis-5,5-nortrachelogenin has anti-allergic activity, it inhibited NO production with IC50 value of 48.6 microM. | |||
T20473 |
Bis(2-ethylhexyl) terephthalate
|
||
Bis(2-ethylhexyl) terephthalate is an agent of biochemical. | |||
T0978 |
Pantethine
LBF disulfide,Pantosin,Pantetina,Bis-pantethine,泛硫乙胺(维生素B5),泛硫乙胺,Pantomin,D-Pantethine |
Endogenous Metabolite | Metabolism |
D-Pantethine (Pantomin) 是泛酸的二聚体形式, 是生产辅酶 A 的中间体。D-Pantethine 能够作为膳食补充剂,用于改善血液胆固醇和研究痤疮。 | |||
T21159 |
Bis(2-ethylhexyl) sebacate
Di(2-ethylhexyl) Sebacate,Dioctyl Sebacate |
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Bis(2-ethylhexyl) sebacate is used as a plasticizer in preparing ion-selective electrodes. It is an important raw material and intermediate used in organic synthesis, agrochemicals, pharmaceuticals and dyestuff fields. | |||
T20071 |
Bis(2-ethylhexyl)hexanedioate
NSC-56775,NSC56775,NSC 56775 |
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Bis(2-ethylhexyl)hexanedioate is a diester. It is used as a plasticizer in the preparation of various polymers. | |||
T20574 |
Magnesium lactate
Bis(lactato)magnesium |
||
Magnesium lactate is a magnesium donor and buffering agent. | |||
TN4621 |
N1,N10-Bis(p-coumaroyl)spermidine
|
Glucosidase | Metabolism |
N1,N10-Bis(p-coumaroyl)spermidine 对α-葡萄糖苷酶有抑制作用,可从苜蓿的草本植物中提取。 | |||
TN6187 |
3,5,8,3'-Tetramethoxy-6,7,4',5'-bis(methylenedioxy)flavone
|
||
3,5,8,3'-Tetramethoxy-6,7,4',5'-bis(methylenedioxy)flavone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6187,CAS号为 82668-93-7。 | |||
TN5650 |
Rubranol
1,7-Bis(3,4-dihydroxyphenyl)-3-heptanol |
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Rubranol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5650,CAS号为 211126-61-3。 | |||
TN2897 |
3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane
|
Others | Others |
3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2897,CAS号为 408324-01-6。 | |||
TN5762 |
1,7-Bis(3,4-dihydroxyphenyl)heptane-3,5-diyl diacetate
|
||
1,7-Bis(3,4-dihydroxyphenyl)heptane-3,5-diyl diacetate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5762,CAS号为 138870-97-0。 | |||
TN2513 |
1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol
|
Others | Others |
1,7-Bis(4-hydroxyphenyl)hept-6-en-3-ol is a natural product from Alpinia galanga. | |||
TN2515 |
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
|
Antifection | Microbiology/Virology |
(4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in the range of 1-3 microg/mL. | |||
TN2512 |
1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one
|
Others | Others |
1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one是一种天然产物,属于姜科山姜属,其产品编号为 TN2512,CAS号为 1083200-79-6。1,7-Bis(4-hydroxyphenyl)hept-1-en-3-one可用作对照参考。 | |||
TN6235 |
1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
|
||
1,7-Bis(4-hydroxyphenyl)hepta-1,4,6-trien-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6235,CAS号为 149732-52-5。 | |||
TN2514 |
1,7-Bis(4-hydroxyphenyl)hept-6-en-3-one
|
Others | Others |
1,7-Bis(4-hydroxyphenyl)hept-6-en-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2514,CAS号为 1251830-57-5。 | |||
T82861 |
Bis-(-)-8-demethylmaritidine
|
||
Bis-(-)-8-demethylmaritidine,一种天然生物碱,作为乙酰胆碱酯酶(AChE)抑制剂具有有效性。该化合物适用于阿尔茨海默病的研究。 | |||
TN5443 |
Kaempferol 3,4',7-triacetate
Kaempferol 3,4,7-triacetate,3,7-Bis(acetyloxy)-2-[4-(acetyloxy)phenyl]-5-hydroxy-4H-1-benzopyran-4-one,3,7,4'-Tri-O-acetylkaempferol,[4-(3,7-diacetyloxy-5-hydroxy-4-oxochromen-2-yl)phenyl] acetate |
Others | Others |
Kaempferol 3,4',7-triacetate (3,7,4'-Tri-O-acetylkaempferol) 是椴木草本植物的天然产物。 | |||
TN5749 | 1,7-Bis(4-hydroxyphenyl)-5-hydroxyhept-1-en-3-one | ||
1,7-Bis(4-hydroxyphenyl)-5-hydroxyhept-1-en-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5749,CAS号为 1426059-89-3。 | |||
T75442 |
Galloyl-bis-HHDP glucose
|
||
Galloyl-bis-HHDP glucose (HeT) 是一种鞣花单宁,对绿色假单胞菌具有植物保护作用。 | |||
T6S1529 |
Cynarin
Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1R,3R,4S,5R)-,Cynarine,1,5-Dicaffeoylquinic acid,洋蓟素,金银花 |
Antioxidant; Antiviral; Influenza Virus; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction |
Cynarin (1,5-Dicaffeoylquinic acid) 是一种抗窒息剂,具有抗氧化、抗组胺和抗病毒等多种生物活性。 | |||
TN5661 |
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
|
||
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one shows strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation of human whole blood. | |||
TN3115 |
5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate
|
Others | Others |
5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3115,CAS号为 1269839-24-8。 | |||
TN3339 |
Acetamide, N-[1,1-bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]-
|
Others | Others |
Acetamide, N-[1,1-bis[(acetyloxy)methyl]-3-(4-octylphenyl)propyl]- 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3339,CAS号为 162358-09-0。 | |||
T5736 |
1,3-Dicaffeoylquinic acid
CYNARIN,1,3-二咖啡酰奎宁酸,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid |
Reactive Oxygen Species; Akt; PI3K | Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling |
1,3-Dicaffeoylquinic acid (CYNARIN) 是一种咖啡酰奎宁酸衍生物,具有抗氧化、自由基清除作用。 | |||
TN7201 |
Lauric Acid Diethanolamide
Lauric diethanolamide,N,N-二乙醇十二酰胺,Lauryl diethanolamide,N,N-Bis(2-hydroxyethyl)dodecanamide |
Others | Others |
Lauric Acid Diethanolamide (Lauric diethanolamide) 是一种海洋来源的天然产物,存在于Bacillus sp.。 | |||
T81992 |
Kaempferol 3,7-bis(α-L-rhamnose-D-glucose)
|
||
Kaempferol 3,7-bis(α-L-rhamnose-D-glucose) (化合物1)为Euonymus fortune中存在的黄酮苷。 | |||
TL0007 |
Bisdemethoxycurcumin
双去甲氧基姜黄素,Curcumin III,Didemethoxycurcumin |
Epigenetic Reader Domain; Wnt/beta-catenin | Chromatin/Epigenetic; Cytoskeletal Signaling; Stem Cells |
Bisdemethoxycurcumin (Curcumin III) 是一种具有抗炎及抗氧化作用的姜黄素。 | |||
T5623 |
Bisphenol A
|
Others; Endogenous Metabolite | Metabolism; Others |
Bisphenol A 是酚类内源性代谢合成物,广泛用于环氧树脂和聚碳酸酯塑料的生产。它是生殖、发育和全身毒性物质,常被归类为内分泌干扰物。它与许多疾病有关,包括呼吸系统疾病、心血管疾病、糖尿病、肾脏疾病、肥胖和生殖障碍。 | |||
T19343L |
Glycerol 3-phosphate biscyclohexylammonium salt
|
Endogenous Metabolite | Metabolism |
Glycerol 3-phosphate biscyclohexylammonium salt 是胞质甘油 3-磷酸脱氢酶途径中产生的,即利用 NADH 还原二羟丙酮磷酸的过程。 | |||
TN1445 |
Bisabolangelone
|
p38 MAPK; MAPK | MAPK |
Bisabolangelone 是从没药中分离出来的一种倍半萜衍生物,具有抗炎作用。它通过阻断巨噬细胞内的NF-kappaB 和MAPK 通路抑制脂多糖刺激的炎症,具有抗溃疡作用。 | |||
T37984 |
D-Fructose-1,6-bisphosphate sodium salt hydrate
|
Others | Others |
D-Fructose-1,6-bisphosphate sodium salt hydrate 是碳水化合物代谢的中间体,包括糖酵解和糖异生。在糖酵解过程中,它是由磷酸果糖激酶磷酸化果糖-6-磷酸产生的。由果糖-1,6-二磷酸酶-1介导的逆反应是糖异生的限速步骤之一。同样的反应也发生在植物的叶绿体中,D-Fructose-1,6-bisphosphate sodium salt hydrate 作为还原性戊糖磷酸循环的一部分。由于癌细胞采用糖酵解作为代谢能量产生的主要来源,这一途径已成为癌症化疗的主要靶点。 | |||
T8199 |
(±)-α-Bisabolol
Bisabolol |
Apoptosis; Antioxidant | Apoptosis; oxidation-reduction |
(±)-α-Bisabolol (Bisabolol) 是一种从洋甘菊、念珠菌树等植物精油中提取的倍半萜烯醇,是一种天然防腐剂,具有舒缓、抗刺激、抗炎、抗氧化和抗癌活性。(±)-α-Bisabolol 通过诱导细胞周期停滞、线粒体死亡和抑制 PI3K/Akt 信号通路来发挥作用,对 A549 NSC-LC 细胞产生抗癌作用 (IC50 = 15 μM)。(±)-α-Bisabolol 能强效诱导胶质瘤细胞凋亡。 | |||
T20749 |
Bisabolene
Bisabolene (natural),红没药烯,FEMA 3331,Limene |
Others | Others |
Bisabolene (FEMA 3331) 是从牛至和其他芳香植物中提取的倍半萜。它是一种潜在的抗癌剂,研究表明它可以诱导 A549 癌细胞系凋亡。 | |||
TN5642 |
Leptabiside C
|
||
Leptabiside C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5642,CAS号为 1900703-81-2。 | |||
TN6591 |
Cannabisin B
|
||
Cannabisin B possesses considerable antiproliferative activity and that it may be utilised as a promising chemopreventive agent against hepatoblastoma disease. It induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arre | |||
TN2498 |
1,4-Epidioxybisabola-2,10-dien-9-one
|
Others | Others |
1,4-Epidioxybisabola-2,10-dien-9-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2498,CAS号为 170380-69-5。 | |||
TN3520 |
Bisdethiobis(methylthio)gliotoxin
|
PAFR | GPCR/G Protein |
Bisdethiobis(methylthio)gliotoxin is a platelet activating factor (PAF) antagonist. | |||
TMA0379 |
Cannabisin D
|
Others | Others |
Cannabisin D is a natural product from Cannabis sativa L. | |||
TN3518 |
Bisandrographolide A
|
Others | Others |
Bisandrographolide A activates TRPV4 channels, could play a role in some of the effects of Andrographis extract described in traditional medicine. | |||
T73812 |
Phosphatidylinositol 4,5-bisphosphate
|
||
Phosphatidylinositol 4,5-bisphosphate(L-alpha-Phosphatidylinositol-4,5-bisphosphate)为细胞膜磷脂成分,主要作为磷脂酶C(PLC)与磷酸肌醇3-激酶(PI3K)的底物,充当重要信使。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-02534 |
BAG3 Protein, Mouse, Recombinant (His)
Bcl-2-associated athanogene 3,Bag3,Bcl-2-binding protein |
Mouse | P. pastoris (Yeast) |
BAG3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is Q9JLV1. | |||
TMPH-02535 |
BAG3 Protein, Mouse, Recombinant (His & SUMO)
Bcl-2-associated athanogene 3,Bis,BAG-3,BAG family ... |
Mouse | E. coli |
BAG3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9JLV1. | |||
TMPH-01079 |
CLN5 Protein, Human, Recombinant (His)
CLN5,BMPS,Bis(monoacylglycero)phosphate synthase CL... |
Human | E. coli |
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane. CLN5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 43.5 kDa and ... | |||
TMPH-00773 |
RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO)
|
Glycine max | E. coli |
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. | |||
TMPH-00035 |
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)
|
Agaricus bisporus | Baculovirus Insect Cells |
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments. Involved in the initial step of melanin synthesis. Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell... | |||
TMPH-00036 |
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His & Myc)
|
Agaricus bisporus | E. coli |
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 51.0 kDa and the accession number is O42713. | |||
TMPH-00688 |
YbiS Protein, E. coli O6:H1, Recombinant (His & Myc)
|
E. coli | E. coli |
Responsible, at least in part, for anchoring of the major outer membrane lipoprotein (Lpp) to the peptidoglycan via a meso-diaminopimelyl-L-Lys- bond on the terminal residue of Lpp. YbiS Protein, E. coli O6:H1, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.3 kDa and the accession number is P0AAX9. | |||
TMPH-00736 |
LpxK Protein, E. coli, Recombinant (His & Myc)
|
E. coli | E. coli |
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | |||
TMPH-03084 |
CrtX Protein, Pantoea ananas, Recombinant (E. coli, His & Myc)
Zeaxanthin glucosyltransferase,crtX,ugt101 |
Pantoea ananas | E. coli |
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.7 kDa and the accession number is P21686. | |||
TMPH-03083 |
CrtX Protein, Pantoea ananas, Recombinant (His & Myc)
Zeaxanthin glucosyltransferase,ugt101,crtX |
Pantoea ananas | Baculovirus Insect Cells |
Catalyzes the glycosylation reaction which converts zeaxanthin to zeaxanthin bis(beta-D-glucoside). The reaction proceeds in two steps with the monoglucoside as an intermediate. CrtX Protein, Pantoea ananas, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 51.1 kDa and the accession number is P21686. | |||
TMPH-02549 |
FHIT Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monop... | |||
TMPJ-00858 |
Ezrin Protein, Human, Recombinant
Villin-2,VIL2,EZR,p81,Ezrin,Cytovillin |
Human | E. coli |
Ezrin is expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. The N-terminus of ezrin contains a FERM domain which is further subdivided into three subdomains. The C-terminus contain a ERM domain. As a member of the ERM protein family, Ezrin serves as an intermediate between the plasma membrane and the actin cytoskeleton. It plays a key role in cell surface structure adhesion, migration, and organization. Ezrin probably involved in connections of major cytoskele... | |||
TMPY-03414 |
ABHD10 Protein, Human, Recombinant (aa 53-306, His)
ABHD10,abhydrolase domain containing 10 |
Human | Baculovirus Insect Cells |
Mycophenolic acid (MPA), the active metabolite of the immunosuppressant mycophenolate mofetil (MMF), is primarily metabolized by glucuronidation to a phenolic glucuronide (MPAG) and an acyl glucuronide (AcMPAG). It is known that AcMPAG, which may be an immunotoxic metabolite, is deglucuronidated in human liver. AcMPAG deglucuronidation activity was detected in both human liver cytosol (HLC) and microsomes (HLM). By purification from HLC with column chromatographic purification steps, the en... |