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83

抑制剂 & 化合物

25

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Cat. No. Product Name Target Signaling Pathways
T34744 Sulfo-NHS-LC-Biotin

long chain Sulfo NHS Biotin

Sulfo-NHS-LC-Biotin, or Sulfosuccinimidyl 6-(biotinamido) Hexanoate, is a long-chain water-soluble biotinylating agent that targets cell surface proteins and is reactive to primary amine groups.
T41323 Dihomo-γ-Linolenic acid methyl ester

Others Others
Dihomo-γ-Linolenic acid methyl ester 是 Dihomo-γ-Linolenic acid 的甲酯形式,Dihomo-γ-Linolenic acid 具有抗炎和抗增殖作用。
T9578 ELOVL1-IN-1

1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide

Others Others
ELOVL1-IN-1 (1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide) 是ELOVL1抑制剂,能够降低超长链脂肪酸的水平,可用于肾上腺脑白质营养不良的研究。
T20331 Sodium lauroyl glutamate

Hostapon CLG,Amisoft LS 11,Sodium N-lauroylglutamate,月桂酰谷氨酸钠,Acylglutamate LS-11

Others Others
Sodium lauroyl glutamate (Acylglutamate LS-11) 是一种氨基酸去污剂,可增加长链没食子酸烷基酯(如没食子酸烷基酯)的溶解度。
T3433 TUG-891

TUG 891,TUG891

GPR Endocrinology/Hormones; GPCR/G Protein
TUG-891 是一种选择性的长链游离脂肪酸受体 4 (FFA4/GPR120) 的激动剂。
T13036L Sulfosuccinimidyl oleate sodium

Sulfo-N-succinimidyl oleate sodium

Others Others
Sulfosuccinimidyl oleate sodium (Sulfo-N-succinimidyl oleate sodium) 是一种长链脂肪酸。它可以抑制脂肪酸转运到细胞中。它具有抗炎作用。
T37735 Stearoyl-L-carnitine chloride

C18 Carnitine,Stearoylcarnitine chloride

Stearoyl-L-carnitine chloride(Acylcarnitine C18:0) 是一种存在于小脑中的长链酰基肉碱,抑制 GlyT2 ,是研究脂代谢的重要组成部分。
T19210 Biotin LC hydrazide

Biotinamidocaproyl hydrazide,Biotin Aminocaproyl Hydrazide,(+)-Biotinamidohexanoic Acid hydrazide,BACH

Others Others
Biotin LC hydrazide (BACH) 是一种长链蛋白的修饰试剂。 生物素 LC 酰肼可转化高碘酸盐氧化的糖蛋白,可用于靶向糖蛋白和聚糖。
T23550 YM-750

YM 750

Acyltransferase Metabolism
YM-750 是一种有效的酰基:胆固醇酰基转移酶(ACAT)抑制剂,IC50为0.18 μM。
T60219 ELOVL1-IN-3 

Others Others
ELOVL1-IN-3 是一种有效且具有口服活性的超长链脂肪酸 1 (ELOVL1) 酶延长抑制剂。ELOVL1-IN-3 是研究肾上腺脑白质营养不良 (ALD) 的有用工具。
T19061 Sulfo-NHS-SS-Biotin sodium

Sulfosuccinimidyl 3-[[2-(biotinamido)ethyl]dithio]propionate,Sulfo-NThiol-SS-biotin,Sulfo-NHS-SS-Biotin (sodium),Sulfo-NHS-SS-Biotin

Others Others
Sulfo-NHS-SS-Biotin sodium (Sulfosuccinimidyl 3-[[2-(biotinamido)ethyl]dithio]propionate) 是一种长链可裂解和细胞无渗透的胺类活性生物素化 (biotinylation) 试剂。Sulfo-NHS-SS-Biotin sodium 可用于细胞表面蛋白 (cell-surface protein) 的标记和纯化。
T0988 Trimetazidine dihydrochloride

盐酸曲美他嗪,Yoshimilon,Kyurinett,Vastarel F

Autophagy; Fatty Acid Synthase Autophagy; Metabolism
Trimetazidine dihydrochloride (Vastarel F) 是细胞保护性抗缺血剂,也用作缺血性心脏病或心绞痛的血管扩张剂,具有抗氧化,抗炎,抗伤害和胃保护作用。它可通过抑制脂肪酸代谢提高心肌葡萄糖利用率。
T37563 C22 Ceramide (d18:1/22:0)

Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0)

C22 Ceramide (d18:1/22:0) (C22 Ceramide) 是一种从海绵Haliclona koremella 中分离出含有山嵛酸的长链神经酰胺,是一种内源性生物活性鞘脂。C22 Ceramide (d18:1/22:0) 可特异性抑制MCSR,降低离体大鼠肝线粒体和脂质体中 C16-神经酰胺通道的形成。
T60627 ELOVL1-IN-2

Others Others
ELOVL1-IN-2 是一种被称为极长链脂肪酸 1 (ELOVL1) 酶延长抑制剂的化合物,对 ELOVL1 表现出微弱的抑制作用(IC50 为 21 μM),并在原代细胞中表现出中等效力。对 HEK293 C26 细胞进行测定(IC50 为 6.7 μM)[1]。
T14878 CAY10566

Dehydrogenase; Stearoyl-CoA Desaturase (SCD) Metabolism
CAY10566 是选择性的、口服具有活性的硬脂酰辅酶 A 去饱和酶 1 抑制剂,在小鼠和人酶测定中IC50分别为 4.5 和 26 nM。它具有显著的细胞活性,可阻断 HepG2 细胞中饱和长链脂肪酸-CoAs (LCFA-CoAs) 向单不饱和 LCFA-CoAs 的转化 。
T4309 CIL56

CA3

Ferroptosis; ROS Apoptosis; Immunology/Inflammation
CIL56 (CA3) 是一种选择性铁死亡诱导剂,可通过产生铁依赖性活性氧来诱导细胞铁死亡。
T6446 Clevudine

L-FMAU,克拉夫定,Levovir

HBV; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
Clevudine (Levovir) 是一种非自然 L-构型的核苷类似物,是一种与聚合酶结合的非竞争性抑制剂,具有较强的抗 HBV 活性,半衰期长,毒性低的特点。
TP1930L1 Spexin acetate(1370290-58-6 free base)

Neuropeptide Y Receptor GPCR/G Protein; Neuroscience
Spexin acetate(1370290-58-6 free base) 是一种有效的甘丙肽受体 2/3 (GAL2/GAL3) 激动剂(EC50 值分别为 45.7 和 112.2 nM)。对甘丙肽受体 1 没有显着的活性。抑制脂肪细胞对长链脂肪酸的摄取并减少饮食诱导的肥胖小鼠和大鼠的食物消耗。减少金鱼的 LH 分泌。在体内表现出抗焦虑作用。
T35666 PRGL493

Others Others
PRGL493为高效、选择性的长链酰基辅酶a合成酶4 (ACSL4) 抑制剂,能在乳腺和前列腺细胞以及动物模型中抑制细胞增殖和肿瘤生长,主要应用于癌症研究。
T22444 Trimetazidine

Others Others
Trimetazidine, an anti-ischemic (anti-anginal) metabolic agent, could improve myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose
T33870 Palmitoyllactic acid

Lactic acid,palmitate

Palmitoyllactic acid is a long-chain fatty acid.
T68692 Palmoxirate sodium hydrate

Palmoxirate sodium hydrate is a potent inhibitor of long-chain fatty acid oxidation.
T71337 AJ-108235

AJ-108235 is a novel inhibitor of long chain fatty acid elongase 6 (ELOVL6).
T19196 Arachidonyl alcohol

Others Others
Arachidonyl alcohol, a long-chain primary fatty alcohol, serves as a substrate for synthesizing various ether lipids with beneficial functions.
T13917 tCFA15

Others Others
tCFA15, a trimethyl cyclohexenonic long-chain fatty alcohol with a 15-carbon atom side chain, may regulate Notch signaling and promote neuronal differentiation.
T71948 Flufenacet

Flufenacet is a herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis.
T34713 Stearyl tyrosine

Stearyl-tyrosine,Stearyltyrosine

Stearyl tyrosine is an immunoadjuvants, long-chain stearyl ester of amino acids and peptides.
T68618 S-(-)-Etomoxir

S-(-)-Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1) -- a molecule required for the oxidation of long-chain acyl CoA esters.
T16036 Melinamide

甲亚油酰胺,AC 223,DL-N-(α-Methylbenzyl)linoleamide

Others Others
Melinamide is an amide derivative of an unsaturated long-chain fatty acid and also is an inhibitor of cholesterol absorption (IC50: 20.9 μM).
T36050 Linoleoyl-L-carnitine (chloride)

Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg/kg) administration of isoniazid in mice.
T69240 Pyroxasulfone

Pyroxasulfone is an inhibitor of very-long-chain fatty acid biosynthesis. Pyroxasulfone is used to control grass weed species in pre-emergence in major field crops.
T37337 N-3-oxo-hexadecanoyl-L-Homoserine lactone

N-3-oxo-hexadecanoyl-L-Homoserine lactone is an unusual, substituted, long-chain N-acyl-homoserine lactone (AHL) produced by some bacteria, including strains of Agrobacterium vitis and Pseudomonas. Like other AHLs, this C16-containing form is thought to be involved in quorum sensing. Substituted, long-chain AHLs, including N-3-oxo-tetradecanoyl-L-homoserine lactone , prime for systemic acquired resistance to pathogen attack in plants.
T18049 Ibrutinib-biotin

Others Others
Ibrutinib-biotin is a probe that consists of Ibrutinib linked to biotin via a long chain linker, has an IC50 of 0.755-1.02 nM for BTK.
T40782 Metazachlor

Metazachlor, a member of the chloroacetamide class of herbicides, acts as a long chain fatty acid synthesis inhibitor. It exerts an influence on cell division and tissue differentiation in germinating and emerging weed species.
T20530 Cycloate

HSDB 1712,R-2063,HSDB-1712,Etsan,R 2063,R2063

Cycloate is a herbicide. It inhibits the biosynthesis of very-long-chain fatty acids, which is the essential constituents of plant suberin and waxes. Fatty acids also serve as precursors of aliphatic carbon chains in resorcinolic lipids.
T37245 Palmitoyl-D-carnitine (chloride)

Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palmitoylcarnitine synthesis by erythrocyte membranes.
T30797 Ceramide 1 A

Linoleoyloxyheptacosanoyl-C18-phytosphingosine

Ceramide 1 A 是一种蜡状脂质化合物,是顶端皮肤层的脂质。它具有特殊的分子结构,因为它含有一种与长链ω-羟基酸相连的亚油酸。
T13203 Trimetazidine-N-oxide

Others Others
Trimetazidine-N-oxide is the major active metabolite of Trimetazidine. Trimetazidine is a selective long-chain inhibitor of 3-ketoyl coenzyme A thiolase (IC50: 75 nM), has anti-oxidant, anti-inflammatory, antinociceptive, and gastroprotective properties.
T40980 Palmitic acid-13C2

Palmitic acid-13C2

Palmitic acid-13C2 is the 13C-labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.
T37623 1,2-Dierucoyl-sn-glycero-3-PC

1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP).
T37461 EOS (d18:1/32:1/18:2)

EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid . The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the ver...
T39423 Palmitic acid-13C sodium

Sodium palmitate-13C is the 13C-labeled variant of palmitic acid, a long-chain saturated fatty acid prevalent in animals and plants. This compound has been shown to induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer-binding protein homologous protein (CHOP) in mouse granulosa cells.
T37371 4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.
T73778 cis-5-Tetradecenoic acid

cis-5-Tetradecenoic acid,一种存在于血液中的内源性代谢物,主要用于研究长链3羟酰基CoA脱氢酶缺乏症。
T37679 3-hydroxy Palmitic Acid

3-hydroxy Palmitic acid is a form of the 16:0 lipid palmitic acid . The lipid A part of lipopolysaccharides contain various 3-hydroxy fatty acids, making oxylipins such as 3-hydroxy palmitic acid useful as chemical markers of endotoxins. In R. solanacearum, 3-hydroxy palmitic acid is converted by an S-adenosyl methionine-dependent methyltransferase to 3-hydroxy palmitic acid methyl ester, which acts as a quorum sensing signal molecule for post-transcriptional modulation of genes involved in viru...
T40899 2-Chloroacetamide

2-Chloroacetamide is a versatile chemical compound with several applications. Acting as a preservative and herbicide, it effectively controls vegetation in upland areas as well as paddy fields. Additionally, it serves as a biocide in diverse sectors including agriculture, glues, paints, and coatings. Notably, 2-Chloroacetamide demonstrates inhibitory properties toward very-long-chain fatty acid elongase, further highlighting its multifaceted nature.
T37299 L-Palmitoylcarnitine chloride

Palmitoyl-L-carnitine is a naturally occurring long-chain acylcarnitine and the L-enantiomer of palmitoyl-DL-carnitine . In cells, palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It also inhibits lecithin:cholesterol acyltransferase activity in rat, but not human, plasma when used at a concentration of 500 μM. In vivo, palmitoyl-L-carnitine increases intestinal absorption of the ant...
T37680 3-hydroxy Palmitic Acid methyl ester

3-hydroxy Palmitic acid methyl ester (3-hydroxy PAME) is an esterized long-chain fatty acid involved in quorum sensing in R. solanacearum, a bacteria that causes lethal wilting in plants. 3-hydroxy-PAME (175 nM) increases levels of PhcA-regulated virulence factors, greater than 20-, 30-, and 25-fold for EPS I, EGL, and PME, respectively, in the AW1-83 strain of R. solanacearum.
T35691 Myristoyl Coenzyme A (hydrate)

Myristoyl coenzyme A (myristoyl-CoA) is a derivative of CoA that contains the long-chain fatty acid myristic acid . It is a substrate for N-myristoyltransferase during myristoylation, a process that adds a myristoyl group to proteins either during translation to modify protein activity or post-translationally in apoptotic cells. It is also a substrate in the de novo synthesis of phosphatidylinositol .
T76002 Spexin TFA

Spexin TFA, a potent agonist for galanin receptor 2/3 (GAL2/GAL3) with EC50 values of 45.7 and 112.2 nM respectively, shows no significant activity towards galanin receptor 1. As an endogenous peptide promoting satiety, it reduces long chain fatty acid uptake by adipocytes and lowers food consumption in diet-induced obese mice and rats. Additionally, it moderates LH secretion in goldfish and demonstrates anxiolytic effects in vivo.

化合物

Sulfo-NHS-LC-Biotin
Cat.No: T34744
Synonym: long chain Sulfo NHS Biotin
Target:
Dihomo-γ-Linolenic acid methyl ester
Cat.No: T41323
Synonym:
Target: Others
ELOVL1-IN-1
Cat.No: T9578
Synonym: 1-(2-Fluorophenyl)-N-(1-(2-fluoropyridin-4-YL)-1H-pyrazol-3-YL)cyclopropane-1-carboxamide
Target: Others
Sodium lauroyl glutamate
Cat.No: T20331
Synonym: Hostapon CLG,Amisoft LS 11,Sodium N-lauroylglutamate,月桂酰谷氨酸钠,Acylglutamate LS-11
Target: Others
TUG-891
Cat.No: T3433
Synonym: TUG 891,TUG891
Target: GPR
Sulfosuccinimidyl oleate sodium
Cat.No: T13036L
Synonym: Sulfo-N-succinimidyl oleate sodium
Target: Others
Stearoyl-L-carnitine chloride
Cat.No: T37735
Synonym: C18 Carnitine,Stearoylcarnitine chloride
Target:
Biotin LC hydrazide
Cat.No: T19210
Synonym: Biotinamidocaproyl hydrazide,Biotin Aminocaproyl Hydrazide,(+)-Biotinamidohexanoic Acid hydrazide,BACH
Target: Others
YM-750
Cat.No: T23550
Synonym: YM 750
Target: Acyltransferase
ELOVL1-IN-3 
Cat.No: T60219
Synonym:
Target: Others
Sulfo-NHS-SS-Biotin sodium
Cat.No: T19061
Synonym: Sulfosuccinimidyl 3-[[2-(biotinamido)ethyl]dithio]propionate,Sulfo-NThiol-SS-biotin,Sulfo-NHS-SS-Biotin (sodium),Sulfo-NHS-SS-Biotin
Target: Others
Trimetazidine dihydrochloride
Cat.No: T0988
Synonym: 盐酸曲美他嗪,Yoshimilon,Kyurinett,Vastarel F
Target: Autophagy, Fatty Acid Synthase
C22 Ceramide (d18:1/22:0)
Cat.No: T37563
Synonym: Cer(d18:1/22:0),C22 Ceramide,Ceramide (d18:1/22:0)
Target:
ELOVL1-IN-2
Cat.No: T60627
Synonym:
Target: Others
CAY10566
Cat.No: T14878
Synonym:
Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)
CIL56
Cat.No: T4309
Synonym: CA3
Target: Ferroptosis, ROS
Clevudine
Cat.No: T6446
Synonym: L-FMAU,克拉夫定,Levovir
Target: HBV, DNA/RNA Synthesis
Spexin acetate(1370290-58-6 free base)
Cat.No: TP1930L1
Synonym:
Target: Neuropeptide Y Receptor
PRGL493
Cat.No: T35666
Synonym:
Target: Others
Trimetazidine
Cat.No: T22444
Synonym:
Target: Others
Palmitoyllactic acid
Cat.No: T33870
Synonym: Lactic acid,palmitate
Target:
Palmoxirate sodium hydrate
Cat.No: T68692
Synonym:
Target:
AJ-108235
Cat.No: T71337
Synonym:
Target:
Arachidonyl alcohol
Cat.No: T19196
Synonym:
Target: Others
tCFA15
Cat.No: T13917
Synonym:
Target: Others
Flufenacet
Cat.No: T71948
Synonym:
Target:
Stearyl tyrosine
Cat.No: T34713
Synonym: Stearyl-tyrosine,Stearyltyrosine
Target:
S-(-)-Etomoxir
Cat.No: T68618
Synonym:
Target:
Melinamide
Cat.No: T16036
Synonym: 甲亚油酰胺,AC 223,DL-N-(α-Methylbenzyl)linoleamide
Target: Others
Linoleoyl-L-carnitine (chloride)
Cat.No: T36050
Synonym:
Target:
Pyroxasulfone
Cat.No: T69240
Synonym:
Target:
N-3-oxo-hexadecanoyl-L-Homoserine lactone
Cat.No: T37337
Synonym:
Target:
Ibrutinib-biotin
Cat.No: T18049
Synonym:
Target: Others
Metazachlor
Cat.No: T40782
Synonym:
Target:
Cycloate
Cat.No: T20530
Synonym: HSDB 1712,R-2063,HSDB-1712,Etsan,R 2063,R2063
Target:
Palmitoyl-D-carnitine (chloride)
Cat.No: T37245
Synonym:
Target:
Ceramide 1 A
Cat.No: T30797
Synonym: Linoleoyloxyheptacosanoyl-C18-phytosphingosine
Target:
Trimetazidine-N-oxide
Cat.No: T13203
Synonym:
Target: Others
Palmitic acid-13C2
Cat.No: T40980
Synonym: Palmitic acid-13C2
Target:
1,2-Dierucoyl-sn-glycero-3-PC
Cat.No: T37623
Synonym:
Target:
EOS (d18:1/32:1/18:2)
Cat.No: T37461
Synonym:
Target:
Palmitic acid-13C sodium
Cat.No: T39423
Synonym:
Target:
4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic Acid
Cat.No: T37371
Synonym:
Target:
cis-5-Tetradecenoic acid
Cat.No: T73778
Synonym:
Target:
3-hydroxy Palmitic Acid
Cat.No: T37679
Synonym:
Target:
2-Chloroacetamide
Cat.No: T40899
Synonym:
Target:
L-Palmitoylcarnitine chloride
Cat.No: T37299
Synonym:
Target:
3-hydroxy Palmitic Acid methyl ester
Cat.No: T37680
Synonym:
Target:
Myristoyl Coenzyme A (hydrate)
Cat.No: T35691
Synonym:
Target:
Spexin TFA
Cat.No: T76002
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T12287 Octadecanedioic acid

Endogenous Metabolite Metabolism
Octadecanedioic acid 是内源性代谢物的一种,是一种长链二羧酸,曾在雷氏综合征的血清游离脂肪酸中被发现。
T5567 Tetradecanedioic acid

十四烷二酸,Tetradecanedicarboxylate

Others; Endogenous Metabolite Metabolism; Others
Tetradecanedioic acid (Tetradecanedicarboxylate) 是一种长链脂肪酸,属于内源性代谢物的一种。它能够作为有机阴离子转运多肽介导的药物-药物相互作用的候选生物标志物。
T5368 Eicosapentaenoic Acid

Histone Demethylase; Others; Endogenous Metabolite Chromatin/Epigenetic; Metabolism; Others
Eicosapentaenoic Acid 是一种 ω-3 脂肪酸。
T17048 Tetradecanoylcarnitine

L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine

Endogenous Metabolite Metabolism
Tetradecanoylcarnitine (L-Myristoylcarnitine) 是一种酰基肉碱,参与长链脂肪酸的β-氧化,是极长链酰辅酶A脱氢酶缺乏症的一种潜在标记物。
T8111 Triacontanoic Acid

蜂花酸,Melissic acid A

Others Others
Triacontanoic Acid (Melissic acid A) 是一种超长链脂肪酸。
T8271 10Z-Nonadecenoic acid

Endogenous Metabolite Metabolism
10Z-Nonadecenoic acid 是一种长链脂肪酸,具有抗肿瘤特性。
T8285 Methyl tricosanoate

Others Others
Methyl tricosanoate 是一种长链脂肪酸化合物,存在于各种抗微生物剂和抗菌剂中。
T8192 Pentacosanoic acid

Others; Endogenous Metabolite Metabolism; Others
Pentacosanoic acid 是戊酸的共轭酸,是 25 碳长链饱和脂肪酸。
T5942 Docosanoic acid

Behenic Acid,山嵛酸

DNA/RNA Synthesis; Endogenous Metabolite Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Docosanoic acid (Behenic Acid) 是一种较难吸收的饱和脂肪酸,能提高人类胆固醇水平。
T4944 Nervonic acid

cis-15-Tetracosenoic acid,神经酸,Selacholeic acid

Endogenous Metabolite Metabolism
Nervonic acid (Selacholeic acid) 是在髓磷脂生物合成中很重要的单不饱和脂肪酸。
T7095 Hexacosanoic acid

二十六酸,Cerotic acid

Endogenous Metabolite Metabolism
Hexacosanoic acid 是长链脂肪酸,与多种疾病有关(如肾上腺脑白质营养不良,肾上腺髓鞘病和动脉粥样硬化)。
T40637 Gondoic acid

cis-11-Eicosenoicacid,顺-11-二十碳烯酸

Others Others
Gondoic acid (cis-11-Eicosenoicacid) (cis-11-Eicosenoic acid) 在多种植物油和坚果中可以发现的一种单不饱和长链脂肪酸。[1]
T4867 Erucic acid

Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid

PI3K; Endogenous Metabolite Metabolism; PI3K/Akt/mTOR signaling
Erucic acid (13(Z)-Docosenoic Acid) 是单不饱和脂肪酸,分离自萝卜的种子。Erucic acid 可以容易地穿过血脑屏障,使大脑中长链脂肪酸的积累正常化。Erucic acid 能够改善认知障碍并有效预防痴呆。
T4903 Heptadecanoic acid

Others; Endogenous Metabolite Metabolism; Others
Heptadecanoic acid 是奇链饱和脂肪酸,与一些疾病(如冠心病、糖尿病前期和 2 型糖尿病以及多发性硬化症)有关。
T19180 Adrenic Acid

二十二碳四烯酸,廿二碳四烯酸,cis-7,10,13,16-Docosatetraenoic acid

Endogenous Metabolite Metabolism
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) 是一种天然的多不饱和脂肪酸,主要存在于肾上腺,肾脏,大脑和脉管系统中。Adrenic Acid 能够调节肾上腺皮质血管的血管紧张度。Adrenic Acid 也是非酒精性脂肪肝疾病的炎症增强剂。
T37886 1-Heptadecanol

Antibacterial Microbiology/Virology
1-Heptadecanol 是分离自Solena amplexicaulis 的长链伯醇,显示出抗菌活性。
T0846 L-Carnitine

L(-)-Carnitine,Levocarnitine,左旋肉碱

Endogenous Metabolite; Fatty Acid Synthase Metabolism
L-Carnitine (L(-)-Carnitine) 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。
T4855 Tricosanoic acid

Tricosan-1-oic acid,二十三烷酸

Endogenous Metabolite Metabolism
Tricosanoic acid (Tricosan-1-oic acid) 是毛发生长激活剂,是长链脂肪酸。
T19504 Paullinic acid

Others Others
Paullinic acid is a long-chain fatty acid that has been detected in multiple biofluids.
T13199 Triacsin C

WS 1228A,FR 900190

Others Others
Triacsin C, from Streptomyces aureofaciens, is a natural intracellular long-chain inhibitor of acyl-CoA synthetases (ACSL).
TN6528 Butyrospermol

Others Others
Butyrospermol 是一种从乳木果(大戟属植物)中提取的protolimonoid,是首次从天然产物中发现的长链脂肪酸酯,具有拒食和抗肿瘤活性。
T8011 1,2-dioleoyl-sn-glycero-3-phosphocholine

二油酰磷脂酰胆碱,DOPC

Others Others
1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 是磷脂的一种,在胶束,脂质体和其他类型的人工膜的生成中通常单独使用或与其他组分一起使用。
T38331 Commendamide

Commendamide is a natural bacterial product that was discovered in a screen for commensal bacteria effector genes (Cbegs). Cbeg12 is a bacterial effector gene that encodes for its production. Commendamide is structurally similar to long-chain N-acyl-amides, which commonly signal, in mammals, through G protein-coupled receptors. Commendamide activates GPR132 (also known as G2A) with an EC50 value of 11.8 μM.
T73764 L-Palmitoylcarnitine TFA

L-Palmitoylcarnitine TFA 是一种长链酰基肉碱和脂肪酸代谢产物,在缺血期间积聚于肌膜并扰乱膜脂环境。L-Palmitoylcarnitine TFA 通过与Kir6.2的相互作用抑制KATP 通道活性,而不影响单通道电导。
T72152 Eicosapentaenoic Acid sodium

二十碳五烯酸钠盐,Timnodonic acid sodium,EPA sodium

Eicosapentaenoic Acid (EPA) sodium 为口服活性 ω-3 长链多不饱和脂肪酸 (ω-3 LC-PUFAs)。其通过DNA去甲基化,促进肿瘤抑制基因CCAAT/增强子结合蛋白δ (C/EBPδ)的重新表达,并通过H-RAS内含子1 CpG岛的去甲基化,激活U937白血病细胞中RAS/ERK/C/EBPβ途径。此外,该化合物能够促进血管平滑肌细胞松弛和血管舒张。

天然产物

Octadecanedioic acid
Cat.No: T12287
Synonym:
Target: Endogenous Metabolite
Tetradecanedioic acid
Cat.No: T5567
Synonym: 十四烷二酸,Tetradecanedicarboxylate
Target: Others, Endogenous Metabolite
Eicosapentaenoic Acid
Cat.No: T5368
Synonym:
Target: Histone Demethylase, Others, Endogenous Metabolite
Tetradecanoylcarnitine
Cat.No: T17048
Synonym: L-Myristoylcarnitine,Myristoyl-L-(-)-carnitine
Target: Endogenous Metabolite
Triacontanoic Acid
Cat.No: T8111
Synonym: 蜂花酸,Melissic acid A
Target: Others
10Z-Nonadecenoic acid
Cat.No: T8271
Synonym:
Target: Endogenous Metabolite
Methyl tricosanoate
Cat.No: T8285
Synonym:
Target: Others
Pentacosanoic acid
Cat.No: T8192
Synonym:
Target: Others, Endogenous Metabolite
Docosanoic acid
Cat.No: T5942
Synonym: Behenic Acid,山嵛酸
Target: DNA/RNA Synthesis, Endogenous Metabolite
Nervonic acid
Cat.No: T4944
Synonym: cis-15-Tetracosenoic acid,神经酸,Selacholeic acid
Target: Endogenous Metabolite
Hexacosanoic acid
Cat.No: T7095
Synonym: 二十六酸,Cerotic acid
Target: Endogenous Metabolite
Gondoic acid
Cat.No: T40637
Synonym: cis-11-Eicosenoicacid,顺-11-二十碳烯酸
Target: Others
Erucic acid
Cat.No: T4867
Synonym: Prifac 2990,芥酸,13(Z)-Docosenoic Acid,cis-13-docosenoic acid
Target: PI3K, Endogenous Metabolite
Heptadecanoic acid
Cat.No: T4903
Synonym:
Target: Others, Endogenous Metabolite
Adrenic Acid
Cat.No: T19180
Synonym: 二十二碳四烯酸,廿二碳四烯酸,cis-7,10,13,16-Docosatetraenoic acid
Target: Endogenous Metabolite
1-Heptadecanol
Cat.No: T37886
Synonym:
Target: Antibacterial
L-Carnitine
Cat.No: T0846
Synonym: L(-)-Carnitine,Levocarnitine,左旋肉碱
Target: Endogenous Metabolite, Fatty Acid Synthase
Tricosanoic acid
Cat.No: T4855
Synonym: Tricosan-1-oic acid,二十三烷酸
Target: Endogenous Metabolite
Paullinic acid
Cat.No: T19504
Synonym:
Target: Others
Triacsin C
Cat.No: T13199
Synonym: WS 1228A,FR 900190
Target: Others
Butyrospermol
Cat.No: TN6528
Synonym:
Target: Others
1,2-dioleoyl-sn-glycero-3-phosphocholine
Cat.No: T8011
Synonym: 二油酰磷脂酰胆碱,DOPC
Target: Others
Commendamide
Cat.No: T38331
Synonym:
Target:
L-Palmitoylcarnitine TFA
Cat.No: T73764
Synonym:
Target:
Eicosapentaenoic Acid sodium
Cat.No: T72152
Synonym: 二十碳五烯酸钠盐,Timnodonic acid sodium,EPA sodium
Target:
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