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106

抑制剂 & 化合物

17

天然产物

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Cat. No. Product Name Target Signaling Pathways
T21481 Bromophenol Blue

Others Others
Bromophenol blue 是酸性酞菁染料,可用作电泳的示踪染料。它也是一种 pH 指示剂,pH 指示范围是 3 到 4.6 之间。
T0347 Phenol Red

Sulfonphthal,Sulphental,酚红,Fenolipuna

Others Others
Phenol Red (Sulfonphthal) 是一种pH 指示染料,当出现阳性反应时,会发生由粉红色到黄色的明显颜色变化。
T9344 3-Amino-2-oxazolidinone

Others; Endogenous Metabolite Metabolism; Others
3-Amino-2-oxazolidinone 是一种呋喃唑烷酮的代谢物 (metabolite),可用作检测呋喃唑烷酮残留的一个指标。
T16689 Pyranine

溶剂绿7,HPTS,Solvent Green 7

Others Others
Pyranine (Solvent Green 7) 是一类用于 Cu+离子的荧光化学传感器 (λex=450 nm,λem=510 nm),是 pH 敏感的荧光指示剂。
T7467 Acid orange 7

酸性橙 7,Orange II,D&,C Orange 4,COLIPA C015,2-naphthol orange,CI 15510

Others Others
Acid orange 7 (COLIPA C015) 是一种偶氮染料,是一种指示污染物。它大多存在于在纺织,食品和化妆品工业产生的制造废水中。
TD0103 Safranin

碱性红 2,Safranine T,Basic Red 2

Others Others
Safranin (Basic Red 2) 是一种经典的吩嗪染料,具有平面结构和阳离子电荷,能够轻易插入包括 DNA、蛋白质在内的生物大分子。它在学术领域被广泛用作光谱探针及指示剂,可作为金属离子浓度测定中的氧化还原指示剂。
T9241 o-Cresolphthalein Complexone

Others Others
o-Cresolphthalein Complexone 是一种金属络合指示剂和酸碱指示剂。
T19905 Calcon

NSC-47714,Magracrom Blue,Eriochrome Blue Black R,Mordant Black 17,NSC 47714,Diacromo Blue B,NSC47714

Others Others
Calcon (Mordant Black 17) 是一种钙生化指示剂。
T24170 Iodoantipyrine

碘安替比林,Jodantipyrine,EINECS 204-966-6,Arthripur,Iodophenazone

Others Others
Iodoantipyrine (Arthripur) 是一种常用的指示剂,用于在正常和高CBF 条件下通过测量全身注射指示剂后的循环静脉流出量来评价大鼠。
T14017 2-NBDG

2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖

Others Others
2-NBDG 是一种荧光指示剂 (λex=467 nm,λem=542 nm),是一种荧光 D-葡萄糖类似物,可用于监测活细胞中的葡萄糖吸收。
T20549 Neutral red

Others Others
Neutral Red 是含氮 pH 指示剂(pKi=6.8),是类囊体内部酸化的指示剂。它能够将溶酶体染成红色。
T14855 Calcein

Fluorexon,钙黄绿素

Others Others
Calcein (Fluorexon) 是一种荧光染料和自灭探针,是一种脂囊泡渗漏的指示剂,也是一种 EDTA 钙离子滴定和荧光测定钙离子的络合指示剂。
T2021 Dihydroethidium

二氢乙锭,PD-MY 003,Hydroethidine

Others Others
Dihydroethidium (PD-MY 003) 是一种过氧化物指示剂,在细胞质中具有蓝色荧光,被氧化后荧光消失,λex=518 nm,λem=616 nm。
T0017 Phenolphthalein

Euchessina,Phthalimetten,酚酞,Phthalin

Others Others
Phenolphthalein (Phthalin) 是一种广泛应用的指示剂染料,具有毒性。
T18934 Calmagite

Others Others
Calmagite 是络合指示剂,可用于多种样品中的钙和镁的检测。
T12406 PEPA

iGluR Membrane transporter/Ion channel; Neuroscience
PEPA 是一种变构 AMPA 受体调节剂,可与 GluA2o 和 GluA3o LBD 结合,可用作 AMPA 受体异质性的指标。
T1392 Fluorescein

Solvent Yellow 94,Resorcinol phthalein,荧光素,Yellow fluorescein

Others Others
Fluorescein (Solvent Yellow 94) 是一种合成的有机光敏染料化合物,是一种荧光示踪剂,可以用于医学和生物学以及肿瘤感染的组织。
T75342 MitoSOX Red

Reactive Oxygen Species; Mitochondrial Metabolism; Autophagy Autophagy; Immunology/Inflammation; Metabolism; NF-κB
MitoSOX Red 是一种具有特异性和细胞膜渗透性且靶向活细胞线粒体的新型荧光探针。MitoSOX Red 进入线粒体后会被超氧化物氧化,而不会被其他 ROS 或 RNS 生成系统氧化。MitoSOX Red 随后与线粒体内核酸结合,产生强红色荧光。MitoSOX Red 可以作为荧光指示剂,特异性检测超氧化物。超氧化物歧化酶 (Superoxide dismutase,SOD) 能够预防 MitoSOX Red 氧化。
T20204 Edotreotide

依多曲肽,SMT 487,SMT487,SMT-487

Others Others
Edotreotide (SMT-487) 是生长抑素类似物。它与多种放射性核素联合使用,拥有研究和诊断某些类型癌症的潜能。
T7650 Resazurin sodium

Resazurin sodium salt,刃天青钠,Diazoresorcinol (sodium)

Antibacterial Microbiology/Virology
Resazurin sodium (Resazurin sodium salt) salt 是一种蓝色非荧光染料,广泛用作活细胞的代谢指示剂,通过被还原成荧光产物试卤灵,测量细菌和真核细胞活力。
T3592 MQAE

Others Others
MQAE 是荧光氯离子指示剂,相较于36Cl 同位素示踪法和微电极法,它更加灵敏,更有选择性。
T22229 Acid Yellow 36

Metanil Yellow,酸性黄36

Others Others
Acid Yellow 36 (Metanil Yellow) 是一种偶氮染料和 pH 指示剂,当 pH 值从 1.2 到 2.3 时,发生由红色到黄色的颜色转变。它是 P-450 特异性同工酶和胞浆酶的双功能诱导剂,可用于皮革、造纸和纺织工业。
T4065 Fluorescein Sodium

荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001

Others Others
Fluorescein Sodium (VST-1001) 是一种具有代表性的绿色荧光示踪剂,广泛用于医学、生物应用和肿瘤感染组织的示踪剂,也可作为实用绿色荧光探针的支架。
T0289 9-Aminoacridine

Aminacrine,9-氨基吖啶

Others; HIV Protease; Antibacterial Microbiology/Virology; Others; Proteases/Proteasome
9-Aminoacridine 是一种具有龋齿传播特性的抗菌剂,可用作局部消毒剂。它也是一种高度荧光染料,实验用作一种诱变剂,是细胞内 pH 的指示剂。
T0006 Methylene Blue trihydrate

碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue

Guanylate cyclase; Microtubule Associated; NO Synthase; Parasite; Monoamine Oxidase Cytoskeletal Signaling; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
Methylene Blue trihydrate (Basic blue 9) 是鸟苷酸环化酶,单胺氧化酶 A 和 NO 合酶抑制剂。它是血管加压药,在医疗中通常用作染料。它具有抗伤害感受,抗疟疾,抗抑郁和抗焦虑作用,可用于高铁血红蛋白血症,神经退行性疾病和异环磷酰胺引起的脑病的研究。
T19996 C.I. 37550

Acna Naphthol SS,C.I. Azoic Coupling Component 12,Azoground ITR,Amanil Naphthol AS-ITR,Azotol O,Daito Grounder ITR

C.I. 37550 is an indicator of fluorescent.
T19995 C.I. Azoic Coupling Component 5

NSC 37212,NSC37212,Cibanaphthol AG,Diacetylacetotolidide,Daito Grounder G,NSC-37212

C.I. Azoic Coupling Component 5 is an indicator of fluorescent.
T19901 Eriochrome Black T

NSC7223,NSC-7223,NSC 7223

Eriochrome Black T is a complexometric indicator. Eriochrome Black T is used in complexometric titrations.
T0289L Aminacrine hydrochloride

Aminoacridine hydrochloride,NSC 7571,NSC-7571,Aminacrine HCl,NSC7571

Aminacrine hydrochloride is a highly fluorescent anti-infective dye. It is also used as an intracellular pH indicator.
T38437 NMTCA

N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline

NMTCA (NMTPRO) is a sulfur-containing N-nitrosamino acid utilized as an endogenous nitrosation indicator in gas chromatography-thermal energy analysis.
T29618 Acridine ethidium heterodimer

EINECS 273-155-7

Acridine ethidium heterodimer is a fluorescent indicator.
T30991 CM-H2DCFDA

CMH2DCFDA,CM H2DCFDA

CM-H2DCFDA is a fluorescent indicator for reactive oxygen species (ROS) in cells.
T21280 Aminacrine hydrochloride monohydrate

Aminacrine HCl monohydrate

Aminacrine hydrochloride monohydrate, a highly fluorescent anti-infective dye, is used as a topical antiseptic and mutagen due to its interaction with DNA. It is also used as an intracellular pH indicator.
T23078 NPE-caged-HPTS

Others Others
Caged fluorescent pH indicator
T18995 Fura-2 AM

Fura-2 Acetoxymethyl ester

Others Others
Fura-2 AM is an indicator of ratiometric fluorescent Ca2+.
T29620 Acridine, hydrochloride

monohydrochloride,Acridine,Acridinium chloride

Acridine hydrochloride is a fluorescent indicator.
T19975 C.I. Disperse Red 15

Disperse Red 25,NSC1485,NSC 1485,NSC-1485,Celutate Pink BN

C.I. Disperse Red 15 is a red dye. C.I. Disperse Red 15 is used as a fluorescent indicator.
T20002 Acridine red

CI 45000,C.I. 45000,3B Acridine red hydrochloride

Acridine red is an indicator of fluorescent.
TD0096 5-(and-6)-Carboxy SNARF-1

5-(6)-Carboxy RhodFluor is a cell-impermeant pH indicator.
T7650L Resazurin

Resazoin,Diazoresorcinol,Azoresorcin,Resazurine

Resazurin is used as an oxidation-reduction indicator in cell viability.
T34199 Pyrenelecithin

PPDPC,Pyrene-PC,P10PC

Pyrenelecithin is a fluorescent dye used a lipid indicator.
T37320 Rhod-FF AM

Rhod-FF AM is a cell-permeant acetoxymethyl ester of the fluorescent calcium indicator rhod-FF . As rhod-FF AM enters cells, it is hydrolyzed by intracellular esterases to produce rhod-FF. Rhod-FF is a difluorinated analog of the cell-impermeant calcium indicator rhod-2. It has a very low affinity for calcium (Kd = 320 μM). Low affinity calcium indicators are particularly useful for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes...
T31696 EthD-1

EthD1,Ethidium Homodimer-1

EthD-1 is a cell-impermeant viability indicator. It acts as a high-affinity nucleic acid stain.
T39362 OG 488, acid

OG 488, a fluorescent pH indicator (acid), is widely used in biochemistry and neurosciences, offering numerous applications.
T82736 Chlorophenol Red sodium

Chlorophenol Red sodium作为pH指示剂,在特定pH值范围内通过颜色变化显示酸碱度。
T19046 Phenol Red sodium salt

Phenolsulfonephthalein sodium salt

Others Others
Phenol Red sodium salt is a water-soluble pH indicator used in the range from 6.8 (yellow) to 8.2 (red).
T18921 BCECF-AM

Others Others
BCECF-AM, a compound permeable to cell membranes, serves as a fluorescent indicator for monitoring intracellular pH levels.
T20201 Methyl Orange

NSC9416,NSC-9416,NSC 9416

Methyl orange is a pH indicator frequently. It is used in titration because of its clear and distinct colour variance at different pH values.
T39402 OG 488, SE

Oregon green 488 succinimidyl ester

Oregon Green 488 succinimidyl ester (OG 488, SE), a fluorescent pH indicator, finds extensive applications in the fields of biochemistry and neuroscience.
T71881 Bromophenol red

Bromophenol red (BPR) is a chemical indicator. It has been shown to bind to lysozymes and inhibits their activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan.

化合物

Bromophenol Blue
Cat.No: T21481
Synonym:
Target: Others
Phenol Red
Cat.No: T0347
Synonym: Sulfonphthal,Sulphental,酚红,Fenolipuna
Target: Others
3-Amino-2-oxazolidinone
Cat.No: T9344
Synonym:
Target: Others, Endogenous Metabolite
Pyranine
Cat.No: T16689
Synonym: 溶剂绿7,HPTS,Solvent Green 7
Target: Others
Acid orange 7
Cat.No: T7467
Synonym: 酸性橙 7,Orange II,D&,C Orange 4,COLIPA C015,2-naphthol orange,CI 15510
Target: Others
Safranin
Cat.No: TD0103
Synonym: 碱性红 2,Safranine T,Basic Red 2
Target: Others
o-Cresolphthalein Complexone
Cat.No: T9241
Synonym:
Target: Others
Calcon
Cat.No: T19905
Synonym: NSC-47714,Magracrom Blue,Eriochrome Blue Black R,Mordant Black 17,NSC 47714,Diacromo Blue B,NSC47714
Target: Others
Iodoantipyrine
Cat.No: T24170
Synonym: 碘安替比林,Jodantipyrine,EINECS 204-966-6,Arthripur,Iodophenazone
Target: Others
2-NBDG
Cat.No: T14017
Synonym: 2-(N-7-硝基-2,1,3-苯并恶二唑-4-氨基)-2-脱氧-D-葡萄糖
Target: Others
Neutral red
Cat.No: T20549
Synonym:
Target: Others
Calcein
Cat.No: T14855
Synonym: Fluorexon,钙黄绿素
Target: Others
Dihydroethidium
Cat.No: T2021
Synonym: 二氢乙锭,PD-MY 003,Hydroethidine
Target: Others
Phenolphthalein
Cat.No: T0017
Synonym: Euchessina,Phthalimetten,酚酞,Phthalin
Target: Others
Calmagite
Cat.No: T18934
Synonym:
Target: Others
PEPA
Cat.No: T12406
Synonym:
Target: iGluR
Fluorescein
Cat.No: T1392
Synonym: Solvent Yellow 94,Resorcinol phthalein,荧光素,Yellow fluorescein
Target: Others
MitoSOX Red
Cat.No: T75342
Synonym:
Target: Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy
Edotreotide
Cat.No: T20204
Synonym: 依多曲肽,SMT 487,SMT487,SMT-487
Target: Others
Resazurin sodium
Cat.No: T7650
Synonym: Resazurin sodium salt,刃天青钠,Diazoresorcinol (sodium)
Target: Antibacterial
MQAE
Cat.No: T3592
Synonym:
Target: Others
Acid Yellow 36
Cat.No: T22229
Synonym: Metanil Yellow,酸性黄36
Target: Others
Fluorescein Sodium
Cat.No: T4065
Synonym: 荧光素钠,Fluorescite,VST-1001,Acid yellow 73,VST1001,VST 1001
Target: Others
9-Aminoacridine
Cat.No: T0289
Synonym: Aminacrine,9-氨基吖啶
Target: Others, HIV Protease, Antibacterial
Methylene Blue trihydrate
Cat.No: T0006
Synonym: 碱性亚甲蓝三水合物,Methylthionine chloride,Basic blue 9,亚甲蓝三水合物,Methylene Blue
Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase
C.I. 37550
Cat.No: T19996
Synonym: Acna Naphthol SS,C.I. Azoic Coupling Component 12,Azoground ITR,Amanil Naphthol AS-ITR,Azotol O,Daito Grounder ITR
Target:
C.I. Azoic Coupling Component 5
Cat.No: T19995
Synonym: NSC 37212,NSC37212,Cibanaphthol AG,Diacetylacetotolidide,Daito Grounder G,NSC-37212
Target:
Eriochrome Black T
Cat.No: T19901
Synonym: NSC7223,NSC-7223,NSC 7223
Target:
Aminacrine hydrochloride
Cat.No: T0289L
Synonym: Aminoacridine hydrochloride,NSC 7571,NSC-7571,Aminacrine HCl,NSC7571
Target:
NMTCA
Cat.No: T38437
Synonym: N-Nitroso-2-methylthiazolidine4-carboxylicacid,NMTPRO,N-nitrosomethylthioproline
Target:
Acridine ethidium heterodimer
Cat.No: T29618
Synonym: EINECS 273-155-7
Target:
CM-H2DCFDA
Cat.No: T30991
Synonym: CMH2DCFDA,CM H2DCFDA
Target:
Aminacrine hydrochloride monohydrate
Cat.No: T21280
Synonym: Aminacrine HCl monohydrate
Target:
NPE-caged-HPTS
Cat.No: T23078
Synonym:
Target: Others
Fura-2 AM
Cat.No: T18995
Synonym: Fura-2 Acetoxymethyl ester
Target: Others
Acridine, hydrochloride
Cat.No: T29620
Synonym: monohydrochloride,Acridine,Acridinium chloride
Target:
C.I. Disperse Red 15
Cat.No: T19975
Synonym: Disperse Red 25,NSC1485,NSC 1485,NSC-1485,Celutate Pink BN
Target:
Acridine red
Cat.No: T20002
Synonym: CI 45000,C.I. 45000,3B Acridine red hydrochloride
Target:
5-(and-6)-Carboxy SNARF-1
Cat.No: TD0096
Synonym:
Target:
Resazurin
Cat.No: T7650L
Synonym: Resazoin,Diazoresorcinol,Azoresorcin,Resazurine
Target:
Pyrenelecithin
Cat.No: T34199
Synonym: PPDPC,Pyrene-PC,P10PC
Target:
Rhod-FF AM
Cat.No: T37320
Synonym:
Target:
EthD-1
Cat.No: T31696
Synonym: EthD1,Ethidium Homodimer-1
Target:
OG 488, acid
Cat.No: T39362
Synonym:
Target:
Chlorophenol Red sodium
Cat.No: T82736
Synonym:
Target:
Phenol Red sodium salt
Cat.No: T19046
Synonym: Phenolsulfonephthalein sodium salt
Target: Others
BCECF-AM
Cat.No: T18921
Synonym:
Target: Others
Methyl Orange
Cat.No: T20201
Synonym: NSC9416,NSC-9416,NSC 9416
Target:
OG 488, SE
Cat.No: T39402
Synonym: Oregon green 488 succinimidyl ester
Target:
Bromophenol red
Cat.No: T71881
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3748 orcinol

5-Methylresorcinol,苔黑素、苔黑酚、地衣酚,3,5-Dihydroxytoluene,3,5-二羟基甲苯,地衣酚,5-Methylresorcin,3,5-ToluenediolOrcin,5-Methyl-1,3-benzenediol,Orcin

Others Others
orcinol (5-Methylresorcin) 可用于生物染料和蛋白质组学研究。
T4845 L-Lactic acid

2-HYDROXYPROPIONIC ACID,L-乳酸,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid

Endogenous Metabolite; Antibacterial; Antibiotic Metabolism; Microbiology/Virology
L-Lactic acid ((S)-2-Hydroxypropanoic acid) 属于天然产物,由丙酮酸的无氧糖酵解产生。L-Lactic acid 是组织缺氧的敏感指标,可作为危重病人的血流动力学指标。
T18930 Bromothymol Blue

Others Others
Bromothymol Blue 是 pH 指示剂,在测定弱酸弱碱时使用,在酸性条件下为黄色,在碱性条件下为蓝色。
T14840 Butyrylcarnitine

Endogenous Metabolite Metabolism
Butyrylcarnitine 是血浆中的代谢物,是疾病引起异常代谢的指标,可用于诊断心力衰竭和胰腺囊肿。
T12295 Oleoylcarnitine

Oleoyl-L-carnitine

Endogenous Metabolite Metabolism
Oleoylcarnitine (Oleoyl-L-carnitine) 抑制腺嘌呤核苷酸转位酶 (AdNT) 活性,ic50为14 μM。Oleoylcarnitine 是检测神经分裂的重要指标。
T0613 3-Hydroxyisovaleric acid

β-羟基异戊酸,Beta-Hydroxyisovaleric acid

Others; Endogenous Metabolite Metabolism; Others
3-Hydroxyisovaleric acid (Beta-Hydroxyisovaleric acid) 是尿液中排泄的内源性代谢产物 ,可作为生物素缺乏的早期和敏感指标。
T4817 Methylmalonic acid

NSC 25201,MMA,Isosuccinic acid,甲基丙二酸,Methylpropanedioic acid,Methylmalonate

Others; Endogenous Metabolite Metabolism; Others
Methylmalonic acid (Isosuccinic acid) 是癌症患者缺乏维生素 B-12的指标。
T1301 Guaiacol

O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚

NF-κB; COX; Endogenous Metabolite Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
Guaiacol (2-Methoxyphenol) 是从小叶栲中提取的一种酚类,可抑制 LPS 刺激的COX-2表达和NF-κB 激活,具有抗炎活性。
TN6945 Lactic acid

2-hydroxypropanoic acid

Others Others
Lactic acid (2-hydroxypropanoic acid) 是糖酵解的产物,广泛存在与自然界中。Lactate acid 在体内收缩骨骼肌缺氧时会产生,可在完全有氧条件下被去除。Lactic acid 可作为危重病人的血流动力学指标。Lactic acid 具有抗肿瘤活性。
TN5171 Tricetin

Apoptosis; Others; Nrf2 Apoptosis; Immunology/Inflammation; Others
Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用(PPI)的强效竞争性抑制剂,通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路,保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1(PS-1)表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症,保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
T35049 Versicolorin A

Versicolorin

Versicolorin A is a potential indicator of aflatoxin contamination in corn stored in granary.
T39460 Mead acid

5,8,11-Eicosatrienoic acid

Mead acid, also known as 5,8,11-Eicosatrienoic acid, is an unsaturated fatty acid belonging to the Omega-9 series. It serves as an indicator of deficiency in essential fatty acids.
T40717 6-Methyluracil

Pseudothymine,6-甲基尿嘧啶

6-Methyluracil, also known as Pseudothymine, is a metabolite derived from Uracil. It serves as an indicator for the accumulation of acetoacetyl-CoA (AACoA). Additionally, 6-Methyluracil has been observed to possess antiradiation properties in vivo.
T15350 Fructosyl-lysine

Fructoselysine,果糖-赖氨酸

Others Others
Fructosyl-lysine is the precursor to glucosepane. Fructosyl-lysine is a lysine–arginine protein cross-link that can be an indicator in diabetes detection. Fructosyl-lysine is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction.
T22213 1,4-Diaminobutane Dihydrochloride

Others Others
1,4-Diaminobutane dihydrochloride, an endogenous metabolite, acts as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI). In addition, 1,4-Diaminobutane dihydrochloride is an important source of GABA.
TN4161 Goshonoside F1

Goshonoside F1是半糯米品种水稻的脂质代谢产物,可被当作培育优良水稻的一个指标。
TN3753 Dalbergioidin

Tyrosinase; ROS; Akt; PI3K; TGF-beta/Smad Cytoskeletal Signaling; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced ...

天然产物

orcinol
Cat.No: T3748
Synonym: 5-Methylresorcinol,苔黑素、苔黑酚、地衣酚,3,5-Dihydroxytoluene,3,5-二羟基甲苯,地衣酚,5-Methylresorcin,3,5-ToluenediolOrcin,5-Methyl-1,3-benzenediol,Orcin
Target: Others
L-Lactic acid
Cat.No: T4845
Synonym: 2-HYDROXYPROPIONIC ACID,L-乳酸,L-(+)-Lactic acid,(S)-2-Hydroxypropanoic acid
Target: Endogenous Metabolite, Antibacterial, Antibiotic
Bromothymol Blue
Cat.No: T18930
Synonym:
Target: Others
Butyrylcarnitine
Cat.No: T14840
Synonym:
Target: Endogenous Metabolite
Oleoylcarnitine
Cat.No: T12295
Synonym: Oleoyl-L-carnitine
Target: Endogenous Metabolite
3-Hydroxyisovaleric acid
Cat.No: T0613
Synonym: β-羟基异戊酸,Beta-Hydroxyisovaleric acid
Target: Others, Endogenous Metabolite
Methylmalonic acid
Cat.No: T4817
Synonym: NSC 25201,MMA,Isosuccinic acid,甲基丙二酸,Methylpropanedioic acid,Methylmalonate
Target: Others, Endogenous Metabolite
Guaiacol
Cat.No: T1301
Synonym: O-methylcatechol,2-hydroxyanisole,o-methoxyphenol,2-Methoxyphenol,愈创木酚
Target: NF-κB, COX, Endogenous Metabolite
Lactic acid
Cat.No: TN6945
Synonym: 2-hydroxypropanoic acid
Target: Others
Tricetin
Cat.No: TN5171
Synonym:
Target: Apoptosis, Others, Nrf2
Versicolorin A
Cat.No: T35049
Synonym: Versicolorin
Target:
Mead acid
Cat.No: T39460
Synonym: 5,8,11-Eicosatrienoic acid
Target:
6-Methyluracil
Cat.No: T40717
Synonym: Pseudothymine,6-甲基尿嘧啶
Target:
Fructosyl-lysine
Cat.No: T15350
Synonym: Fructoselysine,果糖-赖氨酸
Target: Others
1,4-Diaminobutane Dihydrochloride
Cat.No: T22213
Synonym:
Target: Others
Goshonoside F1
Cat.No: TN4161
Synonym:
Target:
Dalbergioidin
Cat.No: TN3753
Synonym:
Target: Tyrosinase, ROS, Akt, PI3K, TGF-beta/Smad
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