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41
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35390 |
Magrolimab
Hu5F9-G4,Magrolimab (anti-CD47) |
Others | Others |
Magrolimab (Hu5F9-G4) 是一种人源化抗 CD47 IgG4 单克隆抗体,通过阻断CD47来展现其抗肿瘤活性,主要与CD47的 N 末端焦谷氨酸结合,可用于和其他化合物联合治疗复发性骨髓瘤。 | |||
T75720 |
Thrombospondin-1 (1016-1023) (human, bovine, mouse)
|
Apoptosis | Apoptosis |
Thrombospondin-1 (1016-1023) (human, bovine, mouse) 是 Thrombospondin-1 (TSP-1) 的一部分,是一种具有 CD47 激动作用的多肽。 | |||
T7400 |
RRX-001
|
Apoptosis; Dehydrogenase; Parasite | Apoptosis; Metabolism; Microbiology/Virology |
RRx-001 是一种低氧选择性的表观遗传因子,被用作放射或化疗敏感剂,能诱发凋亡,克服骨髓瘤的耐药性。它是G6PD 的有效抑制剂,具有抗疟、抗癌活性。它是免疫检查点的抑制剂,可下调CD47和SIRP-α。 | |||
T81695 |
NCGC00538431
|
||
NCGC00538431是一种用于调节SIRPα-CD47相互作用的化合物。 | |||
T76965 | Urabrelimab | ||
Urabrelimab (SRF231) 是一种完全人抗CD47单克隆抗体,可阻断 CD47-SIRP 相互作用。 | |||
T76732 | CC-90002 | ||
CC-90002 是一种人源化抗 CD47 单克隆抗体 (mAb)。CC-90002 与 CD47 具有高亲和力,具有亚纳摩尔 Kd 值。CC-90002 可用于血液系统恶性肿瘤和实体瘤的研究。 | |||
T78323 |
Letaplimab
IBI-188 |
||
Letaplimab (IBI-188) 是一种人源化IgG4单克隆抗CD47抗体,克隆标的CD47在癌细胞上过表达并作为SIRPα的配体。该药物通过增强对肿瘤细胞的吞噬作用发挥功效。 | |||
T80991 |
Thrombospondin-1 (1016-1021) (human, bovine, mouse)
|
||
Thrombospondin-1 (1016-1021) (human, bovine, mouse) 为无法与 CD47 结合的 Thrombospondin-1 派生截短肽。 | |||
T78246 |
Lemzoparlimab
TJC4,TJ011133 |
||
Lemzoparlimab(TJ011133;TJC4)是一种具有显著抗肿瘤活性的人源化抗CD47 IgG4抗体。 | |||
T81605 |
Ontorpacept
TTI-621 |
||
Ontorpacept (TTI-621)为一种由人SIRPα的N端(1-118)与人IgG1的Fc区域构建的可溶性融合蛋白。该N端片段为CD47结合域,而CD47为巨噬细胞吞噬作用的负调控器。作为CD47阻断剂和检查点抑制剂,Ontorpacept展现出抗肿瘤活性。 | |||
T72930 |
NCGC00138783
|
||
NCGC00138783,一种针对CD47/SIRPα轴的选择性抑制剂,IC50值为50 µM,作用机制为直接阻断CD47与SIRPα之间的相互作用。 | |||
T78144 |
NCGC00138783 TFA
|
Others | Others |
NCGC00138783 TFA,作为一种针对CD47/SIRPα轴的选择性抑制剂,具有50 μM的IC50值,能够直接干扰CD47与SIRPα之间的作用。 | |||
T73564 |
DMUP
|
||
DMUP 是一种有效的 CD47-SIRPα axis 抑制剂。DMUP 在 A549 细胞中诱导细胞凋亡 (apoptosis) 并增加巨噬细胞的吞噬作用。DMUP 降低 CD47 和 SIRPα 的蛋白表达水平。DMUP 显示出抗肿瘤活性。 | |||
T81155 |
Simridarlimab
|
||
Simridarlimab是一种针对CD274/CD47的人源化IG类抗体。 | |||
T77065 | Ligufalimab | ||
Ligufalimab (AK 117) 是一种人源化 IgG4抗 CD47 单克隆抗体 Ligufalimab 不诱导 RBC 血凝,而诱导吞噬作用。Ligufalimab 具有抗肿瘤活性。 | |||
T78276 |
KWAR 23
|
||
KWAR23为一种anti-human SIRPα抗体,能高亲和力结合human SIRPα并阻断其与CD47的相互作用。当与tumor-opsonizing抗体协同应用时,KWAR23展现出抗肿瘤活性,适用于癌症免疫治疗的研究。 | |||
T76497 |
KRFK
|
||
KRFK是一种源自TSP-1的多肽,具备激活TGF-β的能力。通过独立于TSP受体(例如CD47和CD36)的方式,KRFK能够促进TGF-β介导的信号传递以及其下游效应的发生,可作为慢性眼表炎症疾病研究的工具。 | |||
T78544 |
KRFK TFA
|
||
KRFK TFA为源自TSP-1的多肽,具有激活TGF-β的功能。它通过促进TGF-β介导的信号传递和下游效应发挥作用,而这种效应与TSP受体(如CD47和CD36)无关。KRFK TFA适用于研究慢性眼表炎症性疾病。 | |||
T63139 | Glutaminyl cyclases-IN-1 | ||
Glutaminyl cyclases-IN-1 (IsoQC-IN-1) 是一种谷氨酰胺酰基环化酶 (glutaminyl cyclases, QC) 的有效抑制剂,作用于人 QC (IC50: 12 nM) 和 isoQC (IC50: 73 nM)。Glutaminyl cyclases-IN-1 能够抑制 isoQC,进而选择性的阻碍 CD47/SIRPα 的相互作用,也可以提高 THP-1 和 U937 巨噬细胞的吞噬作用。 | |||
T82994 |
Anzurstobart
BMS-986351,CC-95251 |
||
Anzurstobart (CC-95251; BMS-986351) 是具有高亲和力的SIRPα全人源单克隆抗体,能够阻断CD47与SIRPα的结合。联合应用抗体利妥昔单抗时,Anzurstobart能增强巨噬细胞在共培养模型中对DLBCL细胞系的吞噬作用,显示出在实体和血液恶性肿瘤研究中的应用潜力。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05276 |
CD47 Protein, Cynomolgus, Recombinant (hFc)
CD47 molecule |
Cynomolgus | HEK293 Cells |
CD47 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is A0A2K5X4H8. | |||
TMPY-03093 |
CD47 Protein, Rat, Recombinant (His)
CD47 molecule |
Rat | HEK293 Cells |
CD47 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is P97829-1. | |||
TMPJ-00211 |
CD47 Protein, Human, Recombinant (His)
MER6,Integrin-Associated Protein,Leukocyte Surface Antigen <... |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and the accession number is Q08722. | |||
TMPY-05343 |
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His)
CD47 molecule |
Cynomolgus,Rhesus | HEK293 Cells |
CD47 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is XP_005548291.1&NP_001253446.1. | |||
TMPY-04683 |
CD47 Protein, Human, Recombinant
MER6,CD47 molecule,OA3,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-04935 |
CD47 Protein, Human, Recombinant (aa 1-139, His)
MER6,CD47 molecule,IAP,OA3 |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3. | |||
TMPY-05191 |
CD47 Protein, Human, Recombinant, Biotinylated
CD47 molecule,MER6,OA3,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-04810 |
CD47 Protein, Mouse, Recombinant (His)
AA407862,CD47 molecule,AW108519,9130415E20... |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is Q61735-1. | |||
TMPY-03002 |
CD47 Protein, Rat, Recombinant (hFc)
CD47 molecule |
Rat | HEK293 Cells |
CD47 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.8 kDa and the accession number is P97829. | |||
TMPK-00644 |
CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47,OA3,IAP,CD47 molecu... |
Cynomolgus,Rhesus | HEK293 Cells |
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα).CD-47 acts as a don't eat me signal to macrophages of the immune system which has made it a potential therapeutic target in some cancers. | |||
TMPY-03883 |
CD47 Protein, Human, Recombinant (hFc)
OA3,CD47 molecule,IAP,MER6 |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3. | |||
TMPJ-00212 |
CD47 Protein, Human, Recombinant (mFc)
CD47,IAP,Integrin-associated protein,Antig... |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 48-65 KDa and the accession number is Q08722. | |||
TMPJ-00614 |
CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
MER6,Integrin-Associated Protein,IAP,Leukocyte Surface Antig... |
Rhesus | HEK293 Cells |
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral membrane protein that consists of a extracellular domain (ECD) with a single Ig‑like domain, five membrane-spanning regions with short intervening loops, and C‑terminal cytoplasmic tail. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It plays an important r... | |||
TMPY-05378 |
CD47 Protein, Mouse, Recombinant (hFc)
9130415E20Rik,AA407862,B430305P08Rik,Itgp,CD47<... |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number is Q3U967. | |||
TMPY-05467 |
CD47 Protein, Mouse, Recombinant
B430305P08Rik,AA407862,IAP,Itgp,9130415E20Rik,CD |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.8 kDa and the accession number is E5Q371. | |||
TMPJ-00613 |
CD47 Protein, Rhesus macaque, Recombinant (hFc)
Protein MER6,Integrin-Associated Protein,MER6,IAP,CD |
Rhesus | HEK293 Cells |
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accession number is F7A802. | |||
TMPY-04992 |
CD47 Protein, Mouse, Recombinant (rFc)
9130415E20Rik,AI848868,IAP,AA407862,AW108519,B430305P08Rik,I... |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 39.9 kDa and the accession number is Q3U967. | |||
TMPJ-00209 |
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated
Protein MER6,Integrin-Associated Protein,MER6,CD |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is Q08722. | |||
TMPJ-00208 |
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Protein MER6,MER6,IAP,CD47,Antigenic surfa... |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is Q08722. | |||
TMPY-06367 |
CD47 Protein, Human, Recombinant (aa 19-139, His)
OA3,CD47 molecule,MER6,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (aa 19-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.17kDa and the accession number is NP_942088.1. | |||
TMPY-06328 |
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated
B430305P08Rik,AA407862,IAP,Itgp,CD47 molec... |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.1 kDa and the accession number is Q61735-1. | |||
TMPK-01356 |
SIRP alpha V4 Protein, Human, Recombinant (His & Avi)
BIT,SIRP α V4,MFR,SHPS1,SIRPA,SIRP α,P84,MYD1,MYD-1,PTPNS1,S... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-00250 |
SIRP gamma Protein, Human, Recombinant (His & Avi)
SIRP-B2,bA77C3.1,CD172g,SIRP β 2,SIRP gamma,SIRP be... |
Human | HEK293 Cells |
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Hum... | |||
TMPK-00307 |
SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated
SHPS1,SIRP alpha,SHPS-1,SIRPA,MYD-1,BIT,CD172a,MYD1... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha Protein, Human, Recombinant (aa 31-370, hFc & Avi), Biotinylated is expressed in HEK293 mam... | |||
TMPK-00628 |
SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,SIRP alpha,MYD-1,SIRP α,SHPS-1,SIRPA,SHPS1,MFR,SIRP α V3... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00611 |
SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His)
MYD-1,SHPS1,MFR,PTPNS1,CD172a,SIRPA,SIRP α V2/C... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (aa 31-369, His) is expressed in HEK293 mammalian cells with... | |||
TMPK-01363 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP alpha,MFR,PTPNS1,SIRP α V5,P84,SHPS-1,BIT,CD17... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01358 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
P84,SIRPA,SIRP alpha,SHPS-1,MFR,BIT,MYD1,SIRP α V6,SHPS1,SIR... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01364 |
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP α,MFR,SHPS1,SIRPA,BIT,SHPS-1,MYD-1,SIRP alpha,P84,C... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00251 |
SIRP gamma Protein, Human, Recombinant (His & Avi), Biotinylated
SIRP β2,bA77C3.1,SIRP γ/CD172g,SIRP beta 2,SIRP-B2,... |
Human | HEK293 Cells |
Signal regulatory protein gamma (SIRP gamma, designated CD172g), also called SIRP beta 2, is a monomeric 45-47 kDa type I transmembrane protein belonging to the SIRP/SHPS (CD172) family of the Ig superfamily.SIRP gamma is probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRP gamma Protein, Hum... | |||
TMPJ-00248 |
SIRP gamma Protein, Human, Recombinant (hFc)
SIRP-Gamma,SIRP-β-2,SIRP-Beta-2,Signal-Regulatory Protein Ga... |
Human | HEK293 Cells |
Signal-Regulatory Protein Gamma (SIRPG) is a member of the signal-regulatory protein (SIRP) family and also belongs to the immunoglobulin superfamily. SIRPG is detected in the liver, and at very low levels in the brain, heart, lung, pancreas, kidney, placenta, and skeletal muscle. SIRPG is an immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell prol... | |||
TMPK-00627 |
SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,MFR,MYD1,SHPS-1,SIRP alpha,SIRP α,SIRPα,MYD-1,PTPNS1,SIR... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00626 |
SIRP alpha V8 Protein, Human, Recombinant (His & Avi)
SIRP alpha,P84,MYD1,MYD-1,SHPS1,BIT,SIRP α V8,PTPNS1,SIRPA,M... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V8 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-00610 |
SIRP alpha V2 Protein, Human, Recombinant (hFc)
PTPNS1,MYD-1,MFR,SHPS1,SIRPalpha2,SIRPα2,SIRPA,SIRP α V2/ |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag.... | |||
TMPK-00609 |
SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated
P84,PTPNS1,SIRPαV2,SIRPalpha V2,CD172a,MYD1,MYD-1,S... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-00625 |
SIRP alpha V3 Protein, Human, Recombinant (His & Avi)
P84,SIRP alpha,CD172a,MFR,MYD-1,PTPNS1,SIRPA,SHPS1,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPK-01362 |
SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated
MYD1,SIRP α V4,PTPNS1,BIT,SHPS1,SIRP alpha,SHPS-1,SIRP α,MFR... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction. SIRP alpha V4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian c... | |||
TMPK-01357 |
SIRP alpha V5 Protein, Human, Recombinant (His & Avi)
MFR,PTPNS1,P84,BIT,MYD-1,MYD1,SHPS-1,SIRPA,SIRP α,SIRP α V5,... |
Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don´t eat me" signal. | |||
TMPJ-00305 |
SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)
Inhibitory Feceptor SHPS-1,MyD-1 Antig,Brain Ig-Like Molecul... |
Cynomolgus | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ... | |||
TMPJ-01182 |
SIRP alpha Protein, Mouse, Recombinant (MIgG2a)
SIRP,CD172 Antigen-Like Family Member A,SIRPA,MFR,S... |
Mouse | HEK293 Cells |
SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bovine, and porcine SIRP alpha, respectively.SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-l... | |||
TMPJ-00306 |
SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Brain Ig-Like Molecule with Tyrosine-Based Activation Motifs... |
Human | HEK293 Cells |
Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRPα acts as docking ... |