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72

抑制剂 & 化合物

17

天然产物

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Cat. No. Product Name Target Signaling Pathways
T37819 Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (102-111) is a peptide fragment of brain-derived acidic fibroblast growth factor (aFGF). aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. It also shares sequence homology with the known neuropeptides neuromedin C , bombesin , neuromedin K , substance K , substance P , physalaemin, and eledoisin. aFGF (102-111) corresponds to amino acid residues 102-111 of the fulllength pept...
T37595 Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)

Brain-derived acidic fibroblast growth factor (brain-derived aFGF) (1-11) is a peptide fragment of brain-derived aFGF. Brain-derived aFGF is an angiogenic vascular endothelial cell mitogen produced in bovine brain that has sequence homology to interleukin-1. aFGF (1-11) corresponds to amino acid residues 1-11 of the full length peptide.
T50025 Lonazolac

PPAR DNA Damage/DNA Repair; Metabolism
Lonazolac 是一种具有抗炎特性的非甾体抗风湿剂。
T21572 Erythromycin A enol ether

Others Others
Erythromycin A enol ether 是大环内酯类抗生素红霉素A 的降解产物。
T0668 1-Aminohydantoin hydrochloride

Others Others
1-Aminohydantoin hydrochloride 是一种呋喃妥因在动物组织中的主要代谢物。它与组织蛋白共价结合,在微酸性条件下从组织中释放出来,与 2-硝基苯甲醛衍生形成 AHD 的硝基苯基衍生物可被检测。它可作为测定肉、奶等兽药残留的测定指标。
T37885 1-Dodecylimidazole

Antifungal Microbiology/Virology
1-Dodecylimidazole 是溶酶体活性洗涤剂。1-Dodecylimidazole 通过在溶酶体中的酸依赖性积累、溶酶体膜的破坏和半胱氨酸蛋白酶释放到细胞质中而导致细胞死亡。它显示出降胆固醇和广谱抗真菌活性。
T0312 Toluidine Blue

氯托洛宁,Blutene chloride

Others Others
Toluidine Blue (Blutene chloride) 是碱性噻嗪异染染料,能够高度亲和酸性组织成分,广泛应用于活体组织的重要染色及特殊染色。
T23173 Ponceau S

丽春红 S,Acid Red 112,Ponceau S Staining Solution

Others Others
Ponceau S (Ponceau S Staining Solution) 是一种常见的、用于 Western blot 的染色剂。它以酸性水溶液形式使用,能够与抗体-抗原结合兼容,将膜上的蛋白质染成红色。
T20362 Glutamyl-glutamic acid

Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid

Amino Acids and Derivatives Metabolism
Glutamyl-glutamic acid (Glu-glu) 是一些微球菌和节杆菌属菌的胞壁中的肽桥。
T19139 4-Nitrophenyl α-D-galactopyranoside

PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal

Others Others
4-Nitrophenyl α-D-galactopyranoside (PNP-alpha-D-Gal) 是 4-硝基苯基 (pNP) 糖吡喃糖苷的人工底物,可用于 α-半乳糖苷酶活性的检测。它用作底物能够显著增加 pNP 的释放量。
T19764 Trepibutone

AA-149,Colibil, Supacal,AA149,AA 149,曲匹布通

Others Others
Trepibutone (AA-149) 是一种酸性药物,具有不依赖于 pH 值的释放能力。
T4968 KHS 101

Microtubule Associated Cytoskeletal Signaling
KHS 101 是一种新型转化酸性卷曲螺旋蛋白 3 (TACC3) 的抑制剂。它是神经元分化的选择性诱导剂。
T11090L1 Aldoxorubicin hydrochloride

Aldoxorubicin hydrochloride (1361644-26-9 Free base)

Topoisomerase DNA Damage/DNA Repair
Aldoxorubicin hydrochloride 是 Doxorubicin (DNA 拓扑异构酶 II 抑制剂) 的白蛋白结合前药。Aldoxorubicin hydrochloride 在酸性条件下从白蛋白中释放出来。 Aldoxorubicin hydrochloride 显示出有效的抗肿瘤活性。
T40863 Bisdionin C

Antibacterial Microbiology/Virology
Bisdionin C 是一种有效的 GH18 chitinase 抑制剂,对 A. fumigatus ChiB1 的 IC50 为 0.2 μM。 Bisdionin C 抑制人巨噬细胞壳三糖苷酶 (HCHT, IC50 = 8.3 μM) 和酸性哺乳动物几丁质酶 (AMCase, IC50 = 3.4 μM)。
T8492 BO-264

Apoptosis; FGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
BO-264 是一种有口服活性的转化酸性卷曲螺旋 3 抑制剂,可特异性阻断 FGFR3-TACC3融合蛋白的功能。它诱导纺锤体检查点依赖的有丝分裂阻滞,DNA 损伤和细胞凋亡,具有广谱抗肿瘤活性。
T9592 OATD-01

Others Others
OATD-01 是一种壳三糖苷酶及酸性哺乳动物几丁质酶的高活性抑制剂,对CHIT1具有低纳摩尔活性 (hCHIT1,IC50=23 nM)。它在多个物种中显示出良好的药代动力学特征,在体内具有显著的抗纤维化活性,可用于研究肺纤维化。
T23280 Ruthenium Red

钌红,Ammoniated ruthenium oxychloride

Calcium Channel Membrane transporter/Ion channel; Metabolism
Ruthenium Red (Ammoniated ruthenium oxychloride) 是一种 L 型钙电流 (ICa) 阻断剂,是一种聚阳离子染料,广泛用于电子显微镜 (EM) 下细胞、组织和营养细菌的观察。它能与磷脂和脂肪酸反应强烈,并与酸性粘多糖结合。
T6929 Pantoprazole sodium

Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc

Apoptosis; Others; Proton pump; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others
Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂,是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,IC50为 6.8 μM。它可以改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
T1756 Ilaprazole sodium

IY-81149 sodium,艾普拉唑钠

Proton pump; TOPK MAPK; Membrane transporter/Ion channel
Ilaprazole sodium (IY-81149 sodium) 是一种具有口服活性质子泵抑制剂,以剂量依赖性方式不可逆地抑制 H+/K+-ATPase,在兔壁细胞制剂中的 IC50为 6 μM。它也是一种有效的 T 细胞起源蛋白激酶(TOPK)抑制剂,用于胃溃疡的研究。
TP2325L Endotoxin Inhibitor acetate

Endotoxin Inhibitor acetate(147396-10-9 free base)

Others Others
Endotoxin Inhibitor acetate(147396-10-9 free base) 对细菌生理活性有很强的阻断作用,从而产生具有二硫键和大量赖氨酸的抗菌毒素抑制剂序列。内毒素抑制剂醋酸盐在酸性条件下更可能发挥生理活性
TF0106 Cholesteryl Hemisuccinate Tris Salt

Apoptosis Apoptosis
Cholesteryl Hemisuccinate Tris Salt 是一种具有保肝和抗癌活性的酸性胆固醇酯,是一种含有柴胡皂苷-d的二棕榈酰磷脂酰胆碱脂质体中的膜稳定剂,可增强顺铂的抗癌功效。Cholesteryl hemisuccinate 具有抗肿瘤活性,抑制肿瘤生长,抑制对乙酰氨基酚 (AAP) 的肝毒性,预防 AAP 诱导的肝细胞凋亡。Cholesteryl hemisuccinate 可保护啮齿动物免受对乙酰氨基酚、阿霉素、四氯化碳、氯仿和半乳糖胺的毒性作用。
T70177 OAT-177

OAT-177 is a potent, selective, orally active acidic mammalian chitinase (AMCase) inhibitor.
T38850 AZD4721

RIST4721,AZD4721

AZD4721 (RIST4721) is the potent and orally active antagonist of acidic CXC chemokine receptor 2 ( CXCR2 ). AZD4721 has the potential for the research of inflammatory disease.
T27187 DK-1-49

DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.
T32293 JK-2 lithium

JK-2,JK2,JK 2

JK-2 is a hydrogen sulfide (H2S) donor. At acidic pH, it shows a greatly accelerated H2S release upon protonation-induced intramolecular cyclization.
T11289 Finafloxacin

Others Others
Finafloxacin, a fluoroquinolone antimicrobial agent from a new 8-cyano subclass, is most effective in slightly acidic environments (pH 5.0-6.0), a condition where other fluoroquinolones typically reduce in activity. It selectively targets bacterial type II topoisomerases, such as DNA gyrase and DNA topoisomerase IV, making it suitable for treating serious bacterial infections particularly in acidic contexts, including urinary tract infections (UTIs) and Helicobacter pylori infections.
T16272 Naproxen etemesil

LT-NS 001,MX 1094

PDE Metabolism
Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 μM, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.
T78621 Finafloxacin hydrochloride

Finafloxacin为一种氟喹诺酮类抗微生物剂,其抗菌活性在微酸性环境下最为显著。
T32287 Jegosapogenol A

Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D

Jegosapogenol A is a type of triterpenoid. Triterpenoids are terpene molecules containing six isoprene units. Barringtogenol C is a very weakly acidic compound (based on its pKa) and practically insoluble (in water). Barringtogenol C exists in tea. It can
T68890 Desvaleryl Valsartan

Desvaleryl valsartan is a potential impurity found in commercial preparations of the angiotensin II type 1 (AT1) receptor antagonist valsartan. It is a degradation product formed under acidic conditions.
T20098 NH2-PEG3-C2-Boc

Amino-PEG3-t-butyl ester

Amino-PEG3-t-butyl ester is a PEG derivative containing an amino group with the t-butyl protected carboxyl group. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
T25283 Cytochrome P450 2C9

Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase

Cytochrome P450 2C9 is a cytochrome P-450 subtype that possesses specificity for acidic xenobiotics. It oxidizes a wide range of important clinical drugs under the categories of nonsteroidal anti-inflammatory agents, anticoagulants, hypoglycemic agents, a
T24970 1'-Ethylascorbigen

1'-Ethylascorbigen releases ascorbic acid in acidic solution results in an increase in the cells' ability to produce PGE2 & LTB4. It has been shown to inhibit the growth of experimental murine tumors.
T76238 Zilganersen

Zilganersen (ION373) 为GFAP抑制剂,属于反义寡核苷酸类。适用于亚历山大病(AxD)的研究。
T81811 Methyl yellow

Dimethyl yellow,Solvent Yellow 2

Methyl yellow(Solvent Yellow 2)为pH指示剂,该化合物在pH低于4.0时显红色,高于4.0时转为黄色。
T76471 Lactoferricin, bovine

Lactoferricin, bovine 是一种铁结合糖蛋白,来源于牛乳铁蛋白的酸性水解。Lactoferricin, bovine 具有杀菌、抗真菌、抗寄生虫、抗肿瘤、抗病毒和免疫调节活性。
T38645 Acetyl-Hirudin (54-65) (sulfated)

Acetyl-Hirudin (54-65) (sulfated) directly binds to thrombin-rHCII(L444R) and hinders the interaction between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin, which stabilizes the complex.
T20860 Hydroxy-PEG12-t-butyl ester

Hydroxy-PEG12-t-butyl ester is a PEG derivative containing a hydroxyl group and a t-butyl ester. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Under acidic conditions, the t-butyl protected carbox
T36721 Dehydro Amlodipine (fumarate)

Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine. It is a degradation product formed during storage or when amlodipine is subjected to oxidative or acidic conditions or undergoes photo or electrochemical degradation.
T20915 Azido-PEG2-t-butyl ester

Azido-PEG2-t-butyl ester is a PEG derivative containing a t-butyl ester and an azide group. The hydrophilic PEG spacer increases solubility in aqueous media. Under acidic conditions, the t-butyl protected carboxyl group can be deprotected.
T72450 Influenza virus-IN-6

Influenza Virus Microbiology/Virology
Influenza virus-IN-6 (Compound 35) 是一种针对流感病毒聚合酶酸性蛋白亚基内切酶N端结构域(PAN)的高效抑制剂,展现出0.20 μM的IC50值。
T71872 Boc-8-aoc-oh

Boc-8-aoc-oh can be used as a PROTAC linker in the synthesis of PROTACs. Boc-8-aoc-oh is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T76168 Carboxypeptidase C

CarboxypeptidaseC为生化研究中常用的羧肽酶,专门用于切除多肽链羧基末端的赖氨酸、精氨酸和脯氨酸,同时也能处理包含中性、脂肪族、芳香族及酸性蛋白质氨基酸的肽链。
T70303 N-Boc-15-aminopentadecanoic acid

N-Boc-15-aminopentadecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T68842 Complestatin

Complestatin is a compound extracted from Streptomyces lavendulae mycelia; on acid hydrolysis yields D-4-hydroxyphenylglycine & D-3,5-dichloro-4-hydroxyphenylglycine & acidic chromophore; inhibits gp120-CD4 binding. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. It has a role as a metabolite, an antimicrobial agent and an anti-HIV-1 agent.
T63934 PAK4-IN-1

PAK4-IN-1 是一个选择性的、有效的、口服具有活力的 PAK4 抑制剂,在酸性和中性条件下都很稳定。PAK4-IN-1 在体内表现出良好的抗肿瘤作用。
T71906 Boc-12-Ado-OH

Boc-12-Ado-OH can be used as a PROTAC linker in the synthesis of PROTACs. Boc-12-Ado-OH is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.
T80427 Jingzhaotoxin-II

Sodium Channel Membrane transporter/Ion channel
Jingzhaotoxin-II是由32个氨基酸组成的神经毒素,包括两个酸性残基和两个碱性残基。该毒素能够抑制电压门控钠通道(VGSC),并在心肌细胞上明显减缓TTX抗性(TTX-R) VGSC的快速失活,其IC50值为0.26μM。
T80870 VE-PTP-IN-1

VE-PTP-IN-1 (compound 2) 为一种选择性VE-PTP抑制剂,呈弱酸性,涉及调控血管稳态及血管生成。
T39855 LysoTracker Red

LysoTracker Red DND-99

LysoTracker Red (LysoTracker Red DND-99) is a paraformaldehyde fixable probe that concentrates into acidic compartments of cells and tissues. LysoTracker Red is an indicator of cell death in a manner similar to other standard assays (Annexin, terminal dUTP nick end labeling, Nile blue sulfate, neutral red, and acridine orange). LysoTracker Red is a marker for late endosomes and lysosomes.

化合物

Brain-Derived Acidic Fibroblast Growth Factor (102-111) (bovine) (trifluoroacetate salt)
Cat.No: T37819
Synonym:
Target:
Brain-Derived Acidic Fibroblast Growth Factor (1-11) (bovine) (trifluoroacetate salt)
Cat.No: T37595
Synonym:
Target:
Lonazolac
Cat.No: T50025
Synonym:
Target: PPAR
Erythromycin A enol ether
Cat.No: T21572
Synonym:
Target: Others
1-Aminohydantoin hydrochloride
Cat.No: T0668
Synonym:
Target: Others
1-Dodecylimidazole
Cat.No: T37885
Synonym:
Target: Antifungal
Toluidine Blue
Cat.No: T0312
Synonym: 氯托洛宁,Blutene chloride
Target: Others
Ponceau S
Cat.No: T23173
Synonym: 丽春红 S,Acid Red 112,Ponceau S Staining Solution
Target: Others
Glutamyl-glutamic acid
Cat.No: T20362
Synonym: Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid
Target: Amino Acids and Derivatives
4-Nitrophenyl α-D-galactopyranoside
Cat.No: T19139
Synonym: PNP-alpha-D-Gal,4-硝基苯-α-D-吡喃半乳糖苷,PNP-α-D-Gal
Target: Others
Trepibutone
Cat.No: T19764
Synonym: AA-149,Colibil, Supacal,AA149,AA 149,曲匹布通
Target: Others
KHS 101
Cat.No: T4968
Synonym:
Target: Microtubule Associated
Aldoxorubicin hydrochloride
Cat.No: T11090L1
Synonym: Aldoxorubicin hydrochloride (1361644-26-9 Free base)
Target: Topoisomerase
Bisdionin C
Cat.No: T40863
Synonym:
Target: Antibacterial
BO-264
Cat.No: T8492
Synonym:
Target: Apoptosis, FGFR
OATD-01
Cat.No: T9592
Synonym:
Target: Others
Ruthenium Red
Cat.No: T23280
Synonym: 钌红,Ammoniated ruthenium oxychloride
Target: Calcium Channel
Pantoprazole sodium
Cat.No: T6929
Synonym: Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc
Target: Apoptosis, Others, Proton pump, HIF, Autophagy
Ilaprazole sodium
Cat.No: T1756
Synonym: IY-81149 sodium,艾普拉唑钠
Target: Proton pump, TOPK
Endotoxin Inhibitor acetate
Cat.No: TP2325L
Synonym: Endotoxin Inhibitor acetate(147396-10-9 free base)
Target: Others
Cholesteryl Hemisuccinate Tris Salt
Cat.No: TF0106
Synonym:
Target: Apoptosis
OAT-177
Cat.No: T70177
Synonym:
Target:
AZD4721
Cat.No: T38850
Synonym: RIST4721,AZD4721
Target:
DK-1-49
Cat.No: T27187
Synonym:
Target:
JK-2 lithium
Cat.No: T32293
Synonym: JK-2,JK2,JK 2
Target:
Finafloxacin
Cat.No: T11289
Synonym:
Target: Others
Naproxen etemesil
Cat.No: T16272
Synonym: LT-NS 001,MX 1094
Target: PDE
Finafloxacin hydrochloride
Cat.No: T78621
Synonym:
Target:
Jegosapogenol A
Cat.No: T32287
Synonym: Jegosapogenol,Giganteumgenin M,Proschiwalligenin PB1,Careyagenol A,Saniculagenin D
Target:
Desvaleryl Valsartan
Cat.No: T68890
Synonym:
Target:
NH2-PEG3-C2-Boc
Cat.No: T20098
Synonym: Amino-PEG3-t-butyl ester
Target:
Cytochrome P450 2C9
Cat.No: T25283
Synonym: Cyp2C9,Human cytochrome P450 2C9,Cytochrome P 450 2C9,S-Mephenytoin 4-hydroxylase
Target:
1'-Ethylascorbigen
Cat.No: T24970
Synonym:
Target:
Zilganersen
Cat.No: T76238
Synonym:
Target:
Methyl yellow
Cat.No: T81811
Synonym: Dimethyl yellow,Solvent Yellow 2
Target:
Lactoferricin, bovine
Cat.No: T76471
Synonym:
Target:
Acetyl-Hirudin (54-65) (sulfated)
Cat.No: T38645
Synonym:
Target:
Hydroxy-PEG12-t-butyl ester
Cat.No: T20860
Synonym:
Target:
Dehydro Amlodipine (fumarate)
Cat.No: T36721
Synonym:
Target:
Azido-PEG2-t-butyl ester
Cat.No: T20915
Synonym:
Target:
Influenza virus-IN-6
Cat.No: T72450
Synonym:
Target: Influenza Virus
Boc-8-aoc-oh
Cat.No: T71872
Synonym:
Target:
Carboxypeptidase C
Cat.No: T76168
Synonym:
Target:
N-Boc-15-aminopentadecanoic acid
Cat.No: T70303
Synonym:
Target:
Complestatin
Cat.No: T68842
Synonym:
Target:
PAK4-IN-1
Cat.No: T63934
Synonym:
Target:
Boc-12-Ado-OH
Cat.No: T71906
Synonym:
Target:
Jingzhaotoxin-II
Cat.No: T80427
Synonym:
Target: Sodium Channel
VE-PTP-IN-1
Cat.No: T80870
Synonym:
Target:
LysoTracker Red
Cat.No: T39855
Synonym: LysoTracker Red DND-99
Target:
Cat. No. Product Name Target Signaling Pathways
T18930 Bromothymol Blue

Others Others
Bromothymol Blue 是 pH 指示剂,在测定弱酸弱碱时使用,在酸性条件下为黄色,在碱性条件下为蓝色。
TN6699 DL-Malic acid

E 296,Hydroxybutanedioic acid

Endogenous Metabolite Metabolism
DL-Malic acid (Hydroxybutanedioic acid) 是一种存在于水果如苹果和梨中二羧酸。 它在许多酸味或酸味食物中起作用。
T5263 p-Hydroxymandelic acid

4-羟基扁桃酸,4-Hydroxymandelic acid

Others; Endogenous Metabolite Metabolism; Others
p-Hydroxymandelic acid (4-Hydroxymandelic acid) 是有价值的芳香类化学品,常用于生产药物和食品添加剂。
T0019 Betaine chloride

Betaine hydrochloride,盐酸甜菜碱

Others; Chloride channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism; Others
Betaine chloride (Betaine hydrochloride) 是一种天然化合物,在许多食物中能够发现,也是能够维持正常 DNA 甲基化模式的特性甲基供体。
T4784 (S)-(-)-Phenylethanol

(S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol

Others; Endogenous Metabolite Metabolism; Others
(S)-(-)-Phenylethanol ((-)-Methyl phenyl carbinol) 是内源性代谢产物的一种。
T2834 Nobiletin

Hexamethoxyflavone,川陈皮素,川皮苷

Apoptosis; MMP; Reactive Oxygen Species; ROR; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; NF-κB; Proteases/Proteasome
Nobiletin (Hexamethoxyflavone) 是一种来自柑橘皮的聚甲氧基黄酮,是RORs 激动剂,可改善记忆力丧失。它可降低分化的 C2C12 肌管中的ROS 水平,并具有抗炎,抗癌,抗血管生成,抗增殖,抗转移和诱导细胞凋亡作用。
T5082 Calcium 2-hydroxy-4-(methylthio)butanoate

羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt

Others; Endogenous Metabolite Metabolism; Others
Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) 是内源性代谢产物的一种。
Fr13883 3-Methoxyphenylacetic acid

Others Others
3-Methoxyphenylacetic acid 是 m-hydroxyphenylacetic (m-OHPAA) 的衍生物,茄形假丝酵母中的一种植物毒素。它可用于针对介氧菌根腐烂的毒素介导的生物测定法的开发。
T4773 3-Ethoxy-3-oxopropanoic acid

Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯

Others; Endogenous Metabolite Metabolism; Others
3-Ethoxy-3-oxopropanoic acid (Monoethyl malonic acid) 是内源性代谢产物的一种。
T2818 Methyl Vanillate

Reactive Oxygen Species; Wnt/beta-catenin; Endogenous Metabolite Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
Methyl vanillate 是一种枳椇属植物中的提取物,是Wnt/β-catenin 信号通路活化剂,是一种香草酸的甲酯。它具有抗氧化作用。
T4798 N-Acetyl-L-leucine

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-leucine 是内源性代谢产物的一种。
T4768 Diethyl oxalpropionate

草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE

Others; Endogenous Metabolite Metabolism; Others
Diethyl oxalpropionate (HYL 2-METHYL-3-OXOSUCCINATE) 是一种合成 PDMMLA 的中间体。其中 PDMMLA 的衍生物可用于纳米粒子的合成和研究。
T4837 Itaconic acid

methylene-butanedioicaci,衣康酸

Others; Endogenous Metabolite Metabolism; Others
Itaconic acid (methylene-butanedioicaci) 是聚合物,化学物质和燃料的合成前体。Itaconic acid 可由真菌合成。它也是巨噬细胞特异性代谢产物。它介导巨噬细胞代谢和腹膜肿瘤之间的串扰。
T7814L Alloxan

NSC 7169,NSC7169,NSC-7169

Alloxan is an acidic compound formed by the oxidation of URIC ACID.
T32740 Libramycin A

Libramycin A is a fat-soluble, weakly acidic substance extracted from Streptomyces.
T32329 Juzirine

Juzirine is a member of the class of benzylisoquinolines. Benzylisoquinolines are organic compounds containing an isoquinoline to which a benzyl group is attached. Juzirine, practically insoluble (in water), is a very weakly acidic compound (based on its
T73068 Mammea A/BA

Mammea A/BA 对克氏锥虫 (T. cruzi) 显示出有效抗性。通过诱导线粒体功能障碍、产生活性氧 (ROS)、DNA 片段化以及增加酸性液泡数量,Mammea A/BA 触发细胞死亡机制,包括细胞凋亡 (apoptosis)、细胞自噬 (autophagy) 和细胞坏死,对于南美锥虫病的研究具有潜在应用价值。

天然产物

Bromothymol Blue
Cat.No: T18930
Synonym:
Target: Others
DL-Malic acid
Cat.No: TN6699
Synonym: E 296,Hydroxybutanedioic acid
Target: Endogenous Metabolite
p-Hydroxymandelic acid
Cat.No: T5263
Synonym: 4-羟基扁桃酸,4-Hydroxymandelic acid
Target: Others, Endogenous Metabolite
Betaine chloride
Cat.No: T0019
Synonym: Betaine hydrochloride,盐酸甜菜碱
Target: Others, Chloride channel, Endogenous Metabolite
(S)-(-)-Phenylethanol
Cat.No: T4784
Synonym: (S)-(-)-1-Phenylethanol,右旋1-苯乙醇,(-)-Methyl phenyl carbinol,(S)-(-)-sec-Phenylethyl alcohol
Target: Others, Endogenous Metabolite
Nobiletin
Cat.No: T2834
Synonym: Hexamethoxyflavone,川陈皮素,川皮苷
Target: Apoptosis, MMP, Reactive Oxygen Species, ROR, Autophagy
Calcium 2-hydroxy-4-(methylthio)butanoate
Cat.No: T5082
Synonym: 羟基蛋氨酸钙,calcium hydroxymethionine,2-Hydroxy-4-(methylthio)butyric acid calcium salt
Target: Others, Endogenous Metabolite
3-Methoxyphenylacetic acid
Cat.No: Fr13883
Synonym:
Target: Others
3-Ethoxy-3-oxopropanoic acid
Cat.No: T4773
Synonym: Monoethyl malonic acid,Ethyl hydrogen malonate,丙二酸单乙酯
Target: Others, Endogenous Metabolite
Methyl Vanillate
Cat.No: T2818
Synonym:
Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite
N-Acetyl-L-leucine
Cat.No: T4798
Synonym:
Target: Others, Endogenous Metabolite
Diethyl oxalpropionate
Cat.No: T4768
Synonym: 草酰丙酸二乙酯,HYL 2-METHYL-3-OXOSUCCINATE
Target: Others, Endogenous Metabolite
Itaconic acid
Cat.No: T4837
Synonym: methylene-butanedioicaci,衣康酸
Target: Others, Endogenous Metabolite
Alloxan
Cat.No: T7814L
Synonym: NSC 7169,NSC7169,NSC-7169
Target:
Libramycin A
Cat.No: T32740
Synonym:
Target:
Juzirine
Cat.No: T32329
Synonym:
Target:
Mammea A/BA
Cat.No: T73068
Synonym:
Target:
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