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366

抑制剂 & 化合物

32

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Cat. No.	Product Name	Target	Signaling Pathways
TP1528	Angiotensin I/II (1-5) Angiotensin I/II 1-5	RAAS; Others	Endocrinology/Hormones; Others
	Angiotensin I/II (1-5) 是由血管紧张素 I/II 肽转化而来，有 1-5 个氨基酸组成的多肽。血管紧张素 I 是由肾素对血管紧张素原的作用形成的，血管紧张素 I 可产生血管紧张素 II 。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
T7339	Angiotensin (1-7) Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO	RAAS; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) 是肾素-血管紧张素系统中的内源性七肽。Angiotensin 1-7在心肌细胞中具有抗炎和抗纤维化活性，因此具有心脏保护作用。它能抑制血管紧张素转换酶和释放一氧化氮，是激肽诱导的血管舒张的局部协同调节剂。它阻断 Ang II 诱导的平滑肌细胞增殖和肥大，并显示对内皮的抗血管生成和生长抑制作用。它显示出抗炎活性。
TP1579	Angiotensin I/II (1-6) Angiotensin I/II 1-6	RAAS; Others	Endocrinology/Hormones; Others
	Angiotensin I/II (1-6) 是由血管紧张素 I/II 肽转化而来，含有 1-6 个氨基酸的多肽。血管紧张素 I 被血管紧张素转换酶水解，形成具有生物活性的血管紧张素 II。血管紧张素 II 用于高血压、特发性膜性肾病和肾素-血管紧张素系统的研究。
TP1017L	Angiotensin II 5-valine TFA Angiotensin II 5-valine TFA(58-49-1 free base)	RAAS	Endocrinology/Hormones
	Angiotensin II 5-valine TFA 是血管紧张素受体的激动剂。
T7575L	[Sar1, Ile8]-Angiotensin II 3TFA [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))	Others	Others
	[Sar1, Ile8]-Angiotensin II 3TFA ([Sar1, Ile8]-Angiotensin II 3TFA (37827-06-8(free base))) 是一种对血管平滑肌具有多种作用的肽。
T7577	Angiotensin III, human, mouse 血管紧张素III,Angiotensin III, human, mouse(3TFA)	RAAS	Endocrinology/Hormones
	Angiotensin III, human, mouse (Angiotensin III, human, mouse(3TFA)) 是一种七肽，是血管紧张素 2 型受体 (AT2R) 激动剂，能够作用于 AT2R (IC50:0.648 nM)及 AT1R (IC50:21.1nM)。
TP2446L	Angiotensin amide acetate 血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base)	Others	Others
	Angiotensin amide acetate 是Angiotensin amide 的衍生物。Angiotensin amide 是一种八肽酰胺，可以通过血管收缩来提高血压。
T8560	Angiotensin II human acetate Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate,血管紧张素II	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Angiotensin II human acetate (DRVYIHPF acetate) 是血管收缩剂，是肾素/血管紧张素系统的主要生物活性肽，在调节人类血压中起着核心作用。它刺激交感神经刺激，增加醛固酮生物合成和肾脏活动。它诱导血管平滑肌细胞生长，也诱导细胞凋亡。它通过 LOX-1 依赖的氧化还原敏感途径诱导内皮细胞毛细血管形成。
T21708L	Angiotensin 1/2 + A (2 - 8) Acetate Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)	Others	Others
	Angiotensin 1/2 + A (2 - 8) Acetate 是一种血管收缩剂。
TP1295	Angiotensin I (human, mouse, rat) Angiotensin 1 Human,血管紧张素 1 (人)	Others	Others
	Angiotensin I (human, mouse, rat) 是血管紧张素Ⅱ的前体物质，在血管紧张素转化酶 (ACE) 的参与下裂解成血管紧张素Ⅱ。
T35834L	(Sar¹)-Angiotensin II acetate	RAAS	Endocrinology/Hormones
	(Sar¹)-Angiotensin II acetate 是血管紧张素 II 的类似物，是血管紧张素 AT1 受体的特异性激动剂。它与富含脑膜的颗粒结合，Kd 为 2.7 nM。它可以刺激胚胎鸡肌细胞中的蛋白质合成和细胞生长。
T7575L1	[Sar1, Ile8]-Angiotensin II acetate	RAAS	Endocrinology/Hormones
	[Sar1, Ile8]-Angiotensin II acetate 可激活 NADPH 和 NADH 氧化酶，并刺激血管平滑肌细胞中超氧阴离子的形成。 [Sar1, Ile8]-Angiotensin II acetate 对血管平滑肌有多种作用，包括正常动脉的收缩和培养细胞或病变血管的肥大或增生。
T7743	ANGIOTENSIN IV TFA(12676-15-2(free base))	RAAS	Endocrinology/Hormones
	ANGIOTENSIN IV TFA(12676-15-2(free base)) 是一种不太有效的血管紧张素 AT1 受体激动剂。
T22574L	Angiotensin 1/2 (5-7) acetate	RAAS	Endocrinology/Hormones
	Angiotensin 1/2 (5-7) acetate 是一种具有 H2N-Ile-His-Pro-OH 序列的肽。血管紧张素是一种寡肽，是一种激素和一种强大的双肽原。它来源于前体分子血管紧张素原，一种在肝脏中产生的血清球蛋白。它在肾素-血管紧张素系统中起重要作用。
T7663L	Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))	Others	Others
	Angiotensin 1/2 (1-9) TFA(34273-12-6(free base)) 含有从血管紧张素 I/II 肽转化而来的氨基酸 1-9。
T5824	Angiotensin II (3-8), human Angiotensin IV	RAAS	Endocrinology/Hormones
	Angiotensin II (3-8), human 是活性稍弱的血管紧张素AT1受体激动剂。
T35834	(Sar1)-Angiotensin II (Sar¹)-Angiotensin II
	The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
TP2370	Angiotensin pentapeptide Angiotensin II (4-8),(Des-1,2,3)angiotensin II
	Angiotensin pentapeptide is a peptide.
TP2446	Angiotensin amide Angiotensinamide,Hypertensine,Angiotensin,NSC 107678,NSC-107678
	Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.
T7575	[Sar1, Ile8]-Angiotensin II [Sar1, Ile8]-Angiotensin II(3TFA)	RAAS; Others	Endocrinology/Hormones; Others
	[Sar1, Ile8]-Angiotensin II 是一种在血管平滑肌细胞中有多种作用（如正常动脉的收缩，培养的细胞或病变血管的肥大或增生等）的多肽，。
TP1224	[Sar1, Ile8]-Angiotensin II TFA Angiotensin 2 TFA,AngiotensinII TFA
	[Sar1, Ile8]-Angiotensin II (TFA) is a peptide compound that exerts various effects on vascular smooth muscle. These effects include the contraction of normal arteries as well as the hypertrophy or hyperplasia of cultured cells or diseased vessels.
TP1017	Angiotensin II 5-valine Valine angiotensin II,5-L-Valine angiotensin II,血管紧张素 Ⅱ 5-缬氨酸
	ngiotensin II 5-valine is an angiotensin II analog which is an agonist at angiotensin receptors.
T10322	Angiotensin III	Others	Others
	Angiotensin III is an agonist of angiotensin 1 (AT1) and AT2 receptor.
T10322L	Angiotensin III TFA (12687-51-3 free base) Angiotensin III TFA	Others	Others
	Angiotensin III TFA is an agonist of angiotensin 1 (AT1) and AT2 receptor.
T31096	Crinia-angiotensin
	Crinia-angiotensin is an Angiotensin II-like undecapeptide from the skin of Australian frog Crinia georgiana.
T37495	Angiotensin (1-7) (acetate)
	Angiotensin 1-7 (Ang-(1-7)) acetate 是RAS中的一种内源性七肽，具备心脏保护作用，主要表现为对心肌细胞的抗炎与抗纤维化活性。该化合物能抑制纯化的犬ACE活性（IC50=0.65 μM），通过降低ACE活性并促进一氧化氮释放，作为血管舒张调节的局部协同因子。此外，Angiotensin 1-7 acetate 可阻止血管紧张素Ⅱ诱发的平滑肌细胞增殖和肥大，同时对内皮细胞表现出抗血管生成和生长抑制作用。
T38697	[Tyr(P)4] Angiotensin II
	[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.
T36622	Angiotensin I/II (1-6) (TFA)
	Angiotensin I/II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I/II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angiotensin I is then hydrolyzed by angiotensin-converting enzyme (ACE) to produce biologically active Angiotensin II. Angiotensin II has been extensively studied for its potential applications in the treatment of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Neph...
T22575	Angiotensin Fragment 1-7 (acetate)	Others	Others
	Angiotensin Fragment 1-7 is a type 1 angiotensin II receptor agonist. In the renin-angiotensin system, angiotensin I is cleaved by the angiotensin-converting enzyme to form angiotensin II, which has effects on fluid and electrolyte, as well as homeostasis
TP2464	Pentasarcosyl angiotensin II (Sar)5 aii
	Pentasarcosyl angiotensin II is a synthetic analog of angiotensin II.
T22574	Angiotensin 1/2 (5-7)	Others	Others
	Angiotensin 1/2 (5-7) is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays a
TP1522	Angiotensin II (5-8), human
	Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin II
T7663	Angiotensin 1/2 (1-9)	Others	Others
	Angiotensin 1/2 (1-9) 含有从血管紧张素 I/II 肽转化而来的氨基酸 1-9。
TP1609	Angiotensin II (1-4), human
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure. Angiotensin also potentiates the release of norepinephrine by a direct action on postganglionic sympathetic fibers.
T22573	Angiotensin 1/2 (2-7)	Others	Others
	Angiotensin I/II (2-7) is a peptide that contains the amino acids 2-7 and is converted from Angiotensin I/II peptide. Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure. Angiotensin also stimulates th
T22572	Angiotensin 1/2 (1-7) amide	Others	Others
	Angiotensin I/II (1-7) amide is a peptide analog to angiotensin II that is used as a vasopressor in the treatment of certain types of shock and circulatory collapse. Angiotensin I/II amide is an amide derivative of angiotensin II that is a powerful vasoco
T10323	Angiotensin II (3-8), human TFA	RAAS	Endocrinology/Hormones
	Angiotensin II (3-8), human (TFA) is an angiotensin AT1 receptor agonist with less activity.
TP1661	Angiotensin II (1-4), human TFA
	Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.
TP2220	Angiotensin 1/2 (1-8) amide	Others	Others
	Angiotensin 1/2 (1-8) amide (H2N-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-amide) is a peptide analog to angiotensin II that is used as a vasopressor agent in the treatment of certain types of shock and circulatory collapse. It is a potent vasoconstrictor and is us
TP2447	Angiotensin I, asn(1)-val(5)-gly(9)-
	Angiotensin I, asn(1)-val(5)-gly(9)- is isolated from the plasma of American eel, Anquilla rostrata.
T76169	Angiotensin-converting enzyme
	Angiotensin-converting enzyme (ACE)血管紧张素转换酶是一种二羧基肽酶，它将非活性的血管紧张素 I (Ang I) 转化为活性的 Ang II，并降解活性的缓激肽 (BK)。Angiotensin-converting enzyme 是一种有效的血管收缩剂，常用于生化研究。
TP1929L1	Saralasin acetate(34273-10-4 free base)	RAAS	Endocrinology/Hormones
	Saralasin acetate(34273-10-4 free base) 是一种非选择性血管紧张素 II 拮抗剂。
T74142	Angiotensin II human TFA
	Angiotensin II human (Angiotensin II) TFA 作为肾素/血管紧张素系统中关键的生物活性肽，扮演着血管收缩剂的角色并在调节人体血压中发挥中心作用。其主要通过与 G 蛋白偶联受体 (GPCRs)、血管紧张素 II 1型受体 (AT1R) 和血管紧张素 II 2型受体 (AT2R) 的相互作用来介导效应，包括刺激交感神经系统、增加醛固酮的生物合成和肾脏功能。此外，Angiotensin II human TFA 促进血管平滑肌细胞的生长和 I 型及 III 型胶原在成纤维细胞中的合成，导致血管壁与心肌增厚及纤维化，并诱导细胞凋亡。还通过LOX-1依赖的氧化还原敏感路径诱导内皮细胞中的毛细血管形成。
T83483	[Val4] Angiotensin III
	[Val4] Angiotensin III为血管紧张素III类肽，作为Gαq和βarr2反应的高效全激动剂，其pEC50值分别为8.31和8.44。
T76634	(Sar1,Ile4,8)-Angiotensin II
	(Sar1,Ile4,8)-Angiotensin II是一种对angiotensin II type 1 receptor (AT1R)具有功能选择性的激动剂，能增强胰岛素受体 (IR) 信号和糖原合成，同时还能促进Akt和GSK3α/β的磷酸化，这一过程被胰岛素刺激所增强。
T75975	Angiotensin III, human, mouse TFA
	Angiotensin III, human, mouse (TFA) 是一种血管紧张素。
T1484	Perindoprilat Perindoprilate,培哚普利	RAAS; MRP; AChR	Endocrinology/Hormones; Immunology/Inflammation; Neuroscience
	Perindoprilat (Perindoprilate) 是一种血管紧张素转换酶抑制剂。
T7510	Leucylarginylproline	RAAS	Endocrinology/Hormones
	Leucylarginylproline 是一种血管紧张素转换酶抑制剂，IC50=为0.27μM。
T2531	Eprosartan Mesylate SKF-108566J,甲磺酸依普罗沙坦	RAAS	Endocrinology/Hormones
	Eprosartan Mesylate (SKF-108566J) 是一种具有选择性、竞争性血管紧张素 II 受体拮抗剂，是具有口服活性的非肽。它结合血管紧张素 II 受体，在大鼠和人类肾上腺皮质膜中的IC50值分别为 9.2 nM 和 3.9 nM，可用作降压剂。
T7714	Temocapil	Tyrosinase	Proteases/Proteasome
	Temocapil 是一种酪氨酸激酶抑制剂。

化合物

Angiotensin I/II (1-5)

Cat.No: TP1528

Synonym: Angiotensin I/II 1-5

Target: RAAS, Others

Angiotensin (1-7)

Cat.No: T7339

Synonym: Ang-(1-7),Angiotensin 1-7,ASP-ARG-VAL-TYR-ILE-HIS-PRO

Target: RAAS, Endogenous Metabolite

Angiotensin I/II (1-6)

Cat.No: TP1579

Synonym: Angiotensin I/II 1-6

Target: RAAS, Others

Angiotensin II 5-valine TFA

Cat.No: TP1017L

Synonym: Angiotensin II 5-valine TFA(58-49-1 free base)

Target: RAAS

[Sar1, Ile8]-Angiotensin II 3TFA

Cat.No: T7575L

Synonym: [Sar1, Ile8]-Angiotensin II 3TFA(37827-06-8(free base))

Target: Others

Angiotensin III, human, mouse

Cat.No: T7577

Synonym: 血管紧张素III,Angiotensin III, human, mouse(3TFA)

Target: RAAS

Angiotensin amide acetate

Cat.No: TP2446L

Synonym: 血管紧张素胺,Angiotensin amide acetate(53-73-6 Free base)

Target: Others

Angiotensin II human acetate

Cat.No: T8560

Synonym: Ang II acetate,DRVYIHPF acetate,Angiotensin II acetate,血管紧张素II

Target: Apoptosis, RAAS

Angiotensin 1/2 + A (2 - 8) Acetate

Cat.No: T21708L

Synonym: Angiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)

Target: Others

Angiotensin I (human, mouse, rat)

Cat.No: TP1295

Synonym: Angiotensin 1 Human,血管紧张素 1 (人)

Target: Others

(Sar¹)-Angiotensin II acetate

Cat.No: T35834L

Target: RAAS

[Sar1, Ile8]-Angiotensin II acetate

Cat.No: T7575L1

Target: RAAS

ANGIOTENSIN IV TFA(12676-15-2(free base))

Cat.No: T7743

Target: RAAS

Angiotensin 1/2 (5-7) acetate

Cat.No: T22574L

Target: RAAS

Angiotensin 1/2 (1-9) TFA(34273-12-6(free base))

Cat.No: T7663L

Target: Others

Angiotensin II (3-8), human

Cat.No: T5824

Synonym: Angiotensin IV

Target: RAAS

(Sar1)-Angiotensin II

Cat.No: T35834

Synonym: (Sar¹)-Angiotensin II

Angiotensin pentapeptide

Cat.No: TP2370

Synonym: Angiotensin II (4-8),(Des-1,2,3)angiotensin II

Angiotensin amide

Cat.No: TP2446

Synonym: Angiotensinamide,Hypertensine,Angiotensin,NSC 107678,NSC-107678

[Sar1, Ile8]-Angiotensin II

Cat.No: T7575

Synonym: [Sar1, Ile8]-Angiotensin II(3TFA)

Target: RAAS, Others

[Sar1, Ile8]-Angiotensin II TFA

Cat.No: TP1224

Synonym: Angiotensin 2 TFA,AngiotensinII TFA

Angiotensin II 5-valine

Cat.No: TP1017

Synonym: Valine angiotensin II,5-L-Valine angiotensin II,血管紧张素 Ⅱ 5-缬氨酸

Angiotensin III

Cat.No: T10322

Target: Others

Angiotensin III TFA (12687-51-3 free base)

Cat.No: T10322L

Synonym: Angiotensin III TFA

Target: Others

Crinia-angiotensin

Cat.No: T31096

Angiotensin (1-7) (acetate)

Cat.No: T37495

[Tyr(P)4] Angiotensin II

Cat.No: T38697

Angiotensin I/II (1-6) (TFA)

Cat.No: T36622

Angiotensin Fragment 1-7 (acetate)

Cat.No: T22575

Target: Others

Pentasarcosyl angiotensin II

Cat.No: TP2464

Synonym: (Sar)5 aii

Angiotensin 1/2 (5-7)

Cat.No: T22574

Target: Others

Angiotensin II (5-8), human

Cat.No: TP1522

Angiotensin 1/2 (1-9)

Cat.No: T7663

Target: Others

Angiotensin II (1-4), human

Cat.No: TP1609

Angiotensin 1/2 (2-7)

Cat.No: T22573

Target: Others

Angiotensin 1/2 (1-7) amide

Cat.No: T22572

Target: Others

Angiotensin II (3-8), human TFA

Cat.No: T10323

Target: RAAS

Angiotensin II (1-4), human TFA

Cat.No: TP1661

Angiotensin 1/2 (1-8) amide

Cat.No: TP2220

Target: Others

Angiotensin I, asn(1)-val(5)-gly(9)-

Cat.No: TP2447

Angiotensin-converting enzyme

Cat.No: T76169

Saralasin acetate(34273-10-4 free base)

Cat.No: TP1929L1

Target: RAAS

Angiotensin II human TFA

Cat.No: T74142

[Val4] Angiotensin III

Cat.No: T83483

(Sar1,Ile4,8)-Angiotensin II

Cat.No: T76634

Angiotensin III, human, mouse TFA

Cat.No: T75975

Cat.No: T1484

Synonym: Perindoprilate,培哚普利

Target: RAAS, MRP, AChR

Leucylarginylproline

Cat.No: T7510

Target: RAAS

Eprosartan Mesylate

Cat.No: T2531

Synonym: SKF-108566J,甲磺酸依普罗沙坦

Target: RAAS

Cat.No: T7714

Target: Tyrosinase

Cat. No.	Product Name	Target	Signaling Pathways
T7040	Angiotensin II human DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II	Apoptosis; RAAS	Apoptosis; Endocrinology/Hormones
	Angiotensin II human (Ang II) 是一种生物活性肽，一种血管收缩剂。Angiotensin II 可以与 AT1R 和 AT2R 相互作用，调节人类血压，刺激交感神经，增加醛固酮生物合成和肾脏活动。
T5S0106	Peimisine 贝母辛,Ebeiensine	RAAS; AChR	Endocrinology/Hormones; Neuroscience
	Peimisine (Ebeiensine) 非竞争性拮抗气管平滑肌 M 受体，抑制 Ach 引起的平滑肌收缩。它兴奋 β 受体和拮抗内钙释放，促进一氧化氮释放，可舒张气管平滑肌，有平喘作用。
T13299	Vicenin 3 维采宁-3,维采宁 3	RAAS	Endocrinology/Hormones
	Vicenin 3来源于广金钱草的地上部分。Vicenin 3是血管紧张素转换酶抑制剂，IC50=46.91 μM。
T8270	Deserpidine 地舍平,Harmonyl	RAAS	Endocrinology/Hormones
	Deserpidine (Harmonyl) 是从 Rauwolfia canescens 的根中分离的生物碱。Deserpidine 与 Reserpine 相关。Deserpidine 是竞争性血管紧张素转化酶抑制剂，可以被用作抗高血压药以及镇定剂。Deserpidine 还减少了肾上腺皮质血管紧张素 II 诱导的醛固酮分泌。
T5796	Plantainoside D Isoplantamajoside,车前草苷D	RAAS; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
	Plantainoside D (Isoplantamajoside) 可以抑制 ACE ，IC50=2.17 mM。Plantainoside D 也是IKK-β抑制剂。
T21418	Lisinopril Linopril,赖诺普利,Zestril,Prinivil,Lisipril	RAAS	Endocrinology/Hormones
	Lisinopril (Prinivil) 是一种血管紧张素转化酶抑制剂，能够作用于高血压，充血性心力衰竭和心脏病等。
T3753	Sinapinic Acid Sinapic acid,芥子酸,Synapoic acid	Apoptosis; RAAS; Reactive Oxygen Species; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Endocrinology/Hormones; Immunology/Inflammation; Metabolism; NF-κB
	Sinapinic Acid (Synapoic acid) 是从 Hydnophytum formicarumJack. 根中分离到的酚类，是HDAC 抑制剂，对ACE-I 的活性也有抑制作用。它有抗肿瘤活性，诱导肿瘤细胞凋亡，具有抗氧化、抗糖尿病的作用。
T3851	Vicenin 2 Vicenin -2,维采宁 2,新西兰牡荆苷	RAAS	Endocrinology/Hormones
	Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂，IC50=43.83 μM。
T6627	Phosphoramidon Disodium Phosphoramidon Disodium Salt,磷酰胺二钠	RAAS; Neprilysin; Others	Endocrinology/Hormones; Metabolism; Others
	Phosphoramidon Disodium (Phosphoramidon Disodium Salt) Salt 是一种金属蛋白酶 (metalloprotease) 抑制剂。Phosphoramidon Disodium Salt 抑制内皮素转化酶 (ECE) ，中性肽内切酶 (NEP) 和血管紧张素转换酶 (ACE) 的IC50分别为 3.5 ，0.034 和 78 μM。
TN7109	Prosaikogenin G	RAAS	Endocrinology/Hormones
	Prosaikogenin G 是一种从柴胡的根中分离出的化合物，是 Saikosaponin d 在胃肠道中的衍生物。Prosaikogenin G 对 Angiotensin II 诱导的大鼠系膜细胞增殖具有明显的抑制作用，同时对肾脏有保护作用。
T6S0657	Isorhynchophylline IsoRhy,异钩藤碱,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline	Others	Others
	Isorhynchophylline (7-Isorhyncophylline) 是一种分离自钩藤中的生物碱类化合物，具有舒张血管、降血压、保护神经免于局部缺血造成损伤的作用。
TN2295	Vicenin-1 Vicenin -1	Antioxidant; Angiotensin-converting Enzyme (ACE)	Metabolism; oxidation-reduction
	Vicenin-1 (Vicenin -1) 是一种来自豆科植物胡卢巴种子中分离出来的类黄酮糖苷，具有强大的抗炎和抗氧化活性，抑制血管紧张素转换酶 (ACE) 。
T0522	Diammonium Glycyrrhizinate 甘草酸二铵,Glycyrrhizin	Dehydrogenase	Metabolism
	Diammonium Glycyrrhizinate (Glycyrrhizin) 是分离自甘草中的化合物，有抗炎作用。
TCS1704	Artemitin 艾黄素,Artemetin,Artemisetin,Erianthin	Antioxidant	oxidation-reduction
	Artemitin (Erianthin) 是一种存在于翼齿六棱菊中的天然黄酮，具有抗氧化、抗炎、抗病毒活性。
T2836	Isorhamnetin 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin	MEK; PI3K; Endogenous Metabolite	MAPK; Metabolism; PI3K/Akt/mTOR signaling
	Isorhamnetin (3-methylquercetin) 是从中草药沙棘中提取的一种类黄酮，可通过抑制MEK1和PI3K 来抑制皮肤癌。
T37298	Spinacine	Endogenous Metabolite	Metabolism
	Spinacine 是人内源性代谢产物。
TN4103	Ganoderic acid K
	Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities.
T38649	Lyciumin A
	Lyciumin A, a cyclic octapeptide, possesses inhibitory properties against proteases, renin, and angiotensin-converting enzyme. It holds potential for hypertension research.
T38481	Camellianin B
	Camellianin B, a flavonoid compound and metabolite of Camellianin A, exhibits antioxidant properties and acts as an angiotensin converting enzyme (ACE) inhibitor.
T19186	Aldosterone	Others	Others
	Aldosterone is the primary mineralocorticoid. Aldosterone is synthesized and secreted in response to renin-angiotensin system activation or high dietary potassium by the zona glomerulosa of the adrenal cortex.
T19911	Rescinnamine Anaprel,Apoterin S,Apoterin
	Rescinnamine is an inhibitor of angiotensin-converting enzyme. It also is a vinca alkaloid obtained from Rauwolfia serpentina and other species of Rauwolfia. It used as an antihypertensive drug.
TN2045	Pelargonidin-3-O-glucoside chloride	Others; Estrogen/progestogen Receptor	Endocrinology/Hormones; Others
	Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme inhibitory activities.
TN5645	Isomartynoside
	Isomartynoside has inhibition against the angiotensin converting enzyme (ACE) activities, the IC 50 value is 505±26.7μg/ml, it may have antihypertensive effect. Isomartynoside also shows obvious anti-fatigue activity.
TN1060	Ganoderol A 灵芝醇 A,灵芝醇A	Others	Others
	Ganoderol A has significant anti-inflammatory activity and protection against UVA damage. it has an inhibitory effect on angiotensin converting enzyme activity and cholesterol biosynthesis.
T38593	1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
	Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9, a quinolone alkaloid derived from Evodia rutaecarpa, is a potent antagonist of the angiotensin II receptor, displaying an IC50 value of 48.2 μM.
T81229	Safflor yellow B
	Safflor yellow B 通过抑制血管紧张素 II 介导的人脐静脉细胞损伤，调节 Bcl-2/p22 (phox) 表达，展现出神经保护作用。
TN2487	1,3,5,6-Tetrahydroxyxanthone	Others	Others
	1,3,5,6-Tetrahydroxyxanthone shows moderate hepatoprotective activity with EC(50) values of 160.2 +/- 0.6 microM against tacrine-induced cytotoxicity in HepG2 cells. It can inhibit angiotensin-I-converting-enzyme activity in a dose-dependent manner.
TN4860	Pueroside B	COX; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience
	Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A receptor (HMGR), cyclooxygenase-2 (COX2
TN4431	Leucosceptoside A	RAAS; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Endocrinology/Hormones
	Leucosceptoside A shows inhibitory activity against PKCalpha with the IC50 value of 19.0 microM; it also exhibits strong inhibitory capacity against α-glucosidase. Leucosceptoside A has antihypertensive effect, it shows angiotensin converting enzyme (ACE)
TN1061	Ganoderol B	Androgen Receptor	Endocrinology/Hormones
	Ganoderol B is a potent β ±-glucosidase and angiotensin-converting enzyme inhibitor, with an IC(50) of β ±-glucosidase is 119.8 uM. It may be useful in prostate cancer and benign prostatic hyperplasia (BPH) therapy through suppressing the function of andr
T79958	Isocrenatoside	Angiotensin-converting Enzyme (ACE)	Metabolism
	Isocrenatoside (compound 6)为环状八肽，具有ACE抑制活性。该化合物可通过乙醇提取Microtoena prainiana茎部分离纯化。研究显示，1 mg/mL浓度下，Isocrenatoside的ACE抑制效率高达99.3%。
T75697	1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone
	1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone，为喹诺酮类生物碱，作用为二酰基甘油酰基转移酶抑制剂与血管紧张素II受体阻断剂，其IC50值依次为20.1 μM与34.1 μM。此化合物亦展现对幽门螺杆菌的有效抗活性，MIC值达10 μg/mL。

天然产物

Angiotensin II human

Cat.No: T7040

Synonym: DRVYIHPF,Angiotensin II,Hypertensin II,血管紧张素Ⅱ,Ang II,血管紧张素II

Target: Apoptosis, RAAS

Cat.No: T5S0106

Synonym: 贝母辛,Ebeiensine

Target: RAAS, AChR

Cat.No: T13299

Synonym: 维采宁-3,维采宁 3

Target: RAAS

Cat.No: T8270

Synonym: 地舍平,Harmonyl

Target: RAAS

Plantainoside D

Cat.No: T5796

Synonym: Isoplantamajoside,车前草苷D

Target: RAAS, PKC

Cat.No: T21418

Synonym: Linopril,赖诺普利,Zestril,Prinivil,Lisipril

Target: RAAS

Cat.No: T3753

Synonym: Sinapic acid,芥子酸,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Cat.No: T3851

Synonym: Vicenin -2,维采宁 2,新西兰牡荆苷

Target: RAAS

Phosphoramidon Disodium

Cat.No: T6627

Synonym: Phosphoramidon Disodium Salt,磷酰胺二钠

Target: RAAS, Neprilysin, Others

Prosaikogenin G

Cat.No: TN7109

Target: RAAS

Isorhynchophylline

Cat.No: T6S0657

Synonym: IsoRhy,异钩藤碱,Isorhyncophylline,Isorhychophylline,7-Isorhyncophylline

Target: Others

Cat.No: TN2295

Synonym: Vicenin -1

Target: Antioxidant, Angiotensin-converting Enzyme (ACE)

Diammonium Glycyrrhizinate

Cat.No: T0522

Synonym: 甘草酸二铵,Glycyrrhizin

Target: Dehydrogenase

Cat.No: TCS1704

Synonym: 艾黄素,Artemetin,Artemisetin,Erianthin

Target: Antioxidant

Cat.No: T2836

Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin

Target: MEK, PI3K, Endogenous Metabolite

Cat.No: T37298

Target: Endogenous Metabolite

Ganoderic acid K

Cat.No: TN4103

Cat.No: T38649

Cat.No: T38481

Cat.No: T19186

Target: Others

Cat.No: T19911

Synonym: Anaprel,Apoterin S,Apoterin

Pelargonidin-3-O-glucoside chloride

Cat.No: TN2045

Target: Others, Estrogen/progestogen Receptor

Cat.No: TN5645

Cat.No: TN1060

Synonym: 灵芝醇 A,灵芝醇A

Target: Others

1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone

Cat.No: T38593

Safflor yellow B

Cat.No: T81229

1,3,5,6-Tetrahydroxyxanthone

Cat.No: TN2487

Target: Others

Cat.No: TN4860

Target: COX, PPAR

Leucosceptoside A

Cat.No: TN4431

Target: RAAS, PKC

Cat.No: TN1061

Target: Androgen Receptor

Cat.No: T79958

Target: Angiotensin-converting Enzyme (ACE)

1-Methyl-2-[(4Z,7Z)-4,7-tridecadienyl]-4(1H)-quinolone

Cat.No: T75697

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