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59

抑制剂 & 化合物

14

天然产物

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Cat. No. Product Name Target Signaling Pathways
T4507 Chlorphenesin

Adermykon,Chlorophenesin,Gecophen,氯苯甘醚

Antibacterial; Antifungal; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Chlorphenesin (Chlorophenesin) 是一种抗原相关免疫抑制剂,可抑制 IgE 介导的组胺释放。 它也用作抗真菌剂,用于许多眼保健化妆品中。
TP1763L Magainin 1 acetate

Antibacterial; Antibiotic; Antifungal Microbiology/Virology
Magainin 1 acetate 是一种抗菌肽。它对许多革兰氏阴性和革兰氏阳性细菌表现出抗生素活性。
T18885 3,6-Dichlorotrimellitic acid

Others Others
3,6-Dichlorotrimellitic acid 是一种制备多种二氯化荧光素和罗丹明 (如 TET 和 HEX) 的关键性前体试剂,这些氯化荧光素和罗丹明普遍用作寡核苷酸及 DNA 测序的标记。
T19506 PEG400

Others Others
PEG400 是一种强亲水性聚乙二醇,可作为多种物质的优良溶剂,广泛用于多种药物制剂中。
T6531 Heparin sodium salt

肝素钠,Sodium heparinate,Heparin sodium

Factor Xa; Thrombin; Autophagy Autophagy; Metabolism; Proteases/Proteasome
Heparin sodium salt (Sodium heparinate) 是一种抗凝剂,可与抗凝血酶 III 可逆地结合,使凝血酶因子 IIa 和 Xa 的失活速度加快,显着抑制外泌体-细胞相互作用。
T23601 ABC1183

ABC 1183,ABC-1183

GSK-3; CDK Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells
ABC1183是一种抑制GSK3α, GSK3β和CDK9的新型二氨基噻唑。ABC1183通过诱导G2/M 阻滞和改变GSK3、糖原合成酶、β-catenin 磷酸化和MCL1表达降低细胞存活率来抑制多种癌细胞株的生长,并具有口服活性。
T37185 D-(-)-3-Phosphoglyceric acid disodium

3-Phospho-D-glyceric acid disodium

Others Others
D-(-)-3-Phosphoglyceric acid disodium (3-Phospho-D-glyceric acid disodium) 是糖酵解、糖原合成以及丝氨酸、甘氨酸、苏氨酸生物合成等过程中的重要中间体,竞争性抑制酵母烯醇化酶 (enolase)。作为中间体它还在植物、真核细胞以及原核细胞许多的生物合成信号通路中发挥许多作用。
T36696 DMBA

7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzymes, including the cytochrome P450 (CYP450) isoform CYP1B1, as well as microsomal epoxide hydrolase (mEH), producing a variety of reactive metabolites that form DNA adductsin vivo, and it has been commonly used to induce tumor formation in various rodent models.2,3,1DMBA increase...
T39362 OG 488, acid

OG 488, a fluorescent pH indicator (acid), is widely used in biochemistry and neurosciences, offering numerous applications.
T33558 N,N'-Ethylenediamine disuccinic acid

L-Ethylenediaminedisuccinic acid,EDDS,EDSS

N, N'-Ethylenediamine disuccinic acid, as an aminopolycarboxylic acid, can be used as a biodegradable chelating agent similar to EDTA and used on a large scale in numerous applications.
T26121 Rooperol

Rooperol is a norlignan derivative with numerous biological activities including immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant activities. It is a novel p38α inhibitor.
T75662 Penicillin G benzathine tetrahydrate

Penicillin G benzathine tetrahydrate (Benzathine benzylpenicillin tetrahydrate) 为广谱抗生素,可抵抗多种细菌感染。
T21370 Amiodarone

Nexterone,胺碘酮,Amiodarona,Cordarone,Aratac,Amiodaronum

Amiodarone is categorized as a class III antiarrhythmic agent and prolongs phase 3 of the cardiac action potential. It also has numerous other effects, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV. Amiodarone chemic
TP2393 Neurotensin-related hexapeptide

Lant-6

Neurotensin-related hexapeptide exists in retinal ganglion cells and in their central projections in pigeons and may be utilized as a neuroactive substance by the central terminals of numerous retinal ganglion cells in birds.
T40558 Triclosan-methyl

Triclosan-methyl is a derivative of triclosan, which functions as a bactericide in various personal care products including toothpaste, shampoos, and soaps. Additionally, triclosan serves as a stabilizing agent in numerous detergents and cosmetics.
T26200 Somatostatin RC 102

Somatostatin RC102,Somatostatin-RC-102,Somatostatin RC-102

Somatostatin RC 102 is a peptide hormone. It regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones.
TD0053 Fluo-3, pentapotassium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentapotassium salt is most commonly used among the visible light-excitable calcium indicators.
T26573 AG311

AG 311,AG-311

AG311 is an inhibitor of complex I and hypoxia-induced HIF-1α stabilization. In vitro, AG311 induces rapid necrosis in numerous cancer cell lines. Within minutes, exposure to AG311 also results in mitochondrial depolarization, superoxide production, and i
T36365 KAPA (hydrochloride)

KAPA (hydrochloride),7-keto-8-Aminopelargomic Acid

Biotin is a growth factor that plays an important role in numerous reactions that are critical to microorganisms, plants, and animals. Biotin has a strong affinity for the protein avidin, a trait that has been utilized for many assay reporter applications. KAPA is a key intermediate in the biotin biosynthetic pathway.[1]
T22412 Quinacrine hydrochloride hydrate

Mepacrine Dihydrochloride Dihydrate,米帕林盐酸盐,Quinacrine Dihydrochloride Dihydrate

Others Others
Quinacrine, a dye of the acridine family, has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.
T74607 KRAS G12D inhibitor 15

KRAS G12D inhibitor 15 是一种有效的 KRAS G12D 抑制剂。KRAS G12D inhibitor 15 具有研究各种疾病或病症的潜力,例如癌症或癌症转移。
T6105 Phosphorylcholine chloride

phosphorylcholine,磷酸胆碱,Phosphocholine chloride

Others Others
Phosphorylcholine chloride 是一种构成细胞膜外层结构卵磷脂的组分,血液相容性较好。
T83402 2′,3′-cGMP triethylamine

Guanosine 2',3'-cyclic phosphate triethylamine

2',3'-cGMP triethylamine(Guanosine 2',3'-cyclic phosphate triethylamine)是一种活性化合物,常被用于多种科学研究领域。
T83494 [D-Trp8,Tyr11] Somatostatin

[D-Trp8,Tyr11] Somatostatin是一种somatostatin的类似物,后者是一种调节多种身体机能的激素。在该化合物中,DTrp8残基的加入可以提高其稳定性。
TD0052 Fluo-3, pentasodium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentasodium salt is most commonly used among the visible light-excitable calcium indicators.
TD0054 Fluo-3, pentaammonium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3, pentaammonium salt is most commonly used among the visible light-excitable calcium indicators.
T75309 R-(+)-Cotinine

R-(+)-Cotinine ((+)-Cotinine) 是一种尼古丁代谢物,在广泛的药理靶标中缺乏显着活性。R-(+)-Cotinine 可以增强人 α7nAChR 中的 Ach 诱发电流。
T63970 EZH2-IN-11

EZH2-IN-11 是 E2HZ 的有效抑制剂。其中 EZH2 的致癌活性已被各种不同癌症类型中的大量研究中证实。EZH2-IN-11 对癌症疾病表现出研究潜力。
T72755 GPR35 agonist 3

GPR35 agonist3,一种合成GPR35激动剂,EC50为1.4 μM。适用于胃癌、2型糖尿病、心血管疾病及免疫与周围神经系统研究。
T31995 GRC-17536

GRC17536,GRC 17536

GRC-17536 is an orally available, potent, and selective transient receptor potential anchor protein 1 (TRPA1) inhibitor that has been shown to be highly effective in the treatment of inflammation and neuropathic pain in animal models. The selectivity of G
T75359 Liperfluo

Liperfluo,作为铁死亡的标志物,是研究脂质过氧化在细胞病理生理过程中作用的有效荧光探针。它通过将脂质氢过氧化物还原为脂质醇,实现活细胞内脂质氢过氧化物的成像。
T37433 Erythromycin lactobionate

Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains.[1] It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s range from 0.015-2.0 mg/l).[2] Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can affect the metabolism of numerous clinically relevant medications.[3],[4] Erythromyc...
TD0049 Fluo-4, pentasodium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentasodium salt is an analog of fluo-3 with the t...
T35493 (±)10(11)-EpDPA

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in infla...
TD0050 Fluo-4, pentapotassium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentapotassium salt is an analog of fluo-3 with th...
T37432 Erythromycin A N-oxide

Erythromycin A N-oxide is a potential impurity found in commercial preparations of erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is effective against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l). Erythromycin is known to potently inhibit the cytochrome P450 isoform CYP3A4, which can af...
TD0051 Fluo-4, pentaammonium salt

Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and fluorescence microplate readers. Fluo-3 and Fluo-4 are most commonly used among the visible light-excitable calcium indicators. Fluo-4, pentaammonium salt is an analog of fluo-3 with the...
T73896 Glucose-6-phosphate dehydrogenase

Glucose-6-phosphate dehydrogenase 是戊糖磷酸途径的限速酶。Glucose-6-phosphate dehydrogenase 是抗氧化途径、一氧化氮合酶、NADPH 氧化酶、细胞色素 p450 等系统中 NADPH 的主要来源。Glucose-6-phosphate dehydrogenase 可用于糖尿病、醛固酮诱导的内皮功能障碍和癌症的研究。
T76770 Camidanlumab

Camidanlumab (HuMax-TAC) 作为一种CD25单克隆抗体,专门针对细胞表面CD25抗原,该抗原在多种血液肿瘤中过度表达,而在正常组织的表达则有限。因其特定目标,Camidanlumab被广泛应用于合成抗体活性分子偶联物(ADCs),旨在针对包括淋巴瘤和白血病在内的多种疾病进行研究。
T76943 Cepeginterferon alfa-2b

Cepeginterferon alfa-2b是一种聚乙二醇化干扰素, 其聚乙二醇基由分子量为20 kDa的PEG构成。该化合物广泛应用于丙型肝炎病毒(HCV)、真性红细胞增多症(PV)和原发性血小板增多症(ET)等疾病的研究中。
T73642 PD-1/PD-L1-IN 3 TFA

PD-1/PD-L1-IN 3 TFA,一大环肽类化合物,有效且选择性抑制PD-1/PD-L1与CD80/PD-L1相互作用。该化合物通过结合PD-L1,干扰其与PD-1和CD80的结合,具有分别为5.60 nM和7.04 nM的IC50值。适用于癌症及传染病等疾病研究。
T35986 CAY10512

The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activatio...
T35496 (±)13(14)-EpDPA

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)13(14)-EpDPA is a docosahexaenoic acid epoxygenase metabolite, derived via epoxidation of the 13,14-double bond of DHA. It has been detected in rat brain and spinal cord and is a preferred substrate for soluble epoxide hydrolase with a Km value of 3.2 μM. (±)13(14)-EpDPA demonstrates antihyperalgesic activity in inflammatory and neuropathic pain models. (±)13(14)-EpDPA and other epoxy m...
T73809 UDP-GalNAc disodium

UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium 是一种糖核苷酸,同时为EpsC115底物,其中EpsC115为exopolymeric substance (EPS) N端残基1-115缺失的突变体。此化合物充当多种N-乙酰半乳糖胺基转移酶的供体底物,这些酶专门负责将GalNAc从核苷酸糖转移至特定的糖或肽受体上。
T76194 PINT-87aa TFA

PINT-87aa TFA,一种含87个氨基酸的肽,由长链非编码RNA (LINC-PINT) 环状转录本编码,可与聚合酶相关因子复合物 (PAF1c) 直接作用,抑制多种癌基因转录延伸。在体外及体内有效抑制胶质母细胞瘤细胞增殖。
T74368 OKI-006

OKI-006 是一种有效的、具有口服活性的组蛋白脱乙酰酶 (HDAC) 抑制剂。OKI-006 是天然产物HDAC 抑制剂 largazole 的独特同系物。组蛋白去乙酰化酶 (HDAC) 在表观基因组调控中起关键作用,并且组蛋白乙酰化在许多人类癌症中失调。OKI-006 具有研究癌症疾病的潜力。
T76124 Acyl coenzyme A synthetase

Acyl coenzyme A synthetase (ACS),一种生化研究中常用的酶,主要通过两步硫酯化反应激活脂肪酸与辅酶A结合,形成酰基辅酶A。该过程为脂质代谢中的多种合成与分解代谢途径,以及参与TCA循环中的有氧呼吸提供了关键中间物。
T81490 PHI-101

PHI-101是口服FLT3抑制剂,在克服多耐药突变方面表现出高效。该化合物对FLT3的ITD或TKD单突变体表现出显著抑制作用,同时也能抑制包括双重(ITD/D835Y或ITD/F691L)和三重(ITD/D835Y/F691L)耐药突变。PHI-101在治疗复发或难治性急性髓系白血病(AML)的研究中显示出应用潜力。
T35970 4-hydroxy Nonenal Alkyne

4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid. It is considered a potential causal agent in numerous diseases, including chronic inflammation, neurodegenerative diseases, atherosclerosis, diabetes, and cancer, in part because it covalently modifies DNA and proteins resulting in genetic mutations and altered cell signaling, respectively. 4-HNE Alkyne is a form of 4-HNE with a term...
T78858 cGAS-IN-1

cGAS-IN-1(化合物C20)是一种黄酮类化合物,作为Cyclic GMP-AMP Synthase(cGAS)的抑制剂,其IC50分别为2.28 μM(针对人类cGAS)和1.44 μM(针对小鼠cGAS)。由于cGAS异常激活与众多免疫介导的炎症性疾病相关,cGAS-IN-1显示出了其抗炎潜力。

化合物

Chlorphenesin
Cat.No: T4507
Synonym: Adermykon,Chlorophenesin,Gecophen,氯苯甘醚
Target: Antibacterial, Antifungal, Histamine Receptor
Magainin 1 acetate
Cat.No: TP1763L
Synonym:
Target: Antibacterial, Antibiotic, Antifungal
3,6-Dichlorotrimellitic acid
Cat.No: T18885
Synonym:
Target: Others
PEG400
Cat.No: T19506
Synonym:
Target: Others
Heparin sodium salt
Cat.No: T6531
Synonym: 肝素钠,Sodium heparinate,Heparin sodium
Target: Factor Xa, Thrombin, Autophagy
ABC1183
Cat.No: T23601
Synonym: ABC 1183,ABC-1183
Target: GSK-3, CDK
D-(-)-3-Phosphoglyceric acid disodium
Cat.No: T37185
Synonym: 3-Phospho-D-glyceric acid disodium
Target: Others
DMBA
Cat.No: T36696
Synonym:
Target:
OG 488, acid
Cat.No: T39362
Synonym:
Target:
N,N'-Ethylenediamine disuccinic acid
Cat.No: T33558
Synonym: L-Ethylenediaminedisuccinic acid,EDDS,EDSS
Target:
Rooperol
Cat.No: T26121
Synonym:
Target:
Penicillin G benzathine tetrahydrate
Cat.No: T75662
Synonym:
Target:
Amiodarone
Cat.No: T21370
Synonym: Nexterone,胺碘酮,Amiodarona,Cordarone,Aratac,Amiodaronum
Target:
Neurotensin-related hexapeptide
Cat.No: TP2393
Synonym: Lant-6
Target:
Triclosan-methyl
Cat.No: T40558
Synonym:
Target:
Somatostatin RC 102
Cat.No: T26200
Synonym: Somatostatin RC102,Somatostatin-RC-102,Somatostatin RC-102
Target:
Fluo-3, pentapotassium salt
Cat.No: TD0053
Synonym:
Target:
AG311
Cat.No: T26573
Synonym: AG 311,AG-311
Target:
KAPA (hydrochloride)
Cat.No: T36365
Synonym: KAPA (hydrochloride),7-keto-8-Aminopelargomic Acid
Target:
Quinacrine hydrochloride hydrate
Cat.No: T22412
Synonym: Mepacrine Dihydrochloride Dihydrate,米帕林盐酸盐,Quinacrine Dihydrochloride Dihydrate
Target: Others
KRAS G12D inhibitor 15
Cat.No: T74607
Synonym:
Target:
Phosphorylcholine chloride
Cat.No: T6105
Synonym: phosphorylcholine,磷酸胆碱,Phosphocholine chloride
Target: Others
2′,3′-cGMP triethylamine
Cat.No: T83402
Synonym: Guanosine 2',3'-cyclic phosphate triethylamine
Target:
[D-Trp8,Tyr11] Somatostatin
Cat.No: T83494
Synonym:
Target:
Fluo-3, pentasodium salt
Cat.No: TD0052
Synonym:
Target:
Fluo-3, pentaammonium salt
Cat.No: TD0054
Synonym:
Target:
R-(+)-Cotinine
Cat.No: T75309
Synonym:
Target:
EZH2-IN-11
Cat.No: T63970
Synonym:
Target:
GPR35 agonist 3
Cat.No: T72755
Synonym:
Target:
GRC-17536
Cat.No: T31995
Synonym: GRC17536,GRC 17536
Target:
Liperfluo
Cat.No: T75359
Synonym:
Target:
Erythromycin lactobionate
Cat.No: T37433
Synonym:
Target:
Fluo-4, pentasodium salt
Cat.No: TD0049
Synonym:
Target:
(±)10(11)-EpDPA
Cat.No: T35493
Synonym:
Target:
Fluo-4, pentapotassium salt
Cat.No: TD0050
Synonym:
Target:
Erythromycin A N-oxide
Cat.No: T37432
Synonym:
Target:
Fluo-4, pentaammonium salt
Cat.No: TD0051
Synonym:
Target:
Glucose-6-phosphate dehydrogenase
Cat.No: T73896
Synonym:
Target:
Camidanlumab
Cat.No: T76770
Synonym:
Target:
Cepeginterferon alfa-2b
Cat.No: T76943
Synonym:
Target:
PD-1/PD-L1-IN 3 TFA
Cat.No: T73642
Synonym:
Target:
CAY10512
Cat.No: T35986
Synonym:
Target:
(±)13(14)-EpDPA
Cat.No: T35496
Synonym:
Target:
UDP-GalNAc disodium
Cat.No: T73809
Synonym:
Target:
PINT-87aa TFA
Cat.No: T76194
Synonym:
Target:
OKI-006
Cat.No: T74368
Synonym:
Target:
Acyl coenzyme A synthetase
Cat.No: T76124
Synonym:
Target:
PHI-101
Cat.No: T81490
Synonym:
Target:
4-hydroxy Nonenal Alkyne
Cat.No: T35970
Synonym:
Target:
cGAS-IN-1
Cat.No: T78858
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN2883 3',4'-Dimethoxyflavone

Others; PARP Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
3',4'-Dimethoxyflavone 是类黄酮化合物的参考标准,类黄酮化合物具有多种药用活性。
T5664 Bovine Serum Albumin

牛血清白蛋白,BSA,Bovine albumin,Albumin bovine serum,白蛋白

Others Others
Bovine Serum Albumin (BSA) 是一种由三个同源全 α 结构域组成的 583 个氨基酸的蛋白质,是一种球状蛋白,可用于多种生物化学实验中。
T5658 Adamantane

Others Others
Adamantane 是许多化合物的结构骨架,也是有机多面体化合物的物理化学和生物学特性,在制药工业中有实际应用。
T38815 Millepachine

Apoptosis Apoptosis
Millepachine 是分离自中草药Millettia pachycarpaBenth 的查尔酮,在体内外对多种人类癌细胞均显示出强大的抗增殖作用。
T1246 Bornyl acetate

乙酸冰片酯,Bornyl acetic ether,2-Camphanol acetate,乙酸龙脑酯,Isobornyl acetate

Apoptosis; IL Receptor Apoptosis; Immunology/Inflammation
Bornyl acetate (Isobornyl acetate) 是一种强效的芳香剂,是功效最强大的风味稀释因子之一,具有抗肿瘤活性。
T1609 NAD+

烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD

NADPH; Endogenous Metabolite Metabolism
NAD+ (β-Nicotinamide Adenine Dinucleotide) 即烟酰胺腺嘌呤二核苷酸,是转递氢离子的辅酶。
T2869 Emodin

Frangula emodin,大黄素

SARS-CoV; Casein Kinase; Autophagy Autophagy; Metabolism; Microbiology/Virology; Stem Cells
Emodin (Frangula emodin) 是蒽醌衍生物,有抗SARS-CoV 作用。它阻断 SARS 冠状病毒刺突蛋白和血管紧张素转化酶 2 的相互作用。它抑制酪蛋白激酶 2 ,具有抗炎和抗癌作用。它可改善饮食诱导的肥胖小鼠的代谢紊乱。
T4429 Rauwolscine hydrochloride

Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride

Adrenergic Receptor GPCR/G Protein; Neuroscience
Rauwolscine hydrochloride (Isoyohimbine hydrochloride) 是一种高选择性的 α2 adrenergic 受体拮抗剂,Ki=12 nM。
T3578 Pyridoxal phosphate

PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate

Reverse Transcriptase; Endogenous Metabolite Metabolism; Microbiology/Virology
Pyridoxal phosphate (Vitamin B6 phosphate) 是维生素 B6 的活性形式,可抑制逆转录酶活性,用于研究迟发性运动障碍症。
T4723 D-Tagatose

塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Others; Endogenous Metabolite Metabolism; Others
D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖,具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物,也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品,也是口香糖、果汁和饮料等食品中的低热量甜味剂。
T14196 Alternariol

Others Others
Alternariol (AOH), a mycotoxin synthesized by Alternaria species, displays numerous therapeutic and biological effects, including phytotoxic, cytotoxic, anti-HIV, anti-cancer, and anti-microbial properties. It functions by inhibiting the catalytic activity of topoisomerase I and II enzymes.
T78538 Fisetin quarterhydrate

Fisetin quarterhydrate是天然黄酮醇,在众多水果和蔬菜中存在,它展现了抗氧化、抗癌和神经保护等多重功效。
T78486 cis-Nerolidol

cis-Nerolidol,一种倍半萜醇,广泛存在于众多植物中,具抗氧化与抗菌活性,并能增强抗生素效果。
T81649 Notoginsenoside R3

Notoginsenoside R3为P. notoginseng的有效成分,具备多种生理作用,并可作为信号分子。该化合物亦用于心血管疾病研究中的传统中药。

天然产物

3',4'-Dimethoxyflavone
Cat.No: TN2883
Synonym:
Target: Others, PARP
Bovine Serum Albumin
Cat.No: T5664
Synonym: 牛血清白蛋白,BSA,Bovine albumin,Albumin bovine serum,白蛋白
Target: Others
Adamantane
Cat.No: T5658
Synonym:
Target: Others
Millepachine
Cat.No: T38815
Synonym:
Target: Apoptosis
Bornyl acetate
Cat.No: T1246
Synonym: 乙酸冰片酯,Bornyl acetic ether,2-Camphanol acetate,乙酸龙脑酯,Isobornyl acetate
Target: Apoptosis, IL Receptor
NAD+
Cat.No: T1609
Synonym: 烟酰胺腺嘌呤二核苷酸,Cozymase,煙酸胺,β-DPN,DPN,β-Nicotinamide Adenine Dinucleotide,β-NAD
Target: NADPH, Endogenous Metabolite
Emodin
Cat.No: T2869
Synonym: Frangula emodin,大黄素
Target: SARS-CoV, Casein Kinase, Autophagy
Rauwolscine hydrochloride
Cat.No: T4429
Synonym: Corynanthidine hydrochloride,盐酸育亨宾碱,萝芙素盐酸盐,α-Yohimbine hydrochloride,Isoyohimbine hydrochloride
Target: Adrenergic Receptor
Pyridoxal phosphate
Cat.No: T3578
Synonym: PLP,PAL-P,磷酸吡哆醛,pyridoxal 5'-phosphate,Pyridoxyl phosphate,Pyridoxal 5′-phosphate,Vitamin B6 phosphate
Target: Reverse Transcriptase, Endogenous Metabolite
D-Tagatose
Cat.No: T4723
Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos
Target: Others, Endogenous Metabolite
Alternariol
Cat.No: T14196
Synonym:
Target: Others
Fisetin quarterhydrate
Cat.No: T78538
Synonym:
Target:
cis-Nerolidol
Cat.No: T78486
Synonym:
Target:
Notoginsenoside R3
Cat.No: T81649
Synonym:
Target:
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