Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Estradiol benzoate (Benzhormovarine) 是一种类固醇性激素,是一种雌二醇的前体药物。它表现出轻微的合成代谢特性,增加血液凝固性。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
500 mg | ¥ 331 | 现货 | ||
1 g | ¥ 415 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 415 | 现货 |
产品描述 | Estradiol benzoate (Benzhormovarine) is the synthetic benzoate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. |
靶点活性 | mERα:2.3 nM, hERα:28 nM |
体外活性 | Estradiol benzoate is asynthetic ester, specifically the 3-benzoyl ester, of the natural estrogen, estradiol. Estrogens direct the development of the female genotype in embryogenesis and at puberty. Estradiol is the major estrogen secreted by the premenopausal ovary. Estradiol benzoate is an estradiol analog which contains a benzyl ester at the C-3 position and is often used in combination with a progestin to induce estrus in domestic livestock. This compound binds to the human and murine estrogen receptor α (ERα), and chicken ER with IC50 values in the range of 22-28 nM. This reflects a 6-10 fold reduction in binding affinity compared to estradiol. [1] |
别名 | Benzoestrofol, Benzhormovarine, 苯甲酸雌二醇, Benovocylin |
分子量 | 376.49 |
分子式 | C25H28O3 |
CAS No. | 50-50-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 70 mg/mL (185.9 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.6561 mL | 13.2806 mL | 26.5611 mL | 66.4028 mL |
5 mM | 0.5312 mL | 2.6561 mL | 5.3122 mL | 13.2806 mL | |
10 mM | 0.2656 mL | 1.3281 mL | 2.6561 mL | 6.6403 mL | |
20 mM | 0.1328 mL | 0.664 mL | 1.3281 mL | 3.3201 mL | |
50 mM | 0.0531 mL | 0.2656 mL | 0.5312 mL | 1.3281 mL | |
100 mM | 0.0266 mL | 0.1328 mL | 0.2656 mL | 0.664 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Estradiol benzoate 50-50-0 Endocrinology/Hormones Estrogen/progestogen Receptor Estrogen Receptor/ERR Benzoestrofol Benzhormovarine inhibit Estradiol Benzoate 苯甲酸雌二醇 Inhibitor Benovocylin Estradiol inhibitor