49
5
87
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TP1530L |
YRGDS Fibronectin Fragment acetate
YRGDS Fibronectin Fragment acetate(134282-68-1 free base) |
Others | Others |
YRGDS Fibronectin Fragment acetate (YRGDS Fibronectin Fragment acetate (134282-68-1 free base))(134282-68-1 free base) 是一种纤连蛋白片段乙酸酯,是一种粘附肽,对凝血酶刺激的血小板具有很强的结合亲和力。它是由序列组成的 RGD。 | |||
TP1555L1 |
Fibronectin Active Fragment Control acetate
Fibronectin Active Fragment Control acetate(97461-84-2 Free base) |
||
Fibronectin Active Fragment Control acetate 是纤连蛋白的活性片段,这是一种糖蛋白。 | |||
TP1526L1 |
Fibronectin CS1 Peptide acetate
|
Others | Others |
Fibronectin CS1 Peptide acetate 存在于 III 型同源连接段 (IIICS) 以及 C-274(细胞结合结构域)中。 Fibronectin CS1 Peptide 缺乏含有 Arg-Gly-Asp 的结构域,在自发和实验性转移模型中积极抑制肿瘤转移。 | |||
TP1153L |
Fibronectin Adhesion-promoting Peptide acetate
Fibronectin Adhesion-promoting Peptide acetate(125720-21-0 free base),Heparin Binding Peptide acetate |
Others | Others |
Fibronectin Adhesion-promoting Peptide acetate (Heparin Binding Peptide acetate)(125720-21-0 free base) 是在纤连蛋白的羧基末端肝素结合结构域中发现的肝素结合氨基酸序列之一。 | |||
TP1526 |
Fibronectin CS1 Peptide
|
||
he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontan | |||
TP1530 |
YRGDS Fibronectin Fragment
|
||
This is a fibronectin fragment, an adhesion peptide that displays strong binding affinity to thrombin-stimulated platelets. It is RGD consisting of sequence. | |||
TP1555 |
Fibronectin Active Fragment Control
|
||
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins.In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin | |||
TP1153 |
Fibronectin Adhesion-promoting Peptide
Heparin Binding Peptide |
||
Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. | |||
TP1152 |
Fibronectin Adhesion-promoting Peptide TFA
Heparin Binding Peptide TFA |
||
Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into lar | |||
T10366 |
Arg-Gly-Asp-Ser
Fibronectin tetrapeptide,RGDS peptide |
Others | Others |
Arg-Gly-Asp-Ser is an integrin-binding sequence that inhibits integrin receptor function. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, MMP-9, and iNOS | |||
TP1043 |
Arg-Gly-Asp-Ser (TFA)(91037-65-9,free)
Fibronectin tetrapeptide (TFA),RGDS peptide (TFA),Arg-Gly-Asp-Ser (TFA) |
||
Arg-Gly-Asp-Ser (TFA) is an integrin binding sequence that inhibits integrin receptor function. | |||
T82403 |
Fibronectin Type III Connecting Segment Fragment 1-25
|
||
Fibronectin Type III Connecting Segment Fragment 1-25,一种多肽,主要作用于黑色素瘤细胞的粘附,并在鸡的周围神经系统发育中扮演关键角色。 | |||
T5329 |
Trandolapril
|
Angiotensin-converting Enzyme (ACE) | Metabolism |
Trandolapril 是 Trandolaprilat 的前体药物。Trandolapril 是一种口服血管紧张素转换酶抑制剂,在高血压和充血性心力衰竭及心肌梗死领域有研究价值。 | |||
T7566 |
GRGDSPK
EMD 56574 |
Others | Others |
GRGDSPK (EMD 56574) 是一种包含精氨酸-甘氨酸-天冬氨酸 (RGD) 的多肽,也是一种竞争性且可逆的抑制肽,可抑制整联蛋白-纤连蛋白结合,可用于整联蛋白在骨形成和吸收中作用的研究。 | |||
T7566L1 |
GRGDSPK acetate
GRGDSPK acetate(111119-28-9 Free base) |
Beta Amyloid | Neuroscience |
GRGDSPK acetate 显示出对整合素-纤连蛋白结合的抑制活性,可用于研究整合素在骨形成和吸收中的作用。 | |||
TP1459L |
Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
|
Integrin | Cytoskeletal Signaling |
Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base) 是一种源自纤连蛋白的细胞结合区域的细胞结合蛋白结构域。 | |||
TP1447L1 |
Arg-Gly-Asp-Cys acetate
Arg-Gly-Asp-Cys acetate(109292-46-8 free base),RGDC acetate |
Others | Others |
Arg-Gly-Asp-Cys acetate 抑制血小板聚集和纤维蛋白原结合。 Arg-Gly-Asp-Cys acetate 是纤连蛋白与细胞粘附分子的结合基序。 | |||
T61389 |
TGFβ1-IN-1
|
TGF-beta/Smad | Stem Cells |
TGFβ1-IN-1 是一种具有口服活性的 TGF-β1 抑制剂,抑制 TGF-β1 诱导的纤维化标志物(α-SMA 和纤连蛋白)的产生,可用于研究癌症和自身免疫疾病。 | |||
T27347 |
Fonsartan free acid
HR720,HOE720,HR-720,HOE-720 |
||
Fonsartan is an angiotensin receptor antagonist. Fonsartan inhibits the angiotensin II-induced trophic effects, fibronectin release and fibronectin-EIIIA+ expression in rat aortic vascular smooth muscle cells in vitro. | |||
T26265 |
TG53
TG-53,TG 53 |
||
TG53 is a tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction inhibitor. | |||
T40361 |
Integrin Binding Peptide
|
||
Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels. | |||
T69203 |
HMR1031
|
||
HMR1031 is a potent and specific integrin α4ß1 or very late antigen 4 (VLA-4) receptor antagonist which binds to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin. | |||
T37047 |
12(S)-HETE
|
||
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. [1] It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1μM181M.[2][3] | |||
TP1447 |
Arg-Gly-Asp-Cys
RGDC |
||
Arg-Gly-Asp-Cys is the binding motif of fibronectin and cell adhesion molecules, which can inhibit platelet aggregation and fibrinogen binding. | |||
T39655 |
Arg-Gly-Asp-Cys TFA
|
||
Arg-Gly-Asp-Cys TFA serves as the binding motif through which fibronectin interacts with cell adhesion molecules. This compound has the ability to hinder platelet aggregation and fibrinogen binding. | |||
TP1459 |
Gly-Arg-Gly-Asp-Ser
|
||
Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin. | |||
T78029 |
REDV TFA
|
Integrin | Cytoskeletal Signaling |
REDV TFA为纤维连接蛋白(IIICS)区域CS5位点的活性片段,其通过整合素α4β1的结合介导细胞与血浆纤维连接蛋白IIICS区域的粘附作用,适用于细胞粘附研究。 | |||
TP2101 |
Z-VRPR-FMK trifluoroacetate salt
|
||
Irreversible MALT1 inhibitor. Suppresses T cell activation-induced cleavage of Bcl-10 in a dose-dependent manor. Reduces Jurkat cell adhesion to fibronectin. Cell permeable. | |||
T76286 |
REDV
|
||
REDV 是纤连蛋白交替剪接的 III 型连接段 (IIICS) 区域的 CS5 位点内的活性序列。REDV 可以通过结合整合素α4β1介导与血浆纤连 IIICS 区域的粘附。REDV 可用于细胞粘附的研究。 | |||
T13249 |
UK-370106
|
MMP | Proteases/Proteasome |
UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM). | |||
TP1582 |
Gly-Arg-Gly-Asp-Ser (TFA)(96426-21-0,free)
Gly-Arg-Gly-Asp-Ser (TFA) |
||
Gly-Arg-Gly-Asp-Ser (GRGDS) is a cell binding protein domain derived from the cell-binding region of fibronectin. Osteopontin uses this motif for cell adhesion. | |||
T41151 |
K34c
|
||
K34c is a potent and selective α5β1 integrin inhibitor (IC50 = 3.1 nM). K34c inhibits cell survival and migration, inhibits p53-dependent senescence induced by Temozolomide or Ellipticine and promotes apoptosis in U87MG cells. K34c also prevents TGFβ-induced infiltrationin vivoand reduces cell adhesion on fibronectin. | |||
T36930 |
Palmitoyl Tetrapeptide-7 (acetate)
|
||
Palmitoyl tetrapeptide-7 is a cosmeceutical peptide that stimulates type I collagen, fibronectin, and hyaluronic acid production in skin.1Formulations containing palmitoyl tetrapeptide-7 have been used in the treatment of photoaging, dark circles, and undereye puffiness. 1.Bucay, V.W., and Day, D.Adjunctive skin care of the brow and periorbital regionClin. Plast. Surg.40(1)225-236(2013) | |||
T81186 |
SDGR
|
||
SDGR是一种四肽,含有Ser-Asp-Gly-Arg序列,能够有效抑制纤连蛋白介导的细胞附着。 | |||
T40958 |
Milategrast
E6007 |
||
Milategrast is a chemical compound that functions as a potent cell adhesion inhibitor and cell infiltration inhibitor. In vitro studies have demonstrated its ability to effectively inhibit the adhesion of Jurkat cells to human fibronectin, with an IC50 value of less than 5 μM. | |||
T82887 |
Bifikafusp alfa
L19-IL2 |
||
Bifikafusp alfa (L19-IL2) 是一种由人类L19抗体与细胞因子白介素2 (IL2) 结合而成的免疫融合蛋白,特异性针对纤维连接蛋白的EDB区域,并表现出抗癌活性。 | |||
T41150 |
EMD 527040 hydrochloride
|
||
EMD 527040 hydrochloride 是一种有效的整合素α V β 6抑制剂。EMD 527040 hydrochloride 对α V β 6与纤维连接蛋白的结合和表达α V β 6的细胞与纤维连接蛋白的附着有抑制作用,IC 50值分别为6 nM 和1.6 μM。EMD 527040 hydrochloride 在胆道纤维化动物模型中显示出抗纤维化活性,并在体内具有活性。 | |||
TP2186 |
PalMitoyl Tripeptide-1
|
Others | Others |
PalMitoyl Tripeptide-1 对人体皮肤成纤维细胞中胶原蛋白、纤连蛋白和透明质酸的合成有影响,可用于制备抗衰老化妆品。 | |||
T82359 |
G-{d-Arg}-GDSP
|
||
G-{d-Arg}-GDSP为RGD多肽类似物,具有与整合素粘附受体结合的能力,能够抑制细胞对纤维连接蛋白的附着及破骨细胞的重吸收。 | |||
T76289 |
EILEVPST
|
||
EILEVST为重组人纤连蛋白衍生的低分子量肽片段。该化合物能够促进细胞类型特异性α4整合素介导的粘附,适用于血栓形成相关研究。 | |||
T81005 |
Tetrapeptide-4
|
||
Tetrapeptide-4,一种护肤产品中常用的肽,具备减少皱纹与增强胶原蛋白、弹性蛋白及纤连蛋白的功能,展现出显著的抗衰老特性。 | |||
TP2186L1 |
PalMitoyl Tripeptide-1 hydrochloride
PalMitoyl Tripeptide-1 hydrochloride(147732-56-7 Free base),棕榈酰三肽-1盐酸盐 |
Others | Others |
PalMitoyl Tripeptide-1 hydrochloride (PalMitoyl Tripeptide-1 hydrochloride (147732-56-7 Free base)) 对人体皮肤成纤维细胞中胶原蛋白、纤连蛋白和透明质酸的合成有影响,可用于制备抗衰老化妆品。 | |||
T38363 |
MeOSuc-AAPV-pNA
|
||
Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to destroy pathogens. Evaluating these enzymes is helpful to understanding inflammatory autoimmune processes. MeOSuc-AAPV-pNA is a highly sensitive peptide substrate that is hydrolyzed by b... | |||
T75765 |
GRGDSPK TFA
|
||
GRGDSPK TFA (EMD 56574 TFA) 是一种含有精氨酸-甘氨酸-天冬氨酸 (RGD) 序列的多肽。作为竞争性且可逆的抑制剂,它能够抑制整联蛋白与纤连蛋白的结合,用于探究整联蛋白在骨形成及吸收过程中的功能。 | |||
T83736 |
RTDLDSLRTYTL TFA
|
||
RTDLDSLRTYTL是一种αVβ6整合素配体。它选择性地抑制纤维连接蛋白与αVβ6整合素的结合,相比之下,对于纤维连接蛋白与αVβ3或αVβ5以及纤维蛋白原与αIIβ3的结合则几乎不产生影响(IC50分别为0.02, >50, >50, 和 >50 µM)。此外,RTDLDSLRTYTL还能以浓度依赖的方式抑制HT-29结肠癌细胞与纤维连接蛋白的结合。 | |||
TP1910 |
CALP1
|
||
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibit | |||
T37631 |
tetranor-12(S)-HETE
|
||
12(S)-HETE is a product of arachidonic acid metabolism through the 12-lipoxygenase pathway. It is primarily found in platelets, leukocytes, and to a lesser extent in smooth muscle cells. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix. tetranor-12(S)-HETE is the major β-oxidation product resulting from peroxisomal metabolism of 12(S)-HETE in numerous tissues, and Lewis lung carcinoma cells. No biological function has yet been determined for tetran... | |||
T82379 |
FN-A208 fusion peptide
|
||
FN-A208 是源自鼠层粘连蛋白 a1 的 A208 与纤连蛋白 (GRGDS) 活性位点和甘氨酸间隔区融合形成的生物活性肽。该肽能形成淀粉样原纤维,并有助于促进肌动蛋白应力纤维的形成,进而介导成纤维细胞附着,显示出其在组织再生和工程生物粘合剂方面的应用潜力。FN-A208 与 IKVAV 受体和整合素发生相互作用,而在 EDTA 存在下,其活性则会被破坏。 | |||
T83770 |
Klotho-derived Peptide 1 (56-87) (human) TFA
KP1 (56-87) |
||
Klotho衍生肽1(KP1)(56-87)是从人类Klotho蛋白质中衍生的肽,具有扰乱TGF-β信号传导的作用。它与TGF-β受体类型1(TGFBR2)和TGF-β受体类型2(TGFBR2;Kds分别为1.41和14.6µM)结合。KP1(10 µg/ml)的预孵育抑制TGF-β在NRK-49F大鼠成纤维细胞中诱导的纤维连接蛋白和α-平滑肌肌动蛋白(α-SMA)水平的增加。在体内,KP1(每天1 mg/kg)选择性地定位于受损的肾脏,并减少血清肌酐和血尿素氮水平,这些是肾功能的标志物,同时也减少了小鼠单侧输尿管阻塞(UUO)和单侧缺血-再灌注损伤诱导的肾脏纤维化模型中的肾纤维化。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40960 |
Fibronectin
|
Integrin | Cytoskeletal Signaling |
Fibronectin 是存在于血液、结缔组织和细胞表面中的高分子糖蛋白,可作为组织损伤的生物标记物。Fibronectin 可被整合素家族表面受体识别。Fibronectin 可用于研究原发性开角型青光眼。 | |||
TN2165 |
Rubrofusarin gentiobioside
Rubrofusarin-6-O-beta-D-gentiobioside,红链霉素-龙胆二糖苷,芸苔红素龙胆苷 |
ERK; NF-κB; TGF-beta/Smad | MAPK; NF-κB; Stem Cells |
Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) 一种分离自决明子的、具有清除自由基作用的化合物。 | |||
T2S2043 |
Dracorhodin perchlorate
Dracorhodin perochlorate,血竭素高氯酸盐,Dracohodin perochlorate |
Apoptosis; Others | Apoptosis; Others |
Dracorhodin perchlorate 是来源于中药血竭的一种天然产物。它抑制细胞生长,并以剂量和时间依赖性方式诱导成纤维细胞凋亡,将细胞周期阻滞在 G1 期,可作为抗乳腺癌的候选药物。 | |||
T72798 |
Ganodermaones B
|
||
Ganodermaones B 是一种肾纤维化抑制剂,抑制 TGF-β1诱导的 collagen I 和 fibronectin 的表达。 | |||
T83392 |
2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid
|
||
2a,3a,23-Trihydroxyurs-12,20(30)-dien-28-oic acid(化合物3)是一类三萜类化合物,能显著抑制高糖和TGF-b1诱导的HK-2细胞内纤连蛋白水平,其10μM浓度下的抑制率达27.66%。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00803 |
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,... |
Human | HEK293 Cells |
Fibronectin Protein, Human, Recombinant (aa 607-1265, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.2 kDa and the accession number is P02751-15. | |||
TMPJ-01430 |
NovoNectin Protein, Human, Recombinant
NovoNectin,Cold-insoluble globulin,FN,CIG,Fibronectin |
Human | E. coli |
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a hepar... | |||
TMPJ-01433 |
Fibronectin Protein, Human, Recombinant (ED-B domain, Avi & His), Biotinylated
Fibronectin,FN1 |
Human | E. coli |
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins, fibronectin binds extracellular matrix components such as collagen, fibrin, and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion, growth, migration, and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, an... | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fib... |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-04643 |
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His)
integrin, α5 (fibronectin receptor, α polypeptide),... |
Mouse | HEK293 Cells |
Integrin alpha V beta 6 Protein, Mouse, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is NP_032428.2&NP_067334.1. | |||
TMPY-02159 |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His)
Integrin alpha 5 β1,Integrin α5 β 1,integrin, α5 (fibron... |
Human | HEK293 Cells |
Integrin alpha 5 beta 1 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 192 kDa and the accession number is P08648&P05556-1. | |||
TMPY-05562 |
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)
fibronectin 1,ED-B,CIG,FNZ,MSF,FN,FINC,GFND,LETS,GF... |
Human | HEK293 Cells |
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa and the accession number is P02751-15. | |||
TMPY-00476 |
ITGB1 Protein, Human, Recombinant (His)
VLAB,integrin, beta 1 (fibronectin receptor, beta p... |
Human | HEK293 Cells |
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe... | |||
TMPJ-01228 |
Irisin Protein, Human/Mouse/Rat, Recombinant (N-His)
Irisin,Fibronectin type III repeat-containing prote... |
Human,Mouse,Rat | HEK293 Cells |
Irisin Protein, Human/Mouse/Rat, Recombinant (N-His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18-28 KDa and the accession number is Q8NAU1. | |||
TMPJ-01227 |
Irisin Protein, Human/Mouse/Rat, Recombinant (C-His)
FNDC5,Fibronectin type III repeat-containing protei... |
Human,Mouse,Rat | HEK293 Cells |
Irisin Protein, Human/Mouse/Rat, Recombinant (C-His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-28 KDa and the accession number is Q8NAU1. | |||
TMPY-03578 |
FLRT2 Protein, Mouse, Recombinant (His)
FLRT2,fibronectin leucine rich transmembrane protei... |
Mouse | HEK293 Cells |
FLRT2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.6 kDa and the accession number is Q8BLU0. | |||
TMPH-01338 |
Fibronectin Protein, Human, Recombinant (His)
|
Human | E. coli |
Fibronectin Protein, Human, Recombinant (His) is expressed in E. coli expression system with His-tag tag. The predicted molecular weight is 23.6 kDa and the accession number is P02751. | |||
TMPJ-01226 |
Irisin Protein, Human/Mouse/Rat, Recombinant (hFc)
Irisin,FNDC5,Fibronectin type III repeat-containing... |
Human,Mouse,Rat | HEK293 Cells |
Irisin Protein, Human/Mouse/Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-60 KDa and the accession number is Q8NAU1. | |||
TMPY-02032 |
FLRT1 Protein, Human, Recombinant (His)
SPG68,fibronectin leucine rich transmembrane protei... |
Human | HEK293 Cells |
The three fibronectin leucine-rich repeat transmembrane (FLRT) proteins contain 10 leucine-rich repeats (LRR), a type III fibronectin (FN) domain, followed by the transmembrane region, and a short cytoplasmic tail. FLRT1 is expressed in kidney and brain, which is a target for tyrosine phosphorylation mediated by FGFR1 and implicates a non-receptor Src family kinase (SFK). All FLRTs can interact with FGFR1 and FLRTs can be induced by the activation of FGF signalling by FGF-2. The phosphorylation ... | |||
TMPY-01438 |
FLRT3 Protein, Human, Recombinant (His)
fibronectin leucine rich transmembrane protein 3,HH... |
Human | HEK293 Cells |
Leucine-rich repeat transmembrane protein FLRT3, also known as Fibronectin-like domain-containing leucine-rich transmembrane protein 3, and FLRT3, is a single-pass type I membrane protein which belongs to the fibronectin leucine rich transmembrane protein (FLRT) family. FLRT3 contains one fibronectin type-III domain and ten LRR (leucine-rich) repeats and is expressed in kidney, brain, pancreas, skeletal muscle, lung, liver, placenta, and heart. It has a provocative expression pattern during somi... | |||
TMPY-00176 |
FNDC4 Protein, Human, Recombinant (mFc)
fibronectin type III domain containing 4,FRCP1 |
Human | HEK293 Cells |
FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. FNDC4 could suppress osteoclast formation via NF-kappaB pathway and downregulation of CXCL10. Analysis of binding of FNDC4 to different immune cell types reveals strong and specific binding to macrophages and monocytes. FNDC4 treatment of bone marrow-derived macrophages in vitro results in reduced phagocytosis, increased cell survival and reduced proinflammatory chemokine expression. Hence, trea... | |||
TMPY-02048 |
FLRT2 Protein, Human, Recombinant (His)
UNQ232/PRO265,fibronectin leucine rich transmembran... |
Human | HEK293 Cells |
FLRT2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is O43155. | |||
TMPK-01390 |
Fibronectin Protein, Human, Recombinant (aa 32-602, His)
FNZ,ED-B,SMDCF,FN1,GFND,MSF,GFND2,LETS,FN,FINC,CIG |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 32-602, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted m... | |||
TMPK-01391 |
Fibronectin Protein, Human, Recombinant (aa 1266-1356, His)
FN1,LETS,GFND,MSF,FNZ,CIG,ED-B,FN,SMDCF,GFND2,FINC |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, His) is expressed in HEK293 mammalian cells with C-His tag. The predicte... | |||
TMPK-01389 |
Fibronectin Protein, Human, Recombinant (aa 32-345, His)
MSF,ED-B,LETS,SMDCF,FN,GFND2,CIG,FNZ,FN1,GFND,FINC |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 32-345, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted m... | |||
TMPK-01373 |
Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc)
FINC,LETS,GFND,SMDCF,GFND2,ED-B,MSF,FNZ,FN1,FN,CIG |
Human | HEK293 Cells |
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells to the surrounding extracellular matrix. Fibronectin has affinity to the other main components of extracellular matrix, collagen and glycosaminoglycans. Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicte... | |||
TMPH-03003 |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
Diacylglycerol acyltransferase/mycolyltransferase Ag85A,Acyl... |
Mycobacterium tuberculosis | E. coli |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.6 kDa and the accession number is P9WQP2. | |||
TMPJ-00786 |
ITGB1 Protein, Human, Recombinant (aa 21-728, His)
Integrin Beta-1,VLA-4 Subunit β,Fibronectin Recepto... |
Human | HEK293 Cells |
Integrin β-1 (ITGB1) belongs to the integrin β chain family. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. ITGB1 is an integrin unit associated with very late antigen receptors, which contains one VWFA domain. It is known to conjoin with α-3 subunit to create α3β1 complex that reacts to such molecules as netrin-1 and ree... | |||
TMPJ-00810 |
ITGA5 Protein, Human, Recombinant (His)
FNRA,Integrin α-5,Integrin Alpha-F,Fibronectin Rece... |
Human | HEK293 Cells |
Integrin α-5 belongs to the Integrin α chain family and contains 7 FG-GAP repeats. Integrin α-5 joins with Integrin-β1 to form a fibronectin and laminin receptor which recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. It is expressed on fibroblasts, endothelial cells, peripheral T cells and platelets. Integrin α-5 undergoes post-translational cleavage in the ext... | |||
TMPH-03004 |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His)
Diacylglycerol acyltransferase/mycolyltransferase Ag85A,... |
Mycobacterium tuberculosis | E. coli |
Ag85A Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.1 kDa and the accession number is P9WQP2. | |||
TMPH-03007 |
Ag85C Protein, Mycobacterium tuberculosis, Recombinant (His)
Acyl-CoA:diacylglycerol acyltransferase,Fibronectin... |
Mycobacterium tuberculosis | E. coli |
Ag85C Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.1 kDa and the accession number is P9WQN8. | |||
TMPH-03005 |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His)
30 kDa extracellular protein,DGAT,Fbps B,Diacylglycerol acyl... |
Mycobacterium tuberculosis | E. coli |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 36.2 kDa and the accession number is P9WQP0. | |||
TMPH-03006 |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His)
30 kDa extracellular protein,Diacylglycerol acyltransferase/... |
Mycobacterium tuberculosis | P. pastoris (Yeast) |
Ag85B Protein, Mycobacterium tuberculosis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.7 kDa and the accession number is P9WQP0. | |||
TMPJ-00194 |
IL-20RB Protein, Human, Recombinant (hFc)
DIRS1,IL-20R-β,Interleukin-20 receptor subunit β,IL-20 recep... |
Human | HEK293 Cells |
Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do no... | |||
TMPY-05716 |
Integrin alpha V beta 3 Protein, Human, Recombinant (His)
Integrin α V β 3,Integrin alpha V β3 |
Human | HEK293 Cells |
Integrin alpha-V & beta-3 (ITGAV/ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. | |||
TMPK-01393 |
Tenascin Protein, Mouse, Recombinant (His)
Hexabrachion,Hxb,TN-C,TN,TNC,Tenascin-C |
Mouse | HEK293 Cells |
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... | |||
TMPK-01392 |
Tenascin Protein, Human, Recombinant (His)
Tenascin-C,TNC,TN,Hexabrachion,Hxb,TN-C |
Human | HEK293 Cells |
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tena... | |||
TMPY-05717 |
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
Integrin alpha V β8,Integrin α V β 8 |
Human | HEK293 Cells |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cytoskeleton. It binds ligands containing an RGD motif; including vitronectin; fibrin and the latency associated peptide (LAP) of the latent TGF-beta complex. High affinity binding of alpha V beta 8 to LAP allows proteolytic cleavage by MT1-MMP; which releases active TGF-beta. This m... | |||
TMPJ-01204 |
TPSAB1 Protein, Human, Recombinant (His)
TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1... |
Human | HEK293 Cells |
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s... | |||
TMPY-00021 |
PADI4 Protein, Human, Recombinant (His)
PADI5,PAD4,PDI4,peptidyl arginine deiminase, type IV,PAD,PDI... |
Human | Baculovirus Insect Cells |
Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase family. PADI4 is expressed in CD34+stem cells in normal tissues, and many more CD34+ cells expressing PADI4 are present in tumour tissues. PADI4 post-translationally converts peptidylarginine to citrulline, a process called citrullination. Studies have demonstrated the high expres... | |||
TMPH-02145 |
MMP-3 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. | |||
TMPH-03019 |
MPT51 Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
|
Mycobacterium tuberculosis | E. coli |
May have a role in host tissue attachment, whereby ligands may include the serum protein fibronectin and small sugars. MPT51 Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.5 kDa and the accession number is P9WQN6. | |||
TMPH-01644 |
MMP-7 Protein, Human, Recombinant (GST)
|
Human | E. coli |
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. MMP-7 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 46.1 kDa and the accession number is P09237. | |||
TMPH-03331 |
MMP-7 Protein, Rat, Recombinant (GST)
|
Rat | E. coli |
Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase. MMP-7 Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 45.9 kDa and the accession number is P50280. | |||
TMPJ-01443 |
HChFc2 Protein, Mouse, Recombinant (His)
C2 factor,HCF-2,Host cell factor 2,Hcfc2 |
Mouse | E. coli |
Host cell factor 2(HCFC2) is a cytoplasmic protein. It contains 2 fibronectin type-III domains.HCFC2 binds KMT2A/MLL1, as component of the MLL1/MLL complex.Hcfc2 negative regulation of transcription from RNA polymerase II promoter. | |||
TMPH-00217 |
SVMP Protein, Bothrops leucurus, Recombinant (His & Myc)
|
Bothrops leucurus | E. coli |
Non-hemorrhagic metalloproteinase that hydrolyzes the alpha chains of fibrinogen, as well as fibrin, fibronectin and casein. Beta and gamma chains are also hydrolyzed, but more slowly. Thrombolytic activity is also observed. Induces detachment of endothelial cells followed by death, and inhibits endothelial cell adhesion to fibronectin. Induces edema in mouse paw. Inhibits ADP-induced platelet aggregation on human platelet-rich plasma with an IC(50) of 2.8 uM. SVMP Protein, Bothrops leucurus, Re... | |||
TMPH-02915 |
MMP-3 Protein, Mouse, Recombinant (His)
|
Mouse | E. coli |
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. MMP-3 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.2 kDa and the accession number is P28862. | |||
TMPH-02146 |
MMP-10 Protein, Human, Recombinant (His)
|
Human | E. coli |
Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase. MMP-10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 47.0 kDa and the accession number is P09238. | |||
TMPK-00994 |
FNDC1 Protein, Human, Recombinant (His)
FNDC2,MEL4B3,KIAA1866 |
Human | E. coli |
Fibronectin type III domain‑containing protein 1 (FNDC1) is a protein that contains a major component of the structural domain of fibronectin.FNDC1 was highly upregulated and acted as an oncogene in BC. Therefore, targeting FNDC1 may be a potential strategy for the treatment of BC. | |||
TMPH-00671 |
Major curlin subunit Protein, E. coli O157:H7, Recombinant (His)
|
E. coli | P. pastoris (Yeast) |
Curlin is the structural subunit of the curli. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli can bind to fibronectin. Major curlin subunit Protein, E. coli O157:H7, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 14.6 kDa and the accession number is Q93U24. | |||
TMPH-02934 |
Thrombospondin-3/THBS3 Protein, Mouse, Recombinant (GST)
|
Mouse | E. coli |
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Can bind to fibrinogen, fibronectin, laminin and type V collagen. Thrombospondin-3/THBS3 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 62.7 kDa and the accession number is Q05895. | |||
TMPJ-01269 |
BOC Protein, Human, Recombinant (His)
Brother of CDO,Boc homolog (Mouse),BOC protein,isoform CRA_b |
Human | HEK293 Cells |
Brother of CDO is a protein that in humans is encoded by the BOC gene. CDON and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail. | |||
TMPJ-00407 |
ROBO4 Protein, Human, Recombinant (hFc)
Magic roundabout,Roundabout homolog 4,UNQ421/PRO3674,ROBO4 |
Human | HEK293 Cells |
Roundabout homolog 4(ROBO4) contains 2 fibronectin type-III domains, 2 Ig-like C2-type (immunoglobulin-like) domains and belongs to the immunoglobulin superfamily.The protein is a receptor for slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. ROBO4 may mediate the inhibition of primary endothelial cell migration by Slit proteins. | |||
TMPJ-00119 |
IL-22RA2 Protein, Human, Recombinant (hFc)
Cytokine Receptor Family 2 Member 10,CRF2-10,IL-22RA2,Interl... |
Human | HEK293 Cells |
Interleukin-22 Receptor Subunit α-2 (IL22RA2) belongs to the type II cytokine receptor family. IL22RA2 is a secreted protein and contains three fibronectin type-III domains. IL22RA2 is widely expressed in many tissues. IL22RA2 functions as an IL22 antagonist and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. | |||
TMPK-00574 |
MRC2 Protein, Canine, Recombinant (His)
Mannose receptor C type 2 |
Canine | HEK293 Cells |
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.76 kDa and ... | |||
------------------------ 更多 ------------------------ |