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Search Results for " ml1 "
Targets Recommended: Potassium Channel

15

抑制剂 & 化合物

9

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T6592 ML133 hydrochloride

ML133 HCl,(4-甲氧基苄基)(1-萘基甲基)胺盐酸盐

Potassium Channel Membrane transporter/Ion channel
ML133 hydrochloride (ML133 HCl) 是选择性的Kir2家族通道抑制剂,在pH 7.4 和pH 8.5 时的IC50值分别为1.8 μM 和290 nM。
T8970 ML162

Ferroptosis; GPX; Glutathione Peroxidase Apoptosis; Metabolism; oxidation-reduction
ML162 是一种共价谷胱甘肽过氧化物酶 4 抑制剂。它选择性抑制表达突变 RAS 癌基因的细胞系。
T8986 ML198

Glucokinase Metabolism
ML198 是葡萄糖脑苷脂酶激活剂(EC50:0.4 μM)。它不会抑制该酶的作用,且能促进其易位至溶酶体,可用于研究戈谢病。
T2463 ML141

CID-2950007

Apoptosis; CDK; Ras Apoptosis; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
ML141 (CID-2950007) 是一种高效变构,选择性可逆的 Cdc42 GTPase 非竞争性抑制剂,IC50值为200 nM。它抑制 Cdc42 野生型和 Cdc42 Q61L 突变体。
T35544 ML115

STAT JAK/STAT signaling; Stem Cells
ML115 是一种有效且选择性的转录 3 (STAT3) 激活剂,abn EC50 为 2.0 nM,对相关的 STAT1 和 NFκB 抗靶点无活性。
T8514 LML134

LML-134

Histamine Receptor GPCR/G Protein; Immunology/Inflammation; Neuroscience
LML134 (LML-134) 是一种可口服的高选择性组胺 H3 受体反向激动剂,有用于过度睡眠障碍的潜力,对 hH3R 的 cAMP 和 bdg 的Kis 分别为 0.3 和 12 nM。
T8597 ML116

STAT JAK/STAT signaling; Stem Cells
ML116 是一种有效的选择性 STAT3 抑制剂。
T8954 ML179

ML-179

Others Others
ML179 是一种有效的选择性肝受体同源物 1 (LRH1, NR5A2) 反向激动剂,IC50 为 320 nM。
T8371 ML188

Virus Protease; SARS-CoV Microbiology/Virology
ML188是一种选择性非共价 SARS-CoV3CLpro 抑制剂,具有抗病毒活性,IC50为 1.5 μM。
T33452 ML192

ML-192,CID1434953,CID 1434953,ML 192,CID-1434953

Cannabinoid Receptor; GPR; Arrestin Endocrinology/Hormones; GPCR/G Protein
ML192 (CID1434953) 是一种具有选择性的 GPR55 配体拮抗剂。ML192 是一种抑制剂,可抑制 β-arrestin 转运、ERK1/2 磷酸化和 PKCβII 易位。
T2670 ML167

NCGC00188654,CID44968231

DYRK; CDK Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
ML167 (CID44968231) 是一种高选择性的 Cdc2 样激酶 4 抑制剂,IC50为 136 nM。
T28063 ML169

ML 169,ML-169

ML169 is a selective and brain penetrant M1 positive allosteric modulator (PAM).
T64738 16-(S)-ML188

16-(S)-ML188 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64738。
T16105 ML132

NCGC 00185682

Others Others
ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).
T62168 ML138

ML138 是一种 MLPCN 的探针,是一种 κ opioid 受体的激动剂。

化合物

ML133 hydrochloride
Cat.No: T6592
Synonym: ML133 HCl,(4-甲氧基苄基)(1-萘基甲基)胺盐酸盐
Target: Potassium Channel
ML162
Cat.No: T8970
Synonym:
Target: Ferroptosis, GPX, Glutathione Peroxidase
ML198
Cat.No: T8986
Synonym:
Target: Glucokinase
ML141
Cat.No: T2463
Synonym: CID-2950007
Target: Apoptosis, CDK, Ras
ML115
Cat.No: T35544
Synonym:
Target: STAT
LML134
Cat.No: T8514
Synonym: LML-134
Target: Histamine Receptor
ML116
Cat.No: T8597
Synonym:
Target: STAT
ML179
Cat.No: T8954
Synonym: ML-179
Target: Others
ML188
Cat.No: T8371
Synonym:
Target: Virus Protease, SARS-CoV
ML192
Cat.No: T33452
Synonym: ML-192,CID1434953,CID 1434953,ML 192,CID-1434953
Target: Cannabinoid Receptor, GPR, Arrestin
ML167
Cat.No: T2670
Synonym: NCGC00188654,CID44968231
Target: DYRK, CDK
ML169
Cat.No: T28063
Synonym: ML 169,ML-169
Target:
16-(S)-ML188
Cat.No: T64738
Synonym:
Target:
ML132
Cat.No: T16105
Synonym: NCGC 00185682
Target: Others
ML138
Cat.No: T62168
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03802 IL-17F Protein, Human, Recombinant (aa 31-163)

ML1,ML-1,IL-17F...

Human E. coli
IL-17F Protein, Human, Recombinant (aa 31-163) is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is AAH70124.1.
TMPY-01898 IL-17F Protein, Human, Recombinant (aa 31-163, His)

CANDF6,IL-17F,interleukin 17F,ML-...

Human HEK293 Cells
IL-17F Protein, Human, Recombinant (aa 31-163, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.2 kDa and the accession number is Q96PD4.
TMPY-05461 IL-17F Protein, Human, Recombinant (His), Biotinylated

ML-1,CANDF6,interleukin 17F,IL-

Human HEK293 Cells
IL-17F Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.3 kDa and the accession number is Q96PD4.
TMPK-00042 IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated

CANDF6,ML1,Cytokine ML-1...

Mouse HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1.
TMPK-00046 IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated

CANDF6,IL-24,IL24,IL17F,Cytokine ML-1<...

Human HEK293 Cells
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.5 /14.9 kDa and the accession number is Q96PD4.
TMPK-00041 IL-17F Protein, Mouse, Recombinant (His & Avi)

IL-24,IL17F,ML1,IL-17F,C...

Mouse HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 17.8 kDa and the accession number is Q7TNI7-1.
TMPK-00620 TLT-1/TREML1 Protein, Mouse, Recombinant (hFc)

UNQ1825/PRO3438,TLT1,Trem-like transcript ...

Mouse HEK293 Cells
Triggering receptor expressed on myeloid cells (TREM)-like transcript-1 (TLT-1) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-baring TREM family protein. Triggering receptor expressed on myeloid cells (TREM) like transcript-1 (TLT-1) is a membrane protein receptor found in alpha-granules of platelets and megakaryocytes.
TMPJ-00193 TREML1 Protein, Human, Recombinant (hFc)

TLT-1,Trem-Like Transcript 1 Protein,TLT

Human HEK293 Cells
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-like V-type (immunoglobulin-like) domain, and 128 amino acid cytoplasmic domain. It can be expressed exclusively in platelets and megakaryocytes (MKs). It is a cell surface receptor that may play a role in the innate and adaptive immune response. TREML1 Sequestered in cytoplasmic...
TMPY-01840 TLT-1/TREML1 Protein, Human, Recombinant (His)

PRO3438,TLT-1,triggering receptor expressed on myel...

Human HEK293 Cells
Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusively in platelets and megakaryocytes (MKs) and that its expression is up-regulated dramatically upon platelet activation. It is a receptor that may play a role in the innate and adaptive immune response. TREML1 / TLT-1 contains the characteristic single V-set immunoglobulin (Ig) do...

重组蛋白

IL-17F Protein, Human, Recombinant (aa 31-163)
Cat.No: TMPY-03802
Species: Human
Expression System: E. coli
IL-17F Protein, Human, Recombinant (aa 31-163, His)
Cat.No: TMPY-01898
Species: Human
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05461
Species: Human
Expression System: HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00042
Species: Mouse
Expression System: HEK293 Cells
IL-17F Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00046
Species: Human
Expression System: HEK293 Cells
IL-17F Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-00041
Species: Mouse
Expression System: HEK293 Cells
TLT-1/TREML1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00620
Species: Mouse
Expression System: HEK293 Cells
TREML1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00193
Species: Human
Expression System: HEK293 Cells
TLT-1/TREML1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01840
Species: Human
Expression System: HEK293 Cells
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