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140

抑制剂 & 化合物

27

天然产物

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Cat. No. Product Name Target Signaling Pathways
T28357 PET-16

PET16,PET 16

PET-16 is a HSP70 inhibitor.
T23252 Rp-8-Br-PET-cGMPS

Others Others
cGMP-dependent protein kinase (PKG) inhibitor
T79577 CB2 PET Radioligand 1

Cannabinoid Receptor GPCR/G Protein
CB2PET Radioligand 1 (compound [18F]9) 作为hCB2靶向的PET Radioligand (Ki=7.7 nM),采用Cu介导的18F-氟化方法制备,并在小鼠神经炎症模型中展现了高脑摄取率。
T8637 DMNB

6-Nitroveratraldehyde,6-硝基藜芦醛

DNA-PK DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
DMNB (6-Nitroveratraldehyde) 可用于合成no-carrier-added 6-[18F]fluoro-L-DOPA (6-FDOPA)。它可用于研究多巴胺能系统的PET
T17842 DOTA-​NHS-​ester

Others Others
DOTA-NHS-ester 是 affibody 分子的接头,应用于小动物 PET、SPECT 和 CT。 它可用于标记放射治疗剂或成像探针以检测肿瘤。
T7196 HG-10-102-01

[4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮

LRRK2 Autophagy
HG-10-102-01 是富含亮氨酸重复激酶 2 和突变型G2019S 抑制剂,IC50分别为20.3 nM 和3.2 nM。
T76890 Petosemtamab

MCLA 158

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Petosemtamab (MCLA 158) 是一种高效的抗 EGFR (Kd: 0.22 nM) 和抗 LGR5 (Kd: 0.86 nM) 单克隆抗体。Petosemtamab 促使 LGR5+ 癌细胞中的 EGFR 信号传导中断和受体分解。Petosemtamab 可用于头颈部鳞状细胞癌 (HNSCC)、转移性结直肠癌 (CRC) 等实体瘤的研究。
T31648 Epetirimod

S 30563,S-30563,S30563

Antiviral Immunology/Inflammation
Epetirimod (S-30563) 是一种小分子免疫调节剂,具有抗肿瘤和抗感染活性,可用于研究乳头状瘤病毒感染。
T9409 Mesdopetam hemitartrate

IRL790 hemitartrate,1-​Propanamine, N-​[2-​[3-​fluoro-​5-​(methylsulfonyl)​phenoxy]​ethyl]​-​, (2R,​3R)​-​2,​3-​dihydroxybutanedioat​e (2:1)

Dopamine Receptor GPCR/G Protein; Neuroscience
Mesdopetam hemitartrate (IRL790 hemitartrate) 是一种多巴胺D3受体拮抗剂 (Ki=90 nM;IC50=9.8 μM),具有稳定精神运动的作用,可用于帕金森病的运动和精神并发症的研究。
T4045 Epetraborole hydrochloride

GSK2251052 hydrochloride

Antibacterial Microbiology/Virology
Epetraborole hydrochloride (GSK2251052 hydrochloride) 是一个新型 LeuRS 抑制剂,通过绑定 leucyl-tRNA 合成酶终端的腺苷核糖抑制蛋白合成,可研究 Gram-negative 细菌引起的感染。
T31614 Elpetrigine

GW-273293,JZP 4,JZP4,GW273293,JZP-4,GW 273293

Elpetrigine( GW 273293, JZP-4) is effective calcium and sodium channel blocker and is currently being evaluated in patients as an anticonvulsant and mood stabilizer.
T20818 Propetamphos

Deadmag,Safrotin S 200

Propetamphos, an organophosphate pesticide, can effectively control cockroaches, flies, mosquitoes, and other pests. It is also effective for cattle lice.
T126078 6-Dehydropetasol

6-Dehydropetasol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126078,CAS号为 129704-82-1。
T124020 Wampetin

Wampetin 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124020,CAS号为 87838-97-9。
T80379 Cyclopetide 1

Cyclopeptide 1 (Compound 1) 是抗菌肽,对 B. subtilis 表现出中等抑制效果,最小抑菌浓度 (MIC) 为 25 μg/mL。
T76255 Certepetide

Certepetide (CEND-1),即双功能环肽(a.k.a. iRGD),是一种具有穿透肿瘤功能的多肽。通过与α-V整联蛋白(alphav-integrins)的RGD motif相互作用,以及激活神经纤毛蛋白1(NRP-1),Certepetide能够将实体瘤微环境转化成临时的活性分子通道,从而在肿瘤中累积。该化合物在胰腺癌和其他实体瘤的研究中具有应用潜力。
T75924 APETx2 TFA

APETx2 TFA 是可来自Anthopleura elegantissima 的海葵肽,是选择性的、可逆的酸敏感的离子通道ASIC3 (acid-sensing ion channel)抑制剂,其 IC50值为 63 nM. APETx2 作用在ASIC3 通道外部。APETx2 TFA 能够逆转酸性诱导的炎症疼痛。
T37487 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
T20834 Dipropetryn

GS-16068,Cotofor,GS 16068,GS16068,Sancap

Dipropetryn, a triazine herbicide, is used to remove annual broadleaf weeds and gramineous weeds.
T71458 Epetraborole

Epetraborole is a potent and selective leucyl-tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens.
T124362 Petasinoside

Petasinoside 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124362。
T37486 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM.
T83718 5-FAM-LPETGG TFA

5-Carboxyfluorescein-LPETGG

5-FAM-LPETGG是一种荧光肽,由排序酶识别序列LPETGG与荧光标记5-carboxyfluorescein (5-FAM) 结合而成,其激发/发射最大值分别为492/518 nm。通过排序酶催化的转肽连接,它已被用于靶蛋白的特异性标记。
T124819 Isopetasol

Isopetasol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124819,CAS号为 469-67-0。
T126348 Nepetaside

Nepetaside 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T126348,CAS号为 114076-56-1。
T124576 Petasitenine

Petasitenine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124576。
T124054 Gossypetin 3-methylether

Gossypetin 3-methylether 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124054。
T37228 (±)8(9)-EpETE

Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±)17(18)-EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±)8(9)-EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epox...
T38559 Competence-Stimulating Peptide-2 (CSP-2)

Competence-Stimulating Peptide-2 (CSP-2) is a quorum sensing signal peptide synthesized by Streptococcus pneumoniae. ComD2, a compatible receptor of CSP-2, exhibits an EC 50 value of 50.7 nM.
T76603 HIV-IN petide

HIV-IN petide 是HIV-1蛋白酶 (Ki=50 nM) 的竞争性抑制剂。
T12413 PETCM

Others Others
PETCM is a caspase-3 activator and acts as an cytochrome c (cyto c)-dependent manner.
T37224 (±)5(6)-EpETE methyl ester

(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.(±) 5(6)-EpETE methyl ester is a chemically less reactive derivative of 5(6)-EpETE. The active free acid can be generated from the methyl ester by careful base hydrolysis. Epoxy eicosatetraenoic acids (EpETEs) are the epoxygenase metabolites of EPA. A number of vicinal diol metabolites of EpETEs have been detected in the plasma of patients on marine oil dietary supplementation, while in s...
T36215 17R(18S)-EpETE

17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases ...
T124565 Neopetasitenine

Neopetasitenine 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124565。
T40826 5(S)​-​HPETE

5(S)-Hydroperoxyeicosatetraenoic acid (5(S)-HpETE) is a monohydroperoxy polyunsaturated fatty acid (PUFA) generated by the enzymatic conversion of arachidonic acid via 5-lipoxygenase (5-LO). Subsequently, 5(S)-HpETE undergoes metabolism to form leukotriene A4 (LTA4), which serves as a pivotal intermediate in the synthesis of leukotrienes (LTs).
T33643 Nepetalactone

MD(sub 1) 84,MDI 84

Nepetalactone is found in the plant Nepeta parnassica and has high mosquito repellency properties.
T126232 Petiolin G

Petiolin G 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126232。
T27175 Dilopetine Citrate

E-6006 Citrate,E-6039,E6039,E 6039

Dilopetine Citrate, a tachykinin receptor modulator and a neurokinin receptor modulator, is used potentially for the treatment of depression.
TP1631 Competence-Stimulating Peptide-12261

Competence-Stimulating Peptide-12261, a sixteen peptide, is a fragment of competence-stimulating peptide.
TP2081 APETx2

Acid-sensing ion channel 3 (ASIC3) channel blocker (IC50 values are 63 and 175 nM for homomeric rat and human ASIC3 channels). Also inhibits NaV1.8 and NaV1.2 channels (IC50 values are 55 and 114 nM respectively). Demonstrates analgesic properties against
T37798 Petromyzonol

Petromyzonol is a tetrahydroxy stearol which serves as the primary spawning pheromone in adult sea lamprey. It is produced in the bile of sea lamprey larvae from the bile acid precursor allocholic acid. While the adult sea lamprey is relatively insensitive to petromyzonol itself, the C-24 sulfate ester (petromyzonol sulfate) is a pheromone and a spawning chemoattractant which can be detected at very low concentrations by lamprey olfactory chemoreceptors. Petromyzonol, petromyzonol sulfate, and a...
T37969 12(S)-HpETE

12(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of platelet or leukocyte 12-lipoxygenase (12-LO) on arachidonic acid. It activates human blood leukocyte 5-LO, resulting in the synthesis of 5(S)-HETE, leukotriene B4 (LTB4), and 5(S),12(S)-DiHETE. Rat lung metabolizes 12(S)-HpETE to 8,11,12- and 10,11,12-trihydroxyeicostrienoic acids. 12(S)-HpETE is the mediator of many biological functions, including induction of c-fos and c-jun, activation of AP-1, and e...
T131502 Apetalactone

Apetalactone 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131502。
T35943 15(S)-HpETE

15(S)-HpETE is a monohydroperoxy polyunsaturated fatty acid (PUFA) produced by the action of 15-lipoxygenase (15-LO) on arachidonic acid. It is either metabolized to 14,15-leukotriene A4 [1] or reduced to 15(S)-HETE by peroxidases.[2] [1] 15(S)-HpETE mediates a number of biological functions including the induction of c-fos and c-jun, and activation of AP-1. [3] 15(S)-HpETE inhibits prostacyclin synthesis in porcine aortic microsomes and bovine endothelial cells, and can cause the suicide inac...
T38828 Mesdopetam

IRL790

Mesdopetam (IRL790) is a dopamine D3 receptor antagonist with a Ki of 90 nM and an IC50 of 9.8 μM for the human recombinant D3 receptor. It exhibits psychomotor stabilizing properties and is utilized in the study of motor and psychiatric complications associated with Parkinson's disease.
T80380 Cyclopetide 2

Cyclopeptide 2 (Compound 2) 是中等活性抗菌肽,对B. subtilis的最小抑菌浓度(MIC)为50 μg/mL。
TP1631L Competence-Stimulating Peptide-12261 acetate

Competence-Stimulating Peptide-12261 acetate (1235882-91-3 free base)

Others Others
Competence-Stimulating Peptide-12261 acetate (1235882-91-3 free base) 是感觉刺激肽的片段,是一种抑制胚管 (GT) 形成的群体感应分子。
T37234 (±)14(15)-EpETE

EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty acids, produces epoxides such as (±)14(15)-EpETrE which are prime candidates for the actual active mediator. However, the CYP450 metabolites of eicosapentaenoic acid and docosahexaenoi...
T71168 Epetraborole R-Mandelate

Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor.
T16474 Petesicatib

Cysteine Protease Proteases/Proteasome
Petesicatib is an inhibitor of cathepsin S. Petesicatib used in the research of immune diseases.

化合物

PET-16
Cat.No: T28357
Synonym: PET16,PET 16
Target:
Rp-8-Br-PET-cGMPS
Cat.No: T23252
Synonym:
Target: Others
CB2 PET Radioligand 1
Cat.No: T79577
Synonym:
Target: Cannabinoid Receptor
DMNB
Cat.No: T8637
Synonym: 6-Nitroveratraldehyde,6-硝基藜芦醛
Target: DNA-PK
DOTA-​NHS-​ester
Cat.No: T17842
Synonym:
Target: Others
HG-10-102-01
Cat.No: T7196
Synonym: [4-[[5-氯-4-(甲基氨基)-2-嘧啶基]氨基]-3-甲氧基苯基]-4-吗啉基甲酮
Target: LRRK2
Petosemtamab
Cat.No: T76890
Synonym: MCLA 158
Target: EGFR
Epetirimod
Cat.No: T31648
Synonym: S 30563,S-30563,S30563
Target: Antiviral
Mesdopetam hemitartrate
Cat.No: T9409
Synonym: IRL790 hemitartrate,1-​Propanamine, N-​[2-​[3-​fluoro-​5-​(methylsulfonyl)​phenoxy]​ethyl]​-​, (2R,​3R)​-​2,​3-​dihydroxybutanedioat​e (2:1)
Target: Dopamine Receptor
Epetraborole hydrochloride
Cat.No: T4045
Synonym: GSK2251052 hydrochloride
Target: Antibacterial
Elpetrigine
Cat.No: T31614
Synonym: GW-273293,JZP 4,JZP4,GW273293,JZP-4,GW 273293
Target:
Propetamphos
Cat.No: T20818
Synonym: Deadmag,Safrotin S 200
Target:
6-Dehydropetasol
Cat.No: T126078
Synonym:
Target:
Wampetin
Cat.No: T124020
Synonym:
Target:
Cyclopetide 1
Cat.No: T80379
Synonym:
Target:
Certepetide
Cat.No: T76255
Synonym:
Target:
APETx2 TFA
Cat.No: T75924
Synonym:
Target:
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
Cat.No: T37487
Synonym:
Target:
Dipropetryn
Cat.No: T20834
Synonym: GS-16068,Cotofor,GS 16068,GS16068,Sancap
Target:
Epetraborole
Cat.No: T71458
Synonym:
Target:
Petasinoside
Cat.No: T124362
Synonym:
Target:
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
Cat.No: T37486
Synonym:
Target:
5-FAM-LPETGG TFA
Cat.No: T83718
Synonym: 5-Carboxyfluorescein-LPETGG
Target:
Isopetasol
Cat.No: T124819
Synonym:
Target:
Nepetaside
Cat.No: T126348
Synonym:
Target:
Petasitenine
Cat.No: T124576
Synonym:
Target:
Gossypetin 3-methylether
Cat.No: T124054
Synonym:
Target:
(±)8(9)-EpETE
Cat.No: T37228
Synonym:
Target:
Competence-Stimulating Peptide-2 (CSP-2)
Cat.No: T38559
Synonym:
Target:
HIV-IN petide
Cat.No: T76603
Synonym:
Target:
PETCM
Cat.No: T12413
Synonym:
Target: Others
(±)5(6)-EpETE methyl ester
Cat.No: T37224
Synonym:
Target:
17R(18S)-EpETE
Cat.No: T36215
Synonym:
Target:
Neopetasitenine
Cat.No: T124565
Synonym:
Target:
5(S)​-​HPETE
Cat.No: T40826
Synonym:
Target:
Nepetalactone
Cat.No: T33643
Synonym: MD(sub 1) 84,MDI 84
Target:
Petiolin G
Cat.No: T126232
Synonym:
Target:
Dilopetine Citrate
Cat.No: T27175
Synonym: E-6006 Citrate,E-6039,E6039,E 6039
Target:
Competence-Stimulating Peptide-12261
Cat.No: TP1631
Synonym:
Target:
APETx2
Cat.No: TP2081
Synonym:
Target:
Petromyzonol
Cat.No: T37798
Synonym:
Target:
12(S)-HpETE
Cat.No: T37969
Synonym:
Target:
Apetalactone
Cat.No: T131502
Synonym:
Target:
15(S)-HpETE
Cat.No: T35943
Synonym:
Target:
Mesdopetam
Cat.No: T38828
Synonym: IRL790
Target:
Cyclopetide 2
Cat.No: T80380
Synonym:
Target:
Competence-Stimulating Peptide-12261 acetate
Cat.No: TP1631L
Synonym: Competence-Stimulating Peptide-12261 acetate (1235882-91-3 free base)
Target: Others
(±)14(15)-EpETE
Cat.No: T37234
Synonym:
Target:
Epetraborole R-Mandelate
Cat.No: T71168
Synonym:
Target:
Petesicatib
Cat.No: T16474
Synonym:
Target: Cysteine Protease
Cat. No. Product Name Target Signaling Pathways
T8287 Edpetiline

Sipeimine-3β-D-glucoside,西贝母碱苷

Others Others
Sipeimine-3β-D-glucoside 是一种来自 P.eduardi 的主要生物碱。它具有显著的抗炎活性。
TN1154 Nepetin

6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素

Calcium Channel; Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
Nepetin (6-Methoxyluteolin) 是一种分离自Eupatorium ballotaefoliumHBK 中的天然类黄酮,具有有效的抗炎作用。它在 ARPE-19 细胞中能够抑制IL-6(IC50:4.43 μM) 、IL-8 (IC50:43.42 μM) 、MCP-1 (IC50:4.17 μM) 的分泌。
T4870 Petroselinic acid

5-Heptadecylene-1-carboxylic acid,十八碳6烯酸

Endogenous Metabolite Metabolism
Petroselinic acid (5-Heptadecylene-1-carboxylic acid) 是一种从芫荽的植物油中得到的油酸异构体。
TN1711 Gossypetin

Antioxidant; p38 MAPK; MAPK; Antibacterial MAPK; Microbiology/Virology; oxidation-reduction
Gossypetin 是一种可从Rhodiola rosea Linn.中提取的六羟基化的类黄酮,是一种有效的 MKK3 和 MKK6 抑制剂,可强烈减弱 MKK3/6-p38 信号传导途径。Gossypetin 具有抗突变、抗动脉粥样硬化、抗氧化以及细胞保护和抗菌作用,它通过下调溶酶体酪蛋白酶 K 的活性和诱导肌动蛋白环破骨细胞中的自噬相关蛋白来抑制骨吸收。
TN3533 Borapetoside F

Others Others
Borapetoside F是一种天然产物,属于防己科青牛胆属,其产品编号为 TN3533,CAS号为 151200-50-9。Borapetoside F可用作对照参考。
TN3531 Borapetoside D

Others Others
Borapetoside D是一种天然产物,属于防己科青牛胆属,其产品编号为 TN3531,CAS号为 151200-48-5。Borapetoside D可用作对照参考。
T81508 Petanin chloride

Petanin (chloride) 为一种香豆素类花青素,源自彩色马铃薯块茎表皮。
T82269 Gossypetin 3-sophoroside-8-glucoside

Gossypetin 3-sophoroside-8-glucoside,一种黄酮醇苷,可分离自木贼(Equisetum hyemale L.)地上部分。
TN3795 Dehydroborapetoside B

Others Others
Dehydroborapetoside B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3795,CAS号为 1221178-16-0。
T72250 4aα,7α,7aα-Nepetalactone

4aα,7α,7aα-Nepetalactone 具有抗菌 (antibacterial) 活性,抑制Escherichia coli,Pseudomonas aeruginosa,Staphylococcus aureus,Salmonella typhi 和Enterococcus faecalis。
TN2059 Petunidin-3-O-galactoside chloride

氯化矮牵牛素半乳糖苷,氯化矮牵牛素-3-O-半乳糖苷

Others Others
Petunidin-3-O-galactoside chloride has antioxidant activity.
TN3255 7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone

Others Others
7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone shows diacylglycerol acyltransferase (DGAT)1 inhibition with IC(50) values of 47.0 microM (for rat liver microsomes) and 160.7 microM (for HepG2 cell microsomes),
TN2061 Petunidin chloride

Others Others
Petunidin chloride has antioxidant, and anti-carcinogenesis activities.
TN1732 Herpetone

HBV Microbiology/Virology
Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity.
TN3530 Borapetoside B

Others Others
Borapetoside B是一种天然产物,属于防己科青牛胆属,其产品编号为 TN3530,CAS号为 104901-05-5。Borapetoside B可用作对照参考。
T72803 Norartocarpetin

Norartocarpetin 是一种酪氨酸酶抑制剂。Norartocarpetin 具有较强的酪氨酸酶抑制活性,其抑制活性 IC50值为 0.47 μM。Norartocarpetin 作为一种抗褐变剂可用于食品体系的研究。Norartocarpetin 对肺癌细胞 (NCI-H460) 也具有显著的抗癌活性,其 IC50值为 22 μM。Norartocarpetin 的抗增殖作用是通过靶向 Ras/Raf/MAPK 信号通路、线粒体介导的细胞凋亡、S 期细胞周期阻滞和抑制细胞迁移和侵袭实现的。
TN4648 Nepetoidin B

IL Receptor; p38 MAPK; TNF; NOS; NF-κB; COX; Antibacterial; JNK; Antifection; Antifungal Apoptosis; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience; NF-κB
Nepetoidin B 具有抗真菌、抗细菌和抗炎作用,它可以抑制 LPS 刺激的 NO 生成,可能是通过调节 RAW 264.7 细胞中由 MKP-5/NF-κB 通路介导的 iNOS 。
T81507 Petunidin 3-rutinoside

Petunidin 3-rutinoside,一种可从Sambucus canadensis分离的天然产物。
TN3532 Borapetoside E

Others Others
Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice.
TN4264 Isoapetalic acid

胡桐,海棠木

HIV Protease; Antifection Microbiology/Virology; Proteases/Proteasome
Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive bacteria, S. aureus and B. subtilis a
T40458 3-Keto petromyzonol

3-Keto petromyzonol, a key constituent of Sea lamprey male sex pheromones, governs the synthesis and release of gonadotropin releasing hormone (GnRH). This in turn regulates the hypothalamic-pituitary-gonadal (HPG) output in immature sea lamprey.
TN6621 Petunidin-3-O-arabinoside chloride

1. Petunidin-3-O-arabinoside chloride has antioxidant activity .
TN2060 Petunidin-3-O-glucoside chloride

Others Others
Petunidin-3-O-glucoside chloride has significantly higher antioxidant activity than the Fe2+ control. Petunidin-3-O-glucoside causes problems in digestibility, may be important dietary supplements with beneficial health effects.
TN5750 Petiolin F

Petiolin F 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5750,CAS号为 1204251-10-4。
T81506 Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside

Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside 是葡萄中可分离提取的天然产物。
T35910 Petromurin C

Petromurin C is a bis-indolyl benzenoid fungal metabolite originally isolated from the ascostromata of P. muricatus. It is cytotoxic to NS-1 mouse myeloma cells (IC50 = 33 μg/ml) and has activity against T. foetus in vitro (IC50 = 100 μg/ml).
T8031 Terephthalic acid

Others; Endogenous Metabolite Metabolism; Others
Terephthalic acid 是一种三种酞酸盐的异构体,是聚酯 PET 的前体,能够用于制作服装和塑料。

天然产物

Edpetiline
Cat.No: T8287
Synonym: Sipeimine-3β-D-glucoside,西贝母碱苷
Target: Others
Nepetin
Cat.No: TN1154
Synonym: 6-Methoxyluteolin,泽兰黄酮,6-甲氧基藤黄菌素
Target: Calcium Channel, Histamine Receptor
Petroselinic acid
Cat.No: T4870
Synonym: 5-Heptadecylene-1-carboxylic acid,十八碳6烯酸
Target: Endogenous Metabolite
Gossypetin
Cat.No: TN1711
Synonym:
Target: Antioxidant, p38 MAPK, MAPK, Antibacterial
Borapetoside F
Cat.No: TN3533
Synonym:
Target: Others
Borapetoside D
Cat.No: TN3531
Synonym:
Target: Others
Petanin chloride
Cat.No: T81508
Synonym:
Target:
Gossypetin 3-sophoroside-8-glucoside
Cat.No: T82269
Synonym:
Target:
Dehydroborapetoside B
Cat.No: TN3795
Synonym:
Target: Others
4aα,7α,7aα-Nepetalactone
Cat.No: T72250
Synonym:
Target:
Petunidin-3-O-galactoside chloride
Cat.No: TN2059
Synonym: 氯化矮牵牛素半乳糖苷,氯化矮牵牛素-3-O-半乳糖苷
Target: Others
7beta-(3-Ethyl-cis-crotonoyloxy)-1alpha-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone
Cat.No: TN3255
Synonym:
Target: Others
Petunidin chloride
Cat.No: TN2061
Synonym:
Target: Others
Herpetone
Cat.No: TN1732
Synonym:
Target: HBV
Borapetoside B
Cat.No: TN3530
Synonym:
Target: Others
Norartocarpetin
Cat.No: T72803
Synonym:
Target:
Nepetoidin B
Cat.No: TN4648
Synonym:
Target: IL Receptor, p38 MAPK, TNF, NOS, NF-κB, COX, Antibacterial, JNK, Antifection, Antifungal
Petunidin 3-rutinoside
Cat.No: T81507
Synonym:
Target:
Borapetoside E
Cat.No: TN3532
Synonym:
Target: Others
Isoapetalic acid
Cat.No: TN4264
Synonym: 胡桐,海棠木
Target: HIV Protease, Antifection
3-Keto petromyzonol
Cat.No: T40458
Synonym:
Target:
Petunidin-3-O-arabinoside chloride
Cat.No: TN6621
Synonym:
Target:
Petunidin-3-O-glucoside chloride
Cat.No: TN2060
Synonym:
Target: Others
Petiolin F
Cat.No: TN5750
Synonym:
Target:
Petunidin-3-O-(6-O-p-coumaryl)-5-O-diglucoside
Cat.No: T81506
Synonym:
Target:
Petromurin C
Cat.No: T35910
Synonym:
Target:
Terephthalic acid
Cat.No: T8031
Synonym:
Target: Others, Endogenous Metabolite
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