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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T26830 BK 129

BK-129,BK129

BK 129 is a local anesthetic with relaxant properties. BK 129 inhibits Ca2+ entry into the smooth muscle cell and Ca2+ release from sarcoplasmic reticulum.
T30481 BK 218

BK218,BK-218

BK 218 is a novel cephalosporin, which is active against streptococcus pneumoniae, Haemophilus influenza, and Moraxella catarrase, but has a higher MIC against penicillin-resistant strains. Bk-218 has dual administration routes and the activity spectrum m
T72905 cyclo(RLsKDK)

BK-1361

Cyclo(RLsKDK) (BK-1361) 作为ADAM8金属蛋白酶的特异性抑制剂,展示出182 nM的IC50值。其在炎性疾病和癌症治疗中显示出潜在的应用价值。
T24986 6bK

6 bK,6-bK,IDE inhibitor 6bK,IDE-IN-6bK,IDE-inhibitor-6bK

6bK is an inhibitor of insulin degrading enzyme (IDE).
T20782 Triazinetriethanol

Grotan BK,Grotan,Actane

Triazinetriethanol is a bactericidal agent used in coolant liquids.
T30650 C.I. 15690

Chrome Black BK,Eriochrome Black SR

C.I. 15690 is a dye.
T8747 Levofloxacin hydrochloride

DNA gyrase; Topoisomerase DNA Damage/DNA Repair
Levofloxacin hydrochloride 是一种广谱的第三代氟喹诺酮类抗生素,是氧氟沙星的光学活性 L-异构体,具有抗菌活性。左氧氟沙星通过细菌细胞壁扩散并通过抑制 DNA 促旋酶(细菌拓扑异构酶 II)起作用,这是一种 DNA 复制、RNA 转录和细菌 DNA 修复所需的酶。 DNA 促旋酶活性的抑制导致细菌细胞生长受阻。
T83688 R 715 TFA

[Ac-Lys-[D-βNal7,Ile8]des-Arg9]-BK,Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile-OH

R 715是一种布拉迪肾上腺素B1受体拮抗剂。它抑制在表达布拉迪肾上腺素B1受体的孤立人类脐带中由布拉迪肾上腺素引发的收缩(pA2 = 8.49)。R 715(200、400及600 µg/kg)通过尾部闪烁测试减少了由链脲佐菌素(STZ)诱导的糖尿病神经病变小鼠模型中尾部撤回的潜伏期。它还在以髓磷脂少突胶质细胞糖蛋白(MOG)(35-55)(MOG35-55)抗原肽诱导的实验性自体免疫性脑炎(EAE)小鼠模型中,通过每天1 mg/kg的剂量减少了后肢无力和瘫痪的发病率,改善对称步态,并减少脊髓炎症灶点数、神经元脱髓鞘以及病灶单核细胞侵袭。R 715(0.01 nmol/动物,脑室内)能在自发性高血压大鼠中降低平均动脉血压并增加心率。
T78982 BK60106

Apoptosis Apoptosis
BK60106是一种选择性针对CD99的抑制剂,能够直接与CD99的胞外结构域结合。它能特异性地诱导尤文肉瘤(ES)细胞凋亡(apoptosis),而且伴随的DNA损伤相对较少。
T74865 BK50164

BK50164 是一种有效的CD73抑制剂,IC50值为 13.089 µM。BK50164 与 CD99 结合KD 值为 1.5 µM。BK50164 显示抗增殖活性。BK50164 诱导细胞凋亡 (Apoptosis) 和细胞周期停滞在 Sub-G1 阶段。
T1451 Levofloxacin hydrate

左氧氟沙星半水合物,Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate

DNA gyrase; Topoisomerase; Antibacterial; Antibiotic DNA Damage/DNA Repair; Microbiology/Virology
Levofloxacin hydrate (Cravit hydrate) 是抗生素化合物,抑制细菌DNA 旋转酶活性。
T6060L Anabasine HCl

BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653

Anabasine HCl is used as a clinical biomarker for tobacco smoke exposure and as an insecticide. It is also a depolarizing NMJ blocker, aromatase inhibitor, nAChr antagonist, and teratogen found in species of Nicotiana.
T36095 Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)

Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)

Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt) 可用于生命科学领域的相关研究,其产品编号为 T36095。
T7951 TBK1/IKKε-IN-5

IκB/IKK NF-κB
TBK1/IKKε-IN-5 是一种 TBK1 (IC50:1 nM) 和 IKKε (IC50:5.6 nM) 的双抑制剂。
T15559 TBK1/IKKε-IN-2

IκB/IKK NF-κB
TBK1/IKKε-IN-2 是双重TBK1和IKKε抑制剂。
T73322 TBK1-IN-1

IκB/IKK NF-κB
TBK1-IN-1 是一种具有特异性和高效性的 TANK 结合激酶 1 (TBK1) 抑制剂(IC50: 22.4 nM),具有抗癌活性。TBK1-IN-1 对 TBK1 下游靶基因 cxcl10 和 ifnβ 的表达有抑制作用。
T60086 TTBK1-IN-2

N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Microtubule Associated Cytoskeletal Signaling
TTBK1-IN-2 (N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine) 是 Tau-Tubulin 激酶 (TTBK1) 的抑制剂,IC50 为 0.24 和 4.22 µM。 TTBK1-IN-2 降低细胞培养物和转基因 TDP-43 小鼠脊髓中的 TDP-43 磷酸化。
T75107 CrBKA

CrBKA 是SIRT6的弱活性荧光小分子底物。
T26833 BKM-570

BKM-570, a bradykinin antagonist, causes impressive growth inhibition of lung and prostate tumors.
T26831 BKM1644

BKM 1644,BKM-1644

BKM1644 is an effective inhibition of the proliferation of metastatic, castration-resistant PCa (mCRPC) cells.
T38263 TBK1/IKKε-IN-4

TBK1/IKKε-IN-4

TBK1/IKKε-IN-4 is a 6-aminopyrazolopyrimidine derivative and a potent, selective TBK1 and IKKε inhibitor with IC50 values of 13 nM and 59 nM, respectively. TBK1/IKKε-IN-4 shows 100- to 1000-fold less activity against other protein kinases including PDK1, PI3K family members and mTOR[1]. TBK1/IKKε-IN-4 (Compound II; 96 hours; A549 andHCC44 cells) treatmentdisplays selective toxicity in TBK1-dependent cancer cell lines (IC50 of ~ 4.2 μM for H441 cells and IC50 of ~0.4 μM for A549 cells)[1].TBK1/IK...
T72808 (R)-TTBK1-IN-1

TTBK1-IN-1 是一种强效、选择性、脑渗透型 tau 微管蛋白激酶 1 (TTBK1) 抑制剂。(R)-TTBK1-IN-1 是 TTBK1-IN-1 的对映体。TTBK1-IN-1 可用于阿尔茨海默病及相关疾病的研究。
T38598 CBK289001

CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5b MV , TRAP 5b OX and TRAP 5a OX with IC 50 s of 125 μM, 4.21 μM and 14.2 μM, respectively.
T36247 TBK1 control PROTAC® 4

Negative control for TBK1 PROTAC 3i. Binds TBK1 with high affinity, but exhibits no significant degradation of TBK1. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.
T40348 TTBK1-IN-1

TTBK1-IN-1

TTBK1-IN-1 is a highly potent and selective inhibitor of tau tubulin kinase 1 (TTBK1), capable of penetrating the blood-brain barrier with ease. With an IC 50 value of 2.7 nM, TTBK1-IN-1 exhibits strong inhibitory activity against TTBK1. This compound holds great promise for advancing research in Alzheimer's disease and other tauopathies.
T13097 TBK1/IKKε-IN-1

IκB/IKK NF-κB
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
T39841 TBK1/IKKε-IN-6

TBK1/IKKε-IN-6

TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.
T10556 BKI-1369

EGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
BKI-1369 is a bumped kinase inhibitor. BKI-1369 increases hERG-inhibitory activity (IC50:1.52 μM).
T26832 BKM1740

BKM-1740,BKM 1740

BKM1740 induced apoptosis in prostate cancer (PCa) cells by repressing survivin at both the mRNA and protein levels in vitro.
T16370 OABK hydrochloride

Others Others
OABK hydrochloride is a small-molecule switch. It also can be used to control protein activity.
T28222 5-Hydroxy-1-methylhydantoin

HD-003,HD003,5-羟基-1-甲基咪唑啉-2,4-二酮,NZ419,NZ-419,HD 003,NZ 419

Bradykinin Receptor GPCR/G Protein
5-Hydroxy-1-methylhydantoin (HD-003) 是一种可能用于治疗肾衰竭的抗氧化剂。它是肌酐代谢物,是一种羟基自由基清除剂,此前已显示通过抑制大鼠慢性肾病的进展来提供肾脏保护。 它是一种新型抗氧化药物,可完全抑制 B2-激肽受体(B2KR) 对 VSMC 中高葡萄糖 (25 mM) 刺激的反应,并且还显示可减弱 BK 对 VSMC 重塑的影响。它抑制 BK 诱导的 MAPK 磷酸化增加并减弱 VSMC 中结缔组织生长因子 (CTGF) 蛋白水平的增加。这些研究结果表明,它可能通过其抗氧化特性赋予血管保护免受高葡萄糖浓度和 BK 刺激以改善血管损伤和重塑。
T4612 NS309

EGFR; Potassium Channel; HER Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
NS309 是选择性钙依赖性钾离子通道 SK/IK 的激活剂,在 BK 通道上没有激活作用。
T3102 NS-1619

Apoptosis; Potassium Channel Apoptosis; Membrane transporter/Ion channel
NS 1619 是 Ca2+激活的 K+(BK) 通道的激活剂,是一种高效的松弛剂,在血管和其他组织的几个平滑肌中的 EC50约为 10 – 30 μM。它抑制A2780卵巢癌细胞增殖并诱导细胞凋亡。
T12255 NS19504

Potassium Channel Membrane transporter/Ion channel
NS19504 是 Ca2+激活的 K+通道激活剂 (EC50=11.0 µM),对膀胱平滑肌自发性相位收缩具有松弛作用。
T24065 FK-3657

FK 3657,FK3657,FR-173657,FR 173657,FR173657

FK-3657 is a non-peptide antagonist of bradykinin (BK)-B2 receptor.
T24137 HENA

HENA is a novel activator of large conductance, voltage- and Ca2+-gated K+ (BK) channels.
T37294 GoSlo-SR-5-69

BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).
T40650 Dihydroisopimaric acid

Dihydroisopimaric acid activates BK channels alphabeta1, which are large conductance Ca 2+ activated K + channels. This compound directly measures the opening of BKalphabeta1 under a whole-cell voltage clamp.
TP1725 Bradykinin (1-5)

Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE).The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurring metabolites. Bradykinin (1-5) m
T75998 cyclo(RLsKDK) TFA

cyclo(RLsKDK) (TFA) (BK-1361 (TFA)) 是一种特异性的金属蛋白酶 ADAM8抑制剂,IC50值为 182 nM。cyclo(RLsKDK) (TFA) 在炎性疾病和癌症中有潜在应用。
T70224 Bupivacaine tartrate

Bupivacaine is a BK/SK, Kv1, Kv3, TASK-2 K Channel and voltage-gated Na channel blocker used as an anesthetic. It maybe neurotoxic at high does, inducing apoptosis in neuroblastoma cells. It acts by binding to the intracellular portion of voltage-gated sodium channels and blocking sodium influx into nerve cells.
T40750 12,14-Dichlorodehydroabietic acid

12,14-Dichlorodehydroabietic acid, a chlorinated resin acid, exhibits potent calcium-activated potassium (BK) channel opening activity. It effectively inhibits GABA-dependent chloride influx in the mammalian brain, functioning as a non-competitive antagonist of GABA A receptors. Moreover, 12,14-Dichlorodehydroabietic acid induces an elevation in cytosolic free calcium levels and promotes the release of neurotransmitters.
T76169 Angiotensin-converting enzyme

Angiotensin-converting enzyme (ACE)血管紧张素转换酶是一种二羧基肽酶,它将非活性的血管紧张素 I (Ang I) 转化为活性的 Ang II,并降解活性的缓激肽 (BK)。Angiotensin-converting enzyme 是一种有效的血管收缩剂,常用于生化研究。
T37808 Kaliotoxin

aliotoxin是神经BK型肽基的抑制剂,对Kv通道和钙激活的钾通道能产生特异性抑制。Kaliotoxin对细胞膜电位和神经元兴奋性的调控具有研究意义。其产品编号为 T37808,CAS号为 145199-73-1
T83868 (±)13,14-EDT

(±)13,14-Epoxydocosatrienoic Acid,(±)13,14-EpDoTrE,(±)-Dihomo-13,14-EET

(±)13,14-EDT是一种氧脂和腎上腺酸的代谢产物,通过细胞色素P450(CYP)途径形成。在50 nM的浓度下,它能激活分离的大鼠冠状小动脉平滑肌细胞中的大导电钙激活钾通道(KCa1.1/BK),并导致分离的猪小动脉扩张(EC50 = 12 pM)。(±)13,14-EDT还能使用TP受体激动剂U-46619预收缩的分离牛冠状动脉放松。
T36215 17R(18S)-EpETE

17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases ...

化合物

BK 129
Cat.No: T26830
Synonym: BK-129,BK129
Target:
BK 218
Cat.No: T30481
Synonym: BK218,BK-218
Target:
cyclo(RLsKDK)
Cat.No: T72905
Synonym: BK-1361
Target:
6bK
Cat.No: T24986
Synonym: 6 bK,6-bK,IDE inhibitor 6bK,IDE-IN-6bK,IDE-inhibitor-6bK
Target:
Triazinetriethanol
Cat.No: T20782
Synonym: Grotan BK,Grotan,Actane
Target:
C.I. 15690
Cat.No: T30650
Synonym: Chrome Black BK,Eriochrome Black SR
Target:
Levofloxacin hydrochloride
Cat.No: T8747
Synonym:
Target: DNA gyrase, Topoisomerase
R 715 TFA
Cat.No: T83688
Synonym: [Ac-Lys-[D-βNal7,Ile8]des-Arg9]-BK,Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile-OH
Target:
BK60106
Cat.No: T78982
Synonym:
Target: Apoptosis
BK50164
Cat.No: T74865
Synonym:
Target:
Levofloxacin hydrate
Cat.No: T1451
Synonym: 左氧氟沙星半水合物,Levaquin hydrate,Cravit hydrate,Quixin hydrate,Levofloxacin Hemihydrate,Tavanic hydrate,Iquix hydrate
Target: DNA gyrase, Topoisomerase, Antibacterial, Antibiotic
Anabasine HCl
Cat.No: T6060L
Synonym: BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653
Target:
Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)
Cat.No: T36095
Synonym: Histone H2BK12ac (1-22)-GGK-biotin amide (trifluoroacetate salt)
Target:
TBK1/IKKε-IN-5
Cat.No: T7951
Synonym:
Target: IκB/IKK
TBK1/IKKε-IN-2
Cat.No: T15559
Synonym:
Target: IκB/IKK
TBK1-IN-1
Cat.No: T73322
Synonym:
Target: IκB/IKK
TTBK1-IN-2
Cat.No: T60086
Synonym: N-[4-(4-chlorophenoxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Target: Microtubule Associated
CrBKA
Cat.No: T75107
Synonym:
Target:
BKM-570
Cat.No: T26833
Synonym:
Target:
BKM1644
Cat.No: T26831
Synonym: BKM 1644,BKM-1644
Target:
TBK1/IKKε-IN-4
Cat.No: T38263
Synonym: TBK1/IKKε-IN-4
Target:
(R)-TTBK1-IN-1
Cat.No: T72808
Synonym:
Target:
CBK289001
Cat.No: T38598
Synonym:
Target:
TBK1 control PROTAC® 4
Cat.No: T36247
Synonym:
Target:
TTBK1-IN-1
Cat.No: T40348
Synonym: TTBK1-IN-1
Target:
TBK1/IKKε-IN-1
Cat.No: T13097
Synonym:
Target: IκB/IKK
TBK1/IKKε-IN-6
Cat.No: T39841
Synonym: TBK1/IKKε-IN-6
Target:
BKI-1369
Cat.No: T10556
Synonym:
Target: EGFR
BKM1740
Cat.No: T26832
Synonym: BKM-1740,BKM 1740
Target:
OABK hydrochloride
Cat.No: T16370
Synonym:
Target: Others
5-Hydroxy-1-methylhydantoin
Cat.No: T28222
Synonym: HD-003,HD003,5-羟基-1-甲基咪唑啉-2,4-二酮,NZ419,NZ-419,HD 003,NZ 419
Target: Bradykinin Receptor
NS309
Cat.No: T4612
Synonym:
Target: EGFR, Potassium Channel, HER
NS-1619
Cat.No: T3102
Synonym:
Target: Apoptosis, Potassium Channel
NS19504
Cat.No: T12255
Synonym:
Target: Potassium Channel
FK-3657
Cat.No: T24065
Synonym: FK 3657,FK3657,FR-173657,FR 173657,FR173657
Target:
HENA
Cat.No: T24137
Synonym:
Target:
GoSlo-SR-5-69
Cat.No: T37294
Synonym:
Target:
Dihydroisopimaric acid
Cat.No: T40650
Synonym:
Target:
Bradykinin (1-5)
Cat.No: TP1725
Synonym:
Target:
cyclo(RLsKDK) TFA
Cat.No: T75998
Synonym:
Target:
Bupivacaine tartrate
Cat.No: T70224
Synonym:
Target:
12,14-Dichlorodehydroabietic acid
Cat.No: T40750
Synonym:
Target:
Angiotensin-converting enzyme
Cat.No: T76169
Synonym:
Target:
Kaliotoxin
Cat.No: T37808
Synonym:
Target:
(±)13,14-EDT
Cat.No: T83868
Synonym: (±)13,14-Epoxydocosatrienoic Acid,(±)13,14-EpDoTrE,(±)-Dihomo-13,14-EET
Target:
17R(18S)-EpETE
Cat.No: T36215
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6567 Levofloxacin

Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin

Topoisomerase; Antibacterial; Antibiotic DNA Damage/DNA Repair; Microbiology/Virology
Levofloxacin (Fluoroquinolone) 是合成的氟喹诺酮类抗生素,有抑制细菌DNA 旋转酶的超螺旋活性的作用,能阻止DNA 复制。
T12373 Paxilline

Others Others
Paxilline is an indole alkaloid mycotoxin from Penicillium paxilli, acts as a potent BK channels inhibitor by an almost exclusively closed-channel block mechanism. Paxilline possesses significant anticonvulsant activity.
T12403 Penitrem A

Others Others
Penitrem A is a selective antagonist of BK channel with antiproliferative and anti-invasive activities against multiple malignancies.

天然产物

Levofloxacin
Cat.No: T6567
Synonym: Levaquin,Cravit,Tavanic,Fluoroquinolone,左氧氟沙星,(-)-Ofloxacin
Target: Topoisomerase, Antibacterial, Antibiotic
Paxilline
Cat.No: T12373
Synonym:
Target: Others
Penitrem A
Cat.No: T12403
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-01598 Kininogen 1 Protein, Human, Recombinant (His)

kininogen 1,KNG,BK,BDK

Human HEK293 Cells
Kininogen 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is P01042-1.
TMPH-00201 BK polyomavirus (BKPyV) VP2 Protein (His)

Minor capsid protein VP2,Minor structural protein VP2

BKPyV E. coli
Isoform VP2 is a structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers. Participates in host cell receptor binding together with VP1. Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane. Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm. Nuclear entry of the viral DNA ...
TMPH-00200 BK polyomavirus (BKPyV) VP1 Protein (His & Myc)

Major structural protein VP1,Major capsid protein VP1

BKPyV E. coli
BK polyomavirus (BKPyV) VP1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 45.1 kDa and the accession number is P03088.
TMPH-01531 IKBKB Protein, Human, Recombinant (His)

Human Baculovirus Insect Cells
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In tu...
TMPY-04769 RBKS Protein, Human, Recombinant (His)

ribokinase,RBSK

Human E. coli
RBKS Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H477-1.
TMPH-01532 IKBKB Protein, Human, Recombinant (E. coli, His)

Human E. coli
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In tu...
TMPY-04547 PBK/TOPK Protein, Human, Recombinant (His)

HEL164,Nori-3,CT84,TOPK,PDZ binding kinase,SPK

Human Baculovirus Insect Cells
PDZ binding kinase (PBK), also known as TOPK (T-LAK cell-originated protein kinase), is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family, and has all the characteristic protein kinase subdomains and a C-terminal PDZ-binding T/SXV motif. PBK is expressed in the testis restrictedly expressed in outer cell layer of seminiferous tubules, as well as placenta. PBK may be enrolled in the activation of lymphoid cells and support testicular fun...
TMPH-02180 TTBK2 Protein, Human, Recombinant (His & Myc)

Human E. coli
Serine/threonine kinase that acts as a key regulator of ciliogenesis: controls the initiation of ciliogenesis by binding to the distal end of the basal body and promoting the removal of CCP110, which caps the mother centriole, leading to the recruitment of IFT proteins, which build the ciliary axoneme. Has some substrate preference for proteins that are already phosphorylated on a Tyr residue at the +2 position relative to the phosphorylation site. Able to phosphorylate tau on serines in vitro.

重组蛋白

Kininogen 1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01598
Species: Human
Expression System: HEK293 Cells
BK polyomavirus (BKPyV) VP2 Protein (His)
Cat.No: TMPH-00201
Species: BKPyV
Expression System: E. coli
BK polyomavirus (BKPyV) VP1 Protein (His & Myc)
Cat.No: TMPH-00200
Species: BKPyV
Expression System: E. coli
IKBKB Protein, Human, Recombinant (His)
Cat.No: TMPH-01531
Species: Human
Expression System: Baculovirus Insect Cells
RBKS Protein, Human, Recombinant (His)
Cat.No: TMPY-04769
Species: Human
Expression System: E. coli
IKBKB Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01532
Species: Human
Expression System: E. coli
PBK/TOPK Protein, Human, Recombinant (His)
Cat.No: TMPY-04547
Species: Human
Expression System: Baculovirus Insect Cells
TTBK2 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-02180
Species: Human
Expression System: E. coli
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