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Search Results for " pdgf-c "
Targets Recommended: Apoptosis FGFR FLT PDGFR c-Kit

6

抑制剂 & 化合物

1

天然产物

36

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6711 Tyrphostin AG1296

Tyrphostin AG 1296,AG 1296

Apoptosis; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Tyrphostin AG1296 (Tyrphostin AG 1296) 抑制人PDGF α和β受体以及相关干细胞因子受体的信号传导,是一种选择性血小板衍生生长因子受体抑制剂,IC50值为 0.8 μM。
T0097L Pazopanib

帕唑帕尼,GW786034

VEGFR; FGFR; PDGFR; c-Kit; Autophagy Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
Pazopanib (GW786034) 是一种小分子抑制剂,可抑制多种具有潜在抗肿瘤活性的蛋白酪氨酸激酶。它抑制VEGFR1、VEGFR2、VEGFR3、PDGFRβ、c-Kit、FGFR1和c-Fms 的IC50分别为10、30、47、84、74、140和146 nM。
T4191 Multi-kinase inhibitor 1

Multi-kinase inhibitor I

Others; Bcr-Abl; PDGFR; c-Kit Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) 是多激酶抑制剂。它有用于导致与酪氨酸激酶活性异常或失控有关的疾病或失调的潜力,特别是与c-Kit,PDGF-R,Bcr-abl 活性相关的疾病。
T23127 PD-161570

PD 161570

EGFR; FGFR; PDGFR; Src Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD-161570 是一种有效的 ATP 竞争性人 FGF-1 受体抑制剂,IC50 为 39.9 nM,Ki 为 42 nM。它还是骨形态发生蛋白 (BMPs) 和TGF-β信号抑制剂。它抑制PDGF 刺激的自磷酸化和FGF-1受体磷酸化,IC50分别为 450 和 622 nM。它抑制 PDGFR、EGFR 和 c-Src 酪氨酸激酶,IC50 值分别为 310、240 和 44 nM。
T67442 CGP-53716

The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase inhibition has been shown to be effective in blocking tyrosine phosphorylation at the PDGF and bFGF receptors in cultured fibroblast and vascular smooth muscle cells which in turn inhibits their proliferation[1]. CGP 53716 is a specific PDGFR tyrosine kinase inhibitor on SMC (smoo...
T37079 VEGFR2 Kinase Inhibitor II

Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms A, C, and D. VEGFR2 kinase inhibitor II is a reversible, cell-permeable inhibitor of VEGFR2's kinase activity (IC50 = 70 nM). It less potently inhibits the platelet-derived growth factor receptor β (PDGFRβ; IC50 = 920 nM) and related receptor and non-receptor tyrosine kinases. V...

化合物

Tyrphostin AG1296
Cat.No: T6711
Synonym: Tyrphostin AG 1296,AG 1296
Target: Apoptosis, FGFR, FLT, PDGFR, c-Kit
Pazopanib
Cat.No: T0097L
Synonym: 帕唑帕尼,GW786034
Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Multi-kinase inhibitor 1
Cat.No: T4191
Synonym: Multi-kinase inhibitor I
Target: Others, Bcr-Abl, PDGFR, c-Kit
PD-161570
Cat.No: T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
CGP-53716
Cat.No: T67442
Synonym:
Target:
VEGFR2 Kinase Inhibitor II
Cat.No: T37079
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T5S1103 Isoliensinine

异莲心碱,Isoliensinin

Apoptosis; Antioxidant Apoptosis; oxidation-reduction
Isoliensinine (Isoliensinin) 是从水芙蓉种子胚中提取的一种双苄基异喹啉生物碱,能诱导三阴性乳腺癌细胞凋亡,具有抗氧化、抗炎、抗癌活性。

天然产物

Isoliensinine
Cat.No: T5S1103
Synonym: 异莲心碱,Isoliensinin
Target: Apoptosis, Antioxidant
Cat. No. Product Name Species Expression System
TMPY-04976 PDGFC Protein, Mouse, Recombinant (His)

platelet derived growth factor C,血小板源生长因子,...

Mouse Yeast
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-04644 PDGFB Protein, Human, Recombinant (His)

platelet-derived growth factor beta polypeptide,SSV...

Human Yeast
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
TMPY-02251 PDGFC Protein, Mouse, Recombinant (hFc)

1110064L01Rik,PDGF-C,AI647969,血小板源生长因子,pla...

Mouse HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-01008 VEGFD Protein, Human, Recombinant (His)

VEGFD,c-fos induced growth factor...

Human HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs an...
TMPY-04051 c-Kit Protein, Human, Recombinant (hFc)

SCFR,v-kit Hardy-Zuckerman 4 feline sar

Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-01802 c-Kit Protein, Mouse, Recombinant (His)

SCO5,SCO1,Bs,Gsfsco1,v-kit Hardy-...

Mouse HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-05655 c-Kit Protein, Rhesus, Recombinant (hFc)

v-kit Hardy-Zuckerman 4 feline sarcoma vir...

Rhesus HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-01935 c-Kit Protein, Human, Recombinant (His)

PBT,CD117,v-kit Hardy-Zuckerman 4 feline s...

Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His)

VEGFA,VEGF-A,Vascular permeability factor,...

Human Human Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPK-00420 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated

RHEPDGFRA,PDGFRA,PDGF R α/PDG...

Human HEK293
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF.
TMPK-00943 PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)

PDGF R α/PDGFRA Protein, Cynomolg...

Cynomolgus HEK293
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF.
TMPY-00269 PDGFC Protein, Cynomolgus, Recombinant (hFc)

platelet derived growth factor C,血小板源生长因子

Cynomolgus HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-02815 PDGFC Protein, Human, Recombinant (His)

platelet derived growth factor C,FALLOTEIN...

Human Baculovirus-Insect Cells
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPY-00898 PDGFC Protein, Human, Recombinant (hFc)

血小板源生长因子,FALLOTEIN,SCDGF,platelet derived growth fa...

Human HEK293
PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyrosine kinase activity. They have roles in the regulation of many biological processes including embryonic development, angiogenesis, cell proliferation and differentiation, and contribute to the pathophysiology of some diseases, including cancer. There are two isoforms of the PDG...
TMPK-00419 PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)

RHEPDGFRA,PDGFR-2,CD140A,PDGF...

Human HEK293
Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, PDGF-B chain, PDGF-C chain and PDGF-D chain, which in active forms are dimers. As far as two receptors PDGF-alpha R and PDGF-beta R are known to bind PDGF.
TMPK-00414 M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)

FMSFIM2,FMS,M-CSF R,HDLS,M-CSFR,C...

Human HEK293
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferat...
TMPJ-00402 CD117 Protein, Human, Recombinant (hFc)

KIT,CD117,v-kit Hardy-Zuckerman 4 feline s...

Human Human Cells
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily and CSF-1/PDGF receptor subfamily. SCF R expression on mast cells enables them to infiltrate SCF-secreting tumors where they promote tumor growth and induce local immune suppression. SCF R is up-regulated on dendritic cells by Th2-orTh17-biasing sti...
TMPY-02589 VEGFD Protein, Mouse, Recombinant (hFc)

c-fos induced growth factor (vas<...

Mouse HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs an...
TMPY-03150 VEGFD Protein, Mouse, Recombinant (His)

VEGF-D,Vegfd,AI325264,c-fos induced growth...

Mouse HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs an...
TMPY-03200 VEGFD Protein, Rat, Recombinant (hFc)

c-fos induced growth factor (vas<...

Rat HEK293
Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. FIGF protein is secreted as a non-covelent homodimer in an antiparallel fashion. Human FIGF protein is expressed in adult lung, heart, muscle, and small intestine, and is most abundantly expressed in fetal lungs an...
TMPK-00415 M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated

CSF-1-R,M-CSF R,C-FMS,FMSFIM2,

Human HEK293
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferat...
TMPK-00656 M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)

M-CSF R,M-CSFR,HDLS,C-FMS,C

Cynomolgus HEK293
CSF1R also known as M-CSF receptor, the product of the c-fms proto-oncogene, is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region.CSF1R is tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferat...
TMPJ-00011 CXCL2 Protein, Mouse, Recombinant

Gro-beta,GRO β,GROB,melanoma growth stimulatory act...

Mouse E. coli
C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. The expression of mouse MIP-2 is stimulated by endotoxin. The mouse MIP-2 shares approximately 63% aa sequence identity with murine KC, another mouse alpha chemokine, which is induced by PDGF. It has been suggested that mouse KC and MIP-2 are the homologs of the hum...
TMPY-03567 c-Kit Protein, Human, Recombinant (aa 50-190, His)

SCFR,PBT,C-Kit,CD117,v-kit Hardy-...

Human E. coli
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-06656 c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated

CD117,SCFR,C-Kit,v-kit Hardy-Zu

Human HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-04564 c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)

C-Kit,PBT,SCFR,CD117,v-kit Hardy-...

Human Baculovirus-Insect Cells
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-01801 c-Kit Protein, Mouse, Recombinant (hFc)

SCO1,Gsfsco1,W,v-kit Hardy-Zucker...

Mouse HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-06652 c-Kit Protein, Rhesus, Recombinant (His)

v-kit Hardy-Zuckerman 4 feline sarcoma vir...

Rhesus HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-03136 c-Kit Protein, Rat, Recombinant (His)

v-kit Hardy-Zuckerman 4 feline sarcoma vir...

Rat HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPY-03034 c-Kit Protein, Rat, Recombinant (hFc)

v-kit Hardy-Zuckerman 4 feline sarcoma vir...

Rat HEK293
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the protein kinase superfamily, tyr protein kinase family, and CSF-1/PDGF receptor subfamily. C-Kit has tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase. Antibodies...
TMPJ-01418 CSF1R Protein, Cynomolgus, Recombinant (hFc)

M-CSF-R,CSF1R,CSF-1-R,CS...

Cynomolgus Human Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPY-02763 DEP-1 Protein, Human, Recombinant (aa 997-1337, His)

HPTPeta,SCC1,protein tyrosine phosphatase,...

Human E. coli
DEP1 / PTPRJ (Receptor-type tyrosine-protein phosphatase eta) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. DEP1 / PTPRJ possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-...
TMPJ-01419 CSF1R Protein, Cynomolgus, Recombinant (His)

CSF-1-R,CSF-1 receptor,Proto-on

Cynomolgus Human Cells
Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ...
TMPK-01450 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated

KRAS1,MHC,K-RAS4B,KRAS,CFC2,K-RAS...

Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01451 HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)

NS3,K-RAS4A,K-Ras 2,NS,KRAS1,RASK2,MHC,KI-RAS,KRAS,...

Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
TMPK-01456 HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)

KRAS2,NS,MHC,C-K-RAS,KRAS1,K-RAS2A,K-RAS2B...

Human HEK293
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.

重组蛋白

PDGFC Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04976
Species: Mouse
Expression System: Yeast
PDGFB Protein, Human, Recombinant (His)
Cat.No: TMPY-04644
Species: Human
Expression System: Yeast
PDGFC Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02251
Species: Mouse
Expression System: HEK293
VEGFD Protein, Human, Recombinant (His)
Cat.No: TMPY-01008
Species: Human
Expression System: HEK293
c-Kit Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04051
Species: Human
Expression System: HEK293
c-Kit Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01802
Species: Mouse
Expression System: HEK293
c-Kit Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-05655
Species: Rhesus
Expression System: HEK293
c-Kit Protein, Human, Recombinant (His)
Cat.No: TMPY-01935
Species: Human
Expression System: HEK293
VEGF121 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00865
Species: Human
Expression System: Human Cells
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00420
Species: Human
Expression System: HEK293
PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00943
Species: Cynomolgus
Expression System: HEK293
PDGFC Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-00269
Species: Cynomolgus
Expression System: HEK293
PDGFC Protein, Human, Recombinant (His)
Cat.No: TMPY-02815
Species: Human
Expression System: Baculovirus-Insect Cells
PDGFC Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00898
Species: Human
Expression System: HEK293
PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00419
Species: Human
Expression System: HEK293
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00414
Species: Human
Expression System: HEK293
CD117 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00402
Species: Human
Expression System: Human Cells
VEGFD Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02589
Species: Mouse
Expression System: HEK293
VEGFD Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03150
Species: Mouse
Expression System: HEK293
VEGFD Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03200
Species: Rat
Expression System: HEK293
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00415
Species: Human
Expression System: HEK293
M-CSFR/CSF1R/CD115 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00656
Species: Cynomolgus
Expression System: HEK293
CXCL2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00011
Species: Mouse
Expression System: E. coli
c-Kit Protein, Human, Recombinant (aa 50-190, His)
Cat.No: TMPY-03567
Species: Human
Expression System: E. coli
c-Kit Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06656
Species: Human
Expression System: HEK293
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST)
Cat.No: TMPY-04564
Species: Human
Expression System: Baculovirus-Insect Cells
c-Kit Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01801
Species: Mouse
Expression System: HEK293
c-Kit Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-06652
Species: Rhesus
Expression System: HEK293
c-Kit Protein, Rat, Recombinant (His)
Cat.No: TMPY-03136
Species: Rat
Expression System: HEK293
c-Kit Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03034
Species: Rat
Expression System: HEK293
CSF1R Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01418
Species: Cynomolgus
Expression System: Human Cells
DEP-1 Protein, Human, Recombinant (aa 997-1337, His)
Cat.No: TMPY-02763
Species: Human
Expression System: E. coli
CSF1R Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-01419
Species: Cynomolgus
Expression System: Human Cells
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01450
Species: Human
Expression System: HEK293
HLA-C 03:04&B2M&KRAS G12D (GADGVGKSAL) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01451
Species: Human
Expression System: HEK293
HLA-C*03:04&B2M&KRAS G12D (GADGVGKSAL) Tetramer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01456
Species: Human
Expression System: HEK293
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