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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6592 |
ML133 hydrochloride
ML133 HCl,(4-甲氧基苄基)(1-萘基甲基)胺盐酸盐 |
Potassium Channel | Membrane transporter/Ion channel |
ML133 hydrochloride (ML133 HCl) 是选择性的Kir2家族通道抑制剂,在pH 7.4 和pH 8.5 时的IC50值分别为1.8 μM 和290 nM。 | |||
T8970 |
ML162
|
Ferroptosis; GPX; Glutathione Peroxidase | Apoptosis; Metabolism; oxidation-reduction |
ML162 是一种共价谷胱甘肽过氧化物酶 4 抑制剂。它选择性抑制表达突变 RAS 癌基因的细胞系。 | |||
T8986 |
ML198
|
Glucokinase | Metabolism |
ML198 是葡萄糖脑苷脂酶激活剂(EC50:0.4 μM)。它不会抑制该酶的作用,且能促进其易位至溶酶体,可用于研究戈谢病。 | |||
T2463 |
ML141
CID-2950007 |
Apoptosis; CDK; Ras | Apoptosis; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK |
ML141 (CID-2950007) 是一种高效变构,选择性可逆的 Cdc42 GTPase 非竞争性抑制剂,IC50值为200 nM。它抑制 Cdc42 野生型和 Cdc42 Q61L 突变体。 | |||
T35544 |
ML115
|
STAT | JAK/STAT signaling; Stem Cells |
ML115 是一种有效且选择性的转录 3 (STAT3) 激活剂,abn EC50 为 2.0 nM,对相关的 STAT1 和 NFκB 抗靶点无活性。 | |||
T8514 |
LML134
LML-134 |
Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
LML134 (LML-134) 是一种可口服的高选择性组胺 H3 受体反向激动剂,有用于过度睡眠障碍的潜力,对 hH3R 的 cAMP 和 bdg 的Kis 分别为 0.3 和 12 nM。 | |||
T8597 |
ML116
|
STAT | JAK/STAT signaling; Stem Cells |
ML116 是一种有效的选择性 STAT3 抑制剂。 | |||
T8954 |
ML179
ML-179 |
Others | Others |
ML179 是一种有效的选择性肝受体同源物 1 (LRH1, NR5A2) 反向激动剂,IC50 为 320 nM。 | |||
T8371 |
ML188
|
Virus Protease; SARS-CoV | Microbiology/Virology |
ML188是一种选择性非共价 SARS-CoV3CLpro 抑制剂,具有抗病毒活性,IC50为 1.5 μM。 | |||
T33452 |
ML192
ML-192,CID1434953,CID 1434953,ML 192,CID-1434953 |
Cannabinoid Receptor; GPR; Arrestin | Endocrinology/Hormones; GPCR/G Protein |
ML192 (CID1434953) 是一种具有选择性的 GPR55 配体拮抗剂。ML192 是一种抑制剂,可抑制 β-arrestin 转运、ERK1/2 磷酸化和 PKCβII 易位。 | |||
T2670 |
ML167
NCGC00188654,CID44968231 |
DYRK; CDK | Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
ML167 (CID44968231) 是一种高选择性的 Cdc2 样激酶 4 抑制剂,IC50为 136 nM。 | |||
T28063 |
ML169
ML 169,ML-169 |
||
ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM). | |||
T64738 | 16-(S)-ML188 | ||
16-(S)-ML188 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64738。 | |||
T16105 |
ML132
NCGC 00185682 |
Others | Others |
ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM). | |||
T62168 |
ML138
|
||
ML138 是一种 MLPCN 的探针,是一种 κ opioid 受体的激动剂。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03802 |
IL-17F Protein, Human, Recombinant (aa 31-163)
ML1,ML-1,IL-17F... |
Human | E. coli |
IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1. | |||
TMPY-01898 |
IL-17F Protein, Human, Recombinant (aa 31-163, His)
CANDF6,IL-17F,interleukin 17F,ML-... |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (aa 31-163, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q96PD4. | |||
TMPY-05461 |
IL-17F Protein, Human, Recombinant (His), Biotinylated
ML-1,CANDF6,interleukin 17F,IL- |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.3 kDa and the accession number is Q96PD4. | |||
TMPK-00042 |
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
CANDF6,ML1,Cytokine ML-1... |
Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1. | |||
TMPK-00046 |
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
CANDF6,IL-24,IL24,IL17F,Cytokine ML-1<... |
Human | HEK293 Cells |
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /14.9 kDa and the accession number is Q96PD4. | |||
TMPK-00041 |
IL-17F Protein, Mouse, Recombinant (His & Avi)
IL-24,IL17F,ML1,IL-17F,C... |
Mouse | HEK293 Cells |
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1. | |||
TMPK-00620 |
TLT-1/TREML1 Protein, Mouse, Recombinant (hFc)
UNQ1825/PRO3438,TLT1,Trem-like transcript ... |
Mouse | HEK293 Cells |
Triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (TLT-1) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-baring TREM family protein. Triggering receptor expressed on myeloid cells (TREM) like transcript-1 (TLT-1) is a membrane protein receptor found in alpha-granules of platelets and megakaryocytes. | |||
TMPJ-00193 |
TREML1 Protein, Human, Recombinant (hFc)
TLT-1,Trem-Like Transcript 1 Protein,TLT |
Human | HEK293 Cells |
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic... | |||
TMPY-01840 |
TLT-1/TREML1 Protein, Human, Recombinant (His)
PRO3438,TLT-1,triggering receptor expressed on myel... |
Human | HEK293 Cells |
Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusively in platelets and megakaryocytes (MKs) and that its expression is up-regulated dramatically upon platelet activation. It is a receptor that may play a role in the innate and adaptive immune response. TREML1 / TLT-1 contains the characteristic single V-set immunoglobulin (Ig) do... |