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74

抑制剂 & 化合物

16

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9089	FTO-IN-1 UUN44923	Others	Others
	UUN44923 是脂肪及肥胖相关酶(FTO) 抑制剂(IC50<1 μM)。其中FTO-IN-1 (UUN44923) 可用于研究癌症。
T19658	Enflurane NSC115944,Ethrane,NSC-115944,恩氟烷,Efrane,NSC 115944	Others	Others
	Enflurane (Efrane) 是一种挥发性麻醉剂，是 Chara australis 高电导 Ca2+ 激活的 K+ 通道的有效抑制剂。安氟醚是通过顶空气相色谱-质谱法监测卤化挥发性麻醉剂的内标。它可以快速调整麻醉深度，而脉搏或呼吸频率几乎没有变化。
T11990	Meclofenamic acid 甲氯芬那酸,Meclofenamate	Others; Gap Junction Protein	Cytoskeletal Signaling; Others
	Meclofenamic acid (Meclofenamate) 是一种非特异性 gap-junction 阻滞剂和特异性脂肪量和肥胖相关 (FTO) 酶抑制剂。 Meclofenamic acid 具有抗炎活性。
T125029	Massarilactone B
	Massarilactone B 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125029，CAS号为 334022-96-7。
T35798	Massarigenin C
	Massarigenin C is a fungal metabolite that has been found inM. flavoroseaand has enzyme inhibitory activities.1,2Massarigenin C inhibits neuraminidasein vitro(IC50= 4.15 μM).2It is also an inhibitor of yeast α-glucosidase (IC50= 1.25 mM).1It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg.
T64336	Izilendustat	HIF/HIF Prolyl-Hydroxylase	Chromatin/Epigenetic; Metabolism
	tert-butyl 4-[[1-[(4-chlorophenyl)methyl]-3-hydroxy-2-oxopyridin-4-yl]methyl]piperazine-1-carboxylate 是一种脯氨酰羟化酶抑制剂。
T15177	DTNB Ellman’s Reagent,5,5'-二硫双(2-硝基苯甲酸)	Others	Others
	DTNB (Ellman’s Reagent) 是一种能够用于定量巯基数量或浓度的化学物质，可用于检测游离巯基。
T50050	2,3-dihydroxy-3-methylbutanoic acid	Others	Others
	2,3-dihydroxy-3-methylbutanoic acid 是支链氨基酸亮氨酸的天然代谢产物。它通过激活mTOR 信号通路发挥作用，促进新肌肉蛋白的合成，减少现有蛋白质的分解，从而增加肌肉质量，改善运动后的恢复。
T2408	Ostarine MK-2866,GTX-024,Enobosarm	Androgen Receptor	Endocrinology/Hormones
	Ostarine (MK-2866) 是一种具有合成代谢活性的非甾体药物。选择性雄激素受体调节剂 (SARM) GTx-024 旨在像睾酮一样发挥作用，从而促进和/或维持性欲、生育能力、前列腺生长以及肌肉生长和力量。模仿睾酮的作用，这种药物可以增加瘦体重，从而改善癌症恶病质高代谢状态下的肌肉萎缩。
T3685	SR9009 Stenabolic,REV-ERB Agonist II	Autophagy	Autophagy
	SR9009 (Stenabolic) 是一种REV-ERBα/β激动剂，可增加由 REV-ERBα/ERBβ 调节的基因的组成性抑制，IC50分别为 670 nM 和 800 nM。
T26583	AJS1669 AJS-1669,AJS 1669
	AJS1669, an activator of muscle glycogen synthase, improves glucose metabolism and reduces body fat mass in mice.
T15678	KZR-504	Proteasome	Proteases/Proteasome; Ubiquitination
	KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).
TP1964	Parathyroid hormone (1-34) (rat)
	Parathyroid hormone (PTH) receptor agonist. Increases serum PTH levels and bone mass in rats.
T31156	Cysteine hydrazide Cysteine,L-hydrazide
	Cysteine hydrazide is an enrichment tool for the mass spectrometric characterization of bacterial-free oligosaccharides.
T36217	19-hydroxy Cholesterol
	19-hydroxy Cholesterol is formed during metabolic oxidation of cholesterol. It has been used as an internal standard for the quantitative determination of sterols by mass spectroscopic analysis.[1]
T20584	Octanophenone Heptyl phenyl ketone,Caprylophenone
	Octanophenone can be analyzed by reverse phase (RP) HPLC method with simple conditions. The phosphoric acid needs to be replaced with formic acid for Mass-Spec (MS) compatible applications. For fast UPLC applications, smaller 3 µm particles columns is av
T69837	YKL-05-093
	YKL-05-093 is a alt inducible kinase (SIK) inhibitor. YKL-05-093 increases bone formation and bone mass.
T27736	KM10103 KM-10103,KM 10103
	KM10103 exhibits β-cell-protective activities against ER stress, which plays an important role in the decline in pancreatic β cell function and mass observed in type 2 diabetes.
T71769	D-Pyrohomoglutamic Acid
	D-Pyrohomoglutamic acid is a building block. It has been used in the synthesis of immunoproteasome low molecular mass polypeptide 2 (LMP2) subunit inhibitors and is a component of substance P peptide analogs.
T38912	Vicasinabin
	Vicasinabin, a potent agonist of cannabinoid receptor 2 (CB2), exhibits promising potential for researching chronic pain, atherosclerosis, regulation of bone mass, neuroinflammation, and related human diseases.
T63843	FTO-IN-5
	FTO-IN-5 是一种有效且选择性的脂肪量和肥胖相关蛋白（FTO）抑制剂。
T36065	N-Oleoyl-L-Serine
	Bone mass and shape is continuously remodeled by the concerted and balanced action of osteoblasts (bone forming cells) and osteoclasts (bone-resorbing cells). The endocannabinoid system plays an essential role in the maintenance of normal bone mass via signaling through the CB2 receptor. N-Oleoyl-L-serine is an endogenous lipid that has been reported to stimulate bone formation and to inhibit bone resorption.
T33789	Oleoyl proline N-Oleoyl-l-proline
	Oleoyl proline is an N-acyl amine that can be detected in bovine brain extracts and D. melanogaster larvae using mass spectrometry. In a preclinical model of pain, mice lacking fatty acid amide hydrolase (FAAH KO) had decreased N-oleoyl proline levels in
T27550	HMR-1426 HMR 1426,HMR1426
	HMR-1426 is gastric emptying inhibitor. HMR1426 shows an anorectic potential in rats and decreased body weight and fat mass. This was achieved solely by reducing food intake without influencing overall energy expenditure or behavior.
T31124	CW 008 CW-008,CW008
	CW 008 is an activator of the cAMP/PKA/CREB pathway. It promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells in vitro and increases bone mass and bone volume density in ovariectomized mice.
T38466	4-APC hydrobromide
	4-APC hydrobromide is a potent and specific aldehyde derivatization agent. It contains an aniline moiety that enables rapid and selective reaction with aliphatic aldehydes, as well as a quaternary ammonium group that enhances sensitivity in mass spectrometry (MS) analysis. By utilizing 4-APC hydrobromide, aldehydes can be detected with exceptional sensitivity and selectivity using MS.
T60994	FTO-IN-6
	FTO-IN-6是脂肪量和肥胖相关蛋白（FTO）的选择性抑制剂。
T73752	Glutarylcarnitine lithium
	Glutarylcarnitine lithium 丙二酸尿症和 I 型戊二酸尿症的重要诊断代谢物。
T78733	ZLD115
	ZLD115（化合物44）为FB23衍生的FTO抑制剂，作为抗白血病药物，对白血病细胞系展示抗增殖效果。
T75595	Loxosceles Bergeri Venom
	Loxosceles Bergeri Venom 是一种可以从Loxosceles Bergeri 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T75596	Loxosceles Pilosa Venom
	Loxosceles Pilosa Venom 是一种可以从Loxosceles Pilosa 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T61152	FTO-IN-8
	FTO-IN-8, also known as FTO-43, is an inhibitor of N6-methyladenosine demethylase FTO (fat mass- and obesity-associated protein). It exhibits an IC50 value of 5.5 μM and displays anti-cancer cell proliferative activity [1].
T36128	Tolmetin β-D-Glucuronide
	Tolmetin β-D-Glucuronide 与人血清白蛋白具有反应特性，可通过串联质谱法鉴定结合位点和反应机制。
T35243	YD2 YD-2,YD 2
	YD2 is a porphyrin sensitizer. YD2 is a useful material for making solar cell. Cosensitization of YD2-o-C8 with another organic dye enhances the performance of the device, leading to a measured power conversion efficiency of 12.3% under simulated air mass
T19945	N,N'-Carbonyldiimidazole 1,1'-Carbonyldiimidazole,N,N'-Carbonyldiimidazole,CDI Crosslinker	Others	Others
	N,N'-Carbonyldiimidazole 是一种生物交联剂，在质谱检测化合物纯度上有很大的应用。
T35419	τ-Fluvalinate
	τ-Fluvalinate is a pyrethroid acaricide.1It induces tail currents in Western honeybee (A. mellifera) voltage-gated sodium channels (AmNav1) expressed inXenopusoocytes (EC50= 60 nM). It also induces tail currents in honeybee parasitic Varroa mite (V. destructor) Nav1 channels (VdNav1) expressed inXenopusoocytes (EC50= 160 nM) with a faster tail current decay than that of AmNav1 channels. Topical application of τ-fluvalinate (2 μl) in combination with coumaphos , atrazine , 2,4-DMPF, chlorpyrifos ...
T37658	MitoP
	MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB . MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP. Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.
T74830	PDK-IN-1
	PDK-IN-1（compound 7o）是一种针对丙酮酸脱氢酶激酶（PDK）的抑制剂，其对PDK1和HSP90的IC50值分别为0.03和0.1μM。通过靶向PDH/PDK轴，PDK-IN-1能有效降低肿瘤质量。
T75823	GLP-2(rat) TFA
	GLP-2(rat) TFA为肠道生长因子，能刺激细胞增殖、抑制凋亡，且在大肠小肠切除术(MSBR)后，可提升残留小肠粘膜的品质与功能。
T60261	Clorprenaline
	Clorprenaline 是一种有效的β2-adrenergic 激动剂。Clorprenaline 促进动物肌肉生长并减少脂肪堆积。Clorprenaline 是一种潜在的新型瘦肉增效饲料添加剂。
T38012	SNOB 1 Reagent
	SNOB 1 Reagent is a biotinylated probe for detecting S-nitrosylated proteins in a single step. S-Nitrosylated binding (SNOB) proceeds rapidly on surface proteins or cell lysates under normal physiological conditions. Proteins tagged with SNOB 1 Reagent can be analyzed using avidin-linked probes (e.g., by immunoblot) or by mass spectrometry.
T75597	Loxosceles Spiniceps Venom
	Loxosceles Spiniceps Venom 是一种可以从Loxosceles Spiniceps 中获得的毒液。Loxosceles 蜘蛛的毒液是一种复杂的毒素混合物，富含蛋白质、糖蛋白和低分子质量多肽。目前已鉴定出几种蛋白类，包括类虾蛋白酶金属蛋白酶、低分子杀虫肽、抑制剂半胱氨酸结肽 (ICK) 和磷脂酶 D。其中独特的酶，鞘磷脂酶 D 负责坏死的发展。
T35785	N-Oleoyl Leucine
	N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro. N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO2 while slightly decreasing overall locomotor activity.
T13904	18:0 LYSO-PE Stearoyl lysophosphatidylethanolamine	Others	Others
	18:0 LYSO-PE 是一种诱导[Ca2+]i 增加的化合物，18:0 LYSO-PE 可用作电喷雾质谱（ESI-MS）/MS 进行脂质分析的磷脂（PL）标准。
T77087	Mipeginterferon alfa-2b
	Mipeginterferon alfa-2b 是一种干扰素IFNA2b 类似物。包括一个 N 末端和 10 个赖氨酸 N6 在内的 11 个氨基，平均被取代掉 5 个。Mipeginterferon alfa-2b 的相对分子质量为 40 kDa。
T37209	5-hydroxy Flunixin
	5-hydroxy Flunixin is a metabolite of the COX inhibitor flunixin .1 1.Daeseleire, E., Mortier, L., De Ruyck, H., et al.Determination of flunixin and ketoprofen in milk by liquid chromatography-tandem mass spectrometryAnal. Chim. Acta488(1)25-34(2003)
T36223	MitoA
	MitoA is a ratiometric mass spectrometry probe that can be used for assessing changes in H2S within mitochondria in vivo. MitoA contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its aryl azide moiety selectively reacts with H2S to produce an amine product, MitoN. Quantifying the MitoN/MitoA ratio by LC-MS/MS reflects the mitochondrial matrix H2S concentration. In a mouse model of acute myocardial infarction with MitoA administered prior to ischem...
T37311	Dichloroiodomethane
	Dichloroiodomethane is a natural compound in human beings[1]. [1]. Lalith K. Silva, et al. Quantification of Dichloroiodomethane and Bromochloroiodomethane in Human Blood by Solid-Phase Microextraction Coupled with Gas Chromatography-High-Resolution Mass Spectrometry. Journal of Analytical Toxicology, Volume 30, Issue 9, November-December 2006, Pages 670-678.
T74736	2MD
	2MD是一种口服活性维生素D类似物，能刺激骨膜骨形成并减少小梁骨吸收，从而恢复小梁和皮质骨的质量与强度。在非人灵长类动物研究中，2MD还可以调节(IOP)相关基因，降低眼压。
T36731	Cholesteryl Heptadecanoate
	Cholesteryl heptadecanoate is a cholesterol ester (CE) formed by the condensation of cholesterol with heptadecanoic acid, a C-17 saturated fatty acid that does not occur in any natural animal or vegetable fat at high concentrations. As such, it is commonly used as an internal standard for the quantification of cholesterol esters by GC- or LC-mass spectrometry. CEs are major constituents of lipoprotein particles carried in blood and accumulate in the fatty acid lesions of atherosclerotic plaques....

化合物

Cat.No: T9089

Synonym: UUN44923

Target: Others

Cat.No: T19658

Synonym: NSC115944,Ethrane,NSC-115944,恩氟烷,Efrane,NSC 115944

Target: Others

Meclofenamic acid

Cat.No: T11990

Synonym: 甲氯芬那酸,Meclofenamate

Target: Others, Gap Junction Protein

Massarilactone B

Cat.No: T125029

Massarigenin C

Cat.No: T35798

Cat.No: T64336

Target: HIF/HIF Prolyl-Hydroxylase

Cat.No: T15177

Synonym: Ellman’s Reagent,5,5'-二硫双(2-硝基苯甲酸)

Target: Others

2,3-dihydroxy-3-methylbutanoic acid

Cat.No: T50050

Target: Others

Cat.No: T2408

Synonym: MK-2866,GTX-024,Enobosarm

Target: Androgen Receptor

Cat.No: T3685

Synonym: Stenabolic,REV-ERB Agonist II

Target: Autophagy

Cat.No: T26583

Synonym: AJS-1669,AJS 1669

Cat.No: T15678

Target: Proteasome

Parathyroid hormone (1-34) (rat)

Cat.No: TP1964

Cysteine hydrazide

Cat.No: T31156

Synonym: Cysteine,L-hydrazide

19-hydroxy Cholesterol

Cat.No: T36217

Cat.No: T20584

Synonym: Heptyl phenyl ketone,Caprylophenone

Cat.No: T69837

Cat.No: T27736

Synonym: KM-10103,KM 10103

D-Pyrohomoglutamic Acid

Cat.No: T71769

Cat.No: T38912

Cat.No: T63843

N-Oleoyl-L-Serine

Cat.No: T36065

Cat.No: T33789

Synonym: N-Oleoyl-l-proline

Cat.No: T27550

Synonym: HMR 1426,HMR1426

Cat.No: T31124

Synonym: CW-008,CW008

4-APC hydrobromide

Cat.No: T38466

Cat.No: T60994

Glutarylcarnitine lithium

Cat.No: T73752

Cat.No: T78733

Loxosceles Bergeri Venom

Cat.No: T75595

Loxosceles Pilosa Venom

Cat.No: T75596

Cat.No: T61152

Tolmetin β-D-Glucuronide

Cat.No: T36128

Cat.No: T35243

Synonym: YD-2,YD 2

N,N'-Carbonyldiimidazole

Cat.No: T19945

Synonym: 1,1'-Carbonyldiimidazole,N,N'-Carbonyldiimidazole,CDI Crosslinker

Target: Others

Cat.No: T35419

Cat.No: T37658

Cat.No: T74830

Cat.No: T75823

Cat.No: T60261

Cat.No: T38012

Loxosceles Spiniceps Venom

Cat.No: T75597

N-Oleoyl Leucine

Cat.No: T35785

Cat.No: T13904

Synonym: Stearoyl lysophosphatidylethanolamine

Target: Others

Mipeginterferon alfa-2b

Cat.No: T77087

5-hydroxy Flunixin

Cat.No: T37209

Cat.No: T36223

Dichloroiodomethane

Cat.No: T37311

Cat.No: T74736

Cholesteryl Heptadecanoate

Cat.No: T36731

Cat. No.	Product Name	Target	Signaling Pathways
TN4503	Massonianoside B	Others	Others
	Massonianoside B shows potent antioxidant activity.
TN4504	Massoniresinol	Others	Others
	Massoniresinol是一种天然产物，属于八角科八角属，其产品编号为 TN4504，CAS号为 96087-10-4。Massoniresinol可用作对照参考。
T72732	Massarilactone H
	Massarilactone H 是一种聚酮化合物，是神经氨酸酶抑制剂，IC50值为 8.18 µM。
TN6779	Clausine E	Others	Others
	Clausine E 是脂肪量和肥胖相关蛋白 (FTO) 脱甲基酶活性的抑制剂。 Clausine E 与 FTO 的结合是由正熵和负焓变化驱动的。
T13768	(+)-Medicarpin	Estrogen/progestogen Receptor	Endocrinology/Hormones
	(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β.
TN1918	Medicarpin 美迪紫檀素	Apoptosis; BCL; ROS; JNK	Apoptosis; Immunology/Inflammation; MAPK
	Medicarpin 是从紫花苜蓿中分离出的一种类黄酮。它通过调节 P-gp 介导的药物外流，诱导白血病 P388 细胞凋亡并克服多药耐药性。
T19340	Glutarylcarnitine O-glutaroyl-L-carnitine	Endogenous Metabolite	Metabolism
	Glutarylcarnitine (O-glutaroyl-L-carnitine) 是大多数串联质谱新生儿筛查计划中监测的丙二酸尿症和谷草酸尿症 I 型的诊断代谢物。
T2818	Methyl Vanillate	Reactive Oxygen Species; Wnt/beta-catenin; Endogenous Metabolite	Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
	Methyl vanillate 是一种枳椇属植物中的提取物，是Wnt/β-catenin 信号通路活化剂，是一种香草酸的甲酯。它具有抗氧化作用。
T4816	6-Hydroxynicotinic acid 6-Hydroxypyridine-3-carboxylic acid,6-羟基烟酸,2-Hydroxy-5-pyridinecarboxylic acid	Others; Endogenous Metabolite	Metabolism; Others
	6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) 用于核磁共振波谱或气相色谱-质谱法诊断尿路感染中的铜绿假单胞菌。在引起尿液感染的常见细菌中，只有铜绿假单胞菌从烟酸中产生6-羟基烟酸。
T5294	(S)-Leucic acid L-alpha-羟基异己酸,L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-2-羟基-4-甲基戊酸,(S)-(−)-2-Hydroxyisocaproic acid	Others; Endogenous Metabolite	Metabolism; Others
	(S)-Leucic acid (Hydroxyisocaproic acid) 是氨基酸代谢物。
T13265	Urolithin B 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮	ERK; NF-κB; Akt; Endogenous Metabolite; JNK; AMPK	Chromatin/Epigenetic; Cytoskeletal Signaling; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Urolithin B 是一种 ellagitannins 的肠道微生物代谢产物，具有抗炎和抗氧化作用。它也是骨骼肌质量的调节因子，通过减少 IκBα 的磷酸化和降解来抑制 NF-κB 活性，并抑制 JNK、ERK 和 Akt 的磷酸化，并增强 AMPK 的磷酸化。
T25634	Lasiocarpine N-oxide 4-21-00-02054 (Beilstein Handbook Reference)
	Lasiocarpine N-oxide is a natural compound found to be higher in many tea bags, herbal drugs and honey by mass spectrometry.
T19236	Cholesteryl behenate Cholesteryl docosanoate,Cholesterol behenate,胆固醇山萮酸酯	Others	Others
	Cholesteryl behenate is a standard in electrospray ionization tandem mass spectrometry for the analysis of cholesteryl esters and cholesterol.
T83916	Cytogenin
	Cytogenin（一种源自S. eurocidicum的香豆素衍生物）具有多种生物活性。在每日给药25 mg/kg剂量下，能减轻Ehrlich鼠自发性腺癌模型的肿瘤重量。在体内，Cytogenin（每日30和100 mg/kg）可减少链脲佐菌素诱导的体重下降和血浆葡萄糖水平上升，以及小鼠糖尿病模型中巨噬细胞胰腺浸润。同时，在每日100 mg/kg的剂量下，能降低小鼠巨噬细胞中zymosan和LPS诱导的一氧化氮产生，及LPS诱导的Il-6水平增加。
T37770	Taurohyodeoxycholic acid
	Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid .1THDCA decreases the size and weight of human gallstonesin vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats.2Co-administration of THDCA with taurochenodeoxycholic acid prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats.3THDCA also reduces myeloperoxidase activity, expressi...
T36915	21-Deoxycortisol
	21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. 1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive...

天然产物

Massonianoside B

Cat.No: TN4503

Target: Others

Massoniresinol

Cat.No: TN4504

Target: Others

Massarilactone H

Cat.No: T72732

Cat.No: TN6779

Target: Others

Cat.No: T13768

Target: Estrogen/progestogen Receptor

Cat.No: TN1918

Synonym: 美迪紫檀素

Target: Apoptosis, BCL, ROS, JNK

Glutarylcarnitine

Cat.No: T19340

Synonym: O-glutaroyl-L-carnitine

Target: Endogenous Metabolite

Methyl Vanillate

Cat.No: T2818

Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite

6-Hydroxynicotinic acid

Cat.No: T4816

Synonym: 6-Hydroxypyridine-3-carboxylic acid,6-羟基烟酸,2-Hydroxy-5-pyridinecarboxylic acid

Target: Others, Endogenous Metabolite

(S)-Leucic acid

Cat.No: T5294

Synonym: L-alpha-羟基异己酸,L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-2-羟基-4-甲基戊酸,(S)-(−)-2-Hydroxyisocaproic acid

Target: Others, Endogenous Metabolite

Cat.No: T13265

Synonym: 尿石素B,3-羟基-6H-苯并[C]苯并吡喃-6-酮

Target: ERK, NF-κB, Akt, Endogenous Metabolite, JNK, AMPK

Lasiocarpine N-oxide

Cat.No: T25634

Synonym: 4-21-00-02054 (Beilstein Handbook Reference)

Cholesteryl behenate

Cat.No: T19236

Synonym: Cholesteryl docosanoate,Cholesterol behenate,胆固醇山萮酸酯

Target: Others

Cat.No: T83916

Taurohyodeoxycholic acid

Cat.No: T37770

21-Deoxycortisol

Cat.No: T36915

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