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Search Results for " elastase "

Targets Recommended: Others

78

抑制剂 & 化合物

17

天然产物

25

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T40495	Elastase from porcine pancreas 弹性蛋白酶,EC 3.2.1.35	Others	Others
	Elastase from porcine pancreas 由 240 个氨基酸残基组成，是一种丝氨酸蛋白酶，可以水解蛋白质和多肽。它可诱发仓鼠气肿。
T78633	MeOSuc-AAPV-CMK Elastase Inhibitor III
	MeOSuc-AAPV-CMK (Elastase Inhibitor III) 为一种特定抗体，不仅抑制白细胞弹性蛋白酶，也能够抑制组织蛋白酶 G 及蛋白酶 3。此外，MeOSuc-AAPV-CMK 可有效阻断白细胞弹性蛋白酶对脂联素进行裂解的作用。
T60855	Elastase-IN-1
	Elastase-IN-1 (Compound Q11) 是无毒的弹性蛋白酶抑制剂，IC50值为 0.897 μM。
T82483	Elastase LasB-IN-1
	ElastaseLasB-IN-1 (Compound 4b) 是一种选择性弹性蛋白酶LasB抑制剂，展现出抗菌活性，其IC50值为76 nM。
T79397	Neutrophil elastase inhibitor 4
	Neutrophilelastase inhibitor4 (compound 4f) 是竞争性抑制HNE的化合物，具有较低的半抑制浓度(IC50: 42.30 nM)和解离常数(Ki: 8.04 nM)。此外，该化合物能够诱导T47D细胞的apoptosis，并在多种细胞系中展现出抗增殖作用，分别在T47D、RPMI 8226、A549、HSF细胞系的IC50值为21.25、34.17、29.93、99.11 nM。
T74243	Tyrosinase/elastase-IN-1
	Tyrosinase/elastase-IN-1，一种来源于悬钩子叶的三萜类化合物，具有抑制酪氨酸酶和弹性蛋白酶活性的功能。
T12613L	BAY-85-8501	Serine Protease	Proteases/Proteasome
	BAY-85-8501 是选择性的人类中性脂酶抑制剂，IC50=65 pM。
T9964	BOS-318	Others	Others
	BOS-318是一种Furin 抑制剂，具有缓慢解离，高选择性，细胞通透性等特点。
T3107	Alvelestat AZD9668,Avelestat	Others; Serine Protease	Others; Proteases/Proteasome
	Alvelestat (AZD9668) 是一种口服活性，亲和性和选择性的中性粒细胞弹性蛋白酶 (NE) 抑制剂，pIC50=7.9 nM，Ki=为 9.4 nM，Kd=9.5 nM。
TP1012	CH 5450 Z-Ile-Glu-Pro-Phe-Ome	Others	Others
	CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) 是一种人心脏糜酶 chymase 的短肽类抑制剂。
T6986	Sivelestat ONO5046,EI546,西维来司他,LY544349	Others; SARS-CoV; Serine Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Sivelestat (ONO5046) 是一种选择性的中性粒细胞弹性蛋白酶抑制剂，其 IC50值为 44 nM，Ki 值为 200 nM。它有潜力研究 COVID-19 的急性肺损伤、急性呼吸窘迫综合征或弥散性血管内凝血。
T13389	ZD-0892	PI3K	PI3K/Akt/mTOR signaling
	ZD-0892 is a selective and poten neutrophil elastaset inhibitor(human neutrophil elastase and porcine pancreatic elastase with Kis of 6.7 and 200 nM, respectively).
T20163	Acetyltrialanine
	Acetyltrialanine 是一种二肽化合物，在 Tb+3-胰腺弹性蛋白酶复合物上的两个位点结合，可做为氮源使用。
T8563	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one	Serine Protease	Proteases/Proteasome
	2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one 是一种人类中性粒细胞弹性蛋白酶抑制剂。
T68099	midesteine MR-889	Others	Others
	Midesteine (MR-889) 是一种可逆、慢结合、完全竞争的蛋白酶抑制剂。
T8602	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE	Serine Protease	Proteases/Proteasome
	2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA6-BENZO[D]ISOTHIAZOL-3-ONE 靶向中性粒细胞弹性蛋白酶（人）。
T8677	3,4 Dichloroisocoumarin	Others; Serine Protease; Cysteine Protease	Others; Proteases/Proteasome
	3,4 Dichloroisocoumarin 是一种颗粒酶、组织蛋白酶 G 和中性粒细胞弹性蛋白酶抑制剂
T38364	MeOSuc-AAPV-AMC MeOSuc-Ala-Ala-Pro-Val-AMC
	MeOSuc-AAPV-AMC (MeOSuc-Ala-Ala-Pro-Val-AMC)是人类白细胞和猪胰腺弹性蛋白酶的荧光底物，是一种四肽。
T10473	BAY-678	Others	Others
	BAY-678是一种人中性粒细胞弹性蛋白酶（HNE；IC50：20 nM）抑制剂，具有口服生物活性、高效性和选择性。BAY-678 是被基因结构组学联盟 (SGC) 推荐的化学探针。
T20762	Sivelestat sodium tetrahydrate ONO-5046 sodium tetrahydrate,Elaspol,ONO 5046,ONO5046 sodium tetrahydrate,Elaspol sodium tetrahydrate,ONO-5046,Sivelestat Sodium,Sivelestat Sodium Hydrate,ONO5046	Serine Protease	Proteases/Proteasome
	Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) 是竞争性的人类中性粒细胞弹性蛋白酶的抑制剂，其 IC50 值为 44 nM， Ki 值为 200 nM。Sivelestat (EI546) sodium tetrahydrate 有潜力用于 COVID-19的急性肺损伤/急性呼吸窘迫综合征或弥散性血管内凝血的研究。
T25131	AZD8309 AZD 8309,AZD-8309	Glutathione Peroxidase; CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism
	AZD8309 是一种强效的、可口服的趋化因子受体CXCR2的拮抗剂，能够调节中性粒细胞的转运，可显著降低胰腺和肺部的MPO，并降低胰腺内的胰蛋白酶和弹性蛋白酶活性。AZD8309 能够用于研究炎症系列疾病。
T10254	AE-3763	Serine Protease	Proteases/Proteasome
	AE-3763 is a peptide-based human neutrophil elastase inhibitor (IC50: 29 nM).
T15285	FK706	Serine Protease	Proteases/Proteasome
	FK706 is a slow-binding and competitive human neutrophil elastase inhibitor (IC50: 83 nM; Ki: 4.2 nM). FK706 also inhibits mouse neutrophil elastase and porcine pancreatic elastase (IC50s: 22 nM and 100 nM, respectively). FK706 has an anti-inflammatory ef
T17288	ZD8321	Serine Protease	Proteases/Proteasome
	ZD8321 is an effective inhibitor of human Neutrophil elastase (Ki: 13±1.7 nM).
T31877	Freselestat ONO-PO 736,ONO-6818,ONO 6818,ONO6818
	Freselestat (ONO-6818) is a potent neutrophil elastase inhibitor that significantly reduces the production of interleukin 8 and C5B-9. Freselestat reduces inflammatory mediators during simulated cardiopulmonary bypass.
T11865	Lodelaben 氯德拉苯,SC-39026,Declaben	Others	Others
	Lodelaben is a human neutrophil elastase inhibitor with an IC50 and Ki of 0.5 and 1.5 μM, respectively.
T25520	ICI 200355 ICI-200,355,ICI 200,355,ICI-200355,ICI200,355,ICI200355
	ICI 200355 is an inhibitor of human neutrophil elastase.
T24328	L 680833 L680,833,L680833,L-680,833,L 680,833,L-680833
	L 680833 is an orally active monocyclic beta-lactam human polymorphonuclear leukocyte elastase inhibitor.
T25782	MDL 27324 MDL-27,324,MDL-27324,MDL27,324,MDL 27,324,MDL27324
	MDL 27324 is an inhibitor of human neutrophil elastase.
T30303	BAY8040 BAY 8040,BAY-8040
	BAY8040 is a potent selective human neutrophilic elastase inhibitor with excellent potency and selectivity with promising pharmacokinetic characteristics.
T70767	SR 26831
	SR 26831 is a selective elastase inhibitor.
T34465	S 2484 S-2484,S2484,Pyro-glu-pro-val-pna
	S 2484 is a chromogranic specific granulocyte elastase substrate.
T25781	MDL 101146 MDL-101146,MD 101,146,MDL101146,MDL 101,146,MDL-101,146
	MDL 101146 is an orally active neutrophil elastase inhibitor.
T25518	Ici 186756 Ici186756,Ici--186756
	Ici 186756 is a novel, effective, and selective inhibitor of human neutrophil elastase.
T11525L	GW311616 hydrochloride GW311616A	Others	Others
	GW-311616 hydrochloride is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
T3107L	Alvelestat tosylate
	Alvelestat can inhibit neutrophil elastase (NE), which acts an important role in NET formation.
T15144	DMP 777 L-694458	Others	Others
	DMP 777 is an orally active inhibitor of human leukocyte elastase.
T25521	Ici 200880 Ici 200,880,Ici-200880,Ici200,880,Ic-200,880,Ici200880
	Ici 200880 is a human neutrophil elastase synthetic peptide inhibitor.
T69790	GW-475151
	GW-475151 inhibits human neutrophil elastase (HNE).
T25784L	MDL-101146, (S)- MDL101146, (S)-
	MDL-101146, (S)- is an effective orally active inhibitor of human neutrophil elastase.
T25784	MDL-101146, (R)- MDL101146, (R)-
	MDL-101146, (R)- is an effective orally active inhibitor of human neutrophil elastase.
T25880	Nostopeptin B
	Nostopeptin B is an inhibitor of elastase.
T20130	Elastatinal BRN0873543,BRN 0873543,BRN-0873543
	Elastatinal is an elastase inhibitor. It is found in culture filtrates of various species of actinomyces.
T62846	Freselestat quarterhydrate
	Freselestat quarterhydrate (ONO-6818 quarterhydrate) 是一种有效的、口服具有活力的嗜中性粒细胞弹性蛋白酶 (neutrophil elastase) 抑制剂 (Ki: 12.2 nM)。Freselestat quarterhydrate 对其他蛋白酶（例如胰蛋白酶，蛋白酶3，胰弹性蛋白酶，凝血酶，纤溶酶，胶原酶，组织蛋白酶G 和鼠巨噬细胞弹性蛋白酶）的活性低 100 倍以上，表现出有效的抗炎作用。
T68179	Neltenexine
	Neltenexine is an elastase inhibitor that may be useful for preventing pulmonary emphysema.
T27747	KRP-109 KRP 109,KRP109
	KRP-109, a neutrophil elastase (NE) inhibitor, acts by decreasing expression of TGF-ß Signal Related Genes.
T11525	GW311616	Others	Others
	GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).
T71198	Eglin c (60-63)
	Eglin c (60-63) is a sequence of a peptide that has been studied for its inhibitory activity towards human leukocyte elastase, cathepsin G, porcine pancreatic elastase and alpha-chymotrypsin.
T36351	Suc-AAP-Abu-pNA
	Suc-AAP-Abu-pNA 是胰腺弹性蛋白酶的特异性底物 (Km = 100 μM; Kcat/Km = 35,300 s-1 M-1 for rat pancreatic elastase; Km = 30 μM; Kcat/Km = 351,000 s-1 M-1 for porcine pancreatic elastase)。
T41043	Lonodelestat POL6014
	Lonodelestat (POL6014) is a potent, orally active and selective peptide inhibitor of human neutrophil elastase (hNE).

化合物

Elastase from porcine pancreas

Cat.No: T40495

Synonym: 弹性蛋白酶,EC 3.2.1.35

Target: Others

MeOSuc-AAPV-CMK

Cat.No: T78633

Synonym: Elastase Inhibitor III

Elastase-IN-1

Cat.No: T60855

Elastase LasB-IN-1

Cat.No: T82483

Neutrophil elastase inhibitor 4

Cat.No: T79397

Tyrosinase/elastase-IN-1

Cat.No: T74243

Cat.No: T12613L

Target: Serine Protease

Cat.No: T9964

Target: Others

Cat.No: T3107

Synonym: AZD9668,Avelestat

Target: Others, Serine Protease

Cat.No: TP1012

Synonym: Z-Ile-Glu-Pro-Phe-Ome

Target: Others

Cat.No: T6986

Synonym: ONO5046,EI546,西维来司他,LY544349

Target: Others, SARS-CoV, Serine Protease

Cat.No: T13389

Target: PI3K

Acetyltrialanine

Cat.No: T20163

2-(2-bromophenyl)-5-chloro-4H-3,1-benzoxazin-4-one

Cat.No: T8563

Target: Serine Protease

Cat.No: T68099

Synonym: MR-889

Target: Others

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE

Cat.No: T8602

Target: Serine Protease

3,4 Dichloroisocoumarin

Cat.No: T8677

Target: Others, Serine Protease, Cysteine Protease

MeOSuc-AAPV-AMC

Cat.No: T38364

Synonym: MeOSuc-Ala-Ala-Pro-Val-AMC

Cat.No: T10473

Target: Others

Sivelestat sodium tetrahydrate

Cat.No: T20762

Synonym: ONO-5046 sodium tetrahydrate,Elaspol,ONO 5046,ONO5046 sodium tetrahydrate,Elaspol sodium tetrahydrate,ONO-5046,Sivelestat Sodium,Sivelestat Sodium Hydrate,ONO5046

Target: Serine Protease

Cat.No: T25131

Synonym: AZD 8309,AZD-8309

Target: Glutathione Peroxidase, CXCR

Cat.No: T10254

Target: Serine Protease

Cat.No: T15285

Target: Serine Protease

Cat.No: T17288

Target: Serine Protease

Cat.No: T31877

Synonym: ONO-PO 736,ONO-6818,ONO 6818,ONO6818

Cat.No: T11865

Synonym: 氯德拉苯,SC-39026,Declaben

Target: Others

Cat.No: T25520

Synonym: ICI-200,355,ICI 200,355,ICI-200355,ICI200,355,ICI200355

Cat.No: T24328

Synonym: L680,833,L680833,L-680,833,L 680,833,L-680833

Cat.No: T25782

Synonym: MDL-27,324,MDL-27324,MDL27,324,MDL 27,324,MDL27324

Cat.No: T30303

Synonym: BAY 8040,BAY-8040

Cat.No: T70767

Cat.No: T34465

Synonym: S-2484,S2484,Pyro-glu-pro-val-pna

Cat.No: T25781

Synonym: MDL-101146,MD 101,146,MDL101146,MDL 101,146,MDL-101,146

Cat.No: T25518

Synonym: Ici186756,Ici--186756

GW311616 hydrochloride

Cat.No: T11525L

Synonym: GW311616A

Target: Others

Alvelestat tosylate

Cat.No: T3107L

Cat.No: T15144

Synonym: L-694458

Target: Others

Cat.No: T25521

Synonym: Ici 200,880,Ici-200880,Ici200,880,Ic-200,880,Ici200880

Cat.No: T69790

MDL-101146, (S)-

Cat.No: T25784L

Synonym: MDL101146, (S)-

MDL-101146, (R)-

Cat.No: T25784

Synonym: MDL101146, (R)-

Cat.No: T25880

Cat.No: T20130

Synonym: BRN0873543,BRN 0873543,BRN-0873543

Freselestat quarterhydrate

Cat.No: T62846

Cat.No: T68179

Cat.No: T27747

Synonym: KRP 109,KRP109

Cat.No: T11525

Target: Others

Eglin c (60-63)

Cat.No: T71198

Suc-AAP-Abu-pNA

Cat.No: T36351

Cat.No: T41043

Synonym: POL6014

Cat. No.	Product Name	Target	Signaling Pathways
TN1022	Secologanoside	Serine Protease	Proteases/Proteasome
	Secologanoside 来自于Poraqueiba sericea 的萜类化合物，对弹性蛋白酶抑制活性较低，IC50=164 μg/mL。它对成纤维细胞有中度细胞毒性。
T3S0381	Chrysophanol 8-O-glucoside	Serine Protease	Proteases/Proteasome
	Chrysophanol 8-O-glucoside 来自Rumex acetosa 根部，具有中等的弹性蛋白酶抑制特性。它具有温和的细胞毒性和抗糖尿病特性，能够在胰岛素刺激的葡萄糖转运途径中发挥代谢作用。
TJS0314	5,7-Dihydroxy-4-methylcoumarin Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin	Others; Antibacterial; Antifungal	Microbiology/Virology; Others
	5,7-Dihydroxy-4-methylcoumarin (Methyl-2H-Chromen-2-One) 是墨西哥龙蒿中的一种香豆素衍生物。它抑制人类中性粒细胞氧化代谢和弹性蛋白酶活性，有抗真菌和抗细菌活性。
TN4214	Hispanone
	Hispanone possesses anti-inflammatory activity, it shows inhibition of superoxide anion generation and elastase release.
TN3926	Eicosanyl caffeate	Others	Others
	Eicosanyl caffeate has anti-ulcer and moderate antioxidant properties, it exhibits potent elastase inhibitory activity, with the IC(50) value of 0.99 microg/mL.
T75619	Aristololactam IIIa
	Aristololactam IIIa 对超氧阴离子生成和弹性蛋白酶的释放有显著抑制作用，其 IC50值分别为 0.12 和 0.20 μg/mL。
TN3879	Docosyl caffeate
	Docosyl caffeate shows moderate antioxidant activity in DPPH and ABTS scavenging assays, it also has significant anti-inflammation activity. Docosyl caffeate exhibits potent elastase inhibitory activity, with the IC50 value of 1.4 microg/mL.
TN1556	Decarine	Antifection	Microbiology/Virology
	Decarine has high antibacterial activity against mycobacterial, gram-positive and gram-negative bacteria, and low cytotoxicity towards human macrophages.Decarine inhibits fMLP/CB-induced elastase release with IC(50) values < or = 5.53 microg/mL.
T75648	Rivulariapeptolides 1155
	Rivulariapeptolides 1155 是一种有效的丝氨酸蛋白酶 (serine protease) 抑制剂，对糜蛋白酶、弹性蛋白酶、蛋白蛋白酶 K 的 IC50分别为 41.84、4.94、56.54 nM。
TN4866	Pyracrenic acid	Others	Others
	Pyracrenic acid is a potent elastase inhibitor with an IC50 value of 1.5 mg/mL. Pyracrenic acid shows DPPH radical scavenging activity. It also shows significant cytotoxic activities against human cancer cells COLO 205 and AGS.
T75649	Rivulariapeptolides 1185
	Rivulariapeptolides 1185 是一种高效的选择性丝氨酸蛋白酶抑制剂，其对胰凝蛋白酶、弹性蛋白酶和蛋白酶 K 的 IC50分别为 13.17 nM、23.59 nM 和 55.26 nM。
TN4005	erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether	Serine Protease	Proteases/Proteasome
	erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether 是一种从巴西橡胶种子壳中提取的化合物，对人白细胞弹性蛋白酶具有抑制活性（IC50 ：171 umol/L）。
T75651	Rivulariapeptolides 988
	Rivulariapeptolides 988作为一种高效选择性丝氨酸蛋白酶抑制剂，对胰凝蛋白酶、弹性蛋白酶和蛋白酶K的IC50分别为95.46 nM、15.29 nM和85.50 nM。
T75652	Molassamide B
	Molassamide B，丝氨酸蛋白酶抑制剂，对胰凝乳蛋白酶、弹性蛋白酶及蛋白酶 K 具有显著抑制活性，其IC50值分别为24.65、11.69和5.42 nM。
T75650	Rivulariapeptolides 1121
	Rivulariapeptolides 1121，作为一种高效的选择性丝氨酸蛋白酶抑制剂，对胰凝蛋白酶、弹性蛋白酶和蛋白酶K展示出了显著的抑制活性，其IC50值分别为35.52 nM、13.24 nM和48.05 nM。
TN3706	Coronarin A
	Coronarin, A, B, C, and D are cytotoxic prinicples from the rhizomes of Hedychium coronarium, Zingiberaceae. Coronarin A exhibits good growth inhibition activities on HUVEC proliferation, it effectively suppresses the growth factor induced tube formation
TN4584	Morolic acid	IL Receptor; COX; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro

天然产物

Cat.No: TN1022

Target: Serine Protease

Chrysophanol 8-O-glucoside

Cat.No: T3S0381

Target: Serine Protease

5,7-Dihydroxy-4-methylcoumarin

Cat.No: TJS0314

Synonym: Methyl-2H-Chromen-2-One,5,7-二羟基-4-甲基香豆素,4-Methyllimetol,4-Methyl-5,7-Dihydroxycoumarin

Target: Others, Antibacterial, Antifungal

Cat.No: TN4214

Eicosanyl caffeate

Cat.No: TN3926

Target: Others

Aristololactam IIIa

Cat.No: T75619

Docosyl caffeate

Cat.No: TN3879

Cat.No: TN1556

Target: Antifection

Rivulariapeptolides 1155

Cat.No: T75648

Pyracrenic acid

Cat.No: TN4866

Target: Others

Rivulariapeptolides 1185

Cat.No: T75649

erythro-Guaiacylglycerol-beta-O-4'-dehydrodisinapyl ether

Cat.No: TN4005

Target: Serine Protease

Rivulariapeptolides 988

Cat.No: T75651

Cat.No: T75652

Rivulariapeptolides 1121

Cat.No: T75650

Cat.No: TN3706

Cat.No: TN4584

Target: IL Receptor, COX, HIV Protease

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03166	Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) PAE,lasB,Pseudolysin,Neutral metalloproteinase,Elastase<...	Pseudomonas aeruginosa	E. coli
	Cleaves host elastin, collagen, IgG, and several complement components as well as endogenous pro-aminopeptidase. Autocatalyses processing of its pro-peptide. Processes the pro-peptide of pro-chitin-binding protein (cbpD). Involved in the pathogenesis of P.aeruginosa infections. Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is P14756.
TMPH-01773	ELANE Protein, Human, Recombinant (GST) Neutrophil elastase,ELA2,Medullasin,Elastase	Human	E. coli
	Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae. ELANE Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 52.6 kDa and the accession number is P08246.
TMPH-02584	CELA3B Protein, Mouse, Recombinant (His & Myc) ELA3B,Chymotrypsin-like elastase family member 3B,P...	Mouse	P. pastoris (Yeast)
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Mouse, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 29.6 kDa and the accession number is Q9CQ52.
TMPH-01097	CELA3B Protein, Human, Recombinant (His) Elastase IIIB,ELA3B,Protease E,Elastase-3B...	Human	E. coli
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.3 kDa and the accession number is P08861.
TMPJ-00481	CELA3A Protein, Human, Recombinant (His) Elastase-3A,ELA3A,Elastase IIIA,CELA3A,Chy...	Human	HEK293 Cells
	Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little e...
TMPH-02583	CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc) Elastase-3B,Elastase IIIB,Protease E,Chymo...	Mouse	E. coli
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.1 kDa and the accession number is Q9CQ52.
TMPH-01094	CELA2A Protein, Human, Recombinant (His) Chymotrypsin-like elastase family member 2A,CELA2A,...	Human	P. pastoris (Yeast)
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P08217.
TMPH-01093	CELA2A Protein, Human, Recombinant (E. coli, His) Elastase-2A,CELA2A,Chymotrypsin-like elastase	Human	E. coli
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P08217.
TMPH-01096	CELA3A Protein, Human, Recombinant (His & SUMO) Elastase-3A,Protease E,ELA3,Chymotrypsin-like e...	Human	E. coli
	Efficient protease with alanine specificity but only little elastolytic activity. CELA3A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.6 kDa and the accession number is P09093.
TMPH-01095	CELA2B Protein, Human, Recombinant (His & SUMO) Chymotrypsin-like elastase family member 2B,ELA2B,<...	Human	E. coli
	Acts upon elastin. CELA2B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.8 kDa and the accession number is P08218.
TMPH-02582	CELA2A Protein, Mouse, Recombinant (His) Elastase-2A,ELA2A,CELA2A,Chymotrypsin-like elas...	Mouse	E. coli
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.7 kDa and the accession number is P05208.
TMPH-03466	Elastase-1 Protein, Salmo salar, Recombinant (His)	Salmo salar	E. coli
	Acts upon elastin. Elastase-1 Protein, Salmo salar, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.0 kDa and the accession number is Q7SIG3.
TMPH-03583	Extracellular elastase Protein, S. epidermidis, Recombinant (His & Myc)	Staphylococcus epidermidis	E. coli
	Protease that has a low substrate specificity. Glucagon is preferentially cleaved between aromatic (Phe) and hydrophobic (Val) amino acids. Hydrolyzes casein and elastin. Extracellular elastase Protein, S. epidermidis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.7 kDa and the accession number is P0C0Q4.
TMPH-03271	Complement factor D Protein, Rat, Recombinant (His & Myc) Adn,C3 convertase activator,Properdin factor D,Complement fa...	Rat	HEK293 Cells
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is P32038.
TMPH-03272	Complement factor D Protein, Rat, Recombinant (His) Adipsin,Df,Adn,C3 convertase activator,Complement factor D,E...	Rat	P. pastoris (Yeast)
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
TMPY-02869	MMP-12 Protein, Human, Recombinant (catalytic domain) HME,ME,MMP-12,MME,matrix metallopeptidase 12	Human	E. coli
	Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ...
TMPY-00672	Azurocidin/CAP37 Protein, Human, Recombinant (His) AZU,NAZC,azurocidin 1,hHBP,AZAMP,HUMAZUR,CAP37,HBP,AZU1	Human	HEK293 Cells
	Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is n...
TMPY-01909	Elafin Protein, Human, Recombinant (His) WAP3,ESI,peptidase inhibitor 3,SKALP,cementoin,MGC13613,WFDC...	Human	HEK293 Cells
	Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific si...
TMPH-03370	Serpin A3K Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	Binds to and inhibits kallikreins. Inhibits trypsin but not chymotrypsin or elastase. Serpin A3K Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 52.0 kDa and the accession number is P05545.
TMPJ-00452	Serpin A1a Protein, Mouse, Recombinant (His) Alpha-1-antitrypsin 1-1, Alpha-1 protease inhibitor 1, Alpha...	Mouse	HEK293 Cells
	Serpin A1a is also known as alpha-1-antitrypsin, is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a number of proteolytic processes. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin.
TMPH-03177	RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)	Pseudomonas aeruginosa	E. coli
	Necessary for transcriptional activation of the rhlAB genes encoding the rhamnosyltransferase. It also functions as a transcriptional activator of elastase structural gene (lasB). Binds to autoinducer molecules BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone). RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 47.6 kDa and the accession n...
TMPJ-01069	Serpin A1e Protein, Mouse, Recombinant (His) Dom5,α-1-antitrypsin 1-5,Serpina1e,Spi1-5,Serine protease in...	Mouse	HEK293 Cells
	Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein ...
TMPJ-00234	AMBP Protein, Human, Recombinant (His) α-1-Microglobulin,Uronic-Acid-Rich Protein,Inter-α-Trypsin I...	Human	HEK293 Cells
	Protein AMBP belongs to the calycin superfamily and Lipocalin family. AMBP can be cleaved into three chains: α-1-microglobulin, inter-α-trypsin inhibitor light chain and trypstatin. AMBP is expressed by the liver and secreted in plasma. α-1-microglobulin occurs in many physiological fluids including the plasma, urine, and cerebrospinal fluid. Inter-α-trypsin inhibitor is present in the plasma and urine. α-1-microglobulin occurs as a monomer and also in complexes with IgA and albumin, Inter-α-try...
TMPJ-00505	Serpin A1 Protein, Human, Recombinant (aa 25-418, His) Alpha-1-Antiproteinase,α-1-Antiproteinase,SERPINA1,Serpin A1...	Human	HEK293 Cells
	Serpin A1 is a prototype member of the Serpin superfamily of the serine protease inhibitors. As one of the most abundant proteinase inhibitors in the circulation, it is synthesized in hepatocytes, and to a lesser extent, in macrophages as well as intestinal epithelial cell lines and secreted as the abundant proteinase inhibitor in the circulation whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Point mutations in the native SerpinA1 variants re...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His) CTSV,cathepsin V,MGC125957,CATL2,CTSU,CTSL2	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and to a lesser extent in conjuctival epithelium and skin. It is a lysosomal cysteine proteinase that may play an important role in corneal physiology. It has about 75% protein sequence identity to murine cathepsin L. The fold of this enzyme is similar to the fold adopted by other mem...

重组蛋白

Elastase Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03166

Species: Pseudomonas aeruginosa

Expression System: E. coli

ELANE Protein, Human, Recombinant (GST)

Cat.No: TMPH-01773

Species: Human

Expression System: E. coli

CELA3B Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02584

Species: Mouse

Expression System: P. pastoris (Yeast)

CELA3B Protein, Human, Recombinant (His)

Cat.No: TMPH-01097

Species: Human

Expression System: E. coli

CELA3A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00481

Species: Human

Expression System: HEK293 Cells

CELA3B Protein, Mouse, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-02583

Species: Mouse

Expression System: E. coli

CELA2A Protein, Human, Recombinant (His)

Cat.No: TMPH-01094

Species: Human

Expression System: P. pastoris (Yeast)

CELA2A Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01093

Species: Human

Expression System: E. coli

CELA3A Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01096

Species: Human

Expression System: E. coli

CELA2B Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01095

Species: Human

Expression System: E. coli

CELA2A Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02582

Species: Mouse

Expression System: E. coli

Elastase-1 Protein, Salmo salar, Recombinant (His)

Cat.No: TMPH-03466

Species: Salmo salar

Expression System: E. coli

Extracellular elastase Protein, S. epidermidis, Recombinant (His & Myc)

Cat.No: TMPH-03583

Species: Staphylococcus epidermidis

Expression System: E. coli

Complement factor D Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03271

Species: Rat

Expression System: HEK293 Cells

Complement factor D Protein, Rat, Recombinant (His)

Cat.No: TMPH-03272

Species: Rat

Expression System: P. pastoris (Yeast)

MMP-12 Protein, Human, Recombinant (catalytic domain)

Cat.No: TMPY-02869

Species: Human

Expression System: E. coli

Azurocidin/CAP37 Protein, Human, Recombinant (His)

Cat.No: TMPY-00672

Species: Human

Expression System: HEK293 Cells

Elafin Protein, Human, Recombinant (His)

Cat.No: TMPY-01909

Species: Human

Expression System: HEK293 Cells

Serpin A3K Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03370

Species: Rat

Expression System: E. coli

Serpin A1a Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00452

Species: Mouse

Expression System: HEK293 Cells

RhlR Protein, Pseudomonas aeruginosa, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03177

Species: Pseudomonas aeruginosa

Expression System: E. coli

Serpin A1e Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01069

Species: Mouse

Expression System: HEK293 Cells

AMBP Protein, Human, Recombinant (His)

Cat.No: TMPJ-00234

Species: Human

Expression System: HEK293 Cells

Serpin A1 Protein, Human, Recombinant (aa 25-418, His)

Cat.No: TMPJ-00505

Species: Human

Expression System: HEK293 Cells

Cathepsin V Protein, Human, Recombinant (His)

Cat.No: TMPY-01249

Species: Human

Expression System: HEK293 Cells

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