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51

抑制剂 & 化合物

19

天然产物

18

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T30344	Benzamide, N-(8-(p-aminophenoxy)octyl)-
	Benzamide, N-(8-(p-aminophenoxy)octyl)- is a bioactive chemical.
T30068	Aniline, N-methyl-p-(8-phenoxyoctyloxy)-
	Aniline, N-methyl-p-(8-phenoxyoctyloxy)- is a Drug / Therapeutic Agent.
TP1931L1	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)	cholecystokinin	GPCR/G Protein
	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) 是广谱神经肽反向激动剂和拮抗剂。 ghrelin 受体的强效完全反向激动剂(EC50 = 5.2 nM)；减少组成型生长素释放肽受体信号传导。它也是速激肽、缓激肽、CCK 和铃蟾肽受体的拮抗剂。在体外诱导细胞凋亡并抑制癌细胞生长。
TP2103L	[D-p-Cl-Phe6,Leu17]-VIP acetate	Others	Others
	[D-p-Cl-Phe6,Leu17]-VIP acetate 是一种竞争性和选择性的血管活性肠肽 (VIP) 受体拮抗剂 (IC50 = 125.8 nM)。
TP2389	Laminin B1 octapeptide P-8 Asp-pro-gln-tyr-ile-gln-ser-arg,Dpgyigsr
	Laminin B1 octapeptide P-8 is a synthetic laminin B1 chain octapeptide with laminin receptor binding ability.
T40685L	Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base)	Others	Others
	Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (Orphan GPCR SP9155 agonist P550 ) 是具有促食欲作用的 RFamide 肽家族的成员。
T0089	Cetirizine dihydrochloride 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Cetirizine dihydrochloride (UCB P071) 是羟嗪的羧化代谢物，是特异性口服有效的 H1 受体长效拮抗剂。它标记抗过敏特性，抑制过敏反应期间嗜酸性粒细胞趋化，可有效治疗过敏性鼻炎、确诊荨麻疹和花粉诱发的哮喘。
TP1549L	NY-BR-1 p904 A2 acetate(347142-73-8 free base)	Others	Others
	NY-BR-1 p904 A2 acetate(347142-73-8 free base) 对这种 NY-BR-1 表位 (p904) 特异的 T 细胞克隆可以识别表达 NY-BR-1 的乳腺肿瘤细胞。
T9150	SCR130 1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-	Apoptosis; Others; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Others
	SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。它特异性依赖连接酶 IV，抑制 DNA 的末端连接。
T5962	TRPM8 antagonist WS-3 Cyclohexanecarboxamide,N-乙基-5-甲基-2-(1-甲基乙基)环己甲酰胺,N-Ethyl-p-menthane-3-carboxamide,N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM8 antagonist WS-3 (Cyclohexanecarboxamide) 是TRPM8的有效激动剂，其EC50值为 3.7 μM。
T39826	CBP/p300-IN-8 CBP/p300-IN-8
	CBP/p300-IN-8 is a potent inhibitor of the CBP/P300 family of bromodomains . CBP/p300-IN-8 inhibits CBP ( IC 50 =0.01-0.1 μΜ) and BRD4 ( IC 50 =1-1000 μΜ) activity.
T124022	8-p-Coumaroylharpagide

T11597L	IACS-9571 Hydrochloride (1800477-30-8 free base) IACS-9571 Hydrochloride,ASIS-P040 Hydrochloride	Epigenetic Reader Domain	Chromatin/Epigenetic
	IACS-9571 Hydrochloride is a selective and potent inhibitor of TRIM24 and BRPF1, (IC50: 8 nM for TRIM24; Kds: 31 nM and 14 nM for TRIM24 and BRPF1).
T5952	Diniconazole 烯唑醇,Rac-diniconazole	Antibacterial	Microbiology/Virology
	Diniconazole (Rac-diniconazole) 是新型杀菌剂, 抑制由酵母细胞色素P-450催化的羊毛甾醇14α-脱甲基化。
T36949	Niaprazine	5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Niaprazine 是有效的组胺 H1 受体拮抗剂，具有抗组胺和抗血清素活性。Niaprazine 在睡眠障碍方面有研究的价值。
T14492	BAL-30072	Others	Others
	BAL30072 shows MIC90 values of 4 μg/mL for MDR Acinetobacter spp. and 8 μg/mL for MDR P. aeruginosa, respectively[1][2]. BAL-30072, a siderophore sulfactam, is a monocyclic beta-lactam antibiotic, with activity against multiresistant gram-negative bacilli
T39958	(32-Carbonyl)-RMC-5552
	(32-Carbonyl)-RMC-5552 is a highly effective mTOR inhibitor, exhibiting inhibitory effects on both mTORC1 and mTORC2 substrate phosphorylation. Specifically, it significantly suppresses the phosphorylation of p-P70S6K-(T389), p-4E-BP1-(T37/36), and p-AKT1/2/3-(S473) with pIC50 values > 9, >9 and 8~9, respectively.
TNU0199	8-Hydroxyadenosine
	Nucleoside Derivatives - 8-Modified purine nucleosides; Drugs and Inhibitors; Anticancer antibiotics; oxidized nucleic acid adduct; precursor of phosmidosine (P-prodrug)
T28348	PD 404182 PD404182,PD-404182
	PD-404182, an inhibitor of KDO 8-P synthase (Ki = 26 nM), is a otential antibiotic of gram negative bacteria. PD-404182 also exhibits antiviral and antiangiogenic activity in vitro.
T67054	1-(P-Toluenesulfonyl)imidazole
	1-(P-Toluenesulfonyl)imidazole 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67054，CAS号为 2232-08-8。
T64762	P(t-Bu)3 Pd G3
	P(t-Bu)3 Pd G3 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64762，CAS号为 1445086-17-8。
T62936	Antimalarial agent 8
	Antimalarial agent 8 (Compound 7e) 是一种新型的、口服具有活力的抗疟药。Antimalarial agent 8 在体外能够有效作用于 P. falciparum，且在体内疟疾小鼠模型中口服有效 (40 mg/kg)。
T65805	L-Leucine benzyl ester p-toluenesulfonate salt
	L-Leucine benzyl ester p-toluenesulfonate salt 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65805，CAS号为 1738-77-8。
TMIH-0297	Ledipasvir-d6
	Ledipasvir-d6 是 Ledipasvir 的氘代化合物。Ledipasvir 的 CAS 号为 1256388-51-8。Ledipasvir 是一种丙型肝炎病毒 NS5A 抑制剂。它也是 P-糖蛋白抑制剂和乳腺癌抗性蛋白抑制剂。
T39672	Ac-Ile-Glu-Thr-Asp-pNA
	Ac-Ile-Glu-Thr-Asp-pNA is a caspase-8 substrate that undergoes enzymatic binding and cleavage specifically at the Ile-Glu-Thr-Asp (IETD) peptide sequence. This cleavage results in the release of p-nitroalinide, which can be quantitatively measured using colorimetric detection at 405 nm. This measure serves as an indicator of caspase-8 enzyme activity.
TNU1040	3-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)- α-D-glycero-pent-3-enofuranose
	3-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)- α-D-glycero-pent-3-enofuranose 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1040，CAS号为 75096-63-8。
T74496	LA-Bac8c
	LA-Bac8c为经硫辛酸修饰的抗菌肽，展现出增强的抗菌效能。针对金黄色葡萄球菌、MRSA、表皮葡萄球菌、大肠杆菌及铜绿假单胞菌的MIC值分别为1、4、8、8和8μg/mL，显示其对上述菌株具有强效的抑制作用。
T60315	Anti-infective agent 1
	Anti-infective agent 1 (化合物 3a) 是一种有效的、选择性的抗原生动物和抗结核分枝杆菌剂。Anti-infective agent 1 对P. falciparum 和T. brucei rhodesiense 具有抗寄生虫活性，IC50分别为 10.95 和 0.06 μM。Anti-infective agent 1 显示出对耻垢分枝杆菌的抗分支杆菌活性，MIC 为 8 μg/mL。
T83826	1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin 1,2,3,6,7,8-HxCDD,PCDD 67
	1,2,3,6,7,8-六氯二苯并-p-二噁英是一种多氯代二苯并二噁英（PCDD）。它是芳香烃受体（AhR; EC50s分别为5.4和9.3 nM，在4和8小时的报告检测中）的激动剂。1,2,3,6,7,8-六氯二苯并-p-二噁英（0.5和2 µg/kg）降低了小鼠对羊红血球的抗体产生。在动物饲料和靠近市政废物焚烧炉的空气中均有发现。
T36076	Ciprofibrate impurity A
	Ciprofibrate impurity A is an impurity of Ciprofibrate. Ciprofibrate is a PPARα agonist[1]. [1]. Passilly, P., et al., Phosphorylation of peroxisome proliferator-activated receptor alpha in rat Fao cells and stimulation by ciprofibrate. Biochem Pharmacol, 1999. 58(6): p. 1001-8.
T80274	Lynronne-1
	Lynronne-1 是一种具备抗革兰氏阳性细菌能力的抗菌肽，尤其对包括多重耐药(MDR)菌株有效（MRSA菌株的MIC为8-32 μg/mL）。在MRSA感染的伤口小鼠模型中，Lynronne-1能显著降低细菌负荷。此外，Lynronne-1对P. aeruginosa感染也显示出活性。
TP1054	PACAP (1-38), human, ovine, rat TFA Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)
	PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP),
T70507	KAI-407
	KAI407 is a potent non-8-aminoquinoline compound that kills Plasmodium cynomolgi early dormant liver stage parasites in vitro. KAI407 showed an activity profile similar to that of primaquine (PQ), efficiently killing the earliest stages of the parasites that become either primary hepatic schizonts or hypnozoites (50% inhibitory concentration [IC50] for hypnozoites, KAI407, 0.69 μM, and PQ, 0.84 μM; for developing liver stages, KAI407, 0.64 μM, and PQ, 0.37 μM). KAI407 may represent a new compou...
T36746	Leoidin
	Leoidin is a depsidone originally isolated from L. gangaleoides that has antibacterial and enzyme inhibitory activities.1,2,3 It is active against the bacteria E. faecalis, H. influenzae, M. catarrhalis, S. aureus, and S. pneumoniae (MICs = 8, 32, 1, 128, and 64 μg/ml, respectively).2 Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) isolated from P. aeruginosa (IC50 = 42 μM). It also inhibits organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 with Ki values of 0.08 and 1.84 μM...
T21633	N-3-oxo-dodecanoyl-L-Homoserine lactone
	N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL) 是由铜绿假单胞菌和洋葱状芽孢杆菌复合物菌株产生的细菌群体感应信号分子，群体感应是细菌用来控制基因表达以响应细胞密度增加的调节系统。N-3-oxo-dodecanoyl-L-Homoserine lactone 诱导 16HBE 人支气管上皮细胞产生 IL-8。
T83735	Pap12-6 TFA
	Pap12-6是一种从蝶类P. xuthus幼虫中发现的papiliocin十二个N-端氨基酸衍生的抗菌肽。它对包括E. coli、P. aeruginosa和S. syphimurium在内的八种革兰氏阴性细菌（MIC50s = 4-8 µM）以及革兰氏阳性细菌S. aureus、耐甲氧西林的S. aureus 3126（MRSA-3126）、B. subtilis和S. epidermidis（MIC50s = 4-8 µM）具有活性，但在25 µM浓度下不影响人类红细胞、小鼠RAW 264.7巨噬细胞、人类HaCaT角质形成细胞或人类HEK293肾细胞的活性。Pap12-6在4和8 µM浓度下可引起E. coli的膜去极化。Pap12-6（10 µM）预处理可降低LPS刺激的RAW 264.7巨噬细胞中一氧化氮（NO2-）、Tnf-α和Il-6的分泌水平。在体内，Pap12-6（10 mg/kg）可以提高感染E. coli的小鼠的存活率，并且在剂量为1 mg/kg时减少感染E. coli小鼠的肺、肝和肾中菌落形成单位（CFUs）的数量。Pap12-6（1 mg/kg）在E. co...
T37362	7α-Thiomethylspironolactone
	7α-Thiomethylspironolactone is a major metabolite of the synthetic steroid spironolactone.1,2 1.Jankowski, A., Skorek-Jankowska, A., and Lamparczyk, H.Simultaneous determination of spironolactone and its metabolites in human plasmaJ. Pharm. Biomed. Anal.14(8-10)1359-1365(1996) 2.Gardiner, P., Schrode, K., Quinlan, D., et al.Spironolactone metabolism: Steady-state serum levels of the sulfur-containing metabolitesJ. Clin. Pharmacol.29(4)342-347(1989)
T38215	1-Hydroxy-ibuprofen
	1-Hydroxy Ibuprofen is a metabolite of Ibuprofen in P. australis[1]. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and COX-2 with IC50s of 13 μM and 370 μM, respectively[1]. [1]. Yujie He, et al. Metabolism of Ibuprofen by Phragmites australis: Uptake and Phytodegradation. Environ Sci Technol. 2017 Apr 18;51(8):4576-4584. [2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin ...
T14382	AZD7687	Others	Others
	AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent
T83706	BMAP 28 (bovine) TFA Cathelicidin-5 (132-158),Bovine Myeloid Antimicrobial Peptide 28
	BMAP 28是一种合成抗菌肽，对应牛防御素-5的132-158氨基酸。对大肠杆菌(E. coli)、金黄色葡萄球菌(S. aureus)、耐甲氧西林金黄色葡萄球菌(MRSA)、表皮葡萄球菌(S. epidermidis)及白色念珠菌(C. albicans)具有活性(MICs分别为2、2、4、1和8 µM)。在200 nM浓度下，BMAP 28能够使大肠杆菌的内膜渗透。在5 µM浓度下，减少Vero 76细胞中单纯疱疹病毒1型(HSV-1)的复制。在30 µM浓度下，对分离的人类红细胞引起溶血，并对分离的人类嗜中性粒细胞具有细胞毒性。BMAP 28 (0.8 mg/kg)可提高大肠杆菌或MRSA感染的小鼠的生存率，但对铜绿假单胞菌(P. aeruginosa)感染的小鼠无效。
T35494	(±)11(12)-EET
	(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms CYP2C23 and CYP2C24 while CYP2B2 produces a higher proportion of 11(S),12(R)-EET.[3]11(12)-EET has been shown, along with 8(9)-EET to play a role in the recovery of depleted calcium pools in cultured smooth muscle cells[4] It also inhibits basolateral 18-pS potassium channels in t...
T35671	Salazinic Acid
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30.8 mM). Salazinic acid is cytotoxic to MM98, A431, and HaCaT cells in crystal violet (EC50s = 159, 2,870, and 48 μM, respectively) and neutral red uptake assays (EC50s = 1,925, 1,913, and 907 μM, respectively).2 It increases the wound closure rate in scratch-wounded HaCaT monolay...
T36806	TPC2-A1-P TPC2-A1-P
	TPC2-A1-P is a powerful and membrane permeable agonist of two pore channel 2 (TPC2) with an EC50 of 10.5 μM. TPC2-A1-P plays its role by mimicking the physiological actions of PI(3,5)P2. TPC2-A1-P also shows higher potency to induce Na2+ mobilisation from TPC2 than TPC-A1-N . TPC2-A1-P can be used to probe different functions of TPC2 channels in intact cells[1][2][3]. Two-pore channels (TPC1-3) are ancient members of the voltage-gated ion channel superfamily. TPCs are expressed throughout the en...
T36648	Tucatinib hemiethanolate
	Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-fold selective for HER2 versus EGFR in cell-based assays. Tucatinib selectively inhibits the receptor tyrosine kinase HER2 relative to EGFR[1].Tucatinib blocks proliferation and the phosphorylation of HER2 and its downstream effector, Akt in HER2 overexpressing cell lines. In the ...
T36629	Givinostat
	Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF3056. At 25, 50, and 100 nM, Givinostat reduced IL-1β secretion more than 70%. Givinostat (ITF-2357) suppresses the production of IL-6 in PBMCs stimulated with TLR agonists as well as the combination of IL-12 plus IL-18. IL-6 secretion decreases to 50% at 50 nM Givinostat, but at 1...
T35829	CC-90005
	CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by IL-2 expression[1]. CC-90005 shows the exquisite selectivity of CC-90005, with IC50s for all other family members of >3 μM[1].CC-90005 is a moderate inhibitor of both CYP2C9 (IC50=8 μM) and CYP2C19 (IC50=5.9 μM) in human liver microsomes[1].CC-90005 inhibits IL-2 expression in LRS...
T35840	4-Amino-6-chloro-1,3-benzenedisulfonamide
	4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3References1. Nishimori, I., Vullo, D., Minakuchi, T., et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies ...
T35757	Beauvericin A
	Beauvericin A is a cyclodepsipeptide and derivative of beauvericin originally isolated fromB. bassianathat has diverse biological activities.1,2,3It is active againstM. tuberculosis(MIC = 25 μg/ml) andP. falciparum(IC50= 12 μg/ml).2Beauvericin A is toxic to brine shrimp (LD100= 32 μg/ml).3 1.Gupta, S., Montillor, C., and Hwang, Y.-S.Isolation of Novel Beauvericin Analogues from the Fungus Beauveria bassianaJ. Nat. Prod.58(5)733-738(1995) 2.Nilanonta, C., Isaka, M., Kittakoop, P., et al.Antimycob...
T36521	Alaproclate (hydrochloride)
	Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons (IC50s = 1.1 and 6.9 μM, respectively) and does not inhibit GABA-evoked currents when used at concentratio...
T37761	Fura-FF (potassium salt)
	Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation.[1] Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively).[1],[2]However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presen...

化合物

Benzamide, N-(8-(p-aminophenoxy)octyl)-

Cat.No: T30344

Aniline, N-methyl-p-(8-phenoxyoctyloxy)-

Cat.No: T30068

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

Cat.No: TP1931L1

Synonym: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)

Target: cholecystokinin

[D-p-Cl-Phe6,Leu17]-VIP acetate

Cat.No: TP2103L

Target: Others

Laminin B1 octapeptide P-8

Cat.No: TP2389

Synonym: Asp-pro-gln-tyr-ile-gln-ser-arg,Dpgyigsr

Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate

Cat.No: T40685L

Synonym: Orphan GPCR SP9155 agonist P550 (mouse, rat) acetate (600171-70-8 Free base)

Target: Others

Cetirizine dihydrochloride

Cat.No: T0089

Synonym: 盐酸西替利嗪,P071,UCB P071,Cetirizine DiHCl

Target: Histamine Receptor

NY-BR-1 p904 A2 acetate(347142-73-8 free base)

Cat.No: TP1549L

Target: Others

Cat.No: T9150

Synonym: 1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-

Target: Apoptosis, Others, DNA/RNA Synthesis

TRPM8 antagonist WS-3

Cat.No: T5962

Synonym: Cyclohexanecarboxamide,N-乙基-5-甲基-2-(1-甲基乙基)环己甲酰胺,N-Ethyl-p-menthane-3-carboxamide,N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide

Target: TRP/TRPV Channel

Cat.No: T39826

Synonym: CBP/p300-IN-8

8-p-Coumaroylharpagide

Cat.No: T124022

IACS-9571 Hydrochloride (1800477-30-8 free base)

Cat.No: T11597L

Synonym: IACS-9571 Hydrochloride,ASIS-P040 Hydrochloride

Target: Epigenetic Reader Domain

Cat.No: T5952

Synonym: 烯唑醇,Rac-diniconazole

Target: Antibacterial

Cat.No: T36949

Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Cat.No: T14492

Target: Others

(32-Carbonyl)-RMC-5552

Cat.No: T39958

8-Hydroxyadenosine

Cat.No: TNU0199

Cat.No: T28348

Synonym: PD404182,PD-404182

1-(P-Toluenesulfonyl)imidazole

Cat.No: T67054

Cat.No: T64762

Antimalarial agent 8

Cat.No: T62936

L-Leucine benzyl ester p-toluenesulfonate salt

Cat.No: T65805

Cat.No: TMIH-0297

Ac-Ile-Glu-Thr-Asp-pNA

Cat.No: T39672

3-Deoxy-1,2-O-isopropylidene-5-O-(p-toluoyl)- α-D-glycero-pent-3-enofuranose

Cat.No: TNU1040

Cat.No: T74496

Anti-infective agent 1

Cat.No: T60315

1,2,3,6,7,8-Hexachlorodibenzo-p-dioxin

Cat.No: T83826

Synonym: 1,2,3,6,7,8-HxCDD,PCDD 67

Ciprofibrate impurity A

Cat.No: T36076

Cat.No: T80274

PACAP (1-38), human, ovine, rat TFA

Cat.No: TP1054

Synonym: Pituitary Adenylate Cyclase Activating Polypeptide 38 (TFA)

Cat.No: T70507

Cat.No: T36746

N-3-oxo-dodecanoyl-L-Homoserine lactone

Cat.No: T21633

Cat.No: T83735

7α-Thiomethylspironolactone

Cat.No: T37362

1-Hydroxy-ibuprofen

Cat.No: T38215

Cat.No: T14382

Target: Others

BMAP 28 (bovine) TFA

Cat.No: T83706

Synonym: Cathelicidin-5 (132-158),Bovine Myeloid Antimicrobial Peptide 28

Cat.No: T35494

Cat.No: T35671

Cat.No: T36806

Synonym: TPC2-A1-P

Tucatinib hemiethanolate

Cat.No: T36648

Cat.No: T36629

Cat.No: T35829

4-Amino-6-chloro-1,3-benzenedisulfonamide

Cat.No: T35840

Cat.No: T35757

Alaproclate (hydrochloride)

Cat.No: T36521

Fura-FF (potassium salt)

Cat.No: T37761

Cat. No.	Product Name	Target	Signaling Pathways
TN4729	p-Menth-8-ene-1,2-diol	Others	Others
	p-Menth-8-ene-1,2-diol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4729，CAS号为 57457-97-3。
TN5868	8-Hydroxythymol p-Cymene-3,8-diol,8-羟基百里香酚
	8-Hydroxythymol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5868，CAS号为 4478-33-5。
TN1343	8-Geranyloxypsoralen 8-香叶草氧基补骨脂素	Anti-infection; P450; BACE	Metabolism; Microbiology/Virology; Neuroscience
	8-Geranyloxypsoralen 是一种呋喃香豆素，分离自葡萄柚，是 P450 3A4 的有效抑制剂(IC50:3.93 μM)。
T13617	cis-p-Menthan-1,8-diol 4-p-Menthan-1,8-diol	Others	Others
	cis- p- Menthan- 1, 8- diol is a natural menthane monoterpenoid.
TN5238	Viscidulin II	IL Receptor; TNF	Apoptosis; Immunology/Inflammation
	Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates.
TN5729	Giffonin P
	Giffonin P 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5729，CAS号为 1830306-93-8。
TN3494	Benzoylgomisin P	Others	Others
	Benzoylgomisin P 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3494，CAS号为 129445-43-8。
TN5971	16-Oxolyclanitin-29-yl p-coumarate
	16-Oxolyclanitin-29-yl p-coumarate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5971，CAS号为 140701-70-8。
TN5833	6-O-(p-Hydroxybenzoyl)glucose
	6-O-(p-Hydroxybenzoyl)glucose 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5833，CAS号为 202337-44-8。
TN6304	Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside
	Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6304，CAS号为 71781-79-8。
TN3292	8-Prenyldaidzein	Others	Others
	8-Prenyldaidzein has cytotoxic properties against P-388 cells, its IC 50 values 5.82 ug/mL, it also exhibits very high antioxidant activity against DPPH radical scavenging.
TN6287	Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside Anisofolin B
	Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6287，CAS号为 1448779-19-8。
T40859	5-Hydroxy-8-methoxypsoralen 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen
	5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite derived from Xanthotoxin, which acts as a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). It is employed as an agent for the treatment of psoriasis, eczema, vitiligo, and certain cutaneous Lymphomas, in combination with phototherapy involving exposure to sunlight.
T38015	Herquline A
	Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively).
T38262	Sphingosine (d14:1)
	Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively).
T35754	Aszonapyrone A
	Aszonapyrone A is a meroditerpene fungal metabolite that has been found in Neosartorya and has diverse biological activities.1,2,3 It inhibits the growth of MCF-7, NCI H460, and A375-C5 cancer cells (GI50s = 13.6, 11.6, and 10.2 μM, respectively).1 Aszonapyrone A is active against multidrug-resistant isolates of S. aureus, E. faecalis, and E. faecium (MICs = 8, 16, and 16 μg/ml, respectively) and inhibits S. aureus biofilm formation.2 It is also active against P. falciparum in vitro (IC50 = 1.34...
T36329	Terpendole I
	Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml).1,2 It is cytotoxic to HeLa cells with an IC50 value of 52.6 μM.3 \|1. Tomoda, H., Tabata, N., Yang, D.-J., et al. Ter...
T36000	3-Hydroxyterphenyllin
	3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,3,4 It has a 96% scavenging effect on 2,2-diphenyl-1-picrylhydrazyl radicals when used at a concentration of 100 μg/ml.2 3-Hydroxyterphenyllin inhibits the growth of HeLa cervical, A549 lung, and HepG2 liver cancer cells (IC50s = 23, 36, and 32 μM, respectively), as well as methi...
T35750	Trypacidin
	Trypacidin is a fungal metabolite originally isolated fromA. fumigatus.1It is active againstB. subtilisandM. bovis(MICs = 12.5 and 1.25 μg/ml, respectively), as well asT. cruziandT. gondii(MICs = 5-10 and 10-20 μg/ml, respectively).1,2It reduces viability and induces lysis of A549 human lung cancer cells (IC50s = 7.4 μM for both).3Trypacidin increases survival in a mouse model ofT. gondiiinfection when administered in six doses of 12.5 mg/kg each.1 1.Balan, J., Ebringer, L., Nemec, P., et al.Ant...

天然产物

p-Menth-8-ene-1,2-diol

Cat.No: TN4729

Target: Others

8-Hydroxythymol

Cat.No: TN5868

Synonym: p-Cymene-3,8-diol,8-羟基百里香酚

8-Geranyloxypsoralen

Cat.No: TN1343

Synonym: 8-香叶草氧基补骨脂素

Target: Anti-infection, P450, BACE

cis-p-Menthan-1,8-diol

Cat.No: T13617

Synonym: 4-p-Menthan-1,8-diol

Target: Others

Cat.No: TN5238

Target: IL Receptor, TNF

Cat.No: TN5729

Benzoylgomisin P

Cat.No: TN3494

Target: Others

16-Oxolyclanitin-29-yl p-coumarate

Cat.No: TN5971

6-O-(p-Hydroxybenzoyl)glucose

Cat.No: TN5833

Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside

Cat.No: TN6304

8-Prenyldaidzein

Cat.No: TN3292

Target: Others

Apigenin 7-O-(2'',6''-di-O-E-p-coumaroyl)glucoside

Cat.No: TN6287

Synonym: Anisofolin B

5-Hydroxy-8-methoxypsoralen

Cat.No: T40859

Synonym: 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen

Cat.No: T38015

Sphingosine (d14:1)

Cat.No: T38262

Cat.No: T35754

Cat.No: T36329

3-Hydroxyterphenyllin

Cat.No: T36000

Cat.No: T35750

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01356	S100A8 Protein, Human, Recombinant (His) 60B8AG,MRP-8,MA387,NIF,L...	Human	Baculovirus Insect Cells
	S100A8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is P05109.
TMPY-02215	Coagulation factor IX/F9 Protein, Human, Recombinant (His) FIX,PTC,Coagulation factor 9,coagulation factor IX,...	Human	HEK293 Cells
	Coagulation factor IX/F9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is AAB59620.1.
TMPY-01563	PMP2 Protein, Human, Recombinant (His) MP2,FABP8,perip...	Human	E. coli
	Myelin P2 protein, also known as PMP2, is a cytosolic protein found primarily in peripheral nerves. It Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. It is similar in amino acid sequence and tertiary structure to fatty acid binding proteins found in the liver, adipocytes, and intestine, its expression is limited to the nervous system. PMP2 is detected only in myelin-producing cells ...
TMPY-05355	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) P19,Coagulation factor 9,HEMB,FIX,THPH...	Human	HEK293 Cells
	Coagulation factor IX/F9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.5 kDa and the accession number is P00740-1.
TMPH-03625	Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) Tityustoxin II,TsTX III-8,Toxin II,Tst2,Toxin T1-IV...	Tityus serrulatus	Baculovirus Insect Cells
	Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 10.9 kDa and the accession number is P68410.
TMPH-01186	CYP2C9 Protein, Human, Recombinant (His & Myc) CYP2C10,Cytochrome P450 2C9,S-mep...	Human	E. coli
	CYP2C9 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-04123	CEACAM1 Protein, Human, Recombinant (His & hFc) CEACAM‑1,carcinoembryonic antigen-related cell adhesion mole...	Human	HEK293 Cells
	CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPY-06676	Cor a 8 Protein, Corylus avellana, Recombinant	Corylus avellana	P. pastoris (Yeast)
	Cor a 8 Protein, Corylus avellana, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 9 kDa.
TMPY-06668	Act d 8 Protein, Actinidia deliciosa, Recombinant	Actinidia deliciosa	P. pastoris (Yeast)
	Act d 8 Protein, Actinidia deliciosa, Recombinant is expressed in P. pastoris yeast expression system. The predicted molecular weight is 26.7 kDa.
TMPH-02295	UAP1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
TMPH-02294	UAP1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Converts UTP and GlcNAc-1-P into UDP-GlcNAc, and UTP and GalNAc-1-P into UDP-GalNAc. Isoform AGX1 has 2 to 3 times higher activity towards GalNAc-1-P, while isoform AGX2 has 8 times more activity towards GlcNAc-1-P.
TMPJ-00808	CD45RA Protein, Human, Recombinant (His) PTPRC,CD45R,CD45,LCA,protein tyro...	Human	HEK293 Cells
	CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPH-01705	Mucin-1/MUC1 Protein, Human, Recombinant (His)	Human	E. coli
	Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPJ-00828	Tau-F Protein, Human, Recombinant Neurofibrillary tangle protein,Paired heli...	Human	E. coli
	Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def...
TMPY-00717	CEACAM1 Protein, Human, Recombinant (His) CEACAM‑1,BGP1,BGP,carcinoembryonic antigen...	Human	HEK293 Cells
	CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
TMPY-06707	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surfac...	Human	HEK293 Cells
	Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-01330	CD299 Protein, Human, Recombinant (His & Flag) DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin do...	Human	HEK293 Cells
	CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPY-00668	APP/Protease nexin-II Protein, Human, Recombinant (hFc) CTFγ,amyloid beta (A4) precursor protein,A...	Human	HEK293 Cells
	APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.

重组蛋白

S100A8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01356

Species: Human

Expression System: Baculovirus Insect Cells

Coagulation factor IX/F9 Protein, Human, Recombinant (His)

Cat.No: TMPY-02215

Species: Human

Expression System: HEK293 Cells

PMP2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01563

Species: Human

Expression System: E. coli

Coagulation factor IX/F9 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05355

Species: Human

Expression System: HEK293 Cells

Alpha-mammal toxin Ts2 Protein, Tityus serrulatus, Recombinant (His & Myc)

Cat.No: TMPH-03625

Species: Tityus serrulatus

Expression System: Baculovirus Insect Cells

CYP2C9 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01186

Species: Human

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-04123

Species: Human

Expression System: HEK293 Cells

Cor a 8 Protein, Corylus avellana, Recombinant

Cat.No: TMPY-06676

Species: Corylus avellana

Expression System: P. pastoris (Yeast)

Act d 8 Protein, Actinidia deliciosa, Recombinant

Cat.No: TMPY-06668

Species: Actinidia deliciosa

Expression System: P. pastoris (Yeast)

UAP1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02295

Species: Human

Expression System: P. pastoris (Yeast)

UAP1 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02294

Species: Human

Expression System: E. coli

CD45RA Protein, Human, Recombinant (His)

Cat.No: TMPJ-00808

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01705

Species: Human

Expression System: E. coli

Tau-F Protein, Human, Recombinant

Cat.No: TMPJ-00828

Species: Human

Expression System: E. coli

CEACAM1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00717

Species: Human

Expression System: HEK293 Cells

Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

Cat.No: TMPY-06707

Species: Human

Expression System: HEK293 Cells

CD299 Protein, Human, Recombinant (His & Flag)

Cat.No: TMPJ-01330

Species: Human

Expression System: HEK293 Cells

APP/Protease nexin-II Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00668

Species: Human

Expression System: HEK293 Cells

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