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39

抑制剂 & 化合物

5

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T1070	Cefmetazole sodium 头孢美唑钠,Sodium cefmetazole	Antibacterial; Antibiotic	Microbiology/Virology
	Cefmetazole sodium (Sodium cefmetazole) 是具有广谱抗菌活性的半合成头孢霉素抗生素。它通过与青霉素结合蛋白结合，阻止肽聚糖的交联，导致细胞壁完整性的丧失。它可研究妇科、腹腔内、尿道、呼吸道和皮肤和软组织感染。
T8133	SulfadiMethoxine sodium	Anti-infection; Antibacterial; Antibiotic	Microbiology/Virology
	SulfadiMethoxine sodium 是一种磺胺类抗生素，可研究由多种感染引起的疾病。
T1078	Sulfadimethoxine Sulphadimethoxine,磺胺二甲氧嗪	Antibacterial; Antibiotic	Microbiology/Virology
	Sulfadimethoxine (Sulphadimethoxine) 是一种磺胺类抗生素，用于多种感染引起的疾病的研究。
T0116	Balofloxacin	DNA gyrase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Balofloxacin 是一种具有口服活性的氟喹诺酮类抗生素，可通过干扰 DNA 促旋酶来抑制细菌 DNA 的合成，对革兰氏阴性，革兰氏阳性和厌氧菌具有广谱抗菌活性。它可研究呼吸道，肠道和泌尿道感染。
T6349	Sitafloxacin Hydrate 西他沙星水合物,DU-6859a,DU6859a hydrate	Antibacterial; Antibiotic	Microbiology/Virology
	Sitafloxacin Hydrate (DU-6859a) 是一种口服有效的氟喹诺酮类抗生素，在体外可对抗广泛的革兰氏阳性和阴性细菌有活性。Sitafloxacin 可研究呼吸道感染和尿路感染。
T38236	2′-Deoxy-2′-fluoroguanosine	Nucleoside Antimetabolite/Analog; Influenza Virus	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	2′-Deoxy-2′-fluoroguanosine 是一种核苷类似物，有效抑制流感病毒，抑制A 型和B 型流感病毒的EC90值 <0.35 μM。2′-Deoxy-2′-fluoroguanosine 显著抑制流感病毒在上呼吸道中的复制，从而改善鼻腔炎症和发烧。
T14369	AZD-0284	ROR	Metabolism
	AZD-0284 是核受体 (RORγ) 的选择性反向激动剂。它对呼吸道疾病及斑块型寻常型银屑病具有潜在的应用价值。
T1495	Cefaclor monohydrate Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor	Antibacterial; Antibiotic	Microbiology/Virology
	Cefaclor monohydrate (Cefaclorum) 是一种抗生素，可特异性地结合青霉素结合蛋白。
T0768	Oxolamine citrate 柠檬酸奥索拉明,AF-438 citrate,SKF-9976 citrate	Others	Others
	Oxolamine citrate (AF-438 citrate) 是一种止咳剂，也表现出抗炎作用，可用于呼吸道疾病的研究。
T6436	Cefaclor Panoral,Kefral,Cefaclorum,头孢克洛	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Cefaclor (Panoral) 是一种可特异性结合青霉素结合蛋白的抗生素。
T0284	Sulfogaiacol guaiacolsulfonate,愈创木酚磺酸钾	Others; Antibacterial	Microbiology/Virology; Others
	Sulfogaiacol (guaiacolsulfonate) 是一种镇咳剂，可研究急性呼吸道感染。
T19794	Temafloxacin 替马沙星,Omniflox	Antibiotic	Microbiology/Virology
	Temafloxacin (Omniflox) 是一种喹诺酮类广谱抗菌剂，对革兰氏阳性菌、革兰氏阴性菌和厌氧菌均有效。
T0383	Fenspiride hydrochloride Fenspiride HCl,Pneumorel,Fluiden,Decaspiride,盐酸芬司必利	Adrenergic Receptor; PDE; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Fenspiride hydrochloride (Decaspiride) 是一种口服活性的非甾体抗炎剂，是 H1-组胺受体的拮抗剂，可用于呼吸系统疾病的研究。
T10872L	CP 96021	5-HT Receptor	GPCR/G Protein; Neuroscience
	CP 96021是一组5-HT1受体和5-HT2受体拮抗剂，具有抗炎特性，是治疗胃肠道和呼吸道哮喘的非自身抗溃疡化合物。
T8134	Cefathiamidine	Antibacterial; Antibiotic	Microbiology/Virology
	Cefathiamidine 是一种头孢菌素抗菌剂，可研究由易感细菌引起的感染，还可用于呼吸道、肝脏、五官感觉、尿路感染以及心内膜炎和败血症的研究。
T6234	Ambroxol hydrochloride Mucosolvan,Mucoangin,盐酸氨溴索,Ambroxol HCl	Sodium Channel; Autophagy	Autophagy; Membrane transporter/Ion channel
	Ambroxol hydrochloride (Mucosolvan) 是前药溴己辛的活性代谢产物，是一种葡糖脑苷脂酶伴侣，可增加葡糖脑苷脂酶的活性。它可刺激粘液纤毛作用并清除呼吸道中的空气通道，具有强效祛痰作用。它可诱导肺细胞自噬，有用于帕金森氏病和神经性戈谢病的研究潜力。
T0920	Ambroxol 氨溴索,氨溴索碱,Ambroxolum,NA-872	P450; Autophagy	Autophagy; Metabolism
	Ambroxol (NA-872) 是前药溴己辛的活性代谢产物，是一种分泌溶解剂，具有强效祛痰作用，用于治疗与粘液或过多粘液相关的呼吸道疾病。它可诱导肺组织细胞自噬，有用于帕金森氏病和神经性戈谢病的研究潜力。它是一种葡糖脑苷脂酶伴侣，可增加葡糖脑苷脂酶的活性。
T26974	Cefetamet Hydrochloride Cefetamet HCl,Cefetamet
	Cefetamet is a potent antibiotic to treat respiratory and urinary tract infections.
T32770	Linsidomine CV 664
	Lincydomine is a smooth muscle relaxant, beneficial to the treatment of unstable angina pectoris, but also can open the respiratory tract of humans and guinea pigs.
T68999	Cefonicid (free base)
	Cefonicid (free base) is a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
T33282	Memotine HCl UK-237101,UK-2371,UK 237101,UK 2371,UK2371
	Memotine HCl has antiviral activity against respiratory tract infection and is used as a therapeutic agent for acute respiratory diseases. It is also a memo fracture in the form of hydrochloride, an isoquinoline, with anti-myxovirus and paramyxovirus acti
T68817	Cefonicid monosodium
	Cefonicid monosodium is the salt form of Cefonicid (free base), a second-generation cephalosporin administered intravenously or intramuscularly. Its bactericidal action results from inhibition of cell wall synthesis. It is used for urinary tract infections, lower respiratory tract infections, and soft tissue and bone infections.
T72093	Thiamphenicol glycinate hydrochloride 甲砜霉素甘氨酸酯盐酸盐
	Thiamphenicol glycinate hydrochloride 是一种广谱抗菌剂，可用于呼吸道感染的研究。
T31396	Dexbrompheniramine maleate D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral
	Dexbrompheniramine is an antihistamine with anticholinergic properties. It is used to treat allergic diseases such as hay fever or urticaria. It can compete with histamine for H1 receptor sites on effector cells of the gastrointestinal tract, blood vessel
T75274	Cefetamet
	Cefetamet 是一种头孢类抗生素。Cefetamet 具有研究上、下社区获得性呼吸道感染的潜力。
T9901A-016	TNM001
	TNM001 是一种 RSV 全人源单克隆抗体，可用于由于RSV感染引起的下呼吸道疾病研究。
T38342	11-deoxy Prostaglandin E2 11-deoxy Prostaglandin E2
	11-deoxy Prostaglandin E2 (11-deoxy PGE2) is a stable, synthetic analog of PGE2 . In contrast to PGE2 which has bronchodilation effects, 11-deoxy PGE2 is a powerful bronchoconstrictor and contracts human respiratory tract smooth muscle with potencies ranging from 5 to 30 times higher than PGF2α .
T40971	Dehydroandrographolide succinate potassium sodium salt
	Dehydroandrographolide succinate (potassium sodium salt), derived from the herbal medicine Andrographis paniculata (Burm f) Nees, is a versatile compound highly utilized for the treatment of viral pneumonia and viral upper respiratory tract infections due to its potent immunostimulatory, anti-infective, and anti-inflammatory properties.
T64312	Motugivatrep
	Motugivatrep 是一种强效的 1 型瞬时受体电位 (TRPV1) 拮抗剂。Motugivatrep 在治疗药物、尿台和呼吸系统疾病方面发挥着广泛的作用。
T72105	BMS-433771 dihydrochloride hydrate
	BMS-433771 dihydrochloride hydrate 是一种有效的呼吸道合胞病毒 (RSV) 抑制剂，具有口服活性。BMS-433771 dihydrochloride hydrate 对 A 组和 B 组RSV 均有效，EC50均值为 20 nM。BMS-433771 dihydrochloride hydrate 可用于呼吸道疾病的研究。
T75286	Sitafloxacin hydrochloride
	Sitafloxacin (DU6859a) hydrochloride 是一款有效的口服活性氟喹诺酮类抗生素，它对广泛的革兰氏阳性细菌、革兰氏阴性细菌（包括厌氧菌）及非典型病原体都显示出抗菌活性。该化合物主要用于研究呼吸道感染和尿路感染。
T63214	Lomefloxacin (aspartate)
	Lomefloxacin (SC47111A) aspartate 是广谱的喹诺酮类抗菌剂，能够用于呼吸道感染、胃肠道感染、泌尿生殖系统感染、耳鼻喉感染等疾病的研究。
T21677	Temafloxacin (hydrochloride)
	Temafloxacin (hydrochloride) 是一种抗生素和抗分枝杆菌剂。它用于治疗下呼吸道感染、生殖器和泌尿道感染（如前列腺炎）和皮肤感染。
T60493	Guaiacol Carbonate
	Guaiacol Carbonate 是一种祛痰剂，其作用是通过胃的反射作用，通过胃神经到达延髓中枢，然后再通过外周进入呼吸道，从而起到祛痰作用。
T38458	Faropenem
	Faropenem, a highly efficacious and orally bioavailable beta-lactam antibiotic, exhibits an extensive range of in vitro antimicrobial activity against diverse gram-positive and -negative aerobes and anaerobes. Notably, Faropenem possesses inherent resistance to hydrolysis by virtually all beta-lactamases, including extended-spectrum beta-lactamases and AmpC beta-lactamases. Moreover, Faropenem has been developed as an oral prodrug, namely faropenem medoxomil, for the investigation of respiratory...
T11819	Lascufloxacin 拉库沙星,KRP-AM1977X	Others	Others
	Lascufloxacin () 是一种有效的、具有口服活性的氟喹诺酮类抗菌剂。Lascufloxacin 有效抑制由多种病原体 (包括对喹诺酮类耐药的菌株) 引起的感染。Lascufloxacin 可用于多种传染病的研究，包括下呼吸道感染。
T75287	Sitafloxacin monohydrate
	Sitafloxacin monohydrate (DU6859a) 是一种具有广谱的抗菌活性，并对多种革兰氏阳性和革兰氏阴性细菌（包括厌氧菌）以及非典型病原体有效的口服活性氟喹诺酮类抗生素。它主要用于研究呼吸道感染和尿路感染。
T60417	Fenspiride
	Fenspiride 是 H1-组胺受体的拮抗剂。 Fenspiride 是一种具有口服活性的非甾体类抗炎药，可用于治疗呼吸道感染和中耳炎。 Fenspiride 抑制磷酸二酯酶 4 和磷酸二酯酶 3 的活性，-logIC50 值分别为 4.16+/-0.09 和 3.44+/-0.12。磷酸二酯酶 5 活性也受到抑制，-logIC50 值约为 3.8。
T22838	hemagglutinin (332-340) [Influenza A virus]	Others	Others
	Influenza hemagglutinin is a type of hemagglutinin found on the surface of the influenza viruses. It is an antigenic glycoprotein. It is responsible for binding the virus to the cell that is being infected. Influenza hemagglutinin proteins bind to cells w

化合物

Cefmetazole sodium

Cat.No: T1070

Synonym: 头孢美唑钠,Sodium cefmetazole

Target: Antibacterial, Antibiotic

SulfadiMethoxine sodium

Cat.No: T8133

Target: Anti-infection, Antibacterial, Antibiotic

Sulfadimethoxine

Cat.No: T1078

Synonym: Sulphadimethoxine,磺胺二甲氧嗪

Target: Antibacterial, Antibiotic

Cat.No: T0116

Target: DNA gyrase, Antibacterial, Antibiotic

Sitafloxacin Hydrate

Cat.No: T6349

Synonym: 西他沙星水合物,DU-6859a,DU6859a hydrate

Target: Antibacterial, Antibiotic

2′-Deoxy-2′-fluoroguanosine

Cat.No: T38236

Target: Nucleoside Antimetabolite/Analog, Influenza Virus

Cat.No: T14369

Target: ROR

Cefaclor monohydrate

Cat.No: T1495

Synonym: Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor

Target: Antibacterial, Antibiotic

Oxolamine citrate

Cat.No: T0768

Synonym: 柠檬酸奥索拉明,AF-438 citrate,SKF-9976 citrate

Target: Others

Cat.No: T6436

Synonym: Panoral,Kefral,Cefaclorum,头孢克洛

Target: Others, Antibacterial, Antibiotic

Cat.No: T0284

Synonym: guaiacolsulfonate,愈创木酚磺酸钾

Target: Others, Antibacterial

Cat.No: T19794

Synonym: 替马沙星,Omniflox

Target: Antibiotic

Fenspiride hydrochloride

Cat.No: T0383

Synonym: Fenspiride HCl,Pneumorel,Fluiden,Decaspiride,盐酸芬司必利

Target: Adrenergic Receptor, PDE, Histamine Receptor

Cat.No: T10872L

Target: 5-HT Receptor

Cat.No: T8134

Target: Antibacterial, Antibiotic

Ambroxol hydrochloride

Cat.No: T6234

Synonym: Mucosolvan,Mucoangin,盐酸氨溴索,Ambroxol HCl

Target: Sodium Channel, Autophagy

Cat.No: T0920

Synonym: 氨溴索,氨溴索碱,Ambroxolum,NA-872

Target: P450, Autophagy

Cefetamet Hydrochloride

Cat.No: T26974

Synonym: Cefetamet HCl,Cefetamet

Cat.No: T32770

Synonym: CV 664

Cefonicid (free base)

Cat.No: T68999

Cat.No: T33282

Synonym: UK-237101,UK-2371,UK 237101,UK 2371,UK2371

Cefonicid monosodium

Cat.No: T68817

Thiamphenicol glycinate hydrochloride

Cat.No: T72093

Synonym: 甲砜霉素甘氨酸酯盐酸盐

Dexbrompheniramine maleate

Cat.No: T31396

Synonym: D-Brompheniramine,Brompheniramine d-,Dexbrompheniraminum,Disophrol,Drixoral

Cat.No: T75274

Cat.No: T9901A-016

11-deoxy Prostaglandin E2

Cat.No: T38342

Synonym: 11-deoxy Prostaglandin E2

Dehydroandrographolide succinate potassium sodium salt

Cat.No: T40971

Cat.No: T64312

BMS-433771 dihydrochloride hydrate

Cat.No: T72105

Sitafloxacin hydrochloride

Cat.No: T75286

Lomefloxacin (aspartate)

Cat.No: T63214

Temafloxacin (hydrochloride)

Cat.No: T21677

Guaiacol Carbonate

Cat.No: T60493

Cat.No: T38458

Cat.No: T11819

Synonym: 拉库沙星,KRP-AM1977X

Target: Others

Sitafloxacin monohydrate

Cat.No: T75287

Cat.No: T60417

hemagglutinin (332-340) [Influenza A virus]

Cat.No: T22838

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4984	Cefozopran hydrochloride SCE-2787 hydrochloride	Antifungal	Microbiology/Virology
	Cefozopran hydrochloride (SCE-2787 hydrochloride) 是一种半合成的非肠道头孢菌素。它是一种广谱抗菌抗生素，能抑制大多数革兰氏阴性和革兰氏阳性菌。
T1134	Clofoctol 叔辛酚氯,氯福克酚	Antibacterial; Antibiotic	Microbiology/Virology
	Clofoctol 是一种抗生素,，可研究革兰氏阳性菌感染。它仅对革兰氏阳性菌起作用, 可渗透入人类肺组织。
T2S0257	Dehydroandrographolide succinate	Others; Influenza Virus	Microbiology/Virology; Others
	Dehydroandrographolide succinate 是从中药穿心莲中提取的一种天然产物，具有免疫刺激、抗感染和抗炎作用，有潜力研究病毒性肺炎和病毒性上呼吸道感染。
T6567	Levofloxacin Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin	Topoisomerase; Antibacterial; Antibiotic	DNA Damage/DNA Repair; Microbiology/Virology
	Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素，有抑制细菌DNA 旋转酶的超螺旋活性的作用，能阻止DNA 复制。
TN5284	Sodium Houttuyfonate Houttuynin sodium bisulfite,新鱼腥草素钠	NF-κB; Antibacterial; Antifungal	Microbiology/Virology; NF-κB
	Sodium Houttuyfonate (Houttuynin sodium bisulfite) 是亚硫酸氢钠与鱼腥草结合而成的活性化合物，具有抗真菌、抗菌、抗炎和心血管保护活性，主要用于治疗化脓性皮肤感染、呼吸道感染，包括老年患者的肺炎和慢性支气管炎。

天然产物

Cefozopran hydrochloride

Cat.No: T4984

Synonym: SCE-2787 hydrochloride

Target: Antifungal

Cat.No: T1134

Synonym: 叔辛酚氯,氯福克酚

Target: Antibacterial, Antibiotic

Dehydroandrographolide succinate

Cat.No: T2S0257

Target: Others, Influenza Virus

Cat.No: T6567

Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Target: Topoisomerase, Antibacterial, Antibiotic

Sodium Houttuyfonate

Cat.No: TN5284

Synonym: Houttuynin sodium bisulfite,新鱼腥草素钠

Target: NF-κB, Antibacterial, Antifungal

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