552
2
38
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11346L |
G3-C12 acetate(848301-94-0 free base)
|
Galectin | Immunology/Inflammation |
G3-C12 acetate(848301-94-0 free base) 显示出抗癌活性。是一种半乳糖凝集素 3 结合肽,Kd 为 88 nM。 | |||
T11346 |
G3-C12
|
Others | Others |
G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM. | |||
TP1294 |
G3-C12 TFA (848301-94-0 free base)
G3-C12 TFA |
||
G3-C12 TFA Salt is a specific galectin-3 binding peptide with Ksubdsub of 88 nM and shows anticancer activity. | |||
T37834 |
G3-CNP
|
||
G3-CNP is a colorimetric substrate for α-amylases.1Upon hydrolysis by α-amylases, 2-chloro-4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. G3-CNP has been used to characterize the activity of human pancreatic or salivary amylase. | |||
T64584 |
tBuBrettPhos Pd G3
|
||
[(2-Di-tert-butylphosphino-3,6-dimethoxy-2',4',6'-triisopropyl-1,1'-biphenyl)-2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64584,CAS号为 1536473-72-9。 | |||
T124100 |
Platycoside G3
|
||
Platycoside G3 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124100,CAS号为 849758-44-7。 | |||
T67255 | AdBrettPhos Pd G3 | ||
AdBrettPhos Pd G3 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67255。 | |||
T23583 |
58-G3
58G3 |
||
58-G3 is an agonist of methuselah (Mth)-specific that acts by inducing dose-dependent calcium elevation and membrane translocation of β-arrestin2. | |||
T64623 |
SPhos Pd G3
|
||
(2-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl)[2-(2'-amino-1,1'-biphenyl)]palladium(II) methanesulfonate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64623,CAS号为 1445085-82-4。 | |||
T67257 | DavePhos-Pd-G3 | ||
Methanesulfonato[2-(dicyclohexylphosphino)-2'-(N,N-dimethylamino)-1,1'-biphenyl](2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67257。 | |||
T67253 | DPPF Pd G3 | ||
Methanesulfonato[1,1'-bis(diphenylphosphino)ferrocene)](2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67253。 | |||
T64791 |
APhos Pd G3
|
||
APhos Pd G3 在生命科学相关研究中具有广泛的应用。 | |||
T64446 | RockPhos Pd G3 | ||
[2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC][bis(1,1-dimethylethyl)[3-methoxy-6-methyl-2',4',6'-tris(1-methylethyl)[1,1'-biphenyl]-2-yl]phosphine-κP](methanesulfonato-κO)palladium 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64446。 | |||
T75986 |
G3-C12 TFA
|
||
G3-C12 (TFA) 是 galectin-3 结合肽,Kd 值为 88 nM,具有抗肿瘤活性。 | |||
T67262 | PCy3 Pd G3 | ||
Methanesulfonato(tricyclohexylphosphine)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67262。 | |||
T64762 |
P(t-Bu)3 Pd G3
|
||
P(t-Bu)3 Pd G3 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64762,CAS号为 1445086-17-8。 | |||
T66570 | t-BuXPhos Pd G3 | ||
Methanesulfonato(2-di-t-butylphosphino-2',4',6'-tri-i-propyl-1,1'-biphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T66570。 | |||
T64532 | Rac-Binap Pd G3 | ||
[2'-(Amino-κN)[1,1'-biphenyl]-2-yl-κC][[2'-(diphenylphosphino)[1,1'-binaphthalen]-2-yl]diphenylphosphine-κP](methanesulfonato-κO)palladium 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64532。 | |||
T64620 | cataCXium A Pd G3 | ||
Methanesulfonato(diadamantyl-n-butylphosphino)-2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T64620。 | |||
T67254 | N-XantPhos Pd G3 | ||
Methanesulfonato[4,6-bis(diphenylphosphino)phenoxazine](2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67254。 | |||
T67252 | 4Me t-BuXPhos Pd G3 | ||
Methanesulfonato(2-di-t-butylphosphino-3,4,5,6-tetramethyl-2',4',6'-tri-i-propylbiphenyl)(2'-amino-1,1'-biphenyl-2-yl)palladium(II) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T67252。 | |||
T67259 |
Josiphos SL-J009-1 Pd G3
|
||
Josiphos SL-J009-1 Pd G3 在生命科学相关研究中具有广泛的应用。 | |||
T14220 |
Amine-PEG3-Biotin
|
Others | Others |
Amine-PEG3-Biotin 可用作信号放大标记。 | |||
T17909 |
(S,R,S)-AHPC-PEG3-N3
VHL Ligand-Linker Conjugates 8,VH032-PEG3-N3,E3 ligase Ligand-Linker Conjugates 12 |
Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | Others; PROTAC |
(S,R,S)-AHPC-PEG3-N3 (VHL Ligand-Linker Conjugates 8) 包含基于 (S,R,S)-AHPC 的 VHL 配体和 3 个单元 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T14591 |
Biotin-PEG3-azide
N-[2-[2-[2-(2-叠氮乙氧基)乙氧基]乙氧基]乙基]生物素胺 |
Others; PROTAC Linker | Others; PROTAC |
Biotin-PEG3-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成 | |||
T22794 |
G36
G-36 |
Estrogen Receptor/ERR | Endocrinology/Hormones |
G36是一种细胞可渗透的G 蛋白偶联雌激素受体(GPER/GPR30)的非甾体拮抗剂。G36抑制17β-雌二醇或GPER 选择性激动剂G-1的激活(IC50分别为112和165 nM)。G36对ERα或ERβ均无可检测的结合活性。G36通过GPER 阻断由雌激素触发的PI3K 的激活或钙动员,并且它通过雌激素或G-1而不是通过EGF 抑制ERK 的激活。 | |||
T14741 |
Boc-NH-PEG3-CH2COOH
5,8,11-三氧杂-2-氮杂十三烷二酸 1-叔丁酯 |
PROTAC Linker | PROTAC |
Boc-NH-PEG3-CH2COOH 是基于 PEG 的 PROTAC linker,用于合成 PROTAC。 | |||
T7758 |
Thalidomide-O-amido-PEG3-C2-NH2 TFA
E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA) |
Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) 包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T18184 |
m-PEG3-SH
M-PEG3-Thiol,2-(2-(2-Methoxyethoxy)Ethoxy)Ethanethiol |
Others; PROTAC Linker | Others; PROTAC |
m-PEG3-SH (M-PEG3-Thiol) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T38888 |
Azide-PEG3-Desthiobiotin
Azide-PEG3-Desthiobiotin |
||
Azide-PEG3-Desthiobiotin 是一种 属于 PEG 类的PROTAC linker,可用于合成 PROTAC 分子。 | |||
T17575 |
Biotin-PEG3-OH
生物素三聚乙二醇羟基 |
Others; PROTAC Linker | Others; PROTAC |
Biotin-PEG3-OH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16437 |
PC Biotin-PEG3-alkyne
|
Others | Others |
PC Biotin-PEG3-alkyne 是一种 ADC 连接剂,可裂解的 3 单元 PEG,还可以用于合成抗体药物共轭物 (ADC)。 | |||
T7701 |
Boc-NH-PEG3
PROTAC Linker 10,2-[2-(2-T-BOC-氨基乙氧基)乙氧基]乙醇 |
Others; PROTAC Linker | Others; PROTAC |
Boc-NH-PEG3 (PROTAC Linker 10) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 的合成分子。 | |||
T15076 |
DBCO-S-S-PEG3-biotin
生物素-PEG3-二硫-DBCO |
Others; PROTAC Linker | Others; PROTAC |
DBCO-S-S-PEG3-biotin 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17791 |
DBCO-PEG3-NHS ester
|
Others | Others |
DBCO-PEG3-NHS ester是一种可降解的 ADC linker,可用于合成抗体偶联活性分子 。 | |||
T9384 |
Pomalidomide-PEG3-OH
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]amino]- |
PROTACs | PROTAC |
Pomalidomide-PEG3-OH 能够合成用于靶向蛋白质降解和 PROTAC(蛋白水解靶向嵌合体)技术的分子。 | |||
T10777 |
CG347B
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
CG347B 是一种选择性HDAC6抑制剂。 | |||
T16605 |
Propargyl-PEG3-acid
丙炔基-二聚乙二醇-羧酸 |
PROTAC Linker | PROTAC |
Propargyl-PEG3-acid 是一种不可切割的,含 3 个单元 PEG 的 ADC 接头,也是一种基于 PEG 的 PROTAC 接头,可用于合成 6-OHDA-PEG3-yne。 6-OHDA-PEG3-yne 包含 6-OHDA 和炔丙基-PEG3-酸。 | |||
T17677 |
Boc-NH-PEG3-NHS ester
氨基叔丁酯-三聚乙二醇-NHS 酯 |
Others; PROTAC Linker | Others; PROTAC |
Boc-NH-PEG3-NHS ester 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18629 |
PEG3-O-CH2COOH
PROTAC Linker 8,三聚乙二醇-乙酸 |
Others; PROTAC Linker | Others; PROTAC |
PEG3-O-CH2COOH (PROTAC Linker 8) 是一种属于 PEG 类的 PROTAC linker,可用于 SNIPER 分子的合成。 | |||
T17501 |
Azido-PEG3-azide
1,11-二叠氮基-3,6,9-三氧杂十一烷 |
Others; PROTAC Linker | Others; PROTAC |
Azido-PEG3-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T7101 |
Tyrphostin AG30
Tyrphostin AG30(AG30),酪氨酸磷酸化抑制剂 AG 30 |
EGFR; Tyrosine Kinases | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Tyrphostin AG30 (AG30) 是一种有效的蛋白质酪氨酸激酶 (PTK) 抑制剂,选择性地抑制 c-ErbB 的自我更新诱导,并能抑制原发性红细胞 c-ErbB 激活 STAT5。 | |||
T17637 |
BM-PEG3
1,11-Bis-maleimidotetraethyleneglycol,1,11-双马来酰亚胺基-3,6,9-三氧代十一烷 |
Others; PROTAC Linker | Others; PROTAC |
BM-PEG3 (1,11-Bis-maleimidotetraethyleneglycol) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16302 |
NH-bis(PEG3-azide)
|
Others | Others |
NH-bis(PEG3-azide) 是一种属于 PEG 类的 PROTAC 连接体,可用于合成 PROTAC 分子。 | |||
T73384 |
GLPG3970
|
||
GLPG3970 是一类首创的 SIK2/SIK3抑制剂。GLPG3970 可用于炎症和自身免疫性疾病的研究。 | |||
T21598L |
G3335 Acetate
G3335 Acetate (36099-95-3 free base) |
PPAR | DNA Damage/DNA Repair; Metabolism |
G3335 Acetate 被发现是一种新型 PPARgamma 拮抗剂。 | |||
T17722 |
Cbz-NH-PEG3-CH2COOH
苯甲氧羰酰基二聚乙二醇羧乙基 |
Others; PROTAC Linker | Others; PROTAC |
Cbz-NH-PEG3-CH2COOH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T9382 |
Thalidomide-NH-C2-PEG3-OH
H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]- |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是 E3 连接酶配体-linker 偶联物,可用于合成 PROTAC BCL-XL 降解剂 XZ739。 | |||
T14797 |
Bromo-PEG3-C2-acid
溴代-三聚乙二醇-羧酸 |
PROTAC Linker | PROTAC |
Bromo-PEG3-C2-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T40023 |
Pomalidomide-PEG3-CO2H
Thalidomide-NH-PEG3-propionic acid |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Pomalidomide-PEG3-CO2H (Thalidomide-NH-PEG3-propionic acid) 是一种由 E3 连接酶配体和连接体组成的偶联物,结合了基于 Thalidomide 的 Cereblon 配体和 3 个单元 PEG Linker。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3812 |
(20R)-Ginsenoside Rg3
人参皂甙 RG3,(20R)-人参皂苷Rg3,20(R)-Ginsenoside Rg3,(20R)Ginsenoside Rg3,20(R)-Propanaxadiol |
Others | Others |
(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) 是一种人参根中的化合物,具有抑制血管内皮细胞增生(IC50= 10 nM)和抗肿瘤作用。 | |||
T3402 |
20(S)-Ginsenoside Rg3
20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3 |
EGFR; Beta Amyloid; Potassium Channel; NF-κB; COX; Sodium Channel; Endogenous Metabolite | Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors |
20(S)-Ginsenoside Rg3 (Rg3) 是红参的主要成分,通过抑制肿瘤细胞的粘附和侵袭来抑制肿瘤细胞肺转移。它抑制Na+和hKv1.4通道,IC50分别为 32.2±4.5 和 32.6±2.2 μM。它还抑制Aβ,NF-κB 活性和COX-2表达,抑制人脐静脉内皮细胞的增殖并具有抗血管生成活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01606 |
BAG6 Protein, Human, Recombinant (His & Myc)
BAG-6,Protein G3,BAG family molecular chaperone reg... |
Human | Baculovirus Insect Cells |
BAG6 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 38.7 kDa and the accession number is P46379. | |||
TMPH-01605 |
BAG6 Protein, Human, Recombinant (E. coli, His & Myc)
BAT3,BAG6,HLA-B-associated transcript 3,BCL2-associated atha... |
Human | E. coli |
BAG6 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.7 kDa and the accession number is P46379. | |||
TMPK-00673 |
SG3/Secretogranin 3 Protein, Cynomolgus, Recombinant (His)
SCG3,Secretogranin-3,UNQ2502/PRO5990,SGIII,Secretog... |
Cynomolgus | HEK293 Cells |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Cynomolgus... | |||
TMPJ-00582 |
PRG3 Protein, Human, Recombinant (His)
Prepro-MBPH,Prepro-Major Basic Protein Homolog,Eosinophil Ma... |
Human | HEK293 Cells |
Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain. Proteoglycans are a major component of the animal extracellular matrix. PRG3 localizes to the eosinophil secondary granule and is expressed in bone marrow, not detected in placenta. PRG3 has similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, PRG3 can stimulate neutrophil superoxide production and IL8 release, histamine an... | |||
TMPH-01998 |
G3BP1 Protein, Human, Recombinant (His)
|
Human | E. coli |
G3BP1 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-01135 |
PSG3 Protein, Human, Recombinant (His)
PS-Beta-G-3,Pregnancy-specific β-1-glycoprotein 3,Carcinoemb... |
Human | HEK293 Cells |
Pregnancy-specific beta-1-glycoprotein 3 is also known as Carcinoembryonic Antigen SG5,Pregnancy-Specific Glycoprotein 3 ,PS-Beta-G-3, PSBG-3.It belongs to the immunoglobulin superfamily. CEA family.It synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular Cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, Members of the CEA family consist o... | |||
TMPY-00071 |
Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is A0A068J419. | |||
TMPK-01485 |
HLA-A*01:01&B2M&DSG3 (YTDNWLAVY) Monomer Protein, Human, MHC (His & Avi)
CDHF6,DG3,DSG3,PVA,DSG-3,Desmoglein-3 |
Human | HEK293 Cells |
DSG3 is overexpressed in head neck cancer and is a potential molecular target for inhibition of oncogenesis. DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. These findings suggest that DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. | |||
TMPH-03365 |
REG3A Protein, Rat, Recombinant (E.coli, His)
|
Rat | E. coli |
Bactericidal C-type lectin. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. REG3A Protein, Rat, Recombinant (E.coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.5 kDa and the accession number is P35231. | |||
TMPJ-00057 |
REG3G Protein, Human, Recombinant (hFc)
PAP-1B,REG3G,Regenerating islet-derived protein III... |
Human | HEK293 Cells |
Pancreatitis-associated protein IB, Regenerating islet-derived protein III-gamma, is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the pancreas and also expressed in testis, but not found in small intestine. This protein might be a stress protein involved in the control of bacterial proliferation. | |||
TMPY-02895 |
IgG3 Protein, Human, Recombinant
IGHG3 |
Human | HEK293 Cells |
IgG3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 31.2 kDa and the accession number is P01860. | |||
TMPY-01479 |
SPG3A Protein, Human, Recombinant (GST)
HSN1D,atlastin GTPase 1,FSP1,atlastin1,GBP3,SPG3,SP... |
Human | Baculovirus Insect Cells |
Atlastin-1, also known as Spastic paraplegia 3 protein A, Guanine nucleotide-binding protein 3, GTP-binding protein 3, GBP3, ATL1 and SPG3A, is a multi-pass membrane protein which belongs to theGBP family and atlastin subfamily. ATL1 / SPG3A is expressed predominantly in the adult and fetal central nervous system. Expression of ATL1 / SPG3A in adult brain is at least 5-fold higher than in other tissues. ATL1 / SPG3A is detected predominantly in pyramidal neurons in the cerebral cortex and... | |||
TMPY-01847 |
REG3D Protein, Mouse, Recombinant (His)
Reg3d,regenerating islet-derived 3 delta,Ingaprp,MG... |
Mouse | HEK293 Cells |
Regenerating islet-derived 3 delta (REG3D) is a member of the secreted Reg superfamily and contains one typical C-type lectin domain. Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on t... | |||
TMPK-00871 |
DSG3 Protein, Human, Recombinant (His)
CDHF6,SG3,DSG-3,DSG3,Desmoglein-3,PVA |
Human | HEK293 Cells |
To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Human, Recombinant (His) is expressed in HEK2... | |||
TMPY-03994 |
SG3/Secretogranin 3 Protein, Human, Recombinant (His)
secretogranin III,SGIII,UNQ2502/PRO5990 |
Human | HEK293 Cells |
SG3/Secretogranin 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is AAH14539.1. | |||
TMPY-04300 |
NRG3 Protein, Human, Recombinant (His)
pro-NRG3,neuregulin 3,HRG3 |
Human | HEK293 Cells |
NRG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.5 kDa and the accession number is D9ZHP7. | |||
TMPY-01561 |
PIG3 Protein, Human, Recombinant (His)
TP53I3,PIG3,tumor protein p53 inducible protein 3 |
Human | E. coli |
Nutlin-3 variably induces apoptosis and cell cycle arrest in cancer cells while it shows low/absent cytotoxicity in normal cells, Nutlin-3 is a promising anti-cancer agent, which exhibits activity against a variety of cancers, including acute myeloid leukemia (AML). The important role of TP53I3/PIG3 in mediating the apoptotic activity of Nutlin-3 was underlined by knock-down experiments with siRNA specific for TP53I3/PIG3, which resulted in a significant decrease in the pro-apoptotic activity of... | |||
TMPY-01406 |
REG3G Protein, Human, Recombinant (His)
UNQ429,PAP-1B,LPPM429,REG-III,regenerating islet-derived 3 γ... |
Human | HEK293 Cells |
Regenerating gene (Reg), first isolated from a regenerating islet cDNA library, encodes a secretory protein with a growth stimulating effect on pancreatic beta cells. Reg and Reg-related genes which were expressed in various organs have been revealed to constitute a multigene family, the Reg family, which consists of four subtypes (types I, II, III, IV) based on the primary structures of the encoded proteins of the genes, which are associated with tissue repair and have been directly implicated ... | |||
TMPH-02534 |
BAG3 Protein, Mouse, Recombinant (His)
Bcl-2-associated athanogene 3,Bag3,Bcl-2-binding pr... |
Mouse | P. pastoris (Yeast) |
BAG3 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is Q9JLV1. | |||
TMPH-03368 |
SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc)
|
Rat | E. coli |
Member of the granin protein family that regulates the biogenesis of secretory granules. Acts as a sorting receptor for intragranular proteins including chromogranin A/CHGA. May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway. SG3/Secretogranin 3 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.2 kDa and the accessio... | |||
TMPK-00726 |
DSG3 Protein, Mouse, Recombinant (His)
SG3,PVA,DSG3,CDHF6,Desmoglein-3,DSG-3 |
Mouse | HEK293 Cells |
To identify genes that could potentially serve as molecular therapeutic markers for human head and neck cancer (HNC),DSG3 is identified overexpressed in HNC, with the degree of overexpression associated with clinicopathologic features of the tumor. Inhibition of DSG3 significantly suppresses carcinogenic potential in cellular and in vivo animal studies. DSG3 is a potential molecular target in the development of adjuvant therapy for HNC. DSG3 Protein, Mouse, Recombinant (His) is expressed in HEK2... | |||
TMPH-03658 |
Vaccinia virus (strain Copenhagen) Ag35 Protein (His & Myc)
|
VACV | E. coli |
Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell. Vaccinia virus (strain Copenhagen) Ag35 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 40.3 kDa and the accession number is P20497. | |||
TMPK-01122 |
SG3/Secretogranin 3 Protein, Human, Recombinant (aa 20-468, His)
SCG3,Secretogranin III,UNQ2502/PRO5990,Secretograni... |
Human | HEK293 Cells |
Secretogranin III (Scg3) is a member of the granin protein family that regulates the biogenesis of secretory granules. Scg3 was recently discovered as an angiogenic factor, expanding its functional role to extrinsic regulation. Unlike many other known angiogenic factors, the pro-angiogenic actions of Scg3 are restricted to pathological conditions. Among thousands of quantified endothelial ligands, Scg3 has the highest binding activity ratio to diabetic vs. SG3/Secretogranin 3 Protein, Human, Rec... | |||
TMPY-01090 |
REG3A Protein, Mouse, Recombinant (His)
regenerating family member 3 α,Rega3a,regenerating family me... |
Mouse | HEK293 Cells |
REG3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is O09037. | |||
TMPY-03134 |
REG3A Protein, Rat, Recombinant (His)
regenerating family member 3 α,Pap2,regenerating family memb... |
Rat | HEK293 Cells |
REG3A Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.9 kDa and the accession number is BAA04904.1. | |||
TMPY-01336 |
REG3A Protein, Human, Recombinant (His)
HIP/PAP,INGAP,REG3,PAP1,PAP-H,regenerating family m... |
Human | HEK293 Cells |
REG3A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is Q06141-1. | |||
TMPJ-01354 |
ATG3 Protein, Human, Recombinant
ATG3,Ubiquitin-like-conjugating enzyme ATG3 |
Human | E. coli |
Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential fo... | |||
TMPY-00192 |
NRG3 Protein, Human, Recombinant (hFc)
pro-NRG3,neuregulin 3,HRG3 |
Human | HEK293 Cells |
NRG3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.7 kDa and the accession number is B9EGV5. | |||
TMPY-04675 |
SG3/Secretogranin 3, Mouse, Recombinant (His)
AI385542,SgIII,1B1075,Chgd,secretogranin III |
Mouse | HEK293 Cells |
SG3/Secretogranin 3, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.4 kDa and the accession number is P47867-1. | |||
TMPH-02019 |
REG3A Protein, Human, Recombinant (GST)
|
Human | E. coli |
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. REG3A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.6 kDa and the accession number is Q06141. | |||
TMPH-02535 |
BAG3 Protein, Mouse, Recombinant (His & SUMO)
Bcl-2-associated athanogene 3,Bis,BAG-3,BAG family molecular... |
Mouse | E. coli |
BAG3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 77.7 kDa and the accession number is Q9JLV1. | |||
TMPY-00307 |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His)
|
EBOV | HEK293 Cells |
Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is A0A068J419. | |||
TMPY-03673 |
REG3B Protein, Mouse, Recombinant (His)
Pap,HIP,REG-III,PAP1 |
Mouse | HEK293 Cells |
Expression of REG3B was sufficient to inhibit cytokine-induced activation of STAT3 in IECs. The human REG3beta protein, the functional counterpart of mouse REG3B, inhibited STAT3 activity in human 293T cells, and its expression level in colorectal tumors correlated inversely with pSTAT3 level and survival times of patients. REG3B negatively regulates cytokine-induced activation of STAT3 in colon epithelial cells. This pathway might be targeted in patients with colitis to reduce carcinogenesis. | |||
TMPH-01217 |
DSG3 Protein, Human, Recombinant (E. coli, His)
130 kDa pemphigus vulgaris antigen (PVA),CDHF6,DSG3... |
Human | E. coli |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. | |||
TMPH-02879 |
REG3G Protein, Mouse, Recombinant (His)
|
Mouse | P. pastoris (Yeast) |
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regula... | |||
TMPY-02696 |
IgG3 Protein, Mouse, Recombinant
IgG3-Fc,IgG3 |
Mouse | HEK293 Cells |
IgG3 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P03987-2. | |||
TMPH-00521 |
G3P Protein, Enterobacteria phage M13, Recombinant (His)
|
Enterobacteria phage M13 | P. pastoris (Yeast) |
Plays essential roles both in the penetration of the viral genome into the bacterial host via pilus retraction and in the extrusion process. During the initial step of infection, G3P mediates adsorption of the phage to its primary receptor, the tip of host F-pilus. Subsequent interaction with the host entry receptor tolA induces penetration of the viral DNA into the host cytoplasm. In the extrusion process, G3P mediates the release of the membrane-anchored virion from the cell via its C-terminal... | |||
TMPY-03133 |
REG3A Protein, Rat, Recombinant (hFc)
Pap2,REG3A,regenerating family member 3 alpha,Re |
Rat | HEK293 Cells |
REG3A Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is BAA04904.1. |