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121

抑制剂 & 化合物

17

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T37518	Diphenyl disulfide Phenyl disulfide	Apoptosis; BCL; Endogenous Metabolite	Apoptosis; Metabolism
	Diphenyl disulfide (Phenyl disulfide) 在乳腺癌细胞系中显示出抗癌活性。Diphenyl disulfide 通过Bax 蛋白水解活化和伴随的自噬来诱导并增强乳腺癌细胞的凋亡。Diphenyl disulfide 以剂量依赖性方式抑制细胞增殖和活力，并减少集落形成。Diphenyl disulfide 可用来治疗乳腺癌。
T19780	2,2′-Dipyridyl disulfide 2,2'-Dipyridyl disulfide,OPSS,2,2'-二硫二吡啶,Aldrithiol 2,Orthopyridyl disulfide	Others	Others
	2,2′-Dipyridyl disulfide (Aldrithiol 2) 是肽化学中的常用试剂，是测定巯基的有用试剂，常用于氧化还原缩合以形成肽键或用于偶联反应以形成二硫键连接的异二聚体。
T31479	Diisopropyl xanthogen disulfide NSC1339,NSC 1339,Isopropylxanthic disulfide,二硫化二异丙基黄原酸酯,NSC-1339	Others	Others
	Diisopropyl xanthogen disulfide (NSC-1339) 可用于合成与钼辅因子相关的金属络合物的前配体。
T20062	Thiamine disulfide 二硫化硫胺,TDS,Daiomin,Algoneurina	HIV Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Thiamine disulfide (Algoneurina) 是一种存在于食物中的维生素，可作为膳食补充剂和药物生产。它还充当许多中枢代谢酶的辅助因子。
TP1033L	Transdermal Peptide Disulfide Acetate TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)	ATPase	Membrane transporter/Ion channel
	Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) 是一种 11 个氨基酸的肽，与 Na+/K+-ATPase β 亚基 (ATP1B1) 结合，主要与 ATP1B1 的 C 端相互作用。透皮肽可以增强许多大分子的透皮传递。透皮肽 TD 1 酰胺是一种新型肽，旨在增强透皮药物传递。
T34853	Thiola-cysteine disulfide Mercaptopropionylglycine-cysteine disulfide
	Thiola-cysteine disulfide is a urinary metabolite of thiola.
T21089	Nitrophenide 3,3'-Dinitrodiphenyl disulfide,3,3'-二硝基二苯二硫醚	Dehydrogenase	Metabolism
	Nitrophenide (3,3'-Dinitrodiphenyl disulfide) 抑制甘露醇-1-磷酸脱氢酶 (M1PDH)，该酶催化甘露醇循环中的酶促步骤。 Nitrophenide 可用作抗球虫剂。
T38312	L-Cysteine-glutathione disulfide
	L-Cysteine-glutathione disulfide, a glutathione derivative endogenous to mammalian cells, is comprised of the oxidized form of free glutathione tripeptide linked via a disulfide bond to L-cysteine. It has been shown to protect mice against acetaminophen-induced hepatotoxicity.
T71049	Famotidine disulfide
	Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease.
T37767	Transdermal Peptide Disulfide TFA
	Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA), an 11-amino acid peptide, specifically binds to the Na+/K+-ATPase beta-subunit (ATP1B1), predominantly interacting with its C-terminus. This compound is capable of enhancing the transdermal delivery of various macromolecules[1].
T19968	Xylyl disulfide
	Xylyl disulfide is an agent of biochemical.
T83633	1-N-Methyl-4-mercaptohistidine disulfide	Others	Others
	1-N-Methyl-4-mercaptohistidine disulfide 是一种潜在的杜氏菌叶绿体偶联因子1氧化还原调节剂，是氧化形式的卵硫醇A，抑制光触发的CF1 ATP酶活性。
T71161	Thiorphan disulfide
	Thiorphan disulfide is an impurity of Racecadotril -- an antidiarrheal and enkephalinase inhibitor that reduces the amount of water and electrolytes absorbed into the intestine.
T0054	Disulfiram 双硫伦,Tetraethylthiuram disulfide,双硫仑,NSC 190940,TETD	Dehydrogenase; Interleukin; Pyroptosis	Apoptosis; Immunology/Inflammation; Metabolism
	Disulfiram (TETD) 是一种乙醛脱氢酶 ALDH 的抑制剂，抑制 hALDH1 和 hALDH2 (IC50=0.15/1.45 μM)，具有特异性。Disulfiram 对酒精产生急性敏感性，还可以抑制 GSDMD 孔形成。
T20512	Captopril disulfide SQ14,551,SQ 14,551,SQ-14,551
	Captopril disulfide, a metabolite of Captopril, is a new antihypertensive agent.
T19986	Molybdenum disulfide Moly Powder B,Molykote Microsize Powder,T-Powder,Molysulfide,Natural molybdenite
	Molybdenum disulfide is the inorganic compound with the formula MoS2. Molybdenum disulfide is insoluble in water and dilutes acids. This black crystalline sulfide of molybdenum occurs as the mineral molybdenite.
TP1033	Transdermal Peptide Disulfide Transdermal Peptide,TD 1 (peptide)
	Transdermal Peptide (TD 1 peptide) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Pep
T14016	2-Hydroxyethyl disulfide mono-tosylate	Others	Others
	2-Hydroxyethyl disulfide mono-tosylate is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T14663	Bis-Tos-(2-hydroxyethyl disulfide)	Others	Others
	Bis-Tos-(2-hydroxyethyl disulfide) is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].
T26823	Bisbutytiamine Bisbutitiamine,Bisbutiamine,o-Butyrylthiamine disulfide
	Bisbutytiamine, a dimer of butytiamine, is a potential anti-HIV agent.
T2568L	Felypressin acetate 2-(L-Phenylalanine)-8-L-lysinevasopressin,醋酸苯赖加压素,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2	Vasopressin Receptor	GPCR/G Protein
	Felypressin acetate (PLV-2) 是加压素 1 的激动剂，作用于所有精氨酸加压素受体 1AS。 Felypressin acetate 可用于牙科手术。
T29704	AG-1812 free base UNII-6RI44GB0V9,HE078804,AC1MIZB6,Lansoprazole disulfide active metabolite
	ABT-1812 is a bio-active chemical.
T25821	ML359 ML-359,ML 359	Others	Others
	ML359 是选择性可逆的蛋白质二硫键异构酶有效抑制剂(IC50:250 nM)。它对体内血栓形成具有抑制作用。
T20470	Edetic acid Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA	Others	Others
	Edetic acid (Ethylenediaminetetraacetic acid) 是 Edetate 的酸形式，是一种具有抗高钙血症和抗凝血特性的螯合剂。它与钙和重金属离子结合后，会形成可溶的稳定复合体，使血清钙水平降低。它也可用作血液样本的抗凝剂，并用于治疗铅中毒。
T6800	CCF642 AC1LYELL	Others	Others
	CCF642 (AC1LYELL) 是蛋白质二硫键异构酶抑制剂(IC50:2.9 μM)。它在多发性骨髓瘤细胞中引起急性内质网应激，并伴随凋亡诱导的钙释放，表现出广泛的抗多发性骨髓瘤作用。
T76582	Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)
	Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)，为含环状RGD活性序列的十肽，作为整合素(Integrin)αIIbβ3的拮抗剂，能够抑制血小板与proMMP-13的粘附。
T126449	Hirudonucleodisulfide B
	Hirudonucleodisulfide B 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126449。
T19106	2-(Pyridyldithio)ethylamine hydrochloride 2-(2-吡啶基二硫基)乙胺盐酸盐,(S)-2-Pyridylthio Cysteamine Hydrochloride	Others	Others
	2-(Pyridyldithio)ethylamine hydrochloride ((S)-2-Pyridylthio Cysteamine Hydrochloride) 是新型的二硫化物插入交联剂。
T41277	PACMA 31	Others	Others
	PACMA 31 是一种不可逆的共价蛋白二硫键异构酶 (PDI) 抑制剂，IC50 为 10 μM。 PACMA 31 显着抑制卵巢肿瘤生长并表现出肿瘤靶向能力。
TP1474	LXW7	Integrin	Cytoskeletal Signaling
	LXW7 是一种整合素αvβ3抑制剂，是含 Arg-Gly-Asp (RGD) 的环状肽，对αvβ3整联蛋白具有很高的结合亲和力，IC50为 0.68 μM。它可增强 VEGFR-2 磷酸化和 ERK1/2 活化，具有抗炎活性。
T19925	EcDsbB-IN-9	Others	Others
	EcDsbB-IN-9 是一种特异性 EcDsbB 抑制剂，靶向革兰氏阴性菌的二硫键形成酶 DsbB。
T36511	WSP-1
	WSP-1 是一种具有选择性且用于硫化氢检测的2-吡啶基二硫醚荧光探针，可用于硫化氢检测和生物成像。
T18529	PDEC-NB 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate	Others	Others
	PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) 是用于抗体-药物偶联物的二硫键可切割接头。
T5453	3-Methyltoxoflavin 3-methyl toxoflavin	Others	Others
	3-Methyltoxoflavin (3-methyl toxoflavin) 是蛋白质二硫键异构酶抑制剂(IC50:170 nM)。
T8587	EcDsbB-IN-12 4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one	Others	Others
	EcDsbB-IN-12 (4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one) 靶向二硫键形成酶，是一种新型强效特异性EcDsbB 抑制剂。
T4552	Fursultiamine Diteftin,呋喃硫胺,Judolor,Alinamin F	Others	Others
	Fursultiamine (Alinamin F) 是维生素 B1衍生物，具有抗伤害和抗肿瘤作用。它可用于研究维生素 B1缺乏病、骨关节炎和癌症。
T11141	E64FC26	Others	Others
	E64FC26 是一种有效的蛋白质二硫键异构酶 (PDI) 家族泛抑制剂，具有抗肿瘤活性，抑制 PDIA1、PDIA3、PDIA4、TXNDC5 和 PDIA6，可用于研究多发性骨髓瘤和胰腺癌。
T4346	SPDB	Others	Others
	SPDB 是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。它是一个与 DM4 偶联物相连的小片段，利用二硫键与抗体偶联。
T15076	DBCO-S-S-PEG3-biotin 生物素-PEG3-二硫-DBCO	Others; PROTAC Linker	Others; PROTAC
	DBCO-S-S-PEG3-biotin 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
TP2325L	Endotoxin Inhibitor acetate(147396-10-9 free base)	Others	Others
	Endotoxin Inhibitor acetate(147396-10-9 free base) 对细菌生理活性有很强的阻断作用，从而产生具有二硫键和大量赖氨酸的抗菌毒素抑制剂序列。内毒素抑制剂醋酸盐在酸性条件下更可能发挥生理活性
T6741	SPDP SPDP Crosslinker	Others	Others
	SPDP 是一种短链交联剂，用于通过 NHS 酯和吡啶基二硫醇反应基团与半胱氨酸巯基形成可切割（可还原）的二硫键，实现胺与巯基的共轭。它是一种可降解的 ADC 连接剂，可用于合成抗体偶联药物。
T39704	KSC-34	Others	Others
	KSC-34 是蛋白二硫异构酶 A1（PDIA1）的共价修饰剂，是一种针对 PDIA1 的 a 位点的选择性抑制剂，以时间依赖的方式抑制PDIA1 还原酶活性，可用于研究淀粉样蛋白异常引起的疾病。
T60446	LCS3	Apoptosis; Glutathione reductase	Apoptosis; oxidation-reduction
	LCS3是一种可逆和非竞争性的谷胱甘肽二硫化物还原酶（GSR）和硫氧还蛋白还原酶1（TXNRD1）的协同抑制剂，IC50分别为3.3μM 和3.8μM。LCS3具有抗肿瘤活性，可诱导细胞凋亡，可用于研究肺腺癌（LUAD）。
T27417L	Glutathione arsenoxide hydrochloride GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)	Apoptosis; AChR	Apoptosis; Neuroscience
	Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) 是一种潜在的抗癌活性分子和肿瘤代谢抑制剂。Glutathione arsenoxide hydrochloride 靶向线粒体内膜腺嘌呤核苷酸转移酶 (ANT)，对细胞增殖有抑制作用，促进细胞凋亡。Glutathione arsenoxide hydrochloride 可用于识别如蛋白质二硫异构酶一样的细胞表面蛋白质。
T2283	PX-12 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12	Thioredoxin	Metabolism
	PX-12 (PX12) 是一种可逆的硫氧还蛋白-1(Trx-1)抑制剂，能够抑制 MCF-7 细胞(IC50:1.9 μM)和HT-29 细胞(IC50:2.9 μM)的生长。
TP1604L	Thioredoxin reductase peptide acetate Thioredoxin reductase peptide acetate(950890-23-0 free base)	Others	Others
	Thioredoxin reductase peptide acetate(950890-23-0 free base) 对应于硫氧还蛋白还原酶 (TrxR) 中的 53–67 位残基，用于硫氧还蛋白还原酶研究。哺乳动物硫氧还蛋白还原酶 (TR) 催化硫氧还蛋白 (Trx) 的氧化还原活性二硫键的还原，并且在结构和谷胱甘肽还原酶的作用机制，除了 C 末端的 16 个氨基酸延伸部分含有一个罕见的连位硒硫键。
T0983L	DL-Penicillamine 3-Sulfanylvaline,DL-青霉胺	Antibiotic	Microbiology/Virology
	DL-Penicillamine (3-Sulfanylvaline) 是一种螯合剂，推荐用于去除威尔逊病患者体内多余的铜。它仅存在于使用或服用该药物的个体中。它是青霉素类抗生素最具特征的降解产物。它被用作抗风湿药和威尔逊病的螯合剂。
T3161L	BACE-IN-1 acetate BACE-IN-1 acetate (350228-37-4，Free base)	BACE	Neuroscience
	BACE-IN-1 acetate (BACE-IN-1 acetate (350228-37-4，Free base)) 已被用作 BACE1 抑制剂测定中的 β 位淀粉样前体蛋白 (APP) 裂解酶-1 (BACE1) 抑制剂。 β-位点淀粉样前体蛋白 (APP) 切割酶-1 (BACE1)是一种天冬氨酸蛋白酶，属于蛋白酶家族，由六个腔内半胱氨酸残基组成。这些残基有助于形成三个分子间二硫键和 N-连接的糖基化位点。
T17731L	CL2A-SN-38 DCA 1279680-68-0(free base)	Others	Others
	CL2A-SN-38 DCA 1279680-68-0(free base) 是一种药物-接头偶联物，由有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成，用于制造抗体药物偶联物 (ADC)。CL2A-SN-38 由有效的 DNA 拓扑异构酶组成I 抑制剂 SN-38 和接头 CL2A 以制造抗体药物偶联物 (ADC)。 CL2A-SN-38 对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 CL2A 是一种不可切割的复杂 PEG8 和含有三唑的 PABC-肽-mc 接头。 CL2A 可通过 pH 敏感性裂解，产生旁观者效应，并通过二硫键在半胱氨酸残基处结合抗体。
T24608	PDI-IN-P1 PDI inhibitor P1,PDIINP1,PDI-inhibitor-P1
	PDI-IN-P1 is an inhibitor of protein disulfide isomerase.

化合物

Diphenyl disulfide

Cat.No: T37518

Synonym: Phenyl disulfide

Target: Apoptosis, BCL, Endogenous Metabolite

2,2′-Dipyridyl disulfide

Cat.No: T19780

Synonym: 2,2'-Dipyridyl disulfide,OPSS,2,2'-二硫二吡啶,Aldrithiol 2,Orthopyridyl disulfide

Target: Others

Diisopropyl xanthogen disulfide

Cat.No: T31479

Synonym: NSC1339,NSC 1339,Isopropylxanthic disulfide,二硫化二异丙基黄原酸酯,NSC-1339

Target: Others

Thiamine disulfide

Cat.No: T20062

Synonym: 二硫化硫胺,TDS,Daiomin,Algoneurina

Target: HIV Protease, Endogenous Metabolite

Transdermal Peptide Disulfide Acetate

Cat.No: TP1033L

Synonym: TD 1 (peptide) acetate,Transdermal Peptide Disulfide Acetate (888486-23-5 free base)

Target: ATPase

Thiola-cysteine disulfide

Cat.No: T34853

Synonym: Mercaptopropionylglycine-cysteine disulfide

Cat.No: T21089

Synonym: 3,3'-Dinitrodiphenyl disulfide,3,3'-二硝基二苯二硫醚

Target: Dehydrogenase

L-Cysteine-glutathione disulfide

Cat.No: T38312

Famotidine disulfide

Cat.No: T71049

Transdermal Peptide Disulfide TFA

Cat.No: T37767

Xylyl disulfide

Cat.No: T19968

1-N-Methyl-4-mercaptohistidine disulfide

Cat.No: T83633

Target: Others

Thiorphan disulfide

Cat.No: T71161

Cat.No: T0054

Synonym: 双硫伦,Tetraethylthiuram disulfide,双硫仑,NSC 190940,TETD

Target: Dehydrogenase, Interleukin, Pyroptosis

Captopril disulfide

Cat.No: T20512

Synonym: SQ14,551,SQ 14,551,SQ-14,551

Molybdenum disulfide

Cat.No: T19986

Synonym: Moly Powder B,Molykote Microsize Powder,T-Powder,Molysulfide,Natural molybdenite

Transdermal Peptide Disulfide

Cat.No: TP1033

Synonym: Transdermal Peptide,TD 1 (peptide)

2-Hydroxyethyl disulfide mono-tosylate

Cat.No: T14016

Target: Others

Bis-Tos-(2-hydroxyethyl disulfide)

Cat.No: T14663

Target: Others

Cat.No: T26823

Synonym: Bisbutitiamine,Bisbutiamine,o-Butyrylthiamine disulfide

Felypressin acetate

Cat.No: T2568L

Synonym: 2-(L-Phenylalanine)-8-L-lysinevasopressin,醋酸苯赖加压素,PLV2. H-Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond),PLV 2,PLV-2

Target: Vasopressin Receptor

AG-1812 free base

Cat.No: T29704

Synonym: UNII-6RI44GB0V9,HE078804,AC1MIZB6,Lansoprazole disulfide active metabolite

Cat.No: T25821

Synonym: ML-359,ML 359

Target: Others

Cat.No: T20470

Synonym: Ethylenediaminetetraacetic acid,乙二胺四乙酸,EDTA

Target: Others

Cat.No: T6800

Synonym: AC1LYELL

Target: Others

Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)

Cat.No: T76582

Hirudonucleodisulfide B

Cat.No: T126449

2-(Pyridyldithio)ethylamine hydrochloride

Cat.No: T19106

Synonym: 2-(2-吡啶基二硫基)乙胺盐酸盐,(S)-2-Pyridylthio Cysteamine Hydrochloride

Target: Others

Cat.No: T41277

Target: Others

Cat.No: TP1474

Target: Integrin

Cat.No: T19925

Target: Others

Cat.No: T36511

Cat.No: T18529

Synonym: 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate

Target: Others

3-Methyltoxoflavin

Cat.No: T5453

Synonym: 3-methyl toxoflavin

Target: Others

Cat.No: T8587

Synonym: 4,5-dichloro-2-[(2-chlorophenyl)methyl]pyridazin-3-one

Target: Others

Cat.No: T4552

Synonym: Diteftin,呋喃硫胺,Judolor,Alinamin F

Target: Others

Cat.No: T11141

Target: Others

Cat.No: T4346

Target: Others

DBCO-S-S-PEG3-biotin

Cat.No: T15076

Synonym: 生物素-PEG3-二硫-DBCO

Target: Others, PROTAC Linker

Endotoxin Inhibitor acetate(147396-10-9 free base)

Cat.No: TP2325L

Target: Others

Cat.No: T6741

Synonym: SPDP Crosslinker

Target: Others

Cat.No: T39704

Target: Others

Cat.No: T60446

Target: Apoptosis, Glutathione reductase

Glutathione arsenoxide hydrochloride

Cat.No: T27417L

Synonym: GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)

Target: Apoptosis, AChR

Cat.No: T2283

Synonym: 2-[(1-甲基丙基)二硫代]-1H-咪唑,IV-2,PX12

Target: Thioredoxin

Thioredoxin reductase peptide acetate

Cat.No: TP1604L

Synonym: Thioredoxin reductase peptide acetate(950890-23-0 free base)

Target: Others

DL-Penicillamine

Cat.No: T0983L

Synonym: 3-Sulfanylvaline,DL-青霉胺

Target: Antibiotic

BACE-IN-1 acetate

Cat.No: T3161L

Synonym: BACE-IN-1 acetate (350228-37-4，Free base)

Target: BACE

CL2A-SN-38 DCA 1279680-68-0(free base)

Cat.No: T17731L

Target: Others

Cat.No: T24608

Synonym: PDI inhibitor P1,PDIINP1,PDI-inhibitor-P1

Cat. No.	Product Name	Target	Signaling Pathways
TN1576	Diallyl disulfide	IL Receptor; NOS; NF-κB	Immunology/Inflammation; NF-κB
	Diallyl disulfide 能够抑制人角鲨烯单加氧酶，抑制角鲨烯环氧化的 IC50为 400 μM。它也具有抗肿瘤作用，同miR-200b 和miR-22联合使用可增强该作用。
TN6758	PROPYL DISULFIDE	Others	Others
	PROPYL DISULFIDE 是一种天然产物。
T39668	Methyl propyl disulfide	Others	Others
	Methyl propyl disulfide 是在大蒜和洋葱中产生的挥发性含硫化合物，具有抗癌活性。
T8051	Bis(2-methyl-3-furyl)disulfide 双(2-甲基-3-呋喃基)二硫,Bis(2-methyl-3-furyl)disulphide	Others	Others
	Bis(2-methyl-3-furyl)disulfide 是调味剂，能够增强与牛奶相关的产品的自然感，清新感。
T0905	Pyrithioxin 吡硫醇,Pyridoxine disulfide,Encefabol,Vitamin B6 disulfide,Pyritinol,Bonifen,吡硫醇(维生素B6衍生品)	Others; Endogenous Metabolite	Metabolism; Others
	Pyrithioxin (Encefabol) 是神经动力化合物，能够促进脑内葡萄糖及氨基酸的代谢，改善全身同化作用，增加颈动脉血流量，改善脑血流。
T0978	Pantethine LBF disulfide,Pantosin,Pantetina,Bis-pantethine,泛硫乙胺(维生素B5),泛硫乙胺,Pantomin,D-Pantethine	Endogenous Metabolite	Metabolism
	D-Pantethine (Pantomin) 是泛酸的二聚体形式, 是生产辅酶 A 的中间体。D-Pantethine 能够作为膳食补充剂，用于改善血液胆固醇和研究痤疮。
T1085L	Glutathione oxidized Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG	Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase	Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	Glutathione oxidized (L(-)-Glutathione) 是氧化型谷胱甘肽，谷胱甘肽是细胞内一种主要的抗氧化剂和解毒剂。
T82196	Hirudonucleodisulfide A
	Hirudonucledisulfide A为一杂环化合物，在Whitmania pigra中可被检出，展现出中等程度的抗缺氧活性。
T1085	L-Glutathione reduced 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion	Ferroptosis; Reactive Oxygen Species; Endogenous Metabolite; Glutathione reductase	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
	L-Glutathione reduced (Glutathione) 属于天然三肽，存在与细胞中，是一种内源性抗氧化剂，可以清除氧自由基。L-Glutathione reduced 是某些酶的辅助因子，参与蛋白质二硫键重排并减少过氧化物。
T82003	Juniferdin
	Juniferdin是一种抑制Protein disulfide isomerase (PDI)，IC50为3.5 μM，旨在阻断HIV传播的化合物。此外，Juniferdin展现出细胞毒性并能抑制血小板聚集。
T1080	2-Aminoethanethiol 2-Mercaptoethylamine,巯基乙胺,β-Mercaptoethylamine,β-MEA,Cysteamine	Apoptosis; Others; Reactive Oxygen Species; Cysteine Protease; Somatostatin; Endogenous Metabolite; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB; Others; Proteases/Proteasome
	2-Aminoethanethiol (Cysteamine) 是一种胱氨酸消耗剂。半胱胺的作用机制是胱氨酸二硫化物还原。
T73064	Rostratin C
	Rostratin C，一种具有细胞毒性的二硫化物，在体外对人结肠癌(HCT-116)展现出细胞毒性，IC50值为0.76 μg/mL。
T73063	Rostratin B
	Rostratin B为一种具体外细胞毒作用的二硫化物，针对人结肠癌HCT-116细胞线，展现了IC50值达1.9 μg/mL。
T73062	Rostratin A
	Rostratin A 是一种细胞毒性二硫化物，存在于海洋源性真菌Exserohilum rostratum 中。Rostratin A 对人结肠癌 (HCT-116) 具有体外细胞毒性，IC50值为 8.5μg/mL。
T5276	4,4'-Disulfanediylbis(2-aminobutanoic acid) DL-Homocystine,DL-高胱氨酸	Others; Endogenous Metabolite	Metabolism; Others
	4,4'-Disulfanediylbis(2-aminobutanoic acid) (DL-Homocystine) 是内源性代谢产物的一种。
T36448	(E)-Ajoene
	(E)-Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities.1,2,3,4It is active against Gram-positive and Gram-negative bacteria (MICs = 10-250 and 150->500 μg/ml, respectively) and fungi (MICs = 15-50 μg/ml).1(E)-Ajoene inhibits proliferation of a variety of cancer cells, including MDA-MB-231 breast, HeLa cervical, and WHCO1 esophageal cancer cells (IC50s = 18.6, 61, and 39.2 μM, respectively).2It also inhibits human glutathione reductase andT. cruzitrypanoth...
T35624	Ajoene
	Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 &#181g/ml) and Gram-negative bacteria (MICs = 136-200 &#181g/ml), as well as yeasts (MICs = 10-20 &#181g/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 &#181M), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 &#181M).2It reduces...

天然产物

Diallyl disulfide

Cat.No: TN1576

Target: IL Receptor, NOS, NF-κB

PROPYL DISULFIDE

Cat.No: TN6758

Target: Others

Methyl propyl disulfide

Cat.No: T39668

Target: Others

Bis(2-methyl-3-furyl)disulfide

Cat.No: T8051

Synonym: 双(2-甲基-3-呋喃基)二硫,Bis(2-methyl-3-furyl)disulphide

Target: Others

Cat.No: T0905

Synonym: 吡硫醇,Pyridoxine disulfide,Encefabol,Vitamin B6 disulfide,Pyritinol,Bonifen,吡硫醇(维生素B6衍生品)

Target: Others, Endogenous Metabolite

Cat.No: T0978

Synonym: LBF disulfide,Pantosin,Pantetina,Bis-pantethine,泛硫乙胺(维生素B5),泛硫乙胺,Pantomin,D-Pantethine

Target: Endogenous Metabolite

Glutathione oxidized

Cat.No: T1085L

Synonym: Bi(glutathion-S-yl),Oxidized glutathione,L-谷胱甘肽(氧化型),氧化型谷胱甘肽,L-Glutathione oxidized,Glutathione disulfide,L(-)-Glutathione,GSSG

Target: Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase

Hirudonucleodisulfide A

Cat.No: T82196

L-Glutathione reduced

Cat.No: T1085

Synonym: 谷胱甘肽,GSH,Isethion,Glutathione,γ-L-Glutamyl-L-cysteinyl-glycine,Glutathion,还原型谷胱甘肽,Tathion

Target: Ferroptosis, Reactive Oxygen Species, Endogenous Metabolite, Glutathione reductase

Cat.No: T82003

2-Aminoethanethiol

Cat.No: T1080

Synonym: 2-Mercaptoethylamine,巯基乙胺,β-Mercaptoethylamine,β-MEA,Cysteamine

Target: Apoptosis, Others, Reactive Oxygen Species, Cysteine Protease, Somatostatin, Endogenous Metabolite, Autophagy

Cat.No: T73064

Cat.No: T73063

Cat.No: T73062

4,4'-Disulfanediylbis(2-aminobutanoic acid)

Cat.No: T5276

Synonym: DL-Homocystine,DL-高胱氨酸

Target: Others, Endogenous Metabolite

Cat.No: T36448

Cat.No: T35624

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