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Search Results for " estradiol "

43

抑制剂 & 化合物

12

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T40580	17β-Estradiol sulfate sodium 17β-Estradiol 3-sulfate sodium	Antibiotic	Microbiology/Virology
	17β-Estradiol sulfate sodium (17β-Estradiol 3-sulfate sodium) 是一种神经活性雌激素，具有血管保护作用，可抑制巴西奈瑟菌的生长，破环水生生态系统。
T0168	Estradiol (cypionate) Depofemin,环戊丙酸雌二醇,Estradiol cypionate	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Estradiol cypionate (Depofemin) 是一种 Estradiol 的 17β-环戊丙酸酯，能够作用于雌激素受体。抑制ET-1的合成。
T2231	Estradiol dipropionate 17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Progesterone Receptor	Endocrinology/Hormones; Others
	Estradiol dipropionate (17-Beta-Estradiol-3,17-Dipropionate) 是雌激素-孕激素的组合物，可用作雌激素 (estrogen) 孕激素 (progesterone) 激动剂。
T0384	Estradiol benzoate Benzoestrofol,Benzhormovarine,苯甲酸雌二醇,Benovocylin	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Estradiol benzoate (Benzhormovarine) 是一种类固醇性激素，是一种雌二醇的前体药物。它表现出轻微的合成代谢特性，增加血液凝固性。
T9604	beta-Estradiol 17-hemisuccinate	Estrogen Receptor/ERR	Endocrinology/Hormones
	beta-Estradiol 17-hemisuccinate 选择性染色富含雌激素受体 (ER) 的细胞。
T11235	Estradiol 3-sulfamate 雌二醇 3-氨基磺酸,ES-J 995,E2MATE,BLE 00084	Others	Others
	.Estradiol 3-sulfamate inhibits estrone sulfatase with an IC50 of 251 nM and a Ki of 133 nM. Estradiol 3-sulfamate is a potent, long-acting, and orally active steroid sulfatase inhibitor.
T72390	Estradiol hemihydrate 17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate
	Estradiol (β-Estradiol) hemihydrate 是主要女性性激素的类固醇激素。它能上调人类子宫内膜干细胞 (hEnSCs) 的神经标志物表达，促进神经分化，适用于癌症、神经退行性疾病和神经组织工程研究。
T1536	Promestriene 3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano	Estrogen/progestogen Receptor	Endocrinology/Hormones
	Promestriene (3-propyl ethyl) 是局部有效的雌激素，是合成的雌二醇二乙醚。它对阴道萎缩有作用，但吸收量小。
T31681	Estradiol undecylate AI352642,AI3-52642,AI3 52642
	Estradiol undecylate can be used in the treatment of prostatic cancer.
T37004	Estradiol 3-sulfate 17β-Glucuronide (potassium salt)
	Estradiol 3-sulfate is a sulfated form of the steroid hormone 17β-estradiol , and is common in fetal plasma and in the breast tissues of patients with mammary carcinoma. Sulfated estrogens, including estradiol 3-sulfate, can be converted back to the parent compound by sulfatases. Estradiol 3-sulfate 17β-glucuronide is a metabolite of estradiol 3-sulfate that has been modified by a UDP-glucuronosyltransferase. Glucuronidation of estrogens enhances their utilization by anion transporters, most com...
T36917	Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)
	Ethynyl estradiol 3-β-D-glucuronide is a metabolite of ethynyl estradiol that can be detected in urine.1,2It is used as a marker of estrogen contamination in fresh and saltwater.2 1.Hadd, H.E., Slikker, W., Jr., and Helton, E.D.The synthesis and characterization of the glucopyranosiduronic acids of 17a-ethynylestradiol-17bJ. Steroid Biochem.13(9)1107-1114(1980) 2.Griffith, D.R., Soule, M.C.K., Eglinton, T.I., et al.Steroidal estrogen sources in a sewage-impacted coastal oceanEnviron. Sci.: Proce...
T36807	Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
	Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...
T18876	β-Estradiol-6-CMO-PEG3-biotin	Others	Others
	β-Estradiol-6-CMO-PEG3-biotin serves as a cleavable 3-unit PEG ADC linker for the synthesis of antibody-drug conjugates (ADCs)[1].
T18877	β-Estradiol-6-one 6-(O-carboxymethyloxime)	Others	Others
	β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker utilized for PROTAC synthesis[1].
T65147	Estradiol enanthate
	Estradiol enanthate 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65147，CAS号为 4956-37-0。
T1579	Mestranol Devocin,Norquen,美雌醇,Menophase	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Mestranol (Devocin) 是一种雌激素受体激动剂，是一种非活性的前药，在转化为炔雌醇时具有生物活性。动物实验中，它可以与黄体酮联合使用，它可用于更年期激素或月经紊乱的研究。
T2569	Chlorotrianisene tris(p-methoxyphenyl)chloroethylene,氯丁烯二烯,CTA,tri-p-anisylchloroethylene,氯烯雌醚,TACE	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; COX	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Chlorotrianisene (tri-p-anisylchloroethylene) 是长效、可口服、亲脂性高的合成三苯乙烯 (TPE) 衍生物和选择性雌激素受体调节剂，有雌激素活性，也有抗雌激素活性。它还有效抑制COX-1并抑制全血中的血小板聚集。
T31699	Ethinylestradiol mixture with Levonorgestrel
	Ethinylestradiol mixture with Levonorgestrel is formulated with increasing dosages of levonorgestrel and ethinyl estradiol.
T31578	Drospirenone mixture with Ethinylestradiol Yaz 28,Nikki,Ocella,Yaz-28,Yasmin 28,Syeda
	Drospirenone mixture with Ethinylestradiol is a female oral combined contraceptive containing 30 mcg (0.030 mg) Ethinyl Estradiol and 3 mg drospirenone (Androstenes).
T31715	Ethynylestradiol mixture with lynestrenol
	Ethynylestradiol mixture with lynestrenol is a drug/ therapeutic agent with reproductive effect.
T24973	2-Iodoestradiol 2 Iodoestradiol,NSC671618,NSC 671618,NSC-671618
	2-Iodoestradiol is an effective human sex hormone-binding globulin (SHBG) ligand.
T131627	Oestradiol
	Oestradiol 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131627。
T14577	Biotin-DADOO EZ-Link Amine-PEO2-Biotin,Biotinyl-3,6-dioxaoctanediamine	Others	Others
	Biotin-DADOO (Biotinyl-3,6-dioxaoctanediamine) 是生物素酰化试剂，能够与雌二醇结合，形成生物素-雌二醇共轭化合物，进而利用酶免疫测定法测定血浆雌二醇的浓度。
T7537	Norgestimate 炔诺肟酯,诺孕酯	Progesterone Receptor	Others
	Norgestimate 是一种具有口服活性、高度选择性的孕激素活性和较小雄激素作用的孕激素，是一种合成的孕激素类似物。它可用作口服的避孕药。
T10239	Acolbifene 阿考比芬,EM-652,SCH 57068	Estrogen Receptor/ERR	Endocrinology/Hormones
	Acolbifene (SCH 57068) 是一种选择性雌激素受体拮抗剂，对雌二醇诱导的 ERα 和 ERβ 转录活性的 IC50 分别为 2 nM 和 0.4 nM。 Acolbifene 显示出抗癌特性。
T11399	Giredestrant GDC-9545	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Giredestrant (GDC-9545) 是一种口服有效的、选择性的、非甾体的雌激素受体 (ER) 拮抗剂，具有抗肿瘤作用。它可以在 ER 配体结合域内与雌二醇 (Estradiol) 竞争结合并诱导构象变化。
T25048	Algestone acetophenide Neolutin,苯甲孕酮	Others	Others
	Algestone acetophenide (Neolutin) 是用于发情同步的孕酮，已被评估为与庚酸雌二醇联合使用的注射避孕药。它在治疗上也用作局部抗炎药，并在治疗痤疮时局部应用。
T20681	Estramustine NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275	Microtubule Associated	Cytoskeletal Signaling
	Estramustine (LEO-275) 是一种与雌二醇相连的氮芥，通常为磷酸盐。它已被用于治疗前列腺肿瘤；还具有防辐射功能。它被前列腺细胞选择性吸收，并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。
T22794	G36 G-36	Estrogen Receptor/ERR	Endocrinology/Hormones
	G36是一种细胞可渗透的G 蛋白偶联雌激素受体(GPER/GPR30)的非甾体拮抗剂。G36抑制17β-雌二醇或GPER 选择性激动剂G-1的激活（IC50分别为112和165 nM）。G36对ERα或ERβ均无可检测的结合活性。G36通过GPER 阻断由雌激素触发的PI3K 的激活或钙动员，并且它通过雌激素或G-1而不是通过EGF 抑制ERK 的激活。
T25390	Estrandron
	Estrandron is an agent containing testosterone, estradiol or their derivatives reported in eastern European literature.
T26154	RU 45144 RU45144,RU-45144
	RU 45144 is an estradiol derivative with antiestrogenic activity.
T14344	Atrimustine 阿莫司汀,KM2210,Bestrabucil	Others	Others
	Atrimustine is a conjugate of chlorambucil and β-estradiol benzoate. It has the antitumor activity.
T10036	10β,17β-dihydroxyestra-1,4-dien-3-one DHED	Others	Others
	10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
TP2010	Kisspeptin 10 (dog)
	Endogenous ligand for the canine KISS1 receptor (Kisspeptin receptor or GPR54). Stimulates section of luteinizing hormone, follicle stimulating hormone and estradiol in vivo.
T36916	Estrone-3-Glucuronide (sodium salt hydrate)
	Estrone-3-Glucuronide is a metabolite of the primary premenopausal estrogen 17β-estradiol .1,2Urinary levels of estrone-3-Glucuronide peak approximately 36 hours prior to ovulation and have been used as a marker of fertility in women. 1.Blackwell, L.F., Brown, J.B., and Cooke, D.Definition of the potentially fertile period from urinary steroid excretion rates. Part II. A threshold value for pregnanediol glucuronide as a marker for the end of the potentially fertile period in the human menstrual ...
T73765	Estrone 3-glucuronide
	Estrone 3-glucuronide是Estrone 3-glucuronide的氘代物，作为雌二醇的主要代谢产物，是预测可育期的重要泌尿标记物。
T70399	TTC-352
	TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells.
T36913	17-Epiestriol
	17-Epiestriol is a metabolite of estrone .1It is formed from estroneviaa 16α-hydroxy estrone intermediate by reduction of the C-17 ketone. 17-Epiestriol binds to estrogen receptor α (ERα) and ERβ with relative binding affinities of 29 and 80 compared with 17β-estradiol .2 1.Brinton, L.A., Trabert, B., Anderson, G.L., et al.Serum estrogens and estrogen metabolites and endometrial cancer risk among postmenopausal womenCancer Epidemiol. Biomarkers Prev.25(7)1081-1089(2016) 2.Kuiper, G.G.J.M., Lemme...
T76222	hFSH-β-(33-53) (TFA)
	hFSH-β-(33-53) TFA 是一种含有硫醇的肽，对应于第二个 FSH 受体结合域，是 FSHR(卵泡刺激素受体) 拮抗剂。hFSH-β-(33-53) TFA 抑制 FSH 与受体的结合，是 Sertoli 细胞中雌二醇合成的部分激动剂。
T74335	PSDalpha
	PSDalpha 是一种ERα降解剂，通过乙炔键结合光敏剂 (PS)、三苯胺苯并噻二唑 (TB) 和 17β-雌二醇。PSDalpha 对 MCF-7 细胞表现出优异的抗增殖性能。PSDalpha 在可见光区的 λmax 位于 465 nm。
T60827	TPBM
	TPBM 是雌激素受体 α (ERα)的有效抑制剂。TPBM 对 17β-雌二醇 (E2)-ERα 的IC50值为 9 μM。TPBM 对细胞无毒，可减少 E2·ERα 向内源性雌激素反应基因的募集。TPBM 抑制 ERα 阳性癌细胞的 E2 依赖性生长，IC 50 值为 5 μM。 TPBM 不影响非雌激素依赖性细胞生长。
T36039	16α-Hydroxyestrone
	The naturally-occurring estrogens are estrone , estradiol , and estriol . 16α-hydroxy Estrone (16α-OHE1) is a hydroxylated metabolite of E1 as well as an interconversion product with E2. E1 is 16α-hydroxylated by cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A5, CYP3A4, and CYP3A7, with CYP3A5 being breast-specific. 16α-OHE1 is sulphatized or glucuronidated before excretion. It is increased in rheumatoid arthritis and decreased by physical activity. Unlike the parent estrogens and other ...
T70309	Dicetrorelix pamoate
	Dicetrorelix pamoate is a synthetic decapeptide with gonadotropin-releasing hormone (GnRH) antagonistic activity. GnRH induces the production and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH) from the gonadotrophic cells of the anterior pituitary. Due to a positive estradiol (E2) feedback at midcycle, GnRH liberation is enhanced resulting in an LH-surge. This LH-surge induces the ovulation of the dominant follicle, resumption of oocyte meiosis and subsequently lutein...

化合物

17β-Estradiol sulfate sodium

Cat.No: T40580

Synonym: 17β-Estradiol 3-sulfate sodium

Target: Antibiotic

Estradiol (cypionate)

Cat.No: T0168

Synonym: Depofemin,环戊丙酸雌二醇,Estradiol cypionate

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Estradiol dipropionate

Cat.No: T2231

Synonym: 17-Beta-Estradiol-3,17-Dipropionate,3,17-二丙酸-17-BETA-雌二酯,二丙酸雌二醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Progesterone Receptor

Estradiol benzoate

Cat.No: T0384

Synonym: Benzoestrofol,Benzhormovarine,苯甲酸雌二醇,Benovocylin

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

beta-Estradiol 17-hemisuccinate

Cat.No: T9604

Target: Estrogen Receptor/ERR

Estradiol 3-sulfamate

Cat.No: T11235

Synonym: 雌二醇 3-氨基磺酸,ES-J 995,E2MATE,BLE 00084

Target: Others

Estradiol hemihydrate

Cat.No: T72390

Synonym: 17β-Oestradiol hemihydrate,β-Estradiol hemihydrate ; 17β-Estradiol hemihydrate ; 17β-Oestradiol hemihydrate,17β-Estradiol hemihydrate,β-Estradiol hemihydrate

Cat.No: T1536

Synonym: 3-propyl ethyl,舒经劳,17B-methyl estradiol,Promestriano

Target: Estrogen/progestogen Receptor

Estradiol undecylate

Cat.No: T31681

Synonym: AI352642,AI3-52642,AI3 52642

Estradiol 3-sulfate 17β-Glucuronide (potassium salt)

Cat.No: T37004

Ethynyl Estradiol 3-β-D-Glucuronide (hydrate)

Cat.No: T36917

Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Cat.No: T36807

β-Estradiol-6-CMO-PEG3-biotin

Cat.No: T18876

Target: Others

β-Estradiol-6-one 6-(O-carboxymethyloxime)

Cat.No: T18877

Target: Others

Estradiol enanthate

Cat.No: T65147

Cat.No: T1579

Synonym: Devocin,Norquen,美雌醇,Menophase

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Chlorotrianisene

Cat.No: T2569

Synonym: tris(p-methoxyphenyl)chloroethylene,氯丁烯二烯,CTA,tri-p-anisylchloroethylene,氯烯雌醚,TACE

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, COX

Ethinylestradiol mixture with Levonorgestrel

Cat.No: T31699

Drospirenone mixture with Ethinylestradiol

Cat.No: T31578

Synonym: Yaz 28,Nikki,Ocella,Yaz-28,Yasmin 28,Syeda

Ethynylestradiol mixture with lynestrenol

Cat.No: T31715

2-Iodoestradiol

Cat.No: T24973

Synonym: 2 Iodoestradiol,NSC671618,NSC 671618,NSC-671618

Cat.No: T131627

Cat.No: T14577

Synonym: EZ-Link Amine-PEO2-Biotin,Biotinyl-3,6-dioxaoctanediamine

Target: Others

Cat.No: T7537

Synonym: 炔诺肟酯,诺孕酯

Target: Progesterone Receptor

Cat.No: T10239

Synonym: 阿考比芬,EM-652,SCH 57068

Target: Estrogen Receptor/ERR

Cat.No: T11399

Synonym: GDC-9545

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Algestone acetophenide

Cat.No: T25048

Synonym: Neolutin,苯甲孕酮

Target: Others

Cat.No: T20681

Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275

Target: Microtubule Associated

Cat.No: T22794

Synonym: G-36

Target: Estrogen Receptor/ERR

Cat.No: T25390

Cat.No: T26154

Synonym: RU45144,RU-45144

Cat.No: T14344

Synonym: 阿莫司汀,KM2210,Bestrabucil

Target: Others

10β,17β-dihydroxyestra-1,4-dien-3-one

Cat.No: T10036

Synonym: DHED

Target: Others

Kisspeptin 10 (dog)

Cat.No: TP2010

Estrone-3-Glucuronide (sodium salt hydrate)

Cat.No: T36916

Estrone 3-glucuronide

Cat.No: T73765

Cat.No: T70399

Cat.No: T36913

hFSH-β-(33-53) (TFA)

Cat.No: T76222

Cat.No: T74335

Cat.No: T60827

16α-Hydroxyestrone

Cat.No: T36039

Dicetrorelix pamoate

Cat.No: T70309

Cat. No.	Product Name	Target	Signaling Pathways
T1048	Estradiol 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estradiol (E2) 是一种天然的类固醇性激素，对于女性生育能力和第二性征的维持至关重要。Estradiol 通过雌激素受体 β (ERβ) 上调 IL-6 表达。
T3378	Alpha-Estradiol α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol	Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Alpha-Estradiol (Epiestradiol) 是一种雌性激素，可抑制5α-reductase，在雄原性脱发的研究中有潜力。
T1424	Ethynyl estradiol 乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Ethynyl estradio 是一种高效的生物活性雌激素。
T7299	β-Estradiol 17-acetate β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate	Estrogen Receptor/ERR; Others	Endocrinology/Hormones; Others
	β-Estradiol 17-acetate (1,3,5(10)-Estratriene-3,17β-diol 17-acetate) 是一种雌二醇代谢物。
T9456	4-Methoxy 17β-Estradiol	Others	Others
	4-Methoxy 17β-Estradiol 是雌激素代谢物之一，也是 4-羟基雌二醇的甲基化代谢物。
T2220	2-Methoxyestradiol 2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2	Apoptosis; Reactive Oxygen Species; Microtubule Associated; Endogenous Metabolite; HIF; Autophagy	Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
	2-Methoxyestradiol (2-ME2) 是一种口服生物可利用的雌二醇代谢物，具有抗肿瘤活性。它通过减少内皮细胞增殖和诱导内皮细胞凋亡来抑制血管生成，也可破坏微管的稳定。它可诱导半胱天冬酶活化，导致细胞周期停滞在 G2 期、DNA 断裂和细胞凋亡。
T13481	2-Methoxyestrone	Endogenous Metabolite	Metabolism
	2-Methoxyestrone 是甲氧基苯二酚雌激素，也是雌酮代谢物，其 pKa=10.81。
TJS0856	Dalbergin 黄檀素,6-Hydroxy-7-Methoxy-4-Phenylcoumarin	Others	Others
	Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) 是一种 Dalbergia Sissoo Linn. knot wood 提取物的成分。它具有强大的抗氧化活性。
T16338	Norgestimate metabolite Norelgestromin 17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮	Drug Metabolite	Metabolism
	Norgestimate metabolite Norelgestromin (17-Deacylnorgestimate) 是norgestimate 的一种活性代谢物。它是用于避孕贴片的甾体孕激素，与雌激素乙炔雌二醇结合使用。
T1571	Estriol NSC-12169,Oestriol,雌三醇	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite	Endocrinology/Hormones; Immunology/Inflammation; Metabolism
	Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂，能够作用于雌激素受体阴性乳腺癌细胞。
T1009	Estrone Oestrone,雌酮,Fluoroethyl,Aquacrine	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Estrone (Aquacrine) 是内源性雌激素的主要代表，由多种组织产生，尤其是脂肪组织。它是脂肪细胞中雄烯二酮芳构化过程的结果。
T37452	Stephacidin B
	Stephacidin B is a fungal metabolite that has been found inA. ochraceus.1Dimeric stephacidin B is rapidly converted to a monomer, avrainvillamide ,in vitro.2Stephacidin B is cytotoxic to a variety of cancer cells, including testosterone-independent PC3 and -sensitive LNCaP prostate cancer cells (IC50s = 0.37 and 0.06 μM, respectively) and estradiol-independent SK-BR-3 and -sensitive MCF-7 breast cancer cells (IC50s = 0.32 and 0.27 μM, respectively).1It induces apoptosis in HepG2 and Huh7 hepatoc...

天然产物

Cat.No: T1048

Synonym: 雌二醇,E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Alpha-Estradiol

Cat.No: T3378

Synonym: α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol

Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite

Ethynyl estradiol

Cat.No: T1424

Synonym: 乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

β-Estradiol 17-acetate

Cat.No: T7299

Synonym: β-雌二醇 17-乙酸酯,17-乙酸-17-BETA-雌二酯,beta-estradiol 17-acetate,1,3,5(10)-Estratriene-3,17β-diol 17-acetate

Target: Estrogen Receptor/ERR, Others

4-Methoxy 17β-Estradiol

Cat.No: T9456

Target: Others

2-Methoxyestradiol

Cat.No: T2220

Synonym: 2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2

Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy

2-Methoxyestrone

Cat.No: T13481

Target: Endogenous Metabolite

Cat.No: TJS0856

Synonym: 黄檀素,6-Hydroxy-7-Methoxy-4-Phenylcoumarin

Target: Others

Norgestimate metabolite Norelgestromin

Cat.No: T16338

Synonym: 17-Deacetyl norgestimate,17-Deacylnorgestimate,甲基孕酮

Target: Drug Metabolite

Cat.No: T1571

Synonym: NSC-12169,Oestriol,雌三醇

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite

Cat.No: T1009

Synonym: Oestrone,雌酮,Fluoroethyl,Aquacrine

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Cat.No: T37452

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