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Search Results for " tnf-r "
Targets Recommended: TNF

10

抑制剂 & 化合物

3

天然产物

29

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T4637 R-7050

TNF-α Antagonist III

TNF Apoptosis
R-7050 (TNF-α Antagonist III) 是一种肿瘤坏死因子受体拮抗剂,对 TNFα具有更高选择性。
T3185 R112

(E)-Elafibranor

Syk Angiogenesis; Tyrosine Kinase/Adaptors
R112 ((E)-Elafibranor) 是ATP 竞争性的 Syk 激酶抑制剂,它能够抑制Syk 激酶活性,Ki=6 nM,IC50=226 nM。
T6927 Pamapimod

R1503,帕吡莫德,Ro4402257

p38 MAPK; Autophagy Autophagy; MAPK
Pamapimod (R1503) 是一种新型的选择性 p38 丝裂原活化蛋白激酶抑制剂,对于p38α和p38β的IC50分别为 14 nM 和 480 nM,Ki 分别为 1.3 nM 和 120 nM,对 p38δ 或 p38γ 亚型没有活性,可研究类风湿关节炎和其他自身免疫性疾病。
TQ0181 Resatorvid

CLI-095,TAK-242,瑞沙托维

TNF; TLR; Autophagy; Interleukin Apoptosis; Autophagy; Immunology/Inflammation
Resatorvid (TAK-242) 是一种 Toll 样受体 4 (TLR4) 的抑制剂,具有选择性。Resatorvid 直接与 Cys747 结合,阻止 TLR4 与 TIRAP 结合,从而阻止下游信号转导。Resatorvid 具有抗肿瘤活性、抗炎活性和神经保护作用。
T60657 (R)-STU104

TNF; MAPK Apoptosis; MAPK
(R)-STU104 是一种新型 TAK1-MKK3 蛋白-蛋白相互作用 (PPI)抑制剂,抑制 TNF-α,通过与 MKK3 结合并破坏TAK1磷酸化MKK3来抑制TAK1/MKK3/p38/MnK1/MK2/elF4E信号通路。(R)-STU104 是治疗溃疡性结肠炎的候选化合物。
T9645 CU-115

N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide

TLR Immunology/Inflammation
CU-115 是一种有效的,选择性的 TLR8 拮抗剂。CU-115对 TLR8 和 TLR7的 IC50分别为1.04 µM 和=>50 µM。THP-1 细胞中,CU-115 减少了 R-848 激活的 TNF-α 和 IL-1β 的产生。
T68620 (R)-DOI hydrochloride

(R)-DOI hydrochloride is a 5-HT2 receptor agonist, inhibiting TNF-α-mediated proinflammatory signaling cascades and inflammation via 5-HT2A receptor activation and preventing the development of, and inflammation associated with, acute allergic asthma.
T38339 R-8507

R-8507 is a small molecule antagonist of the TNF-α type 1 receptor (TNFRI). It inhibits the expression of intercellular adhesion molecule-1 (ICAM-1) induced by TNF-α and IL-1β with EC50 values of 2.45 and 3.79 μM, respectively, in an ELISA using A549 lung epithelial cells.{|Gururaja2007|} It also disrupts the interaction of the TNFRI with receptor interacting protein 1 (RIP1) and TNFR-associated death domain protein (TRADD), preventing internalization of the receptor complex.
T36043 17(R)-Protectin D1

17(R)-Protectin D1

17(R)-Protectin D1 is an aspirin-triggered epimer of the specialized pro-resolving mediator protectin D1 .1It decreases leukotriene B4-induced transendothelial migration of human polymorphonuclear (PMN) neutrophils when used at concentrations ranging from 0.1 to 10 nM. 17(R)-Protectin D1 (0.01-10 ng) reduces the recruitment of neutrophils in a mouse model of TNF-α-induced peritonitis. 1.Serhan, C.N., Fredman, G., Yang, R., et al.Novel proresolving aspirin-triggered DHA pathwayChem. Biol.18(18)97...
T83895 NCI 126224

NSC 126224

NCI 126224 是一种 toll-like receptor 4 (TLR4) 的拮抗剂。它在 RAW 264.7 巨噬细胞中,选择性抑制由 TLR4 激动剂 LPS 引起的一氧化氮 (NO) 产生(IC50 = 0.31 µM),而对 TLR7/8 激动剂 R-848、TLR1/2 激动剂 Pam3CSK4 以及 TLR3 激动剂 poly(I:C) 的影响较小;但对于相同细胞中由 TLR2/6 激动剂 FSL-1 引起的 NO 产生,其抑制作用在 0.6 µM 时亦显现。此外,NCI 126224 在 BV-2 微胶质细胞的报告实验中抑制了 LPS 引起的 NF-κB 活性,并在 RAW 264.7 巨噬细胞中降低了 LPS 引起的 IL-1β 和 TNF-α 水平(IC50s = 5.92, 0.42, 和 1.54 µM,分别)。

化合物

R-7050
Cat.No: T4637
Synonym: TNF-α Antagonist III
Target: TNF
R112
Cat.No: T3185
Synonym: (E)-Elafibranor
Target: Syk
Pamapimod
Cat.No: T6927
Synonym: R1503,帕吡莫德,Ro4402257
Target: p38 MAPK, Autophagy
Resatorvid
Cat.No: TQ0181
Synonym: CLI-095,TAK-242,瑞沙托维
Target: TNF, TLR, Autophagy, Interleukin
(R)-STU104
Cat.No: T60657
Synonym:
Target: TNF, MAPK
CU-115
Cat.No: T9645
Synonym: N-(4-(3,5-bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide
Target: TLR
(R)-DOI hydrochloride
Cat.No: T68620
Synonym:
Target:
R-8507
Cat.No: T38339
Synonym:
Target:
17(R)-Protectin D1
Cat.No: T36043
Synonym: 17(R)-Protectin D1
Target:
NCI 126224
Cat.No: T83895
Synonym: NSC 126224
Target:
Cat. No. Product Name Target Signaling Pathways
TN6967 (R)-Isomucronulatol

(-)-Isomucronulatol,2H-1-Benzopyran-7-ol

Apoptosis Apoptosis
(R)-Isomucronulatol (2H-1-Benzopyran-7-ol) 是一种可从黄芪、刺槐、虎杖和甘草叶片中提取得到的类黄酮,抑制BMSCs 在TNF-α微环境中的增殖和凋亡。(R)-Isomucronulatol 具有潜在的抗炎活性。
T3893 Forsythoside B

连翘酯苷 B,连翘脂苷B

TNF; NF-κB Apoptosis; NF-κB
Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha,IL-6,IκB, 调节 NF-κB。它抑制炎症反应,具有抗氧化和神经保护作用。
T3775 Armepavine

亚美罂粟碱,R-Armepavine,(-)-Armepavine

IκB/IKK; NF-κB NF-κB
Armepavine (R-Armepavine) 是来自Nelumbo nucifera 的活性化合物,能够抑制 TNF-α 诱导的MAPK 和NF-κB 信号级联反应。它不仅对人外周血单核细胞具有抗炎作用,且对 T 淋巴细胞和狼疮肾炎小鼠也具有免疫抑制作用。

天然产物

(R)-Isomucronulatol
Cat.No: TN6967
Synonym: (-)-Isomucronulatol,2H-1-Benzopyran-7-ol
Target: Apoptosis
Forsythoside B
Cat.No: T3893
Synonym: 连翘酯苷 B,连翘脂苷B
Target: TNF, NF-κB
Armepavine
Cat.No: T3775
Synonym: 亚美罂粟碱,R-Armepavine,(-)-Armepavine
Target: IκB/IKK, NF-κB
Cat. No. Product Name Species Expression System
TMPY-02535 TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)

TNFalpha-R1,TNFAR,TN...

Mouse HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118.
TMPY-01459 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)

p60,TNFR60,TNFAR,TBP1,CD...

Human HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1.
TMPY-01697 TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)

Tnfr-1,TNFR80,TNF

Mouse HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P25119.
TMPY-01166 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)

TNFR80,p75,TNF-R75,T...

Human HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P20333-1.
TMPY-05039 LTBR Protein, Human, Recombinant (hFc)

TNFR-RP,lymphotoxin β re...

Human HEK293 Cells
LTBR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P36941-1.
TMPY-01639 TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)

TNFalpha-R1,TNFRp55,CD12...

Mouse HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is P25118.
TMPY-05475 TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc)

MS5,p55-R,p60,TNFR1-d2,TNF

Human HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P19438-1.
TMPK-00564 TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)

TBP1,TNF-RI,TNFAR,p55,p6...

Cynomolgus HEK293 Cells
Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling.
TMPY-01696 TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)

TNFR2,TNF-R-II,Tnf...

Mouse HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.3 kDa and the accession number is P25119.
TMPY-06600 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated

TNFR1B,TNF-R75,TBPII,p75...

Human HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.39 kDa and the accession number is NP_001057.1.
TMPY-05814 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His), Biotinylated

p75,TBPII,TNF-R-II,CD120b,p75TNF<...

Human HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P20333-1.
TMPY-00934 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & hFc)

TNF-R75,TBPII,TNF-R-II,<...

Human HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 53 kDa and the accession number is P20333-1.
TMPY-03881 TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (aa 1-268, M196A, His)

TNFR80,p75TNFR,TNF

Human HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (aa 1-268, M196A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is P20333-2.
TMPK-00176 BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)

BLyS,TALL-1,TNFSF13B,DTL,TNFSF20,TALL-1δ B...

Human HEK293 Cells
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 52.4 kDa an...
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TRDL-1,TNF- and APOL-related leuk...

Human HEK293 Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept...
TMPK-00070 BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated

CD268,TNFRSF13C,BAFFR,BR...

Human HEK293 Cells
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
TMPK-01254 BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)

CVID4,prolixin,TNFRSF13C,CD268,B<...

Cynomolgus HEK293 Cells
BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
TMPK-01163 APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)

TRDL1,TALL2,TALL-2,APRILFLJ57090,APR

Mouse HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 18.53 kDa and the accession number is Q9D777.
TMPK-00141 APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)

2310026N09Rik,TALL-2,TNFSF13,APRI...

Human HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 49.9 kDa and the accession number is O75888-1.
TMPK-00140 APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated

APRIL,TRDL1,TALL2,TALL-2,CD256,TNF

Human HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi and N-Flag tag. The predicted molecular weight is 52.1 kDa and the acce...
TMPK-00142 APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

TALL-2,CD256,TRDL1,APRILFLJ57090,APR

Human HEK293 Cells
The APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily.Both APRIL and its close relative BAFF bind and signal through the TNF superfamily receptors TACI and BCMA, while BAFF additionally functions through BAFF R. APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 49.9 kDa and...
TMPK-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)

ZTNFR9,DR5TRICK2B,DR...

Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
TMPK-00511 BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)

TALL1δ4 BAFF,BLyS,BAFF,TALL-1,TALL-1δ BAFF,TALL1Delta4 BAFF,...

Cynomolgus HEK293 Cells
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 54.2 kDa...
TMPK-00277 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)

TRAIL R2,TNFRSF10B,T...

Human HEK293 Cells
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
TMPK-00174 BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated

TALL1,TALL-1delta BAFF,TNFSF20,ZTNF4,THANK...

Human HEK293 Cells
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is...
TMPK-00510 BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated

THANK,TALL1Delta4 BAFF,TALL1δ4 BAFF,ZTNF4,TALL-1del...

Cynomolgus HEK293 Cells
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi and N-Flag tag. The predict...
TMPK-00175 BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag)

THANK,TALL1δ4 BAFF,TALL1Delta4 BAFF,TALL1,TNFSF20,T...

Human HEK293 Cells
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag) is expressed in HEK293 mammalian cells with N-monomeric hFc and N-Flag tag. The predicted molecular wei...
TMPJ-00067 BAFFR/TNFRSF13C Protein, Human, Recombinant (His)

BR3,BAFFR,CD268,TNFRSF13...

Human HEK293 Cells
Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. BAFF promotes the survival of B cells and is essential for B cell maturation. BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA/TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF...
TMPJ-00129 BTLA Protein, Human, Recombinant (His)

B- and T-Lymphocyte-Associated Protein,CD272,BTLA,B...

Human HEK293 Cells
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a ...

重组蛋白

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02535
Species: Mouse
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
Cat.No: TMPY-01459
Species: Human
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01697
Species: Mouse
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)
Cat.No: TMPY-01166
Species: Human
Expression System: HEK293 Cells
LTBR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05039
Species: Human
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01639
Species: Mouse
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05475
Species: Human
Expression System: HEK293 Cells
TNFR1/CD120a/TNFRSF1A Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00564
Species: Cynomolgus
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01696
Species: Mouse
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06600
Species: Human
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05814
Species: Human
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00934
Species: Human
Expression System: HEK293 Cells
TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (aa 1-268, M196A, His)
Cat.No: TMPY-03881
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00176
Species: Human
Expression System: HEK293 Cells
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPJ-00137
Species: Human
Expression System: HEK293 Cells
BAFFR/TNFRSF13C Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00070
Species: Human
Expression System: HEK293 Cells
BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01254
Species: Cynomolgus
Expression System: HEK293 Cells
APRIL/TNFSF13 Protein, Mouse, Recombinant (His & Flag)
Cat.No: TMPK-01163
Species: Mouse
Expression System: HEK293 Cells
APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00141
Species: Human
Expression System: HEK293 Cells
APRIL/TNFSF13 Trimer Protein, Human, Recombinant (His & Avi & Flag), Biotinylated
Cat.No: TMPK-00140
Species: Human
Expression System: HEK293 Cells
APRIL/TNFSF13 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Cat.No: TMPK-00142
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00276
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi)
Cat.No: TMPK-00511
Species: Cynomolgus
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00277
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00174
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Trimer Protein, Cynomolgus, Recombinant (His & Avi, Flag), Biotinylated
Cat.No: TMPK-00510
Species: Cynomolgus
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (monomeric hFc, Flag)
Cat.No: TMPK-00175
Species: Human
Expression System: HEK293 Cells
BAFFR/TNFRSF13C Protein, Human, Recombinant (His)
Cat.No: TMPJ-00067
Species: Human
Expression System: HEK293 Cells
BTLA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00129
Species: Human
Expression System: HEK293 Cells
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