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Search Results for " adrenergic blocking "

21

抑制剂 & 化合物

4

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19654	Guanoclor 胍氯酚,VATENSOL	Others	Others
	Guanoclor (VATENSOL) 也称为guanochlor，是一种交感神经药物。已知它与猪肾膜中的非肾上腺素能位点结合。
T0154	Nebivolol hydrochloride R 065824 hydrochloride,盐酸奈必洛尔,Nebivolol HCl,R-65824	Apoptosis; Adrenergic Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	Nebivolol hydrochloride (R 065824 hydrochloride) 是一种β1-肾上腺素受体选择性抑制剂，IC50为0.8 nM。
T25828	Monatepil maleate AJ2615,AJ 2615,AJ-2615
	Monatepil maleate is an Antihypertensive agent. It is a calcium antagonist with alpha(1)-adrenergic receptor blocking activity
T3996	Dapiprazole Hydrochloride 盐酸达哌唑,Glamidolo Hydrochloride,Reversil Hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dapiprazole Hydrochloride (Glamidolo Hydrochloride) 是 α-adrenergic 阻断剂的药物。
T24588	Palatrigine BW-A 256C,BW A256C	Adrenergic Receptor; Angiotensin-converting Enzyme (ACE)	GPCR/G Protein; Metabolism; Neuroscience
	Palatrigine (BW-A 256C) 是一种具有血管紧张素转换酶抑制和β肾上腺素受体阻断特性的化合物。
T0074L	Chlorprothixene hydrochloride NSC 78193,Minithixen,泰尔登盐酸盐,Truxal hydrochloride,盐酸氯普噻吨,NSC 56379,NSC 169899,Minithixen hydrochloride	Dopamine Receptor; 5-HT Receptor; Antibacterial; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Chlorprothixene hydrochloride (Truxal hydrochloride) 是一种多巴胺和组胺受体拮抗剂，具有抗精神病作用，高亲和力地结合人 D1，D2，D3，D5，H1 受体，Ki 分别为 18 nM，2.96 nM，4.56 nM，9 nM 和 3.75 nM。
T0394	Moxisylyte hydrochloride 莫西赛利盐酸盐,Thymoxamine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Moxisylyte hydrochloride (Thymoxamine hydrochloride) 是一种 alpha 1-blocker 的拮抗剂，能在不减少血管压力的情况下，扩张大脑血管。
T37906	Dibenamine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dibenamine hydrochloride 是竞争性的、不可逆的肾上腺素能阻断剂，可以修饰肾上腺素的药理作用。它对小鼠体内肾上腺素的破坏率显著增加。
T0342	Carvedilol phosphate hemihydrate Carvedilol phosphate,BM 14190 (phosphate hemihydrate),卡维地洛磷酸盐	VEGFR; Others; Potassium Channel; LDL; Integrin; Gap Junction Protein; NADPH; Adrenergic Receptor; Autophagy	Angiogenesis; Autophagy; Cytoskeletal Signaling; GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience; Others; Tyrosine Kinase/Adaptors
	Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) 是一种外消旋混合物，是一种非选择性β/α-1受体阻断剂，具有抗高血压活性且缺乏内在拟交感神经活性。
T3979	Emedastine LY188695,依美斯汀,Emadine	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Emedastine (LY188695) 是一种可口服的，选择性和高亲和力的组胺 H1受体拮抗剂，Ki 值为 1.3 nM。它是苯并咪唑衍生物，可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T30606	Bucumarol (HCl) Bucumarol,CS 359
	Bucumarol is a beta-adrenergic blocking agent.
T24892	Tolboxane JS 813,IS 813,NSC-169422,NSC169422,NSC 169422
	Tolboxane is an alpha-adrenergic blocking drug.
T33437	MK761 MK 761,MK-761
	MK761 has β-adrenergic receptor antagonist and vasodilator properties in a single molecule and is as effective at blocking cardiac and vascular β-adrenergic receptors as timolol and indololol. The compound exhibited β-adrenergic receptor blocking activity
T14287	Ancarolol	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Ancarolol is a blocking agent of beta-adrenergic.
T13585	Bometolol Hydrochloride	Others	Others
	Bometolol Hydrochloride is a beta-adrenergic blocking compound used for the treatment of cardiovascular disease.
T16066	Metipranolol hydrochloride	Others	Others
	Metipranolol hydrochloride is a non-selective blocking agent of the β adrenergic receptor.
T25661	Lenperone Lenperonum,AHR-2277 [as hydrochloride]
	Lenperone is a butyrophenone antipsychotic. Like other major tranquilizers, It has some alpha-adrenergic blocking action and is antiemetic.
T71377	Oberadilol
	Oberadilol is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory action
T9097L	Guanadrel Sulfate CL 1388R,U 28288D,CHEBI:5556,Hylorel,Hyloride
	Guanadrel Sulfate is a postganglionic adrenergic blocking agent. The uptake of guanadrel and storage in sympathetic neurons occurs via the norepinephrine pump or transporter.
T71376	Tzc 5665
	Tzc 5665 is a pyridazinone derivative with vasodilatory and beta-adrenergic blocking activities and type III phosphodiesterase inhibitory action.
T60834	Phentolamine hydrochloride
	Phentolamine hydrochloride

化合物

Cat.No: T19654

Synonym: 胍氯酚,VATENSOL

Target: Others

Nebivolol hydrochloride

Cat.No: T0154

Synonym: R 065824 hydrochloride,盐酸奈必洛尔,Nebivolol HCl,R-65824

Target: Apoptosis, Adrenergic Receptor

Monatepil maleate

Cat.No: T25828

Synonym: AJ2615,AJ 2615,AJ-2615

Dapiprazole Hydrochloride

Cat.No: T3996

Synonym: 盐酸达哌唑,Glamidolo Hydrochloride,Reversil Hydrochloride

Target: Adrenergic Receptor

Cat.No: T24588

Synonym: BW-A 256C,BW A256C

Target: Adrenergic Receptor, Angiotensin-converting Enzyme (ACE)

Chlorprothixene hydrochloride

Cat.No: T0074L

Synonym: NSC 78193,Minithixen,泰尔登盐酸盐,Truxal hydrochloride,盐酸氯普噻吨,NSC 56379,NSC 169899,Minithixen hydrochloride

Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, AChR, Histamine Receptor

Moxisylyte hydrochloride

Cat.No: T0394

Synonym: 莫西赛利盐酸盐,Thymoxamine hydrochloride

Target: Adrenergic Receptor

Dibenamine hydrochloride

Cat.No: T37906

Target: Adrenergic Receptor

Carvedilol phosphate hemihydrate

Cat.No: T0342

Synonym: Carvedilol phosphate,BM 14190 (phosphate hemihydrate),卡维地洛磷酸盐

Target: VEGFR, Others, Potassium Channel, LDL, Integrin, Gap Junction Protein, NADPH, Adrenergic Receptor, Autophagy

Cat.No: T3979

Synonym: LY188695,依美斯汀,Emadine

Target: Histamine Receptor

Bucumarol (HCl)

Cat.No: T30606

Synonym: Bucumarol,CS 359

Cat.No: T24892

Synonym: JS 813,IS 813,NSC-169422,NSC169422,NSC 169422

Cat.No: T33437

Synonym: MK 761,MK-761

Cat.No: T14287

Target: Adrenergic Receptor

Bometolol Hydrochloride

Cat.No: T13585

Target: Others

Metipranolol hydrochloride

Cat.No: T16066

Target: Others

Cat.No: T25661

Synonym: Lenperonum,AHR-2277 [as hydrochloride]

Cat.No: T71377

Guanadrel Sulfate

Cat.No: T9097L

Synonym: CL 1388R,U 28288D,CHEBI:5556,Hylorel,Hyloride

Cat.No: T71376

Phentolamine hydrochloride

Cat.No: T60834

Cat. No.	Product Name	Target	Signaling Pathways
T2142	Yohimbine hydrochloride 盐酸育亨宾,Antagonil,Yohimbine HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Yohimbine hydrochloride (Antagonil) 是一种植物生物碱，具有 α-2-肾上腺素能阻断活性。它被用作散瞳药和治疗勃起功能障碍。
T0266	Quinidine hydrochloride monohydrate 奎宁树,奎尼丁盐酸盐一水合物,奎尼丁盐酸盐,Quinidine hydrochloride	Potassium Channel; Sodium Channel; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	Quinidine hydrochloride monohydrate 是一种抗心律失常剂，也是 K+通道 (K+channel) 的有效阻断剂，其IC50值为 19.9 μM。它是一种有效且选择性的细胞色素 P450db (cytochrome P450db) 抑制剂，也可用作疟疾的研究。
T19910	Corynanthine NSC-407306,NSC407306,NSC 407306
	Corynanthe is a plant alkaloid. Corynanthe also has an alpha-2-adrenergic blocking activity.
T2S1727	Lycorenine	Antifection	Microbiology/Virology
	Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and produce bradycardia by modifying vagal activity. The development of tachyph

天然产物

Yohimbine hydrochloride

Cat.No: T2142

Synonym: 盐酸育亨宾,Antagonil,Yohimbine HCl

Target: Adrenergic Receptor

Quinidine hydrochloride monohydrate

Cat.No: T0266

Synonym: 奎宁树,奎尼丁盐酸盐一水合物,奎尼丁盐酸盐,Quinidine hydrochloride

Target: Potassium Channel, Sodium Channel, Parasite

Cat.No: T19910

Synonym: NSC-407306,NSC407306,NSC 407306

Cat.No: T2S1727

Target: Antifection

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