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Search Results for " 虫草素 "

3

抑制剂 & 化合物

36

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T12135	Mycophenolic acid-d3 Mycophenolate-d3,Mycophenolate D3	Others; Antibacterial	Microbiology/Virology; Others
	Mycophenolic acid-d3 (Mycophenolate-d3) 是 Mycophenolic acid 的衍生物。Mycophenolic acid 是一种降低GTP 水平和损害RNA 聚合酶II (RNAP II)转录延伸的化合物，促进了近端位点的使用，能够逆转虫草素对选择性聚腺苷化的作用。
T32558	Lanosteryl acetate Lanosterol acetate
	Lanosteryl acetate is a bioactive chemical.
T32763	Lindelofine
	Lindelofine is a pyrrolizidine alkaloid.

化合物

Mycophenolic acid-d3

Cat.No: T12135

Synonym: Mycophenolate-d3,Mycophenolate D3

Target: Others, Antibacterial

Lanosteryl acetate

Cat.No: T32558

Synonym: Lanosterol acetate

Cat.No: T32763

Cat. No.	Product Name	Target	Signaling Pathways
T2993	Cordycepin 3'-Deoxyadenosine,虫草素	MMP; TNF; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Microbiology/Virology; Proteases/Proteasome
	Cordycepin (3'-Deoxyadenosine) 是一种核苷衍生物，在类风湿性关节炎滑膜成纤维细胞中，剂量依赖性抑制 IL-1β 诱导的 MMP-1和 MMP-3表达。它也抑制细菌的腺苷激酶从而抗结核分枝杆菌。
T2881	Crustecdysone Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素	Others; Caspase; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Metabolism; Others; Proteases/Proteasome
	Crustecdysone (Hydroxyecdysone) 是来源于露水草的一种蜕皮激素，可调节昆虫的蜕皮或蜕皮过程。它是 Ecdysone 的活性代谢物，通过 20E 核受体复合物 EcR-USP 抑制半胱天冬酶活性并诱导自噬，在心血管系统中具有调节或保护作用。
T7914	Acenaphthylene	Others	Others
	Acenaphthylene 是多环芳烃。其中多环芳烃是自然衍生于煤和焦油沉积物中，并由有机质的不完全燃烧得到。
T3890	Verbenalin Verbenalol β-D-glucopyranoside,马鞭草苷,Verbenaloside,Verbenalol glucoside,Cornin	Others	Others
	Verbenalin (Verbenaloside) 是马鞭草苷，具有抗炎、抗真菌、抗病毒等活性。它能减轻脑缺血再灌注损伤。它可用于前列腺炎的研究。
T3414	Morroniside 莫诺苷,奎宁树	Apoptosis; MMP; Pyroptosis	Apoptosis; Immunology/Inflammation; Proteases/Proteasome
	Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用，可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T3746	Dimethyl phthalate 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯	Others	Others
	Dimethyl phthalate (Fermine) 是一种邻苯二甲酸酯 (PAEs)，是一种已知的内分泌干扰物，也是一种普遍存在的污染物。它常作为增塑剂，赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。
T6981	1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid 1-甲基-6-氧代-1,6-二氢吡啶-3-羧酸,Nudifloric Acid	Others	Others
	1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (Nudifloric Acid) 是来源于冬虫夏草，能够靶向阻断 AP-1 介导的荧光素酶活性，具有抗炎活性。其中冬虫夏草具有抗氧化，抗癌，抗炎，抗糖尿病，抗肥胖，抗血管生成和抗伤害感受活动。
TJS0405	Lucidin NSC 30546,芦西定；卢西定,卢西定,亮黄素,Henine	Others	Others
	Lucidin (NSC-30546) 是茜草中的一种天然成分，可以诱导细菌和哺乳动物细胞的突变。
T5772	1F-fructofuranosylnystose	Others	Others
	1F-Fructofuranosylnystose 能够合成低聚果糖。其中低聚果糖对健康有益，是一种食品成分。
T4S1578	Nystose 1,1-Kestotetraose,耐斯糖,Fungitetraose,蔗果四糖	Others	Others
	Nystose (1,1-Kestotetraose) 是四糖，由两个果糖分子通过 β (1→2) 键与蔗糖的果糖基部分连接而成。
T5731	1-Kestose 蔗果三糖,1-蔗果三糖	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	1-Kestose 是低聚果糖成分，有效刺激了 Faecalibacterium prausnitzii 和 Bifidobacteria。它有抗羟基自由基的潜力。它可促进肠道内乳酸菌数量，影响微生物以及肠道和全身免疫反应。
T4775	Arachidic acid eicosanoic acid,Icosanoic Acid,花生酸	Others; Endogenous Metabolite	Metabolism; Others
	Arachidic acid (Icosanoic Acid) 是一种存在于所有哺乳动物细胞中的长链脂肪酸，通常酯化为膜磷脂，是人体组织中丰富的多不饱和脂肪酸之一。
T4237	Rubiadin-1-methyl ether Rubiadin 1-methyl ether,3-羟基-1-甲氧基-2-甲基蒽醌	Anti-infection; NF-κB	Microbiology/Virology; NF-κB
	Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) 是一种巴戟天中的蒽醌类化合物，能够抑制 NF-κB p65 的磷酸化和 IκBα 的降解以及减少 p65 的核转位，阻碍破骨细胞的骨吸收。
T36914	2-Hydroxyanthraquinone	Others	Others
	2-Hydroxyanthraquinone 是一种天然产物，显示出抗肿瘤和免疫抑制活性。
T6S1579	Monotropein 水晶兰苷,Monotropeine	Others	Others
	Monotropein (Monotropeine) 是从Morinda officinalis 中获得，能够抑制硫酸葡聚糖硫酸钠诱导的结肠炎小鼠模型中炎性因子的表达。
TN1213	2-(Hydroxymethyl)anthraquinone	Anti-infection	Microbiology/Virology
	2-(Hydroxymethyl)anthraquinone 是光可清除保护基团，在结构上可以阻碍性信息素释放。
T4744	5-HYDROXYINDOLE-3-ACETIC ACID 5-羟基吲哚-3-乙酸,5-HIAA	Others; Endogenous Metabolite	Metabolism; Others
	5-Hydroxyindole-3-acetic acid (5-HIAA) 是甲氧基肾上腺素或5-羟色胺的主要代谢产物，被用作神经内分泌肿瘤的生物标志物。它是血清素的分解产物，能够从尿液中排出。
T5S0636	Citric acid 柠檬酸,Citro,Citretten	Apoptosis; Others; Endogenous Metabolite; Antibacterial; Antibiotic	Apoptosis; Metabolism; Microbiology/Virology; Others
	Citric acid (Citro) 是柑橘类水果中发现的弱有机三羧酸。柠檬酸是食品添加剂和天然防腐剂。
TN1160	1,2,3,6-Tetragalloylglucose 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG	LDL; UGT	Metabolism
	1,2,3,6-Tetragalloylglucose (TeGG) 是 UDP-葡萄糖醛酸转移酶 1 家族成员，是多肽A1 的抑制剂(Ki:1.68 μM)。
TQ0188	Miquelianin 槲皮素-3-O-葡萄糖醛酸苷,Quercetin 3-glucuronide,Quercetin 3-O-glucuronide	stilbene oxidase; Endogenous Metabolite	Metabolism
	Miquelianin (Quercetin 3-glucuronide) 是槲皮素的代谢产物，属于类黄酮化合物。
TN3910	Ecdysone	Apoptosis; ATPase; Glucocorticoid Receptor; Potassium Channel; Sodium Channel; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; Membrane transporter/Ion channel; Metabolism
	Ecdysone 是存在于昆虫和草药中的主要类固醇激素，可以激活盐皮质激素受体并诱导细胞凋亡。Ecdysone 的活性代谢物 20-羟基蜕皮激素在协调发育过渡和体内稳态睡眠调节中起重要作用。
T7035	ANTHRAQUINONE-2-CARBOXYLIC ACID	IRAK; Syk	Angiogenesis; Immunology/Inflammation; NF-κB; Tyrosine Kinase/Adaptors
	Anthraquinone-2-carboxylic acid 从 Brazilian taheebo 中分离得到，具有抗炎、缓解疼痛的作用。
T6S1294	Nicotiflorin Nictoflorin,Kaempferol-3-O-Rutinoside,山奈酚-3-O-芸香糖苷,Nicotifloroside	Others	Others
	Nicotiflorin (Kaempferol-3-O-Rutinoside) 是一种黄酮苷，从传统中药Flos Carthami 中提取得到。它有抗糖化活性和神经保护作用。
T6000	Delta-Tocopherol (+)-DELTA-生育酚,D-DELTA-TOCOPHEROL	Endogenous Metabolite	Metabolism
	Delta-Tocopherol 是维生素 E 的异构体，具有抗氧化活性。
TN3616	Cedrelone	Apoptosis; MMP; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Cedrelone 是一种柠檬苦素类化合物，是一种吩嗪生物合成样结构域蛋白 (PBLD) 激活剂。Cedrelone 可诱导癌细胞凋亡 (apoptosis)。Cedrelone 是一种非常有效的细胞凋亡诱导剂，它能导致细胞周期停止。Cedrelone 具有杀虫活性，可抑制 P. saucia 的箭毒生长，并可抑制乳草蝽（Oncopeltus fasciatus）的蜕皮。Cedrelone具有抗肿瘤作用，对SMMC-7721、A-549、MCF-7 和 SW480 等癌细胞株具有显著的细胞毒性。
TN1330	7-O-Ethylmorroniside 7-乙氧基莫诺苷,7-O-ethyl-morroniside,7-氧乙基莫诺苷,金银花	Others	Others
	7-O-ethyl-morroniside is a natural product from Lonicera morrowii.
TN1331	7-O-Methyl morroniside 金银花,7-O-甲基莫诺甙	Others	Others
	7-O-Methyl morroniside is a natural product from Lonicera morrowii.
TN2500	1,5,15-Tri-O-methylmorindol	Others	Others
	1,5,15-Tri-O-methylmorindol has effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by TPA.
TN4956	Scandoside	NF-κB; MAPK	MAPK; NF-κB
	Scandoside exerts anti-inflammatory effect via suppressing NF-ÎºB and MAPK signaling pathways in LPS-induced RAW 264.7 macrophages.It also inhibits LDL-oxidation.
TN2762	2-Hydroxy-3-(hydroxymethyl)anthraquinone	Others	Others
	2-Hydroxy-3-(hydroxymethyl)anthraquinone 在 Hepa lclc7 细胞中表现出醌还原酶 (QR) 诱导活性，其 QR 活性加倍所需的浓度为 0.94 microM。
T40705	m-Tolualdehyde
	m-Tolualdehyde, also known as 3-Methylbenzaldehyde, is a chemical compound in the tolualdehyde family featuring a methyl substituent positioned at the 3-position. It finds application as a food additive.
T11555	Heptasaccharide Glc4Xyl3	Others	Others
	Heptasaccharide Glc4Xyl3 is a covalent inhibitor of endo-xyloglucanases. It used for the identification and analysis of diverse xyloglucan-active enzymes in nature.
TN1211	2-Hydroxy-3-methylanthraquinone	ERK; p38 MAPK; Caspase	Apoptosis; MAPK; Proteases/Proteasome
	2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction.
TN4538	Methyl beta-D-fructofuranoside	Others	Others
	Methyl beta-D-fructofuranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4538，CAS号为 13403-14-0。
TN1919	(+)-Medioresinol 梣皮树脂醇,皮树脂醇,Medioresinol	Beta Amyloid; ROS; Antifection	Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α²-secretase, it is a potentially valuable antiamyloidogenic agent for the prevent
TN2928	Pygenic acid A 3-Epicorosolic acid,脓毒酸A
	3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.3-Epicorosolic acid shows both potent α-glucosidase and pro

天然产物

Cat.No: T2993

Synonym: 3'-Deoxyadenosine,虫草素

Target: MMP, TNF, Antibacterial, Antibiotic, Autophagy

Cat.No: T2881

Synonym: Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,β-蜕皮甾酮,Hydroxyecdysone,羟基蜕皮激素

Target: Others, Caspase, Endogenous Metabolite, Autophagy

Cat.No: T7914

Target: Others

Cat.No: T3890

Synonym: Verbenalol β-D-glucopyranoside,马鞭草苷,Verbenaloside,Verbenalol glucoside,Cornin

Target: Others

Cat.No: T3414

Synonym: 莫诺苷,奎宁树

Target: Apoptosis, MMP, Pyroptosis

Dimethyl phthalate

Cat.No: T3746

Synonym: 邻苯二甲酸二甲酯,Solvanom,Avolin,Fermine,避蚊酯

Target: Others

1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid

Cat.No: T6981

Synonym: 1-甲基-6-氧代-1,6-二氢吡啶-3-羧酸,Nudifloric Acid

Target: Others

Cat.No: TJS0405

Synonym: NSC 30546,芦西定；卢西定,卢西定,亮黄素,Henine

Target: Others

1F-fructofuranosylnystose

Cat.No: T5772

Target: Others

Cat.No: T4S1578

Synonym: 1,1-Kestotetraose,耐斯糖,Fungitetraose,蔗果四糖

Target: Others

Cat.No: T5731

Synonym: 蔗果三糖,1-蔗果三糖

Target: Others, Endogenous Metabolite, Antibacterial

Cat.No: T4775

Synonym: eicosanoic acid,Icosanoic Acid,花生酸

Target: Others, Endogenous Metabolite

Rubiadin-1-methyl ether

Cat.No: T4237

Synonym: Rubiadin 1-methyl ether,3-羟基-1-甲氧基-2-甲基蒽醌

Target: Anti-infection, NF-κB

2-Hydroxyanthraquinone

Cat.No: T36914

Target: Others

Cat.No: T6S1579

Synonym: 水晶兰苷,Monotropeine

Target: Others

2-(Hydroxymethyl)anthraquinone

Cat.No: TN1213

Target: Anti-infection

5-HYDROXYINDOLE-3-ACETIC ACID

Cat.No: T4744

Synonym: 5-羟基吲哚-3-乙酸,5-HIAA

Target: Others, Endogenous Metabolite

Cat.No: T5S0636

Synonym: 柠檬酸,Citro,Citretten

Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic

1,2,3,6-Tetragalloylglucose

Cat.No: TN1160

Synonym: 1,2,3,6-Tetra-O-galloyl-β-D-glucose,1,2,3,6-四-O-没食子酰-Β-D-葡萄糖,TeGG

Target: LDL, UGT

Cat.No: TQ0188

Synonym: 槲皮素-3-O-葡萄糖醛酸苷,Quercetin 3-glucuronide,Quercetin 3-O-glucuronide

Target: stilbene oxidase, Endogenous Metabolite

Cat.No: TN3910

Target: Apoptosis, ATPase, Glucocorticoid Receptor, Potassium Channel, Sodium Channel, Endogenous Metabolite, Autophagy

ANTHRAQUINONE-2-CARBOXYLIC ACID

Cat.No: T7035

Target: IRAK, Syk

Cat.No: T6S1294

Synonym: Nictoflorin,Kaempferol-3-O-Rutinoside,山奈酚-3-O-芸香糖苷,Nicotifloroside

Target: Others

Delta-Tocopherol

Cat.No: T6000

Synonym: (+)-DELTA-生育酚,D-DELTA-TOCOPHEROL

Target: Endogenous Metabolite

Cat.No: TN3616

Target: Apoptosis, MMP, Antifection

7-O-Ethylmorroniside

Cat.No: TN1330

Synonym: 7-乙氧基莫诺苷,7-O-ethyl-morroniside,7-氧乙基莫诺苷,金银花

Target: Others

7-O-Methyl morroniside

Cat.No: TN1331

Synonym: 金银花,7-O-甲基莫诺甙

Target: Others

1,5,15-Tri-O-methylmorindol

Cat.No: TN2500

Target: Others

Cat.No: TN4956

Target: NF-κB, MAPK

2-Hydroxy-3-(hydroxymethyl)anthraquinone

Cat.No: TN2762

Target: Others

Cat.No: T40705

Heptasaccharide Glc4Xyl3

Cat.No: T11555

Target: Others

2-Hydroxy-3-methylanthraquinone

Cat.No: TN1211

Target: ERK, p38 MAPK, Caspase

Methyl beta-D-fructofuranoside

Cat.No: TN4538

Target: Others

(+)-Medioresinol

Cat.No: TN1919

Synonym: 梣皮树脂醇,皮树脂醇,Medioresinol

Target: Beta Amyloid, ROS, Antifection

Cat.No: TN2928

Synonym: 3-Epicorosolic acid,脓毒酸A

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