首页工具

登录

搜索结果

Search Results for " p50 "

15

抑制剂 & 化合物

4

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T13336	VTP50469	Apoptosis; Epigenetic Reader Domain; Histone Methyltransferase	Apoptosis; Chromatin/Epigenetic
	VTP50469 是一种高选择性和口服活性的Menin-MLL 相互作用抑制剂，具有有效的抗白血病活性，Ki 为 104 pM。
T24584	P505-15 Acetate PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate	Tyrosinase	Proteases/Proteasome
	P505-15 Acetate 是脾脏酪氨酸激酶的选择性抑制剂，通过抑制白细胞免疫功能和炎症起作用，导致关节炎评分降低和组织学损伤减轻。
T80132	CBP501 Affinity Peptide
	CBP501 Affinity Peptide为Chk激酶抑制剂，具有消除DNA损伤剂诱导的G2停滞作用，主要应用于癌症研究领域。
TP2164	TP508 TFA (121341-81-9 free base) TP508 TFA	Others	Others
	TP508 TFA is a nonproteolytic thrombin peptide. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates the production of NO in human endothelial cells. It activates endothelial cells and stem cells to revascularize and regenerates tissues.
TP1853	TP508
	TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibroblasts.TP508 (Chrysalin) is an investi
T62657	SHP504
	SHP504 是一种 SHP2 磷酸酶的抑制剂，能够作用于 SHP21–525 (IC50: 21 μM)。
T69846	VTP50469 mesylate
	VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.
T24736	RP5063 Hydrochloride RP-5063 HCl,RP 5063 HCl,RP 5063 Hydrochloride,RP-5063 Hydrochloride,RP5063 HCl
	RP5063 Hydrochloride is a modulator of multimodal serotonin receptors.
T13336L	VTP50469 fumarate	Others	Others
	VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.
T75763	TP508 TFA
	TP508 TFA为含23个氨基酸的非蛋白质水解凝血酶肽, 属凝血酶分子受体结合结构域部分。该化合物能激活内皮NO synthase(eNOS)，促进人内皮细胞内NO生成，进而通过激活内皮细胞及干细胞，促进血管及组织再生。
T69091	CBP501
	CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-specific phosphatase Cdc25C (cell division checkpoint 25 C); disruption of Cdc25C activity results in the inhibition of Cdc25C dephosphorylation of the mitotic cyclin-dependent kinase complex Cdc2/cyclin B, preventing entry into the mitotic phase of the cell cycle.
T72785	PRMT5:MEP50 PPI
	PRMT5:MEP50 PPI是一款新型的抑制剂，专门针对PRMT5:MEP50蛋白-蛋白相互作用，展现了抗肿瘤活性，并对肺癌及前列腺癌细胞具有显著的抗增殖效果。
T78846	EP12	Apoptosis	Apoptosis
	EP12是一种c-Myc抑制剂及c-MycG4稳定剂，能够诱导多发性骨髓瘤细胞的细胞凋亡(apoptosis)及DNA损伤，并通过干扰NF-κB信号通路破坏P65/P50的核转位，从而抑制多发性骨髓瘤的生长。
T38153	NF-κB Inhibitor (trifluoroacetate salt)
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α.1In this way, NF-κB inhibitor blocks gene expression that is regulated by NF-κB.2,3This peptide is commonly used to evaluate the role of NF-κB signaling in cellular responses.4,5
T37559	NF-κB Control
	NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids...

化合物

Cat.No: T13336

Target: Apoptosis, Epigenetic Reader Domain, Histone Methyltransferase

P505-15 Acetate

Cat.No: T24584

Synonym: PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate

Target: Tyrosinase

CBP501 Affinity Peptide

Cat.No: T80132

TP508 TFA (121341-81-9 free base)

Cat.No: TP2164

Synonym: TP508 TFA

Target: Others

Cat.No: TP1853

Cat.No: T62657

VTP50469 mesylate

Cat.No: T69846

RP5063 Hydrochloride

Cat.No: T24736

Synonym: RP-5063 HCl,RP 5063 HCl,RP 5063 Hydrochloride,RP-5063 Hydrochloride,RP5063 HCl

VTP50469 fumarate

Cat.No: T13336L

Target: Others

Cat.No: T75763

Cat.No: T69091

PRMT5:MEP50 PPI

Cat.No: T72785

Cat.No: T78846

Target: Apoptosis

NF-κB Inhibitor (trifluoroacetate salt)

Cat.No: T38153

Cat.No: T37559

Cat. No.	Product Name	Target	Signaling Pathways
TWS1977	Kamebakaurin 尾叶香茶菜丙素,Kamebakaurine	NF-κB	NF-κB
	Kamebakaurin (Kamebakaurine) 是一种提取自Isodon japonicus 中的天然产物，是一种NF-κB 的抑制剂，能够抑制 p50 的 DNA 结合活性。
T3012	Mangiferin Alpizarin,Chinomin,芒果,Hedysarid	Apoptosis; Others; NF-κB; Nrf2	Apoptosis; Immunology/Inflammation; NF-κB; Others
	Mangiferin (Hedysarid) 是一种Nrf2激活剂。它抑制NF-κB 亚基p65和p50的核移位，具有抗氧化、抗糖尿病、抗高尿酸血症、抗病毒、抗癌和抗炎活性。
TN3922	Effusanin E	PARP; NF-κB; Caspase; COX; Antifection	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
	Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-regulate COX-2 expression .
TN4635	Neoechinulin A	NADPH-oxidase; Beta Amyloid; ASK; IκB/IKK; p38 MAPK; TNF; NOS; NF-κB; COX; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; Neuroscience; NF-κB
	Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-ÎºB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regu

天然产物

Cat.No: TWS1977

Synonym: 尾叶香茶菜丙素,Kamebakaurine

Target: NF-κB

Cat.No: T3012

Synonym: Alpizarin,Chinomin,芒果,Hedysarid

Target: Apoptosis, Others, NF-κB, Nrf2

Cat.No: TN3922

Target: PARP, NF-κB, Caspase, COX, Antifection

Cat.No: TN4635

Target: NADPH-oxidase, Beta Amyloid, ASK, IκB/IKK, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼