Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fructosyl-lysine is the precursor to glucosepane. Fructosyl-lysine is a lysine–arginine protein cross-link that can be an indicator in diabetes detection. Fructosyl-lysine is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction.
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
2 mg | ¥ 1,740 | 5日内发货 | ||
25 mg | ¥ 9,850 | 6-8周 | ||
50 mg | ¥ 12,800 | 6-8周 | ||
100 mg | ¥ 17,500 | 6-8周 |
产品描述 | Fructosyl-lysine is the precursor to glucosepane. Fructosyl-lysine is a lysine–arginine protein cross-link that can be an indicator in diabetes detection. Fructosyl-lysine is an amadori glycation product from the reaction of glucose and lysine by the Maillard reaction. |
体外活性 | Fructosyl-lysine (100 μM; 1 hour) contains a carbohydrate moiety and appears to be phosphorylated, it can be converted to glucose 6-phosphate in bacterial extracts in?E?.coli extracts. Fructosyl-lysine (25 mM; 25 hours) lets E. coli?growth at a rate of about one-third of that observed with glucose as a carbon source. Fructosyl-lysine (5 mM; 0.5 hours) catalyzes the ATP-dependent conversion of [14C]fructoselysine to anionic products showing the existence of a fructoselysine-kinase activity in E?.coli extracts [2]. |
体内活性 | In diabetic rats, Fructosyl-lysine and AGE residues are increased markedly in glomeruli, sciatic nerve, retina, and plasma protein [1]. |
别名 | Fructoselysine, 果糖-赖氨酸 |
分子量 | 308.33 |
分子式 | C12H24N2O7 |
CAS No. | 21291-40-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Fructosyl-lysine 21291-40-7 Others Fructoselysine Fructosyl lysine Fructosyllysine 果糖-赖氨酸 Inhibitor inhibitor inhibit